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Articles 74041 - 74070 of 74688
Full-Text Articles in Entire DC Network
Learning Strategies And Metacognition In Adults With Dyslexia, Bradley W. Bergey
Learning Strategies And Metacognition In Adults With Dyslexia, Bradley W. Bergey
Publications and Research
In this chapter, we review the literature on learning and study strategies of university students with reading disabilities. Increasing numbers of students with reading disabilities attend post-secondary education, and while there, many experience academic challenges related to their remaining reading problems. We propose that learning and study strategies are important compensatory mechanisms for these students, but conclude not much is currently known about the learning and study strategies that students with reading disabilities employ in post-secondary education. As a way forward, we identify measurement and sampling issues in existing studies as potentially responsible for the varied results and discuss the …
An Exploration Of Pharmacy Education Researchers' Perceptions And Experiences Conducting Qualitative Research, Antonio A. Bush, Mauriell Amechi, Adam Persky
An Exploration Of Pharmacy Education Researchers' Perceptions And Experiences Conducting Qualitative Research, Antonio A. Bush, Mauriell Amechi, Adam Persky
Educational Leadership & Workforce Development Faculty Publications
Objective. To investigate pharmacy education researchers' experiences in conducting qualitative research and their perceptions of qualitative research in pharmacy education
Methods. A phenomenological approach was used to conduct one-time, in-depth interviews with 19 participants from 12 schools and colleges of pharmacy. Interview transcripts were coded and themes were identified using a modified form of the Sort and Sift, Think and Shift method of data analysis.
Results. Faculty members were the largest subgroup in the sample, followed by graduate students, postdoctoral fellows/scholars, and residents. Pharmacy education researchers had varying levels of training in conducting qualitative research and some had none at …
Qualitative Research In Pharmacy Education: An Exploration Of Pharmacy Education Researchers' Perceptions And Experiences Conducting Qualitative Research, Antonio A. Bush, Mauriell Amechi, Adam Persky
Qualitative Research In Pharmacy Education: An Exploration Of Pharmacy Education Researchers' Perceptions And Experiences Conducting Qualitative Research, Antonio A. Bush, Mauriell Amechi, Adam Persky
Educational Leadership & Workforce Development Faculty Publications
Objective. To investigate pharmacy education researchers’ experiences in conducting qualitative research and their perceptions of qualitative research in pharmacy education
Methods. A phenomenological approach was used to conduct one-time, in-depth interviews with 19 participants from 12 schools and colleges of pharmacy. Interview transcripts were coded and themes were identified using a modified form of the Sort and Sift, Think and Shift method of data analysis.
Results. Faculty members were the largest subgroup in the sample, followed by graduate students, postdoctoral fellows/scholars, and residents. Pharmacy education researchers had varying levels of training in conducting qualitative research and some had none at …
Pathways To Success In Anatomy And Physiology At The Community College: The Role Of Prerequisite Courses, Staci B. Forgey, Mitchell R. Williams, Shana Pribesh
Pathways To Success In Anatomy And Physiology At The Community College: The Role Of Prerequisite Courses, Staci B. Forgey, Mitchell R. Williams, Shana Pribesh
Educational Leadership & Workforce Development Faculty Publications
Gatekeeper courses such as Anatomy and Physiology are often referenced in discussions regarding the national shortage of persons in allied health professions. In an attempt to bolster access to STEM professions, some community colleges are mandating prerequisite courses such as Natural Sciences and/or General Biology for STEM gatekeeping courses. In this study, we examined which of these prerequisite courses helped students to pass Anatomy and Physiology and whether the courses are an additional barrier to STEM field completion. This was the first study to evaluate whether a prerequisite course was predictive of success in Anatomy and Physiology, and it contributes …
Reconceptualizing College Impact Studies Through A Fractal Assemblage Theory, Laura Elizabeth Smithers
Reconceptualizing College Impact Studies Through A Fractal Assemblage Theory, Laura Elizabeth Smithers
Educational Leadership & Workforce Development Faculty Publications
College impact studies have formed the common sense of understanding institutional relationships to student growth and change for decades. In this time, they have become entangled with the production of the neoliberal university. This paper1 presents an alternative theorization of student change on campus, a fractal assemblage theory. Assemblage theory is discussed through a single common language of major assemblage theory concepts across four authors. After exploring these concepts in depth, this paper returns to the stakes of assemblage theory: higher education research not to channel student to predetermined outcomes, but to create student futures in excess of our …
Was It Worth It? Using Student Loans To Finance A College Degree, William L. Nuckols, Kim E. Bullington, Dennis E. Gregory
Was It Worth It? Using Student Loans To Finance A College Degree, William L. Nuckols, Kim E. Bullington, Dennis E. Gregory
Educational Leadership & Workforce Development Faculty Publications
This qualitative study explores the perceptions of value added to the lives of graduates who borrowed money to fund their college educations. Through the lens of cognitive dissonance theory, five themes emerged. Overall, the study participants agreed that the ability to take on student loans to fund their education was worth it, but on the other hand feel overburdened with the cost of paying back their loans. This paper also provides a foundation for future research and identifies public policy shortcomings and suggests solutions.
Are (We) Going Deep Enough?: A Narrative Literature Review Addressing Critical Race Theory, Radical Space Theory, And Black Identity Development, Kala Burrell-Craft
Are (We) Going Deep Enough?: A Narrative Literature Review Addressing Critical Race Theory, Radical Space Theory, And Black Identity Development, Kala Burrell-Craft
Educational Leadership & Workforce Development Faculty Publications
A narrative literature review was conducted to examine how researchers address the concept of intersectionality using critical race theory, racial space theory, and Black identity development. A Boolean search revealed 18 articles met criteria for consideration. Multiple reviews occurred to isolate the articles that contained all the search criteria and multiple reviews occurred that selected the Boolean phrase or phrases that the researcher was searching for. Thirteen of the 18 articles met one or more search criteria and were included in the review, however, no articles matched 100 percent for inclusion. Thus, indicating we are not going deep enough in …
"We Dare Say Love": Supporting Achievement In The Educational Life Of Black Boys (Book Review), Kala Burrell-Craft
"We Dare Say Love": Supporting Achievement In The Educational Life Of Black Boys (Book Review), Kala Burrell-Craft
Educational Leadership & Workforce Development Faculty Publications
No abstract provided.
Family Structure Stability And Transitions, Parental Involvement, And Educational Outcomes, Shana L. Pribesh, Jane Smith Carson, Mikaela J. Dufur, Yuanyuan Yue, Kathy Morgan
Family Structure Stability And Transitions, Parental Involvement, And Educational Outcomes, Shana L. Pribesh, Jane Smith Carson, Mikaela J. Dufur, Yuanyuan Yue, Kathy Morgan
Educational Leadership & Workforce Development Faculty Publications
The family environments children live in have profound effects on the skills, resources, and attitudes those children bring to school. Researchers studying family structure have found that children who live with two married, opposite-sex, biological parents, on average, have better educational outcomes than children living in alternate family structures, perhaps due to higher resources, lower stressors, or different selectivity patterns. Socioeconomic stratification plays a major role in family structure, with low-income families seeing more instability. We argue that the impact of family structure is attenuated by transitions in and out of family structures that may decrease a specific resource important …
Teacher Support Of Co- And Socially-Shared Regulation Of Learning In Middle School Mathematics Classrooms, Melissa Quackenbush, Linda Bol
Teacher Support Of Co- And Socially-Shared Regulation Of Learning In Middle School Mathematics Classrooms, Melissa Quackenbush, Linda Bol
Educational Leadership & Workforce Development Faculty Publications
Social influences on classroom learning have a long research tradition and are critical components of self-regulated learning theories. More recently, researchers have explored the social influences of self-regulated learning in cooperative learning contexts. In these settings, co-regulation of learning and socially-shared regulation of learning strategies have been aligned with self-regulated learning theory. However, without specific training or structure, teachers are not likely to explicitly integrate SRL strategies into their teaching. We use case studies to better understand how Zimmerman's theory of self-regulated learning (2008) and Hadwin's conceptual framework of socially-shared regulation of learning (2018) emerge from teachers' support of student-centered …
Online Adaptive Learning: A Study Of Score Validity Of The Adaptive Self-Regulated Learning Model, Hoda Harati, Cherng-Jyh Yen, Chih-Hsiung Tu, Brandon J. Cruickshank, Shadow William Jon Armfield
Online Adaptive Learning: A Study Of Score Validity Of The Adaptive Self-Regulated Learning Model, Hoda Harati, Cherng-Jyh Yen, Chih-Hsiung Tu, Brandon J. Cruickshank, Shadow William Jon Armfield
Educational Leadership & Workforce Development Faculty Publications
Adaptive Learning (AL), a new web-based online learning environment, requires self-regulated learners who act autonomously. However, to date, there appears to be no existing model to conceptualize different aspects of SRL skills in Adaptive Learning Environments (ALE). The purpose of this study was to design and empirically evaluate a theoretical model of Self-Regulated Learning (SRL) in ALE's and the related questionnaire as a measurement tool. The proposed theoretical model, namely, “Adaptive Self-Regulated Learning (ASR)”, was specified to incorporate the SRL skills into ALE's. Based on this model, the Adaptive Self-regulated Learning Questionnaire (ASRQ) was developed. The reliability and validity of …
Developing Engaged Scholars Through Glocal Learning: A Case Study Of The Thailand Global Citizenship And Civic Engagement Initiative, Sornnate Areesophonpichet, Chris R. Glass, Rachawan Wongtrirat
Developing Engaged Scholars Through Glocal Learning: A Case Study Of The Thailand Global Citizenship And Civic Engagement Initiative, Sornnate Areesophonpichet, Chris R. Glass, Rachawan Wongtrirat
Educational Leadership & Workforce Development Faculty Publications
With the development of Thailand 4.0, it is critical for engaged scholars to address the role of higher education in Thailand’s social and economic development with an understanding of how local histories (local) and economic globalization (global) shape their work. We discuss the Thai context for community engagement, then describe the purpose and learning goals for the Global Citizenship and Civic Engagement (GCCE) initiative, as well as the methodological approach used to assess the initiative’s impact and long-term sustainability. The findings highlight how glocal learning fostered Thai and U.S. graduate students’ valuing local knowledge and linking economic inequality to environmental …
Mode Discrimination In Dissipatively Coupled Laser Arrays, Jiajie Ding, Mohammad-Ali Miri
Mode Discrimination In Dissipatively Coupled Laser Arrays, Jiajie Ding, Mohammad-Ali Miri
Publications and Research
No abstract provided.
Where Everybody Knows Your Name, Emily Stier Adler
Where Everybody Knows Your Name, Emily Stier Adler
Sociology Between the Gaps: Forgotten and Neglected Topics
No abstract provided.
The Gender Gap In Political Affiliation: Understanding Why It Emerged And Maintained Itself Over Time, Lindsay Petit, Madison Mellor, Roger Clark
The Gender Gap In Political Affiliation: Understanding Why It Emerged And Maintained Itself Over Time, Lindsay Petit, Madison Mellor, Roger Clark
Sociology Between the Gaps: Forgotten and Neglected Topics
No abstract provided.
Creative Destruction And Cultural Lag In The Digital Age, George Ritzer, Piergiorgio Degli Esposti
Creative Destruction And Cultural Lag In The Digital Age, George Ritzer, Piergiorgio Degli Esposti
Sociology Between the Gaps: Forgotten and Neglected Topics
No abstract provided.
Retrospection
Sociology Between the Gaps: Forgotten and Neglected Topics
No abstract provided.
Sociology Between The Gaps Volume 5 (2020)
Sociology Between The Gaps Volume 5 (2020)
Sociology Between the Gaps: Forgotten and Neglected Topics
No abstract provided.
Clinical Nurses' Perspectives On Discharge Practice Changes From Participating In A Translational Research Study, Kathleen L. Bobay, Regina Conway-Philips, Ronda G. Hughes, Linda L. Costa, Sarah J. Bahr, Danielle M. Siclovan, Susan A. Nuccio, Marianne E. Weiss
Clinical Nurses' Perspectives On Discharge Practice Changes From Participating In A Translational Research Study, Kathleen L. Bobay, Regina Conway-Philips, Ronda G. Hughes, Linda L. Costa, Sarah J. Bahr, Danielle M. Siclovan, Susan A. Nuccio, Marianne E. Weiss
College of Nursing Faculty Research and Publications
Aim
To describe clinical nurses' experiences with practice change associated with participation in a multi‐site nursing translational research study implementing new protocols for hospital discharge readiness assessment.
Background
Nurses' participation in translational research studies provides an opportunity to evaluate how implementation of new nursing interventions affects care processes within a local context. These insights can provide information that leads to successful adoption and sustainability of the intervention.
Methods
Semi‐structured focus groups from 30 of 33 participating study hospitals lead by team nurse researchers.
Results
Nurses reported improved and earlier awareness of patients' discharge needs, changes in discharge practices, greater patient/family …
Living The Manatt Report: Advancing The Future Of Nursing Through Joint Academic Appointments, Jennifer K. Pfister, Jill C. Kuester, Katie Mcdermott, Leslie Talbert, Christine A. Schindler
Living The Manatt Report: Advancing The Future Of Nursing Through Joint Academic Appointments, Jennifer K. Pfister, Jill C. Kuester, Katie Mcdermott, Leslie Talbert, Christine A. Schindler
College of Nursing Faculty Research and Publications
In 2016, the American Association of Colleges of Nursing published the Manatt Report which outlines recommendations to address the future of academic nursing. This report asserts that in order to influence the direction of healthcare, academic nursing needs to partner with academic health centers in leadership positions, embrace current clinical practice, and prioritize research. The following paper details the successful implementation of joint academic appointments between a college of nursing and a medical college. Joint appointments have formalized the role of clinician-educator, brought current clinical knowledge to academia, and allowed for protected academic time that is focused on enhancing the …
Blood Flow Improvement Trial: Design And Enrollment Developing Topics, Maiya F. Macalpine, Margo B. Heston, Julian M. Gaitán, Ozioma C. Okonkwo, Barbara B. Bendlin, Kimberlee A. Gretebeck, Randall J. Gretebeck
Blood Flow Improvement Trial: Design And Enrollment Developing Topics, Maiya F. Macalpine, Margo B. Heston, Julian M. Gaitán, Ozioma C. Okonkwo, Barbara B. Bendlin, Kimberlee A. Gretebeck, Randall J. Gretebeck
College of Nursing Faculty Research and Publications
Background
Midlife insulin resistance (IR) has previously been shown to be associated with lower cerebral blood flow (CBF), and is a potentially modifiable risk factor for dementia. The Blood Flow Improvement Trial (BFiT), NCT03117829 , tested a 12 week carbohydrate restricted diet (CRD) and exercise behavioral intervention to reverse IR, and aimed to 1) determine the extent to which improving or normalizing glucose homeostasis improves CBF and cognitive function in individuals with IR, 2) determine whether participants continue to maintain improved or normalized glycemic control for 6 months, and 3) determine changes in the human metabolome as individuals improve or …
Budget Impact Analysis Of Robotic Exoskeleton Use For Locomotor Training Following Spinal Cord Injury In Four Sci Model Systems, Daniel Pinto, Mauricio Garnier-Villarreal, Jason Barbas, Shuo-Hsiu Chang, Susan Charlifue, Edelle C. Field-Fote, Catherine L. Furbish, Candy Tefertiller, Chaithanya K. Mummidisetty, Heather Taylor, Arun Jayaraman, Allen W. Heinemann
Budget Impact Analysis Of Robotic Exoskeleton Use For Locomotor Training Following Spinal Cord Injury In Four Sci Model Systems, Daniel Pinto, Mauricio Garnier-Villarreal, Jason Barbas, Shuo-Hsiu Chang, Susan Charlifue, Edelle C. Field-Fote, Catherine L. Furbish, Candy Tefertiller, Chaithanya K. Mummidisetty, Heather Taylor, Arun Jayaraman, Allen W. Heinemann
College of Nursing Faculty Research and Publications
Background
We know little about the budget impact of integrating robotic exoskeleton over-ground training into therapy services for locomotor training. The purpose of this study was to estimate the budget impact of adding robotic exoskeleton over-ground training to existing locomotor training strategies in the rehabilitation of people with spinal cord injury.
Methods
A Budget Impact Analysis (BIA) was conducted using data provided by four Spinal Cord Injury (SCI) Model Systems rehabilitation hospitals. Hospitals provided estimates of therapy utilization and costs about people with spinal cord injury who participated in locomotor training in the calendar year 2017. Interventions were standard of …
Parent Readiness For Hospital Discharge Scale: Psychometrics And Association With Postdischarge Outcomes, Marianne E. Weiss, Stacee M. Lerret, Rachel Schiffman
Parent Readiness For Hospital Discharge Scale: Psychometrics And Association With Postdischarge Outcomes, Marianne E. Weiss, Stacee M. Lerret, Rachel Schiffman
College of Nursing Faculty Research and Publications
Introduction The purpose of this study is to validate the Readiness for Hospital Discharge Scale (RHDS) for use with parents of hospitalized children. PedRHDS is a structured tool for a discharge readiness assessment before pediatric discharge. Methods Using combined data from four studies with 417 parents, psychometric testing and item reduction proceeded with principal component analysis for factor structure delineation, Cronbach's alpha for reliability estimation, and regression analysis for predictive validity. Results A 23-item PedRHDS retained the a priori factor structure. Reliability ranged from 0.73 to 0.85 for the 23-item and 10- and 8-item short scales. PedRHDS (all forms) was …
Rural Malawian Women’S Resistance To Systematic Oppression, Violence, And Abuse By Their Husbands, Lucy Mkandawire-Valhmu, Wendy S. Bauer, Patricia E. Stevens, Loren W. Galvao, Katarina M. Grande, April Yerges, Lindsay Emer, Thokozani Mwenyekonde, Lance Weinhardt
Rural Malawian Women’S Resistance To Systematic Oppression, Violence, And Abuse By Their Husbands, Lucy Mkandawire-Valhmu, Wendy S. Bauer, Patricia E. Stevens, Loren W. Galvao, Katarina M. Grande, April Yerges, Lindsay Emer, Thokozani Mwenyekonde, Lance Weinhardt
College of Nursing Faculty Research and Publications
In Malawi, 41% of women aged 15 to 49 report ever experiencing intimate partner violence (IPV). Although there is evidence of the pervasiveness of IPV in Malawian society, the context in which it occurs and how women respond is not well described. The purpose of this study was to describe experiences of IPV of rural Malawian women. In-depth interviews were conducted with 55 rural Malawian women aged 21 to 75 years (M = 39) as part of a larger, mixed-methods study. This qualitative thematic analysis highlights husbands’ IPV against wives and women’s actions to protect themselves and their children, …
Non-Song Vocalizations Of Humpback Whales In Western Australia, Angela Recalde-Salas, Christine Erbe, Chandra Salgado Kent, Miles Parsons
Non-Song Vocalizations Of Humpback Whales In Western Australia, Angela Recalde-Salas, Christine Erbe, Chandra Salgado Kent, Miles Parsons
Research outputs 2014 to 2021
This study presents non-song vocalizations of humpback whales (Megaptera novaeangliae) from two migratory areas off the Western Australian coast: Geographe Bay and Port Hedland. A total of 220 sounds were identified as non-song sounds in 193 h of recordings reviewed. Of those, 68 were measured and qualitatively classified into 17 groups using their spectral features. One group (HW-02) had a high level of variation in terms of spectral slope. However, further classification using statistical classification methods was not possible because of the small sample size. Non-song sound frequencies varied from 9 Hz to 6 kHz, with the majority of sounds …
First Age- And Gender-Matched Case-Control Study In Australia Examining The Possible Association Between Toxoplasma Gondii Infection And Type 2 Diabetes Mellitus: The Busselton Health Study, Aus Molan, Kazunori Nosaka, Michael Hunter, Jinxia Zhang, Xiaoni Meng, Manshu Song, Wei Wang
First Age- And Gender-Matched Case-Control Study In Australia Examining The Possible Association Between Toxoplasma Gondii Infection And Type 2 Diabetes Mellitus: The Busselton Health Study, Aus Molan, Kazunori Nosaka, Michael Hunter, Jinxia Zhang, Xiaoni Meng, Manshu Song, Wei Wang
Research outputs 2014 to 2021
An emerging field of research is starting to examine the association of infectious pathogens with type 2 diabetes mellitus (T2DM). An understudied parasite of interest is Toxoplasma gondii. Globally, very few studies have been conducted to investigate this association. Additionally, very little data exists on the prevalence of T. gondii in the general Australian population. Our group sought to determine the prevalence, association, and risk factors between T. gondii infection and T2DM from a representative Australian human population. Through a cross-sectional, age-A nd gender-matched case-control study, 150 subjects with T2DM together with 150 control subjects from the Busselton Health Study …
Leak Location Based On Pds-Vmd Of Leakage-Induced Vibration Signal Under Low Snr In Water-Supply Pipelines, Shuaiyong Li, Chuanqiang Xia, Zhenhua Cheng, Weipei Mao, Ying Liu, Daryoush Habibi
Leak Location Based On Pds-Vmd Of Leakage-Induced Vibration Signal Under Low Snr In Water-Supply Pipelines, Shuaiyong Li, Chuanqiang Xia, Zhenhua Cheng, Weipei Mao, Ying Liu, Daryoush Habibi
Research outputs 2014 to 2021
Leak location in water-supply pipelines is of great significance in order to preserve water resources and reduce economic losses. Cross-correlation (CC) based leak location is a popular and effective method in water-supply pipelines (WSP). However, with a decrease of signal to noise ratio (SNR), the errors of time-delay estimation (TDE) based on CC will become larger making it almost impossible to determine a leakage position. Hence, this work proposes leak location based on a combination of phase difference spectrum and variational mode decomposition (PDS-VMD) of leakage-induced vibration signal under low SNR for WSP. Firstly, the leakage-induced vibration signal is decomposed …
Role Of Vegetated Coastal Ecosystems As Nitrogen And Phosphorous Filters And Sinks In The Coasts Of Saudi Arabia, V. Saderne, M. Cusack, Oscar Serrano, H. Almahasheer, P. K. Krishnakumar, L. Rabaoui, M. A. Qurban, C. M. Duarte
Role Of Vegetated Coastal Ecosystems As Nitrogen And Phosphorous Filters And Sinks In The Coasts Of Saudi Arabia, V. Saderne, M. Cusack, Oscar Serrano, H. Almahasheer, P. K. Krishnakumar, L. Rabaoui, M. A. Qurban, C. M. Duarte
Research outputs 2014 to 2021
Vegetated coastal ecosystems along the Red Sea and Arabian Gulf coasts of Saudi Arabia thrive in an extremely arid and oligotrophic environment, with high seawater temperatures and salinity. Mangrove, seagrass and saltmarsh ecosystems have been shown to act as efficient sinks of sediment organic carbon, earning these vegetated ecosystems the moniker 'blue carbon' ecosystems. However, their role as nitrogen and phosphorus (N and P) sinks remains poorly understood. In this study, we examine the capacity of blue carbon ecosystems to trap and store nitrogen and phosphorous in their sediments in the central Red Sea and Arabian Gulf. We estimated the …
Assessing The Efficacy Of Tnf-Alpha Inhibitors In Preventing Emergency And Emergent Colectomies, Ruben Rajan, Matthew W. Trinder, Johnny Lo, Mary Theophilus
Assessing The Efficacy Of Tnf-Alpha Inhibitors In Preventing Emergency And Emergent Colectomies, Ruben Rajan, Matthew W. Trinder, Johnny Lo, Mary Theophilus
Research outputs 2014 to 2021
Background and Aim: Severe ulcerative colitis (UC) is potentially life threatening and is associated with significant morbidity. TNF-∝ inhibitors (Infliximab) were introduced in Australia for the management of medically resistant, acute, severe flares of UC in 2008. The aim of this study is to assess the efficacy of Infliximab in preventing emergent and emergency colectomies for patients with moderate to severe UC by comparing colectomy rates before and after its introduction at our institution. Methods: This was a retrospective cohort study of all patients who were admitted to the Royal Perth Hospital with a flare of UC between 2002 and …
“Notame”: Workflow For Non-Targeted Lc-Ms Metabolic Profiling, Anton Klåvus, Marietta Kokla, Stefania Noerman, Ville M. Koistinen, Marjo Tuomainen, Iman Zarei, Topi Meuronen, Merja R. Häkkinen, Soile Rummukainen, Ambrin Farizah Babu, Taisa Sallinen, Olli Karkkainen, Jussi Paananen, David Broadhurst, Carl Brunius, Kati Hanhineva, Hanhineva
“Notame”: Workflow For Non-Targeted Lc-Ms Metabolic Profiling, Anton Klåvus, Marietta Kokla, Stefania Noerman, Ville M. Koistinen, Marjo Tuomainen, Iman Zarei, Topi Meuronen, Merja R. Häkkinen, Soile Rummukainen, Ambrin Farizah Babu, Taisa Sallinen, Olli Karkkainen, Jussi Paananen, David Broadhurst, Carl Brunius, Kati Hanhineva, Hanhineva
Research outputs 2014 to 2021
Metabolomics analysis generates vast arrays of data, necessitating comprehensive workflows involving expertise in analytics, biochemistry and bioinformatics in order to provide coherent and high-quality data that enable discovery of robust and biologically significant metabolic findings. In this protocol article, we introduce notame, an analytical workflow for non-targeted metabolic profiling approaches, utilizing liquid chromatography-mass spectrometry analysis. We provide an overview of lab protocols and statistical methods that we commonly practice for the analysis of nutritional metabolomics data. The paper is divided into three main sections: the first and second sections introducing the background and the study designs available for metabolomics research …