Digital Commons Network^™

Patients With A Left Ventricular Device And Factors Affecting Readmission, Diana Pitcher

Electronic Theses and Dissertations, 2020-2023

Patients with a left ventricular assist device have a high rate of hospital readmissions after their index (placement of left ventricular device) discharge. With these devices becoming more common providers of care must understand why this population is being readmitted in order to promote well-being and keep patients out of the hospital. The purpose of this study was to identify and describe characteristics of the hospital readmission. This research study was a retrospective analysis of aggregate data from 2013-2019 with a sample size n = 32. The summary of data was described with descriptive statistics. The data was grouped and …

Investigations On The Use Of Hyperthermia For Breast Cancer Treatment, Sreekala Suseela

Electronic Theses and Dissertations, 2020-2023

Hyperthermia using electromagnetic energy has been proven to be an effective method in the treatment of cancer. Hyperthermia is a therapeutic procedure in which the temperature in the tumor tissue is raised above 42°C without causing any damage to the surrounding healthy tissue. This method has been shown to increase the effectiveness of radiotherapy and chemotherapy. Radio frequencies, microwave frequencies or focused ultrasound can be used to deliver energy to the tumor tissue to attain higher temperatures in the tumor region for hyperthermia application. In this dissertation the use of a near field focused (NFF) microstrip antenna array for the …

Advanced Econometic Models For Modeling Flows: Application To Shared Economy, Bibhas Dey

Electronic Theses and Dissertations, 2020-2023

Travel and tourism industry is undergoing transformation with the flourishing of online sharing economy marketplaces such as Bike Share services, Uber/Lyft (for taxi services), Eatwith (for community restaurants), and AirBnB (for accommodation). The current research effort contributes to literature on sharing economy service flow analysis by formulating and estiamting econometric approaches for analyzing frequency variables. The sharing economy alternatives investigated include: (a) accommodation service (AirBnB), (b) bikeshare service (Citi bike, NYC) and (c) ride hailing service (UBER/LYFT/Taxi). In the first part of the dissertation, we develop a copula based negative binomial count model framework to count AirBnB listings at census …

Synthesis Of Ruthenium Bipyridine Conjugated Antibiotic For Fluorescence Lifetime Imaging And Spectroscopy Aided Tracking In Citrus, Ryan Parente

Electronic Theses and Dissertations, 2020-2023

Antibiotic treatment of systemic bacterial plant pathogens is an established practice in many crops; however, in citrus it has only recently become available for growers to utilize against Huanglongbing disease. The preliminary efficacy of these treatments is uncertain due to the inability to track their presence in phloem. The need to monitor their movement in planta, especially their presence and translocation in vascular tissue, is a necessary step in clarifying their effectiveness. Previous work has shown the value of Fluorescence Lifetime Imaging (FLIM) in distinguishing between fluorescent probes and plant tissue autofluorescence, which is normally a barrier in photochemical studies …

Monitoring Pathological Gene Expression And Studying Endogenous Epigenetic Architecture By Crispr/Cas9-Based Tool Development Using Alpha-Synuclein As A Model, Levi Adams

Electronic Theses and Dissertations, 2020-2023

Until recently, complete understanding of the endogenous activity of pathologically relevant genes was out of reach and research was confined to in situ work, plasmid-based constructs and artificial model systems. The development and expansion of the CRISPR/Cas9 genome editing technique has enabled us to explore the molecular underpinnings of gene activation using the cell's own endogenous regulatory environment. In this work, we report on the development of a novel tool to monitor the endogenous activity of a causative gene in Parkinson's disease, a-synuclein. We use CRISPR/Cas9 to insert a highly sensitive engineered luciferase at the C-terminal of a-synuclein and assessed …

Mechanical Behavior Assessment Of Ti-6al-4v Alloy Produced By Laser Powder Bed Fusion, Asif Mahmud

Electronic Theses and Dissertations, 2020-2023

The present work correlates quasi-static, tensile mechanical properties of additively manufactured Ti-6Al-4V (Grade 23) alloy to the phase constituents, microstructure and fracture surface characteristics that changed with post-heat treatment of stress relief (670 °C for 5h) and hot isostatic pressing (HIP with 100MPa at 920 °C for 2h). Ti-6Al-4V alloy tensile specimens in both the horizontal (i.e., X and Y) and vertical (Z) directions were produced by laser powder bed fusion (LPBF) technique. Mechanical properties were determined using quasi-static, tensile testing for both the as-stress-relieved (ASR) and HIP specimens. For the ASR and HIP samples built in X, Y and …

Development And Characterization Of A Novel Serum Free Human Ipsc Motoneuron-Primary Human Schwann Cell Model Of Myelination, Aakash Patel

Electronic Theses and Dissertations, 2020-2023

Myelination and node of Ranvier formation play an important role in saltatory conduction of axonal action potentials in the peripheral nervous system (PNS). Degeneration or damage of this myelin can lead to impairment in the conduction of signals by the axons, and cause deficits in sensory and motor function. Currently, animal-based models are the primary method used to study myelination; however, data generated in animal models generally translate poorly to humans, especially as applied to drug discovery. In order to accurately study myelination in humans without having to rely on human testing, an engineered in vitro model of myelination could …

Provider Reported Implementation Of Nutrition-Related Practices In Childcare Centers And Family Childcare Homes In Rural And Urban Nebraska, Dipti Dev, Aileen Garcia, David A. Dzewaltowski, Susan B. Sisson, Lisa Franzen-Castle, Zainab Rida, Natalie A. Williams, Carly Hillburn, Danae Dinkel, Deepa Srivastava, Christina Burger, Emily Hulse, Donnia Behrends, Natasha Frost

Department of Child, Youth, and Family Studies: Faculty Publications

Approximately 15 million children under age 6 are in childcare settings, offering childcare providers an opportunity to influence children’s dietary intake. Childcare settings vary in organizational structure – childcare centers (CCCs) vs. family childcare homes (FCCHs) – and in geographical location – urban vs. rural. Research on the nutrition-related best practices across these childcare settings is scarce. The objective of this study is to compare nutrition-related best practices of CCCs and FCCHs that participate in the Child and Adult Care Food Program (CACFP) in rural and urban Nebraska. Nebraska providers (urban n = 591; rural n = 579) reported implementation …

The Impact Of Responsive Feeding Practice Training On Teacher Feeding Behaviors In Tribal Early Care And Education: The Food Resource Equity And Sustainability For Health (Fresh) Study, Kaysha Sleet, Susan B. Sisson, Dipti A. Dev, Charlotte Love, Mary B. Williams, Leah A. Hoffman, Valarie Blue Bird Jernigan

Department of Child, Youth, and Family Studies: Faculty Publications

Background: Establishing healthy eating habits early affects lifelong dietary intake, which has implications for many health outcomes. With children spending time in early care and education (ECE) programs, teachers establish the daytime meal environment through their feeding practices.

Objective: We aimed to determine the effect of a teacher-focused intervention to increase responsive feeding practices in 2 interventions, 1 focused exclusively on the teacher’s feeding practices and the other focused on both the teacher’s feeding practices and a nutrition classroom curriculum, in ECE teachers in a Native American (NA) community in Oklahoma.

Methods: Nine tribally affiliated ECE programs were …

Does Context Matter? A Multilevel Analysis Of Neighborhood Disadvantage And Children's Sleep Health, Carlyn Graham, Eric N. Reither, Gabriele Ciciurkaite, Dipti Dev, Jamison Fargo

Department of Child, Youth, and Family Studies: Faculty Publications

Objectives: To determine how demographic, socioeconomic, and neighborhood characteristics are associated with bedtimes among US kindergarteners.

Design: Parents reported bedtimes of their children as well as personal, household, and residential characteristics via interviews in the Early Childhood Longitudinal Study-Kindergarten (ECLS-K) Class of 1998-1999. The ECLS-K links individual households to US Census tracts.

Setting: A random selection of 1,280 schools and surrounding communities in the US.

Participants: A random selection of 16,936 kindergarteners and their parents.

Measurements: The 2 outcomes were regular and latest weekday bedtimes of kindergarteners. Through a series of nested multilevel regression models, these outcomes were regressed on …

The Meanings And Ways Of Parental Involvement Among Low-Income Filipinos, Aileen Garcia, Maria Rosario De Guzman

Department of Child, Youth, and Family Studies: Faculty Publications

Parental involvement in children’s education is an integral component of young children’s academic achievement. Although there is clear evidence regarding the benefits of parental involvement, little is known regarding its impacts, manifestations, and conceptualizations in non-Western societies. Given that parenting and child rearing are imbued with cultural meaning in many profound ways (Super & Harkness,1986), this study employed a phenomenological approach and used pakikipagkwentuhan, a data collection procedure drawn from indigenous Filipino Psychology to closely examine how low-income Filipino parents conceptualize parental involvement and its role in their children’s education. Thirty-one parents/caregivers were engaged in conversation and qualitative data …

Emotional Support And Mental Health Among Somali Men In A Rural Midwestern Town, Julie A. Tippens, Gilbert R. Parra, Patrick Habecker, Kimberly Gocchi Carrasco, Arthur R. Andrews Iii, Angela L. Palmer-Wackerly, Virginia Chaidez, Jordan Soliz, Lisa M. Pytlikzillig, Kirk Dombrowski

Department of Child, Youth, and Family Studies: Faculty Publications

Perceived social support has been correlated with refugees’ positive mental health outcomes; yet, little is known about the perceived sources of support after secondary migration to new-destination rural towns. Somali refugee men (n _ 49) residing in a rural Midwest United States community were recruited using respondent-driven sampling to complete a self-administered structured survey in English or Somali using audio computer-assisted self-interview software. Questions assessed perceived sources of support, psychological distress, and happiness. Somali participants reported low utilization of both informal (30.4%) and formal (24.4%) supports when sad, stressed, or worried. Two thirds of participants reported low levels of …

Collaborative Care At A Distance: Student Therapists’ Experiences Of Learning And Delivering Relationally Focused Telemental Health, Paul Springer, Richard Bischoff, Kara Kohel, Nathan C. Taylor, Adam Farero

Department of Child, Youth, and Family Studies: Faculty Publications

There is mounting evidence that telemental health is an effective delivery method for treating a variety of mental, emotional, behavioral, and relational health problems. While many of the therapeutic skills leading to the effectiveness of face-to-face treatments are transferable, the effectiveness of telemental health requires unique skills. The purpose of this phenomeno- logical study was to determine the experience of learning how to use videoconferencing to deliver relationally focused mental health care. Participants included 10 graduates of a COAMFTE-accredited master’s degree program emphasizing training in telemental health. Each student had practicum placements that required videoconferencing to deliver relation- ally based …

Ethics Based Training For Clinicians: Moving Beyond Ethical Decision Making Models, Bobbi J. Miller, Paul R. Springer

Department of Child, Youth, and Family Studies: Faculty Publications

Clinical training in ethical decision making processes has relied heavily on teaching students to apply ethical codes and legal statutes to written scenarios using ethical decision making models. While an excellent academic exercise, this approach tends to remain abstract and does not prepare students for the complexities of making decisions during the process of therapy. Recently, experts in the field have called for reforms in ethical training, believing current models must move beyond cognitive exercises that detach students from the humanity of their clients and themselves. The described pedagogical approach bridges the gap by using a modified Objective Structured Clinical …

Promoting Higher Quality Teacher–Child Relationships: The Insights Intervention In Rural Schools, Kathleen Moritz Rudasill, Ray Reichenberg, Jungwon Eum, Jentry Stoneman Barrett, Yuenjung Joo, Emily Wilson, Martinique Sealy

Department of Child, Youth, and Family Studies: Faculty Publications

Children’s relationships with teachers in kindergarten are crucial for academic and social success. Research shows that teacher–child relationships are predicated, in part, on children’s temperament. The “INSIGHTS into Children’s Temperament” intervention was intended to improve children’s and teachers’ understanding of their and others’ temperament, and has been shown to improve children’s social skills and self-regulation in urban, under-resourced schools. The current study is part of a replication of the effects of INSIGHTS with a sample in rural schools. The purpose was to test the effectiveness of INSIGHTS for promoting positive relationships between teachers and children in kindergarten. Two cohorts of …

Child Sleep And Socioeconomic Context In The Development Of Cognitive Abilities In Early Childhood, Caroline P. Hoyniak, John E. Bates, Angela D. Staples, Kathleen Moritz Rudasill, Dennis Molfese, Victoria J. Molfese

Department of Child, Youth, and Family Studies: Faculty Publications

Despite a robust literature examining the association between sleep problems and cognitive abilities in childhood, little is known about this association in toddlerhood, a period of rapid cognitive development. The present study examined the association between various sleep problems, using actigraphy, and performance on a standardized test of cognitive abilities, longitudinally across three ages (30, 36, and 42 months) in a large sample of toddlers (N = 493). Results revealed a between-subject effect in which the children who had more delayed sleep schedules on average also showed poorer cognitive abilities on average but did not support a within-subjects effect. Results …

Parent Involvement And Its Influence On Children’S Stem Learning: A Review Of The Research, Julie Thomas, Juliana Utley, Soo-Young Hong, Hunkar Korkmaz, Gwen Nugent

Department of Child, Youth, and Family Studies: Faculty Publications

A growing understanding that parents and teachers can effectively collaborate to help children succeed in school has led worldwide policymakers and school leaders to begin deliberate actions to increase parents’ participation in school life. For example, the Chilean Education Minister recently encouraged contracts between parents, schools, and the state to increase parental involvement. The Australian government has formed a Research Alliance for Children and Youth to develop and promote understanding of parent involvement (i.e., what it is, why it matters, how it influences learning) and to build evidence about what works. From a sociological perspective, a school’s organizational boundaries are …

Choosing Quality Early Childhood Curricula, Rachel E. Schachter, Shayne B. Piasta, Laura M. Justice

Department of Child, Youth, and Family Studies: Faculty Publications

This article summarizes a study investigating the curricula and features of those curricula used by 497 early childhood educators across one Midwestern state. Curricula were identified and coded for quality features derived from the research, theory, and policy literatures. Results indicated that most educators utilized Creative Curriculum or High Scope (over 60%); however, these and many other curricula did not include all the key quality features. Importantly, most educators were utilizing curricula with no evidence of effectiveness for supporting children’s outcomes. Furthermore, limitations in the presence of key curricula features may indicate that curricula generally are not adequately supporting early …

An Investigation Into The Curricula (Type And Quality) Used By Early Childhood Educators, Rachel E. Schachter, Shayne B. Piasta, Laura M. Justice

Department of Child, Youth, and Family Studies: Faculty Publications

Most preschool-aged children spend time in Head Start and other center-based care. Thus, early educators’ use of a quality curriculum is essential to maximizing children’s learning. We examined the curricula utilized by educators working in diverse settings with children ages 3 to 5, focusing on key features of quality curriculum identified from the literature. Most educators (75%) reported using formal curricula. Creative Curriculum and HighScope were the most common; 6% of educators reported no curriculum use. There was a lack of consensus regarding what constitutes curriculum with 16% of participants reporting the use of materials generally not considered curriculum (e.g., …

Comparison Of Urban And Rural Physical Activity And Outdoor Play Environments Of Childcare Centers And Family Childcare Homes, Danae Dinkel, Dipti Dev, Yage Guo, Ami Sedani, Emily Hulse, Zainab Rida, Kayla Abel

Department of Child, Youth, and Family Studies: Faculty Publications

The purpose of this study was to examine the physical activity environment in childcare programs across type (childcare centers [CCCs] and family childcare homes [FCCHs]) and geographic location (urban and rural) as assessed by physical activity best practices according to the Go Nutrition and Physical Activity Self-assessment in Child Care. Results showed CCCs compared with FCCHs reported higher achievement of best practices. Further, urban childcare programs (CCCs and FCCHs) reported higher achievement of best practices in comparison to rural childcare programs. There is a need to deliver targeted interventions that promote children’s physical activity in FCCHs and CCCs in rural …

Eastern North Carolina Head Start Teachers’ Personal And Professional Experiences With Healthy Eating And Physical Activity: A Qualitative Exploration, Virginia C. Stage, Lorelei Jones, Jocelyn Bayles, Archana V. Hegde, Dipti Dev, L. Suzanne Goodell

Department of Child, Youth, and Family Studies: Faculty Publications

Objective: Explore the interrelationship between teachers’ personal and professional socio-ecological structures while examining Head Start (HS) teachers’ experiences with (1) trying to eat healthy and engage in physical activity (PA) and (2) promote healthy eating and PA in their classrooms.

Design: In-depth semi-structured interviews were collected from March through June 2017. Researchers designed the data collection and analysis methods using a phenomenological approach. All interviews were recorded using digital audio and transcribed verbatim.

Setting: Seven HS centers in two rural eastern North Carolina counties.

Participants: Teachers (n 15) who had recently participated in a healthy eating and physical activity …

Does Context Matter? A Multilevel Analysis Of Neighborhood Disadvantage And Children's Sleep Health, Carlyn Graham, Eric Reither, Gabriele Ciciurkaite, Dipti Dev, Jamison Fargo

Department of Child, Youth, and Family Studies: Faculty Publications

Objectives: To determine how demographic, socioeconomic, and neighborhood characteristics are associated with bedtimes among US kindergarteners.

Design: Parents reported bedtimes of their children as well as personal, household, and residential characteristics via interviews in the Early Childhood Longitudinal Study-Kindergarten (ECLS-K) Class of 1998–1999. The ECLS-K links individual households to US Census tracts.

Setting: A random selection of 1,280 schools and surrounding communities in the US.

Participants: A random selection of 16,936 kindergarteners and their parents.

Measurements: The 2 outcomes were regular and latest weekday bedtimes of kindergarteners. Through a series of nested multilevel regression models, these outcomes were regressed on …

Feminazis And Social Justice Warriors: Gender And Rhetoric Is Superhero Film Fan Culture, Shelby Miksch

EWU Masters Thesis Collection

No abstract provided.

Multitarget Stool Dna Testing For The Prevention Of Colon Cancer: Outcomes In A Large Integrated Healthcare System, Nimish Vakil, Kristin Ciezki, Nadia Huq, Maharaj Singh

School of Dentistry Faculty Research and Publications

Background and Aims

Multitarget stool DNA (MT-sDNA) testing is used in primary care as a screening test for colon cancer. Test effectiveness and patient compliance were examined in clinical practice.

Methods

We assessed outcomes of MT-sDNA testing in a cohort study conducted in a large integrated healthcare system comprising 15 hospitals and 150 outpatient clinics using advanced electronic data capture (Clarity2 [Epic, Verona, Wisc, USA] and REDCap [Encinitas, Calif, USA]) followed by manual chart review to confirm MT-sDNA test results and to monitor the outcomes of subsequent colonoscopy.

Results

A total of 6835 MT-sDNA tests were performed over 1 year …

Hydrogen Peroxide Preconditioning Promotes Protective Effects Of Umbilical Cord Vein Mesenchymal Stem Cells In Experimental Pulmonary Fibrosis, Tayebeh Mahmoudi, Kamal Abdolmohammadi, Hamed Bashiri, Mehdi Mohammadi, Mohammad Jafar Rezaie, Fardin Fathi, Shohreh Fakhari, Mohammad Ali Rezaee, Ali Jalili, Mohammad Reza Rahmani, Lobat Tayebi

School of Dentistry Faculty Research and Publications

Purpose

Idiopathic pulmonary fibrosis (IPF) is a progressive lung disorder with few available treatments. Mesenchymal stem cell therapy (MSCT), an innovative approach, has high therapeutic potential when used to treat IPF. According to recent data, preconditioning of MSCs can improve their therapeutic effects. Our research focuses on investigating the anti-inflammatory and antifibrotic effects of H₂O₂-preconditioned MSCs (p-MSCs) on mice with bleomycin-induced pulmonary fibrosis (PF).

Methods

Eight-week-old male C57BL/6 mice were induced with PF by intratracheal (IT) instillation of bleomycin (4 U/kg). Human umbilical cord vein-derived MSCs (hUCV-MSCs) were isolated and exposed to a sub-lethal concentration (15 …

Genetic Evidence, Maoa, And State V. Yepez, Nita A. Farahany, Roderick T. Kennedy, Brandon L. Garrett

Faculty Scholarship

No abstract provided.

The Transparency Of Jail Data, William E. Crozier, Brandon L. Garrett, Arvind Krishnamurthy

Faculty Scholarship

Across the country, pretrial policies and practices concerning the use of cash bail are in flux, but it is not readily possible for members of the public to assess whether or how those changes in policy and practice are affecting outcomes. A range of actors affect the jail population, including: law enforcement who make arrest decisions, magistrates and judges who rule at hearings on pretrial conditions and may modify such conditions, prosecutors and defense lawyers who litigate at hearings, pretrial-service providers who assist in evaluation and supervision of persons detained pretrial, and the custodian of the jail who supervises facilities. …

Injustice And The Disappearance Of Discretionary Detention Under Trump: Detaining Low Risk Immigrants Without Bond, Robert Koulish, Kate Evans

Faculty Scholarship

This Report demonstrates that the Immigration and Customs Enforcement (ICE) violates legal requirements to provide immigrants with an individualized custody determination. Trump’s enforcement policies brought a surge of low-risk immigrants into ICE custody. The detention risk tool was supposed to train officers and strongly discourage them from detaining low-risk immigrants who posed no harm to society and were not a flight risk. Data received pursuant to FOIA show the opposite result. ICE has failed to perform the individualized assessment and restrict its use of civil detention to only those whose high levels of dangerousness and risk of flight justify their …

Firearms, Extreme Risk, And Legal Design: "Red Flag" Laws And Due Process, Joseph Blocher, Jacob D. Charles

Faculty Scholarship

The most prominent recent development in gun regulation has been the spread of extreme risk protection order (ERPO) laws—often called “red flag” laws—which permit the denial of firearms to individuals who a judge has determined present an imminent risk of harm to themselves or others. Following a wave of adoptions in the wake of the Parkland murders, such orders are now authorized by law in eighteen states and the District of Columbia, and under consideration in many others. Advocates argue that they provide a tailored, individualized way to deter homicide, suicide, and even mass shootings by providing a tool for …

Sandra Day O’Connor’S "First" Principles: A Constructive Vision For An Angry Nation, Lisa Kern Griffin

Faculty Scholarship

During her 25-year tenure on the Supreme Court, Justice Sandra Day O’Connor cast the decisive votes to resolve the most emotional debates, yet she maintained collegiality among the Justices and retained the public’s high regard. A recent biography by historian and journalist Evan Thomas chronicles her extraordinary personal qualities, remarkable professional journey, and constructive brand of patriotism. This book review essay describes a legacy in three parts: a lived example of how to thrive in the face of challenges, a jurisprudence driven by the courage to make compromises, and a theory about the long game of American democracy. First reintroduces …