Digital Commons Network^™

The Joy Of Specs, Sarah Scaier

UNH Today Archive

No abstract provided.

The Historic Fire Return Interval And The Ecological Effects Of Fire Suppression On Montane Longleaf Pine Dominated Ecosystems In Northwestern Georgia., Christopher Waters

Master of Science in Integrative Biology Theses

Longleaf pine ecosystems have experienced pronounced declines across the southeastern United States since Euro-American settlement took place in the late 19th century. These declines were primarily caused by federal fire suppression policies implemented in the 1920’s, in combination with resource harvesting and land use conversion. In an absence of fire, tree species composition of frequently burned xeric ecosystems progressively becomes more mesic and fire-intolerant (i.e. mesophication). The change in the species composition and historic fire frequency of a montane longleaf pine ecosystem located in Sheffield Wildlife Management Area (WMA), Paulding County, Georgia was investigated. The change in forest composition …

Epidemiology Of Cancers In Men Who Have Sex With Men (Msm): A Protocol For Umbrella Review Of Systematic Reviews, Manoj Kumar Honaryar, Yelena Tarasenko, Maribel Almonte, Vitaly Smelov

Biostatistics, Epidemiology & Environmental Health Sciences: Faculty Publications

While earlier studies on men having sex with men (MSM) tended to examine infection-related cancers, an increasing number of studies have been focusing on effects of sexual orientation on other cancers and social and cultural causes for cancer disparities. As a type of tertiary research, this umbrella review (UR) aims to synthesize findings from existing review studies on the effects of sexual orientation on cancer. Relevant peer-reviewed systematic reviews (SRs) will be identified without date or language restrictions using MEDLINE, Cochrane Database of Systematic Reviews, and the International Prospective Register for Systematic Reviews, among others. The research team members will …

Facilitators And Barriers To Treatment Engagement In A Behavioral Parent Training Program, Holland Hayford

USF Tampa Graduate Theses and Dissertations

This quantitative study sought to analyze caregivers’ perspectives regarding facilitators of, and barriers to, attending the behavioral parent training programs (BPTs) known as Helping Our Toddlers, Developing Our Children’s Skills (HOT DOCS) and Developing Our Children’s Skills K-5 (DOCS K-5). Participants included 43 caregivers who successfully completed their respective DOCS program. These caregivers answered two questionnaires which contained items addressing demographic variables (i.e., gender, race, ethnicity, household income, level of education, number of children, and program attendance) and logistic factors of the DOCS programs (i.e., course location, class length, time of day, course duration, availability of transportation, availability of childcare). …

Jumping Into The River, Allison Brace

Materials from the University of Dayton Magazine Website

Senior River Stewards wrote, illustrated and designed a picture book, taking readers on a colorful journey through the Great Miami River.

Anatomical Organization And Distinction Of The Sympathetic Inputs To Interscapular Brown Adipose Tissue And Inguinal White Adipose Tissue In The Mouse, Clara Jane Huesing

LSU Doctoral Dissertations

Adipose tissue is a dynamic endocrine organ that contains both the problem and the solution to discovering new therapies for individuals with obesity. Excessive adipose tissue disrupts energy balance and causes a host of comorbidities like insulin resistance and hypertension. On the other hand, adipose tissue is essential for life. During periods of energy demand, sympathetic nerve activity in brown and white adipose tissue stimulates thermogenesis and lipolysis; both of which decrease body weight and improve metabolic health. Therefore, comprehensive insight into the organization of sympathetic innervation and how it communicates with adipocytes is critical in order to utilize its …

Treatment Of Oil And Grease In Wastewater Using Electrocoagulation., Hisham El-Etriby, Kamal Radwan, Karim Taha

Mansoura Engineering Journal

Batch electrocoagulation (EC) experiments were carried out to evaluate the removal of COD and O&G from wastewater using two types of electrodes: aluminum, iron, and then mix of aluminum and iron. The effects of operating parameters such as current intensity, initial COD concentration, contact time and NaCl concentration on COD and O&G removal efficiency had been investigated. It was found that increasing current intensity increased COD and O&G removal efficiency. Initial COD concentration had a little effect on removal efficiencies. Results showed that the best performance was obtained using aluminum electrode at a current intensity of 1.3 Ampere and 11.6 …

Allosteric Regulation At The Crossroads Of New Technologies: Multiscale Modeling, Networks, And Machine Learning, Gennady M. Verkhivker, Steve Agajanian, Guang Hu, Peng Tao

Mathematics, Physics, and Computer Science Faculty Articles and Research

Allosteric regulation is a common mechanism employed by complex biomolecular systems for regulation of activity and adaptability in the cellular environment, serving as an effective molecular tool for cellular communication. As an intrinsic but elusive property, allostery is a ubiquitous phenomenon where binding or disturbing of a distal site in a protein can functionally control its activity and is considered as the “second secret of life.” The fundamental biological importance and complexity of these processes require a multi-faceted platform of synergistically integrated approaches for prediction and characterization of allosteric functional states, atomistic reconstruction of allosteric regulatory mechanisms and discovery of …

An Investigation Of Gene Regulatory Network State Space Variability, Sara Faye Liesman

Theses and Dissertations

Genes are segments of DNA that provide a blueprint for cells and organisms to effectively control processes and regulations within individuals. There have been many attempts to quantify these processes, as a greater understanding of how genes operate could have large impacts on both personalized and precision medicine. Gene interactions are of particular interest, however, current biological methods can not easily reveal the details of these interactions. Therefore, we infer networks of interactions from gene expression data which we call a gene regulatory network, or GRN. Due to the robust behavior of genes and the inherent variability within interactions, models …

A Practical Guide For Managing Interdisciplinary Teams: Lessons Learned From Coupled Natural And Human Systems Research, V. Reilly Henson, Kelly M. Cobourn, Kathleen C. Weathers, Cayelan C. Carey, Kaitlin J. Farrell, Jennifer L. Klug, Michael G. Sorice, Nicole K. Ward, Weizhe Weng

School of Business

Interdisciplinary team science is essential to address complex socio-environmental questions, but it also presents unique challenges. The scientific literature identifies best practices for high-level processes in team science, e.g., leadership and team building, but provides less guidance about practical, day-to-day strategies to support teamwork, e.g., translating jargon across disciplines, sharing and transforming data, and coordinating diverse and geographically distributed researchers. This article offers a case study of an interdisciplinary socio-environmental research project to derive insight to support team science implementation. We evaluate the project’s inner workings using a framework derived from the growing body of literature for team science best …

Perfusion-Guided Sonopermeation Of Neuroblastoma: A Novel Strategy For Monitoring And Predicting Liposomal Doxorubicin Uptake, Aditi Bellary, Arelly Villarreal, Rojin Eslami, Quincy J Undseth, Bianca Lec, Ann M Defnet, Naina Bagrodia, Jessica J Kandel, Mark A Borden, Sumbul Shaikh, Rajiv Chopra, Theodore W Laetsch, Lauren J. Delaney, Colette Shaw, Md, John R. Eisenbrey, Sonia L Hernandez, Shashank R Sirsi

Department of Radiology Faculty Papers

Neuroblastoma (NB) is the most common extracranial solid tumor in infants and children, and imposes significant morbidity and mortality in this population. The aggressive chemoradiotherapy required to treat high-risk NB results in survival of less than 50%, yet is associated with significant long-term adverse effects in survivors. Boosting efficacy and reducing morbidity are therefore key goals of treatment for affected children. We hypothesize that these may be achieved by developing strategies that both focus and limit toxic therapies to the region of the tumor. One such strategy is the use of targeted image-guided drug delivery (IGDD), which is growing in …

Whole Genome Sequencing Of Four Representatives From The Admixed Population Of The United Arab Emirates, Gihan Daw Elbait, Andreas Henschel, Guan K. Tay, Habiba S. Al Safar

Research outputs 2014 to 2021

© Copyright © 2020 Daw Elbait, Henschel, Tay and Al Safar. Whole genome sequences (WGS) of four nationals of the United Arab Emirates (UAE) at an average coverage of 33X have been completed and described. The selection of suitable subpopulation representatives was informed by a preceding comprehensive population structure analysis. Representatives were chosen based on their central location within the subpopulation on a principal component analysis (PCA) and the degree to which they were admixed. Novel genomic variations among the different subgroups of the UAE population are reported here. Specifically, the WGS analysis identified 4,161,067–4,798,806 variants in the four individual …

Proteogenomic Characterization Reveals Therapeutic Vulnerabilities In Lung Adenocarcinoma, Michael A. Gillette, Song Cao, Yize Li, Wen-Wei Liang, Michael C Wendl, Ramaswamy Govindan, Et Al.

2020-Current year OA Pubs

To explore the biology of lung adenocarcinoma (LUAD) and identify new therapeutic opportunities, we performed comprehensive proteogenomic characterization of 110 tumors and 101 matched normal adjacent tissues (NATs) incorporating genomics, epigenomics, deep-scale proteomics, phosphoproteomics, and acetylproteomics. Multi-omics clustering revealed four subgroups defined by key driver mutations, country, and gender. Proteomic and phosphoproteomic data illuminated biology downstream of copy number aberrations, somatic mutations, and fusions and identified therapeutic vulnerabilities associated with driver events involving KRAS, EGFR, and ALK. Immune subtyping revealed a complex landscape, reinforced the association of STK11 with immune-cold behavior, and underscored a potential immunosuppressive role of neutrophil degranulation. …

Collaborative, Multidisciplinary Evaluation Of Cancer Variants Through Virtual Molecular Tumor Boards Informs Local Clinical Practices, Shruti Rao, Beth Pitel, Alex H Wagner, Simina M Boca, Matthew Mccoy, Ian King, Samir Gupta, Ben Ho Park, Jeremy L Warner, James Chen, Peter K Rogan, Debyani Chakravarty, Malachi Griffith, Obi L Griffith, Subha Madhavan

2020-Current year OA Pubs

PURPOSE: The cancer research community is constantly evolving to better understand tumor biology, disease etiology, risk stratification, and pathways to novel treatments. Yet the clinical cancer genomics field has been hindered by redundant efforts to meaningfully collect and interpret disparate data types from multiple high-throughput modalities and integrate into clinical care processes. Bespoke data models, knowledgebases, and one-off customized resources for data analysis often lack adequate governance and quality control needed for these resources to be clinical grade. Many informatics efforts focused on genomic interpretation resources for neoplasms are underway to support data collection, deposition, curation, harmonization, integration, and analytics …

Lessening The Hazards Of Florida Red Tides: A Common Sense Approach, Porter Hoagland, Barbara Kirkpatrick, Di Jin, Gary Kirkpatrick, Lora E. Fleming, Steven G. Ullmann, Andrew Beet, Gary Hitchcock, Kate K. Harrison, Zongchao C. Li, Bruce Garrison, Roberto E. Diaz, Vince Lovko

Faculty Research, Scholarly, and Creative Activity

In the Gulf of Mexico, especially along the southwest Florida coast, blooms of the dinoflagellate Karenia brevis are a coastal natural hazard. The organism produces a potent class of toxins, known as brevetoxins, which are released following cell lysis into ocean or estuarine waters or, upon aerosolization, into the atmosphere. When exposed to sufficient levels of brevetoxins, humans may suffer from respiratory, gastrointestinal, or neurological illnesses. The hazard has been exacerbated by the geometric growth of human populations, including both residents and tourists, along Florida’s southwest coast. Impacts to marine organisms or ecosystems also may occur, such as fish kills …

By Your Powers Combined: Heroic Solutions To Climate Catastrophes In The Fifth Season, Avengers: Infinity War, And Horizon: Zero Daw N, Kematat Matthew Medrala

Theses and Dissertations

Popular entertainment has become concerned with addressing issues of climate catastrophe in order to reflect the real concerns of its audience. Because these media narratives are produced by wealthy institutions that reach millions of people, it is vital to understand what these stories say about the causes of existential crises and their presented solutions. This thesis applies an ecocritical approach informed by environmental justice theorists and Marxist theory in order to analyze what a contemporary popular film, videogame, and novel have to say about addressing an oncoming ecological crisis. This analysis reveals that mass death among the disempowered is considered …

Investigating The Regulation And Role Of P38 Mapk In Collagen-Related Limb Girdle Muscular Dystrophy, Briseida Oceguera-Perez

Theses and Dissertations

Aging is an expected and normal process across living organisms. It is characterized as a loss of stress resistance, degeneration of tissues, and decline in motor function that happen gradually across lifespan. Susceptibility to neurodegenerative and dystrophic conditions also increase, and unlike aging, are not a normal aspect of lifespan. Discerning the difference between normal and aberrant aging states will give insight into the mechanisms behind the progressive dysfunction shared among organisms. Previous work in our lab has shown that the aging gene p38 MAPK in Drosophila melanogaster plays a significant role in the aging process through its downstream effects …

Project-Based Learning Instruction For A Student With Disabilities: Experiences Of A Student And Teachers, Robert C. Shauger

Special Education ETDs

Students with disabilities have been underrepresented in research examining the implementation of project-based learning (PBL) instruction. This qualitative case study described the experiences of a student with a disability in an inclusive classroom where teachers used PBL instruction. I used interviews, observations, audio recorded conversations in class, and analyzed teacher-created curriculum documents and student artifacts. Thematic analysis generated four primary themes including: Supporting students, student buy-in, teacher and student interactions in PBL are complex, and student demonstration of learning. Recommendations for classroom practice to support students with disabilities in PBL instruction included extensive teacher collaboration, individualized instruction, and teaching students …

Forging Our Future: A Review Of The Synthetic Age, Jeff Ploegstra

Faculty Work Comprehensive List

"Part of Preston’s argument is for a profound improvement in scientific fluency in the population, but it should also be for a stronger behavioral response as well."

Posting about ­­­­­­­­the book The Synthetic Age from In All Things - an online journal for critical reflection on faith, culture, art, and every ordinary-yet-graced square inch of God’s creation.

https://inallthings.org/forging-our-future-a-review-of-the-synthetic-age/

Character Of Canopy Apparent Photosynthesis And Transpiration In Seriphidium Semidesert Under Different Degradation Gradient, W. H. Lu, J. Z. Zhu, G. L. Jin, D. J. Wang, H. L. Liu

IGC Proceedings (1977-2023)

No abstract provided.

Study On Amf In Rhizosphere Of Vetiver Grass In Field Nursery, Lixia Gao, Xuhui Kong, Yu Chen, Chonglu Zhong

IGC Proceedings (1977-2023)

No abstract provided.

Studies On Root Turion Propagation Technology Of Wild Hazelnut In Daxing'anling, China, Yuliang Liu, Fugui Mi, Puchang Wang

IGC Proceedings (1977-2023)

No abstract provided.

Research On Community Dominance And Functional Groups After Sandy Land Enclosed, Yan Liu, Fengling Shi, Bo Zhao, Ying Liu, Xiaohong Wang

IGC Proceedings (1977-2023)

No abstract provided.

Forage‐Livestock Industry Is A Fundamental Issue For Ecologic And Economic Win‐Win In The Loess Plateau, China, Xiuqin Liu, Zihe Zhang

IGC Proceedings (1977-2023)

No abstract provided.

A Review Of Xinjiang And The Modern Chinese State, Andres Freeman

History in the Making

No abstract provided.

A War From Within: An Analysis Of The Factors That Caused The Collapse Of The Iroquois Confederacy, Jessica Howe

History in the Making

This report hopes to answer the question, how and why one of the most powerful and long lasting Native American Confederacy collapsed during the Revolutionary War? This paper investigates how the economy, diplomatic disunification, and the deterioration of traditional religious beliefs through Christianity caused the Iroquois Confederacy to crumble. Although many others have attempted to answer this question, this research is different in that it relies heavily upon both historical and anthropological sources providing it with a unique interdisciplinary perspective. Furthermore, the specific context of this paper is also distinctive and is supported by primary and secondary sources. The narrow …

Six New Species Of Orthochirus Karsch, 1892 From Iran (Scorpiones: Buthidae), František Kovařík, Shahrokh Navidpour

Euscorpius

Six new scorpion species from Iran, Orthochirus hormozganensis sp. n. (Hormozgan Province), O. kermanensis sp. n. (Kerman Province), O. kucerai sp. n. (Kerman Province), O. masihipouri sp. n. (Bushehr Province), O. semnanensis sp. n. (Semnan Province), and O. vignolii sp. n. (Yazd Province) are described, compared with other Iranian Orthochirus species, and fully illustrated with color photographs. A key and a distribution map of Orthochirus of Iran, Turkey, and Iraq (18 species) are included.

Anti-Black Racism And White Supremacy Soc/Apg 140x, Karen Morse

Library Impact Statements

No abstract provided.

The Strengths, Weaknesses, Opportunities And Threats (Swot) Analysis Of The Severe Acute Respiratory Syndrome Coronavirus 2 Of Covid-19, Michael Oluyemi Babalola Ph.D

The University of Louisville Journal of Respiratory Infections

Introduction: SARS-CoV-2 is the etiologic agent of Coronavirus Disease 2019 (COVID-19), a highly contagious, emergent, acute, viral pneumonia that emanated sporadically in Wuhan, China, in December 2019. COVID-19 became a pandemic in February 2020, leading to 4,942,687 confirmed cases and over 321,987 deaths and grounding several economies around the world as of May 2020. Although global researchers, epidemiologists, virologists, and medical professionals rose steadily to contain the disease, in-depth knowledge of the virus and concerted efforts to combat it are still evolving. This research sought to elucidate the biological Strengths, Weaknesses, Opportunities, and Threats to SARS-CoV-2, with a view to …

Improving Clinician Adherence Rates To Aims Testing On Individuals Taking Long-Term Antipsychotics, Shavaun Johnson

Dissertations

Abstract

Problem: Tardive dyskinesia is a common problem that creates challenges in the lives of those affected by it. The Abnormal Involuntary Movement Scale records the occurrence of tardive dyskinesia in patients receiving neuroleptic medication. With this scale, clinicians can detect tardive dyskinesia and its severity over time. The aim of this study is to learn the current rate of adherence for clinicians at the organization and to create and implement an intervention that will increase that rate in an effort to improve patient outcomes and quality of life.

Methods: This quality improvement project will use a descriptive cohort …