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Electrowetting-On-Dielectric (Ewod): Current Perspectives And Applications In Ensuring Food Safety, Snigdha Roy Barman, Imran Khan, Subhodeep Chatterjee, Subhajit Saha, Dukhyun Choi, Sangmin Lee, Zong-Hong Lin

Journal of Food and Drug Analysis

Digital microfluidic (DMF) platforms have contributed immensely to the development of multifunctional lab-on-chip systems for performing complete sets of biological and analytical assays. Electrowetting-on-dielectric (EWOD) technology, due to its outstanding flexibility and integrability, has emerged as a promising candidate for such lab-on-chip applications. Triggered by an electrical stimulus, EWOD devices allow precise manipulation of single droplets along the designed electrode arrays without employing external pumps and valves, thereby enhancing the miniaturization and portability of the system towards transcending important laboratory assays in resource-limited settings. In recent years, the simple fabrication process and reprogrammable architecture of EWOD chips have led to …

Detection Of Crispr-Mediated Genome Modifications Through Altered Methylation Patterns Of Cpg Islands., M Heath Farris, Pamela A Texter, Agustin A Mora, Michael V. Wiles, Ellen F Mac Garrigle, Sybil A Klaus, Kristine Rosfjord

Faculty Research 2020

BACKGROUND: The development and application of CRISPR technologies for the modification of the genome are rapidly expanding. Advances in the field describe new CRISPR components that are strategically engineered to improve the precision and reliability of CRISPR editing within the genome sequence. Genome modification using induced genome breaks that are targeted and mediated by CRISPR components leverage cellular mechanisms for repair like homology directed repair (HDR) to incorporate genomic edits with increased precision.

RESULTS: In this report, we describe the gain of methylation at typically hypomethylated CpG island (CGI) locations affected by the CRISPR-mediated incorporation of donor DNA using HDR …

Aligning Food Environments With Institutional Values: A Mixed Methods Study Of Oregon Health Care Organizations, Elizaveta Walker

Dissertations and Theses

A major driver of the obesity epidemic is obesogenic food environments, characterized by nutrient-poor and energy-dense foods that saturate the collective physical, economic and sociocultural conditions that influence nutritional status. Food environments in organizations such as hospitals and public health agencies warrant special consideration given their health-focused mission. Improving food environments within health care settings has been highlighted by the Centers for Disease Control and Prevention (CDC) as one of seven key strategies to prevent obesity. However, most of the refereed literature examining healthy food environment policies (HFEPs) within hospitals focuses on the inpatient dietary environment, leaving a paucity of …

We Are...Marshall, December 2, 2020, Office Of Marshall University Communications

We Are ... Marshall: the Newsletter for Marshall University 1999-2023

No abstract provided.

Fall Newsletter 2020 (Issue 10), Csusb

Coyote Chronicle (1984-)

Inside This Issue

• Restaurants and bars in Coachella Valley adjust to COVID-19 protocols
• Small businesses struggle to survive in pandemic-oriented film industry
• Inland Empire residents voice concerns over smog growth
• Opinion: Reflecting on 2020 as a year of change
• Student shares experience with electronic music production project
• Vox pop: How are CSUSB athletes staying in shape during the pandemic?
• Opinion: Looking back on CSUSB's transition to semesters
• Local streamer and business owner talks Twitch
• How the Multicultural Greek Council functions during the pandemic
• Advice: How to combat virtual spring semester

The Role Of Citizen Science In Science Perception, Meaning, And Environmental Values: An Evaluation Of The Living Snow Project, Rachel L. Severson, Phoebe S. Bean, Cali Caughie, Robin Kodner

Psychology Faculty Publications

Citizen science programs provide a means for outdoor enthusiasts to combine their recreational pursuits with engagement in science. This research evaluated the role of citizen science in peoples’ perceptions of science, meaningfulness of their outdoor experiences, and environmental attitudes, identity, and connection. The Living Snow Project (LSP), a community-enabled (citizen science) program, engages the outdoor recreation community in research characterizing alpine snow microbiomes through volunteer sample collections in alpine environments. Citizen scientists (N=41) volunteering with LSP participated in this study at two time points before and after the 2019 snow sampling season. At both time points, participants completed five well-established …

Ask The Experts About Coronavirus Vaccine, Herd Immunity, Work From Home, Dec. 15, Ohio University College Of Arts & Sciences

All Forum Articles

No abstract provided.

Bell And Moran Publish On Italian Pow Foodways In Britain In World War Ii, Present On Italian Culinary Identity In World War I, Ohio University College Of Arts & Sciences

All Forum Articles

No abstract provided.

Counseling Adolescents With Chronic Physical Chronic Conditions, Holly Dwyer

Counselor Education Capstones

The following paper will address the counseling considerations of children and adolescents who have physical chronic conditions. Mental health counselors must be aware of specific needs for this population including co-occurring mental health disorders, impacts of primary identifiers, and suggestions for implementing a biopsychosocial approach to counseling, which includes both cognitive behavioral and existential interventions.

Smart Homes For Smart Health: Developing An Interactive System To Reduce In-Home Secondhand Smoke, Christie Kika, Janice Han, Vincent Berardi

Student Scholar Symposium Abstracts and Posters

Smoke from any source is potentially harmful because it contains fine particulate matter that is associated with acute and chronic conditions. Second-hand smoke (SHS) is particularly unsafe for children due to biological characteristics (higher breathing rates, immature lungs and underdeveloped immune systems) that make it difficult to filter toxins.To address this concern, we recently completed Project Fresh Air (PFA), an NIH-funded R01 intervention that installed air particle sensors in the households of tobacco smokers who lived with children. The purpose of our research is to investigate and develop efficient smart home devices that monitor SHS in various living spaces to …

New Activity Found For Chd7, A Protein Factor Vital In Embryonic Development, Jeff Hansen

Browse All News

No abstract provided.

December 2, 2020 Faculty Senate Minutes, University Of South Carolina

Faculty Senate

No abstract provided.

Birds Ruffled By Big-City Lights, Lauren E. Nadler

Marine & Environmental Sciences Faculty Articles

No abstract provided.

Groundwater Production From Geothermal Heating On Early Mars And Implication For Early Martian Habitability, Lujendra Ojha, Jacob Buffo, Suniti Karunatillake, Matthew Siegler

Faculty Publications

Copyright © 2020 The Authors, In explaining extensive evidence for past liquid water, the debate on whether Mars was primarily warm and wet or cold and arid 4 billion years (Ga) ago has continued for decades. The Sun’s luminosity was ~30% lower 4 Ga ago; thus, most martian climate models struggle to elevate the mean surface temperature past the melting point of water. Basal melting of ice sheets may help resolve that paradox. We modeled the thermophysical evolution of ice and estimate the geothermal heat flux required to produce meltwater on a cold, arid Mars. We then analyzed geophysical and …

Yap/Taz Deficiency Reprograms Macrophage Phenotype And Improves Infarct Healing And Cardiac Function After Myocardial Infarction, Masum M. Mia, Dasan Mary Cibi, Siti Aishah Binte Abdul Ghani, Weihua Song, Nicole Tee, Sujoy Ghosh, Junhao Mao, Eric N. Olson, Manvendra K. Singh

Division of Basic Science Faculty Publications

Adverse cardiac remodeling after myocardial infarction (MI) causes structural and functional changes in the heart leading to heart failure. The initial post-MI pro-inflammatory response followed by reparative or anti-inflammatory response is essential for minimizing the myocardial damage, healing, and scar formation. Bone marrow-derived macrophages (BMDMs) are recruited to the injured myocardium and are essential for cardiac repair as they can adopt both pro-inflammatory or reparative phenotypes to modulate inflammatory and reparative responses, respectively. Yes-associated protein (YAP) and transcriptional coactivator with PDZ-binding motif (TAZ) are the key mediators of the Hippo signaling pathway and are essential for cardiac regeneration and repair. …

Universal Molecular Processor For Precision Medicine, Steven A. Soper, Francis Barany, Sunggook Park, Michael Murphy, Collin J. Mckinney, John William Efcavitch, Mateusz L. Hupert

College of Science Patents

No abstract provided.

Lc-Ms/Ms Quantification Of Nevirapine And Its Metabolites In Hair For Assessing Long-Term Adherence, Haoran Yang, Liuxi Chu, Yan Wu, Wei Wang, Jin Yang, Quan Zhang, Shan Qiao Ph.D., Xiaoming Li Ph. D., Zhiyong Shen, Yuejiao Zhou, Shuaifeng Liu, Huihua Deng

Faculty Publications

The adherence assessment based on the combination of nevirapine (NVP) and its two metabolites (2-hydroxynevirapine and 3-hydroxynevirapine) would more comprehensively and accurately reflect long-term adherence than that of a single prototype. This study aimed to develop a specific, sensitive and selective method for simultaneous detection of the three compounds in hair and explore whether there was consistency among the three compounds in assessing long-term adherence. Furthermore, 75 HIV-positive patients who were taking the NVP drug were randomly recruited and divided into two groups (high-and low-adherence group). All participants self-reported their days of oral drug administration per month and provided their …

December 2, 2020, Faculty, Illinois Wesleyan University

2020-2021

No abstract provided.

Tunel Apoptotic Cell Detection In Stony Coral Tissue Loss Disease (Sctld): Evaluation Of Potential And Improvements, E. Murphy Mcdonald

All HCAS Student Capstones, Theses, and Dissertations

Stony coral tissue loss disease (SCTLD) is a highly lethal coral disease that has caused a dramatic loss of coral tissue along the Florida Reef Tract and throughout the Wider Caribbean. This study seeks to understand whether programmed cell death (apoptosis) is involved in the pathology of the highly virulent SCTLD tissue loss lesion. Tissues from diseased colonies of Pseudodiploria strigosa collected in 2018 and 2020 were stained using the terminal deoxyribonucleotidyltransferase (TdT) mediated dUTP-biotin nick end labeling (TUNEL) assay to visualize areas of programmed cell death. The archived tissue samples collected in 2018 exhibited a significantly higher degree of …

Supports Used By Black Women Faculty For Career Advancement At Historically Black Colleges And Universities, Andrea Delpriore

Seton Hall University Dissertations and Theses (ETDs)

This study investigated the supports utilized by Black women in their career advancement as faculty members at Historically Black Colleges and Universities. Although there is an abundance of scholarship about the challenges presented to Black women faculty at Predominantly White Institutions, the career advancement of Black women faculty at Historically Black Colleges and Universities has gone largely unstudied. Considering Historically Black Colleges and Universities are where Black women faculty achieve tenure in the highest percentages, this study took a non-deficit perspective and investigated what supports are used by Black women faculty internal to the institution, external to the institution, as …

An Update Of The Virion Proteome Of Kaposi Sarcoma-Associated Herpesvirus, Ramina Nabiee, Basir Syed, Jesus Ramirez Castano, Rukhsana Lalani, Jennifer Totonchy

Pharmacy Faculty Articles and Research

The virion proteins of Kaposi sarcoma-associated herpesvirus (KSHV) were initially characterized in 2005 in two separate studies that combined the detection of 24 viral proteins and a few cellular components via LC-MS/MS or MALDI-TOF. Despite considerable advances in the sensitivity and specificity of mass spectrometry instrumentation in recent years, leading to significantly higher yields in detections, the KSHV virion proteome has not been revisited. In this study, we have re-examined the protein composition of purified KSHV virions via ultra-high resolution Qq time-of-flight mass spectrometry (UHR-QqTOF). Our results confirm the detection of all previously reported virion proteins, in addition to 17 …

Fall 2020 Student Scholar Symposium Abstract Volume, Chapman University Center For Undergraduate Excellence

Student Scholar Symposium Abstracts and Posters

No abstract provided.

Discordant Responses Between Primary Head And Neck Tumors And Nodal Metastases Treated With Neoadjuvant Nivolumab: Correlation Of Radiographic And Pathologic Treatment Effect., Dante J. Merlino, Jennifer M. Johnson, Madalina Tuluc, Stacey Gargano, Robert Stapp, Larry Harshyne, Benjamin E. Leiby, Adam Flanders, Ralph Zinner, Rita Axelrod, Joseph Curry, David M. Cognetti, Kyle Mannion, Young J. Kim, Ulrich Rodeck, Athanassios Argiris, Adam J. Luginbuhl

Department of Medical Oncology Faculty Papers

PD-1 blockade represents a promising treatment in patients with head and neck squamous cell carcinoma (HNSCC). We analyzed results of a neoadjuvant randomized window-of-opportunity trial of nivolumab plus/minus tadalafil to investigate whether immunotherapy-mediated treatment effects vary by site of involvement (primary tumor, lymph nodes) and determine how radiographic tumor shrinkage correlates with pathologic treatment effect.

Patients and Methods: Forty-four patients enrolled in trial NCT03238365 were treated with nivolumab 240 mg intravenously on days 1 and 15 with or without oral tadalafil, as determined by random assignment, followed by surgery on day 31. Radiographic volumetric response (RVR) was defined as percent …

Exercise As An Adjuvant To Cartilage Regeneration Therapy, John Kelly Smith

ETSU Faculty Works

This article provides a brief review of the pathophysiology of osteoarthritis and the ontogeny of chondrocytes and details how physical exercise improves the health of osteoarthritic joints and enhances the potential of autologous chondrocyte implants, matrix-induced autologous chondrocyte implants, and mesenchymal stem cell implants for the successful treatment of damaged articular cartilage and subchondral bone. In response to exercise, articular chondrocytes increase their production of glycosaminoglycans, bone morphogenic proteins, and anti-inflammatory cytokines and decrease their production of proinflammatory cytokines and matrix-degrading metalloproteinases. These changes are associated with improvements in cartilage organization and reductions in cartilage degeneration. Studies in humans indicate …

Literature Review: Global Neonicotinoid Insecticide Occurrence In Aquatic Environments, Josephus F. Borsuah, Tiffany L. Messer, Daniel D. Snow, Steve D. Comfort, Aaron R. Mittelstet

Biosystems and Agricultural Engineering Faculty Publications

Neonicotinoids have been the most commonly used insecticides since the early 1990s. Despite their efficacy in improving crop protection and management, these agrochemicals have gained recent attention for their negative impacts on non-target species such as honeybees and aquatic invertebrates. In recent years, neonicotinoids have been detected in rivers and streams across the world. Determining and predicting the exposure potential of neonicotinoids in surface water requires a thorough understanding of their fate and transport mechanisms. Therefore, our objective was to provide a comprehensive review of neonicotinoids with a focus on their fate and transport mechanisms to and within surface waters …

Fluorescence Spectroscopic And Molecular Modelling Studies On The Molecular Interaction Mechanism Of Bromodeoxyuridine With Human Serum Albumin, Amira Adlin Roslan

Student Works (2020-2029)

The interaction of a nucleoside analogue, bromodeoxyuridine (BrdU) with human serum albumin (HSA) was studied to investigate the binding phenomenon and analyze the protein conformation upon BrdU binding. Multiple spectroscopic techniques, viz. intrinsic and three-dimensional (3-D) fluorescence, ultraviolet-visible (UV-Vis) absorption and circular dichroism (CD) spectroscopy along with molecular docking were used. A decrease in the Stern-Volmer constant (Ksv) with the increase in temperature suggested BrdU-induced quenching of protein fluorescence as static quenching and thus implied BrdU−HSA complex formation. This was also supported by UV-Vis absorption spectral results, showing hyperchromism in the absorption spectrum of HSA upon BrdU addition. Intermediate binding …

Bibliometric Analysis Of The Literature In The Field Of Information Technology Relatedness, Ilham M, Anis Eliyana, Praptini Yulianti

Library Philosophy and Practice (e-journal)

This bibliometric describe Information Technology Relateness is defined as the use of information technology infrastructure and information technology management processes betweeWas this submission previously published in a journal? Bepress will automatically create an OpenURL for published articles. Learn more about OpenURLsn business units together. There is not much research on Information Technology Relateness by providing a big picture that is visualized from year to year. This study aims to map research in the field of Information Technology Relateness with data from all international research publications. This study performs a bibliometric method and analyzes research data using the Services Analyze …

Improve The Prototype Of Low-Cost Near-Infrared Diffuse Optical Imaging System, Chen Xu, Mohammed Z. Shakil

Publications and Research

Diffuse Optical Tomography (DOT) and Optical Spectroscopy using near-infrared (NIR) diffused light has demonstrated great potential for the initial diagnosis of tumors and in the assessment of tumor vasculature response to neoadjuvant chemotherapy. The aims of this project are 1) to test the different types of LEDs in the near-infrared range, and design the driving circuit, and test the modulation of LEDs at different frequencies; 2) to test the APDs as a detector, and build the receiver system and compare efficiency with pre-built systems. In this project, we are focusing on creating a low-cost infrared transmission system for tumor and …

Pediatric Asthma And Psychological Resilience: Examining Whether Family Functioning And Social Support Relate To Asthma Symptoms And Lung Function, Dalia Jaafar, Natasha H. Hikita, Pornchai Tirakitsoontorn, Azucena Talamantes, Anchalee Yuengsrigul, Eric Sternlicht, Brooke N. Jenkins

Student Scholar Symposium Abstracts and Posters

Upwards of 6 million children in the United States are afflicted with pediatric asthma. While previous research has linked asthma to multiple contributing biological and environmental factors, recent research suggests that psychological and social factors may have an impact on physiological outcomes of asthma like lung function and lung inflammation. Therefore, we suggest the need to study the impact of positive psychological factors such as a well-functioning family environment and beneficial social support on symptoms and lung function of children diagnosed with asthma. In the present pilot study, we recruited a total of 15 children with a confirmed asthma diagnosis …

Floral Variation Across Three Varieties Of The Landscape-Dominant Tree Metrosideros Polymorpha (Myrtaceae): Insights From A Hawaii Island Common Garden, Elizabeth A. Stacy, Melissa A. Johnson

Life Sciences Faculty Research

Premise of research: Metrosideros polymorpha is a landscape-dominant tree species endemic to the Hawaiian Islands. Although the group is famous for its ecological amplitude and variation in vegetative characters, little attention has been paid to variation in its “shaving brush” flowers, which occur in inflorescences of diverse sizes and colors. We aimed to determine whether the floral variation observed in natural populations is heritable and how this variation is distributed across environments and varieties of the species. Methodology: We measured seven floral traits in 93 adult trees representing three varieties of M. polymorpha in a common garden on the island …