Digital Commons Network^™

Pediatric Sjs-Ten: Where Are We Now?, Michele Ramien, Jennifer Goldman

Manuscripts, Articles, Book Chapters and Other Papers

Stevens-Johnson syndrome and toxic epidermal necrolysis are rare severe blistering skin reactions triggered by medications or infections. Over the last 5 to 10 years, a number of important publications have advanced understanding of these diseases and their response to treatment. Importantly, a subset of patients with disease triggered by infection has been identified as having Mycoplasma pneumoniae-induced rash and mucositis, suggesting a reconsideration of the diagnostic paradigm. We present an update on pediatric Stevens-Johnson syndrome and toxic epidermal necrolysis in the broader context of cutaneous adverse drug reactions and focus on challenges and recent advances in diagnosis, management, and prevention.

Effect Of Azospirillum On Fodder Production In The Semi‐Arid Region Of South India, J. Sebastinraj, K. Mahoharan, Kailash Paliwal

IGC Proceedings (1977-2023)

No abstract provided.

Does Pre‐Existing Vegetation Make A Difference For Re‐Establishing Native Shrubs?, Michael P. Schellenberg, J. C. Perez, D. Henderson, John F. Wilmshurst

IGC Proceedings (1977-2023)

No abstract provided.

Free Amino Acids Content And Nitrogen Mobilization In Panicum Maximum, Patricia M. Santos, J. A. Bendolassi, Rodolfo Godoy

IGC Proceedings (1977-2023)

No abstract provided.

Response Of An Improved Pasture To Different Phosphoric Fertilisation Strategies In Basaltic Soils, D. F. Risso, R. Cuadro, A. Morón

IGC Proceedings (1977-2023)

No abstract provided.

Ronald E. Mcnair Scholars Program Profiles And Abstracts 2020, Mcnair Scholars Program

McNair Symposium

This is the complete event program and provides presentation abstracts and biographies of McNair scholars and their mentors.

Sex Modifies The Association Between The Clock Variant Rs1801260 And Bmi In School-Age Children, Ying Meng, Barbara Lohse, Leslie Cunningham-Sabo

Articles

Disruption of circadian rhythms and variations in the FTO gene may interfere with energy homeostasis and play a role in the development of obesity. The current study assessed the association of common polymorphisms in the CLOCK and FTO genes with standardized body mass index scores (BMI z-scores) and their potential modification of the impact of a culinary nutrition and physical activity intervention in school-age children. Anthropometric measurements were collected in 121 children at the baseline and one-year follow-up of a controlled trial of a school-based culinary nutrition and physical activity intervention. Genotypes of the CLOCK polymorphism (rs1801260) and the FTO …

Medical Treatment Of Diabetes Compared To Bariatric Surgery, Daniel Thornley

Theses and Graduate Projects

In this retrospective review, metabolic factors present in diabetic patients who underwent bariatric surgery were compared against those who were treated with medical therapy alone. These factors include: diabetes remission, glycosylated hemoglobin levels, medication use, changes in beta cells function, insulin sensitivity, incretin levels, weight loss, lipid profiles and blood pressures. Following bariatric surgery, patients observed superior changes in diabetes remission rates, glycosylated hemoglobin levels, medication use, beta cell function, insulin sensitivity, incretin levels, and weight loss when compared to those who were treated with medical therapy alone. Blood pressure changes were not significantly different among the two treatment groups. …

An Exploratory Study To Understand Factors Associated With Health-Related Quality Of Life Among Uninsured/Underinsured Patients As Identified By Clinic Providers And Staff, Guillermo M. Wippold, Nwakaego Nmezi, Jaime L. Williams, Jacqueline Butler, Tanya M. Hodge

Faculty Publications

Since the release of Healthy People 2020, there has been extensive research understanding factors associated with health-related quality of life (HRQoL) among specific populations. Despite this growing body of research, little has been conducted to understand the factors associated with HRQoL among uninsured/underinsured Americans. The purposes of the present study were to assess clinic staff to determine: (1) whether there is a need to examine HRQoL among uninsured/underinsured individuals, (2) whether there is a need for tailored HRQoL-promoting interventions among uninsured/underinsured individuals, and (3) the factors associated with HRQoL among uninsured/underinsured individuals. A survey was sent to an association of …

Needs Assessment: A Food Pharmacy During The Covid-19 Pandemic, Genesis Talavera

Master's Projects and Capstones

Introduction

The needs assessment report discusses the effects of COVID-19 (Coronavirus) pandemic on a low-income Hispanic/Latino population specifically for diabetic patients seeking food pharmacy services at a non-profit clinic in San Mateo County. Nutrition is an essential aspect of diabetes management, which can be challenging to obtain among low-income populations. The COVID-19 pandemic has caused additional challenges among the general population, making it more challenging for the diabetic low-income population. This project was undertaken to identify the effects COVID-19 has on the food pharmacy patients.

Methods

The needs assessment consisted of eleven in-depth interviews done in six week period. A …

Identifying And Structuring Long-Term Community Engagement Platforms For San Francisco's Ending The Hiv/Hcv/Sti Epidemics Initiative, Adam Landeros

Master's Projects and Capstones

Purpose: The primary objective for this project was to develop recommendations for a long-term community engagement structure and process for the ten-year implementation of the San Francisco Department of Public Health’s Ending the HIV/HCV/STI Epidemics initiative.

Background: Community engagement offers public health practitioners, researchers, and policymakers the opportunity for open, respectful dialogue with community members in pursuit of a common goal. This project was designed to explore different community engagement coordinators’ experiences with undertaking such initiatives, in order to inform a large-scale funding proposal being pursued by the San Francisco Department of Public Health (SFDPH).

Methods: Phase 1 of the …

Soil Quality Assessment In Rangelands Using A Minimum Data Set, Seyed Ata Rezaei, Susan S. Andrews

IGC Proceedings (1977-2023)

No abstract provided.

Establishment And Growth Of Legumes In Acid Soils In The Falkland Islands, Sergio Radic, James H. Mcadam

IGC Proceedings (1977-2023)

No abstract provided.

Fertilisation Strategies For Sown Organic Pasture In The Mediterranean Mountains Of Northeast Portugal, J. M. Pires, M. Rodrigues, M. Arrobas, J. Pires, N. Moreira

IGC Proceedings (1977-2023)

No abstract provided.

Enhancing Interactivity: How Has Design Exploration Of Physically And Intellectually Interactive Picturebooks Enhanced Shared Reading?, Nicholas Vanderschantz, Claire Timpany, Kristy Wright

DRS Biennial Conference Series

Children’s book design can have a significant impact on shared reading practices, interaction, and engagement. We hypothesise that books designed with the intention to specifically enhance the author’s story through interactivity will provide opportunities for new experience design outcomes that are both human-object and human-human centred. The multi-faceted problem of children’s books has been explored by linguistics, history, and education researchers, yet seldom using a design lens. In previous work we developed a traditional and highly interactive picturebook which we observe here being used by families. The study explored how physical and intellectual enhancements change the level and types of …

Method And System For Terpene Production Platforms In Yeast, Joseph Chappell, Xun Zhuang, Shuiqin Wu

Pharmaceutical Sciences Faculty Patents

A method is provided for producing modified mutant yeast and the resulting yeast that can be used as a platform for terpene production. The method includes chemical mutagenesis to effect ergosterol dependent growth in yeast. Subsequently, these yeast are subjected to an erg9 knockout mutation to thereby produce ergosterol dependent growth/ erg9 knockout mutation yeast cell lines. The resulting yeast are well suited for use in the production of terpenes.

A Pilot Study Used To Better Construct A Research Direction To Understand Where Industrial Design Fits Within The 4th Industrial Revolution (Industry 4.0), Christoph Heinrich Walter Koch, Blair Kuys, Gianni Renda

DRS Biennial Conference Series

The industrial design profession is engaging with a new manufacturing revolution — Industry4.0 (I4.0). This new paradigm presents new opportunities and challenges for industrial designers. However, it is still unclear what knowledge industrial designers can contribute to manufacturers in an emerging I4.0 context. This pilot study serves to determine the current state of practice of industrial design, and to discover areas of improvement as well as strengths to build on. Most importantly, this study functions as the first step to better qualify questions for a subsequent online questionnaire survey, in conjunction with findings from literature. A focus group was conducted …

Understanding Interactivity For The Strength-Training Needs Of The Elderly At Nursing Homes In Indonesia, Elizabeth Wianto, Chien-Hsu Chen, Irma Ruslina Defi, Erwani Merry Sartika, Aan Darmawan Hangkawidjaja, Yang-Cheng Lin

DRS Biennial Conference Series

Regular exercise has been shown to be beneficial for the elderly. However, the prevalence of the elderly doing exercise is low, and muscle-strengthening exercise is even lower. Therefore, physical inactivity has been reported as a significant health problem worldwide. Many assistive devices have been developed to overcome the problems of lack of engagement. This study explores opinions from the elderly regarding an acceptable and affordable technology-based design that focuses on the strength training specific to the elderly in two middle-class nursing homes in Indonesia. This paper presents qualitative findings from 37 participants who are part of an ongoing study. The …

Integral Living Research: Synergies In Research, Advocacy, And Healthy Living, Diana S. Nicholas, Yvonne Michael, Shivanthi Anandan

DRS Biennial Conference Series

The Integral Living Research (ILR) group approach derives from integral theory, appreciative evidence-based design, and social impact practices. This approach consists of a novel and collaborative design research method that melds the disciplines of architecture, interior design, public health, and STEM (Science, Technology, Engineering, and Math) fields into a synergistic whole that improves the capacity for change. Lack of housing equity in America has spurred this group to develop solutions to reduce housing-related stress and support enhanced well-being for urban families. The Integral Living Research (ILR) group deploys generative and empirical design research and has focused all efforts on the …

Multispecies Cohabitation And Future Design, Stanislav Roudavski

DRS Biennial Conference Series

How should humans live with animals and other forms of life? Could responses to this question improve the health and wellbeing of the biosphere? This paper argues that design researchers ought to engage nonhuman lifeforms as collaborators: informants and co-designers, or clients and users. Inspired by recent design challenges involving birds, bats and trees, this paper positions emancipatory multispecies cohabitation as a goal that can alleviate ongoing biodiversity losses and human-wildlife conflicts, in cities and beyond. It opens an interdisciplinary conversation by translating emerging scholarship in ethics, politics, and aesthetics to a narrative about desirable more-than-human cultures. This discussion has …

Protocol For A National Probability Survey Using Home Specimen Collection Methods To Assess Prevalence And Incidence Of Sars-Cov-2 Infection And Antibody Response, Aaron J. Siegler, Patrick S. Sullivan, Travis Sanchez, Ben Lopman, Mansour Fahimi, Charles Sailey, Martin Frankel, Richard Rothenberg, Colleen F. Kelley, Heather Bradley

Publications and Research

Purpose: The U.S. response to the SARS-CoV-2 epidemic has been hampered by early and ongoing delays in testing for infection; without data on where infections were occurring and the magnitude of the epidemic, early public health responses were not data-driven. Understanding the prevalence of SARSCoV- 2 infections and immune response is critical to developing and implementing effective public health responses. Most serological surveys have been limited to localities that opted to conduct them and/or were based on convenience samples. Moreover, results of antibody testing might be subject to high false positive rates in the setting of low prevalence of immune …

Heat Shock Protein 90 (Hsp90)-Inhibitor-Luminespib-Loaded-Protein-Based Nanoformulation For Cancer Therapy, Ankit K. Rochani, Sivakumar Balasubramanian, Aswathy Ravindran Girija, Toru Maekawa, Gagan Kaushal, Phd, D Sakthi Kumar

College of Pharmacy Faculty Papers

Drugs targeting heat shock protein 90 (Hsp90) have been extensively explored for their anticancer potential in advanced clinical trials. Nanoformulations have been an important drug delivery platform for the anticancer molecules like Hsp90 inhibitors. It has been reported that bovine serum albumin (BSA) nanoparticles (NPs) serve as carriers for anticancer drugs, which have been extensively explored for their therapeutic efficacy against cancers. Luminespib (also known as NVP-AUY922) is a new generation Hsp90 inhibitor that was introduced recently. It is one of the most studied Hsp90 inhibitors for a variety of cancers in Phase I and II clinical trials and is …

Spectral Light-Reflection Data Dimensionality Reduction For Timely Detection Of Yellow Rust, Ran Aharoni, Valentyna Klymiuk, Benny Sarusi, Sierra N. Young, Tzion Fahima, Barak Fishbain, Shai Kendler

Civil and Environmental Engineering Faculty Publications

Yellow rust (YR) wheat disease is one of the major threats to worldwide wheat production, and it often spreads rapidly to new and unexpected geographic locations. To cope with this threat, integrated pathogen management strategies combine disease-resistant plants, sensors monitoring technologies, and fungicides either preventively or curatively, which come with their associated monetary and environmental costs. This work presents a methodology for timely detection of YR that cuts down on hardware and computational requirements. It enables frequent detailed monitoring of the spread of YR, hence providing the opportunity to better target mitigation efforts which is critical for successful integrated disease …

Leveraging Empathic Strategies: Prototyping For Commercial Space Vehicle Design, Justin Lund, Jason O'Neill Germany

DRS Biennial Conference Series

When designers are tasked with the role of future forecaster, they engage in speculative acts that can be aided through prototyping. These tangible analogues act as a platform for building ideas as well as empathy in an effort to approximate the future activities and experiences of end users. The emergence of space tourism as a viable industry in the near future, will require designers to develop prototyping strategies that emulate these future experiences. To that end this paper reports on the development of a modular prototyping system for the design of space vehicle interiors. As a means of evaluating the …

Youth Participatory Research Evidence To Inform Health Policy: A Systematic Review Protocol, Janet Njelesani, Jean Hunleth

Open Access Publications

INTRODUCTION: Young people's participation in health research produces knowledge that is indispensable for creating appropriate and effective policies. However, how best to disseminate youth participatory research evidence to impact health policy is not known. Therefore, the objectives of this systematic review are to describe the evidence produced through youth participatory research, including the strategies used to disseminate youth participatory research evidence to health policymakers. These are necessary to improve policymakers' use of youth participatory research evidence and, thereby, make programmes more impactful for young people.

METHODS AND ANALYSIS: The meta-narrative methodology will guide the systematic review to highlight the contrasting …

The Dissemination And Implementation Of An Evidence-Based Eating Disorder Treatment: Online Training For Clinician Delivery Of Interpersonal Psychotherapy, Anna Karam

Arts & Sciences Graduate Student Theses and Dissertations

Introduction: Individuals with eating disorders often do not receive evidence-based care, such as interpersonal psychotherapy (IPT), partly due to lack of accessible clinician training in these treatments. In-person workshops are the standard method of therapist training; this method is expensive, time consuming, and requires an expert trainer. More scalable training and treatment fidelity assessment tools, such as online training and telephone-based simulation assessment of therapist treatment fidelity, are needed and could lead to greater dissemination of evidence-based treatment. The current study developed a novel IPT online training platform and telephone-based simulation assessment of therapist fidelity and examined: 1) whether online …

Seasonal Nutrition Content Changes Of Stockpiled And Standing Leymus Cinereus Forage, Barry L. Perryman, L. B. Bruce, K. Conley, L. Schmelzer, T. Wuligi

IGC Proceedings (1977-2023)

No abstract provided.

Use Of Biofertilizer In The Formation Of Joined Pastures With Brachiaria Decumbens And Stylosanthes Sp, L. M. Paiva, H. J. Fernandes, V. A. C. Dos Santos, F. P. De Oliveira, P. S. F. Trevisan, A. V. De Almeida

IGC Proceedings (1977-2023)

No abstract provided.

Growth And Development In Cultivars Of Phleum Pratense And Lolium Perenne During Winter, Liv Østrem, M. Jørgensen, M. Höglind

IGC Proceedings (1977-2023)

No abstract provided.

Effects Of Period And Temperature On Quality And Shelf-Life Of Cucumber And Garden-Eggs Packaged Using Cassava Starch-Zinc Nanocomposite Film, Adeshina Fadeyibi, Zinash Delebo Osunde, Mohammed Gana Yisa

Journal of Applied Packaging Research

Nanocomposite film can be used to prolong the shelf-life of fruits and vegetables. This research was undertaken to investigate the effects of packaging period and temperature on the quality and self-lives of cucumber and garden-eggs packaged using cassava starch-zinc nanocomposite film. Hundred grams each of cucumber and garden-eggs were wrapped in a 200× 350 mm size nanocomposite film and low density polyethylene (LDPE) of 2.240± 1.076 × 10^-10 gm^-1Pa^-1s^-1 water vapor and 1.568± 0.084× 10^-10 gm^-1Pa^-1s^-1 oxygen gas permeability. The products were stored at 10−27^oC temperatures …