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2020

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The Dietary Decision-Making Process Of Women In Nigeria, Gachomo Joanne Mapis Jan 2020

The Dietary Decision-Making Process Of Women In Nigeria, Gachomo Joanne Mapis

Walden Dissertations and Doctoral Studies

Nigerians have been opting for a more processed Western diet. These changes in dietary choices have aligned with obesity and undernutrition, attributable to micronutrient deficiencies or malnutrition. Many scholars have presented varying intervention strategies ranging from consumption of a variety of foods containing the necessary micronutrients to food fortification. The purpose of this grounded theory study was to explore the perceptions of women in an urban city in Nigeria on indigenous foods and Western dietary influences to determine social interactions, the consequence of the interactions, and the women’s current perceptions of food choices. The social-ecological model was used to explore …


An Autoencoder And Artificial Neural Network-Based Method To Estimate Parity Status Of Wild Mosquitoes From Mear-Infrared Spectra, Masabho Peter Milali, Samson S. Kiware, Nicodem J. Govella, Fredros Okumu, Naveen K. Bansal, Serdar Bozdag, Jacques D. Charlwood, Marta F. Maia, Sheila B. Ogoma, Floyd E. Dowell, George Corliss, Maggy T. Sikulu-Lord, Richard J. Povinelli Jan 2020

An Autoencoder And Artificial Neural Network-Based Method To Estimate Parity Status Of Wild Mosquitoes From Mear-Infrared Spectra, Masabho Peter Milali, Samson S. Kiware, Nicodem J. Govella, Fredros Okumu, Naveen K. Bansal, Serdar Bozdag, Jacques D. Charlwood, Marta F. Maia, Sheila B. Ogoma, Floyd E. Dowell, George Corliss, Maggy T. Sikulu-Lord, Richard J. Povinelli

Mathematical and Statistical Science Faculty Research and Publications

After mating, female mosquitoes need animal blood to develop their eggs. In the process of acquiring blood, they may acquire pathogens, which may cause different diseases in humans such as malaria, zika, dengue, and chikungunya. Therefore, knowing the parity status of mosquitoes is useful in control and evaluation of infectious diseases transmitted by mosquitoes, where parous mosquitoes are assumed to be potentially infectious. Ovary dissections, which are currently used to determine the parity status of mosquitoes, are very tedious and limited to few experts. An alternative to ovary dissections is near-infrared spectroscopy (NIRS), which can estimate the age in days …


Health Outcomes Associated With Gulf War Illness, Shannon K. Barth Jan 2020

Health Outcomes Associated With Gulf War Illness, Shannon K. Barth

Graduate Theses, Dissertations, and Problem Reports (ETD)

Background:

Nearlythirty years after the 1990-1991 Persian Gulf War a definitive case definition for Gulf War Illness (GWI) is lacking. The objective is to explore health outcomes associated with GWI using currently accepted classifications in order to better understand GWI by examining pre-war medical conditions as predictors of probable GWI, mortality outcomes of veterans with probable GWI, and female-specific medical conditions among women with probable GWI. Additionally, we utilize an alternative GWI case definition.

Methods:

Data come from theDepartment of Veterans Affairs (VA)1995-1997 National Health Survey of Persian Gulf War Era Veterans, a population-based survey of deployed …


Immunity Passports And Moral Hazard, Daniel J. Hemel, Anup Malani Jan 2020

Immunity Passports And Moral Hazard, Daniel J. Hemel, Anup Malani

Coase-Sandor Institute for Law & Economics Research Paper Series

The idea of using “immunity passports” to restart the economy before the arrival of a SARS-CoV-2 vaccine has attracted increasing attention as the Covid-19 crisis has escalated. Under an “immunity passport” regime, individuals who test positive for SARS-CoV-2 antibodies would receive certificates allowing them to return to work and potentially to participate in a broader range of activities without social distancing. One concern raised by the “immunity passport” proposal is that not-yet-infected individuals would have an incentive to expose themselves to the virus intentionally so that they can develop antibodies and obtain passports. This paper evaluates the moral-hazard risk that …


Evaluation Of The Tuberculosis Management Program In Ghana, Boampong Akese Jan 2020

Evaluation Of The Tuberculosis Management Program In Ghana, Boampong Akese

Walden Dissertations and Doctoral Studies

Tuberculosis (TB) is a major health issue estimated to be affecting about 1/3 of the world’s population. TB is a major health problem in Ghana primarily because of weak health infrastructure and poor TB case detection and management practices. Measuring and evaluating the performance of health programs is an important aspect of health care services in any country. The purpose of this quantitative study was to evaluate the TB management program in Ghana. A cross-sectional research design was used to answer the research questions. Secondary data were obtained from the Ghana District Health Information Management System database. The theoretical foundation …


Can Farmers And Bats Co-Exist? Farmer Attitudes, Knowledge, And Experiences With Bats In Belize, Hannah G. Shapiro, Adam S. Willcox, Mallory Tate, Emma V. Willcox Jan 2020

Can Farmers And Bats Co-Exist? Farmer Attitudes, Knowledge, And Experiences With Bats In Belize, Hannah G. Shapiro, Adam S. Willcox, Mallory Tate, Emma V. Willcox

Human–Wildlife Interactions

Bats (Chiroptera) are often viewed negatively by the public. Negative public perceptions of bats may hinder efforts to conserve declining populations. In Belize, the presence of vampire bats (Desmodus rotundus and Diphylla ecaudata) exacerbates the potential for conflicts with humans because of the increased rabies transmission risks. To mitigate these risks, the Belize government provides farmers with assistance to trap and remove vampire bats. In June 2018, we surveyed farmers (n = 44) in and adjacent to the Vaca Forest Reserve in Belize to learn more about their attitudes, knowledge, and experiences with bats. This information may …


Maintaining Effective Infection Control Protocol, Lauren Eusner, Kimberly Lintag Jan 2020

Maintaining Effective Infection Control Protocol, Lauren Eusner, Kimberly Lintag

Dental Hygiene Faculty Publications

The safety of clinicians and patients in the dental office rests on adherence to evidence-based infection control standards.


Focused Deterrence Violence Prevention At Community And Individual Levels, Edmund F. Mcgarrell Jan 2020

Focused Deterrence Violence Prevention At Community And Individual Levels, Edmund F. Mcgarrell

Marquette Law Review

The focused deterrence violence prevention model emerged as part of Boston Ceasefire in the mid-1990s. Since that time, solid research evidence has emerged indicating focused deterrence can influence community levels of violence, particularly gang- and group-related violence. It is considered an evidence-based violence reduction strategy. The evidence of the impact on individuals, however, is much more limited and mixed. This Article presents the focused deterrence model, reviews the research evidence and considers the implications for reducing violent recidivism. Several lingering research questions as well as considerations for leveraging focused deterrence along with other recidivism reduction strategies are discussed.


Preprint (Medicine & Pharmacology, Preprints.Org): Avoiding Covid-19 Complications With Diabetic Patients Could Be Achieved By Multi-Dose Bcg Vaccine: A Case Study Of Beta Cells Regeneration By Serendipity, Bassam Ayoub, Eman Ramadan, Nermeen Ashoush, Mariam M. Tadros, Moataz S. Hendy, Mohamed M. Elmazar, Shaker Mousa Jan 2020

Preprint (Medicine & Pharmacology, Preprints.Org): Avoiding Covid-19 Complications With Diabetic Patients Could Be Achieved By Multi-Dose Bcg Vaccine: A Case Study Of Beta Cells Regeneration By Serendipity, Bassam Ayoub, Eman Ramadan, Nermeen Ashoush, Mariam M. Tadros, Moataz S. Hendy, Mohamed M. Elmazar, Shaker Mousa

Pharmacy

No abstract provided.


Virus Purification Framework And Enhancement In Aqueous Two-Phase System, Pratik Umesh Joshi Jan 2020

Virus Purification Framework And Enhancement In Aqueous Two-Phase System, Pratik Umesh Joshi

Dissertations, Master's Theses and Master's Reports

Viral infections regularly pose detrimental health risks to humans. Preventing viral infections through global immunization requires the production of large doses of vaccines. The increasing demand for vaccines, especially during pandemics such as COVID-19, has challenged current manufacturing strategy to develop advanced unit operations with high throughput capability. Over the decade, the upstream processing responsible for synthesizing viral products in cell cultures has shown significant success in yielding high titers of viruses and virus-like particles. The progress in the upstream stage has now shifted the bottleneck to the downstream processing (DSP). Overlooked for decades, the DSP responsible for viral product …


Recovering From Covid-19 Building Closures: Guidance Document, David Krause, Cheri Marcham, John Springston, Alex Lebeau, Robert Rottersman, Timothy Froehlig, Bart Ashley Jan 2020

Recovering From Covid-19 Building Closures: Guidance Document, David Krause, Cheri Marcham, John Springston, Alex Lebeau, Robert Rottersman, Timothy Froehlig, Bart Ashley

Publications

While the country comes to terms with the inevitable impact that SARS-CoV-2, the virus that causes COVID-19, will have on our lives and communities, public health authorities remain focused on breaking the chain of transmission. Managing the risk has resulted in widespread closures of businesses, schools, universities, resorts, and other facilities deemed “non-essential.” Practically speaking, this means closing buildings and ceasing operations. For building owners and operators, this poses a significant challenge to protect their assets and to ensure they are ready to reoccupy once the pandemic subsides.


Risk Factors Associated With Infection Of Blood-Borne Virus Among People Who Used Methamphetamine, Yilin Cai, Sijin Wen, Ruchi Bhandari Jan 2020

Risk Factors Associated With Infection Of Blood-Borne Virus Among People Who Used Methamphetamine, Yilin Cai, Sijin Wen, Ruchi Bhandari

Faculty & Staff Scholarship

Background

The surge of methamphetamine use has been a complicating factor compounding the steeply increasing number of drug overdose deaths in the U.S. Infection from blood-borne viruses including hepatitis B virus (HBV), hepatitis C virus (HCV) and HIV, related to methamphetamine use continue to grow. This study aims to examine the risk factors associated with HBV, HCV and HIV among people who used methamphetamine.

Methods

People who ever used methamphetamine were identified from five National Health and Nutrition Examination Survey (NHANES) cohorts, 2007 to 2016. The outcome was either positive or negative for blood-borne viruses as identified from laboratory tests. …


The Antiviral Activity Of Lichen Metabolites Against Dengue Virus, Naphat Loeanurit Jan 2020

The Antiviral Activity Of Lichen Metabolites Against Dengue Virus, Naphat Loeanurit

Chulalongkorn University Theses and Dissertations (Chula ETD)

Dengue fever is one of the mosquito-borne infectious diseases globally. Currently, no specific treatment was established. Depsidones and depsides are one of the most common lichen secondary metabolites produced for the organism’s survival in extreme environments. These compounds have been reported as antivirals against the other virus in Flaviviridae family, hepatitis C virus. In this study, depsidones and depsides were explored for anti-dengue efficacy and cellular toxicity. One depsidone, VK-0014, and two depsides, TT-031 and TT-032, exhibited an anti-DENV2 with effective concentration (EC50) of 17.42 ± 3.21, 2.43 ± 0.19, and 0.91 ± 0.15 µM, respectively. Cytotoxicity concentration (CC50) in …


Genome-Wide Identification Of Chiari Malformation Type I Associated Candidate Genes And Chromosomal Variations, Ti̇muçi̇n Avşar, Şeyma Çaliş, Baran Yilmaz, Gülden Demi̇rci̇ Otluoğlu, Can Holyavki̇n, Türker Kiliç Jan 2020

Genome-Wide Identification Of Chiari Malformation Type I Associated Candidate Genes And Chromosomal Variations, Ti̇muçi̇n Avşar, Şeyma Çaliş, Baran Yilmaz, Gülden Demi̇rci̇ Otluoğlu, Can Holyavki̇n, Türker Kiliç

Turkish Journal of Biology

Chiari malformation type I (CMI) is a brain malformation that is characterized by herniation of the cerebellum into the spinal canal. Chiari malformation type I is highly heterogeneous; therefore, an accurate explanation of the pathogenesis of the disease is often not possible. Although some studies showed the role of genetics in CMI, the involvement of genetic variations in CMI pathogenesis has not been thoroughly elucidated. Therefore, in the current study we aim to reveal CMI-associated genomic variations in familial cases. Four CMI patients and 7 unaffected healthy members of two distinct families were analyzed. A microarray analysis of the affected …


Cultured Meat Could Prevent The Next Pandemic, Jonathan Anomaly Jan 2020

Cultured Meat Could Prevent The Next Pandemic, Jonathan Anomaly

Animal Sentience

Wiebers & Feigin identify intensive agriculture and trade in exotic animals as the main sources of novel zoonotic viral infections. They recommend a transition away from meat. I would add that we would do well to invest in the mass production of cultured meat, derived from stem cells, as a radical alternative to animal agriculture.


Homelessness And Hiv Risk: Experiences, Perceptions, And Beliefs Of Transgender Youth, Darcia Bryden-Currie Jan 2020

Homelessness And Hiv Risk: Experiences, Perceptions, And Beliefs Of Transgender Youth, Darcia Bryden-Currie

Walden Dissertations and Doctoral Studies

Human ImmunodeficiencyVirus (HIV) continues to be a public health concern in the United States, with increased rates of infection among transgender youth. The phenomenon of homelessness is also a significant challenge for transgender youth. Gender expression often results in stigma, and discrimination, many trans youth experience poverty, rejection, and low self-esteem, which are precursors to homelessness. The purpose of this qualitative phenomenological study was to explore the influence that homelessness has on sexual risk associated behaviors in transgender youth. The theoretical framework that guided this study was Bandura’s social cognitive theory. The research questions sought to explore how this population …


Black Lives Matter: A Conversation On Health And Criminal Justice Disparities, Franciska Coleman, Aval-Naree S. Green Jan 2020

Black Lives Matter: A Conversation On Health And Criminal Justice Disparities, Franciska Coleman, Aval-Naree S. Green

University of Maryland Law Journal of Race, Religion, Gender and Class

No abstract provided.


West Virginia's Model Of Buprenorphine Expansion: Preliminary Results, Erin L Winstanley, Laura R Lander, James H Berry, James J Mahoney, Wanhong Zheng, Jeremy Herschler, Patrick Marshalek, Sheena Sayres, Jay Mason, Marc W Haut Jan 2020

West Virginia's Model Of Buprenorphine Expansion: Preliminary Results, Erin L Winstanley, Laura R Lander, James H Berry, James J Mahoney, Wanhong Zheng, Jeremy Herschler, Patrick Marshalek, Sheena Sayres, Jay Mason, Marc W Haut

Project ECHO Bibliography

West Virginia (WV) is situated at the epicenter of the opioid epidemic with the highest rates of overdose deaths and some of the lowest rates of access to life saving evidence-based medication assisted treatment (MAT) for patients with opioid use disorder (OUD). WV used a modified hub-and-spoke model to build organizational capacity for facilities to use buprenorphine to treat patients with OUD and to provide ongoing case consultation. The purpose of this study is to 1) describe the group-base model of buprenorphine treatment and the model used to build organizational capacity, 2) to describe the preliminary results of buprenorphine expansion …


The Immigrant Population Amid Covid-19 Pandemic Crisis: A Compiled Project For Nurs 518, Maureen S. Reyes Jan 2020

The Immigrant Population Amid Covid-19 Pandemic Crisis: A Compiled Project For Nurs 518, Maureen S. Reyes

Population Health

Immigrants has been part of the United States (US) historical society ever since this country has long been discovered. They say that this nation is built by immigrants. Some people would strongly disagree; but to be fair that is a reality. The American economy has long thrive and sustained, and has been strengthened by the contributions made by immigrants. Immigrants come from a variety of cultural and ethnic backgrounds; each with their own stories to tell and traditions to share.

The COVID-19 pandemic has made an impact on the socioeconomic and health care inequities of vulnerable and undeserved communities in …


Alternatives To Red Blood Cell Transfusions, Julia Prosser Jan 2020

Alternatives To Red Blood Cell Transfusions, Julia Prosser

Capstone Showcase

Abstract

Introduction: Allogenic red blood cell (RBC) transfusions are used for a number of different reasons. As with any medical procedure, allogenic RBC transfusions are not risk-free. Since the first recorded blood transfusion in 1655, the process has remained relatively unchanged. ABO incompatibility and contamination with infectious diseases are two major complications associated with RBC transfusions. Furthermore, traditional allogenic RBC transfusions have supply and demand issues. These issues, plus several more, could be alleviated with the use of artificial blood. This paper addresses the important clinical question: In patients who require RBC transfusions (P), is there a viable artificial blood …


Doctor Youtube’S Opinion On Seasonal Influenza: A Critical Appraisal Of The Information Available To Patients, Akhil Kallur, Ahmad Albalbissi, Ismael Carillo-Martin, Boonphiphop Boonpheng, Lakshmi Kallur, Yaman Kherallah, Akhilesh Mahajan, Shayan Mahapatra, Kaushik Mohan, Priyasree Mohan, Keerti Reddy, Pratyaksha Sankhyan, Sonia Lopez-Alvarez, Dima Youssef, Adel M. El Abbassi, Alexei Gonzalez-Estrada Jan 2020

Doctor Youtube’S Opinion On Seasonal Influenza: A Critical Appraisal Of The Information Available To Patients, Akhil Kallur, Ahmad Albalbissi, Ismael Carillo-Martin, Boonphiphop Boonpheng, Lakshmi Kallur, Yaman Kherallah, Akhilesh Mahajan, Shayan Mahapatra, Kaushik Mohan, Priyasree Mohan, Keerti Reddy, Pratyaksha Sankhyan, Sonia Lopez-Alvarez, Dima Youssef, Adel M. El Abbassi, Alexei Gonzalez-Estrada

ETSU Faculty Works

Background: Seasonal influenza is a respiratory illness caused by the influenza virus. During the 2017–2018 flu season, the Centers for Disease Control and Prevention noted approximately 959,000 hospitalizations and 79,400 deaths from influenza. We sought to evaluate the educational quality of informational videos pertaining to seasonal influenza on the popular social media forum, YouTube. Methods: Using the keywords “seasonal influenza,” all videos from 28 January to 5 February 2017 were included and analyzed for characteristics, source, and content. The source was further classified as healthcare provider, alternative-medicine provider, the patient and/or their parents, company, media, or professional society. Videos about …


Relationship Between Economy, Education, Population, Healthcare And Prevalence Of Hiv/Aids In Nigeria, Bernard Odelola Jan 2020

Relationship Between Economy, Education, Population, Healthcare And Prevalence Of Hiv/Aids In Nigeria, Bernard Odelola

All Graduate Theses, Dissertations, and Other Capstone Projects

HIV/AIDS has been described as one of the deadliest epidemics of our lifetime. With the global efforts to scale down the effect of this disease through innovative programs, scientific researches and medical advancement, little success has been recorded in least developed nations. Nigeria is still one of the nations that is yet to achieve huge success in the fight against HIV/AIDS and meet Millennium Development Goal on HIV. Arguably, government needs to intensify more efforts in searching for factors that increase the prevalence of the disease.

To further understand the epidemic, this thesis is designed to study and answer research …


Antibacterial, Antifungal, Antioxidant Activity And Polyphenol Content Of Aerial Parts And Bulbs Of Allium Schugnanicum., Saidbeg Satorov, F. Mirzoeva, Sh. Kurbonbekova, Sh. Satorov, M. Vakhidova, Vyacheslav Dushenkov Jan 2020

Antibacterial, Antifungal, Antioxidant Activity And Polyphenol Content Of Aerial Parts And Bulbs Of Allium Schugnanicum., Saidbeg Satorov, F. Mirzoeva, Sh. Kurbonbekova, Sh. Satorov, M. Vakhidova, Vyacheslav Dushenkov

Publications and Research

Objective: То study of antibacterial, antifungal and antioxidant activity, and content of polyphenols in the bulb and aerial parts of an endemic species of onion A. schugnanicum. Methods: An ethanol-based extract was prepared from fresh plants. Total polyphenolic content (Folin) and ABTS antioxidant capacity assays were used to characterized extracts. Extracts obtained from bulbs, peduncle, and seeds demonstrated antibacterial activity against the reference Staphylococcus aureus (ATCC 4929), Pseudomonas aeruginosa (ATCC 4930) and Klebsiella pneumoniae (ATCC 4927) strains, as well as against the hospital strains of the same types of bacteria, i.e. strains isolated from inpatient surgical patients. Results: The study …


High-Throughput Two-Stage Dereplication Of Cave Bacteria To Discover Novel Antibiotic Compounds, Alexander Archey Jan 2020

High-Throughput Two-Stage Dereplication Of Cave Bacteria To Discover Novel Antibiotic Compounds, Alexander Archey

Williams Honors College, Honors Research Projects

Since their discovery over a century ago, antibiotics have been a staple of combating infectious diseases. However, bacteria develop resistance to antibiotics through a variety of mechanisms. Efforts to identify new antibiotics often fail by discovering already-known antibiotics, or failing to synthesize new antibiotics that are safe for clinical use. The aim of this research was to dereplicate bacteria- to screen for antibiotic production in- normally isolated in cave ecosystems. Using two new technologies, the Antibiotic Resistance Platform (ARP) and a data acquisition and bioinformatics technique (IDBac), my dereplicating method allowed high throughput of bacterial screening for antibiotics. In this …


Critical Issues In Health, Janet R. Heller Jan 2020

Critical Issues In Health, Janet R. Heller

Open Educational Resources

This is a personal health course for today's college student. Topics cover basic information on mental health, nutrition, substance use disorder, violence prevention, chronic diseases, infectious diseases and reproductive health.

Contents include as OER reading list and a sample outline.

A revised syllabus was added on July 28, 2026. The changes were made to reflect more current information.


Insecticidal Effect Of Diatomaceous Earth And Dolomite Powder Against Corn Weevilsitophilus Zeamais Motschulsky, 1855 (Coleoptera: Curculionidae), Alyssa Cristina Oliveira Freitas, Adriana Aparecida Sinopólis Gigliolli, Ronaldo Roberto Tait Caleffe Caleffe, Helio Conte Jan 2020

Insecticidal Effect Of Diatomaceous Earth And Dolomite Powder Against Corn Weevilsitophilus Zeamais Motschulsky, 1855 (Coleoptera: Curculionidae), Alyssa Cristina Oliveira Freitas, Adriana Aparecida Sinopólis Gigliolli, Ronaldo Roberto Tait Caleffe Caleffe, Helio Conte

Turkish Journal of Zoology

Sitophilus zeamais Motschulsky, 1855 (Coleoptera: Curculionidae) which develops inside the grain, is an aggressive pest of stored grains. Here, we evaluated the efficiency of diatomaceous earth (DE), Diatomita CI/325 CX, and dolomite (DOL), Dolomita Dr. Kanyo, against S. zeamais reared on corn under laboratory conditions and observed external alterations on treated insects using scanning electron microscopy (SEM). Insects treated with both DE and DOL were impregnated with particles on the body surface, and they showed 100% mortality after 10 days of exposure. Damages caused by inert dusts may have contributed to dehydration and desiccation, consequently, leading insects to death. Thus, …


Hsp90 Inhibition And Modulation Of The Proteome: Therapeutical Implications For Idiopathic Pulmonary Fibrosis (Ipf), Ruben Manuel Luciano Colunga Biancatelli, Pavel Solopov, Betsy Gregory, John D. Catravas Jan 2020

Hsp90 Inhibition And Modulation Of The Proteome: Therapeutical Implications For Idiopathic Pulmonary Fibrosis (Ipf), Ruben Manuel Luciano Colunga Biancatelli, Pavel Solopov, Betsy Gregory, John D. Catravas

Bioelectrics Publications

Idiopathic Pulmonary fibrosis (IPF) is a catastrophic disease with poor outcomes and limited pharmacological approaches. Heat shock protein 90 (HSP90) has been recently involved in the wound-healing pathological response that leads to collagen deposition in patients with IPF and its inhibition represents an exciting drug target against the development of pulmonary fibrosis. Under physiological conditions, HSP90 guarantees proteostasis through the refolding of damaged proteins and the degradation of irreversibly damaged ones. Additionally, its inhibition, by specific HSP90 inhibitors (e.g., 17 AAG, 17 DAG, and AUY-922) has proven beneficial in different preclinical models of human disease. HSP90 inhibition modulates a complex …


Recapitulating The Bayesian Framework For Neurosurgical Outpatient Care And A Cost-Benefit Analysis Of Telemedicine For Socioeconomically Disadvantaged Patients In The Philippines During The Pandemic, Kevin Paul Ferraris, Jared Paul Golidtum, Brian Karlo W. Zuñiga, Maria C G Bautista, Jose Carlos Alcazaren, Kenny Seng, Joseph Erroll Navarro Jan 2020

Recapitulating The Bayesian Framework For Neurosurgical Outpatient Care And A Cost-Benefit Analysis Of Telemedicine For Socioeconomically Disadvantaged Patients In The Philippines During The Pandemic, Kevin Paul Ferraris, Jared Paul Golidtum, Brian Karlo W. Zuñiga, Maria C G Bautista, Jose Carlos Alcazaren, Kenny Seng, Joseph Erroll Navarro

Graduate School of Business Publications

Objective: In the Philippines during recent months, a neurosurgical center that caters primarily to socioeconomically disadvantaged patients has encountered unprecedented changes in practice patterns brought about by the COVID-19 pandemic. In particular, the usual task of outpatient care has shifted to the telemedicine format, bringing along all of its attendant advantages and gargantuan challenges. The authors sought to determine the responsiveness of this telemedicine setup to the needs of their disadvantaged patients and explored the application of Bayesian inference to enhance the use of teleconsultation in daily clinical decision-making. Methods: The authors used the following methods to assess the telemedicine …


Hypomorphic Si Genetic Variants Are Associated With Childhood Chronic Loose Stools., Bruno P Chumpitazi, Jeffery Lewis, Derick Cooper, Mauro D'Amato, Joel Lim, Sandeep Gupta, Adrian Miranda, Natalie Terry, Devendra Mehta, Ann Scheimann, Molly O'Gorman, Neelesh Tipnis, Yinka Davies, Joel Friedlander, Heather Smith, Jaya Punati, Julie Khlevner, Mala Setty, Carlo Di Lorenzo Jan 2020

Hypomorphic Si Genetic Variants Are Associated With Childhood Chronic Loose Stools., Bruno P Chumpitazi, Jeffery Lewis, Derick Cooper, Mauro D'Amato, Joel Lim, Sandeep Gupta, Adrian Miranda, Natalie Terry, Devendra Mehta, Ann Scheimann, Molly O'Gorman, Neelesh Tipnis, Yinka Davies, Joel Friedlander, Heather Smith, Jaya Punati, Julie Khlevner, Mala Setty, Carlo Di Lorenzo

Manuscripts, Articles, Book Chapters and Other Papers

OBJECTIVE: The SI gene encodes the sucrase-isomaltase enzyme, a disaccharidase expressed in the intestinal brush border. Hypomorphic SI variants cause recessive congenital sucrase-isomaltase deficiency (CSID) and related gastrointestinal (GI) symptoms. Among children presenting with chronic, idiopathic loose stools, we assessed the prevalence of CSID-associated SI variants relative to the general population and the relative GI symptom burden associated with SI genotype within the study population.

METHODS: A prospective study conducted at 18 centers enrolled 308 non-Hispanic white children ≤18 years old who were experiencing chronic, idiopathic, loose stools at least once per week for >4 weeks. Data on demographics, GI …


Identification And Genomic Characterization Of Candidate Starch And Lactate Utilizing Bacteria From The Rumen Of Beef Cattle, Venkata Bandarupalli Jan 2020

Identification And Genomic Characterization Of Candidate Starch And Lactate Utilizing Bacteria From The Rumen Of Beef Cattle, Venkata Bandarupalli

Electronic Theses and Dissertations

The rumen functions as an anaerobic fermentation chamber where microbial communities ferment feedstuffs into SCFAs. These SCFAs are critical to the ruminant host since they fulfill 70% of its energy requirements. In intensive management systems, ruminants are fed with grain-rich diets, which contain high levels of starch that help meet the energy demands of high producing animals. When grain-based diets are fed to ruminants, ruminal amylolytic and lactate metabolizing bacteria predominate. Grain overload can cause rapid production and accumulation of lactate, resulting in proliferation of amylolytic bacteria and death of lactate metabolizing bacteria. Consequently, high lactate levels result in a …