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2020

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Leveraging Technology To Blend Large-Scale Epidemiologic Surveillance With Social And Behavioral Science Methods: Successes, Challenges, And Lessons Learned Implementing The Unite Longitudinal Cohort Study Of Hiv Risk Factors Among Sexual Minority Men In The United States, H. Jonathon Rendina, Ali J. Talan, Nicola F. Tavella, Jonathan Lopez Matos, Ruben H. Jimenez, S. Scott Jones, Brian Salfas, Drew Westmoreland Jan 2020

Leveraging Technology To Blend Large-Scale Epidemiologic Surveillance With Social And Behavioral Science Methods: Successes, Challenges, And Lessons Learned Implementing The Unite Longitudinal Cohort Study Of Hiv Risk Factors Among Sexual Minority Men In The United States, H. Jonathon Rendina, Ali J. Talan, Nicola F. Tavella, Jonathan Lopez Matos, Ruben H. Jimenez, S. Scott Jones, Brian Salfas, Drew Westmoreland

Publications and Research

The use of digital technologies to conduct large-scale research with limited interaction (i.e., no in-person contact) and objective endpoints (i.e., biological testing) has significant potential for the field of epidemiology, but limited research to date has been published on the successes and challenges of such approaches. We analyzed data from a cohort study of sexual minority men across the United States, collected using digital strategies during a 10-month period from 2017 to 2018. Overall, 113,874 individuals were screened, of whom 26,000 were invited to the study, 10,691 joined the study, and 7,957 completed all enrollment steps, including return of a …


And Still They Rise: Lessons From Students In New York City's Alternative Transfer High Schools, Mica Baum-Tuccillo, Varnica Arora, Alison Holstein, Michelle Fine Jan 2020

And Still They Rise: Lessons From Students In New York City's Alternative Transfer High Schools, Mica Baum-Tuccillo, Varnica Arora, Alison Holstein, Michelle Fine

Publications and Research

And Still They Rise is the first systematic analysis of alternative transfer schools in New York City – alternative educational spaces that keep their doors open to a range of students who seek an education despite past academic struggles. The report blends a qualitative and quantitative review of 842 students’ responses to a participatory survey that asked about goals, desires, obstacles, and what they found at transfer schools. In this report we present the stories and the statistics across schools, elevating silenced stories that lay behind the misnomer “at risk." We review data that shows how deeply students appreciate their …


Analysis Of Adult Neural Retina Extracellular Vesicle Release, Rna Transport And Proteomic Cargo, Jason Mighty, Jing Zhou, Alberto Benito-Martin, Sami Sauma, Samer Hanna, Onyekwere Onwumere, Cui Shi, Martin Muntzel, Moira Sauane, Michael Young, Henrik Molina, Dianne Cox, Stephen Redenti Jan 2020

Analysis Of Adult Neural Retina Extracellular Vesicle Release, Rna Transport And Proteomic Cargo, Jason Mighty, Jing Zhou, Alberto Benito-Martin, Sami Sauma, Samer Hanna, Onyekwere Onwumere, Cui Shi, Martin Muntzel, Moira Sauane, Michael Young, Henrik Molina, Dianne Cox, Stephen Redenti

Publications and Research

PURPOSE. Extracellular vesicles (EVs) contain RNA and protein cargo reflective of the genotype and phenotype of the releasing cell of origin. Adult neural retina EV release, RNA transfer, and proteomic cargo are the focus of this study.

METHODS. Adult wild-type mouse retinae were cultured and released EV diameters and concentrations quantified using Nanosight. Immunogold transmission electron microscopy (TEM) was used to image EV ultrastructure and marker protein localization. Quantitative real-time polymerase chain reaction (qRT-PCR) was used to analyze retinal cell transcripts present in EVs. Super-resolution microscopy was used to image fluorescent (green) RNA and (red) lipid membrane labeled EVs, released …


The Role Of Warm, Dry Summers And Variation In Snowpack On Phytoplankton Dynamics In Mountain Lakes, Isabella A. Olesky, Whitney S. Beck, Roderick W. Lammers, Cara E. Steger, Codie Wilson, Kyle R. Christianson, Kim Vincent, Gunnar Forrest Johnson, Pieter T.J. Johnson, Jill S. Baron Jan 2020

The Role Of Warm, Dry Summers And Variation In Snowpack On Phytoplankton Dynamics In Mountain Lakes, Isabella A. Olesky, Whitney S. Beck, Roderick W. Lammers, Cara E. Steger, Codie Wilson, Kyle R. Christianson, Kim Vincent, Gunnar Forrest Johnson, Pieter T.J. Johnson, Jill S. Baron

Geology Faculty Publications and Presentations

Climate change is altering biogeochemical, metabolic, and ecological functions in lakes across the globe. Historically, mountain lakes in temperate regions have been unproductive because of brief ice-free seasons, a snowmelt-driven hydrograph, cold temperatures, and steep topography with low vegetation and soil cover. We tested the relative importance of winter and summer weather, watershed characteristics, and water chemistry as drivers of phytoplankton dynamics. Using boosted regression tree models for 28 mountain lakes in Colorado, we examined regional, intraseasonal, and interannual drivers of variability in chlorophyll a as a proxy for lake phytoplankton. Phytoplankton biomass was inversely related to the maximum snow …


Risk Perception, Bias, And Resistance To New Food Tech: The Case Of Gmos, Michael David Wanlass Jan 2020

Risk Perception, Bias, And Resistance To New Food Tech: The Case Of Gmos, Michael David Wanlass

Agribusiness and Applied Economics

GMOs are very controversial among consumers. Many fear that they may have risks scientists are not accounting for. Some GMOs, such as GMO soybean oil, have concerns over their processing methods as well. Traditional risk assessments that only account for hazard do not take these fears into account. Including risk perception, bias, and resistance is a way to account for consumers’ fears. Risk perception, bias, and resistance together create an aggregate that in turn affects willingness-to-purchase. A discrete choice experiment assessed risk perception of, bias towards, and resistance towards GMOs. Respondents revealed their preferences between buying GMO or non-GMO soybean …


Towards An Ecocentric Movement?, David Johns Jan 2020

Towards An Ecocentric Movement?, David Johns

Political Science Faculty Publications and Presentations

An ecocentric movement is one which mobilizes and organizes people to transform, or abolish and replace, existing anthropocentric societies, which seek to dominate the other-than-human world. The instrumentalities of anthropocentric domination will not simply wither away. They must be forcefully dismantled. That dismantling will be neither quick nor easy, and will be met with enormous resistance from those that benefit from domination, and from those that fear change. Only by keeping one’s eyes on the prize – the recovery of biodiversity and the Earth – and not being diverted by other goals, can the prize be attained.


The Pacific Sentinel, January 2020, Portland State University. Student Publications Board Jan 2020

The Pacific Sentinel, January 2020, Portland State University. Student Publications Board

The Pacific Sentinel

Editor: Jake Johnson

Articles in this issue include:

  • Letter from the Editor
  • Study Determines How Measles Destroys the Immune System
  • Another Police Shooting: A Whose Fault WHODUNNIT?
  • (News) Portlanders Join Nationwide Rallies to Impeach and Remove Trump
  • (Opinion) Reconstructing America
  • The Uyghurs: A Fading Chapter
  • Chickens Are for Hugging
  • The Myth of Vegan Virtuosity
  • Stop Saying "Be Grateful for What You Have"
  • Who Would Make a Baking Challenge Like That?! Zumbo Would.
  • Best of 2019 Staff Picks
  • Baby Ketten Finds Its Forever Home
  • (Satire) How to Deal With the Crushing Weight of Familial Rejection Next Holiday Season


Pathos, Winter 2020, Portland State University. Student Publications Board Jan 2020

Pathos, Winter 2020, Portland State University. Student Publications Board

Pathos

Editor: Sadie Jordan


Family Features Of Social Withdrawal Syndrome (Hikikomori), Malagón-Amor, Luis Miguel Martín-López, David Corcoles, Anna González, Magda Bellsolà, Alan R. Teo, Antoni Bulbena, Victor Pérez, Daniel Bergé Jan 2020

Family Features Of Social Withdrawal Syndrome (Hikikomori), Malagón-Amor, Luis Miguel Martín-López, David Corcoles, Anna González, Magda Bellsolà, Alan R. Teo, Antoni Bulbena, Victor Pérez, Daniel Bergé

Psychology Faculty Publications and Presentations

Background: Family may play an important role in the origin, maintenance, and treatment of people with social withdrawal. The aim of this study is to analyze family factors related to social withdrawal syndrome.

Methods: Socio-demographic, clinical, and family data, including family psychiatric history, dysfunctional family dynamics, and history of family abuse were analyzed in 190 cases of social withdrawal with a minimum duration of 6 months that started an at-home treatment program. Data were analyzed at baseline and at 12 months.

Results: In 36 cases (18%) neither the patient nor the family allowed at home evaluation and treatment by the …


Teaching An International Bestseller: Reflections On Encouraging Caring Global Citizenship, Evguenia Davidova Jan 2020

Teaching An International Bestseller: Reflections On Encouraging Caring Global Citizenship, Evguenia Davidova

International & Global Studies Faculty Publications and Presentations

This article discusses an integrative model of gradual scaffolding of curricular and pedagogical strategies, based on the theoretical framework of a “caring global citizenship.” It provides concrete practices for internationalization of general education that could be implemented in a wide variety of institutional settings. Such a model addresses ethnocentrism by expanding students' knowledge and perspectives on societies influenced by American politics, and fosters empathy as both value and skill.


Shah Rukh Khan: Journey From Charisma To Celebrity, Priya Kapoor Jan 2020

Shah Rukh Khan: Journey From Charisma To Celebrity, Priya Kapoor

International & Global Studies Faculty Publications and Presentations

Chapter 3. This essay studies the particular brand of Shah Rukh Khan (SRK) as he achieves superstardom in the Hindi film industry and as a thought leader, earn ing him the moniker Badshah (king). By transcending ossifying gender roles and ethnic-religious divisions might SRK be the quintessential Indian man who stands for the nation (Cayla in Advertising Soc Rev 9(2), 2008)? Or is he a modern metro sexual whose identity is hybrid? This accounts for the dialectical tension that arises from the ‘celebrity’ of SRK as global businesses boldly recruit cinephile audiences as consumer-patriots of neoliberal India transforming dated identities …


The Importance Of “Being There”: A Qualitative Study Of What Veterans With Depression Want In Social Support, Alan R. Teo, Heather E. Marsh, S. Ono, Christina Nicolaidis, Somnath Saha, Steven K. Dobscha Jan 2020

The Importance Of “Being There”: A Qualitative Study Of What Veterans With Depression Want In Social Support, Alan R. Teo, Heather E. Marsh, S. Ono, Christina Nicolaidis, Somnath Saha, Steven K. Dobscha

School of Social Work Faculty Publications and Presentations

Background: Social connectedness exerts strong influences on health, including major depression and suicide. A major component of social connectedness is having individual relationships with close supports, romantic partners and other trusted members of one’s social network. Objective: The objective of this study was to understand how individuals’ relationships with close supports might be leveraged to improve outcomes for primary care patients with depression and at risk for suicide. Design: In this qualitative study, a semi-structured interview guide was used to probe patient experiences, views, and preferences related to social support. Participants: We conducted interviews with 30 primary care patients at …


Parent Health Beliefs, Social Determinants Of Health, And Child Health Services Utilization Among Us School-Age Children With Autism, Katharine Zuckerman, Olivia J. Lindly, Brianna Sinche, Christina Nicolaidis Jan 2020

Parent Health Beliefs, Social Determinants Of Health, And Child Health Services Utilization Among Us School-Age Children With Autism, Katharine Zuckerman, Olivia J. Lindly, Brianna Sinche, Christina Nicolaidis

School of Social Work Faculty Publications and Presentations

Objective—Substantial variation exists in ASD care by race, ethnicity, and socioeconomic status; however, the role of parent health beliefs in this variation is poorly understood. Study goals were to (1) examine variation in parent beliefs about ASD prognosis and treatment according to social determinants of health (SDH) and (2) assess whether this variation was associated with variable health services utilization, among 1420 children with special health care needs (CSHCN) having autism spectrum disorder (ASD). Methods—We used linked data from the 2011 Survey of Pathways to Diagnosis and Treatment and the 2009/10 National Survey of Children with Special Health Care Needs. …


Albina Zone, Lisa K. Bates Jan 2020

Albina Zone, Lisa K. Bates

Urban Studies and Planning Faculty Publications and Presentations

Story Summary:
In near future Portland, the police have been abolished, but what else is needed for real liberation? A gifted young woman and her mother struggle to communicate across a rift of unspoken history.

Foreword to Black Freedom Beyond Borders: Memories of Abolition Day

There are times when our lived reality feels stranger than science fiction - a viral pandemic, an economic crisis, global conflicts on multiple frontlines, the rise of white supremacist racism, a wave of state violence against Black bodies, the fiery uprisings across the nation, and militarized guards deployed in response… It was the Red Summer …


The Next Step: A Guide To Framing And Designing Permanent Supportive Housing For Caritas Housing, Julianne Reno, Ryan Dyar, N. Janine Gates, Joshua Ollinger, Hugo Hamblin-Agosto Jan 2020

The Next Step: A Guide To Framing And Designing Permanent Supportive Housing For Caritas Housing, Julianne Reno, Ryan Dyar, N. Janine Gates, Joshua Ollinger, Hugo Hamblin-Agosto

Master of Urban and Regional Planning Workshop Projects

Caritas Housing of Oregon develops affordable housing for persons experiencing homelessness across the state. In January 2020, staff reached out to students in the Master of Urban and Regional Planning Program seeking planning assistance. Caritas wanted help planning for the needs of future residents and navigating what is frequently an emotionally-fraught and politically-charged development process. Upstream Planning worked with Caritas Housing to create resident-informed development criteria and design a framework for public communication. The Upstream Planning team created two documents, Development Criteria Guide and Public Communication Guide, that work towards the singular goal of helping Caritas develop permanent supportive housing …


Subito 2020, Portland State University. School Of Music & Theater Jan 2020

Subito 2020, Portland State University. School Of Music & Theater

Subito: Student Voices from Portland State University School of Music & Theater

Issue 3, Spring 2020

Warsaw Autumns: The New Polish School. John Coltrane's transformation. Darrell Grant on finding, connecting with, and serving your community. Reviews of Jesse McCann's Classical Guitar Pedagogy, and the L.A. Philharmonic's Sustain. Damien Geter's An African American Requiem

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An Expert Discussion On Structural Racism In Autism Research And Practice, Desiree R. Jones, Christina Nicolaidis, Lisa J. Ellwood, Arianne Garcia, Khalilah R. Johnson, Kristina Lopez, T. C. Waisman Jan 2020

An Expert Discussion On Structural Racism In Autism Research And Practice, Desiree R. Jones, Christina Nicolaidis, Lisa J. Ellwood, Arianne Garcia, Khalilah R. Johnson, Kristina Lopez, T. C. Waisman

School of Social Work Faculty Publications and Presentations

Autism research has a race problem. Despite improvements in screening and diagnosis, autism continues to be underdiagnosed in Black and Hispanic children , and those who obtain a diagnosis often have limited access to support services. Racial disparities persist during the transition to adulthood, with autistic adults from racial and ethnic minority groups experiencing a number of challenges, including lower rates of employment, social participation, and postsecondary education compared to White autistic adults. While these studies highlight the important intersection between race, ethnicity and autism, people of color remain consistently under-represented in autism research , and dialogues regarding the impact …


Syrian Refugees’ Perspectives And Service Providers’ Viewpoints On Major Needs And Future Plans In Jordan, Mitra Naseh, Natalia Liviero, Maryam Rafieifar, Zahra Abtahi, Miriam Potocky Jan 2020

Syrian Refugees’ Perspectives And Service Providers’ Viewpoints On Major Needs And Future Plans In Jordan, Mitra Naseh, Natalia Liviero, Maryam Rafieifar, Zahra Abtahi, Miriam Potocky

School of Social Work Faculty Publications and Presentations

The ongoing civil war in Syria created the world’s largest refugee crisis since World War II. As exile continues for many Syrians, this study aimed to explore what refugees perceive as their major needs and plans for the future in comparison to what service providers believe is needed and should be planned in Jordan. Phenomenological design and inductive reasoning were used in this study to explore refugees’ needs and future plans from the etic view by interviewing key informants and from the emic view by analyzing interviews with refugees. After coding and comparing the key informants’ interviews and refugees’ narratives, …


Easa Connections: Community-Based Participatory Research To Develop A Peer-Based Early Psychosis Web Resource With Young Adults, Dora Raymaker, Tamara G. Sale, Mariam Rija, Nicholas Buekea, Nybelle Caruso, Ryan P. Melton, Natalie Cohrs, Veronica Gould, Christina Wall, Mirah L. Scharer Jan 2020

Easa Connections: Community-Based Participatory Research To Develop A Peer-Based Early Psychosis Web Resource With Young Adults, Dora Raymaker, Tamara G. Sale, Mariam Rija, Nicholas Buekea, Nybelle Caruso, Ryan P. Melton, Natalie Cohrs, Veronica Gould, Christina Wall, Mirah L. Scharer

School of Social Work Faculty Publications and Presentations

Young adults (YA) who have experienced early psychosis (EP) have valuable information about their recovery process yet are often left out of research. We used a community-based participatory research (CBPR) approach in partnership with the Early Assessment and Support Alliance (EASA) EP program and Portland State University to develop a peer-driven, web-based, recovery resource.We used our CBPR process to collaboratively develop the resource and conducted an iterative usability study to test and refine it. The resource was well-received and accessible. YA partners emphasize the importance of being prepared to learn about research and one’s self, being open to new experiences, …


Conceptual Paper For Re-Validating The Teacher Of Deafblind And Intervener Competencies, Susan Bruce, Cathy Nelson, Amy T. Parker, Debbie Sanders, Adam Graves, Carol Rimka Jan 2020

Conceptual Paper For Re-Validating The Teacher Of Deafblind And Intervener Competencies, Susan Bruce, Cathy Nelson, Amy T. Parker, Debbie Sanders, Adam Graves, Carol Rimka

Special Education Faculty Publications and Presentations

An overview of the standards for the role of Teacher of the Deafblind (TBD) and the paraprofessional Intervener.


Review Of The Book: Silenced In The Library: Banned Books In America, By Zeke Jarvis, Rhiannon M. Cates Jan 2020

Review Of The Book: Silenced In The Library: Banned Books In America, By Zeke Jarvis, Rhiannon M. Cates

Library Faculty and Staff Publications and Presentations

This is a book review of the book Silenced in the Library: Banned Books in America, by Zeke Jarvis.


Rapid Deployment Of A Statewide Covid-19 Echo Program For Frontline Clinicians: Early Results And Lessons Learned, Anna Louise Steeves-Reece, Nancy Elder, Tuesday A. Graham, Miriam L. Wolf, Isabel Stock, Melinda M. Davis, Robert D. Stock Jan 2020

Rapid Deployment Of A Statewide Covid-19 Echo Program For Frontline Clinicians: Early Results And Lessons Learned, Anna Louise Steeves-Reece, Nancy Elder, Tuesday A. Graham, Miriam L. Wolf, Isabel Stock, Melinda M. Davis, Robert D. Stock

OHSU-PSU School of Public Health Faculty Publications and Presentations

In a pattern repeated around the country, Oregon reported its first coronavirus patient on February 28, 2020.1 A week later, the governor declared a state of emergency.2 While the media initially focused on efforts to address COVID-19 in large cities, many rural communities were working in parallel to prepare. In these rural areas, there was an increasing concern that the burden of COVID-19 may be particularly dire due to factors such as older populations, higher prevalence of chronic diseases and poverty, and less health care access.3-6 Rural clinicians, especially those working in outpatient settings, are caring for patients during the …


Using Facebook For Qualitative Research: A Brief Primer, Daschel Franz, Heather Elizabeth Marsh, Jason Chen, Alan R. Teo Jan 2020

Using Facebook For Qualitative Research: A Brief Primer, Daschel Franz, Heather Elizabeth Marsh, Jason Chen, Alan R. Teo

OHSU-PSU School of Public Health Faculty Publications and Presentations

As Facebook continues to grow its number of active users, the potential to harness data generated by Facebook users also grows. As much of Facebook users’ activity consists of creating (and commenting on) written posts, the potential use of text data for research is enormous. However, conducting a content analysis of text from Facebook users requires adaptation of research methods used for more traditional sources of qualitative data. Furthermore, best practice guidelines to assist researchers interested in conducting qualitative studies using data derived from Facebook are lacking. The purpose of this primer was to identify opportunities, as well as potential …


Strong Men, Strong Communities: Design Of A Randomized Controlled Trial Of A Diabetes Prevention Intervention For American Indian And Alaska Native Men, Ka‘Imi Sinclair, Cara Carty, Kelly L. Gonzales, Cassandra Nikolaus, Lucas Gillespie, Dedra Buchwald Jan 2020

Strong Men, Strong Communities: Design Of A Randomized Controlled Trial Of A Diabetes Prevention Intervention For American Indian And Alaska Native Men, Ka‘Imi Sinclair, Cara Carty, Kelly L. Gonzales, Cassandra Nikolaus, Lucas Gillespie, Dedra Buchwald

OHSU-PSU School of Public Health Faculty Publications and Presentations

Type 2 diabetes is a serious global epidemic that disproportionately affects disadvantaged populations. American Indians and Alaska Natives (AIs/ANs) have the highest rates of diabetes in the nation with a prevalence of 14.7% in 2018, more than twice that of non-Hispanic Whites. AI/AN men have the highest prevalence of diagnosed type 2 diabetes (14.5%) compared to non-Hispanic Black (11.4%), non-Hispanic Asian (10.0%), and non-Hispanic White (8.6%) men. Several landmark clinical trials have shown that lifestyle interventions can effectively prevent or delay the onset of diabetes among those at risk, including in AIs/ANs. Despite positive outcomes for AIs/ANs in these studies, …


There’S More To The Story: Both Individual And Collective Policy Narratives Can Increase Support For Community-Level Action, Chris Skurka, Jeff Niederdeppe, Liana Winett Jan 2020

There’S More To The Story: Both Individual And Collective Policy Narratives Can Increase Support For Community-Level Action, Chris Skurka, Jeff Niederdeppe, Liana Winett

OHSU-PSU School of Public Health Faculty Publications and Presentations

Narratives can convey the need or community-level action to address social problems. Yet narratives often tell stories about specific individuals rather than the broader collectives these problems affect. Some theorists argue that individualizing collective problems inhibits audiences from recognizing upstream causes and solutions. This study tested how narrative individualization (whether a story focuses on an individual case or a larger collective) might produce trade-offs when mobilizing support for community-level policies to address childhood obesity. We also investigated whether narratives using language congruent with political partisans’ morals (equity or loyalty) might minimize polarized responses to such narratives. A large, Web-based experiment …


Off-Label Drug Risks: Toward A New Fda Regulatory Approach, George Horvath Jan 2020

Off-Label Drug Risks: Toward A New Fda Regulatory Approach, George Horvath

Faculty Scholarship

No abstract provided.


Sentenced To Surveillance: Fourth Amendment Limits On Electronic Monitoring, Kate Weisburd Jan 2020

Sentenced To Surveillance: Fourth Amendment Limits On Electronic Monitoring, Kate Weisburd

Faculty Scholarship

As courts and legislatures increasingly recognize that “digital is different” and attempt to limit government surveillance of private data, one group is conspicuously excluded from this new privacy-protective discourse: the five million people in the United States on probation, parole, or other forms of community supervision. This Article is the first to explore how warrantless electronic surveillance is dramatically transforming community supervision and, as a result, amplifying a growing privacy-protection disparity: those in the criminal legal system are increasingly losing privacy protections even while those not in the system are increasingly gaining privacy protections. The quickly expanding use of GPS-equipped …


The Legal Reconstruction Of Walls: N.D. & N.T. V. Spain, 2017, 2020, Moria Paz Jan 2020

The Legal Reconstruction Of Walls: N.D. & N.T. V. Spain, 2017, 2020, Moria Paz

Faculty Scholarship

Recently, Western democracies have turned to building border walls as a strategy of immigration control. This Article makes two claims. First, human rights courts and quasi-judicial bodies are deeply implicated in this move. In the past decade or so, these institutions have been successful in both enforcing and creating new rights for asylum seekers and irregular migrants. They have used variants of access to guarantee hyper-protection to individual non-nationals who have either entered a host state or come under its effective control. This legal success has resulted in the unintended consequence of rendering wall-building a logical move for state prevention …


Enhancing Final Image Contrast In Off-Axis Digital Holography Using Residual Fringes, Manuel Bedrossian, Kent Wallace, Eugene Serabyn, Chris Lindensmith, Jay Nadeau Jan 2020

Enhancing Final Image Contrast In Off-Axis Digital Holography Using Residual Fringes, Manuel Bedrossian, Kent Wallace, Eugene Serabyn, Chris Lindensmith, Jay Nadeau

Physics Faculty Publications and Presentations

We show that background fringe-pattern subtraction is a useful technique for removing static noise from off-axis holographic reconstructions and can enhance image contrast in volumetric reconstructions by an order of magnitude in the case for instruments with relatively stable fringes. We demonstrate the fundamental principle of this technique and introduce some practical considerations that must be made when implementing this scheme, such as quantifying fringe stability. This work also shows an experimental verification of the background fringe subtraction scheme using various biological samples.


Characterization Of Retinol Stabilized In Phosphatidylcholine Vesicles With And Without Antioxidants, Yekaterina G. Chmykh, Jay Nadeau Jan 2020

Characterization Of Retinol Stabilized In Phosphatidylcholine Vesicles With And Without Antioxidants, Yekaterina G. Chmykh, Jay Nadeau

Physics Faculty Publications and Presentations

Retinol stability has been reported to be improved by encapsulation in liposomes, both with and without cholesterol. However, this improvement is limited because of lipid peroxidation. In this study, we compare the stability of retinol in phosphatidylcholine liposomes under ultraviolet (UV) light or standard room air, with and without the addition of antioxidants. Both butylated hydroxytoluene (BHT) and a proprietary mix (StoppOx) improved the shelf stability from vesicles, including within the aqueous layer. Fluorescence lifetimes were equally heterogeneous. Under UV irradiation, StoppOx protected retinol for significantly longer than BHT and via different mechanisms. This suggests that natural antioxidants work well …