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2020-09-23_Michiganoverview_Covidsymptoms, Michigan Department Of Health & Human Services

Michigan COVID-19 Syndromic Surveillance System Data

The Syndromic Surveillance System Data report was obtained from Michigan's COVID-19 dashboard, from under the link "​Coronavirus Symptoms": https://www.michigan.gov/coronavirus. Data was compiled by the Michigan Department of Health and Human Services (MDHHS). The information was updated daily.

Syndromic Surveillance System data is obtained from approximately 183 facilities participating in syndromic surveillance (132 Emergency Departments (ED), 51 Urgent Cares) across the State of Michigan. The reporting is based on individuals who present at EDs and may not be representative of the overall population. The coronavirus-like symptoms query searches visit free-text (chief complaint, triage notes, and clinical impression) for fever or …

Forward Together Update [Flu Vaccine], September 23, 2020, University Of Northern Iowa

UNI Response to COVID-19

A memo on the importance of getting a flu shot in 2020.

Antibodies To Variable Domain 4 Linear Epitopes Of The Chlamydia Trachomatis Major Outer Membrane Protein Are Not Associated With Chlamydia Resolution Or Reinfection In Women, Amanda L. Collar, Alexandria C. Linville, Susan B. Core, Cosette M. Wheeler, William M. Geisler, David S. Peabody, Bryce Chackerian, Kathryn M. Frietze

Pathology Research and Scholarship

Chlamydia trachomatis is an obligate intracellular bacterium. C. trachomatis infection is the most prevalent bacterial sexually transmitted infection and can lead to pelvic inflammatory disease and infertility in women. There is no licensed vaccine for C. trachomatis prevention, in part due to gaps in our knowledge of C. trachomatis-specific immune responses elicited during human infections. Previous investigations of the antibody response to C. trachomatis have identified immunodominant antigens and antibodies that can neutralize infection in cell culture. However, epitope-specific responses to C. trachomatis are not well characterized, and the impact of these antibodies on infection outcome is unknown. We …

Population, Development, And Policy, John Bongaarts, Michele Gragnolati, S. Amer Ahmed, Jamaica Corker

Poverty, Gender, and Youth

The extensive literature on population and development yielded few policy-relevant results before the discovery of the demographic dividend. This dividend refers to a rise in per capita income that results from an increase in workers per capita as a population’s fertility declines. This paper describes the role of the demographic dividend in economic development in developing countries and summarizes policy options for strengthening the dividend. The first section reviews the demographic transition with an emphasis on its later phases when declining fertility and a changing population age structure produce the dividend. Next, the demographic drivers of the dividend and its …

A Case Of Streptococcal Surgical Site Infection Following Mohs Surgery, Kami B Lowery, John J Kohorst, C Helen Malone, Ikue Shimizu

Faculty, Staff and Students Publications

Group A β-hemolytic Streptococcal (GAS) cellulitis is an uncommon surgical site infection that presents with rapid onset of pain and swelling in the first few days after a procedure. Unlike staphylococcal cellulitis, GAS cellulitis lacks purulence and spreading erythema. The absence of these classic signs may delay the diagnosis of GAS cellulitis and lead to severe complications. We present the case of an immunosuppressed 49-year-old patient who developed swelling and severe pain at his incision site two days after undergoing Mohs micrographic surgery on his forehead. He was clinically diagnosed with GAS cellulitis and recovered with intravenous antibiotics. Unfortunately, there …

Setting The Standard: Multidisciplinary Hallmarks For Structural, Equitable And Tracked Antibiotic Policy, Claas Kirchhelle, Paul Atkinson, Alex Broom, Komatra Chuengsatiansup, Jorge Pinto Ferreira, Nicolas Fortané, Isabel Frost, Christoph Gradmann, Stephen Hinchliffe, Steven J. Hoffman, Javier Lezaun, Susan Nayiga, Scott H. Podolsky, Kevin Outterson, Stephanie Raymond, Adam P. Roberts, Andrew C. Singer, Anthony D. So, Luechai Sringernyuang, Elizabeth Tayler, Susan Rogers Van Katwyk, Clare I. R. Chandler

Faculty Scholarship

There is increasing concern globally about the enormity of the threats posed by antimicrobial resistance (AMR) to human, animal, plant and environmental health. A proliferation of international, national and institutional reports on the problems posed by AMR and the need for antibiotic stewardship have galvanised attention on the global stage. However, the AMR community increasingly laments a lack of action, often identified as an ‘implementation gap’. At a policy level, the design of internationally salient solutions that are able to address AMR’s interconnected biological and social (historical, political, economic and cultural) dimensions is not straightforward. This multidisciplinary paper responds by …

Temporary Unilateral Hypoglossal Nerve Palsy Secondary To Infectious Mononucleosis: A Case Report., Ashraf Barghash

Future Dental Journal

Tongue paralysis due to isolated palsy of XII cranial nerve is uncommon neurological finding. It is a multi-etiological condition, and may occur secondary to infectious mononucleosis. It is presented with characteristic signs e.g. reduced tongue movements with deviation to the affected side on protrusion. The diagnosis is challenging and based on thorough clinical examination and laboratory and imaging findings. A case of 31year old Kuwaiti male, presented to emergency room at Mubarak Alkabeer Hospital-Kuwait, with infectious mononucleosis complicated with temporary unilateral hypoglossal nerve palsy is reported, with an emphasis that paralysis of cranial nerve may be due to a less …

The Relationship Among Perfectionism, Perceived Stress, And Coping In Baccalaureate Nursing Students, Amanda Finley

Dissertations

Perfectionism in nursing students is an understudied problem that may affect student and workforce success. Perfectionism has been linked to increased stress and less effective coping styles, as well as depression, anxiety and other psychological alterations. However, it has rarely been studied in nursing students. Studying perfectionism in this population is important because it may increase the likelihood that new nurses will struggle with the stress of practice and it could be a significant factor in early career attrition. The purpose of this descriptive, correlational study was to gain a better understanding of the incidence of perfectionism in a nursing …

2020-09-22_Michiganoverview_Covidsymptoms, Michigan Department Of Health & Human Services

Michigan COVID-19 Syndromic Surveillance System Data

The Syndromic Surveillance System Data report was obtained from Michigan's COVID-19 dashboard, from under the link "​Coronavirus Symptoms": https://www.michigan.gov/coronavirus. Data was compiled by the Michigan Department of Health and Human Services (MDHHS). The information was updated daily.

Syndromic Surveillance System data is obtained from approximately 183 facilities participating in syndromic surveillance (132 Emergency Departments (ED), 51 Urgent Cares) across the State of Michigan. The reporting is based on individuals who present at EDs and may not be representative of the overall population. The coronavirus-like symptoms query searches visit free-text (chief complaint, triage notes, and clinical impression) for fever or …

Demographic, Jurisdictional, And Spatial Effects On Social Distancing In The United States During The Covid-19 Pandemic, Rajesh P. Narayanan, James Nordlund, R. Kelley Pace, Dimuthu Ratnadiwakara

Faculty Publications

Social distancing, a non-pharmaceutical tactic aimed at reducing the spread of COVID-19, can arise because individuals voluntarily distance from others to avoid contracting the disease. Alternatively, it can arise because of jurisdictional restrictions imposed by local authorities. We run reduced form models of social distancing as a function of county-level exogenous demographic variables and jurisdictional fixed effects for 49 states to assess the relative contributions of demographic and jurisdictional effects in explaining social distancing behavior. To allow for possible spatial aspects of a contagious disease, we also model the spillovers associated with demographic variables in surrounding counties as well as …

Investigation Of The Sequence-Structure-Activity Relationship In Ponericin L1 From Neoponera Goeldii & Synergistic Interactions Of Ionic Liquids And Antimicrobials To Improve Efficacy, Alexandria S. Senetra

Theses and Dissertations

Non-traditional antimicrobials have been an area of great interest due to the increasing prevalence of antimicrobial resistance (AMR) in bacteria. Antimicrobial peptides (AMPs) & ionic liquids (ILs) are two examples that have been investigated as a potential solution. Most AMPs are naturally derived & exhibit high selectivity against bacterial targets over host cells. The venom-derived peptide, ponericin L1 from Neoponera goeldii, was used to investigate the role of cationic residues & net charge on peptide activity. Using both in vitro & microbiological methods, L1 peptide & derivatives exhibited an alpha-helical conformation with enhanced binding to lipid vesicles containing anionic lipids …

Integrase-Rna Interactions Underscore The Critical Role Of Integrase In Hiv-1 Virion Morphogenesis, Jennifer L. Elliott, Jenna E. Eschbach, Pratibha C. Koneru, Wen Li, Maritza Puray-Chavez, Dana Townsend, Dana Q. Lawson, Alan N. Engelman, Mamuka Kvaratskhelia, Sebla B. Kutluay

Open Access Publications

A large number of human immunodeficiency virus 1 (HIV-1) integrase (IN) alterations, referred to as class II substitutions, exhibit pleiotropic effects during virus replication. However, the underlying mechanism for the class II phenotype is not known. Here we demonstrate that all tested class II IN substitutions compromised IN-RNA binding in virions by one of the three distinct mechanisms: (i) markedly reducing IN levels thus precluding the formation of IN complexes with viral RNA; (ii) adversely affecting functional IN multimerization and consequently impairing IN binding to viral RNA; and (iii) directly compromising IN-RNA interactions without substantially affecting IN levels or functional …

Curricular Changes Proposed For 2021-2023 Morris Catalog Division Of Science And Mathematics, Curriculum Committee

Curriculum Committee Reports

No abstract provided.

A Review Of Quarantine Period In Relation To Incubation Period Of Sars-Cov-2, Satya Rashmit Durugu, Hammad Tanzeem, Divya Menghani, Zahid Imran, Priya Krishnan

The University of Louisville Journal of Respiratory Infections

Introduction: The period from exposure to a potential pathogen to the manifestation of symptoms, i.e.  the incubation period, is time the virus spends replicating in the host. An estimation of this period and subsequent quarantine of the host can limit potential spread, particularly in asymptomatic carriers. Effective contact tracing, length of self-quarantine, repeat testing, and understanding of disease transmission are all contingent on a true estimation of this incubation period.

Methods: Articles in English published since December 1st, 2019, on Google scholar, PubMed, and Research Gate, along with bulletins from the World Health Organization and the Centers for Disease Control …

Gastrointestinal Sars Cov-2 Infection And The Dynamic Of Its Detection In Stool, Rafik Elbeblawy, Mohammed Abbas, Islam Gadelmoula, Akshitha Kolla, Bettina Sinanova, Jose Bordon

The University of Louisville Journal of Respiratory Infections

Introduction: SARS-CoV-2 has been strongly associated with respiratory illnesses; however the incidence of SARS-CoV-2 infection of the gastrointestinal tract is not fully clear. We examined the frequency of positive stool SARS-CoV-2 reverse transcription-polymerase chain reaction (RT-PCR) in COVID-19 patients, duration of stool viral shedding after the viral clearance of respiratory samples, and the association of SARS-CoV-2 infection with gastrointestinal symptoms.

Methods: We did a search in PubMed and Google Scholar of studies published in the English language before June 30th, 2020. Search queries included: “COVID-19”, “SARS-CoV-2”, and “stool SARS-CoV-2 RT-PCR”. We excluded studies with less than 8 patients from our …

2020-09-21_Michiganoverview_Covidsymptoms, Michigan Department Of Health & Human Services

Michigan COVID-19 Syndromic Surveillance System Data

The Syndromic Surveillance System Data report was obtained from Michigan's COVID-19 dashboard, from under the link "​Coronavirus Symptoms": https://www.michigan.gov/coronavirus. Data was compiled by the Michigan Department of Health and Human Services (MDHHS). The information was updated daily.

Syndromic Surveillance System data is obtained from approximately 183 facilities participating in syndromic surveillance (132 Emergency Departments (ED), 51 Urgent Cares) across the State of Michigan. The reporting is based on individuals who present at EDs and may not be representative of the overall population. The coronavirus-like symptoms query searches visit free-text (chief complaint, triage notes, and clinical impression) for fever or …

The Glycocalyx And Its Role In Vascular Physiology And Vascular Related Diseases, Sheldon Weinbaum, Limary M. Cancel, Bingmei M. Fu, John M. Tarbell

Publications and Research

Purpose—In 2007 the two senior authors wrote a review on the structure and function of the endothelial glycocalyx layer (Weinbaum in Annu Rev Biomed Eng 9:121–167, 2007). Since then there has been an explosion of interest in this hydrated gel-like structure that coats the luminal surface of endothelial cells that line our vasculature due to its important functions in (A) basic vascular physiology and (B) vascular related diseases. This review will highlight the major advances that have occurred since our 2007 paper.

Methods—A literature search mainly focusing on the role of the glycocalyx in the two major areas described above …

Crow's Nest, September 21, 2020, Crow's Nest Staff

Crow's Nest

The September 21, 2020, issue of the Crow's Nest.

Infliximab And The Effect On Immunity To Hepatitis B In Patients With Inflammatory Bowel Disease, Sarybeth Tirado Martinez, Audrey P. Miller, Deana Goldin

International Nursing Research Congress (INRC)

The purpose of this review is to revise and refine the available evidence in support of a clinical guideline for the yearly screening of sero-immunity to hepatitis B as part of ongoing follow-up therapy for patients, ages six to 20 years old, diagnosed with Inflammatory Bowel Disease and on infliximab.

Human Parainfluenza Virus Fusion Complex Glycoproteins Imaged In Action On Authentic Viral Surfaces, Tara Marcink, Tong Wang, Amédée Des Georges, Matteo Porotto, Anne Moscona

Advanced Science Research Center

Infection by human parainfluenza viruses (HPIVs) causes widespread lower respiratory diseases, including croup, bronchiolitis, and pneumonia, and there are no vaccines or effective treatments for these viruses. HPIV3 is a member of the Respirovirus species of the Paramyxoviridae family. These viruses are pleomorphic, enveloped viruses with genomes composed of single-stranded negative-sense RNA. During viral entry, the first step of infection, the viral fusion complex, comprised of the receptor-binding glycoprotein hemagglutininneuraminidase (HN) and the fusion glycoprotein (F), mediates fusion upon receptor binding. The HPIV3 transmembrane protein HN, like the receptor-binding proteins of other related viruses that enter host cells using …

In Vitro Susceptibility Of Treponema Pallidum Subsp Pallidum To Doxycycline, Diane G Edmondson, Gary P Wormser, Steven J Norris

Faculty, Staff and Student Publications

Doxycycline is regarded as an effective therapy for early syphilis, and there is increasing interest in using doxycycline for prophylaxis of this infection. However, the MIC of doxycycline for Treponema pallidum subsp. pallidum has not been reported previously. In this study, an in vitro culture system was utilized to determine that the MIC of doxycycline is 0.06 to 0.10 μg/ml for four strains of T. pallidum subsp. pallidum (Nichols, SS14, UW231B, and UW249B). The Nichols strain cultured in vitro with doxycycline was also tested for infectivity in rabbits, and the minimum bactericidal concentration (MBC) was found to be ≤0.1 μg/ml …

An Evidence-Based Protocol To Improve Hpv Vaccine Initiation Rates At A County Immunization Clinic, Claire Renee Steiner, Brenda L. Cassidy, Jason Dechant, Lauren Brungo

International Nursing Research Congress (INRC)

Human Papillomavirus (HPV) is responsible for 26,900 cancer cases each year in the USA, but not all teenagers are vaccinated against it. This project examines vaccine initiation rates before and after implementation of a multi-modal protocol at a nurse-run immunization clinic. Rates increased with use of same way/same day recommendations.

Bayesian Estimation Of Lassa Virus Epidemiological Parameters: Implications For Spillover Prevention Using Wildlife Vaccination, Scott L. Nuismer, Christopher H. Remien, Andrew J. Basinski, Tanner Varrelman, Nathan Layman, Kyle Rosenke, Brian Bird, Michael Jarvis, Peter Barry, Patrick W. Hanley, Elisabeth Fichet-Calvet

School of Biomedical Sciences

No abstract provided.

Scientific, Methodological And Organizational Bases Of Management Of The Epidemic Process In Case Of Salmonellous Infection In Uzbekistan, Оmon М. Mirtazayev, Nikolay I. Briko, Gulbakhor S. Matnazarova, Nargiza S. Saidkasimova, Botir Y. Toshboev, Nilufar T. Khamzaeva

Central Asian Journal of Pediatrics

In the last decade, the epidemiological characteristics of salmonellosis have changed, in particular, the incidence of human disease has increased, and salmonella infection of farm animals, birds and the environment has increased. The increasing epidemiological role of agricultural birds and industrial poultry products, the relationship between epizootic and epidemic processes require the restructuring of the existing system of epidemiological surveillance of salmonellosis under epizootic and epidemiological supervision. On the basis of the results of scientific research, epizoolic-epidemiological supervision of salmonellosis has been developed, in relation to the conditions of Uzbekistan.

Perinatal Anxiety And Depression During The Covid 19 Pandemic, Helen Xumin Chen, Nancy Selix, Marcianna Nosek

DNP Qualifying Manuscripts

Abstract

The novel coronavirus disease 2019 (COVID-19) outbreak places perinatal women at higher risk of developing anxiety and depression. Uncertainty, fear, and confusion in medical, social, economic, occupational and political aspects of life in the US add to existing stressors that perinatal women experience. To optimize the quality of perinatal care during the pandemic, appropriate mental health interventions must be implemented to prevent and alleviate perinatal anxiety and depression and improve maternal and infant outcomes. Measures include increased screening, non-pharmacologic and/or pharmacologic interventions and the use of telehealth for care delivery.

Keywords: perinatal anxiety, perinatal depression, COVID-19, SARS CoV-2, maternal …

Pursing Balance And Purpose: Multi-University Students’ Perception Of Time Spend Sleeping, Social Media, And Self-Care Activities., Gary Bradley

Faculty Works

Social media can consume vast amounts of time.Therefore, it is postulated that students need to learn self-control for time management. A significant positive correlation exists between high levels of stress and internet addiction. When students learn good study habits and social media time management skills in school it is posited that once they transition to their professional role, they will continue to use those skills throughout their life.

2020-09-20_Michiganoverview_Covidsymptoms, Michigan Department Of Health & Human Services

Michigan COVID-19 Syndromic Surveillance System Data

The Syndromic Surveillance System Data report was obtained from Michigan's COVID-19 dashboard, from under the link "​Coronavirus Symptoms": https://www.michigan.gov/coronavirus. Data was compiled by the Michigan Department of Health and Human Services (MDHHS). The information was updated daily.

Syndromic Surveillance System data is obtained from approximately 183 facilities participating in syndromic surveillance (132 Emergency Departments (ED), 51 Urgent Cares) across the State of Michigan. The reporting is based on individuals who present at EDs and may not be representative of the overall population. The coronavirus-like symptoms query searches visit free-text (chief complaint, triage notes, and clinical impression) for fever or …

New Paradigm Is Needed For Infectious Disease Prevention And Control, Chen Liang

Bulletin of Chinese Academy of Sciences (Chinese Version)

No abstract provided.

Promote Linkage Of "Four Medicals", Effectively Elevate Strategical Importance Of Medical Education—Interview With Academician Chen Guoqiang, Editorial Office Of Bulletin Of Chinese Academy Of Sciences

Bulletin of Chinese Academy of Sciences (Chinese Version)

No abstract provided.

Strategic Thinking On Strengthening Construction Of National Emergency Prevention And Control System Of Tcm For Major Infectious Diseases, Tong Xiaolin, Zhu Xiangdong, Zhao Linhua, Li Qingwei, Lei Ye, Song Bin, Shao Jianzhu, Wang Qiang, Li Xiuyang, Zheng Yujiao, Fan Aihan

Bulletin of Chinese Academy of Sciences (Chinese Version)

COVID-19 epidemic is still raging globally, while China has not only controlled the spread of the epidemic in time, but domestic production and life have gradually recovered. China's epidemic prevention and control work achieved strategic results, and the full participation of Traditional Chinese Medicine (TCM) has become the highlight of the works. However, confronting of sudden major infectious diseases, the emergency reserves and emergency capabilities of TCM are insufficient, especially in the rapid emergency response mechanism, emergency treatment system, professional personnel training, emergency scientific research system and platform construction, and emergency strategic resource reserve. Strengthening the construction of the TCM …