Digital Commons Network^™

Sustained Cellular Immune Dysregulation In Individuals Recovering From Covid-19, Jeff Hansen

Browse All News

No abstract provided.

An Assessment Of Knowledge, Attitude, And Practice Of The Kuantan Community On The Effects Of Monosaccharides On Cancer, Muhammad Alif Mazlan, Muhammad Kamil Che Hasan, Afzan Mat Yusof, Muhammad Lokman Md Isa

Makara Journal of Health Research

Background: Cancer knowledge, attitude, and practice (KAP) levels of communities are essential to be assessed to enhance cancer educational programs. This study aimed to determine the KAP level of the Kuantan community on the effects of monosaccharides on cancer. The association between the sociodemographic data and KAP level of the community has also been evaluated.

Methods: A cross-sectional survey was performed among residents living in the Kuantan community. Only 303 of 380 responses were included in the data analysis using the chi-square test.

Results: The knowledge and practice levels were moderate, whereas the attitude was at a …

2020-12-29_Michigandaily_Covidmap, Michigan Department Of Health & Human Services

Daily Michigan COVID-19 Update

The "WHERE WE STAND WITH COVID-19" map was obtained from Michigan's main COVID-19 page: https://www.michigan.gov/coronavirus. Data was compiled by the Michigan Department of Health and Human Services (MDHHS). The information was updated daily at 3p.m., Monday - Saturday.

The State of Michigan is working around the clock to test and treat COVID-19 patients. Below is the most recent data healthcare experts across the state have compiled.

The image contained a map, indicating total cases by county, and also provides statistics on Total Confirmed Cases, Total COVID-19 Deaths, Daily Confirmed Cases, and Daily COVID-19 Deaths. There …

Taking Profound Offence Seriously: Freedom Of Speech V. Human Dignity, Raphael Cohen-Almagor

Journal of Hate Studies

This study discusses the issue of offence to sensibilities as possible grounds for limiting freedom of expression. This issue is constantly brought to the public agenda, as for example, in the limitation imposed in Israel on the playing of Richard Wagner’s music by Israeli orchestras. The proposed thesis is as follows: The Offence to Sensibilities Argument will take precedence over free expression only in cases where profound and direct damage is inflicted upon the sensibilities of individuals or a target group, undermining their dignity, especially when the speaker’s intentions are to offend the target individual/group under circumstances in which the …

Uab Earns Women's Choice Award "Best Hospital" Designation For Six Areas, Alicia Rohan

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No abstract provided.

New York State's Congressional Delegation May Lose Two Members, Jeffrey M. Wice

Redistricting Resources

According to a new report released on December 22, 2020 by Election Data Services, Inc. (EDS), New York State could lose up to two congressional districts after the official state population totals are announced in January. This article explores this possibility through 2020 Census data estimates.

Red Panda: A Novel Method For Detecting Variants In Single-Cell Rna Sequencing, Adam Cornish, Shrabasti Roychoudhury, Krishna Sarma, Suravi Pramanik, Kishor Bhakat, A T. Dudley, Nitish K. Mishra, Chittibabu Guda

Journal Articles: Genetics, Cell Biology & Anatomy

BACKGROUND: Single-cell sequencing enables us to better understand genetic diseases, such as cancer or autoimmune disorders, which are often affected by changes in rare cells. Currently, no existing software is aimed at identifying single nucleotide variations or micro (1-50 bp) insertions and deletions in single-cell RNA sequencing (scRNA-seq) data. Generating high-quality variant data is vital to the study of the aforementioned diseases, among others.

RESULTS: In this study, we report the design and implementation of Red Panda, a novel method to accurately identify variants in scRNA-seq data. Variants were called on scRNA-seq data from human articular chondrocytes, mouse embryonic fibroblasts …

Covid-19 Newsletter (Vol. 52), Center For Disaster Medicine, New York Medical College

COVID-19 Newsletter

No abstract provided.

Emerging From The Deep: Complexity, Emergent Pedagogy And Deep Learning, Sue L. T. Mcgregor

Northeast Journal of Complex Systems (NEJCS)

As indicated in the title – emerging from the deep – this paper proposes that an ability to face and deal with complexity can emerge from deep learning that is facilitated by pedagogies designed to ensure this outcome, especially an emergent pedagogy that instills deep education. Educators would view the classroom as a complex adaptive system (CAS) capable of self-organizing and operating at the edge of chaos where order emerges, just not predictably. Self-directed students would experience a learning environment that is appreciative of nonequilibrium, unpredictability, shifting and emerging patterns and co-evolution. Teachers would be coaches, activators and facilitators. Students …

When Working Out Makes You Sick To Your Stomach: What To Know About Exercise-Induced Nausea, Anne R. Crecelius

Health and Sport Science Faculty Publications

You’re doing it! You’re working out, reaping all those benefits of exercise that have been drilled into your head.

So you’re pedaling your heart out or running like you’re escaping a zombie horde. You’re feeling accomplished, on cloud nine, until … your stomach starts to churn. You may even feel dizzy. Your feelings of accomplishment have turned to agony as you deal with a bout of nausea.

Exercise-induced nausea is quite common, as are exercise-induced gastrointestinal (GI) problems in general, affecting perhaps up to 90% of endurance athletes.

So why does this happen and, more important, how can you prevent …

Detectability Of Circulating Micrornas In Microrna Extracts With Low Purity And Yield Using Quantitative Real-Time Polymerase Chain Reaction: Supporting Evidence, Azmir Ahmad, Mohd. Arifin Kaderi, Afidalina Tumian, Vijaya Mohan Sivanesan, Kahairi Abdullah, Wan Ishlah Leman, Irfan Mohamad, Wan Mohd. Nazri Wan Zainon, Muhammad Izani Mohd. Shiyuti, Kamariah Mohamed Awang, Luqman Rosla, Mark Paul, Sharifah Nor Ezura Syed Yussof, Rosdi Ramli

Makara Journal of Health Research

Background: Circulating microRNAs (miRNAs) are a group of noncoding RNAs with promising potential as minimal invasive biomarkers for noncommunicable diseases. However, challenges exist in the preparation of these miRNAs from peripheral blood samples for quantification purposes. The low quality of miRNA extracts presents an obstacle. Acknowledging the superior performance of quantitative real-time polymerase chain reaction (qPCR) as gold standard for gene expression analysis, we conducted this study to observe the capabilities of qPCR using the Taqman® protocol in amplifying circulating miRNAs from miRNA extracts with low purity and yield.

Methods: miRNAs were extracted from thirty-six plasma samples that …

Sports Under Quarantine: A Case Study Of Major League Baseball In 2020, Kari L.J. Goold, Reynafe N. Aniga, Peter B. Gray

Anthropology Faculty Research

© 2020 by the authors. Licensee MDPI, Basel, Switzerland. This case study entailed a Twitter content analysis to address the pandemic-delayed start to Major League Baseball (MLB) in the shortened 2020 season. This case study helps address the overarching objective to investigate how the sports world, especially fans, responded to MLB played during the 2020 COVID-19 pandemic. The methods investigated the common themes and determined who used predetermined Twitter hashtags. We recorded how many times external links, photos, emojis, and the 30 MLB teams were mentioned in the 779 tweets obtained during 39 days of data retrieval. Results showed that …

Mandating Covid-19 Vaccines, Lawrence O. Gostin, Daniel A. Salmon, Heidi J. Larson

Georgetown Law Faculty Publications and Other Works

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines hold promise to control the pandemic, and help restore normal social and economic life. The Food and Drug Administration (FDA) has granted emergency use authorization (EUA) for 2 mRNA vaccines and will likely issue full biologics licenses in the coming months. Anticipating vaccine scarcity, the Advisory Committee on Immunization Practice (ACIP) published guidance on vaccine priorities.

Data show 95% efficacy for vaccines granted an EUA, but even highly effective vaccines cannot curb the pandemic without high population coverage and maintenance of other mitigation strategies. Recent data from 1,676 adults surveyed November 30-December …

Noninvasive Vagus Nerve Stimulation And Morphine Transiently Inhibit Trigeminal Pain Signaling In A Chronic Headache Model, Lauren E. Cornelison, Jordan L. Hawkins, Sara E. Woodman, Paul L. Durham

College of Natural and Applied Sciences

Introduction: Chronic headache conditions are characterized by persistent sensitization of the trigeminal system, which involves dysfunction of descending pain modulation. We previously reported that noninvasive vagus nerve stimulation (nVNS) inhibits trigeminal nociception in models of episodic migraine through a mechanism involving enhanced serotonergic and GABAergic descending pain signaling. Objectives: The analgesic effectiveness of nVNS and morphine were investigated in an animal model of chronic headache mediated by the combination of the 3 migraine risk factors of neck muscle tension, paradoxical sleep deprivation, and pungent odors. Methods: Sprague-Dawley rats were injected with complete Freund's adjuvant in the trapezius and sleep deprived …

“In The University But Not Of The University”: Examining Institutionalized Counterspaces Through A Staff Perspective, Omar A. Ramirez

Master's Theses

Using a qualitative case study, this thesis examines a university counterspace that serves Students of Color through the perspective of the staff who work in that space. The case study aimed to explore four areas of investigation: the interviewees’ knowledge and perceptions of 1) the history of their counterspace; 2) the purpose of their counterspace; 3) the benefits of their counterspace; and 4) challenges of their counterspace. The counterspace was a program within a large, 4-year, public, R-1 research university. Five staff from the counterspace were interviewed. A thematic analysis of the data suggests that students were an essential part …

Recovery Of Hippocampal-Dependent Learning Despite Blunting Reactive Adult Neurogenesis After Alcohol Dependence, Chelsea G. Nickell, K. Ryan Thompson, James R. Pauly, Kimberly Nixon

Pharmaceutical Sciences Faculty Publications

Background:

The excessive alcohol drinking that occurs in alcohol use disorder (AUD) causes neurodegeneration in regions such as the hippocampus, though recovery may occur after a period of abstinence. Mechanisms of recovery are not clear, though reactive neurogenesis has been observed in the hippocampal dentate gyrus following alcohol dependence and correlates to recovery of granule cell number.

Objective:

We investigated the role of neurons born during reactive neurogenesis in the recovery of hippocampal learning behavior after 4-day binge alcohol exposure, a model of an AUD. We hypothesized that reducing reactive neurogenesis would impair functional recovery.

Methods:

Adult male rats were …

Medical Marijuana And Opioids (Memo) Study: Protocol Of A Longitudinal Cohort Study To Examine If Medical Cannabis Reduces Opioid Use Among Adults With Chronic Pain, Chinazo O. Cunningham, Joanna L. Starrels, Chenshu Zhang, Marcus A. Bachhuber, Nancy L. Sohler, Frances R. Levin, Haruka Minami, Deepika E. Slawek, Julia H. Arnsten

School of Medicine Faculty Publications

Introduction In the USA, opioid analgesic use and overdoses have increased dramatically. One rapidly expanding strategy to manage chronic pain in the context of this epidemic is medical cannabis. Cannabis has analgesic effects, but it also has potential adverse effects. Further, its impact on opioid analgesic use is not well studied. Managing pain in people living with HIV is particularly challenging, given the high prevalence of opioid analgesic and cannabis use. This study's overarching goal is to understand how medical cannabis use affects opioid analgesic use, with attention to Δ9-tetrahydrocannabinol and cannabidiol content, HIV outcomes and adverse events. Methods and …

Experiential Statistics: A Case Study In Favor Of Using Project-Based Learning To Advance Preliminary Statistics Content Knowledge In The Algebra I And Geometry Classroom, Trey Michael Earle

LSU Doctoral Dissertations

Preparing secondary students for college entrance requirements and the expectations of the job market, a market which is actively seeking the employees who are most qualified to take on jobs that require data analysis skills, is becoming increasingly important. Federal, state, and local education administrators and personnel must rewrite many of the general education curricula to incorporate data organization, collection, manipulation, application, and analysis in order to better prepare students for the expectations of college entrance and an ever-changing employment market. From a purely pedagogical standpoint, while traditional educational structure has been commonplace for decades in the United States, projects …

Online Learning In Vocational Education Of China During Covid-19: Achievements, Challenges, And Future Developments, Xibin Han, Qian Zhou, Wanruo Shi, Shuyuan Yang

Journal of Educational Technology Development and Exchange (JETDE)

COVID-19 has challenged education systems globally. Traditional teaching and learning activities of more than 1,300 vocational colleges and nearly 11,000 vocational high schools in China have had to be paused and transformed into an online mode. A study had been conducted to trace the unprecedented change which would provide reflections on policies and practical experience worthy of reference for the follow-up development of online vocational education in China and other countries in the world. The study used two methods to collect data: (1) delivering questionnaires to 767 schools, 17009 teachers, 270,732 students, and (2) gathering 110 institute cases from 21 …

Exploring The Relationship Between Anger, Aggression, And Perpetrator Substance Use In The Commission Of Sexual Offenses, Dominique Rivera

Student Theses

This study examined the potential association between perpetrator substance use, anger, and aggressive behavior in the commission of sexual crimes. The sample included 246 adult males convicted of rape (n = 54) or child molestation (n = 192). Descriptive statistics revealed that 64.6% of the individuals in this sample (n = 159) were intoxicated at the time of the offense. Results showed that perpetrators who used substances at the time of the offense were more likely to exhibit aggressive behavior toward the victim (e.g., weapon use, verbal abuse) than those who did not. Offenders with higher pervasive anger scores were …

Changes In University Club Athletes’ And Non-Athlete Students’ Stress And Perceived Gains Across A Semester, Eric A. Martin, Alana Unfried, Steven Kim, George K. Beckham

Kinesiology Faculty Publications and Presentations

To examine the relationship between club rugby participation, collegiate experiences, and perceived gains, 25 rugby players and 25 non-athlete students completed the Student-Athlete Experiences Inventory-Revised, Student-Athlete Gains Inventory, and Perceived Stress Scale at the start and end of a semester. A RM-ANOVA and partial-η² effect sizes determined if group and time differences were present. We selected variables associated with the post-scores for practical and liberal arts gains with the lasso method. Rugby players engaged in more diverse social interactions (partial-η² = 0.091) and were more actively involved on campus (partial-η² = 0.0914) than non-athlete students, but paradoxically …

Modulation Of Aub-Tdrd Interactions Elucidates Pirna Amplification And Germplasm Formation., Nicholas Vrettos, Manolis Maragkakis, Panagiotis Alexiou, Paraskevi Sgourdou, Fadia Ibrahim, Daniel Palmieri, Yohei Kirino, Phd, Zissimos Mourelatos

Computational Medicine Center Faculty Papers

Aub guided by piRNAs ensures genome integrity by cleaving retrotransposons, and genome propagation by trapping mRNAs to form the germplasm that instructs germ cell formation. Arginines at the N-terminus of Aub (Aub-NTRs) interact with Tudor and other Tudor domain-containing proteins (TDRDs). Aub-TDRD interactions suppress active retrotransposons via piRNA amplification and form germplasm via generation of Aub-Tudor ribonucleoproteins. Here, we show that Aub-NTRs are dispensable for primary piRNA biogenesis but essential for piRNA amplification and that their symmetric dimethylation is required for germplasm formation and germ cell specification but largely redundant for piRNA amplification.

Informing The Conversation - Covering The Care, Bridget Drake

UNH Today Archive

No abstract provided.

State V. Jolley Appellant's Brief Dckt. 48139

Not Reported

No abstract provided.

Childhood Trauma And Post-Trauma Environment Affect Fear Memory And Alcohol Use Differently In Male And Female Mice, Gavin Vaughan, Katherine Kompanijec, Shreyya Malik, Allison R. Bechard

Psychology

Background: Childhood trauma is associated with the development of adult mental health and substance use disorders, with females generally being more at risk. Alcohol is commonly used for coping with trauma, and alcohol use disorder (AUD) affects ~14.4 million adult Americans annually. Research investigating sex differences in the environmental modification of anxiety and alcohol use following childhood trauma will extend our understanding of the etiology of AUD. Here, we sought to model the interacting effects of a single-episode late childhood trauma with post-trauma environment on adult alcohol use using male and female mice.

Methods: C57Bl6/J mice (d22) exposed to predator …

Filial Piety Expectations And Loneliness Among Older People In Kuantan, Pahang, Aniawanis Makhtar, Nor Hafizah Samsudin

Makara Journal of Health Research

Background: Filial piety plays a vital role in combating loneliness among older people. Older adults have a high tendency to feel lonely when affection toward and from their children decreases. This study aimed to determine the association between filial piety expectations and loneliness among older people in Kuantan, Pahang.

Methods: A cross-sectional study was conducted on 198 older people in Kuantan, Pahang. Filial piety expectation and loneliness were measured by the Filial Piety Expectation Scale and UCLA (University of California, Los Angeles) Loneliness Scale questionnaire. The data were analyzed by using SPSS version 22.0.

Results: The results …

Factors Influencing Health Service Utilization Among The Elderly In Insein Township, Yangon Region, Sandar Min Min Hlaing, Naw Clara, Aye Nanda Han

Makara Journal of Health Research

Background: With the increasing needs of the aging population and the increasing prevalence of non-communicable diseases, assessment of the equity and accessibility of health care among the elderly has become important.

Methods: A cross-sectional descriptive study was conducted from December 2018 to December 2019 among 225 elderly to describe the factors influencing health service utilization. Multistage sampling was applied, and structured questionnaire was used to interview the elderly. Chi-squared test and multiple logistic regression were performed in data analysis.

Results: The average age of the respondents was 71.7 ± 8.17 years old, and 68.4% of the respondents …

The Role Of Parents In Providing Sexuality Education To Their Children, Nur Azira Fideyah Binti Abdullah, Siti Mariam Muda, Norhasmah Mohd Zain, Siti Hazariah Abdul Hamid

Makara Journal of Health Research

Background: Parents have an important role in delivering sexuality education to their children. However, Asian parents are reluctant to discuss sexual matters with their children owing to the sensitivity of the topic and their lack of sexual health knowledge. This study aimed to examine Malaysian parents’ knowledge, attitudes, and practices in providing sexuality education to their children.

Methods: A self-administered questionnaire was used to conduct this cross-sectional study featuring 200 Malaysian parents. Descriptive and univariate analyses were performed using Statistical Package for Social Study (SPSS) version 23.0.

Results: Among the majority (79.5%) of the parents having good …

Knowledge, Attitudes, And Practices Of Adolescents Regarding Sexuality And Reproductive Issues In The Cordillera Administrative Region Of The Philippines, Eddieson Pasay-An, Judith Odanee G. Magwilang, Petelyne P. Pangket

Makara Journal of Health Research

Background: This study investigates the knowledge, attitudes, and practices (KAP) concerning reproductive health (RH) and sexuality among in- and out-of-school adolescents in the Cordillera Administrative Region (CAR), Philippines.

Methods: Using a quantitative, cross-sectional approach, this study examined 739 in- and out-of-school adolescents who were recruited through snowball and simple random sampling.

Results: Statistically significant differences were noted in the knowledge, attitudes, and practices regarding sexuality based on age. Age was associated with knowledge, attitudes, and practices concerning RH. Educational attainment toward sexuality also caused statistically significant changes in knowledge, attitudes, and practices. The KAP regarding sexuality and …

Dental Caries Among 12-Year-Old Children After Discontinuation Of Water Fluoridation In Pahang, Malaysia, Faizah Abdul Karim, Zamros Yuzadi Mohd Yusof, Nor Azlida Mohd Nor

Makara Journal of Health Research

Background: Water fluoridation (WF) has been a national caries prevention program in Malaysia since 1972. However, between July 2012 and December 2013, WF was discontinued in Pahang. This study aimed to compare caries prevalence and mean caries experience among Malaysian children in WF and WF-ceased areas and determine its associated risk factors.

Methods: This cross-sectional study was conducted among 12-year-old schoolchildren in two Malaysian states: Pahang (WF-ceased) and Perak (WF-continued). Dental caries was examined using ICDAS criteria, and a questionnaire was used to collect relevant data. Associations between independent variables and dental caries were analyzed by simple logistic …