Digital Commons Network^™

Constraints On Phytoplankton Abundance And Cyanotoxin Production In The Tidal Freshwater James River, Brittany Ann Moretz

Theses and Dissertations

The tidal freshwater James River exceeds chlorophyll-a (CHL-a) water quality standards and the cyanotoxin microcystin is commonly present. Efforts to control harmful algal blooms in the James have brought about significant reductions in nitrogen and phosphorus inputs, but chlorophyll levels have not changed. In order to better understand the factors constraining harmful algal blooms in this system, we performed three factorial mesocosm experiments that tested how light (ambient, enhanced), mixing (weak mixing, well-mixed), and the availability of dissolved inorganic nitrogen (pre/post NH₄⁺ reductions) influence the abundance of phytoplankton (CHLa, particulate organic carbon [POC]) and cyanotoxin production (microcystin, anatoxin) …

A Comparison Of Computer- And Interviewer-Administered Measures To Identify Heavy/Problem Alcohol And Other Drug Use In Primary Care Patients, David J. Pomm

Theses and Dissertations

Substance use is a leading cause of morbidity and mortality that is under-identified in primary care settings. Screening for substance use in primary care requires an efficient and accurate approach. Exploring methods to collect sensitive and accurate data about substance use and related problems is important to inform research practice and clinical care. Using RCT data comparing computerized and therapist delivered brief intervention for substance use problems, the present study had a unique opportunity to compare computerized anonymous and confidential surveys to a confidential, interviewer-administered assessment in a sample of N = 540 males and females at risk for heavy/problem …

Black Women And Body Image: Implications Of The Racialized Beauty Aesthetic, Rachel L. Boutte

Theses and Dissertations

Black women have the highest prevalence of overweight and obesity relative to any other demographic group in the United States, however current weight management interventions appear least effective for them. Although several hypotheses have been proposed to explain these outcomes, few studies have collected data to evaluate how well they fit the lived experiences of Black women. In particular, the potential roles of body image and body dissatisfaction in the development and maintenance of overweight and obesity in Black women are not well understood. Extant literature largely reports that Black women are inoculated from body dissatisfaction due to cultural factors, …

Design Hub: Activating Community By Design, Ed Williams

Theses and Dissertations

MOTIVATION

At the turn of the century, Robert Putnam (2000, 27) wrote “...a powerful tide bore Americans into ever deeper engagement in the life of their communities, but a few decades ago that tide reversed and we were overtaken by a treacherous rip current.” Putnam is describing a loss of “social capital” throughout American society. Research suggests that many of our contemporary issues are the result of a decline in “social capital,” or “community.”

This pervasive lack of community is thought to be detrimental to “educational performance, safe neighborhoods, equitable tax collection, democratic responsiveness, everyday honesty, and even our health …

Exosomes As Systemic Mediators Of Nanotube Induced Neurotoxicity, Christopher G. Canal

Theses and Dissertations

Extra-pulmonary effects of nanoparticle inhalation have been well documented; however, mechanisms for conveying peripheral bioactivity remain elusive. Recent studies point to indirect molecular mediators shed into the circulation. Protein and lipid alternatives to cytokines or chemokines have been proposed, yet the diversity among responses suggests a broader assemblage of factors. Recently we have proposed proteolytic fragment peptides as an additional source of bioactivity, which interestingly were significantly associated with exosomal proteins after enrichment analysis. Here we tested whether modeled exposure to multi-walled carbon nanotubes (MWCNT) could alter the composition and bioactivity of circulating exosomes. Male C57BL/6 mice were exposed by …

Adverse Childhood Experiences In Children Presenting To Integrated Pediatric Primary Care, Irene A. Jacobs

Theses and Dissertations

The prevalence of adverse childhood experiences (ACEs) has created a significant public health concern in the United States. A vast body of literature examining adult populations has displayed a dose-response association between cumulative ACEs and chronic illnesses (Chapman et al., 2004; Felitti et al., 1998). ACEs research conducted with children and adolescents has indicated higher ACE scores associated with learning and behavioral problems (Burke et al., 2011), health risk behaviors (Garrido et al., 2018), and mental health challenges (Mackner et al., 1997). However, ACEs research and subsequent interventions have largely relied upon retrospective data retrieved from adults (Felitti et al., …

Competing Models Of Exposure To Community Violence Among Urban Youth: Dimensional Versus Person-Centered Approaches, Sarah K. Pittman

Theses and Dissertations

Exposure to community violence is prevalent among urban youth residing in neighborhoods with high rates of crime and violence. Although there is strong evidence suggesting that community violence exposure is associated with negative consequences on youth development, there are inconsistencies in theories and evidence regarding the nature of these associations. Methodological limitations of dimensional approaches to conceptualizing exposure, including the assumption that adolescents are similar in their frequency and patterns of exposure, likely contribute to the inconsistencies in findings of associations. Recently, person-centered methods have been used to elucidate associations between community violence exposure and consequences on adolescent development. However, …

Effects Of A Self-Advocacy Intervention On The Abilities Of College Students With Intellectual And Developmental Disabilities To Request Academic Accommodations, Katherine R. Brendli

Theses and Dissertations

Students with intellectual and developmental disabilities (IDD) are pursuing college at higher rates than ever before. However, many of these students experience barriers to success in college and need to self-advocate for their needs, such as requesting academic accommodations. This study examined the effects of a virtually delivered self-advocacy intervention package on the abilities of college students with IDD to request their academic accommodations. This is the first study to virtually implement a modified version of the Self-Advocacy and Conflict Resolution strategy with college students with IDD. Using a single-subject multiple-probe across participants design, this study was implemented with three …

Investigation Of Molecular Mechanisms Of Liver Preservation Injury: A Complication Preceding Organ Transplantation, Ria C. Fyffe-Freil

Theses and Dissertations

Of the over 108,000 American awaiting a life-saving organ transplant today, over 12,000 (11%) of those need a new liver (OPTN, 2020). Last year, only 35% of patients on the waiting list for an organ were transplanted. Improving the quality of marginal organs by preventing or reversing preservation injury could vastly increase the number of transplants performed. Washout of circulating blood during liver procurement with cold University of Wisconsin solution flushes out any endogenous pro-survival signaling molecules. We investigated lysophospholipid (LPL) surface receptors (G-protein coupled receptors for lysophosphatidic acid (LPA) and sphingosine- 1-phosphate (S1P)) and their role in protecting hepatocytes …

Development And Validation Of Predictive Risk And Multiple Criteria Decision Analysis Models To Evaluate Cardiovascular Outcomes Among Cancer Patients, Purva N. Parab

Theses and Dissertations

Objective: The objectives of our study were to characterize the study population with cancer and cardiovascular diseases (CVD) both as compared to those without and to build a predictive model using machine learning (ML) algorithms that can predict the risk of CVD in cancer patients. In addition, our objective was also to evaluate characteristics associated with cardiotoxic adverse events of breast cancer therapies and develop a multiple criteria decision analysis (MCDA) model to conduct benefit-risk assessment of breast cancer therapy regimens. Methods: We used Medical Expenditure Panel Survey (MEPS) and FDA Adverse Events Reporting System (FAERS) 2005-2015 files along with …

An Online Mindfulness Training For Improved Eudaimonic Well-Being And Sleep Outcomes In Caregivers: A Preliminary Study, Tarah L. Raldiris

Theses and Dissertations

As the United States population continues to age, the number of older adults with dementia is projected to rise. Much of the care for those with dementia is provided by unpaid, informal caregivers who are typically family members. Unfortunately, these informal caregivers express significantly higher levels of negative psychological and physical health outcomes compared to non-caregivers. One potential pathway for improving caregiver outcomes may be through increased mindfulness. Using a two-week, online-based mindfulness training program and a structurally equivalent cognitive reappraisal training program, study aims were to: 1.) investigate the acceptability and feasibility of using an online intervention format for …

Characterizing Patterns Of Cannabis Use And Related Health Effects Among Young Adults Using Ecological Momentary Assessment, Alyssa Rudy

Theses and Dissertations

Introduction: Rapid changes in cannabis use policy and prevalence, particularly among young adults, and the lack of information regarding cannabis harms warrant investigation regarding the daily use patterns of cannabis users. Little is known regarding how variability in cannabis use frequency and administration method use patterns may be associated with differential acute cannabis-related health effects (i.e., subjective intoxication and respiratory symptoms). The purpose of the study was to characterize daily and weekly cannabis use patterns and associated cannabis-related intoxication and respiratory symptoms and test the interactions of cannabis use frequency and cannabis administration method use on cannabis-related intoxication and respiratory …

Differential Identification Of Hyperacusis And Misophonia: Implications Of Discrete Decreased Sound Tolerance (Dst) Condition Subtypes, Rachel E. Wallace

Theses and Dissertations

Hyperacusis and misophonia are two conditions of decreased sound tolerance (DST) studied in the psychological literature due to their association with psychological symptoms and mechanisms. DSTs are differentiated from normal sound sensitivity due to the reported impairment and distress individuals experience. Researchers suggest that DSTs are differentiated by types of sounds and emotional reactions elicited, such that hyperacusis is a fear and pain response to ordinary environmental sounds perceived as uncomfortably loud, and misophonia is an anger and disgust response to human-made sounds, but these distinctions, and associated characteristics, have not been empirically demonstrated. Undergraduate students (N = 1572) …

The Pseudomonas Aeruginosa Interactome: Insights Into Srna-Mediated Regulatory Networks, Christine M. Van Duyn

Theses and Dissertations

Pseudomonas aeruginosa is a Gram-negative bacterium found in various environmental niches including soil, water, hospital environments, and within a broad range of hosts. It is well known for its metabolic versatility and intrinsic and acquired resistance to a variety of antimicrobial agents. Moreover, this bacterium has a remarkable ability to adapt and survive in suboptimal environments by altering its transcriptional profile in response to nutrient deprivation, changes in temperature and pH, osmotic stress, the presence of reactive oxygen species (ROS), and exposure to antibiotics and host defenses. P. aeruginosa colonizes individuals with compromised immune systems and severe burn injuries and …

Interpersonal Competency Configurations And The School Adjustment Of Early Adolescents With Disabilities: A Person-Centered Approach, Brittany I. Sterrett

Theses and Dissertations

The transition to middle school is a critical time in adolescence. The more complex school environment provides opportunities for growth and challenges for students with disabilities. Although special education strives to provide individualized supports to students with disabilities through data-based decision-making, the tools used to understand and meet the needs of these students are often unresponsive to the dynamic nature of development and student adjustment as they age. Grounded in developmental science, this study sought to create a data collection framework through a person-centered approach to inform the individualization process. Specifically, this study: 1) explored a decision process that allows …

Development Of A Screening Assay For Type Iii Secretion System Inhibitors And High Throughput Screening Campaign Of Inhibitors Of Prp Of Staphylococcus Aureus, Heather A. Pendergrass

Theses and Dissertations

Antibiotics inhibit the growth or survival of bacteria by targeting their essential functions.¹ Due to weaknesses in traditional antibiotics and the increasing prevalence of antibiotic resistance genes, virulence factors are being targeted for therapeutic treatment of bacterial infection.² We have developed an assay to quantify and observe type III secretion system (T3SS) activity. The type III secretion system (T3SS) is a virulence factor present in some Gram-negative pathogens including enteropathogenic and enterohemorrhagic E. coli (EPEC and EHEC, respectively),³ and others.^4–9 The T3SS between EPEC and EHEC are highly conserved and share over 90% sequence identity with …

A Longitudinal Test Of Mexican Teen Mothers’ Cultural Characteristics And Children’S Language Skills Via Mothers’ Language, Arlenis A. Santana

Theses and Dissertations

The current study includes 204 Mexican teen mothers and their children from a larger study who were interviewed when children were 3 years old (Wave 4; W4), 4 years old (W5), and 5 years old (W6). The current study is guided by the integrative model of developmental competencies (García Coll et al., 1996), which suggests that parents’ adaptive cultural characteristics and exchanges with their children inform children’s developmental competencies. Thus, the current study examined whether teen mothers’ adaptive cultural characteristics (i.e., familism values, language competency pressures, and involvement in Mexican culture and U.S. mainstream culture) at W4 informed mothers’ Spanish …

Dating Violence Victimization And Posttraumatic Stress Outcomes Among Urban Adolescents: The Moderating And Mediating Role Of Positive Outlook, Carine Leslie

Theses and Dissertations

Adolescent dating violence occurs far too frequently in early adolescence and is related to adverse mental health outcomes, including posttraumatic stress symptoms. One focus within this literature has been to determine and better understand how protective processes may function in influencing relations between risk factors and dating violence victimization. A protective factor that has not been explored in the dating literature is positive outlook. The current short-term longitudinal study investigated whether dating violence victimization at Time 1 predicted posttraumatic stress symptoms at Time 2 among African American middle school students and examine whether positive outlook moderated or mediated this relation. …

Comorbidity In Context: Identifying Patterns Of Depressive And Anxiety Symptoms In African American Early Adolescents, Kathryn Behrhorst

Theses and Dissertations

Depression and anxiety during adolescence includes symptoms of irritability, sleeplessness, feelings of guilt or worthlessness, worry, avoidance, and/or restlessness. Anxiety and depressive symptoms are often comorbid and are associated with impairments across academic, social, and emotional areas of functioning. No studies to date have examined patterns of depressive and anxiety symptoms together for African American adolescents using person-centered analyses. The current study examined patterns of symptoms and domains of anxiety and depression during early adolescence using latent profile analyses (LPA). A sample of 196 African American early adolescents in grades six through eight (M_age = 12.6; 50% female) were …

Kinematic And Coordination Variability In Runners With And Without Patellofemoral Pain, Jessica Mutchler, Klarie Macias, Barry Munkasy, Samuel J. Wilson, John C. Garner Iii, Li Li

Health Sciences & Kinesiology: Faculty Publications

Background: Patellofemoral pain (PFP) is a common overuse injury that has been suggested to cause abnormal gait kinematics and variability in runners with PFP. Conflicting results have been presented as to the variability of joint kinematics and joint coordination. Objective: The purpose of this study was to examine the variability of lower extremity kinematics and joint coordination in the presence of PFP and exertion. Methods: Six female runners with PFP and matched controls (CON) ran at a self-selected pace on an instrumented treadmill until exertion or pain criteria was met. Sixteen anatomical retroreflective markers and seven tracking clusters were placed …

Breaking The Silence On Father-Daughter Sexual Abuse Of Adolescent Girls: A Case Law Study, Janine Benedet, Isabel Grant

All Faculty Publications

Adolescent girls are targeted for sexual violence at a rate higher than females at any other life stage. Girls most often face sexual violence at the hands of men that they know and trust within their own families, yet this type of abuse has largely evaded scrutiny from the #MeToo movement. In this article, the authors seek to revitalize the discussion of sexual abuse against adolescent girls by their fathers. The article is part of a larger study that examined all Canadian judicial decisions involving sexual offences against girls between the ages of twelve and seventeen inclusive over a three-year …

Ecg Biometric Authentication: A Comparative Analysis, Mohit Ingale, Renato Cordeiro, Siddartha Thentu, Younghee Park, Nima Karimian

Faculty Research, Scholarly, and Creative Activity

Robust authentication and identification methods become an indispensable urgent task to protect the integrity of the devices and the sensitive data. Passwords have provided access control and authentication, but have shown their inherent vulnerabilities. The speed and convenience factor are what makes biometrics the ideal authentication solution as they could have a low probability of circumvention. To overcome the limitations of the traditional biometric systems, electrocardiogram (ECG) has received the most attention from the biometrics community due to the highly individualized nature of the ECG signals and the fact that they are ubiquitous and difficult to counterfeit. However, one of …

Making Implementation Last: Understanding The Sustainability Of An Evidence-Based Treatment, Carrie Beth Jackson

Graduate Theses, Dissertations, and Problem Reports (ETD)

Although advances have been made in facilitating the implementation of evidence-based treatments, little is known about the most effective way to sustain their use over long periods of time. Prior systematic reviews and research have suggested that organizational characteristics and training methods may be strategies that support sustainability, yet this has remained relatively unstudied in the field of behavioral health. The current study examined the sustainability of Parent-Child Interaction Therapy following a statewide implementation trial testing three training methods. Participants included 100 clinicians and 50 administrators from 50 organizations across Pennsylvania. Multi-level path analysis was utilized to examine the role …

Community Development Financial Institutions (Cdfis): An Analysis Within The Political And Economic Context Of Neoliberalism, Tracie Victoria Wynand

Cal Poly Humboldt theses and projects

This thesis explores Community Development Financial Institutions (CDFIs) business models by examining the organizational structures, procedural operations, services, and geography. It aims to understand its overall behavior as a financial institution providing low-income communities financial services and ultimately the role it plays within the neoliberal context. The research identifies that CDFIs ultimately hold a mission that promotes economic prosperity from within the neoliberal project by expanding free-market capitalist beliefs and practices when servicing low-income communities. Additionally, the findings suggest that CDFIs take on the role of the neoliberal state by operating in tandem with the Nonprofit Industrial Complex (NPIC), which …

Efficacy Of Forest Restoration Treatments Across A 40-Year Chronosequence At Redwood National Park, Kevin Soland

Cal Poly Humboldt theses and projects

Following 20^th century logging, much of the natural coast redwood (Sequoia sempervirens) range consists of dense second-growth stands with slow tree growth and low biodiversity. There is a landscape-scale effort in much of coastal northern California to increase tree growth rates and ecosystem biodiversity via thinning treatments, thereby hopefully accelerating the development of old-growth forest characteristics. Redwood National Park (RNP) has been experimenting with thinning in these forest types since the 1970s. Given the interesting history of logging and restoration in RNP and the future plans for widespread thinning in this region, my thesis examined the effects …

Changing Seasons Of Resistance: Impacts Of Settler Colonialism And Climate Change In Indigenous Worlds, Elizabeth Jackson

Cal Poly Humboldt theses and projects

This paper looks at the relationship between neoliberal capitalism, genocide, the biopolitics of settler colonialism and the impacts of climate change on the cultures and traditional lifeways of Indigenous communities. It also explores Indigenous modes and methods of adaptation and resilience. Climate Change is almost certainly the most urgent social problem in the history of human life on planet Earth. Many Indigenous people are more vulnerable to the effects of climate change due to marginalization and their commitment to land-based practices. Using in depth interviews with Indigenous Peoples, primarily from the Pacific Northwest, and the analysis of existing literature, this …

Coho Salmon (Oncorhynchus Kisutch) Dispersal And Life History Variations Among Humboldt Bay Watersheds, Madison J. Halloran

Cal Poly Humboldt theses and projects

The decline of Coho Salmon (Oncorhynchus kisutch) in California is the result of various anthropogenic effects across the landscape, affecting all stages of their anadromous life history. Monitoring a subset of the remaining populations is essential to evaluate the success of management actions and develop new restoration projects. Defining the appropriate spatial scale for this monitoring and restoration depends on the frequency and extent of dispersal of individuals across watershed boundaries. Coho Salmon life-cycle monitoring projects in California estimate the abundance of juveniles and adults over time in selected focal watersheds. If individuals frequently enter or leave the …

Assessing Convergent Validity Of The Qabf And Tbh Fa Intake Form With Results Of A Functional Analysis, Melissa Cisneros

Cal Poly Humboldt theses and projects

The current study looked to compare and analyze the convergent validity of the Questions About Behavioral Function (QABF) with Trumpet Behavioral Health’s current form, the Functional Assessment Intake Form. Both forms were compared with results gathered from a functional analysis conducted on individuals with identified challenging behaviors (e.g. body dropping and self- injurious behaviors). A multi-element design was used to conduct a functional analysis, and identified functions from the indirect assessments were compared to the results found in the functional analysis. Results indicated that there was no correspondence between the indirect assessments used with the results from the functional analysis. …

From Screen To Summit: An Investigation Of Claims About Social Media Use For Outdoor Recreation Purposes, Theodora M. Doyon

Cal Poly Humboldt theses and projects

Recent increases in visitation to public lands in the U.S. are often attributed to a rise in social media sharing of outdoor spaces, and particularly to the use of geotagging and hashtagging for location sharing. There are conflicting views on the influence of social media on visitation to public lands, including negative perceptions of social media users, and positive perceptions of social media’s potential to spread information to underrepresented and underserved communities. Due to the growing interest in social media use and its effects on outdoor spaces, it is important to understand how social media use correlates with recreational behavior …

Phylogenetic And Population Genetic Analysis Of The Humboldt's Flying Squirrel Using High-Throughput Sequencing Data, Stella Chi Yuan

Cal Poly Humboldt theses and projects

The intraspecific genetic variation and diversity within the Humboldt’s flying squirrel (Glaucomys oregonensis) has not yet been characterized despite its elevation to full species in 2017. The San Bernardino flying squirrel (G. o. californicus) is thought to be the southernmost population of G. oregonensis and is restricted to the San Bernardino and San Jacinto Mountains in California, but recent surveys indicate they have been extirpated from the latter locality. In order to provide baseline genetic data across the geographic range of G. oregonensis, I had the following objectives: 1) investigate the intraspecific molecular variation in …