Digital Commons Network^™

Context Effects On Child Object Touch And Parent Referential Speech: Implications For Autism Spectrum Disorder, Amanda Mankovich

Master's Theses

Object play provides a critical setting for early learning (West & Iverson, 2017). Previous research has established a role for context (i.e., type of activity and parent input), in shaping child touch behaviors. Although several studies have investigated the development object play, many miss key characteristics of everyday environments. Using data from the Longitudinal Study of Early Language (Naigles & Fein, 2017), we investigated how play is affected by development, parent input, and engagement in various activities across both typically developing (TD) children and children with autism spectrum disorder (ASD). We analyzed object prompts and independently coded moments toddlers touched …

Potential Effects Of Climate Change On The Geographic Distribution Of The Endangered Plant Species Manihot Walkerae, Gisel Garza, Armida Rivera, Crystian Sadel Venegas Barrera, Jose Guadalupe Martinez-Avalos, Jon Dale, Teresa Patricia Feria-Arroyo

School of Integrative Biological & Chemical Sciences (Formerly Dept. of Biology)

Walker’s Manihot, Manihot walkerae, is an endangered plant that is endemic to the Tamaulipan thornscrub ecoregion of extreme southern Texas and northeastern Mexico. M. walkerae populations are highly fragmented and are found on both protected public lands and private property. Habitat loss and competition by invasive species are the most detrimental threats for M. walkerae; however, the effect of climate change on M. walkerae’s geographic distribution remains unexplored and could result in further range restrictions. Our objectives are to evaluate the potential effects of climate change on the distribution of M. walkerae and assess the usefulness of natural protected areas …

Testing Diversity Effects Of Forage Biodiversity In The Karst Region Of Southwestern China, Min Wang, Zhiliang Tan, Aijun Yi, Kelin Wang, Jue Zhu

IGC Proceedings (1977-2023)

No abstract provided.

Studies Of Population Characteristic Affecting Senescence Of Elymus Sibiricus, J. W. Wang, Y. S. You, Kun Wang

IGC Proceedings (1977-2023)

No abstract provided.

We Are...Marshall, June 17, 2020, Office Of Marshall University Communications

We Are ... Marshall: the Newsletter for Marshall University 1999-2023

No abstract provided.

Circuits With Broken Fibration Symmetries Perform Core Logic Computations In Biological Networks, Ian Leifer, Flaviano Morone, Saulo D. S. Reis, José S. Andrade Jr., Mariano Sigman, Hernán A. Makse

Publications and Research

We show that logic computational circuits in gene regulatory networks arise from a fibration symmetry breaking in the network structure. From this idea we implement a constructive procedure that reveals a hierarchy of genetic circuits, ubiquitous across species, that are surprising analogues to the emblematic circuits of solid-state electronics: starting from the transistor and progressing to ring oscillators, current-mirror circuits to toggle switches and flip-flops. These canonical variants serve fundamental operations of synchronization and clocks (in their symmetric states) and memory storage (in their broken symmetry states). These conclusions introduce a theoretically principled strategy to search for computational building blocks …

Good Initiative, Bad Judgement: The Unintended Consequences Of Title Ix's Proportionality Standard On Ncaa Men's Gymnastics And The Transgender Athlete, Jeffrey Shearer

Pace Intellectual Property, Sports & Entertainment Law Forum

Title IX fails to provide the tools or guidelines necessary to equalize opportunities for all student athletes in the collegiate setting despite the government’s continuous effort to explain the law. This failure is because judicial precedent has largely developed around the binary proportionality test of compliance. Title IX was originally intended to equalize educational opportunities for male and female students in order to remedy past discrimination in our society. However, the application of Title IX has frequently created fewer opportunities in athletics due to the unintended relationship between the proportionality standard and the social phenomenon that is the commercialization of …

Toxin Transcripts In Crotalus Atrox Venom And In Silico Structures Of Toxins, Ying Jia, Ivan Lopez, Paulina Kowalski

School of Integrative Biological & Chemical Sciences (Formerly Dept. of Biology)

The western diamondback rattlesnake (Crotalus atrox) is a common and widespread North American pit viper species, and its venom possesses medical applications. In this research, we identified 14 of the most common transcripts encoding 11 major venom toxins including transcripts for a three-finger toxin (3FTx) from the crude venom of C. atrox. In silico three-dimensional (3D) structures of 9 venom toxins were predicted by using deduced toxin amino acid sequences and a computer programme-MODELLER. The accuracy of all predicted toxin structures was evaluated by five stereochemical structure parameters including discrete optimised protein energy (DOPE) score, root mean square deviation (RMSD), …

Creating Library Learning Spaces That Support Twenty-First Century Pedagogy And Student Learning, Deborah Lynn Christoffersen

Theses and Dissertations

University libraries struggle to keep up with rapidly changing technology and the associated change in teaching strategy. Most administrators and librarians are often not trained to assess space needs and struggle to reassign library spaces for non-traditional library use. As such, they often embark on expensive and time-consuming feasibility studies, using (typically) hard-earned monies to complete the research or to pilot a new space. What academic research library administrators and staff lack is an analysis tool for discovering and planning needed renovations and improvements in aging library facilities. The purpose of this research project was to determine how students use …

Marked Variability In Bioactivity Between Commercially Available Bovine Colostrum For Human Use; Implications For Clinical Trials, Rj Playford, M Cattell, T Marchbank

Peninsula Medical School

BACKGROUND: Colostrum, the milk produced during first few days after birth, is rich in immunoglobulins, antimicrobial peptides & growth factors. Multiple clinical trials using bovine colostrum are ongoing but with no assessment of test product bioactivity. OBJECTIVES: To examine variability of bioactivity between 20 commercial colostrum products, contribution of TGFß and EGFR in mediating effects, heat sensitivity of bioactivity and changes in bioactivity of colostrum milkings in the days following calving. DESIGN: In vitro bioactivity used AGS, RIE-1 and Caco-2 cell proliferation (Alamar blue) and migration (wounded monolayers) assays. Changes in colostrum bioactivity determined following addition of TGFß-neutralising antibody, EGFR …

Ambrein: A Minor, But Common Constituent Of Mammalian Faeces?, Steven J. Rowland, Paul A. Sutton, Der Lühe B Von, John K. Volkman, Christopher H. Vane, Simon N. Ingram, Charlotte Dunn, Diane Claridge

More Faculty of Science and Engineering Research

No abstract provided.

Declines Of Black-Billed Magpie (Pica Hudsonia) And Black-Capped Chickadee (Poecile Atricapillus) In The North-Central United States Following The Invasion Of West Nile Virus, Stephen J. Brenner, Joel G. Jorgensen

Western North American Naturalist

West Nile virus (WNV) is an introduced pathogen, transmitted by mosquitos, that spread across North America following its arrival there in 1999. Birds host the virus, but consequences of the disease to bird species have been variable. A small number of avian species are especially susceptible to WNV, experience high mortality rates when infected, and have shown regional declines apparently because of the disease. Other species have seemingly been unaffected. Transmission of WNV is associated with climate, with higher incidence of transmission in dry areas with warm winters. The north-central United States is an area that exhibits clines in temperature …

25-Hydroxycholesterol Amplifies Microglial Il-1Β Production In An Apoe Isoform-Dependent Manner, Man Ying Wong, Michael Lewis, James J Doherty, Yang Shi, Anil G Cashikar, Anna Amelianchik, Svitlana Tymchuk, Patrick M Sullivan, Mingxing Qian, Douglas F Covey, Gregory A Petsko, David M Holtzman, Steven M Paul, Wenjie Luo

2020-Current year OA Pubs

BACKGROUND: Genome-wide association studies of Alzheimer's disease (AD) have implicated pathways related to lipid homeostasis and innate immunity in AD pathophysiology. However, the exact cellular and chemical mediators of neuroinflammation in AD remain poorly understood. The oxysterol 25-hydroxycholesterol (25-HC) is an important immunomodulator produced by peripheral macrophages with wide-ranging effects on cell signaling and innate immunity. Cholesterol 25-hydroxylase (CH25H), the enzyme responsible for 25-HC production, has also been found to be one of the disease-associated microglial (DAM) genes that are upregulated in the brain of AD and AD transgenic mouse models.

METHODS: We used real-time PCR and immunoblotting to examine …

Pedagogical Approaches And Instructional Content That Predict Increased Acceptance Of Biological Evolution In University Students, Clinton Thomas Laidlaw

Theses and Dissertations

Evolution is the central organizing theory of biology. Without evolutionary theory, biology becomes a somewhat tangential assemblage of facts about living organisms, which is precisely how it is viewed by many students. Many teachers teach evolution in a limited capacity or avoid it entirely due to fear of opposition, lack of confidence in their own understanding, or lack of acceptance of the theory themselves. When evolution is not taught, or is not accepted, it cannot be utilized to make sense of the field, and is quickly forgotten by students. While some studies have shown a correlation between instruction about evolution …

Entropy's Child, Brandon Reed Boulton

Theses and Dissertations

Art, process, and materials offer me an escape from the sometimes-crushing realities of my personal struggle with chronic mental illness. Escape is often my primary motivator for making art. However, personal meaning and understanding sometimes come while I'm working in the studio. Sometimes the meanings of the work only become clear years later. Personal experience and experimenting with materials and processes have led me to an appreciation and awareness of entropy--the second law of thermodynamics. My sculptures use spontaneity, abstraction, and process to dialogue with entropy.

A Corpus-Based Study Of The Gender Assignment Of Nominal Anglicisms In Brazilian Portuguese, Taryn Marie Skahill

Theses and Dissertations

The purpose of this study is to analyze the variability of gender assignment to nominal anglicisms in Brazilian Portuguese and to identify how the orthography of English loanwords and their establishment in the language influences such variation. This study also seeks to identify the most important factors that govern such gender assignment. The data were gathered from two Portuguese corpora, one consisting of more formal and edited language (Corpus do Português, News on the Web) and the other consisting of less formal and unaltered language, such as blog posts (Corpus do Português, Web/Dialects). Forty anglicisms were analyzed in order to …

A Lysine-Modified Polyethersulfone (Pes) Membrane For The Recovery Of Lanthanides, Ming Yu, Julie N. Renner, Christine E. Duval

Faculty Scholarship

Rare-earth elements (which include all lanthanides, scandium, and yttrium) play a key role in many fields including oil refining, metallurgy, electronics manufacturing, and other high-technology applications. Although the available lanthanide resources are enough for current levels of manufacturing, increased future demand for lanthanides will require new, efficient recovery methods to provide a sustainable supply. Membrane adsorbers are promising separation materials to recover lanthanides from high volumes of wastewater due to their tailorable surface chemistry, high binding capacity and high throughput. In this work, membrane adsorbers were synthesized by first using ultraviolet-initiated free radical polymerization to graft a poly(glycidyl methacrylate) (p-GMA) …

A Novel Hotspot And Rare Somatic Mutation P.A138v, At Tp53 Is Associated With Poor Survival Of Pancreatic Ductal And Periampullary Adenocarcinoma Patients, Gourab Saha, Richa Singh, Argha Mandal, Subrata Das, Esita Chattopadhyay, Prasun Panja, Paromita Roy, Navonil Desarkar, Sumit Gulati, Supriyo Ghatak, Shibajyoti Ghosh, Sudeep Banerjee, Bidyut Roy, Saurabh Ghosh, Dipankar Chaudhuri

Journal Articles

Background: Pancreatic Ductal Adenocarcinoma (PDAC) is a cancer of the exocrine pancreas and 5-year survival rates remain constant at 7%. Along with PDAC, Periampullary Adenocarcinoma (PAC) accounts for 0.5-2% of all gastrointestinal malignancies. Genomic observations were well concluded for PDAC and PACs in western countries but no reports are available from India till now. Methods: Targeted Next Generation Sequencing were performed in 8 (5 PDAC and 3 PAC) tumour normal pairs, using a panel of 412 cancer related genes. Primary findings were replicated in 85 tumour samples (31 PDAC and 54 PAC) using the Sanger sequencing. Mutations were also validated …

Retention Of Swine Slurry Constituents In Soil And Crop Residue As Affected By Setback Distance, John E. Gilley, Shannon L. Bartelt-Hunt, Kent M. Eskridge, Xu Li, Amy M. Schmidt, Daniel D. Snow

Department of Agricultural and Biological Systems Engineering: Faculty Publications

Setbacks are prescribed distances from surface waters within which manure application is not allowed. Little information is available concerning the retention of swine slurry constituents in soil and crop residue materials within setback areas. This study was conducted to measure the retention of selected constituents within a setback area following the upslope application of swine slurry and the introduction of simulated rainfall. The no-till cropland site had a slope gradient of 4.9% and a mean winter wheat residue cover of 7.73 Mg ha−1 . Soil and vegetative samples were collected on 3.7 m wide by 23.2 m long plots with …

Conversion Of Self-Contained Breathing Apparatus Mask To Open Source Powered Air-Purifying Particulate Respirator For Fire Fighter Covid-19 Response, Benjamin R. Hubbard, Joshua M. Pearce

Michigan Tech Publications, Part 1

To assist firefighters and other first responders to use their existing equipment for respiration during the COVID-19 pandemic without using single-use, low-supply, masks, this study outlines an open source kit to convert a 3M-manufactured Scott Safety self-contained breathing apparatus (SCBA) into a powered air-purifying particulate respirator (PAPR). The open source PAPR can be fabricated with a low-cost 3-D printer and widely available components for less than $150, replacing commercial conversion kits saving 85% or full-fledged proprietary PAPRs saving over 90%. The parametric designs allow for adaptation to other core components and can be custom fit specifically to fire-fighter equipment, including …

The Clinical Features Of Co-Circulating Dengue Viruses And The Absence Of Dengue Hemorrhagic Fever In Pakistan, Erum Khan, Dhani Prakoso, Kehkashan Imtiaz, Faisal Malik, Joveria Farooqi, Maureen T. Long, Kelli L. Barr

Department of Pathology and Laboratory Medicine

Dengue virus (DENV) is the most common and widespread arboviral infection worldwide. Though all four DENV serotypes cocirculate in nature, the clinicopathological framework of these serotypes is undefined in Pakistan. A cross-sectional, observational study was performed to document the circulation of various arboviruses in the Sindh region of Pakistan. Here we describe a population of patients diagnosed with DENV spanning a 2-year period. This study used an orthogonal system of NS1 antigen ELISA followed by RT-PCR for DENV detection and subtyping. A total of 168 NS1 positive patients were evaluated of which 91 patients were serotyped via RT-PCR. There was …

Longitudinal Predictors Of Helicopter Parenting In Emerging Adulthood, Laura M. Padilla-Walker, Larry J. Nelson, Ryan D. Mclean

Faculty Publications

The purpose of this exploratory longitudinal study was to examine stability and change of helicopter parenting throughout the first few years of emerging adulthood and to examine child and parent–child relational factors that might predict helicopter parenting. Participants included 453 emerging adults from a northwestern city in the United States (51% female, 33% single-parent families) who participated in a 10-year longitudinal study, with the current study examining ages 19–21. Results revealed that (a) for both mothers and fathers, helicopter parenting decreased over time, (b) some child and relational factors predicted initial levels of helicopter parenting, but (c) the findings were …

High Performance Computing Education: Current Challenges And Future Directions, Rajendra K. Raj, Carol J. Romanowski, John Impagliazzo, Sherif G. Aly, Brett A. Becker, Juan Chen, Sheikh Ghafoor, Nasser Giacaman, Steven I. Gordon, Cruz Izu, Shahram Rahimi, Michael P. Robson, Neena Thota

Computer Science: Faculty Publications

High Performance Computing (HPC) is the ability to process data and perform complex calculations at extremely high speeds. Current HPC platforms can achieve calculations on the order of quadrillions of calculations per second, with quintillions on the horizon. The past three decades witnessed a vast increase in the use of HPC across different scientific, engineering, and business communities on problems such as sequencing the genome, predicting climate changes, designing modern aerodynamics, or establishing customer preferences. Although HPC has been well incorporated into science curricula such as bioinformatics, the same cannot be said for most computing programs. Computing educators are only …

A Literature Review On Islamic Estate Planning From Year 2014 To 2019, Muhammad MuiʻZz Abdullah, Naimah Mohamad Nasir, Nasrul Hisyam Nor Muhamad, Muhammad Ridhwan Ab. Aziz, Abdul Bari Awang, Mek Wok Mahmud

Library Philosophy and Practice (e-journal)

A systematic property planning is one of the most important processes to ensure that the accumulated property over a person's lifetime can be fully utilized for goodness especially by their heirs. However, there are many problems of neglection and postponement in islamic estate distribution among the heirs nowadays, which result in difficulties in the management process. In fact, because of the unfamiliarity of the property distribution process among the heirs has caused them to ignore existing solutions. Therefore, this article aims to study the factors leading to delays in islamic estate administration and to highlight solutions to the arising issues …

Aptamer Hybrid Nanocomplexes As Targeting Components For Antibiotic/Gene Delivery Systems And Diagnostics: A Review, Navid Rabiee, Sepideh Ahmadi, Zeynab Arab, Mojtaba Bagherzadeh, Moein Safarkhani, Behzad Nasseri, Mohammad Rabiee, Mohammadreza Tahriri, Thomas J. Webster, Lobat Tayebi

School of Dentistry Faculty Research and Publications

With the passage of time and more advanced societies, there is a greater emergence and incidence of disease and necessity for improved treatments. In this respect, nowadays, aptamers, with their better efficiency at diagnosing and treating diseases than antibodies, are at the center of attention. Here, in this review, we first investigate aptamer function in various fields (such as the detection and remedy of pathogens, modification of nanoparticles, antibiotic delivery and gene delivery). Then, we present aptamer-conjugated nanocomplexes as the main and efficient factor in gene delivery. Finally, we focus on the targeted co-delivery of genes and drugs by nanocomplexes, …

Long-Term Ndvi And Recent Vegetation Cover Profiles Of Major Offshore Island Nesting Sites Of Sea Turtles In Saudi Waters Of The Northern Arabian Gulf, Rommel H. Maneja, Jeffrey D. Miller, Wenzhao Li, Hesham El-Askary, Ace Vincent B. Flandez, Joshua J. Dagoy, Joselito Francis A. Alcaria, Abdullajid U. Basali, Khaled A. Al-Abdulkader, Ronald A. Loughland, Mohamed A. Qurban

Mathematics, Physics, and Computer Science Faculty Articles and Research

Vegetation is an important ecological component of offshore islands in the Arabian Gulf (AG), which maintains long-term resilience of these islands. This is achieved by influencing sediment retention and moisture acquisition via condensation during periods of high humidity and by providing a variety of microhabitats for island fauna. The resilience of offshore islands’ ecosystems in the Saudi waters is important because they host the largest number of nesting hawksbill and green turtles in the AG. This study defines the characteristics and the long-term trends in vegetation cover of the offshore islands used by sea turtles as nesting grounds in the …

Feedback Between High-Pressure Genesis Of Abiotic Methane And Strain Localization In Subducted Carbonate Rocks, F Giuntoli, A Vitale Brovarone, L Menegon

School of Geography, Earth and Environmental Sciences

Fluid-rock interactions exert key control over rock rheology and strain localization. Redox may significantly affect the reaction pathways and, thereby, the mechanical properties of the rock. This effect may become critical in volatile-rich, redox sensitive rocks such as carbonate-rich lithologies, the breakdown of which can significantly modify the net volume change of fluid-mediated reactions. Subduction focus the largest recycling of crustal carbonates and the most intense seismic activity on Earth. Nevertheless, the feedbacks between deep carbon mobilization and deformation remain poorly investigated. We present quantitative microstructural results from natural samples and thermodynamic modeling indicating that percolation of reducing fluids exerts …

Studies On Transgenic Wheatgrass Of Exogenous Cbf4 Gene, Guihua Wang, Fugui Mi, Chunbo Xu, Shujun Dong

IGC Proceedings (1977-2023)

No abstract provided.

Overgrazing Affects Arbuscular Mycorrhizae Diversity And Abundance In Patagonian Steppe, Natalie Von Dudinszky, M. N. Cabello, A. A. Grimoldi, S. Schalamuk, R. A. Golluscio

IGC Proceedings (1977-2023)

No abstract provided.

Nature And The Environment In Amish Life—David Mcconnell And Marilyn Loveless, Steven Reschly, Scot Long, Caroline Brock

Journal of Amish and Plain Anabaptist Studies

In this symposium review, three agricultural and environmental researchers discuss the book Nature and the Environment in Amish Life by David McConnell and Marilyn Loveless, both of the College of Wooster in Wooster, Ohio. McConnell is an anthropology professor and co-author of Amish Paradox (2010, Johns Hopkins University Press) and has published his research in Human Organization, Anthropology and Education Quarterly, and the Journal of Amish and Plain Anabaptist Studies (JAPAS) (Moledina, et al. 2014). Loveless is a biology emeritus professor; this is her first academic publication about the Amish.

Our reviewers offer a variety of …