Digital Commons Network^™

Complete Chemical Structures Of Human Mitochondrial Trnas, Takeo Suzuki, Yuka Yashiro, Ittoku Kikuchi, Yuma Ishigami, Hironori Saito, Ikuya Matsuzawa, Shunpei Okada, Mari Mito, Shintaro Iwasaki, Ding Ma, Xuewei Zhao, Kana Asano, Huan Lin, Yohei Kirino, Yuriko Sakaguchi, Tsutomu Suzuki

Computational Medicine Center Faculty Papers

Mitochondria generate most cellular energy via oxidative phosphorylation. Twenty-two species of mitochondrial (mt-)tRNAs encoded in mtDNA translate essential subunits of the respiratory chain complexes. mt-tRNAs contain post-transcriptional modifications introduced by nuclear-encoded tRNA-modifying enzymes. They are required for deciphering genetic code accurately, as well as stabilizing tRNA. Loss of tRNA modifications frequently results in severe pathological consequences. Here, we perform a comprehensive analysis of post-transcriptional modifications of all human mt-tRNAs, including 14 previously-uncharacterized species. In total, we find 18 kinds of RNA modifications at 137 positions (8.7% in 1575 nucleobases) in 22 species of human mt-tRNAs. An up-to-date list of 34 …

Image Processing And Classification Of Remotely-Sensed Satellite Imagery: An Application Towards Cloud Detection, Oluwamuyiwa Adesola Adeegbe

Theses and Dissertations

Atmospheric studies have been carried out for decades to forecast weather and climate trends such as tropical storms, etc. Of recent concern is the level of greenhouse gases in the atmosphere, which has a relative influence on the weather and climate trends. Over the years, large weather satellites like the GOES series have been used to monitor these GHGs. However, an in-depth understanding of the movement of these gases requires consistent monitoring, which has given rise to the need for miniaturized satellites. Since the miniaturized satellites are novel, they require a ground-truth like the GOES-16 satellite to validate these observations. …

Parental Influences On Late Adolescents' Autonomous Motivation And Sexual Risk Knowledge And Behavior, Bettina Hornbuckle Riley

Dissertations

Adolescent risky sexual behavior is associated with unprotected sex, unplanned pregnancy, abortion, and contraction of sexually transmitted diseases (STDs) such as chlamydia, syphilis, gonorrhea, and HIV/AIDS. During their time of transition to adulthood, late adolescents make decisions about their sexual health that may or may not be motivated by parental (mother and father) sexual risk communication and autonomy support. While the adolescent may be physically independent or semi-independent from his/her parents, parents continue to influence their adolescents through past and present endorsement of certain behaviors. This research examined how parent-sexual risk communication and parental autonomy support may individually and collectively …

Relationship Between Nurses' Management Of Pediatric Oncology Patients' Symptoms And Job Satisfaction, Jennifer Isabelle Rheingans

Dissertations

A primary function of the pediatric oncology nurse is to provide symptom management to children with cancer. Symptom management strategies have been published, but there is scarce literature examining neither the actual use of these nursing interventions, nor the effects of using these interventions on the nurses' perceived work environment. The purpose of this study was to examine the nursing interventions used in treating pediatric oncology patients' symptoms, as well as the emotional sequelae from providing this care. Phase One of this study examined the content validity of the newly developed Nurses Distress and Interventions for Symptoms Survey (NDISS) utilizing …

Therapeutic Assessment With Couples: An Intervention To Enhance Healthy Relational And Marital Practices, Alexis C. Kenny

Dissertations, 2020-current

This dissertation details the creation and implementation of a new model of psychological assessment with partnered dyads, Therapeutic Assessment with Couples (TAC). As research continues to document the link between individual and relational/marital well-being (Jaremka, Glaser, Malarkey, & Kiecolt-Glaser, 2013; Kiecolt-Glaser & Newton, 2001; Sollenberger, et al., 2013), the cultivation of healthy practices from an interpersonal, romantic context becomes ever more crucial. Reviews of the shifting landscape of love and marriage in the U.S. are offered, along with compelling data concerning both the positive and negative implications associated with processes of partnering as well as relevant literature concerning Collaborative / …

Social Functioning In Subclinical Poor-Me And Bad-Me Paranoia, Thomas Bart

Psychology and Counseling Theses

Trower and Chadwick (1995) proposed paranoia as two distinct subtypes: poor-me – defined by strong beliefs of undeserved persecution, and bad-me – defined by strong beliefs of deserved punishment. Social functioning deficits are common in paranoia but have not been assessed within the poor-me and bad-me construct. Fourteen individuals with high levels of subclinical paranoia and 14 individuals with low levels of paranoia completed measures of depression, self-esteem, social functioning, and the emotional Stroop Task. Although there were no significant differences between the two paranoia subtypes on social functioning, a trend showed individuals with bad-me paranoia having more impaired social …

Contributions Of Fat And Carbohydrate Metabolism To Glucose Homeostasis In Childhood Change With Age And Puberty: A 12-Years Cohort Study (Earlybird 77), Ornella Cominetti, Joanne Hosking, Alison Jeffery, Jonathan Pinkney, Francois Pierre Martin

Peninsula Medical School

No abstract provided.

The Powerful Impact Of Role Models And Workshops On The Future Direction Of Females In Stem – Cit Campus Week Model, Mary Moloney, Norma Welch

Civil Engineering Research in Ireland 2020

The Faculty of Engineering and Science (FES) at Cork Institute of Technology (CIT) recognises the overwhelming evidence of a severe shortage in the uptake of female students of STEM courses and ultimately STEM careers. In its attempt to turn this tide, the faculty has pioneered a ‘female only’ campus week showcasing science, technology, engineering and maths (STEM) to TY students. This campus week commenced with a one-day event at CIT, in 2015 supporting the launch of the ‘I Wish’ initiative at Cork City Hall. The ‘I Wish’ (Initiative for women in STEM) is a not-for-profit group founded by three visionary …

Calamitous Pursuit: The Fetterman Fight, Marc C. Jeter

Bound Away: The Liberty Journal of History

Since that fateful December day in which Captain William Fetterman, two civilians, and 78 officers and men were annihilated in the present-day state of Wyoming, culpability has rested entirely with that officer. The oft- reason for this disastrous result is that Fetterman was effectively a reckless officer that dismissed out-of-hand the martial capabilities of warriors from the Sioux, Cheyenne, and Arapahoe tribes. This derogatory opinion therefore, led to his leading the task force placed under his command on December 21, 1866 into an ambush and wholescale death to every soldier and civilian.

The Politics Of Seeds And Their Effects On Small-Scale Paraguayan Farmers, Maeve Mallozzi-Kelly

Capstone Collection

International corporate seed companies have manipulated Paraguay’s politics and agricultural development since 1995, increasing Paraguay’s use and protection of genetically modified seeds, while also undermining farmers’ control over their production and financial stability by almost eliminating markets for heirloom varieties. Paraguay continues to be excluded from research critiquing the effects of neoliberal policies on global agricultural systems. Therefore, this study aims to illuminate small-scale farmers’ experiences and bring Paraguay into the global conversation on seed sovereignty by critically examining the effects Paraguay’s national seed policies have on small-scale farmer’s development opportunities and resilience to climate change. This question guides the …

Bibliometric Analysis Of Indian Optics Research: Identifying Knowledge Domain, Mallikarjun Kappi, B S Biradar Dr.

Library Philosophy and Practice (e-journal)

Optics is a significant research area both for its scientific importance and industrial solicitations. This study examines the optics research activities of India during 2015– 2019, based on the total publication output, its growth rate, quality of papers published and growth rate of India in the international perspective. Patterns of international collaborative research output and the major partner institutions of India are also deliberated. This study also evaluates the research performance of different types of Indian research institutions and the features of published literature in Indian and overseas journals. The data has been retrieved by using SCOPUS database. Total number …

The Indiana Statesman, August 27, 2020, Indiana State University

Student Newspaper

Graduation rates show success; Laura threatens coast with deadly storm; A life's work: Photographs by Fran Lattanzio; Schools can’t deny transgender students access to bathrooms

Aerosol Mass And Optical Properties, Smoke Influence On O3, And High No3 Production Rates In A Western U.S. City Impacted By Wildfires, Vanessa Selimovic, Robert J. Yokelson, Gavin R. Mcmeeking, Sarah Coefield

Chemistry and Biochemistry Faculty Publications

Evaluating our understanding of smoke from wild and prescribed fires can benefit from downwind measurements that include inert tracers to test production and transport and reactive species to test chemical mechanisms. We characterized smoke from fires in coniferous forest fuels for >1,000 hr over two summers (2017 and 2018) at our Missoula, Montana, surface station and found a narrow range for key properties. ΔPM2.5/ΔCO was 0.1070 ± 0.0278 (g/g) or about half the age-independent ratios obtained at free troposphere elevations (0.2348 ± 0.0326). The average absorption Ångström exponent across both years was 1.84 ± 0.18, or about half the values …

Treatment Longevity And Changes In Surface Fuel Loads After Pinyon–Juniper Mastication, Samuel S. Wozniak, Eva K. Strand, Timothy R. Johnson, April Hulet, Bruce A. Roundy, Kert Young

Articles

In the Intermountain West, land managers masticate pinyon pine (Pinus spp.) and juniper (Juniperus spp.) trees that have encroached sagebrush steppe communities to reduce canopy fuels, alter potential fire behavior, and promote growth of understory grasses, forbs, and shrubs. At three study sites in Utah, 45 sampling plots spanning a range of tree cover from 5% to 50% were masticated. We measured surface fuel load components three times over a 10‐yr period. We also measured tree cover, density, and height as indicators of treatment longevity. Changes in these variables were analyzed across the range of pre‐treatment tree cover …

Shadowed Image Particle Profiling Evaluation Recorder (Sipper) Plankton And Marine Snow Abundance And Distribution Data Collected Aboard Multiple Research Cruises In The Northeastern Gulf Of Mexico From 2010-05-12 To 2010-09-16, Kendra L. Daly, Andrew W. Remsen, Kurt Kramer

C-IMAGE data

This dataset contains the abundance and distribution of marine snow, phytoplankton, zooplankton, and larval fish, along with environmental parameters, collected aboard several research vessels (RV Weatherbird II, MV Specialty Diver, RV Gordon Gunter) in the northeastern Gulf of Mexico from 2010-05-12 to 2010-09-16. A high speed Dalsa Piranha-2 line-scan camera and a pseudo-collimated LED generated light sheet was used to image the shadows and outlines of resolvable particles that passed through a 100 cm2 field of view. The operational optical resolution of the system was ~65 um. The camera was towed at speeds between 2-3 knots in an oblique profile …

Tania Brown Gains Valuable Experience Through Undergraduate Research, Office Of University Communications

Gardner-Webb NewsCenter Archive

For her Undergraduate Research Scholar Project, Gardner-Webb University student Tania Brown, of Gastonia, N.C., studied an idea with a practical application. A biology major with a concentration in biomedical sciences, Brown tested the efficiency of using watermelon and cantaloupe peels to remove Bromothymol Blue from water. Bromothymol Blue is a dye used as an indicator in determining pH. It is yellow in acidic solutions, blue in basic solutions and green in neutral solutions, but is harmful to the respiratory tract and digestive system if swallowed.

Epigenetic Mechanisms Underlying Adult Post Stroke Neurogenesis, Xianshuang Liu, Baoyan Fan, Michael Chopp, Zhenggang Zhang

Neurology Articles

Stroke remains the leading cause of adult disability. Post-stroke neurogenesis contributes to functional recovery. As an intrinsic neurorestorative process, it is important to elucidate the molecular mechanism underlying stroke-induced neurogenesis and to develop therapies designed specifically to augment neurogenesis. Epigenetic mechanisms include DNA methylation, histone modification and its mediation by microRNAs and long-non-coding RNAs. In this review, we highlight how epigenetic factors including DNA methylation, histone modification, microRNAs and long-non-coding RNAs mediate stroke-induced neurogenesis including neural stem cell self-renewal and cell fate determination. We also summarize therapies targeting these mechanisms in the treatment of stroke.

Bioprinted In Vitro Model Of Human Glioblastoma, Rachel Lauren Schwartz

Theses and Dissertations

Glioblastoma multiform (GBM) is one of the most aggressive forms of primary brain tumors. GBM is fast progressing and resistant to treatment, resulting in a low survival rate. Conventional 2-dimensional tissue culture models cannot fully replicate the complexities of cancer lesions that contain multiple cell types and structures (e.g. vessels composed of endothelial cells, cancer cells, normal cells, etc.) as well as an intricate scaffold of proteins comprising the extracellular matrix (ECM). In addition, animal models cannot translate into the clinical disease in patients. Thus, this study has developed a bioprintable organ-on-a-chip (OOAC) model that mimics the important ECM factors …

Exploring The Association Of Academic Psychological Capital And Experiential Learning With Academic Performance, Diane Kutz

USF Tampa Graduate Theses and Dissertations

This research study expands upon the body of research seeking to define the effect of Academic Psychological Capital (Academic PsyCap) and student Participation in Experiential Learning on one success measure of students, Academic Performance, as measured by grade point average (GPA). It also seeks to investigate the moderating effect of Experiential Learning on the relationship between Academic PsyCap and Academic Performance. The study argues that Social Cognitive Theory and Broaden and Build Theory supported a reciprocal relationship between Academic PsyCap and Participation in Experiential Learning Activities and the positive relationship between both constructs and Academic Performance.

The study was conducted …

Grandparent Caregiver Well-Being And Identity Development, Brittany Torelli

Counseling and Psychology Dissertations

This dissertation aims to understand the experience of grandparent caregivers in the United States, exploring well-being and identity development as grandparents navigate their roles, both familiar and different at the same time. The investigation of well-being and identity development as they intersect and interact is crucial to understanding the complex and multilayered shifts this population faces as they transition into different roles. Grandparent caregivers experience impacts to their emotional well-being, physical health and financial status while simultaneously experiencing an impact to their identity development, carrying with it unique challenges.

This narrative inquiry obtains rich narratives from 9 participants, recruited from …

An Examination Of Hiv Risk, Testing And Prevention Intervention Participation Among Vulnerable Youth, Bianca V. Lopez

Dissertations and Theses

Background: Young gay, bisexual and other men who have sex with men (YGBM) of color are disproportionately affected by HIV and bear the burden of the disease in the United States. Gay and bisexual men – referred to in surveillance systems as men who have sex with men (MSM) – continue to be the risk group most severely affected by HIV in the United States. The dissertation study explored factors related on HIV prevention intervention participation, HIV testing and sexual risk behaviors among YGBM ages 13-29 in the Bronx. Additionally, this dissertation endeavored to study the concept of “intervention fatigue”, …

Exploring The Ethical Issues In Research Using Digital Data Collection Strategies With Minors: A Scoping Review, Danica Facca, Maxwell J. Smith, Jacob Shelley, Daniel Lizotte, Lorie Donelle Phd, Rn, Fcan

Publications

While emerging digital health technologies offer researchers new avenues to collect real-time data, little is known about current ethical dimensions, considerations, and challenges that are associated with conducting digital data collection in research with minors. As such, this paper reports the findings of a scoping review which explored existing literature to canvass current ethical issues that arise when using digital data collection in research with minors. Scholarly literature was searched using electronic academic databases for articles that provided explicit ethical analysis or presented empirical research that directly addressed ethical issues related to digital data collection used in research with minors. …

Genetic And Environmental Indicators Of Climate Change Vulnerability For Desert Bighorn Sheep, Tyler G. Creech, Clinton W. Epps, John D. Wehausen, Rachel S. Crowhurst, Jef R. Jaeger, Kathleen Longshore, Brandon Holton, William B. Sloan, Ryan J. Monello

Life Sciences Faculty Research

Assessments of organisms’ vulnerability to potential climatic shifts are increasingly common. Such assessments are often conducted at the species level and focused primarily on the magnitude of anticipated climate change (i.e., climate exposure). However, wildlife management would benefit from population-level assessments that also incorporate measures of local or regional potential for organismal adaptation to change. Estimates of genetic diversity, gene flow, and landscape connectivity can address this need and complement climate exposure estimates to establish management priorities at broad to local scales. We provide an example of this holistic approach for desert bighorn sheep (Ovis canadensis nelsoni) within and surrounding …

Analysis Of Genomic Sequence Data Reveals The Origin And Evolutionary Separation Of Hawaiian Hoary Bat Populations, Corinna A. Pinzari, Lin Kang, Pawel Michalak, Lars S. Jermiin, Donald K. Price, Frank J. Bonaccorso

Life Sciences Faculty Research

We examine the genetic history and population status of Hawaiian hoary bats (Lasiurus semotus), the most isolated bats on Earth, and their relationship to northern hoary bats (Lasiurus cinereus), through whole-genome analysis of single-nucleotide polymorphisms mapped to a de novo-assembled reference genome. Profiles of genomic diversity and divergence indicate that Hawaiian hoary bats are distinct from northern hoary bats, and form a monophyletic group, indicating a single ancestral colonization event 1.34 Ma, followed by substantial divergence between islands beginning 0.51 Ma. Phylogenetic analysis indicates Maui is central to the radiation across the archipelago, with the southward expansion to Hawai‘i and …

High Burden Of Self-Reported Sexually Transmitted Infections Among Key Populations In Mozambique: The Urgent Need For An Integrated Surveillance System, Makini A. S. Boothe, Charlotte Comé, Cynthia Semá Baltazar, Noela Chicuecue, Jessica Seleme, Denise Chitsondzo Langa, Isabel Sathane, Henry F. Raymond, Erika Fazito, Marleen Temmerman, Stanley Luchters

Obstetrics and Gynaecology, East Africa

Background: Key populations - men who have sex with men (MSM), female sex workers (FSW) and people who inject drugs (PWID) - are at high risk for sexually transmitted infections (STI) given their sexual risk behaviours along with social, legal and structural barriers to prevention, care and treatment services. The purpose of this secondary analysis is to assess the prevalence of self-reported STIs and to describe associated risk factors among participations of the first Biological Behavioural Surveillance (BBS) in Mozambique.

Methods: Responses from the first BBS surveys conducted in 2011-2014 were aggregated across survey-cities to produce pooled estimates …

Degree Recital: "When You Were Here" Joanna Deonarine, Andrews University

Student Degree Recitals 2019-2020

Joanna Deonarine, contralto, presents her senior recital "When You Were Here" accompanied by Ivan Rachath, piano. Works by Mozart, von Gluck, Thomas, and others.

Closing The Gap Between Mammalian And Invertebrate Peripheral Nerve Injury: Protocol For A Novel Nerve Repair, Maxwell Vest Md, Addison Guida Bsc, Cory Colombini Bsc, Kristina Cordes Bsc, Diana Pena Bsc, Marwa Maki Bsc, Michael Briones Bsc, Sabrina Antonio Bsc, Carmen Hollifield Bsc, Elli Tian Bsc, Lucas James Bsc, Christian Borashan Bsc, Johnnie Woodson Bsc, John Rovig Bsc, Hanaa Shihadeh Bsc, Alexander Karabachev Bsc, John Brosious Md, Ashley Pistorio Md

School of Medicine Faculty Research

Background: Outcomes after peripheral nerve injuries are poor despite current nerve repair techniques. Currently, there is no conclusive evidence that mammalian axons are capable of spontaneous fusion after transection. Notably, certain invertebrate species are able to auto-fuse after transection. Although mammalian axonal auto-fusion has not been observed experimentally, no mammalian study to date has demonstrated regenerating axolemmal membranes contacting intact distal segment axolemmal membranes to determine whether mammalian peripheral nerve axons have the intrinsic mechanisms necessary to auto-fuse after transection.Objective: This study aims to assess fusion competence between regenerating axons and intact distal segment axons by enhancing axon regeneration, delaying …

The Impact Of Knowledge Governance Mechanisms On Supply Chain Performance: Empirical Evidence From The Agri-Food Industry, Guoqing Zhao, Shaofeng Liu, H Chen, Dulekha Kasturiratne

Plymouth Business School

No abstract provided.

An Investigation Of Antenna, Ligand Side-Chain, And Metal Ion Effects On The Optical And Mri Properties Of Bimodal Lanthanide (Iii) Complexes, Marisa Poveda

Master's Theses

Magnetic Resonance Imaging (MRI) is a leading anatomical imaging modality for disease diagnosis. With the aid of Gd³⁺ based contrast agents, high resolution images of biological structures can be obtained. However, there is an increased need for contrast agents that are responsive to specific analytes and chemical environments. Paramagnetic Chemical Exchange Saturation Transfer (PARACEST) agents that utilize a paramagnetic lanthanide ion chelated with a ligand have shown great promise in this area. Lanthanide ions also possess luminescence properties that do not suffer from common limitations of conventional optical imaging agents such as autofluorescence and photobleaching. The projects described in …

The George-Anne Inkwell Edition, Georgia Southern University

The Inkwell

No abstract provided.