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International Disease Epidemics And The Shadow Economy, Aziz N. Berdiev, Rajeev K. Goel, James W. Saunoris

Economics Faculty Working Papers

Adding to the emerging body of research related to the current coronavirus crisis, this paper studies the impact of disease epidemics on the worldwide prevalence of the shadow or the underground economy. The informal sector undermines compliance with government regulations and lowers tax collections. Our main hypothesis is that epidemics positively impacts the spread of the shadow economy. Using data on nearly 130 nations and nesting the empirical analysis in the broader literature on the drivers of the shadow sector, we find that both the incidence and the intensity of epidemics positively and significantly contribute to the spread of the …

The Greenbook, Faculty Handbook, 2020-2021, Marshall University Academic Affairs

The Greenbook

This book has been published for the faculty of Marshall University for the specified period of time. This book was created by what is now known as Academic Affairs and is for the period of 2020-2021.

Expansion Of A Food Insecurity Scale In Primary Care., Andrea Gibson

Doctor of Nursing Practice Papers

As a household-level economic and social condition defined by limited or uncertain access to inadequate food, food insecurity serves as a health threat. Food security impacts health by increasing the risk of cardiovascular disease, type 2 diabetes, stroke, and several cancers (WHO, 2005). Expansion of the two-item food insecurity screening to a six-item short-form (USDA 6- SF) screening in primary care has the potential to identify and categorize households into three categories of food security, high/marginal, low, or very low. By differentiating food insecurity categories, clients received more appropriate referrals to services aimed at improving food security. During a recent …

Hepatitis A Educational Program In Food Service Workers., Katherine Barker

Doctor of Nursing Practice Papers

Louisville, KY was affected by a significant outbreak of Hepatitis A in 2017-2018. Kentucky consisted of one-third of the national deaths. The outbreak influenced not only human mortality but had an economic impact on the food service industry. Many restaurants were affected, and some were forced to close due to Hepatitis A outbreaks. To address this issues, a two-step educational process was designed for management to gain understanding of hepatitis A content. The first step was to survey staff (kitchen staff, waiters/waitress, busier, etc.) to determine the compliance rate and variables that influence the compliance rate for vaccination of Hepatitis …

Attitudes, Behaviours, And The Well-Being Of Older Singaporeans In The Time Of Covid-19: Perspectives From The Singapore Life Panel, Paulin T. Straughan, William Tov, Seonghoon Kim, Terence Cheng, Stephen Hoskins, Micah Tan

ROSA Research Briefs

COVID-19 has affected all Singaporeans, regardless of age and socioeconomic status (SES). Many measures have been implemented by the government to control the spread of this disease, including restrictions on social gatherings, restrictions on overseas travel, and making it compulsory to wear a mask. Measures have also included a partial lockdown – known as the ‘circuit breaker’ – which began in April 2020. This forced Singaporeans to quickly adapt to a new normal with some doing better than others. This research brief provides an overview of how COVID-19 and its related measures have affected seniors in Singapore using data from …

Hiv/Hcv Screening Protocols In The Emergency Department., Adrianne Warren Johnson

Doctor of Nursing Practice Papers

Background: The United States is experiencing an epidemic of opioid drug use that has increased the number of people who inject drugs (PWID). This has resulted in an increase in the risk of transmission of blood-borne pathogens including human immunodeficiency virus (HIV) and hepatitis C virus (HCV) among this population. Although injection drug use has surpassed sexual transmission as the leading risk factor for HIV, PWID have the least access to HIV prevention, testing, treatment, and healthcare. Current guidelines recommend testing individuals from high-risk populations for HIV/HCV every six months. Offering routine, opt-out, targeted, bundled HIV/HCV testing in an emergency …

Macalester Today Summer 2020, Macalester College

Macalester Today

No abstract provided.

Measuring Health Related Quality Of Life For Dengue Patients In Iquitos, Peru, William H. Elson, Amy R. Riley-Powell, Amy C. Morrison, Esther E. Gotlieb, Erik J. Groessl, Jhonny J. Cordova, J. Esther Rios, W. Lorena Quiroz, Alfonso S. Vizcarra, Robert C. Reiner, Christopher M. Barker, Gonzalo M. Vazquez-Prokopec, Thomas W. Scott, Alan L. Rothman, John P. Elder, Valerie A. Paz-Soldan

Cell and Molecular Biology Faculty Publications

Previous studies measuring the health-related quality of life (HRQoL) of individuals with dengue focused on treatment seeking populations. However, the vast majority of global dengue cases are unlikely to be detected by health systems. Representative measurements of HRQoL should therefore include patients with disease not likely to trigger treatment-seeking behavior. This study based in Iquitos, Peru used the Quality of Wellbeing Scale-Self Administered, a survey that enquires about not only physical health, but also psychological health, self-care, mobility, and usual social activities, and rates HRQoL between 0 (death) and 1 (optimum function), to evaluate the impact of dengue on HRQoL. …

An Innovative, Prospective, Hybrid Cohort-Cluster Study Design To Characterize Dengue Virus Transmission In Multigenerational Households In Kamphaeng Phet, Thailand, Kathryn B. Anderson, Darunee Buddhari, Anon Srikiatkhachorn, Gregory D. Gromowski, Sopon Iamsirithaworn, Alden L. Weg, Damon W. Ellison, Louis Macareo, Derek A T Cummings, In-Kyu Yoon, Ananda Nisalak, Alongkot Ponlawat, Stephen J. Thomas, Stefan Fernandez, Richard G. Jarman, Alan L. Rothman, Timothy P. Endy

Cell and Molecular Biology Faculty Publications

Difficulties inherent in the identification of immune correlates of protection or severe disease have challenged the development and evaluation of dengue vaccines. There persist substantial gaps in knowledge about the complex effects of age and sequential dengue virus (DENV) exposures on these correlations. To address these gaps, we were conducting a novel family-based cohort-cluster study for DENV transmission in Kamphaeng Phet, Thailand. The study began in 2015 and is funded until at least 2023. As of May 2019, 2,870 individuals in 485 families were actively enrolled. The families comprise at least 1 child born into the study as a newborn, …

A Comparison Efficacy Study Of Commercial Nasopharyngeal Swabs Versus A Novel 3d Printed Swab For The Detection Of Sars-Cov-2, Forest W. Arnold, Gerald Grant, Phillip F. Bressoud, Stephen P. Furmanek, Donghoon Chung, Nadine Sbaih, Dipan Karmali, Meredith Cahill, George Pantalos

The University of Louisville Journal of Respiratory Infections

Introduction: The large volume of diagnostic tests required by the response to the COVID-19 pandemic resulted in a shortage of commercial nasopharyngeal swabs. In an effort to alleviate the shortage, swabs created by 3D printing may be a solution.

Methods: We designed and produced 3D printed swabs and sought to compare their ability to detect SARS-CoV-2 in patients admitted for COVID-19 or who were suspected of having COVID-19.

Results: A total of 30 patients were swabbed with a commercial and a 3D printed swab. Results matched in 27 of 30 patients (90%). Two patients were discordant with a positive commercial …

Cc: Connecticut College Magazine, Summer 2020, Connecticut College

Alumni News/Connecticut College Magazine

No abstract provided.

Improved Antimicrobial Properties Of Silver Nanoparticles With Methylene Blue, Ermek Belekov

Masters Theses & Specialist Projects

Photosensitizing agents are the cornerstone of photodynamic therapy (PDT) that play essential role in deactivation process of multidrug resistant pathogens and tumor treatments. In this work we studied a photosensitizing agent made from mixture of silver nanoparticles (Ag NPs) and methylene blue (MB) which possess improved important characteristics like high photostability and high singlet oxygen yield. Ag NPs were synthesized by pulsed laser ablation technique in different aqueous solutions like Polyvinylpyrrolidone (PVP), citrate and Deionized (DI) water. The synthesized Ag NPs were characterized in depth using with transmission electron microscopy (TEM), UVVisible (UV-Vis), and photoluminescence (PL) spectra. Ag NPs were …

Forevereiu (Summer 2020), Eastern Illinois University Alumni Association

ForeverEIU 2020

No abstract provided.

2020-07-01_Michiganoverview_Covidsymptoms, Michigan Department Of Health & Human Services

Michigan COVID-19 Syndromic Surveillance System Data

The Syndromic Surveillance System Data report was obtained from Michigan's COVID-19 dashboard, from under the link "​Coronavirus Symptoms": https://www.michigan.gov/coronavirus. Data was compiled by the Michigan Department of Health and Human Services (MDHHS). The information was updated daily.

Syndromic Surveillance System data is obtained from approximately 183 facilities participating in syndromic surveillance (132 Emergency Departments (ED), 51 Urgent Cares) across the State of Michigan. The reporting is based on individuals who present at EDs and may not be representative of the overall population. The coronavirus-like symptoms query searches visit free-text (chief complaint, triage notes, and clinical impression) for fever or …

Comparison Of Sars-Cov-2 To Sars-Cov, Mers, And Influenza A: A Systematic Review, Debbie Calabrese

Health Informatics Student Papers and Projects

Differences and similarities are examined among SARS-CoV-2, SARS-CoV-1, MERS and influenza A, in the context of transmissibility. Characteristics specific to the respective pathogens prove invaluable as they set the stage for intervention and management. SARS-CoV-2 bears similarities to other recently emerged infectious diseases in basic virologic ways, yet is distinctly different in terms of viral transmission dynamics. These differences arise from genomic qualities and properties specific to the virus. As ACE2 receptors are determinants for attachment and spread of the virus, and their role throughout tissues in the body is vast, an understanding of organ-level pathogenesis of SARS-CoV-2 is crucial …

Institute Of Public Health Newsletter- Volume1, Issue 2, Institute Of Public Health (Iph) - Cmhs

Institute of Public Health Newsletter (IPHNL) and Other Publications

No abstract provided.

Twenty Year Economic Impacts Of Deworming, Joan Hamory, Michael Kremer, Edward Miguel, Sarah J. Baird, Michael W. Walker

Global Health Faculty Publications

No abstract provided.

Alumni Journal - Volume 91, Number 2, Loma Linda University School Of Medicine

Alumni Journal, School of Medicine

Editorials
2 | From the Editor
4 | From the President
6 | From the Dean

News
8 | School of Medicine News
10 | Alumni News
11 | AIMS Report
12 | Students

Graduation 2020
13 | Graduation Feature: A letter to the graduates, awards, photos, residency information, and more
14 | The Missing Regalia: Debra L. Stottlemyer '86 shares how alumni supported the senior class

Features
30 | Gloves: Hannah C. Lokos '20 tells a story of how she saw a glimpse of God
32 | Department Reports: Emergency Medicine and Urology: E. Lea Walters '94 and Herbert …

Quillen Magazine - Summer 2020, Quillen College Of Medicine, East Tennessee State University

Quillen Magazine

No abstract provided.

How Can Econometrics Help Fight The Covid'19 Pandemic?, Kevin Alvarez, Vladik Kreinovich

Departmental Technical Reports (CS)

The current pandemic is difficult to model -- and thus, difficult to control. In contrast to the previous epidemics whose dynamics was smooth and well described by the existing models, the statistics of the current pandemic is highly oscillating. In this paper, we show that these oscillations can be explained if we take into account the disease's long incubation period -- as a result of which our control measures are determined by outdated data, showing number of infected people two weeks ago. To better control the pandemic, we propose to use the experience of economics, where also the effect of …

Gold & Blue, Spring/Summer 2020, St. Mary's University- San Antonio, Texas

Gold & Blue

This is the Spring/Summer 2020 edition of Gold & Blue which is St. Mary's University's official school publication.

Abstract Book (Pdf), School Of Medicine

Summer Research Internship Program

Abstract Book for the 2020 Summer Research Internship Program.
Participants are listed alphabetically by last name.

Structural Analysis Of The Multifunctional Spoiie Regulatory Protein Of Clostridioides Difficile., Blythe Emily Bunkers

Graduate Theses and Dissertations

Clostridioides (formally Clostridium) difficile is a medically relevant pathogen pertinent to infectious disease research. C. difficile is distinctly known for its ability to produce two toxins, enterotoxin A and cytotoxin B, and the propensity to colonize the mammalian gastrointestinal tract. It is known that metabolism is tightly correlated with sporulation in endospore producers such as C. difficile, but an interesting and novel regulatory relationship found by the Ivey lab has yet to be understood. The relationship explored in this study is observed between the sporulation factor, SpoIIE, which represses expression of an ABC peptide transporter, app. In this study, two …

Sepsis Screening Education, Brittany R. Horn

Doctor of Nursing Practice Scholarly Project

Sepsis is a significant burden to the healthcare field with 1.7 million Americans annually diagnosed with this condition. Earlier diagnosis and treatment are the most effective ways of reducing morbidity and mortality related to sepsis. The current sepsis screening tool in place at Stormont-Vail Hospital, in Topeka, Kansas, is the systemic inflammatory response (SIRS) criteria; however, this screening tool has proven to be less effective than other screening tools available. The screening tools proven more effective than the SIRS criteria, are the quick sequential organ failure assessment (qSOFA) and the sequential organ failure assessment (SOFA). For this project, nursing staff …

Experimental Investigation And Anfis-Based Modelling During Machining Of En31 Alloy Steel, Ishwer Shivakoti, Lewlyn L.R. Rodrigues, Robert Cep, Premendra Mani Pradhan

Open Access archive

This research presents the parametric effect of machining control variables while turning EN31 alloy steel with a Chemical Vapor deposited (CVD) Ti(C, N) + Al2O3 + TiN coated carbide tool insert. Three machining parameters with four levels considered in this research are feed, revolutions per minute (RPM), and depth of cut (ap). The influences of those three factors on material removal rate (MRR), surface roughness (Ra), and cutting force (Fc) were of specific interest in this research. The results showed that turning control variables has a substantial influence on the process responses. Furthermore, the paper demonstrates an adaptive neuro fuzzy …

Kenyon Alumni Magazine - Summer 2020

Kenyon College Alumni Bulletin

No abstract provided.

Emerging Agents For The Treatment Of Chagas Disease: What Is In The Preclinical And Clinical Development Pipeline?, Nieves Martínez-Peinado, Nuria Cortes-Serra, Irene Losada-Galvan, Julio A. Urbina, Ana Rodríguez, John L. Vandeberg, Maria-Jesus Pinazo, Joaquim Gascon, Julio Alonso-Padilla

School of Medicine Publications

Introduction: Chagas disease treatment relies on the lengthy administration of benznidazole and/or nifurtimox, which have frequent toxicity associated. The disease, caused by the parasite Trypanosoma cruzi, is mostly diagnosed at its chronic phase when life-threatening symptomatology manifest in approximately 30% of those infected. Considering that both available drugs have variable efficacy by then, and there are over 6 million people infected, there is a pressing need to find safer, more efficacious drugs.

Areas covered: We provide an updated view of the path to achieve the aforementioned goal. From state-of-the-art in vitro and in vivo assays based on genetically engineered …

Meeting Report Of The Third Annual Tri-Service Microbiome Consortium Symposium, J Philip Karl, Robyn A. Barbato, Laurel A. Doherty, Aarti Gautam, Sarah M. Glaven, Robert J. Kokoska, Dagmar Leary, Rebecca Mickol, Matthew A. Perisin, Andrew J. Hoisington, Edward J. Van Opstal, Vanessa Varaljay, Nancy Kelley-Loughnane, Camilla A. Mauzy, Michael S. Goodson, Jason W. Soares

Faculty Publications

The Tri-Service Microbiome Consortium (TSMC) was founded to enhance collaboration, coordination, and communication of microbiome research among U.S. Department of Defense (DoD) organizations and to facilitate resource, material and information sharing among consortium members. The 2019 annual symposium was held 22–24 October 2019 at Wright-Patterson Air Force Base in Dayton, OH. Presentations and discussions centered on microbiome-related topics within five broad thematic areas: 1) human microbiomes; 2) transitioning products into Warfighter solutions; 3) environmental microbiomes; 4) engineering microbiomes; and 5) microbiome simulation and characterization. Collectively, the symposium provided an update on the scope of current DoD microbiome research efforts, highlighted …

Low Yield Of Hepatitis C Infection In An Outreach Screening Program In Harris County, Texas, Hyun-Seok Kim, Rosalia Guerrero, Shane W Reader, Maria Daheri, Maya Balakrishnan, Catherine L Troisi, Hashem B El-Serag, Aaron P Thrift

Faculty, Staff and Students Publications

A community outreach hepatitis C virus (HCV) infection screening program provided low yield of detecting HCV-infected patients, linking them to our hepatology clinic for treatment. Our data underscore that most of the yield was related to addiction centers and birth cohort; these groups should be targeted by future interventions.

A Phase Ii Single-Arm Study Of Pembrolizumab With Enzalutamide In Men With Metastatic Castration-Resistant Prostate Cancer Progressing On Enzalutamide Alone., Julie N Graff, Tomasz M Beer, Joshi J Alumkal, Rachel E Slottke, William L. Redmond, George V Thomas, Reid F Thompson, Mary A Wood, Yoshinobu Koguchi, Yiyi Chen, Emile Latour, Raymond C Bergan, Charles G Drake, Amy E Moran

Articles, Abstracts, and Reports

BACKGROUND: Checkpoint inhibitors can induce profound anticancer responses, but programmed cell death protein-1 (PD-1) inhibition monotherapy has shown minimal activity in prostate cancer. A published report showed that men with prostate cancer who were resistant to the second-generation androgen receptor inhibitor enzalutamide had increased programmed death-ligand 1 (PD-L1) expression on circulating antigen-presenting cells. We hypothesized that the addition of PD-1 inhibition in these patients could induce a meaningful cancer response.

METHODS: We evaluated enzalutamide plus the PD-1 inhibitor pembrolizumab in a single-arm phase II study of 28 men with metastatic castration-resistant prostate cancer (mprogressing on enzalutamide alone. Pembrolizumab 200 mg …