Digital Commons Network^™

Association Between Circulating Osteocalcin And Cardiometabolic Risk Factors Following A 4-Week Leafy Green Vitamin K-Rich Diet, Alexander Tacey, Marc Sim, Cassandra Smith, Mary N. Woessner, Elizabeth Byrnes, Joshua R. Lewis, Tara Brennan-Speranza, Jonathan M. Hodgson, Lauren C. Blekkenhorst, Itamar Levinger

Research outputs 2014 to 2021

Background: Evidence suggests that lower serum undercarboxylated osteocalcin (ucOC) may be negatively associated with cardiometabolic health. We investigated whether individuals with a suppression of ucOC following an increase in dietary vitamin K1 exhibit a relative worsening of cardiometabolic risk factors.

Materials and Methods: Men (n = 20) and women (n = 10) aged 62 ± 10 years participated in a randomized, controlled, crossover study. The primary analysis involved using data obtained from participants following a high vitamin K1 diet (HK; 4-week intervention of increased leafy green vegetable intake). High and low responders were defined based on the median percent reduction …

Innovation And New Technologies In Spine Surgery, Circa 2020: A Fifty-Year Review., G. Bryan Cornwall, Andrea Davis, William R. Walsh, Ralph J. Mobbs, Alexander Vaccaro

Rothman Institute Papers

Spine surgery (lumbar, cervical, deformity, and entire spine) has increased in volume and improved in outcomes over the past 50 years because of innovations in surgical techniques and introduction of new technologies to improve patient care. Innovation is described as a process to add value or create change in an enterprise's economic or social potential. This mini review will assess two of three assessments of innovation in spine surgery: scientific publications and patents issued. The review of both scientific publications and issued patents is a unique assessment. The third assessment of innovation: regulatory clearances of medical devices and equipment for …

External Use Of Mirabilite Combined With Lactulose Improves Postoperative Gastrointestinal Mobility Among Older Patients Undergoing Abdominal Surgery, Wenyan Pan, Shining Cai, Jos M. Latour, Ming Zhong, Minzhi Lv, Jingjing Li, X Zhang, Y Zhang

School of Nursing and Midwifery

No abstract provided.

North American Forest Grouse Harvest Regulations, Melissa Chelak, Justin Small, David K. Dahlgren

All Current Publications

This bulletin reviews North American forest grouse harvest regulations. Forest grouse are a highly sought-after wildlife resource across North America, both for their intrinsic value and as game species. Their unique breeding displays and the habitat they rely on are part of North America’s incredible natural heritage. Most forested landscapes in the upper latitudes of North America have the potential to provide habitat for one or more forest grouse species. This includes a large variety of vegetation types including the aspen forests of the upper Midwest, the coniferous boreal forest of Canada, the Pacific coastal rain forests that extend from …

Lower Predation With Increasing Altitude In The Mesquite Lizard Sceloporus Grammicus, Miguel A. Domínguez-Godoy, J. Erick Gómez-Campos, Robyn Hudson, Aníbal H. Díaz De La Vega-Pérez

Western North American Naturalist

We evaluated differential predation pressure on the lizard Sceloporus grammicus at 3 sampling sites along a high-mountain gradient, using 3 methods of assessment: attacks on plasticine lizard models, frequency of lizard tail autotomy, and estimation of the richness of potential predators. We placed a total of 720 lizard models at each sampling site (2600, 3100, and 4150 m asl) on 6 d during the reproductive season and on 6 d during the nonreproductive season. Each day we placed 60 models (n = 30 for each sex, with each sex having 10 each of 3 gular color morphotypes [gray, yellow, …

The Effect Of Palm Cooling Device Core Control (Ava) On Some Physiological Recovery Responses Among Swimmers, Noor Issa, Amal Al-Hamad

An-Najah University Journal for Research - B (Humanities)

The main purpose of this study is to determine the effect of hand cooling recovery device Core Control (AVA) on physiological variables, blood lactate (LA), creatin phosphokinase (CPK), lactate dehydrogenize (LDH), in 200m free style swim. Method of the Study: Seven well-trained swimmers, volunteer to participate in the study weight (72.93±11.10kg) age (16yr), height (1.75±0.5 M). The present experiment consisted of two protocols separated by 48 h Protocol (1) Baseline values (b) blood samples were collected, Subjects performed a (10) min freestyle warming up, followed with 200m freestyle sprint test, then passive recovery (PR) for (30) min. After the passive …

Modeling Biotic & Abiotic Drivers Affecting Biogeomorphic Coastal Foredunes, Bianca Charbonneau

Sustainability Seminar Series

Coastal dunes are exceptionally dynamic terrestrial habitats that will only grow increasingly vulnerable with climate change. A structured approach to protect and restore these and other coastal biogeomorphic interface habitats is needed to maintain their invaluable ecosystem services. Vegetation in these habitats acts as ecosystem engineers such that, to achieve this, one must understand and accurately forecast vegetation dynamics at the nexus of shifting abiotic conditions and drivers of change. We developed a process-based model for coastal dune vegetation ecology, specifically, growth, density, and colonization as it affects and is affected by shifting habitat topography and storm event impact. The …

Florida Historical Quarterly, Volume 80, Number 1, Florida Historical Society

Florida Historical Quarterly

Religion on Florida's Territorial Frontiers Ernest F. Dibble
Fort Denaud: Logistics Hub of the Third Seminole War Jay Jennings
Green Awakening: Social Activism and the Evolution of Marjory Stoneman Douglas's Environmental Consciousness Jack E. Davis
Historic Notes and Documents: The Spanish Dedication Tablets from San Marcos de Apalache Ryan J. Wheeler and Henry A. Baker
Book Reviews
History News

Teaching While Autistic: Constructions Of Disability, Performativity, And Identity, Alexa Baird

Ought: The Journal of Autistic Culture

The structure of organizational contexts and practices tends to be based on the normative assumption of the non-disabled individual as the prototypical state of being human. Therefore, schools, like many institutional sites, act to replicate the normative expectation of ableism and the atypical mind. These parameters impact not only the disabled students that operate both within these educational spaces but also the disabled adults embedded within these arenas professionally. Thus, disabled teachers act as a marginalized group that has historically been largely absent from the discourse on education and critical disability studies. This paper seeks to develop an understanding of …

Neurodiversity And The Deep Structure Of Schools, Peter Smagorinsky

Ought: The Journal of Autistic Culture

No abstract provided.

Testimony In Support Of B23-0887, The "Expanding Student Access To Period Products Act Of 2020" Before The Committee Of The Whole And The Committee On Education, Marcy L. Karin, Galina M. Abdel Aziz

D.C. Council Testimony

No abstract provided.

Demystifying First-Time Mothers’ Postpartum Mental Health: A Phenomenological Study Of The Transition To Becoming A Mother, Megan Dooley Hussmann

Dissertations

Becoming a mother is a significant life event that can greatly impact maternal mental health. Understanding maternal mental health is an important interdisciplinary goal because it could lead to mother’s receiving better care and support from both mental health and medical professionals. Seven first-time mothers with a baby under the age of one were interviewed for a phenomenological qualitative study, which investigated first-time mothers’ postpartum mental health experiences. This study was guided by two research questions: How do new mothers experience their postpartum mental health in comparison to how they experienced their mental health before having their baby, and how …

Aerosol Jet Printed Capacitive Strain Gauge For Soft Structural Materials, Kiyo T. Fujimoto, Jennifer K. Watkins, Timothy Phero, Takoda Bingham, Kshama Lakshmi Ranganatha, Benjamin C. Johnson, Zhangxian Deng, Brian Jaques, David Estrada

Materials Science and Engineering Faculty Publications and Presentations

Soft structural textiles, or softgoods, are used within the space industry for inflatable habitats, parachutes and decelerator systems. Evaluating the safety and structural integrity of these systems occurs through structural health monitoring systems (SHM), which integrate non-invasive/non-destructive testing methods to detect, diagnose, and locate damage. Strain/load monitoring of these systems is limited while utilizing traditional strain gauges as these gauges are typically stiff, operate at low temperatures, and fail when subjected to high strain that is a result of high loading classifying them as unsuitable for SHM of soft structural textiles. For this work, a capacitance based strain gauge (CSG) …

Synthesis Of Phosphonomethyl Tetrahydrofurans And Phostones, Rishi Paudel

Dissertations

This work has been divided into two major projects:

1) Synthesis of phosphonomethyl tetrahydrofurans by using the Mori-Tamaru reaction: The Mori-Tamaru reaction of phosphonate-substituted dienes is unexplored, and the directing effects of the phosphono-group are uncertain. The objectives of this research are to develop the homoallylation of phosphonodienes with different aldehydes, followed by their cyclization to phosphonomethyl tetrahydrofuran ring systems through an oxa-Michael reaction. This method has also been applied for the synthesis of 3-hydroxy substituted phosphonomethyl tetrahydrofuran rings (9) which might lead to the synthesis of 2’deoxy C-nucleosides.

2) Synthesis of vinyl phosphonates and phostones: Synthetic …

Shrinking Salmon: Is Climate Change Linked To Animal Body Size?, Monica D. Bacchus

Scientific Communication News

No abstract provided.

Larry, Roland Karnatz

Longwood: Life during COVID-19

Photo of Wygal room 104. There is a biology class sharing our lecture room and a skeleton hung on its frame in the corner for weeks. The drum kit appeared part way through the semester and the opportunity was not to be missed! Cigarette supplied by a violinist. The "no smoking" sign, a remnant of a distant past, was a happy coincidence.

Model Organism Development And Evaluation For Late-Onset Alzheimer's Disease: Model-Ad., Adrian L Oblak, Stefania Forner, Paul R Territo, Michael Sasner, Gregory W. Carter, Gareth R Howell, Stacey J Sukoff-Rizzo, Benjamin A Logsdon, Lara M Mangravite, Ali Mortazavi, David Baglietto-Vargas, Kim N Green, Grant R Macgregor, Marcelo A Wood, Andrea J Tenner, Frank M Laferla, Bruce T Lamb, The Model-Ad Consortium

Faculty Research 2020

Alzheimer's disease (AD) is a major cause of dementia, disability, and death in the elderly. Despite recent advances in our understanding of the basic biological mechanisms underlying AD, we do not know how to prevent it, nor do we have an approved disease-modifying intervention. Both are essential to slow or stop the growth in dementia prevalence. While our current animal models of AD have provided novel insights into AD disease mechanisms, thus far, they have not been successfully used to predict the effectiveness of therapies that have moved into AD clinical trials. The Model Organism Development and Evaluation for Late-onset …

Interactions Of The Nlrp3 Inflammasome Complex, Nyasha Makoni

Dissertations

The innate immune system is the first line of defense in response to invasion by pathogens. One of the major pathways in the innate immune system involves a three-protein complex known as the NLRP3 inflammasome. This complex comprises of NLRP3, ASC, and procaspase-1. In response to stimuli, the inflammasome assembles to activate caspase-1 which subsequently facilitates production of interleukin-1β (IL-1β), an inflammatory cytokine. The NLRP3 inflammasome has been implicated in a variety of inflammatory disorders including Alzheimer’s disease (AD). Amyloid beta (Aβ) is the protein that causes AD and Aβ deposits in the brain activate microglia resulting in chronic inflammation. …

Orda Weekly Update, 2020.11.23, Office Of Research And Development Administration

ORDA Weekly Update

No abstract provided.

A Primary Human T-Cell Spectral Library To Facilitate Large Scale Quantitative T-Cell Proteomics., Harshi Weerakoon, Jeremy Potriquet, Alok K Shah, Sarah Reed, Buddhika Jayakody, Charu Kapil, Mukul K Midha, Robert L Moritz, Ailin Lepletier, Jason Mulvenna, John J Miles, Michelle M Hill

Articles, Abstracts, and Reports

Data independent analysis (DIA) exemplified by sequential window acquisition of all theoretical mass spectra (SWATH-MS) provides robust quantitative proteomics data, but the lack of a public primary human T-cell spectral library is a current resource gap. Here, we report the generation of a high-quality spectral library containing data for 4,833 distinct proteins from human T-cells across genetically unrelated donors, covering ~24% proteins of the UniProt/SwissProt reviewed human proteome. SWATH-MS analysis of 18 primary T-cell samples using the new human T-cell spectral library reliably identified and quantified 2,850 proteins at 1% false discovery rate (FDR). In comparison, the larger Pan-human spectral …

Proteasome-Mediated Regulation Of Cdhr1a By Siah1 Modulates Photoreceptor Development And Survival In Zebrafish, Warlen P. Piedade, Kayla F. Titialii-Torres, Ann C. Morris, Jakub K. Famulski

Biology Faculty Publications

Congenital retinal dystrophies are a major cause of unpreventable and incurable blindness worldwide. Mutations in CDHR1, a retina specific cadherin, are associated with cone-rod dystrophy. The ubiquitin proteasome system (UPS) is responsible for mediating orderly and precise targeting of protein degradation to maintain biological homeostasis and coordinate proper development, including retinal development. Recently, our lab uncovered that the seven in absentia (Siah) family of E3 ubiquitin ligases play a role in optic fissure fusion and identified Cdhr1a as a potential target of Siah. Using two-color whole mount in situ hybridization and immunohistochemistry, we detected siah1 and cdhr1a co-expression as well …

Developing Nuclear Security Culture At Academic And Educational Institutions, Mostafa Kofi, Lamiaa Fiala, May Al-Muammar, Zenobia S. Homan

International Journal of Nuclear Security

In recent years, the use of radioactive and nuclear sources for diagnosis and treatment has become more widespread in the medical field. These sources are present in universities, university hospitals, and academic institutions, making it necessary to develop a strong nuclear security culture among academics. There are many widespread and complex challenges to improving security culture, often from scratch. The research solution presented in this paper is how to develop a strong and sustainable nuclear security culture among academics. Workplaces are often culturally diverse, so it can be challenging to achieve a common belief in nuclear security and an institutional …

[Silk Snapper, Lutjanus Vivanus] Neurocranium, Rachel Taylor, David W. Kerstetter

All Scans: Kerstetter Fisheries and Avian Ecology 3D Scan Series

Silk snapper, Lutjanus vivanus, apart of the Lutjanidae family. A species of red snapper commonly found in the Atlantic and Gulf of Mexico.

Neurocranium prep submission for Dr. Kertstetter, MBIO 3700 Biology of Fishes

Biologists Developing Mobile App For Coastal Marine Assessment, Edwin B. Smith

University of Mississippi News

Glenn Parsons and Richard Buchholz lead new Gulf of Mexico Citizen Scientist Initiative

Autonomy And Precautions In The Law Of Armed Conflict, Eric Talbot Jensen

International Law Studies

Already a controversial topic, legal debate and broader discussions concerning the amount of human control required in the employment of autonomous weapons—including autonomous cyber capabilities—continues. These discussions, particularly those taking place among States that are Parties to the 1980 Certain Conventional Weapons Convention, reveal a complete lack of consensus on the requirement of human control and serve to distract from the more important question with respect to autonomy in armed conflict: under what conditions could autonomous weapons “select” and “attack” targets in a manner that complies with the law of armed conflict (LOAC).

This article analyzes the specific LOAC rules …

Sleep Deprivation And Neurological Disorders, Muhammed Bishir

Brain and Mind Institute

Sleep plays an important role in maintaining neuronal circuitry, signalling and helps maintain overall health and wellbeing. Sleep deprivation (SD) disturbs the circadian physiology and exerts a negative impact on brain and behavioural functions. SD impairs the cellular clearance of misfolded neurotoxin proteins like α-synuclein, amyloid-β, and tau which are involved in major neurodegenerative diseases like Alzheimer’s disease and Parkinson’s disease. In addition, SD is also shown to affect the glymphatic system, a glial-dependent metabolic waste clearance pathway, causing accumulation of misfolded faulty proteins in synaptic compartments resulting in cognitive decline. Also, SD affects the immunological and …

An Investigation Into The Adverse Effects Of Oxidative Stress From Exposure To Bisphenol A And Its Analogues, Rachel Nas

Senior Honors Theses

Oxidative stress is a physiological event caused by an overaccumulation of reactive oxygen species (ROS) within the body. While ROS are a natural by-product of oxygen metabolism, too many can lead to cell and tissue damage and contribute to many etiologies. Bisphenol A (BPA), a component of many plastic products, has been shown to induce oxidative stress. While the industrial usage of BPA usage has lessened, the safety of its replacements is unknown. This paper will primarily discuss ROS and mechanisms of oxidative stress, the usage of BPA and its analogues, etiologies associated with oxidative stress resulting from exposure to …

[Excerpt From] The Peace Model For Evidence-Based Practice For Clinical Nurses, Reynaldo R. Rivera, Joyce J. Fitzpatrick

Sigma Publications: Book Excerpts

This item record pertains to an excerpt from The PEACE Model for Evidence-Based Practice for Clinical Nurses, which is provided free of charge by the publisher.

About this book: In The PEACE Model Evidence-Based Practice Guide for Clinical Nurses, authors Reynaldo R. Rivera and Joyce J. Fitzpatrick provide a road map to model implementation. Readers will learn to formulate and address clinical questions and disseminate findings, ultimately helping nurses integrate evidence at the bedside and through quality research.

Two New Species Of Tardigrada From Moss Cushions (Grimmia Sp.) In A Xerothermic Habitat In Northeast Tennessee (Usa, North America), With The First Identification Of Males In The Genus Viridiscus, Diane R. Nelson, Rebecca Adkins Fletcher, Roberto Guidetti, Milena Roszkowska, Daria Grobys, Lukasz Kaczmarek

ETSU Faculty Works

Background. The phylum Tardigrada consists of over 1,300 species that inhabit terrestrial, freshwater and marine environments throughout the world. In terrestrial habitats they live primarily in mosses, lichens, leaf litter and soil, whereas tardigrades in freshwater and marine environments are mainly found in sediments and on aquatic plants. More than 65 species have been previously reported in the state of Tennessee, USA. Methods. Tardigrades present in moss cushions (Grimmia sp.) collected from a xerothermic habitat on the East Tennessee State University campus, Johnson City, TN, USA, were extracted, mounted on slides, identified, and counted. Additional samples of fresh dried moss …

The Effects Of Passive Hallux Adduction On Posterior Tibial Artery Blood Flow Compared To The Lateral Plantar Artery, Jaysen Alani Hatch

Theses and Dissertations

Passive hallux adduction has been shown to decrease blood flow in the lateral plantar artery (LPA) in a non-weight-bearing condition. Further research in weight-bearing and shod conditions is necessary to explore relationships between altered blood flow and injury or tissue healing. However, measuring blood flow in a shod foot would require an alternate measurement location to accommodate footwear, such as the more proximal posterior tibial artery (PTA). PURPOSE: To determine changes in blood flow in the PTA and LPA subsequent to passive hallux adduction and to compare the observed changes between the two arteries. Second, to determine if measurement at …