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The Cellular And Genetic Mechanisms Of Stress Response Pathways In Caribbean Coral, Bradford Austin Dimos

Biology Dissertations - Archive

Reef-building corals are in decline around the globe due to both the effects of increased ocean temperatures and the emergence of marine diseases which affect corals. These emerging issues threaten the continued persistence of reefs and the ecosystem which they form as the mechanisms which corals use to respond to stress remain poorly characterized, limiting the success of interventions aimed at reversing these declines. To address these issues my dissertation focused on uncovering the cellular and genetic mechanism utilized by Caribbean corals during periods of stress. Towards this aim my second chapter identified and characterized a mitochondrial stress response pathway …

Is It A Boy Or A Girl? Constructing A Gendered Identity For Our Companion Animals, Jennifer Ann Wellman

Sociology & Anthropology Theses - Archive

A qualitative study of the differences in how we gender our cats and our dogs. Fifty women between the ages of 18 and 50 were interviewed, who kept cats, dogs, or both cats and dogs. Differences were found in how naming cats, with cats being given less humanized gendered names. It was found that cats are treated more as an extension of the self while dogs were given more of a gendered identity of their own.

Synching Science And Policy To Address Climate Change In Tribal Communities, John C. Ruple, Heather Tanana

Utah Law Faculty Scholarship

Climate change is a global environmental problem, and yet, the adverse impacts of climate change are disproportionately felt in tribal communities. There are 574 federally recognized tribes in the United States. While each tribe is unique and independent, many tribes share a common history of colonization and a connection to the land—legally and culturally. The majority of tribal nations were removed from their traditional homelands and placed on reservations by the federal government. In doing so, the federal government established these reservations as a permanent home for the tribe. But that home is now threatened by climate change.

The article …

Institute Of Public Health Newsletter- Volume2, Issue4, Institute Of Public Health (Iph)

Institute of Public Health Newsletter (IPHNL) and Other Publications

No abstract provided.

Textual Rules In Criminal Statutes, Joshua Kleinfeld

University of Chicago Law Review

No abstract provided.

Adverse Effect Of Nitroxynil And Albendazole On Rabbits, Eman Elalfy, Azza Hassan, Magdy Amer

Mansoura Veterinary Medical Journal

Objective:The present study aims to investigate the possible adverse effects of the subcutaneous injection of nitroxynil and oral administration of albendazole in rabbits. Design:Randomized controlled experimental study. Animals: 18 New Zealand rabbits of 1.50 ± 0.5 kg body weight, were allocated randomly into three groups (n=6). Procedures: Group A served as control, the group B was treated with albendazole (20 mg /kg B. wt.) orally and the group C was treated with nitroxynil (10mg /kg B. wt.) subcutaneously. Blood samples were collected at 1st, 7th and 14th days post drugs administration for hematological and biochemical determination. In addition, histopathological examination …

Apoε4 Lowers Energy Expenditure In Females And Impairs Glucose Oxidation By Increasing Flux Through Aerobic Glycolysis, Brandon C. Farmer, Holden C. Williams, Nicholas A. Devanney, Margaret A. Piron, Grant K. Nation, David J. Carter, Adeline E. Walsh, Rebika Khanal, Lyndsay E. A. Young, Jude Kluemper, Gabriela Hernandez, Elizabeth J. Allenger, Rachel Mooney, Lesley R. Golden, Cathryn T. Smith, J. Anthony Brandon, Vedant A. Gupta, Philip A. Kern, Matthew S. Gentry, Josh M. Morganti, Ramon C. Sun, Lance A. Johnson

Clinical and Translational Science Faculty Publications

Background: Cerebral glucose hypometabolism is consistently observed in individuals with Alzheimer’s disease (AD), as well as in young cognitively normal carriers of the Ε4 allele of Apolipoprotein E (APOE), the strongest genetic predictor of late-onset AD. While this clinical feature has been described for over two decades, the mechanism underlying these changes in cerebral glucose metabolism remains a critical knowledge gap in the field.

Methods: Here, we undertook a multi-omic approach by combining single-cell RNA sequencing (scRNAseq) and stable isotope resolved metabolomics (SIRM) to define a metabolic rewiring across astrocytes, brain tissue, mice, and human subjects expressing APOE4.

Reproductive Success Of Captive-Reared Allegheny Woodrats (Neotoma Magister) Released Into Genetically Depauperate Populations, Miracle M. Davis, Timothy J. Smyser, Scott A. Johnson, Joseph Duchamp, Jeffery L. Larkin, Robert K. Swihart, Jacqueline M. Doyle

United States Department of Agriculture Wildlife Services: Staff Publications

Habitat fragmentation and degradation have led to a proliferation of small and isolated populations that are vulnerable to genetic erosion. Reduction in habitat and concomitant declines in population connectivity can expediate the collapse of species that exist as natural metapopulations. In recent years, Allegheny woodrats (Neotoma magister) have experienced local extirpations and declines in genetic diversity across their range due to disease-related mortality, reduced food availability, and disruption of connectivity among subpopulations. In response, we developed a captive-breeding program to facilitate genetic management of isolated woodrat populations in Indiana. Between 2010 and 2012, 27 captive-reared individuals were released to four …

Charting A New Frontier Integrating Mathematical Modeling In Complex Biological Systems From Molecules To Ecosystems, Katharine A. White, Kira D. Mcentire, Nicole R. Buan, Lecia Robinson, Elisar Barbar

Department of Biochemistry: Faculty Publications

Advances in quantitative biology data collection and analysis across scales (molecular, cellular, organismal, and ecological) have transformed how we understand, categorize, and predict complex biological systems. This surge of quantitative data creates an opportunity to apply, develop, and evaluate mathematical models of biological systems and explore novel methods of analysis. Simultaneously, thanks to increased computational power, mathematicians, engineers, and physical scientists have developed sophisticated models of biological systems at different scales. Novel modeling schemes can offer deeper understanding of principles in biology, but there is still a disconnect between modeling and experimental biology that limits our ability to fully realize …

Storm: An Exploration Of Home Through Painterly Animation, Kirstin Hardin

Electronic Theses and Dissertations, 2020-2023

Storm is an animated short film that follows a family of Florida Sandhill Cranes. The family experiences a storm that destroys their nest and separates them from their smallest chick. The reunion of the cranes, at the end of the film, symbolizes that the sense of home consists of the members of the family, and not the physical place. The film combines digital two-dimensional (2D) animation with traditional paint on glass animation to create visual contrast between the cranes and the storm. The stylistic choices that I have made include showcasing paint strokes, going with a lineless and painterly animation …

Optimal Feature Learning For Facial Expression Recognition, Kamran Ali

Electronic Theses and Dissertations, 2020-2023

A great deal of research has been done to improve the performance of Facial Expression Recognition (FER) algorithms, but extracting optimal features to represent expressions remains a challenging task. The biggest drawback is that most work on FER ignores the inter-subject variations in facial attributes of individuals present in data. Hence, the representation extracted for the recognition of expressions is polluted by identity-related features that negatively affect the generalization capability of a FER technique on unseen identities. To overcome the effect of subject-identity bias, previous research shows the effectiveness of extracting identity-invariant expression features for FER. However, most of those …

Band Of Hope: How The Voice Of The People In John Wesley’S Classes And Bands Informs Today’S Church, Eddie Kirby

Doctor of Ministry Projects and Theses

Is there Hope for a diminishing Church? In the context of 18th century Anglican decline, John Wesley’s Methodists saw great growth. Wesley’s contemporaries say it was his attention to spiritual growth in the context of classes and bands that caused sustained increase in the society. But what do the people that made up the classes and bands say drew them in? This paper gives voice to these people. Letters of people within the classes and bands are analyzed to find what drew out their spiritual passion. Modern institutions that are successfully tapping into these stated needs are then analyzed to …

Autonomous Corporate Personhood, Carla L. Reyes

Washington Law Review

Several states have recently changed their business organization law to accommodate autonomous businesses—businesses operated entirely through computer code. A variety of international civil society groups are also actively developing new frameworks— and a model law—for enabling decentralized, autonomous businesses to achieve a corporate or corporate-like status that bestows legal personhood. Meanwhile, various jurisdictions, including the European Union, have considered whether and to what extent artificial intelligence (AI) more broadly should be endowed with personhood to respond to AI’s increasing presence in society. Despite the fairly obvious overlap between the two sets of inquiries, the legal and policy discussions between the …

Journal Of Food Law & Policy - Fall 2021, Journal Editors

Journal of Food Law & Policy

No abstract provided.

Of Single Nucleotides And Single Cells: Charting The Genotype-Phenotype Map At High Resolution Using Drosophila Melanogaster, Sneha Shreekant Mokashi

All Dissertations

Understanding the mechanisms by which genetic variation brings about phenotypic variation is essential for understanding variation in complex traits. Drosophila melanogaster is a powerful model organism for such studies. Flies are easy to raise in the laboratory under controlled genetic and environmental conditions and many genetic tools are widely available. To chart the genotype-phenotype map, we need to study how individual genetic variants contribute to phenotypic variation, as well as how environmental perturbations influence gene expression.

Regarding the former, I generated single nucleotide substitutions in Obp56h in a common genetic background. Obp56h, a member of the Odorant binding protein …

Deep Learning-Guided Prediction Of Material’S Microstructures And Applications To Advanced Manufacturing, Jianan Tang

All Dissertations

Material microstructure prediction based on processing conditions is very useful in advanced manufacturing. Trial-and-error experiments are very time-consuming to exhaust numerous combinations of processing parameters and characterize the resulting microstructures. To accelerate process development and optimization, researchers have explored microstructure prediction methods, including physical-based modeling and feature-based machine learning. Nevertheless, they both have limitations. Physical-based modeling consumes too much computational power. And in feature-based machine learning, low-dimensional microstructural features are manually extracted to represent high-dimensional microstructures, which leads to information loss.

In this dissertation, a deep learning-guided microstructure prediction framework is established. It uses a conditional generative adversarial network (CGAN) …

Reflections On The Phoenician Alphabet: Property And Its Defense In The Origin And Order Of The Letters (Draft #3), Gerald Leonard Cohen

Arts, Languages and Philosophy Faculty Research & Creative Works

No abstract provided.

Tissue Engineering And The Effect Of Volumetric Muscle Loss On Muscle Performance, Alex Pemberton

Biomedical Engineering Undergraduate Honors Theses

Trauma, for so many people, creates life altering injuries. One of the major injuries that results from trauma is volumetric muscle loss (VML), which is the loss of muscle tissue that cannot be naturally regenerated and results in chronic loss of function. When a small amount of damage is done to a muscle, but the underlying extracellular matrix of the cell is still intact, the muscle can regenerate much of its volume and function. If the injury damages the extracellular matrix, the injury site is instead filled with scar tissue, which cannot regenerate muscle mass or function. Seen widely in …

Integrating Multiple Survey Techniques To Document A Shifting Bat Community In The Wake Of White-Nose Syndrome, D. Scott Reynolds, Kevin Shoemaker, Susi Von Oettingen, Stephen Najjar, Jacques P. Veilleux, Paul R. Moosman Jr

KIP Articles

The long-term study of bat communities often depends on a diverse set of sampling methodologies that are chosen based on the species or habitat management priorities of the research project. Integrating the data from a diverse set of methodologies (such as acoustic monitoring and mist net sampling) would improve our ability to characterize changes in community structure or composition over time, such as one would expect following an emergent infectious disease such as white-nose syndrome. We developed a Bayesian state-space model to integrate these disparate data into a common currency (relative abundance). We collected both acoustic monitoring and mist net …

Using Iphone Significant Location Data To Improve Air Pollution Exposure Estimation, Elizabeth Eastman

Electronic Theses and Dissertations, 2020-2023

An accurate estimation of human exposure to ambient air pollution is crucial for air pollution health studies. Time-activity patterns may introduce substantial uncertainties in exposure estimation. As smartphones are becoming increasingly popular and their ownership is becoming ubiquitous in the US. Virtually all smartphones can collect location data, and such data is continuously somewhere. Therefore, it is clear that such stored location data has the potential to be used for characterizing an individual's time-activity patterns for air pollution health studies. However, studies on the accuracy and feasibility of using a smartphone's location data in air pollution exposure estimation are still …

Using Lidar To Locate Indigenous Mound Structures Along The St. Johns River In The Ocala National Forest, Taylor Collore

Electronic Theses and Dissertations, 2020-2023

The Indigenous people of Florida terraformed the region's relatively flat landscape into monumental vantage points for residence, burial, and displays of regional power. Known as mound structures today, these long-abandoned sites are now obscured by dense vegetation and thick tree canopies making their rediscovery difficult. Using Light Detection and Ranging (LiDAR) technology these lost sites can be located remotely for protection and study. In this research, LiDAR is used to locate Indigenous mound sites along the St. Johns River within the Ocala National Forest. Using free an open source geographic information systems (GIS) and similar software, LiDAR point cloud data …

Wavelet Particle Hydrodynamics For Less Smooth Flow, Oddny Brun

Electronic Theses and Dissertations, 2020-2023

The purpose of this research was to improve the smoothing operation in smoothed particle hydrodynamics, SPH, when the flow of matter is not smooth. Our main focuses are on the kernel selection, identifying the discontinuities in the sequences to be smoothed, and use of the Laplacian as opposed to artificial viscosity for improved physical accuracy. The results show that alternative kernels result in differences in how matter flows. These effects are explained by the kernels' gradient and Laplacian properties. Five alternative kernels were included in our analysis and our SPH-based simulation cases. Further, the sequences to be smoothed by the …

Communities Of Play And Practice: Collaborating With Audiences And Coworkers In Performative Online Spaces, Paul Oppold

Electronic Theses and Dissertations, 2020-2023

This study describes an ethnographic investigation of Communities of Play within Communities of Practice. As professional 'content creators', whose 'work' is 'play', are increasingly interacting with non-professional content consumers, whose 'play' is a kind of 'work', the barriers between 'work' and 'play' are increasingly dissolving. The purpose of this study was to examine the nature and frequency of the professionals' interactions with coworkers in an office and with the content consumers while working from home. Data were collected in the form of gameplay videos uploaded by the professional streamers from January of 2017 to March of 2018, downloaded by the …

December 1, 2021 Faculty Senate Minutes, University Of South Carolina

Faculty Senate

No abstract provided.

Criticizing Judges: A Lawyer's Professional Responsibility, Lonnie T. Brown

Georgia Law Review

Lawyers, as officers of the court, are expected to act with deference and respect toward judges. Speaking sharply to or publicly criticizing members of the bench is frowned upon and not infrequently met with punitive responses. The judiciary, however, is not above reproach. Judges are fallible and may possess personal biases, tainting self-interest, or even prejudice. As such, at times, they must disqualify themselves if their ability to dispense justice fairly and impartially can reasonably be questioned. Indeed, the very nature of a judge’s role requires avoidance of even the “appearance of impropriety.” When judges fail to adhere to this …

The Lost History Of Delegation At The Founding, Christine Chabot

Georgia Law Review

The new Supreme Court is poised to bring the administrative state to a grinding halt. Five Justices have endorsed Justice Gorsuch’s dissent in Gundy v. United States—an opinion that threatens to invalidate countless regulatory statutes in which Congress has delegated significant policymaking authority to the Executive Branch. Justice Gorsuch claimed that the “text and history” of the Constitution required the Court to replace a longstanding constitutional doctrine that permits broad delegations with a more restrictive one. But the supposedly originalist arguments advanced by Justice Gorsuch and like-minded scholars run counter to the understandings of delegation that prevailed in the Founding …

Local Weather Explains Annual Variation In Northern Goshawk Reproduction In The Northern Great Basin, Usa, Allyson B. Bangerter, Eliana R. Heiser, Jay D. Carlisle, Robert A. Miller

Intermountain Bird Observatory Publications and Presentations

Weather is thought to influence raptor reproduction through effects on prey availability, condition of adults, and survival of nests and young; however, there are few long-term studies of the effects of weather on raptor reproduction. We investigated the effects of weather on Northern Goshawk (Accipiter gentilis; henceforth goshawk) breeding rate, productivity, and fledging date in south-central Idaho and northern Utah, USA. Using data from 42 territories where we found evidence of breeding attempts in ≥1 yr from 2011–2019, we analyzed breeding rates using 315 territory–season combinations, analyzed productivity for 134 breeding attempts, and analyzed fledging date for 118 …

Boise State Magazine, Anna Webb (Editor)

FOCUS on Boise State

No abstract provided.

The Relationship Between Cognitive Functioning And Internalizing/Externalizing Behaviors In Children And Adolescents With Down Syndrome, Jessalin R. Good

USC Aiken Psychology Theses

Introduction: Down syndrome (DS) is a developmental disorder caused by a complete extra copy of chromosome 21. This genetic error results in a variety of other symptoms related to a range of medical and cognitive challenges. Although it has been reported that a significant relationship exists between cognitive functioning and both internalizing and externalizing behaviors in typically developing (TD) individuals, the literature is severely limited in investigating this relationship in those with DS.

Rationale: Internalizing and externalizing behaviors have been shown to have a negative relationship with cognitive functioning in TD children and adolescents (Shankman et al., 2010; Wood et …

Why Science Is Important To Us All: Identity And Environment, Anita K. Foeman

Sustainability Research & Practice Seminar Presentations

Professor Anita Foeman, Communication and Media - Why Science is Important to Us All: Identity and Environment