Digital Commons Network^™

Discovery Of A Novel Analogue Of Fr901533 And The Corresponding Biosynthetic Gene Cluster From Streptosporangium Roseum No. 79089, Fuchao Xu, Yonghong Liang, Jie Ren, Siyuan Wang, Jixun Zhan

Biological Engineering Faculty Publications

FR901533 (1, also known as WS79089B), WS79089A (2), and WS79089C (3) are polycyclic aromatic natural products with promising inhibitory activity to endothelin-converting enzymes. In this work, we isolated five tridecaketide products from Streptosporangium roseum No. 79089, including 1-3, benaphthamycin (4) and a novel FR901533 analogue (5). The structure of 5 was characterized based on spectroscopic data. Compared to the major product 2, the new compound 5 has an additional hydroxyl group at C-12 and an extra methyl group at the 13-OH. The configuration of C-19 of these compounds …

The Culture Of Learning Disabilities, Race And Athletics: An Examination Of Student-Athlete Experiences In Predominantly White Institutions Of Higher Education’S Division One College Football Programs, Ashley L. White

USF Tampa Graduate Theses and Dissertations

Students’ educational experiences vary. The differences in these experiences can be attributed to a variety of factors, including but not limited to geographic location, socio-economic status, age, gender, race, ability, and individual experiences before and during schooling. In this study, the researcher examined the intersectionality of race and disability in the context of postsecondary education and student-athletes through the experiences of participants who identified themselves within select categories, namely as Black/African American and student-athlete. Of equal importance, participants struggled to meet normalized standards of learning during their P-12 educational experiences and/or were identified with a categorical learning disability. As will …

Metformin Enhances Autophagy And Normalizes Mitochondrial Function To Alleviate Aging-Associated Inflammation, Leena P Bharath, Madhur Agrawal, Grace Mccambridge, Dequina A Nicholas, Hatice Hasturk, Jing Liu, Kai Jiang, Rui Liu, Zhenheng Guo, Jude Deeney, Caroline M Apovian, Jennifer Snyder-Cappione, Gregory S Hawk, Rebecca M Fleeman, Riley M F Pihl, Katherine Thompson, Anna C Belkina, Licong Cui, Elizabeth A Proctor, Philip A Kern, Barbara S Nikolajczyk

Faculty, Staff and Student Publications

Age is a non-modifiable risk factor for the inflammation that underlies age-associated diseases; thus, anti-inflammaging drugs hold promise for increasing health span. Cytokine profiling and bioinformatic analyses showed that Th17 cytokine production differentiates CD4+ T cells from lean, normoglycemic older and younger subjects, and mimics a diabetes-associated Th17 profile. T cells from older compared to younger subjects also had defects in autophagy and mitochondrial bioenergetics that associate with redox imbalance. Metformin ameliorated the Th17 inflammaging profile by increasing autophagy and improving mitochondrial bioenergetics. By contrast, autophagy-targeting siRNA disrupted redox balance in T cells from young subjects and activated the Th17 …

Insights In The Global Genetics And Gut Microbiome Of Black Soldier Fly, Hermetia Illucens: Implications For Animal Feed Safety Control, Fathiya M. Khamis, Fidelis L.O. Ombura, Komivi S. Akutse, Sevgan Subramanian, Samira A. Mohamed, Komi K.M. Fiaboe, Weerachai Saijuntha, Joop J.A. Van Loon, Marcel Dicke, Thomas Dubois, Sunday Ekesi, Chrysantus M. Tanga

All Peer-Reviewed Publications

The utilization of the black soldier fly (BSF) Hermetia illucens L. for recycling organic waste into high-quality protein and fat biomass for animal feeds has gained momentum worldwide. However, information on the genetic diversity and environmental implications on safety of the larvae is limited. This study delineates genetic variability and unravels gut microbiome complex of wild-collected and domesticated BSF populations from six continents using mitochondrial COI gene and 16S metagenomics. All sequences generated from the study linked to H. illucens accessions KM967419.1, FJ794355.1, FJ794361.1, FJ794367.1, KC192965.1, and KY817115.1 from GenBank. Phylogenetic analyses of the sequences generated from the study and …

Key Strategic Issues List (Ksil) 2021–2022, Steve Cunningham

Books, Monographs & Collaborative Studies

New for Academic Years 2021-2022, the USAWC has published an updated Key Strategic Issues List (KSIL). The KSIL informs students, faculty, and external research associates of strategic topics requiring research and analysis. The USAWC in coordination with Headquarters Department of the Army (HQDA), major commands throughout the Army, and the joint and interagency community has updated the Army's priorities for strategic analysis to address issues in the emerging strategic environment and to align with elements of the current Army Vision and Army Strategy. The USAWC will continue to address select topics as Integrated Research Projects and through other research efforts. …

Co-Firing Of Rice Straw And Natural Gas In Fluidized Bed Furnace., G. Zaater, S. El-Emam, M. Awad, F. Okasha

Mansoura Engineering Journal

Experimental study on co-cofiring of rice straw and natural gas has been performed in a fluidized bed. The used combustor allows the novel, jetting-fountain configuration and the conventional operation as well. The experimental apparatus is mainly a bubbling fluidized bed of 300 mm ID and 3300 mm height equipped with a 38.1 mm ID jet-pipe located at the combustor center. In jetting-fountain configuration, natural gas premixed with the air required for its combustion proceeds through the jet pipe to create jet-fountain zone. Whereas only the air required for rice straw combustion passes through a gas distributor. The findings of the …

Convivial Acts For An Ecosensual Labyrinth, Helen Billinghurst, Phil Smith

School of Art, Design and Architecture

No abstract provided.

Characteristic Of Gas Exchange And Chlorophyll Fluorescence Parameters In Leaves Of Lespedeza Davurica, Dong Lin, Huiling Ma, Shihai Lu, Chaoyang Feng

IGC Proceedings (1977-2023)

No abstract provided.

Plant Regeneration From In Vitro Stem Explants Of Dianthus Spiculifolius, Yanping Liang, Yan Sun, Qingchuan Yang

IGC Proceedings (1977-2023)

No abstract provided.

Pattern Of Nitrogen Integration And Its Ecological Implications In Clonal Plant Zoysia Japonica, Dezhi Li, Changai Wang

IGC Proceedings (1977-2023)

No abstract provided.

Maternal Love Shown Through Punishment, Megan Donaty

Parnassus: Classical Journal

No abstract provided.

Parnassus: Classical Journal (Volume 7, 2020)

Parnassus: Classical Journal

No abstract provided.

Trophic Interactions And Habitat Quality Of Invasive Lionfish In The Gulf Of Mexico, Hanna Bauer

LSU Master's Theses

Lionfish (Pterois volitans and Pterois miles) are one of the most successful marine invaders of all time and pose a threat to native species that inhabit coral reefs, as well as overall reef health. Current management efforts in the invaded Atlantic region revolve around spearfishing to remove lionfish, often limited to 30 m depth. There is evidence that lionfish may seek refuge from fishing pressure in deeper habitat and replenish shallow sites, undermining this management strategy. To investigate the ecological implications of deep lionfish, size, reproductive capability, and diet were examined across a depth gradient for lionfish in …

Identification And Quantification Of Microplastic Pollution In Water Samples And Four Species Of Fish From The Mississippi River, Kerrin E. Toner

LSU Master's Theses

Microplastics (£5 mm) have become a persistent anthropogenic pollutant and a growing environmental concern with evidence of them being found throughout several ecosystems. In recent years, there has been a growing recognition that rivers play a major role in transporting plastics from the land to the sea. The Mississippi River is the largest river in North America, draining land populated by over 100 million people. With high numbers of microplastics found in the waters of the northern of the Gulf of Mexico, it is likely that the Mississippi River is the primary source of these plastics. This study quantifies and …

Southwest Pacific Tropical Cyclone Frequency And Intensity Related To Observed And Modeled Geophysical And Aerosol Variables, Rupsa Bhowmick

LSU Doctoral Dissertations

The dissertation focuses on western region of Southwest Pacific Ocean (SWPO)

basin (135E - 180, and 5S - 35S) tropical cyclone (TC) climatology using observed

and modeled data. The classification-based machine learning approach

identifies the synoptic geophysical and aerosol environment favorable or unfavorable

for TC intensification and intensity change prior to landfall incorporating

observational and satellite data. A multiple poisson regression model with varying

temporal monthly lags was used to build a relationship between the number of

monthly TC days with basin wide average dust aerosol optical depth (AOD), sea

surface temperature (SST), and upper ocean temperature (UOT). This idea …

Summed Batch Lexicase Selection On Software Synthesis Problems, Joseph Deglman

Scholarly Horizons: University of Minnesota, Morris Undergraduate Journal

Lexicase selection is one of the most successful parent selection methods in evolutionary computation. However, it has the drawback of being a more computationally involved process and thus taking more time compared to other selection methods, such as tournament selection. Here, we study a version of lexicase selection where test cases are combined into several composite errors, called summed batch lexicase selection; the hope being faster but still reasonable success. Runs on some software synthesis problems show that a larger batch size tends to reduce the success rate of runs, but the results are not very conclusive as the number …

Effect Of Different Culture Medium On Subculture And Differentiation Of Alfalfa Anther Callus, Zenghong Li, Bo Zhang, Aiping Chen, Yupeng Luo

IGC Proceedings (1977-2023)

No abstract provided.

Physiological Response To Soil Drought Stress For Two Ornamental Grasses, Lanjing Kong, Zhiguo Zhang

IGC Proceedings (1977-2023)

No abstract provided.

Spatial Distribution, Biomass, And Soil Seed Bank Of A Naturalized Population Of Alfalfa In Native Mixed-Grass Prairie, Lan Xu, A. Boe, R. N. Gates, P. S. Johnson, Y. Zhang

IGC Proceedings (1977-2023)

No abstract provided.

Genetic Polymorphism By Rapd Of Leymus Chinensis, X. J. Kong, Z. W. Liang, M. Liu, H. Y. Ma

IGC Proceedings (1977-2023)

No abstract provided.

Changes In Plant Communities By Grazing In Northern Mongolian Grassland And Assessment Of Nomads, K. Kakinuma, S. Takatsuki

IGC Proceedings (1977-2023)

No abstract provided.

Blended Learning Showing Gains, Jessica Lynn Becker

Graduate Teacher Education

In light of what is known about how children learn and the use of technology in society, blended learning is proving to be an effective teaching strategy to improve student academic achievement. Blended learning is a combination of digital technology with face-to-face direct instruction. The purpose of blended learning instruction is to combine the benefits of face-to-face direct instruction with the personalization and collaboration of digital technology. Blended learning comes in many different models that meet the many needs of teachers and school districts. It has succeeded in improving student academic achievement in different subject areas by allowing students to …

Contrasting Effects Of Climate Change On Seasonal Survival Of A Hibernating Mammal, Lina S. Cordes, Daniel T. Blumstein, Kenneth B. Armitage, Paul J. Caradonna, Dylan Z. Childs, Brian Gerber, Julien Ga Martin, Madan K. Oli, Arpat Ozgul

Natural Resources Science Faculty Publications

Seasonal environmental conditions shape the behavior and life history of virtually all organisms. Climate change is modifying these seasonal environmental conditions, which threatens to disrupt population dynamics. It is conceivable that climatic changes may be beneficial in one season but result in detrimental conditions in another because life-history strategies vary between these time periods. We analyzed the temporal trends in seasonal survival of yellow-bellied marmots (Marmota flaviventer) and explored the environmental drivers using a 40-y dataset from the Colorado Rocky Mountains (USA). Trends in survival revealed divergent seasonal patterns, which were similar across age-classes. Marmot survival declined during …

Observation Of The Low-Frequency Spectrum Of The Water Trimer As A Sensitive Test Of The Water-Trimer Potential And The Dipole-Moment Surface, Raffael Schwan, Chen Qu, Devendra Mani, Nitish Pal, Gerhard Schwaab, Joel M. Bowman, Gregory S. Tschumper, Martina Havenith

Faculty and Student Publications

© 2020 The Authors. Published by Wiley-VCH Verlag GmbH & Co. KGaA. Intermolecular interactions in bulk water are dominated by pairwise and non-pairwise cooperative interactions. While accurate descriptions of the pairwise interactions are available and can be tested by precise low-frequency spectra of the water dimer up to 550 cm−1, the same does not hold for the three-body interactions. Here, we report the first comprehensive spectrum of the water trimer in the frequency region from 70 to 620 cm−1 using helium-nanodroplet isolation and free-electron lasers. By comparison to accompanying high-level quantum calculations, the experimentally observed intermolecular bands can be assigned. …

Seeking The Feminine Divine: Mormon Women's Religious Authority, Power, And Presence In Rachel Hunt Steenblik's Mother's Milk, Kaitlin Hoelzer

Undergraduate Honors Theses

Literary theorists like Hélène Cixous and other French feminists have written about l’écriture feminine, a deconstructive force which allows female writers more freedom from male-dominated areas. Because Christianity has been historically male-dominated, Christian women have long used this idea to great effect, using their writing as a space in which they are free to assert power and authority. Mormonism, which arose in the 1830s during the Second Great Awakening, has grown to reinforce a patriarchal model for both family and church leadership, making Cixous’ separate space of writing necessary for Mormon women of the twenty-first century. The Mormon poet …

In Vitro Digestibility Of Mountain-Grown Irrigated Perennial Legume, Grass And Forb Forages Is Influenced By Elevated Non-Fibrous Carbohydrates And Plant Secondary Compounds, Yunhua Zhang, Jennifer W. Macadam, Juan J. Villalba, Xin Dai

Plants, Soils, and Climate Faculty Publications

BACKGROUND

Perennial legumes cultivated under irrigation in the Mountain West USA have non‐fibrous carbohydrate (NFC) concentrations exceeding 400 g kg−1, a level commonly found in concentrate‐based ruminant diets. Our objective was to determine the influence of NFC concentration and plant secondary compounds on in vitro rumen digestion of grass, legume and forb forages compared with digestion of their isolated neutral detergent fiber (NDF) fraction. Forages were composited from ungrazed paddocks of rotationally stocked, irrigated monoculture pastures between May and August 2016, frozen in the field, freeze‐dried, and ground.

RESULTS

The maximum rate (RMax) of gas production was greater for the …

The Lived Experiences Of Male Partners Of Women Who Have Previously Been Diagnosed With Postpartum Depression, Judy Kaye Smith

Dissertations

This qualitative, descriptive phenomenological study was conducted to determine the actual lived experiences of male partners of women who have previously been diagnosed with postpartum depression. The study also explored the knowledge level of male partners with regard to the phenomenon of postpartum depression. While experiences were varied, three common themes emerged of being vulnerable, being helpless, and coping with two to four sub-themes identified under each one. The seven men who participated demonstrated gaps in the knowledge with regard to the phenomenon of postpartum depression.

Sunken Efforts? Legal Hurdles To Stemming Maritime Cbrne Proliferation, Arjun Banerjee

International Journal of Nuclear Security

For four centuries, the law of the sea has rested on the principle of mare liberum or the freedom of the high seas. The oceans have traditionally been regarded as areas over which no state could claim dominion or sovereignty. Nations desirous of countering security threats have found that their efforts are curtailed by the traditional paradigm, partly because of the resistance from other states to permit further derogation. Several extant laws aim to contain the spread of CBRN (chemical, biological, radiological and nuclear) material through a variety of measures. Certain bilateral agreements between nations exist, but the foreign vessel …

Foundational Research And Nih Funding Enabling Emergency Use Authorization Of Remdesivir For Covid-19, Ekaterina Galkina Cleary, Matthew J. Jackson, Zoë Folchman-Wagner, Fred D. Ledley

Natural & Applied Sciences Faculty Publications

Emergency Use Authorization for remdesivir months after discovery of COVID-19 is unprecedented. Typically, decades of research and public-sector funding are required to establish the mature body of foundational research requisite for efficient, targeted drug discovery and development. This work quantifies the body of research related to remdesivir’s biological target, RNA-dependent RNA polymerase (RdRp), or parent chemical structure, nucleoside analogs (NcAn), through 2019, as well as NIH funding for this research 2000–2019. There were 6,567 RdRp-related publications in PubMed, including 1,263 with NIH support, and 11,073 NcAn-related publications, including 2,319 with NIH support. NIH support for RdRp research comprised 2,203 Project …

Illinois Mathematics And Science Academy: Reunión Nacional De Profesores Prepatec 2020, José M. Torres

Keynotes, Speeches, and Lectures

LEGISLATIVE MANDATE 1

The primary role of the Academy shall be to offer a challenging education for students talented in the areas of mathematics and science.

LEGISLATIVE MANDATE 2

The Academy shall also carry a responsibility to stimulate further excellence for all Illinois schools in mathematics and science.