Digital Commons Network^™

Innovator - Spring 2020

Innovator

05 - Message from the President

08 - The Past is a Prologue

15 - Shrinking World/Expanding Horizons

16 - The Nexus: News at Jefferson

20 - Jefferson Hits the Runway at NYFW

22 - A Game Changer

26 - Binge Swatching

30 - Breaking Down the Walls

38 - Coming Full Circle

44 - Question and Innovate

46 - Designer Health

50 - The Site is the Star

54 - Transcend and Include

60 - Reimagine

64 - Ram Roundup

68 - Class Notes

74 - In Memory

78 - Triva

Innovator - Winter 2020

Innovator

8 - A MESSAGE FROM THE PRESIDENT

10 - WHAT’S HAPPENING AT JEFFERSON

16 - DEFINING THE FUTURE OF LEARNING AND WORK
How well are institutions of higher education preparing their graduates for the realities of work in the 21st century?

26 - IT’S IN OUR DNA
Innovative partnership leads to Jefferson Institute for Bioprocessing.

32 - JEFFERSON IS GLOBAL
Jefferson’s study away program provides life-changing experiences for students.

36 - PURSUING KNOWLEDGE AND IMPACT
Provost Mark L. Tykocinski, MD, explores the different research initiatives happening across Jefferson.

38 - LIVING THE DREAM
Jefferson grad orbits among the stars like …

Innovator - Fall 2014

Innovator

4 - What’s Now: Impact Edition

6 - Scholarships

8 - Term Chairs

10 - Power to Innovate Campaign

20 - Donor Profile: Handsel Minyard

23 - Financial Information

Innovator - Summer 2011

Innovator

02 - LIVING IN YOUR GENES
Through its nationally ranked physician assistant studies program — led by insightful faculty and an award-winning champion of genetic literacy education — PhilaU is transforming a generation to “think genetically.”

06 - PRESIDENT SPINELLI COMMENTARY
New College structure maximizes students’ experiences

08 - QUIET ON THE SET
Emmy-nominated alumna Kim Wannop ’99 dresses six or more sets each week for Fox’s hit TV show Bones.

12 - MEET RON KANDER, PH.D.
The executive dean of the College of Design, Engineering and Commerce leads a revolutionary, transdisciplinary curriculum.

18 - NEWS

22 - PROFILES

24 …

Innovator - Fall 2010

Innovator

2 - TEXTILE LEGACY LEADING TO BIOMEDICAL BREAKTHROUGHS
PhilaU researchers developing a cardiac patch

6 - PRESIDENT SPINELLI COMMENTARY
A Great Return on Investment

8 - THE BUSINESS OF FASHION
Fashion thinking zeros in on bottom line

14 - MEN IN FLIGHT
Guggenheim Fellow chronicles history of male flight attendants

18 - PHILAU NEWS

22 - Q&A WITH NATHAN VANHOOK ’03
Alumnus designs new Nike shoe “Aina Chukka”

24 - PROFILES

28 - PHILAU AROUND THE WORLD
Alumni, faculty and students’ global impact

33 - AWARDS AND HONORS

34 - A THIRD DIMENSION TO THE INTERNATIONAL BUSINESS EXPERIENCE
Faculty commentary …

Innovator - Winter 2010

Innovator

2 - STEPPING FORWARD AS A NATIONAL MODEL
PhilaU takes a leadership role in green education

6 - 125 THINGS THAT MAKE PHILAU GREAT
Celebrating our 125th Anniversary

12 - PRESIDENT SPINELLI COMMENTARY
A Solid Foundation for the 21st Century

14 - NEW VISION FOR THE ACADEMY
A day in the life of Provost Randy Swearer

18 - STRATEGIC INITIATIVES
Developing the model for professional education in the 21st century

22 - PROFILES

24 - TRUSTEE UPDATE

26 - PHILAU NEWS

31 - AWARDS AND HONORS

32 - EMBRACING THE NEW WORLD OF PERSONALIZED MEDICINE
Faculty commentary by Michael A. …

The Vimentin Cytoskeleton: When Polymer Physics Meets Cell Biology, Alison E. Patteson, Robert J. Carroll, Daniel V. Iwamoto, Paul A. Janmey

Physics - All Scholarship

The proper functions of tissues depend on the ability of cells to withstand stress and maintain shape. Central to this process is the cytoskeleton, comprised of three polymeric networks: F-actin, microtubules, and intermediate filaments (IFs). IF proteins are among the most abundant cytoskeletal proteins in cells; yet they remain some of the least understood. Their structure and function deviate from those of their cytoskeletal partners, F-actin and microtubules. IF networks show a unique combination of extensibility, flexibility and toughness that confers mechanical resilience to the cell. Vimentin is an IF protein expressed in mesenchymal cells. This review highlights exciting new …

Revisiting The Trail Of Tears: Tribal Control And Environmental Justice., Rachel Robinson-Greene

Languages, Philosophy, and Communication Studies Faculty Publications

In early October 2020, the Trump administration’s Environmental Protection Agency sent a letter to Oklahoma governor Kevin Stitt. The letter granted Stitt environmental regulatory control over all of the tribal lands in the state. Among other things, this gives Stitt the power to determine whether hazardous waste can be dumped on tribal lands, the ability to make decisions regarding whether and where fracking can take place, and the ability to determine if and where large-scale industrial animal agriculture, with all its attendant pollution, can operate in tribal jurisdictions.

A Review Of The Nearctic Species Of Fornax Laporte (Coleoptera: Eucnemidae: Macraulacinae: Macraulacini) With Descriptions Of Six New Species, Robert L. Otto

Insecta Mundi

The Nearctic species of Fornax Laporte are reviewed. Three species are redescribed, and six new species are described mainly from southeastern United States. The new species are F. appalachiensis , F. con­vexicollis, F. floridana, F. lucidicollis, F. melsheimeri and F. parallelicollis. A neotype is designated for Hylochares bicolor Melsheimer, with notes on its purpose. Each species is diagnosed and imaged. A new identification key is provided for all known species of Fornax present in the Nearctic region, replacing previous Nearctic species keys of Muona (2000) and Otto (2017).

New Species Of Trachyderini From Mexico And Central America (Coleoptera: Cerambycidae: Cerambycinae), James E. Wappes, Antonio Santos-Silva

Insecta Mundi

Three new trachyderine species in the subtribe Trachyderina (Coleoptera: Cerambycidae: Ceram­bycinae: Trachyderini) are described: Entomosterna kovariki Wappes and Santos-Silva, new species, from Belize; Gortonia sumideroensis Wappes and Santos-Silva, new species, from Mexico (Chiapas); and Sphaeno­thecus vandenberghei Wappes and Santos-Silva, new species, from Nicaragua. A new key to Entomosterna species, and a previous Sphaenothecus key by Chemsak and Noguera (1998) is modified to include the new species, with both provided herein.

Redescripción De Eulachnesia Boteroi Monné Y Monné, 2015 (Coleoptera: Cerambycidae: Lamiinae: Hemilophini), Sergio Devesa

Insecta Mundi

Eulachnesia boteroi Monné y Monné, 2015 (Coleoptera: Cerambycidae: Lamiinae: Hemilophini) es redescrito, ilustrado dorsal, ventral y lateralmente, así como diversos detalles de su morfología. Es realizada la designación de un neotipo y la especie es registrada por primera vez para Ecuador. Adicionalmente, es propuesta una clave para la identificación de las especies del género.

Eulachnesia boteroi Monné and Monné, 2015 (Coleoptera: Cerambycidae: Lamiinae: Hemilophini) is redescribed and illustrated dorsally, ventrally and laterally, with several specific details. The designation of a neotype is made and the species is registered for the first time for Ecuador. Additionally, a key is proposed for …

Selenopidae (Arachnida: Araneae), A New Host Spider Family For The Spider Wasp Tachypompilus Ferrugineus (Say) (Hymenoptera: Pompilidae: Pompilini), Frank E. Kurczewski, Rick C. West, Sarah C. Crews, N. R. Jenzen-Jones

Insecta Mundi

Four online photographs from Oaxaca, Mexico taken by N. R. Jenzen-Jones and posted on inaturalist.org reveal Selenops sp., probably S. mexicanus Keyserling (Arachnida: Araneae: Selenopidae), as a new host spider species, genus and family for the common and widespread American spider wasp Tachypompilus fer­rugineus (Say) (rusty spider wasp). The wasp transported the immobilized spider up an exterior stucco wall of a house, dorsal side upward, walking backwards for 3 m to her nest in a gap between the wooden planking and stucco wall beneath the roof, while grasping the femur of its right pedipalp with her mandibles.

Addendum And Update To Zidek (2020):Catalogue Of Species-Group Names Assigned To Copris Geoffroy, Coptodactyla Burmeister, Litocopris Waterhouse, Microcopris Balthasar, Paracopris Balthasar, Pseudocopris Ferreira, Pseudopedaria Felsche, Sinocopris Ochi, Kon And Bai, And Thyregis Blackburn (Coleoptera: Scarabaeidae: Scarabaeinae: Coprini), Jiri Zidek

Insecta Mundi

The catalogue of species-group names of nine coprine genera (Coleoptera: Scarabaeidae: Scarabaeinae: Coprini), published earlier this year, is updated and revised. Presented are species-group taxa overlooked in compiling the catalogue and new species-group taxa described in 2020, i.e. after the cut-off date of the catalogue.

Validation Of Chrysina Valentini Zubov And Ivshin, 2019 (Coleoptera: Scarabaeidae: Rutelinae) By Morphometric And Cuticular Reflectance Analyses, David C. Robacker, Karen M. Robacker, William C. Warfield

Insecta Mundi

Micromorphometric analyses of genital capsules and comparison of adult cuticular reflectance of two species of Chrysina Kirby (Coleoptera: Scarabaeidae: Rutelinae) support the status of C. valentini Zubov and Ivshin, 2019 as a valid species. Compared with its closest relative C. optima (Bates, 1888), capsules of C. valentini are proportionately wider at the base of the parameres than those of C. optima, and taper toward the apex more abruptly. Reflectance of C. valentini under natural light appears slightly greenish while C. optima is uniformly reddish. The number of teeth on the protibia and the shape of the mesosternal process, characters …

A New Species Of Oncotophasma Rehn, 1904 (Phasmida: Diapheromeridae) From Colombia, Andres David Murcia, Oscar J. Cadena-Castañeda, Daniela Santos Martins Silva

Insecta Mundi

Abstract. Oncotophasma aurantiaviridiata Murcia, Cadena-Castañeda, and Silva new species (Phasmida: Diapheromeridae) from the Colombian Andes is described. The new species is distinguished by its peculiar coloration, which highlights greenish and orange tones. It is also the first record of the genus for the eastern slope of the Colombian Andes. The previous distribution recorded for the genus is the Chocó biogeographic region from Costa Rica to Colombia, with species being found in the Colombian areas of influence of this biogeographic region, such as the western and central slopes of the Andes.

Resumen. Se describe a Oncotophasma aurantiaviridiata Murcia, Cadena-Castañeda y …

Description Of The Male Of Euschistus (Euschistus) Baranowskii Eger And Bianchi (Heteroptera: Pentatomidae: Pentatominae: Carpocorini), Joseph E. Eger Jr.

Insecta Mundi

Euschistus (Euschistus) baranowskii Eger and Bianchi (Heteroptera: Pentatomidae: Pentatominae: Carpocorini) was described based on a single female specimen. In this paper, I describe the male of the spe­cies, primarily the genitalia, and compare it to other species of Euschistus (Euschistus) Dallas.

Predicting Breast Cancer Response To Neoadjuvant Treatment Using Multi-Feature Mri: Results From The I-Spy 2 Trial., Wen Li, David C Newitt, Jessica Gibbs, Lisa J Wilmes, Ella F Jones, Vignesh A Arasu, Fredrik Strand, Natsuko Onishi, Alex Anh-Tu Nguyen, John Kornak, Bonnie N Joe, Elissa R Price, Haydee Ojeda-Fournier, Mohammad Eghtedari, Kathryn W Zamora, Stefanie A Woodard, Heidi Umphrey, Wanda Bernreuter, Michael Nelson, An Ly Church, Patrick Bolan, Theresa Kuritza, Kathleen Ward, Kevin Morley, Dulcy Wolverton, Kelly Fountain, Dan Lopez-Paniagua, Lara Hardesty, Kathy Brandt, Elizabeth S Mcdonald, Mark Rosen, Despina Kontos, Hiroyuki Abe, Deepa Sheth, Erin P Crane, Charlotte Dillis, Pulin Sheth, Linda Hovanessian-Larsen, Dae Hee Bang, Bruce Porter, Karen Y Oh, Neda Jafarian, Alina Tudorica, Bethany L Niell, Jennifer Drukteinis, Mary S Newell, Michael A Cohen, Marina Giurescu, Elise Berman, Constance Lehman, Savannah C Partridge, Kimberly A Fitzpatrick, Marisa H Borders, Wei T Yang, Basak Dogan, Sally Goudreau, Thomas Chenevert, Christina Yau, Angela Demichele, Don Berry, Laura J Esserman, Nola M Hylton

Articles, Abstracts, and Reports

Dynamic contrast-enhanced (DCE) MRI provides both morphological and functional information regarding breast tumor response to neoadjuvant chemotherapy (NAC). The purpose of this retrospective study is to test if prediction models combining multiple MRI features outperform models with single features. Four features were quantitatively calculated in each MRI exam: functional tumor volume, longest diameter, sphericity, and contralateral background parenchymal enhancement. Logistic regression analysis was used to study the relationship between MRI variables and pathologic complete response (pCR). Predictive performance was estimated using the area under the receiver operating characteristic curve (AUC). The full cohort was stratified by hormone receptor (HR) and …

The Unorthodox - Volume 3, Issue 3, Morehead State University. Honors Program.

Newsletters & Publications

Volume 3, Issue 3 of The Unorthodox. Published on November 27, 2020.

Lyme Disease In Kentucky: Prevalence, Awareness, And Diagnosis In A Conventionally Low-Endemic Area, Rachel L. Carden Ots

Honors Theses

Lyme Disease is the fastest-growing vector-borne illness in the United States – including in low-endemic states, such as Kentucky; given Kentucky’s low Lyme disease incidence in prior decades, it has since experienced an increase of cases despite a lack of discussion on the condition and its implications on patient health and wellbeing. To measure current levels of knowledge and awareness of Lyme disease in Kentucky residents, a survey was distributed to Microbiology and Honors Program students at Eastern Kentucky University, and its results were discussed. While Lyme disease cases do continue to rise, the general public of Kentucky lacks in …

December 3, 2020: Agenda, University Of North Dakota

University Senate Meeting Minutes

Agenda for the December 3, 2020, meeting of the University Senate. 49 pages

Chloramination Of Iopamidol- And Bromide-Spiked Waters Containing Natural Organic Matter, Nana Osei B Ackerson, Hannah K. Liberatore, Susan D. Richardson, Micheal J. Plewa, Thomas A. Ternes, Stephen E. Duirk

Faculty Publications

Iopamidol (an iodinated X-ray contrast medium) and bromide are precursors in the formation of halogenated disinfection byproducts (DBPs). The interactions of these precursors are vital to elucidate the formation of halogenated DBPs during chloramination. This work investigated the formation of total organic halogen and select individual DBPs in two laboratory-chloraminated source waters containing iopamidol and bromide. Experiments were carried out in batch reactors containing Barberton source water (BSW) and Cleveland BSW (CSW), spiked with iopamidol (5 mu M), bromide (15 mu M), and 100 mu M monochloramine. Total organic iodine concentrations were approximately equal regardless of source water since they …

Cancer-Associated Fibroblast Density, Prognostic Characteristics, And Recurrence In Head And Neck Squamous Cell Carcinoma: A Meta-Analysis., Alexander M Knops, Andrew South, Ulrich Rodeck, Ubaldo Martinez-Outschoorn, Larry A Harshyne, Jennifer Johnson, Adam J Luginbuhl, Joseph M Curry

Department of Otolaryngology - Head and Neck Surgery Faculty Papers

Introduction: The progression and clinical course of head and neck squamous cell carcinoma (HNSCC) relies on complex interactions between cancer and stromal cells in the tumor microenvironment (TME). Among the most abundant of these stromal cells are cancer-associated fibroblasts (CAFs). While their contribution to tumor progression is widely acknowledged, and various CAF-targeted treatments are under development, the relationship between CAF density and the clinicopathologic course of HNSCC has not been clearly defined. Here we examine the published evidence investigating the relationship of cancer-associated fibroblasts to local recurrence and indicators of prognostic significance in HNSCC.

Methods: We conducted a meta-analysis of …

Cancer-Associated Fibroblast Density, Prognostic Characteristics, And Recurrence In Head And Neck Squamous Cell Carcinoma: A Meta-Analysis., Alexander M Knops, Andrew South, Ulrich Rodeck, Ubaldo Martinez-Outschoorn, Larry Harshyne, Phd, Jennifer Johnson, Md, Adam J Luginbuhl, Joseph M Curry

Department of Otolaryngology - Head and Neck Surgery Faculty Papers

Introduction: The progression and clinical course of head and neck squamous cell carcinoma (HNSCC) relies on complex interactions between cancer and stromal cells in the tumor microenvironment (TME). Among the most abundant of these stromal cells are cancer-associated fibroblasts (CAFs). While their contribution to tumor progression is widely acknowledged, and various CAF-targeted treatments are under development, the relationship between CAF density and the clinicopathologic course of HNSCC has not been clearly defined. Here we examine the published evidence investigating the relationship of cancer-associated fibroblasts to local recurrence and indicators of prognostic significance in HNSCC.

Methods: We conducted a meta-analysis of …

Tackle Epithelial-Mesenchymal Transition With Epigenetic Drugs In Cancer, Bo Dong, Zhaoping Qiu, Yadi Wu

Pharmacology and Nutritional Sciences Faculty Publications

Epithelial-mesenchymal Transition (EMT) is a de-differentiation process in which epithelial cells lose their epithelial properties to acquire mesenchymal features. EMT is essential for embryogenesis and wound healing but is aberrantly activated in pathological conditions like fibrosis and cancer. Tumor-associated EMT contributes to cancer cell initiation, invasion, metastasis, drug resistance and recurrence. This dynamic and reversible event is governed by EMT-transcription factors (EMT-TFs) with epigenetic complexes. In this review, we discuss recent advances regarding the mechanisms that modulate EMT in the context of epigenetic regulation, with emphasis on epigenetic drugs, such as DNA demethylating reagents, inhibitors of histone modifiers and non-coding …

Desirability Of Outcome Ranking For The Management Of Antimicrobial Therapy (Door Mat): A Framework For Assessing Antibiotic Selection Strategies In The Presence Of Drug Resistance, Brigid M. Wilson, Robin L.P. Jump, Federico Perez, Robert A. Bonomo

Faculty Scholarship

The complexities of antibiotic resistance mean that successful stewardship must consider both the effectiveness of a given antibiotic and the spectrum of that therapy to minimize imposing further selective pressure. To meet this challenge, we propose the Desirability of Outcome Ranking approach for the Management of Antimicrobial Therapy (DOOR MAT), a flexible quantitative framework that evaluates the desirability of antibiotic selection. Herein, we describe the steps required to implement DOOR MAT and present examples to illustrate how the desirability of treatment selection can be evaluated using resistance information. While treatments and the scoring of treatment selections must be adapted to …

Eosinophil Micrornas Play A Regulatory Role In Allergic Diseases Included In The Atopic March., Émile Bélanger, Anne-Marie Madore, Anne-Marie Boucher-Lafleur, Marie-Michelle Simon, Tony Kwan, Tomi Pastinen, Catherine Laprise

Manuscripts, Articles, Book Chapters and Other Papers

(1) Background: The atopic march is defined by the increased prevalence of allergic diseases after atopic dermatitis onset. In fact, atopic dermatitis is believed to play an important role in allergen sensitization via the damaged skin barrier, leading to allergic diseases such as allergic asthma and allergic rhinitis. The eosinophil, a pro-inflammatory cell that contributes to epithelial damage, is one of the various cells recruited in the inflammatory reactions characterizing these diseases. Few studies were conducted on the transcriptome of this cell type and even less on their specific microRNA (miRNA) profile, which could modulate pathogenesis of allergic diseases and …

Interview With Emily Duffy, Emily Duffy

Auntie Sewing Squad Interviews

Emily Duffy is a practicing Pagan woman of Jewish descent, currently living in northern California. Her work in the fashion industry has taken her to LA and San Francisco, but is content living out her later years outside the big cities. FIDM taught her how to sew with industrial techniques, which has heavily influenced her mask-making processes. Aside from her work as a professional fine artist--creating sociopolitically significant work--Duffy finds fulfillment in activist work too. From starting an abortion rights club at Cal, contributing to the Howard Dean campaign, and now sewing masks and organizing "asks" with the Auntie Sewing …

Biosynthetic Gene Clusters, Microbiomes, And Secondary Metabolites In Cold Water Marine Organisms, Nicole Elizabeth Avalon

USF Tampa Graduate Theses and Dissertations

Microorganisms and invertebrate animals from cold water marine environments, such as in Antarctica and in Ireland’s deep sea, are a rich source of secondary metabolites. In this dissertation, research was centered around secondary metabolism and natural product biosynthesis. The projects include the delineation of biosynthetic gene clusters hypothesized to be responsible for the biosynthesis of the palmerolides, stratification of the microbiome of the Antarctic ascidian Synoicum adareanum, genomic and peptidomic analysis of a host-associated Antarctic Pseudovibrio sp., and isolation and characterization of secondary metabolites from the Irish deep-sea coral Drifa sp.

Palmerolide A, the principle secondary metabolite associated with S. …

Characterization Of Pathogen Airborne Inoculum Density By Information Theoretic Analysis Of Spore Trap Time Series Data, Robin A. Choudhury, Neil Mcroberts

School of Earth, Environmental, & Marine Sciences Faculty Publications

In a previous study, air sampling using vortex air samplers combined with species-specific amplification of pathogen DNA was carried out over two years in four or five locations in the Salinas Valley of California. The resulting time series data for the abundance of pathogen DNA trapped per day displayed complex dynamics with features of both deterministic (chaotic) and stochastic uncertainty. Methods of nonlinear time series analysis developed for the reconstruction of low dimensional attractors provided new insights into the complexity of pathogen abundance data. In particular, the analyses suggested that the length of time series data that it is practical …

Nocturnal Surface Urban Heat Island Over Greater Cairo: Spatial Morphology, Temporal Trends And Links To Land-Atmosphere Influences, Am El Kenawy, M Hereher, Sm Robaa, Mf Mccabe, Et Al

School of Geography, Earth and Environmental Sciences

This study assesses the spatial and temporal characteristics of nighttime surface urban heat island (SUHI) effects over Greater Cairo: the largest metropolitan area in Africa. This study employed nighttime land surface temperature (LST) data at 1 km resolution from the Moderate Resolution Imaging Spectroradiometer (MODIS) Aqua sensor for the period 2003–2019. We presented a new spatial anomaly algorithm, which allowed to define SUHI using the most anomalous hotspot and cold spot of LST for each time step over Greater Cairo between 2003 and 2019. Results demonstrate that although there is a significant increase in the spatial extent of SUHI over …