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Esma Renews Its Decision Requiring Net Short Position Holders To Report Positions 0.1% And Above, European Securities And Markets Authority

Documents

No abstract provided.

Correction: Moxley, R.A., Et Al. Intimate Attachment Of Escherichia Coli O157:H7 To Urinary Bladder Epithelium In The Gnotobiotic Piglet Model. Microorganisms 2020, 8, 263, Rodney A. Moxley, Tom W. Bargar, Stephen D. Kachman, Diane R. Baker, David Francis

School of Veterinary and Biomedical Sciences: Faculty Publications

The authors wish to make the following corrections to this paper [1]: On page 2, the sentence that reads, “Hence, EHEC is a rare but established cause of HUS in children and adults.” should read, “Hence, EHEC is a rare but established cause of UTI-associated HUS in children and adults.” On page 4, the sentence that reads, “As noted previously, 14 of 126 (13.3%) piglets orally inoculated with EHEC O157:H7 strains developed mild to moderate purulent cystitis within 8 d PI [25] (Table 1).” should read, “As noted previously, 14 of 105 (13.3%) piglets orally inoculated with EHEC O157:H7 strains …

Local Injections Of Β-Ngf Accelerates Endochondral Fracture Repair By Promoting Cartilage To Bone Conversion., Kevin O. Rivera, Fabrizio Russo, Ryan M. Boileau, Ryan E. Tomlinson, Theodore Miclau, Ralph S. Marcucio, Tejal A. Desai, Chelsea S. Bahney

Department of Orthopaedic Surgery Faculty Papers

There are currently no pharmacological approaches in fracture healing designed to therapeutically stimulate endochondral ossification. In this study, we test nerve growth factor (NGF) as an understudied therapeutic for fracture repair. We first characterized endogenous expression of Ngf and its receptor tropomyosin receptor kinase A (TrkA) during tibial fracture repair, finding that they peak during the cartilaginous phase. We then tested two injection regimens and found that local β-NGF injections during the endochondral/cartilaginous phase promoted osteogenic marker expression. Gene expression data from β-NGF stimulated cartilage callus explants show a promotion in markers associated with endochondral ossification such as Ihh, Alpl, …

Services Provided By Local Governments And The Sources Of Revenue To Fund Them, Final Installment Of Tacir's Study On Local Government Revenue And Services, Tennessee. Advisory Commission On Intergovernmental Relations.

Miscellaneous Reports

No abstract provided.

Bioinformatics Metadata Extraction For Machine Learning Analysis, Zachary Tom

Master's Projects

Next generation sequencing (NGS) has revolutionized the biological sciences. Today, entire genomes can be rapidly sequenced, enabling advancements in personalized medicine, genetic diseases, and more. The National Center for Biotechnology Information (NCBI) hosts the Sequence Read Archive (SRA) containing vast amounts of valuable NGS data. Recently, research has shown that sequencing errors in conventional NGS workflows are key confounding factors for detecting mutations. Various steps such as sample handling and library preparation can introduce artifacts that affect the accuracy of calling rare mutations. Thus, there is a need for more insight into the exact relationship between various steps of the …

News Reporting On Trump's Covid-19 Treatments: Should Broadcasters Have To Disclose Their Being Potentially Dangerous?, Dr. Joel Timmer

Washington Journal of Law, Technology & Arts

During the early months of the COVID-19 pandemic in 2020, President Trump touted a number of treatments that many medical professionals considered dangerous. These treatments include hydroxychloroquine and disinfectants, which if misused could cause a patient’s death. This prompted Free Press to file an emergency petition with the FCC, arguing that broadcasters who report on Trump’s claims about these treatments without highlighting their dangers could be in violation of the Commission’s broadcast hoax rule. Free Press also requested the FCC require that broadcasters include disclaimers when reporting on such claims. This article examines whether the broadcast hoax rule has been …

Student Success In Virtual Versus In-Person Learning During A Direct Instruction Math Intervention Course, Christina Lindmeier

Dissertations, Theses, and Projects

Public education has always been thought of as being completed in a brick and mortar setting with students in desks and teachers at the front of the classroom. Students interact with their peers and learn through lecture and hands-on activities. This general understanding was quickly changed in the spring of 2020 due to the Covid-19 pandemic. Schools had to shift from in person learning to online learning with little to no planning time. As schools began to transition back in the fall of 2020, school boards had to make the choice of continuing all virtual learning, creating a hybrid learning …

Short-Term Direct Reading Instruction For 2nd Grade Students Using Horizons Fast Track A-B, Emily Dempster

Dissertations, Theses, and Projects

Children who read proficiently by third grade are four times more likely to graduate from high school (Hernandez, 2011). This school-based project explored the effects of Horizons Fast Track A-B phonics intervention on oral reading fluency (ORF) progress of three second grade students. Students received 40-minute lessons, twice a week for three weeks. Lesson activities ranged from identifying letter sounds to story comprehension. Students were progress monitored weekly at the second- grade level using one-minute ORF probes. It appeared that the intervention was not beneficial for these students. Discussion includes possible changes that could have been made to make the …

An Interdisciplinary Analysis Of Health Equity As Evaluated Through The Covid-19 Response Concerning French-Speaking Refugees., Margaret Henning

Honors Theses

A collaborative approach is needed to understand the multifaceted medical bias and inequalities experienced by refugee camps of Francophone (French-speaking) nations. A combination of interest and passion for anthropology, medicine, and the French language presents a unique window of intersectionality to analyze this issue. Through a comprehensive review of literature published in both English and French languages, and connections with directors and leaders of refugee camps located in France and French-speaking African nations, we have elucidated a few examples of alarming medical bias experienced by both refugees and migrants. Although an exhaustive list of medical bias could be presented on …

M.N.V. Holdings, L.C., Appelant V. 200 South Llc, Appelle : Brief Of Appellant, Utah Court Of Appeals

Utah Court of Appeals Briefs (2020 –)

Appeal from the Third Judicial District Court, Salt Lake County Honorable Andrew Stone

Greggory J. Savage Gregory S. Roberts Ray Quinney & Nebeker Attorneys for 200 South LLC

Scott 0. Mercer J. Adam Knorr Kesler & Rust Attorneys for M N. V Holdings, L.C.

Sea Otter Diet Composition With Respect To Recolonization, Life History, And Season In Southern Southeast Alaska, Nicole Laroche

Fisheries

Until translocation efforts in the 1960s, sea otters (Enhydra lutris) were absent from Southeast Alaska due to extirpation by the fur trade in the 18th and 19th centuries. About 400 sea otters were reintroduced to six Southeast Alaska locations, including two sites near Prince of Wales Island in southern Southeast Alaska. The most recent US Fish and Wildlife Service population count, completed in 2012, estimated that about 25,000 sea otters inhabited Southeast Alaska. Sea otters will reduce invertebrate prey biomass when recolonizing an area. By quantifying sea otter diets and caloric intake according to recolonization patterns, we can better understand …

Spawning Migration Characteristics And Ecology Of Eulachon (Thaleichthys Pacificus), Robert E. Spangler

Fisheries

Eulachon Thaleichthys pacificus has experienced dramatic reductions in their distribution and abundance along the west coast of North America. This prompted the listing of this species as "Threatened" under the U.S. Endangered Species Act (ESA) of 1973 for populations found in the southern portions of their range, but not in Alaska. Key gaps in knowledge of Eulachon spawning ecology exist that impede population monitoring efforts and habitat protection. Currently, many monitoring efforts ignore estuaries as possible spawning habitat leading to inaccurate estimates of population abundance and trends. Furthermore, estuaries are not designated as critical spawning habitat for Eulachon. This is …

Toward Non-Invasive Measurement Of Atmospheric Temperature Using Vibro-Rotational Raman Spectra Of Diatomic Gases, Tyler Capek, Jacek Borysow, Claudio Mazzoleni, Massimo Moraldi

Michigan Tech Publications, Part 1

We demonstrate precise determination of atmospheric temperature using vibro-rotational Raman (VRR) spectra of molecular nitrogen and oxygen in the range of 292–293 K. We used a continuous wave fiber laser operating at 10 W near 532 nm as an excitation source in conjunction with a multi-pass cell. First, we show that the approximation that nitrogen and oxygen molecules behave like rigid rotors leads to erroneous derivations of temperature values from VRR spectra. Then, we account for molecular non-rigidity and compare four different methods for the determination of air temperature. Each method requires no temperature calibration. The first method involves fitting …

Tracing Carbon Sources Of Southern Beaufort Sea And Chukchi Sea Polar Bears Using Stable Isotope Analyses, Malia E.K. Smith

Marine Biology

The Southern Beaufort Sea (SBS) polar bear (Ursus maritimus) subpopulation has declined in response to sea ice loss, while the Chukchi Sea (CS) subpopulation appears stable. The substantial population decline in the SBS subpopulation in recent years is concurrent with increases in the proportion of polar bears coming on shore, and the duration they spend there. Both of these changes have been associated with the loss of access to their primary sea ice habitat, which is mainly used as a platform to hunt seals. The first objective of this study was to determine if the SBS and CS polar bear …

Genomic Signatures Of Optimal Growth Temperature In The Family Colwelliaceae, Anais Gentilhomme

Oceanography

The temperature range supporting growth defines a complex physiological phenotype that depends on interactions between an organism's genome and its environment. Its implications are widespread since small changes in optimal growth temperature (OGT) can alter an organism's ability to inhabit an ecological niche. Thus, organisms with extreme thermal growth traits (e.g., psychrophilic, with OGT < 15℃, or thermophilic, with OGT 60 -80℃) may be useful for identifying promising targets when searching for life on other planets, as well as predicting population dynamics in a warming Arctic. We performed comparative genomic analyses of bacteria newly isolated from Arctic sea ice that were affiliated with Colwelliaceae, a family of Gammaproteobacteria that contains many psychrophilic strains, to identify genomic factors that might be used to predict OGT. A phylogenomic analysis of 67 public and 39 newly-sequenced strains, was used to construct an updated phylogenetic tree of Colwelliaceae, of which at least two genera were well represented. To augment the previously reported OGTs of 26 strains, we measured growth rates at −1, 4, 11, and 17 ℃ to determine the OGTs of these 39 new strains of Colwelliaceae. We found that growth rates among all isolates were comparable at −1℃, but varied widely above 10 ℃, indicating higher variability in the ability to tolerate warmer temperatures. To analyze the phenotypic differences on a genomic level, we examined indices of amino acid substitutions that have previously been linked with cold adaptation via an increase in protein flexibility. We found that these indices were significantly correlated with OGT at the whole genome level, although the sign of some correlations were opposite of the predicted positive correlation between temperature and the indices. Using these data, we fit a multiple linear regression model for OGT within the Colwelliaceae family that incorporates the three most informative amino acid indices: GRAVY, Aliphatic Index, and Acidic Residue Proportion. Additionally, a putative cold-adaptive gene cassette was identified that was likely introduced by horizontal gene transfer between two closely related clades with different OGTs. These contributions offer key insights into OGT variability and its underlying genomic foundation in the family Colwelliaceae.

Malware Classification Using Lstms, Dennis Dang

Master's Projects

Signature and anomaly based detection have long been quintessential techniques used in malware detection. However, these techniques have become increasingly ineffective as malware becomes more complex. Researchers have therefore turned to deep learning to construct better performing models. In this project, we create four different long-short term memory (LSTM) models and train each model to classify malware by family type. Our data consists of opcodes extracted from malware executables. We employ techniques used in natural language processing (NLP) such as word embedding and bidirection LSTMs (biLSTM). We also use convolutional neural networks (CNN). We found that our model consisting of …

State Of Idaho V. Rachel Elizabeth Luna Appellant's Brief Dckt. 47760

Not Reported

No abstract provided.

State V. Ybarra Appellant's Brief Dckt. 48016

Not Reported

No abstract provided.

State V. Scruggs Respondent's Brief Dckt. 48020

Not Reported

No abstract provided.

State V. Suckow Appellant's Brief Dckt. 48047

Not Reported

No abstract provided.

State V. Clapp Appellant's Brief Dckt. 48049

Not Reported

No abstract provided.

State V. Lake Respondent's Brief Dckt. 48057

Not Reported

No abstract provided.

State V. Mallak Respondent's Brief Dckt. 48169

Not Reported

No abstract provided.

Analytical And Clinical Sample Performance Characteristics Of The Onclarity Assay For The Detection Of Human Papillomavirus, Stephen Young, Laurence Vaughan, Karen Yanson, Karen Eckert, Aojun Li, James Harris, Aaron Ermel, James A. Williams, Mohammad Al-Ghoul, Catherine L. Cammarata, Stephanie N. Taylor, Ronald Luff, Charles K. Cooper, Barbara Van Der Pol

Pathology Research and Scholarship

The objective of this study was to determine the result reproducibility and performance of the BD Onclarity human papillomavirus (HPV) assay (Onclarity) on the BD Viper LT platform using both contrived and clinical specimens. Reproducibility was assessed in BD SurePath liquid-based cytology (LBC) medium (SurePath) using contrived panels (HPV genotype 16 [HPV16] positive, HPV18 positive, or HPV45 positive) or clinical specimens (HPV16, -18, -31, -33/58, -45, or -52 positive or HPV negative). In addition, specimens from 3,879 individuals from the Onclarity trial were aliquoted prior to or following cytology processing and tested for HPV. Finally, specimens were collected using either …

Growth Strategies Through Mergers And Acquisitions In Knowledge-Based Companies – The Case For Architect/Engineer (A/E) Professional Service Firms (Psfs), Terry A. Ruhl

College of Business Theses and Dissertations

Analyses of mergers and acquisitions (M&A) across industries are prevalent in the literature. Yet, this research reveals that at least half, if not more, of all M&A activity fails to meet strategic, operational, and financial objectives, and can result in declining employee and customer satisfaction. The research herein develops a model framework for alternative growth strategies in the architecture/engineering (A/E) industry, with a specific focus on the antecedents of successful M&A among A/E professional service firms (PSFs).At the center of the model is the Resource Based View of the Firm, where leadership capacity, cash, and capital flows yield an affordable …

Uncertainty Quantification In Unconventional Reservoirs Using Conventional Bootstrap And Modified Bootstrap Methodology, Chukwuemeka Okoli

Engineering

Various uncertainty quantication methodologies are presented using a combination of several deterministic decline curve analysis models and two bootstrapping algorithms. The bootstrapping algorithms are the conventional bootstrapping method (CBM) and the modied bootstrapping method (MBM). The combined deterministic-stochastic combination models are applied to 126 sample wells from the Permian basin. Results are presented for 12 to 72 months of production hindcast given an average well production history of 120 months. Previous researchers used the Arps model and both conventional and modied bootstrapping with block re-sampling techniques to reliably quantify uncertainty in production forecasts. In this work, we applied both stochastic …

Effects Of Sea Ice Seasonal Evolution And Oil Properties On Crude Oil Upward Migration Through Sea Ice, Marc Oggier

Geosciences

Sea ice plays an essential role in polar ecosystems as a habitat for organisms at the base of the food web. Receding Arctic perennial sea ice, potential oil and gas reserves, and increasing industrial activities in the Arctic are likely to increase oil extraction and transport in the maritime Arctic. Despite a decrease in summer sea ice extent, Arctic waters remain covered with sea ice for much of the year, increasing the risk of an oil spill in and under Arctic sea ice. This dissertation addresses the need for a quantitative understanding of the timing of and constraints on oil …

The Reproductive Biology Of Yelloweye Rockfish (Sebastes Ruberrimus) In Prince William Sound And The Northern Gulf Of Alaska, Donald E. Arthur

Fisheries

Over the last half century, Yelloweye Rockfish Sebastes ruberrimus have experienced dramatic declines along the West Coast of the United States and British Columbia. Efforts have been made throughout the species' range to rebuild and sustainably manage stocks, including the introduction of a Statewide Rockfish Initiative by the State of Alaska, which intends to develop management strategies for Yelloweye Rockfish in the Gulf of Alaska. To support this effort and address information gaps in Yelloweye Rockfish reproductive biology throughout their range, I estimated important reproductive parameters and life history information for Yelloweye Rockfish in Prince William Sound and the Northern …

Reproduction And Stress Response Endocrinology In Blue (Balaenoptera Musculus) And Gray (Eschrichtius Robustus) Whales, Valentina Melica

Fisheries

Identification of biomarkers that reflect physiological status is fundamental for assessing population health, as well as providing more accurate estimates of life history parameters. Blue (Balaenoptera musculus) and gray (Eschrichtius robustus) whale populations feed on lower trophic levels and migrate between the eastern Tropical and the eastern North Pacific Ocean. With increasing disturbances (e.g., changing environment and human activities), understanding the stress response, resultant coping mechanisms, and the subsequent effects on reproduction, is of growing importance. While extensive knowledge is available on photo-identification and ecology of these two species, information on physiology is limited and what exists is outdated. This …

Changing Glaciers In The Brooks Range And Western Chugach Mountains, Alaska: Mass Loss, Runoff Increase, And Supraglacial Volcanic Tephra Coverage, Jason Geck

Geosciences

Glaciers in Alaska cover over ~87,000 km² (~ 6 % of the state) with most glaciers thinning and retreating at an increasing rate. The thinning and retreating of glaciers worldwide can have an immediate socio-economic implication in addition to the longer-term glacier meltwater contribution to sea level rise. This dissertation investigated Alaskan glaciers in the Brooks Range for mass loss and area reductions over the period 1970-2001 (Chapter 2), historic mass balance and runoff for Eklutna Glacier, located in western Chugach Mountains, using a temperature index model over 1984-2019 period (Chapter 3), and the persistence of tephra from a volcanic …