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2021

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Effects Of Human Activities On The Afaka Afforestation Project, Kaduna North, Kaduna State, Nigeria, Mamman Shaba Jibril, Mary Oluyemisi Ariyo, Ali Williams Butu, Chukwudi Nnaemeka Emeribe Dec 2021

Effects Of Human Activities On The Afaka Afforestation Project, Kaduna North, Kaduna State, Nigeria, Mamman Shaba Jibril, Mary Oluyemisi Ariyo, Ali Williams Butu, Chukwudi Nnaemeka Emeribe

Jurnal Geografi Lingkungan Tropik (Journal of Geography of Tropical Environments)

The study aimed to investigate the effects of human activities on the Afaka afforestation project, Kaduna State, Nigeria. Structured interview was used to evaluate the level of community involvement in the modification of the forest project, their perceived environmental effects of landcover loss. Landsat images of 1986, 1999 and Sentinel-2 image of 2017 were applied for detection of changes in land use/land cover over the years (1986-2017). The study found that the land cover structure of the forest reserve has changed significantly. In 1986, area under crop cultivation was 19.24%, built-up areas, 0.08%, disturbed forest, 7.57%, gully, 2.60%, riparian vegetation, …

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Climatic Factors Affecting Maize Grain Yield In Different Growing Areas Of The Philippines, Lakshman Kumara, Tonette Laude, Jose Hernandez, Pearl Sanchez, Moises Dorado, Jose Nestor Garcia, Gerardo Gauna, Pompe C. Sta. Cruz Dec 2021

Climatic Factors Affecting Maize Grain Yield In Different Growing Areas Of The Philippines, Lakshman Kumara, Tonette Laude, Jose Hernandez, Pearl Sanchez, Moises Dorado, Jose Nestor Garcia, Gerardo Gauna, Pompe C. Sta. Cruz

The Philippine Agricultural Scientist

Seasonal climate variation is one of the problems faced by Filipino maize farmers, due to varying climatic elements such as solar radiation, rainfall, relative humidity, and air temperature. This study determined the seasonal productivity of selected maize varieties in the major growing areas in the Philippines, and identified the yield-limiting climatic factors specific to location and growing season. Grain yield, covering two wet and dry seasons (2016-2018) from seven field trials (representing 3 climatic types) of the National Corn Testing (NCT) were used in the study. Climatic data (2016-2018) were gathered from the PAGASA weather station nearest to the trial …

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Characterization Of Dirt On White-Shelled Table Eggs Through Image Analysis [Research Note], Maria Patricia Azanza, Dominic Panaligan, Bryan Kenneth Desierdo Dec 2021

Characterization Of Dirt On White-Shelled Table Eggs Through Image Analysis [Research Note], Maria Patricia Azanza, Dominic Panaligan, Bryan Kenneth Desierdo

The Philippine Agricultural Scientist

The study reports the laboratory-scale use of image analysis to categorize dirty white-shelled table eggs. Data generated from image analysis were subjected to statistical analysis and compared with established standards categorizing dirty white-shelled table eggs for washing and sanitation or for use in food processing. The average Quartile 1 (2.49%) and Quartile 3 (9.28%) values of percent surface dirt were found to be proximate to quality standard guidelines values of ≤ 3.12% and < 10% from USDA (2000) and PNS (2005), respectively. These limits were recommended as possible guidelines for classifying eggs into those that are acceptable as table eggs, acceptable for processing with washing and sanitation, and unacceptable for food use.

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Activation Of Crtc2/Creb1 In Skeletal Muscle Enhances Weight Loss During Intermittent Fasting, Nelson E Bruno, Jerome C Nwachukwu, David C Hughes, Sathish Srinivasan, Richard Hawkins, David Sturgill, Gordon L Hager, Stephen Hurst, Shey-Shing Sheu, Sue C Bodine, Michael D Conkright, Kendall W Nettles Dec 2021

Activation Of Crtc2/Creb1 In Skeletal Muscle Enhances Weight Loss During Intermittent Fasting, Nelson E Bruno, Jerome C Nwachukwu, David C Hughes, Sathish Srinivasan, Richard Hawkins, David Sturgill, Gordon L Hager, Stephen Hurst, Shey-Shing Sheu, Sue C Bodine, Michael D Conkright, Kendall W Nettles

Department of Medicine Faculty Papers

The Creb-Regulated Transcriptional Coactivator (Crtc) family of transcriptional coregulators drive Creb1-mediated transcription effects on metabolism in many tissues, but the in vivo effects of Crtc2/Creb1 transcription on skeletal muscle metabolism are not known. Skeletal muscle-specific overexpression of Crtc2 (Crtc2 mice) induced greater mitochondrial activity, metabolic flux capacity for both carbohydrates and fats, improved glucose tolerance and insulin sensitivity, and increased oxidative capacity, supported by upregulation of key metabolic genes. Crtc2 overexpression led to greater weight loss during alternate day fasting (ADF), selective loss of fat rather than lean mass, maintenance of higher energy expenditure during the fast and reduced binge-eating …

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The Genome Of The Stable Fly, Stomoxys Calcitrans, Reveals Potential Mechanisms Underlying Reproduction, Host Interactions, And Novel Targets For Pest Control, Pia U. Olafson, Serap Aksoy, Geoffrey M. Attardo, Greta Buckmeier, Xiaoting Chen, Craig J. Coates, Megan Davis, Justin Dykema, Scott J. Emrich, Markus Friedrich, Christopher J. Holmes, Panagiotis Ioannidis, Evan N. Jansen, Emily C. Jennings, Daniel Lawson, Ellen O. Martinson, Gareth L. Maslen, Richard P. Meisel, Terence D. Murphy, Dana Nayduch, David R. Nelson, Kennan J. Oyen, Tyler J. Raszick, José M.C. Ribeiro, Hugh M. Robertson, Andrew J. Rosendale, Timothy B. Sackton, Perot Saelao, Sonja L. Swiger, Sing Hoi Sze, Aaron M. Tarone, David B. Taylor, Wesley C. Warren, Robert M. Waterhouse, Matthew T. Weirauch, John H. Werren, Richard K. Wilson, Evgeny M. Zdobnov, Joshua B. Benoit Dec 2021

The Genome Of The Stable Fly, Stomoxys Calcitrans, Reveals Potential Mechanisms Underlying Reproduction, Host Interactions, And Novel Targets For Pest Control, Pia U. Olafson, Serap Aksoy, Geoffrey M. Attardo, Greta Buckmeier, Xiaoting Chen, Craig J. Coates, Megan Davis, Justin Dykema, Scott J. Emrich, Markus Friedrich, Christopher J. Holmes, Panagiotis Ioannidis, Evan N. Jansen, Emily C. Jennings, Daniel Lawson, Ellen O. Martinson, Gareth L. Maslen, Richard P. Meisel, Terence D. Murphy, Dana Nayduch, David R. Nelson, Kennan J. Oyen, Tyler J. Raszick, José M.C. Ribeiro, Hugh M. Robertson, Andrew J. Rosendale, Timothy B. Sackton, Perot Saelao, Sonja L. Swiger, Sing Hoi Sze, Aaron M. Tarone, David B. Taylor, Wesley C. Warren, Robert M. Waterhouse, Matthew T. Weirauch, John H. Werren, Richard K. Wilson, Evgeny M. Zdobnov, Joshua B. Benoit

United States Department of Agriculture-Agricultural Research Service / University of Nebraska-Lincoln: Faculty Publications

Background: The stable fly, Stomoxys calcitrans, is a major blood-feeding pest of livestock that has near worldwide distribution, causing an annual cost of over $2 billion for control and product loss in the USA alone. Control of these flies has been limited to increased sanitary management practices and insecticide application for suppressing larval stages. Few genetic and molecular resources are available to help in developing novel methods for controlling stable flies. Results: This study examines stable fly biology by utilizing a combination of high-quality genome sequencing and RNA-Seq analyses targeting multiple developmental stages and tissues. In conjunction, 1600 genes were …

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Swallow's Nest: Birdwatching Poems, Karissa Wehri Dec 2021

Swallow's Nest: Birdwatching Poems, Karissa Wehri

Greenway Press Chapbooks

No abstract provided.

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The Year Of Brood Viii, Jona L. Pederson Dec 2021

The Year Of Brood Viii, Jona L. Pederson

Greenway Press Chapbooks

No abstract provided.

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Pause: The Writer's Block Literary Magazine, Covid Edition, December 2021, The Writer's Block Dec 2021

Pause: The Writer's Block Literary Magazine, Covid Edition, December 2021, The Writer's Block

The Writer's Block Literary Magazine

No abstract provided.

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Corticothalamic Projections Deliver Enhanced Responses To Medial Geniculate Body As A Function Of The Temporal Reliability Of The Stimulus, Srinivasa P Kommajosyula, Edward L Bartlett, Rui Cai, Lynne Ling, Donald M Caspary Dec 2021

Corticothalamic Projections Deliver Enhanced Responses To Medial Geniculate Body As A Function Of The Temporal Reliability Of The Stimulus, Srinivasa P Kommajosyula, Edward L Bartlett, Rui Cai, Lynne Ling, Donald M Caspary

Articles

Ageing and challenging signal-in-noise conditions are known to engage the use of cortical resources to help maintain speech understanding. Extensive corticothalamic projections are thought to provide attentional, mnemonic and cognitive-related inputs in support of sensory inferior colliculus (IC) inputs to the medial geniculate body (MGB). Here we show that a decrease in modulation depth, a temporally less distinct periodic acoustic signal, leads to a jittered ascending temporal code, changing MGB unit responses from adapting responses to responses showing repetition enhancement, posited to aid identification of important communication and environmental sounds. Young-adult male Fischer Brown Norway rats, injected with the inhibitory …

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The Lumberjack, December 01, 2021 Dec 2021

The Lumberjack, December 01, 2021

Cal Poly Humboldt's Student Newspaper

The student newspaper of Humboldt State University.

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Emsee, Jaclyn G. Napoli Dec 2021

Emsee, Jaclyn G. Napoli

Graphic Communication

To create an application that achieves safety on the road for first responders and bystanders through the use of location in GPS navigation and volume control. This app would signal smart phone devices in surrounding cars to limit distractions by objectively decreasing their vehicle audio so the public is alert of the first responders driving to their destination. There is a short amount of time to process where the emergency vehicle is once you see lights or hear sirens. However, if one or both of these senses are impaired by distractions of the bystander, this could result in danger of …

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Vol. 99, No. 2: Table Of Contents, Denver Law Review Dec 2021

Vol. 99, No. 2: Table Of Contents, Denver Law Review

Denver Law Review

No abstract provided.

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Vol. 99, No. 2: Full Issue, Denver Law Review Dec 2021

Vol. 99, No. 2: Full Issue, Denver Law Review

Denver Law Review

No abstract provided.

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Dietary Supplementation Of Bacillus-Based Probiotics On The Growth Performance, Gut Morphology, Intestinal Microbiota And Immune Response In Low Biosecurity Broiler Chickens, Mohammad Arif, Md Akteruzzaman, Tuhin-Al-Ferdous, Sk Shaheenur Islam, Bidhan Chandra Das, Mahbubul Pratik Siddique, S M Lutful Kabir Dec 2021

Dietary Supplementation Of Bacillus-Based Probiotics On The Growth Performance, Gut Morphology, Intestinal Microbiota And Immune Response In Low Biosecurity Broiler Chickens, Mohammad Arif, Md Akteruzzaman, Tuhin-Al-Ferdous, Sk Shaheenur Islam, Bidhan Chandra Das, Mahbubul Pratik Siddique, S M Lutful Kabir

Faculty, Staff and Student Publications

A feeding trial was conducted to evaluate the effects of Bacillus-based probiotics on growth performance, intestinal histo-morphology, gut microbial population and immune response in broilers. A total of 2000 Hubbard Classic day-old chicks were randomly enrolled in four experimental groups and 4 replicates of 500 birds in each group, and reared for 35 days under a low- level of biosecurity measures. The trial groups were assigned treatment-1 (T1): basal diet(control), treatment-2 (T2): basal diet plus Bacillus licheniformis (DSM17236), treatment-3 (T3): basal diet plus Bacillus subtilis (PB6), and treatment-4 (T4) basal diet plus 4% Flavomycin. All four groups were fed …

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Γδ T Cell Ifnγ Production Is Directly Subverted By Yersinia Pseudotuberculosis Outer Protein Yopj In Mice And Humans, Timothy H. Chu, Camille Khairallah, Jason Shieh, Rhea Cho, Zhijuan Qiu, Yue Zhang, Onur Eskiocak, David G. Thanassi, Mark H. Kaplan, Semir Beyaz, Vincent W. Yang, James B. Bliska, Brian S. Sheridan Dec 2021

Γδ T Cell Ifnγ Production Is Directly Subverted By Yersinia Pseudotuberculosis Outer Protein Yopj In Mice And Humans, Timothy H. Chu, Camille Khairallah, Jason Shieh, Rhea Cho, Zhijuan Qiu, Yue Zhang, Onur Eskiocak, David G. Thanassi, Mark H. Kaplan, Semir Beyaz, Vincent W. Yang, James B. Bliska, Brian S. Sheridan

Dartmouth Scholarship

Yersinia pseudotuberculosis is a foodborne pathogen that subverts immune function by translocation of Yersinia outer protein (Yop) effectors into host cells. As adaptive γδ T cells protect the intestinal mucosa from pathogen invasion, we assessed whether Y. pseudotuberculosis subverts these cells in mice and humans. Tracking Yop translocation revealed that the preferential delivery of Yop effectors directly into murine Vγ4 and human Vδ2+ T cells inhibited anti-microbial IFNγ production. Subversion was mediated by the adhesin YadA, injectisome component YopB, and translocated YopJ effector. A broad anti-pathogen gene signature and STAT4 phosphorylation levels were inhibited by translocated YopJ. Thus, Y. pseudotuberculosis …

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A Distributed Fmri-Based Signature For The Subjective Experience Of Fear, Feng Zhou, Weihua Zhao, Ziyu Qi, Yayuan Geng, Shuxia Yao, Keith M. Kendrick, Tor D. Wager, Benjamin Becker Dec 2021

A Distributed Fmri-Based Signature For The Subjective Experience Of Fear, Feng Zhou, Weihua Zhao, Ziyu Qi, Yayuan Geng, Shuxia Yao, Keith M. Kendrick, Tor D. Wager, Benjamin Becker

Dartmouth Scholarship

The specific neural systems underlying the subjective feeling of fear are debated in affective neuroscience. Here, we combine functional MRI with machine learning to identify and evaluate a sensitive and generalizable neural signature predictive of the momentary self-reported subjective fear experience across discovery (n = 67), validation (n = 20) and generalization (n = 31) cohorts. We systematically demonstrate that accurate fear prediction crucially requires distributed brain systems, with important contributions from cortical (e.g., prefrontal, midcingulate and insular cortices) and subcortical (e.g., thalamus, periaqueductal gray, basal forebrain and amygdala) regions. We further demonstrate that the neural representation of subjective fear …

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Spectral Analysis Of Climate Dynamics With Operator-Theoretic Approaches, Gary Froyland, Dimitrios Giannakis, Benjamin R. Lintner, Maxwell Pike, Joanna Slawinska Dec 2021

Spectral Analysis Of Climate Dynamics With Operator-Theoretic Approaches, Gary Froyland, Dimitrios Giannakis, Benjamin R. Lintner, Maxwell Pike, Joanna Slawinska

Dartmouth Scholarship

The Earth’s climate system is a classical example of a multiscale, multiphysics dynamical system with an extremely large number of active degrees of freedom, exhibiting variability on scales ranging from micrometers and seconds in cloud microphysics, to thousands of kilometers and centuries in ocean dynamics. Yet, despite this dynamical complexity, climate dynamics is known to exhibit coherent modes of variability. A primary example is the El Niño Southern Oscillation (ENSO), the dominant mode of interannual (3–5 yr) variability in the climate system. The objective and robust characterization of this and other important phenomena presents a long-standing challenge in Earth system …

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Location Of Studies And Evidence Of Effects Of Herbivory On Arctic Vegetation: A Systematic Map, E. M. Soininen, I. C. Barrio, R. Bjørkås, K. Björnsdóttir, D. Ehrich, K. A. Hopping, E. Kaarlejärvi, A. L. Kolstad, S. Abdulmanova, R. G. Björk, C. G. Bueno, I. Eischeid, R. Finger-Higgens, J. S. Forbey, C. Gignac, O. Gilg, M. Den Herder, H. S. Holm, B. C. Hwang, J. U. Jepsen Dec 2021

Location Of Studies And Evidence Of Effects Of Herbivory On Arctic Vegetation: A Systematic Map, E. M. Soininen, I. C. Barrio, R. Bjørkås, K. Björnsdóttir, D. Ehrich, K. A. Hopping, E. Kaarlejärvi, A. L. Kolstad, S. Abdulmanova, R. G. Björk, C. G. Bueno, I. Eischeid, R. Finger-Higgens, J. S. Forbey, C. Gignac, O. Gilg, M. Den Herder, H. S. Holm, B. C. Hwang, J. U. Jepsen

Dartmouth Scholarship

Background: Herbivores modify the structure and function of tundra ecosystems. Understanding their impacts is necessary to assess the responses of these ecosystems to ongoing environmental changes. However, the effects of herbivores on plants and ecosystem structure and function vary across the Arctic. Strong spatial variation in herbivore effects implies that the results of individual studies on herbivory depend on local conditions, i.e., their ecological context. An important first step in assessing whether generalizable conclusions can be produced is to identify the existing studies and assess how well they cover the underlying environmental conditions across the Arctic. This systematic map aims …

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Turning Orphans For A Profit: The Orphan Drug Act Is Due For An Overhaul, Kelly L. Mckinney Dec 2021

Turning Orphans For A Profit: The Orphan Drug Act Is Due For An Overhaul, Kelly L. Mckinney

Hofstra Law Review

No abstract provided.

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Prenatal Exposure To Per- And Polyfluoroalkyl Substances And Child Neurodevelopment, Jiwon Oh Dec 2021

Prenatal Exposure To Per- And Polyfluoroalkyl Substances And Child Neurodevelopment, Jiwon Oh

Earth & Environmental Sciences Dissertations - Archive

Pregnant women are exposed to per- and polyfluoroalkyl substances (PFAS) primarily via ingestion of contaminated food, water, and house dust. PFAS in pregnant women can be transferred to their child through the placenta during pregnancy. Many long-chain PFAS have been frequently detected in blood of pregnant women, amniotic fluid, and umbilical cord blood for the last few decades. Prenatal exposure to PFAS has shown potential to adversely affect offspring’s neurodevelopment in laboratory animals. However, epidemiological evidence on associations between prenatal PFAS exposure and child neurodevelopment remains inconsistent. My dissertation research consists of four sub-studies whose objectives are (1) to examine …

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Can A Large-Landscape Conservation Vision Contribute To Achieving Biodiversity Targets?, Mark Hebblewhite, Jodi A. Hilty, Sara Williams, Harvey Locke, Charles Chester, David Johns, Gregory Kehm, Wendy L. Francis Dec 2021

Can A Large-Landscape Conservation Vision Contribute To Achieving Biodiversity Targets?, Mark Hebblewhite, Jodi A. Hilty, Sara Williams, Harvey Locke, Charles Chester, David Johns, Gregory Kehm, Wendy L. Francis

Political Science Faculty Publications and Presentations

Founded in 1993, the Yellowstone to Yukon (Y2Y) vision was one of the earliest large-landscape conservation visions. Despite growing recognition of large-landscape conservation strategies, there have been few tests to date of conservation gains achieved through such approaches. We tested for conservation gains in the Y2Y region of North America following initiation of the Y2Y conservation vision in 1993 using a counterfactual spatiotemporal comparison and tracking change in five different conservation metrics. First, we enumerated the area of land within Y2Y in designated protected areas. We then compared the rate of change of protected area growth before- and after-initiation of …

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Development Of Bioaffinity Based Assays For Forensic Applications, Juliana Maria Agudelo Cano Dec 2021

Development Of Bioaffinity Based Assays For Forensic Applications, Juliana Maria Agudelo Cano

Legacy Theses & Dissertations (2009 - 2024)

In the field of forensic science, body fluids are a major contributor of evidence in investigations. However, body fluids are usually used only for their genetic content, overlooking its unique composition of proteins and low-molecular-weight compounds that often serve as biomarkers in clinical diagnostics. This investigation aimed to develop simple, effective, and economical models that can be used to identify different attributes of the originator. The focus of this research was to develop biocatalytic cascades that could analyze body fluids by using UV-Vis spectroscopy. These models could be implemented in forensic settings, as well as in biometric authentications. The central …

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The Assemblage Of The Dead : Speech, Subjectivity, And Being Human, Nazia Manzoor Dec 2021

The Assemblage Of The Dead : Speech, Subjectivity, And Being Human, Nazia Manzoor

Legacy Theses & Dissertations (2009 - 2024)

ABSTRACT“The Assemblage of the Dead: Speech, Subjectivity, and Being Human” reimagines the construct of the human as a political subject of the state through a bio(necro)political lens. The project re-envisions the conceptual framework of biopolitics through an engagement with the figure of the living dead, centralized in Giorgio Agamben’s work through his casting of the figure of the Muselmann as the cipher that reveals the limits of humanity and being human. With a bid to counter-narrate the twinning of death and resistance and death and subjectivity as foundational markers of humanity in current critical scholarship of the field, this project …

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Sex Differences In Context Fear Neural Circuitry And Behavior Across Development, Lorianna Marie Colon Dec 2021

Sex Differences In Context Fear Neural Circuitry And Behavior Across Development, Lorianna Marie Colon

Legacy Theses & Dissertations (2009 - 2024)

Over the span of five decades, staggering progress has been made in elucidating the neural circuits involved in fear learning. Research focused on rodents and healthy individuals has been instrumental in elucidating how abnormalities in this circuitry may lend to increased prevalence of various fear and anxiety disorders. However, many of the key findings concerning the acquisition, storage, and retrieval of fear memories have been established in the adult male rodent, leaving a gap in knowledge as to whether females and developing animals process fear and stress inducing information in a similar fashion. Compared to men, women are twice as …

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Trauma Before The Name : Impersonal Violence In Nineteenth-Century American Literature, Carolin Alice Hofmann Dec 2021

Trauma Before The Name : Impersonal Violence In Nineteenth-Century American Literature, Carolin Alice Hofmann

Legacy Theses & Dissertations (2009 - 2024)

The dissertation studies the pre-history of trauma in US American fiction, examining how experiences of large-scale adversity are represented before the concept of psychological trauma emerges in the late nineteenth century. Distinctly modern forms of violence—diffuse, systemic, lacking direction and intent—bring forth less individual and personal experiences of grief and suffering than those imagined by twentieth-century trauma theory. Studying forms of feeling and of genre that make trauma legible historicizes the way a Western idea of modern subjectivity, as white, self-possessed, agential, and split, has shaped out understanding of how a person processes crisis. The dissertation visits three spaces that …

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The Gaze Of The Consumed : A Lacanian Approach To The Italian Cannibal Films, David Kelly Dec 2021

The Gaze Of The Consumed : A Lacanian Approach To The Italian Cannibal Films, David Kelly

Legacy Theses & Dissertations (2009 - 2024)

“The Gaze of the Consumed: A Lacanian Approach to the Italian Cannibal Films” not only acts as a brief chronicle of the subgenre of Italian exploitation films centered around cannibals, but as an exploration of the constructs that hold such a subgenre together. With a foundation in Lacanian psychoanalysis, this essay discusses the ramifications of assigning terms such as “savage” and “civilized,” as well as the issue with entering into such a discourse with presupposed Western notions of civility. The Italian cannibal films exemplify the circular nature of the mere anthropophagous act, putting forth the conceptualization of the “Gaze of …

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Preliminary Results Of Measurements Of Potentially Cancerogenic 1,4-Dioxane In Surface Water Of Twin Lakes Preserve, Wantagh, Ny, Lijo Jose Varghese Dec 2021

Preliminary Results Of Measurements Of Potentially Cancerogenic 1,4-Dioxane In Surface Water Of Twin Lakes Preserve, Wantagh, Ny, Lijo Jose Varghese

Legacy Theses & Dissertations (2009 - 2024)

1,4-dioxane is a volatile organic compound categorized by the United States Environmental Protection agency (EPA, 2017) as a possible human carcinogen potent to cause tumors in humans. Even though this compound poses significant environmental danger when it contaminates water sources, it is surprisingly less studied, and how it behaves in surface water is less understood. The biggest 1,4-dioxane plume in the United States is located in Long Island region of New York. The purpose of this study was to investigate the presence of 1,4-dioxane in surface water and document the influence of existing 1,4-dioxane plume to Twin Lakes Preserve. To …

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Development Of Sense Of Place Through An Urban Citizen Science Program, Cornelia Harris Dec 2021

Development Of Sense Of Place Through An Urban Citizen Science Program, Cornelia Harris

Legacy Theses & Dissertations (2009 - 2024)

Citizen science programs are a way for participants to develop a sense of place, which has been theorized to lead to pro-environmental behaviors. In this mixed-methods study, I document how a citizen science program encourages urban youth to connect with their place, and notice how both joy and wonder are developed as they experience a stunning migratory event with a unique organism, the American eel. Students were excited to be in a creek and to ‘discover’ a new creature in a place that they had walked past for years, one that was merely a backdrop to their lives prior to …

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Empowering Melatonin Therapeutics With Drosophila Models, Cassandra Millet-Boureima, Caroline C. Ennis, Jurnee Jamison, Shana Mcsweeney, Anna Park, Chiara Gamberi Dec 2021

Empowering Melatonin Therapeutics With Drosophila Models, Cassandra Millet-Boureima, Caroline C. Ennis, Jurnee Jamison, Shana Mcsweeney, Anna Park, Chiara Gamberi

Biology

Melatonin functions as a central regulator of cell and organismal function as well as a neurohormone involved in several processes, e.g., the regulation of the circadian rhythm, sleep, aging, oxidative response, and more. As such, it holds immense pharmacological potential. Receptor-mediated melatonin function mainly occurs through MT1 and MT2, conserved amongst mammals. Other melatonin-binding proteins exist. Non-receptor-mediated activities involve regulating the mitochondrial function and antioxidant cascade, which are frequently affected by normal aging as well as disease. Several pathologies display diseased or dysfunctional mitochondria, suggesting melatonin may be used therapeutically. Drosophila models have extensively been employed to study disease pathogenesis …

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The Physiological Benefits Of A Plant-Based Diet On Cardiovascular Health, Jenevieve Petray Dec 2021

The Physiological Benefits Of A Plant-Based Diet On Cardiovascular Health, Jenevieve Petray

Nursing | Senior Theses

Cardiovascular disease (CVD) is increasingly more prevalent in today’s society and is attributed to an alarming percentage of American hospitalizations and deaths. Americans are unhealthier than ever before, and the main contributor is the Western diet. Diet is a double-edged sword that can offer benefits or detriments to one’s health. CVD encompasses numerous diagnoses originating from various underlying physiological alterations. These alterations are downstream effects of increased body weight and BMI, increased cholesterol levels, decreased insulin sensitivity and increased arterial plaque buildup. Research shows that a plant-based diet has the potential to manage and reverse all fundamental physiological alterations that …

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