Digital Commons Network^™

Influence Of Single Nucleotide Polymorphisms On Rifampin Pharmacokinetics In Tuberculosis Patients, Levin Thomas, Sonal Sekhar Miraj, Mallayasamy Surulivelrajan, Muralidhar Varma

Open Access archive

Rifampin (RF) is metabolized in the liver into an active metabolite 25-desacetylrifampin and excreted almost equally via biliary and renal routes. Various influx and efflux transporters influence RF disposition during hepatic uptake and biliary excretion. Evidence has also shown that Vitamin D deficiency (VDD) and Vitamin D receptor (VDR) polymorphisms are associated with tuberculosis (TB). Hence, genetic polymorphisms of metabolizing enzymes, drug transporters and/or their transcriptional regulators and VDR and its pathway regulators may affect the pharmacokinetics of RF. In this narrative review, we aim to identify literature that has explored the influence of single nucleotide polymorphisms (SNPs) of genes …

Vulnerability Of Small Forest Patches To Fire In The Paraiba Do Sul River Valley, Southeast Brazil: Implications For Restoration Of The Atlantic Forest Biome, Betina J. Guedes, Klecia G. Massi, Cody Evers, Max Nielsen-Pincus

Environmental Science and Management Faculty Publications and Presentations

The Atlantic Forest biome, a biodiversity hotspot historically threatened by deforestation and human disturbance, has recently seen a net gain in native forest cover due to changes in land use, enactment of new laws, and substantial investment in restoration. Like many South American and global ecosystems, the Atlantic Forest biome has also experienced an increase in area burned by wildfire largely due to human ignitions, which threatens these gains. Our objective was to understand the vulnerability of protected areas and small patches of neotropical forest to fire in the Paraíba do Sul River Valley, Brazil, a region within the Atlantic …

Matching The Speed Of Technology With The Speed Of Local Government: Developing Codes And Policies Related To The Possible Impacts Of New Mobility On Cities, Marc Schlossberg, Heather Brinton

TREC Final Reports

Advances in transportation technology such as the advent of scooter and bikeshare systems (micromobility), ridehailing, and autonomous vehicles (AV’s) are beginning to have profound effects not only on how we live, move, and spend our time in cities, but also on urban form and development itself. These new technologies are changing the systems of transport, the layout of cities, and the places we spend our time. In turn, these changes will likely have additional and profound effects on land use, street design, parking, housing, equity, municipal finance, and fundamental issues related to urban density, sprawl, vitality and the economic viability …

Addressing Reentry Experiences In California During Covid-19, Emily R. Cook

Social Sciences

I will first provide a literature review surrounding the topic of reentry and recidivism. Next, I will describe the projects that I completed related to reentry and reintegration in California including: participating in various parts of an educational reentry simulation, analyzing student responses to participation in this simulation, organizing a care package drive to assist those recently released, and creating a resource website compiling updates on the COVID- 19 crisis inside of the California incarceration system. I conclude by reflecting on my senior project experience.

Civil Rights Ecosystems, Joanna C. Schwartz

Michigan Law Review

The Philadelphia and Houston Police Departments are similarly sized, but over a recent two-year period, ten times more civil rights suits were filed against Philadelphia and its officers than were filed against Houston and its officers. Plaintiffs in cases brought against Philadelphia and its officers were awarded one hundred times more in settlements and judgments. What accounts for these differences? Although the frequency and severity of misconduct and injury may play some role, I contend that the volume and outcome of civil rights litigation against any given jurisdiction should be understood as a product of what I call its civil …

Growth Velocity In Children With Environmental Enteric Dysfunction Is Associated With Specific Bacterial And Viral Taxa Of The Gastrointestinal Tract In Malawian Children, Chandni Desai, Scott A. Handley, Rachel Rodgers, Cynthia Rodriguez, Maria I. Ordiz, Mark J. Manary, Lori R. Holtz

Open Access Publications

Environmental enteric dysfunction (EED) is characterized by diffuse villous atrophy of the small bowel. EED is strongly associated with stunting, a major public health problem linked to increased childhood morbidity and mortality. EED and subsequent stunting of linear growth are surmised to have microbial origins. To interrogate this relationship, we defined the comprehensive virome (eukaryotic virus and bacteriophage) and bacterial microbiome of a longitudinal cohort of rural Malawian children with extensive metadata and intestinal permeability testing at each time point. We found thirty bacterial taxa differentially associated with linear growth. We detected many eukaryotic viruses. Neither the total number of …

Executive Summary Of The Early-Onset Breast Cancer Evidence Review Conference., David Chelmow, Mark D Pearlman, Amy Young, Laura Bozzuto, Sandra Dayaratna, Myrlene Jeudy, Mallory E Kremer, Dana Marie Scott, Julia Sage OʼHara

Department of Obstetrics and Gynecology Faculty Papers

The Centers for Disease Control and Prevention launched the Bring Your Brave campaign to increase knowledge about early-onset breast cancer, defined as breast cancer in women aged 18-45 years. The American College of Obstetricians and Gynecologists convened a panel of experts in breast disease from the Society for Academic Specialists in General Obstetrics and Gynecology to review relevant literature, validated tools, best practices, and practice guidelines as a first step toward developing educational materials for women's health care providers about early-onset breast cancer. Panel members conducted structured literature reviews, which were then reviewed by other panel members and discussed at …

June 2020 News Releases, University Of Montana--Missoula. Office Of University Relations

University of Montana News Releases, 1928, 1956-present

No abstract provided.

The Impact Of Social Media On Mental Health: A Mixed-Methods Research Of Service Providers’ Awareness, Sarah Nichole Koehler, Bobbie Rose Parrell

Electronic Theses, Projects, and Dissertations

The relationship between heavy use of social media and an increase in mental health disorders has long been established. However, there is a gap in the literature regarding mental health practitioners/providers’ responses to this issue. This mixed-methods research embraced two theoretical perspectives—Ecological Model and Generalist Intervention Model—toward determining the extent to which mental health practitioners/providers assess for the impact of heightened use of social media on mental health. Qualitative and quantitative data were collected from 95 mental health practitioners (N = 95) via Qualtrics.

Non-parametric tests and descriptive statistics showed that prior training, agency’s values, and credentials impact mental health …

Striking The Balance: Us Army Force Posture In Europe, 2028—A Study Sponsored By The Office Of The Secretary Of The Army, J. P. Clark Col, C. Pfaff

Books, Monographs & Collaborative Studies

Within the context of Europe, the US Army must develop a force posture that best navigates the tensions between deterring or defeating armed conflict at an acceptable cost, successfully competing below armed conflict, and maintaining global responsiveness and institutional flexibility through the global operating model and dynamic force employment. While Russia’s economy, and consequently military capability will likely shrink over the next 10 years, which can make them more dangerous as the Kremlin continues to try to punch above its weight. The ideal force posture needs to accomplish a range of on-going and contingency missions and also be adaptive enough …

User-Rated Comfort And Preference Of Separated Bike Lane Intersection Designs, Christopher Monsere, Nathan Mcneil, Rebecca Sanders

Civil and Environmental Engineering Faculty Publications and Presentations

Improved bicycle infrastructure has become increasingly common in the United States as cities seek to attract new riders, including the demographic who do not feel comfortable riding with motor vehicle traffic. A key tool in designing low-stress networks is the use of separated or protected bicycle lanes, and intersections are the critical links. This paper presents an analysis of the perceived level of comfort of current and potential bicyclists from 277 survey respondents who rated 26 first-person video clips of a bicyclist riding through mixing zones, lateral shifts, bend-in, bend-out, and protected intersection designs. A total of 7,166 ratings were …

Conceptual Design Of A South Pole Carrier Pigeon Uav, Kendrick M. Dlima

Master's Theses

Currently, the South Pole has a large data problem. It is estimated that 1.2 TB of data is being produced every day, but less than 500 GB of that data is being uploaded via aging satellites to researchers in other parts of the world. This requires those at the South Pole to analyze the data and carefully select the parts to send, possibly missing out on vital scientific information. The South Pole Carrier Pigeon will look to bridge this data gap.

The Carrier Pigeon will be a small unmanned aerial vehicle that will carry a 30 TB solid-state hard drive …

Land Of Abundance: A History Of Settler Colonialism In Southern California, Benjamin Shultz

Electronic Theses, Projects, and Dissertations

The historical narrative produced by settler colonialism has significantly impacted relationships among individuals, groups, and institutions. This thesis focuses on the enduring narrative of settler colonialism and its connection to American Civilization. It is this process and system of American Civilization (established and reified through institutions and cultural norms) that perpetuates the oppressive impact of settler colonialism on various groups who have resided in Southern California for generations before the settlers arrived. This thesis will also demonstrate that the results of settler colonialism at the turn of the 20^th century in Southern California had massive socioeconomic consequences in the …

Eating Disorder Treatment: What Former Patients Attribute To Their Personal Recovery, Wendy Ingram

Electronic Theses, Projects, and Dissertations

The purpose of this study was to explore the personal experience of people who have an eating disorder with a specific focus on what they attributed to their recovery. Eating disorders are a mental illness that affect one in 20 people. Thus, this prevalence coupled with a lack of significant research about eating disorders in the field of social work uncovered the need for this study.

Qualitative interviews were completed with five female students from a university in California. Each transcript was coded using conventional content analysis to uncover themes and subthemes, which included barriers to recovery, the need to …

Geospatial Applications To Mitigate Concentrated Animal Feeding Operations From Impacting Surface Water Resources, Elias Rex

Electronic Theses, Projects, and Dissertations

Concentrated Animal Feeding Operations (CAFOs) offer the ability to meet the rising demands of population growth by housing large amounts of livestock on relatively small areas of land, using medication to accelerate their maturation, and reusing waste products as fertilizers. However, there is a growing abundance of literature related to land use configurations and their effects on water resources, many of which highlight agriculture as a primary contributor of nutrients and fecal bacteria found in surrounding water resources. The purpose of this study is to advance the current knowledge surrounding CAFO land-use and its effect on tributaries within the Cape …

Porous Religious Economies And The Problem Of Regulating Religious Marketplaces, Orlando Woods

Research Collection School of Social Sciences

This paper reframes the theory of religious economy by developing an understandingof the effects of transnational religious influence on religious marketplaces. It highlightsthe need to rethink the role of regulation in shaping the ways in which religiousmarketplaces operate. By reinterpreting regulation as the ability of the state to controlthe extent to which religious groups are able to access resources, it argues thattransnational religious networks can enable access to extraneous resources, which, inturn, can enable religious groups to subvert the regulatory prescriptions of the state.Transnational religious influences therefore highlight the porosity of religiouseconomies, and the problem of regulating religious marketplaces. Qualitative …

The Response Of International Law To The Challenges To Human Security, Waseem Ahmad Qureshi

California Western International Law Journal

No abstract provided.

Jun2020, Robert Kelly

Robert Kelly Manuscripts

No abstract provided.

First & Second Cycles Final Report For: Educational And Workforce Development Through Creation Of Programs In Transportation To Generate Future Careers For Our Students In Navajo Nation Region, Gholam Ehteshami

Publications

Navajo Technical University (NTU) in New Mexico, has made a partnership with the Tran-SET regional center at Louisiana State University, LSU. We have provided learning and training the Native American students in transportation-related Industries to some of STEM students at NTU through these partnerships opportunities. The program was designed and supported by Native American students from high school to STEM undergraduate students. The program was implemented accordingly with four main components: (1). Selected eligible and interested Native American student to paid summer internships to the field and facilities of transportations industries and participate in research summer at LSU. (2). Directed …

Is The Identity Development Process Intersectional?: The Story Of 15 Gay White Male Chicagoans, Jacob Stone

College of Liberal Arts & Social Sciences Theses and Dissertations

Research on multiple identities highlights intersectionality as key to understanding overlapping forms of oppression and power within a single individual. This structural understanding of the individual, however, misses how individuals understand this multiplicity and the process taken for them to develop it. This study combined my experience as a gay white man with 14 life history interview of gay white men between the ages of 21 and 42 living in Chicago. Gay identity development primarily occurs through the dissipation of barriers to self-acceptance, while white identity development takes constant conscious thought and action to build up understanding. The inverse nature …

Neutrosophic Causal Modeling For Analyzing The Diffusion Of The Institutional Culture: The Case Uniandes, Rafael Carlos Hernández Infante, María Elena Infante Miranda, Francisco René Rivadeneira Enríquez, César Josué Galeano Páez

Neutrosophic Sets and Systems

The dissemination of culture is an activity assumed by teaching institutions. Knowing the cultural elements that characterize each nation allows to preserve the cultural heritage. However, quantifying this result represents a complex task to perform. This research proposes a solution to the problem posed with the design of a multicriteria method for the evaluation of cultural diffusion. The method uses neutrosophical numbers to model uncertainty. The proposal introduced the results in UNIANDES, Ibarra and it was found that it has a high rate of cultural diffusion.

Improved Marching Cubes Algorithmand Its Three-Dimensional Meteorological Simulation, Shuoben Bi, Lu Yuan, Xiaowen Zeng, Mingyue Lu, Yonghua Zhang

Journal of System Simulation

Abstract: Methodof obtaining intersection points of isosurface and vowex by linear interpolation in original Marching Cubes algorithm has been replaced by the method of trisecting element boundaries. The problem of linear interpolation not suitable for meteorological data simulation is therefore solved and the number of triangular facets in isosurfacemapping is effectively reduced. While reducing redundancy and improving mapping speed, the quality of isosurface mapping is further improved. The improved Marching Cubes algorithm is applied to the simulation of meteorological model data, i.e., the isosurface of WRF data, and good results are obtained in both the speed of image rendering and …

Dyslexia Beyond The Word: An Ecological Study Of Specific Reading Disorder, Benjamin T. Carter

Theses and Dissertations

This dissertation discusses the effects of dyslexia on reading behavior and cognition. It does so by first outlining the overall incidence of dyslexia, providing current definitions, giving a history of scientific inquiry and discussing relevant contemporary research. Thirteen different analyses are then discussed (ten a priori and three post-hoc). Individuals with dyslexia were found to have increased fixation duration, first run dwell time, total dwell time, and refixation probability. The dyslexia group was also highly sensitive to lexical predictability. Within the reading network, the BOLD response was depressed in dyslexia during reading in the following regions: the left medial and …

Attraction To Both Genders And The Link To Depression Mediated By The Big Five And Permissiveness In Relationships, Jolene Elizabeth Wyman

Masters Theses

The outcome of depression has been well established for sexual minorities. This can be seen in particular within the research regarding those who are attracted to both genders (ABG). The lifestyle choice of nonmonogamous or open relationships is commonly found in ABG relationships. These behaviors demonstrate the concept of permissiveness in relationships. The negative effect of the nonmonogamous lifestyle yields mixed results of either no developed psychopathologies and more personal satisfaction or in developed psychopathologies such as depression. Conscientiousness is often negatively correlated to ABG, permissive behavior in relationships, and depression. The current hypothesis is that conscientiousness and permissiveness in …

The Total Solar Eclipse Of 2017: Meteorological Observations From A Statewide Mesonet And Atmospheric Profiling Systems, Rezaul Mahmood, Megan Schargorodski, Eric Rappin, Melissa Griffin, Patrick Collins, Kevin Knupp, Andrew Quilligan, Ryan Wade, Kevin Cary, Stuart Foster

School of Natural Resources: Faculty Publications

A total solar eclipse traversed the continental United States on 21 August 2017. It was the first such event in 99 years and provided a rare opportunity to observe the atmospheric response from a variety of instrumented observational platforms. This paper discusses the highquality observations collected by the Kentucky Mesonet (www.kymesonet.org), a research-grade meteorological and climatological observation network consisting of 72 stations and measuring air temperature, precipitation, relative humidity, solar radiation, wind speed, and wind direction. The network samples the atmosphere, for most variables, every 3 s and then calculates and records observations every 5 min. During the total solar …

Physical And Chemical Properties Of Soils In Gambari Forest Reserve Near Ibadan, South Western Nigeria., Akintola O. Opeyemi Dr, Bodede Idayat Adewunmi Dr, Abiola Isaac Oluwaseyi Dr

Journal of Bioresource Management

The different features of soil greatly affect the flora and vegetative diversity of a forest. The physical and chemical characteristics of soils in Onigambari Forest Reserve were evaluated to assess the fertility and productivity status of the soils. Fifteen soil samples collected from different sample locations were analyzed for soil texture (sand, silt and clay), bulk density, porosity, pH, organic matter, total nitrogen, available phosphorus, exchangeable bases (Na, K, Ca and Mg) and available micronutrients (Zn, Cu, Fe and Mn). Texturally, the studied soils were loamy sand and sandy loam with percentage of sands (71.2-84.2 %), silts (7.4-10.4 %) and …

Temperature Impacts On The Cardiac Activity Of The Snail Pomacea Canaliculata From Shatt Al-Arab Region, Basrah, Iraq, Malik H. Ali, Hanaa H. Mohammed, Huda K. Ahmed

Baghdad Science Journal

The effects of temperature on an exotic aquatic snail Pomacea canaliculata (Lamarck, 1819) collected from the Shatt Al-Arab intertidal zone were investigated. A series of laboratory experiments were conducted during the summer period of 2017. Individuals of new born snails hatched in the laboratory from adult snails were collected from Shatt Al-Arab intertidal zone, and subjected to five fixed temperatures: 15, 25, 35, 40 and 45 Cº, after short term thermal acclimation. The heartbeats (HB) were counted at each temperature level. The results showed significant direct increase of HB from 15 Cº (19.8 HB/min) up to 25 Cº (76 HB/min) …

Contested American Dominance: Global Order In An Era Of Rising Powers, Salvador Santino F. Regilme Jr., James Parisot

Sociology Faculty Publications

The goal of this chapter is to present an analytic overview of what the potential of American decline means for rising powers on a global scale. The chapter argues that while indicators suggest American power has been declining, the shape this takes and the extent to which it falters will depend upon the contingency of global politics related to overall instability in the international system. To clarify this position: First, the chapter provides a brief overview of the current state of the scholarly and policy debates on the status of American power. Second, it examines the extent to which American …

Economically Viable Methods For Wildfire Protection For Residential Homes In Santa Barbara County, Ryan F. Chiment

Construction Management

Santa Barbara County experiences wildfires often, with fourteen major wildfires occurring in the last thirty years. Title 24, Part 9 of the California Building Code establishes the minimum building requirements for fire protection in residential construction, but there are many ways to protect a home from wildfires that go beyond the minimum requirements established in the building code. The goal of this paper is to assess the perceived increase in value to Santa Barbara County homeowners of wildfire protective measures for their homes, and to determine realistic methods for wildfire protection that are within the budget of these homeowners. This …

Keynote Speaker - The Impact Of Climate Change On Canadian-U.S. Defense, The Honorable John Mckay

Canada-United States Law Journal

No abstract provided.