Digital Commons Network^™

Daily Eastern News: November 17, 2020, Eastern Illinois University

November

No abstract provided.

Metabolic Network Analysis Reveals Altered Bile Acid Synthesis And Metabolism In Alzheimer's Disease., Priyanka Baloni, Cory C Funk, Jingwen Yan, James T Yurkovich, Alexandra Kueider-Paisley, Kwangsik Nho, Almut Heinken, Wei Jia, Siamak Mahmoudiandehkordi, Gregory Louie, Andrew J Saykin, Matthias Arnold, Gabi Kastenmüller, William J Griffiths, Ines Thiele, Alzheimer’S Disease Metabolomics Consortium, Rima Kaddurah-Daouk, Nathan D Price

Articles, Abstracts, and Reports

Increasing evidence suggests Alzheimer's disease (AD) pathophysiology is influenced by primary and secondary bile acids, the end product of cholesterol metabolism. We analyze 2,114 post-mortem brain transcriptomes and identify genes in the alternative bile acid synthesis pathway to be expressed in the brain. A targeted metabolomic analysis of primary and secondary bile acids measured from post-mortem brain samples of 111 individuals supports these results. Our metabolic network analysis suggests that taurine transport, bile acid synthesis, and cholesterol metabolism differ in AD and cognitively normal individuals. We also identify putative transcription factors regulating metabolic genes and influencing altered metabolism in AD. …

Structure Of The Receptor Binding Domain Of Envp(B)1, An Endogenous Retroviral Envelope Protein Expressed In Human Tissues, Kevin R Mccarthy, Joseph L Timpona, Simon Jenni, Louis-Marie Bloyet, Vesna Brusic, Welkin E Johnson, Sean P J Whelan, Lindsey R Robinson-Mccarthy

Open Access Publications

EnvP(b)1 is an endogenous retroviral envelope gene found in human and other primate genomes. We report EnvP(b)1 sequences in primate genomes consistent with an integration event between 40 and 71 million years ago. Using a highly specific polyclonal antiserum raised against the putative receptor binding domain (RBD) of human EnvP(b)1, we detected expression in human placenta, ovaries, and thymus. We found that EnvP(b)1 is proteolytically processed, and using cell-cell fusion assays in multiple primate cell lines, we demonstrated that extant EnvP(b)1 proteins from a variety of primate genomes are fusogenic. This work supports the idea that EnvP(b)1 is under purifying …

Multi-Agent Simulation Model For Covid-19 Virus Prevention And Control, Lihu Pan, Shipeng Qin, Xiaowen Li, Feiping Lu, Fenyu Yang

Journal of System Simulation

Abstract: The prevention and control of the novel coronavirus (COVID-19) is the priority work to maintain the public health security of the world nowadays. The COVID-19 prevention and control model using multi-agent modeling and simulation technology is proposed. The model can simulate the different dynamic development trend of the epidemic under different prevention and control measures. Taking Taiyuan as an example, according to the researched COVID-19 transmission rules, the prevention and control simulation of COVID-19 has been achieved under the designing rule of the interactive infection process and status transition process between various resident agents. Multi-scenario simulation experiments are realized …

An Ulk1-Independent Mechanism Of Atg9a Regulation In Basal Autophagy, Ashari Rashmi Kannangara

Theses and Dissertations

Macroautophagy (hereafter referred to as autophagy) is the bulk degradation and recycling of cytoplasmic materials by forming a double membrane vesicle called the autophagosome. Autophagosome formation is regulated by the coordinated action of a set of proteins. ATG9A is the only multispanning transmembrane protein that plays an essential role in autophagosome formation, yet its function is largely elusive. Previous studies have shown that the C-terminus of ATG9A plays an important role in regulating its trafficking and proper function in autophagy. In line with that idea, we previously identified an AMPK- and ULK1- mediated phosphorylation on the C terminus of ATG9A …

Pengembangan Sistem Informasi Monitoring Dokumen Rekam Medis Rawat Inap Di Rsup Fatmawati Tahun 2020, Grahyta Dhamayanti, Martya Rahmaniati

Jurnal Biostatistik, Kependudukan, dan Informatika Kesehatan

Di era digital saat ini rumah sakit dituntut untuk memanfaatkan teknologi informasi yang bertujuan untuk meningkatkan pelayanan kesehatan. Teknologi informasi juga digunakan untuk memperbaiki mutu rekam medis rawat inap yang sering menghasilkan informasi yang tidak efektif bagi rumah sakit. Informasi yang tidak efektif sering disebabkan oleh adanya rekam medis rawat inap yang tidak lengkap dan terlambat dikembalikan. Di RSUP Fatmawati Jakarta terdapat peningkatan prosentase keterlambatan pengembalian dan ketidaklengkapan dokumen rekam medis rawat inap. Penelitian ini bertujuan untuk mengetahui dan mengidentifikasi alur, kebutuhan sistem informasi yang akan dikembangkan, serta merancang sistem informasi monitoring dokumen rekam medis rawat inap di RSUP Fatmawati. …

Experiences Among Adults And Adolescents During The Covid-19 Pandemic From Four Locations Across Kenya—Study Description, Timothy Abuya, Karen Austrian, Adan Isaac, Beth Kangwana, Faith Mbushi, Eva Muluve, Daniel Mwanga, Thoai Ngo, Mercy Nzioki, Rhoune Ochako, Jessie Pinchoff, Ben Tidwell, John Wanyungu, Corinne White

Poverty, Gender, and Youth

To control the spread of coronavirus, the COVID-19 National Emergency Response Committee (NERC) in Kenya, chaired by the Ministry of Health (MOH), has implemented prevention and mitigation measures. To inform the Government of Kenya’s shorter- and longer-term response strategies, the Population Council COVID-19 study team utilizes rapid phone-based surveys to collect information on knowledge, attitudes, practices and needs among a longitudinal cohort of heads of household sampled from existing prospective cohort studies. The first was carried out across five Nairobi urban informal settlements; the baseline survey (n=2,009) was conducted March 30–31 with subsequent follow-up surveys conducted April 13–14 (n=1,764), May …

Lindenwood Digest, November 17, 2020, Lindenwood University

Lindenwood Digest

The Lindenwood Digest has been a digital employee newsletter since 2009.

Correcting Inappropriate Prescribing Of Direct Oral Anticoagulants: A Population Health Approach, Taylor Dawson, Deborah Decamillo, Xiaowen Kong, Brian Shensky, Scott Kaatz, Gregory D. Krol, Mona Ali, Brian Haymart, James B. Froehlich, Geoffrey D. Barnes

Hospital Medicine Articles

No abstract provided.

Library Publishing Curriculum Impact Module: Assessment Measures And Strategies (Unit 3), Instructor's Guide, John W. Warren

Library Publishing Curriculum

We have previously discussed methods and tools for strategic planning and crafting effective goals. How do we know if we are making progress towards these goals? How can we determine if our publications and our work is having the impact we want? This unit introduces assessment methods, tools, and metrics that help us measure the impact of individual publications and publishing programs. We will look at the connection between strategic planning and assessment, and practice applying assessment methods to real-world scenarios. In the first half of the unit, we discuss evaluating individual publications, examining the advantages and disadvantages of common …

Library Publishing Curriculum Impact Module: Strategies For Enhancing Discovery And Accessibility (Unit 4), Instructor's Guide, John W. Warren

Library Publishing Curriculum

This unit focuses on the interrelated topics of discovery and accessibility, or how you enable readers to find and use your publications. In the first half of the unit, we will cover best practices in metadata management, common metadata standards and unique identifiers, journal indexing, and search engine optimization. In the second half, we will briefly discuss best practices in accessibility for the web, ebooks, and PDFs, legal and ethical concerns, and universal design.

Gastrointestinal Parasites In The Neotropical Otter (Lontra Longicaudis Annectens) In Central Mexico, Erika Y. Badillo Flores, Marcos G. Torres Tobón, C. Gustavo Aguilar Cabrera, O. Eric Ramírez-Bravo, Eva Romero Callejas

Western North American Naturalist

We analyzed 47 scats of neotropical otter (Lontra longicaudis annectens), collected along the Necaxa River in Central Mexico, using the Willis flotation technique with a 48% saturated saline solution. Along with plant material, we found the endoparasites Oxyuris equi, Ascaris sp., and Strongylus equinus, among others. Our results indicate that otters in the Necaxa River have a parasite load that needs further analysis, particularly because 2 of the parasite species are associated with human activity.


Analizamos 47 excretas de nutria neotropical (Lontra longicaudis annectens), colectadas a lo largo del Río Necaxa en el Centro …

Compounds For The Treatment Of Neurodegenerative Diseases, Jianfeng Cai, Chuanhai Cao

USF Patents

Disclosed herein are compounds for the treatment of neurodegenerative diseases and compositions comprising the same.

Georgia Southern Announces Men’S Basketball Non-Conference Schedule, Ticket Procedure For 2020-21, Georgia Southern University

Athletics: News & Publications

• Georgia Southern Announces Men’s Basketball Non-Conference Schedule, Ticket Procedure for 2020-21

Dysbiotic Lesional Microbiome With Filaggrin Missense Variants Associate With Atopic Dermatitis In India, Shankha Nath, Naina Kumari, Debabrata Bandyopadhyay, Neloy Sinha, Partha P. Majumder, Rupak Mitra, Souvik Mukherjee

Journal Articles

Background: Atopic Dermatitis (AD) has been associated with the loss of function (LoF) mutations in Filaggrin (FLG) gene and increase in relative abundance of specific microbes in the lesional skin, predominantly in Caucasians. Our study aims to determine, in Indian AD patients, (a) the prevalence of FLG LoF and missense mutations, and (b) the nature and extent of dysbiosis and altered microbial pathways with and without mutations in FLG. AD patients (n = 34) and healthy controls (n = 54) were recruited from India in this study and shotgun sequencing was carried out in a subset of samples with adequate …

For Our Sakes: An Incarnational And Systemic Approach To The Challenge Of Poverty, Alan Parker

Faculty Works

How do Christians face the challenge of poverty? This paper proposes a grace-based approach to poverty. By recognizing our poverty and how God has shown grace to us, we are inspired to care for the poverty of others. The problem of the poor, which includes us, is not material poverty but broken relationships. Solving poverty requires that one enter into the world of the poor person and to see the richness that they have, even in their material poverty. The entire system of broken relationships must be repaired and the goal must be the restoration of shalom. We will therefore …

Expanded Covid-19 Testing Available Before Thanksgiving, Staff Report

University of Mississippi News

No abstract provided.

The Political Dynamic Of The Separation Of The Islamic Church And State, Maya Drayton, Rachel Burton, Caroline Donnelly, Brianna Wolfe, Erika Cambron

Content presented at the Roesch Social Sciences Symposium

In this project, we researched the relationship between Islam and the state. We conducted our research by using the University of Dayton databases to find different journals and articles analyzing our topic. We found that the relationship is constantly evolving and depends on where you are located. We also found that Islam has not always been properly investigated and is not as widely understood as it could be.

Gender Roles In Buddhism, Simone Schuller, Deja Tart, Rebekah Beamer, Kathleen Sebastian

Content presented at the Roesch Social Sciences Symposium

No abstract provided.

2020 Program: Raymond A. Roesch, S.M., Social Sciences Symposium, University Of Dayton

Roesch Social Sciences Symposium Programs and Other Materials

No abstract provided.

Citizenship, Locality And Territory, R Yarwood

School of Geography, Earth and Environmental Sciences

No abstract provided.

Review Of Public Health Ethics: Global Cases, Practice, And Context, Nancy Nadeau

Open Educational Resources - Reviews

No abstract provided.

Covid-19 Pandemic: Financial Stability Impact And Policy Responses, Financial Stability Board (Fsb)

Documents

No abstract provided.

Holistic Review Of The March Market Turmoil, Financial Stability Board (Fsb)

Documents

No abstract provided.

2020.11.17 - Finance, Buildings And Grounds Committee Meeting Minutes, Northeastern Illinois University Board Of Trustees

Board of Trustees - 2020

Meeting materials for the NEIU Finance, Buildings and Grounds Committee

Social Work/Public Library Partnerships: Patron Needs Addressed By Msw Students, Beth Wahler Ph.D., Mary Provence Msw, Lcsw, Sarah C. Johnson Mlis, Lmsw

Publications and Research

Dozens of public libraries in the United States partner with social work, including via practicum placements, to address patrons’ psychosocial needs. This presentation examines and compares staff and patron perceptions of patrons’ needs with actual usage of social work practicum student services by patrons within a large urban library branch.

Covid-19 Reduced Outpatient Visits By Up To 70% In The Us, Pinka Chatterji, Yue Li

Population Health Research Brief Series

The COVID-19 pandemic has created new challenges for healthcare providers. Outpatient visits dropped by up to 70% relative to the same weeks in prior years.

Corticotropin-Releasing Factor Infusion In The Bed Nucleus Of The Stria Terminalis Of Lactating Mice Alters Maternal Care And Induces Behavioural Phenotypes In Offspring, Kerstin Camile Creutzberg, Érika Kestering-Ferreira, Thiago Wendt Viola, Luis Eduardo Wearick-Silva, Rodrigo Orso, Bernardo Aguzzoli Heberle, Lucas Albrechet-Souza, Rosa Maria Martins De Almeida, Rodrigo Grassi-Oliveira

School of Medicine Faculty Publications

The peripartum period is accompanied by numerous physiological and behavioural adaptations organised by the maternal brain. These changes are essential for adequate expression of maternal behaviour, thereby ensuring proper development of the offspring. The corticotropin-releasing factor (CRF) plays a key role in a variety of behaviours accompanying stress, anxiety, and depression. There is also evidence that CRF contributes to maladaptations during the peripartum period. We investigated the effects of CRF in the bed nucleus of the stria terminalis (BNST) of lactating mice during maternal care and analysed locomotor activity and anxiety-like behaviour in the offspring. The BNST has been implicated …

Program Review Report, November 17, 2020, Program Review Committee

Program Review Committee

No abstract provided.

2020 November 17, Faculty Senate Minutes, State University Of New York At Cortland

Minutes

Faculty Senate Minutes No. 6, November 17, 2020