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2020

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Daniel 11 Decoded: An Exegetical, Historical, And Theological Study [Review] / Doukhan, Jacques., Martin Pröbstle Jan 2020

Daniel 11 Decoded: An Exegetical, Historical, And Theological Study [Review] / Doukhan, Jacques., Martin Pröbstle

Andrews University Seminary Studies (AUSS)

Book Review


Daniel 11 Decoded: An Exegetical, Historical, And Theological Study [Review] / Doukhan, Jacques., Roy Gane Jan 2020

Daniel 11 Decoded: An Exegetical, Historical, And Theological Study [Review] / Doukhan, Jacques., Roy Gane

Andrews University Seminary Studies (AUSS)

Book Review


The Hermeneutics Of The Biblical Writers: Learning To Interpret Scripture From The Prophets And Apostles [Review] / Chou, Abner., Silvia Bacchiocchi Jan 2020

The Hermeneutics Of The Biblical Writers: Learning To Interpret Scripture From The Prophets And Apostles [Review] / Chou, Abner., Silvia Bacchiocchi

Andrews University Seminary Studies (AUSS)

Book Review


Scribes And Scrolls At Qumran [Review] / Crawford, Sidnie White., Rodrigo Galiza Jan 2020

Scribes And Scrolls At Qumran [Review] / Crawford, Sidnie White., Rodrigo Galiza

Andrews University Seminary Studies (AUSS)

Book Review


Saying No To God: A Radical Approach To Reading The Bible Faithfully [Review] / Korpman, Matthew J., André Reis Jan 2020

Saying No To God: A Radical Approach To Reading The Bible Faithfully [Review] / Korpman, Matthew J., André Reis

Andrews University Seminary Studies (AUSS)

Book Review


The Sermon On The Mount And Human Flourishing: A Theological Commentary [Review] / Pennington, Jonathan., Ernest Bursey Jan 2020

The Sermon On The Mount And Human Flourishing: A Theological Commentary [Review] / Pennington, Jonathan., Ernest Bursey

Andrews University Seminary Studies (AUSS)

Book Review


Some Hermeneutical Principles For The Biblical Historian, Paul J. Ray Jr Jan 2020

Some Hermeneutical Principles For The Biblical Historian, Paul J. Ray Jr

Andrews University Seminary Studies (AUSS)

While the grammatical-historical method of interpretation, which focuses on the languages of the biblical text and its historical backgrounds to arrive at meaning, has long been the interpretive procedure of choice in many faith communities, modern methods of biblical study have tended to move away from text-historical, to text-exclusive or more reader-centered hermeneutics. Unfortunately, this trend has either basically removed history from the interpretive arena or left the field open to simplistic and sensationalistic historical explanations. Since one’s view of biblical history is predicated on background matters such as conceptions of revelation, inspiration, the Bible, and even history itself, I …


Trust And Doubt: Perceptions Of Divine Inspiration In Seventh-Day Adventist History [Review] / Kaiser, Denis., Alberto R. Timm Jan 2020

Trust And Doubt: Perceptions Of Divine Inspiration In Seventh-Day Adventist History [Review] / Kaiser, Denis., Alberto R. Timm

Andrews University Seminary Studies (AUSS)

Book Review


A Vision-Based Machine Learning Method For Barrier Access Control Using Vehicle License Plate Authentication, Kh Tohidul Islam, Ram Gopal Raj, Syed Mohammed Shamsul Islam, Sudanthi Wijewickrema, Md Sazzad Hossain, Tayla Razmovski, Stephen O’Leary Jan 2020

A Vision-Based Machine Learning Method For Barrier Access Control Using Vehicle License Plate Authentication, Kh Tohidul Islam, Ram Gopal Raj, Syed Mohammed Shamsul Islam, Sudanthi Wijewickrema, Md Sazzad Hossain, Tayla Razmovski, Stephen O’Leary

Research outputs 2014 to 2021

Automatic vehicle license plate recognition is an essential part of intelligent vehicle access control and monitoring systems. With the increasing number of vehicles, it is important that an effective real-time system for automated license plate recognition is developed. Computer vision techniques are typically used for this task. However, it remains a challenging problem, as both high accuracy and low processing time are required in such a system. Here, we propose a method for license plate recognition that seeks to find a balance between these two requirements. The proposed method consists of two stages: detection and recognition. In the detection stage, …


Igg Glycosylation Profile And The Glycan Score Are Associated With Type 2 Diabetes In Independent Chinese Populations: A Case-Control Study, Zhiyuan Wu, Haibin Li, Di Liu, Lixin Tao, Jie Zhang, Baolu Liang, Xiangtong Liu, Xiaonan Wang, Xia Li, Youxin Wang, Wei Wang, Xiuhua Guo Jan 2020

Igg Glycosylation Profile And The Glycan Score Are Associated With Type 2 Diabetes In Independent Chinese Populations: A Case-Control Study, Zhiyuan Wu, Haibin Li, Di Liu, Lixin Tao, Jie Zhang, Baolu Liang, Xiangtong Liu, Xiaonan Wang, Xia Li, Youxin Wang, Wei Wang, Xiuhua Guo

Research outputs 2014 to 2021

Background. The relationship between the IgG glycan panel and type 2 diabetes remains unclear in Chinese population. We aimed to investigate the association of the IgG glycan profile and glycan score with type 2 diabetes. Methods. In the discovery population, 162 individuals diagnosed with type 2 diabetes and 162 matched controls from Beijing health management cohort were included. We analyzed the IgG glycan profile and composed a glycan score for type 2 diabetes. Findings were validated in the replication population from Beijing Xuanwu community cohort (280 cases and 508 controls). Area under curve (AUC) using 10-fold and bootstrap validation, net …


Docosahexaenoic Acid-Rich Fish Oil Supplementation Reduces Kinase Associated With Insulin Resistance In Overweight And Obese Midlife Adults, Rohith N. Thota, Jessica I. Rosato, Tracy L. Burrows, Cintia B. Dias, Kylie A. Abbott, Ralph N. Martins, Manohar L. Garg Jan 2020

Docosahexaenoic Acid-Rich Fish Oil Supplementation Reduces Kinase Associated With Insulin Resistance In Overweight And Obese Midlife Adults, Rohith N. Thota, Jessica I. Rosato, Tracy L. Burrows, Cintia B. Dias, Kylie A. Abbott, Ralph N. Martins, Manohar L. Garg

Research outputs 2014 to 2021

Targeting kinases linked to insulin resistance (IR) and inflammation may help in reducing the risk of type 2 diabetes (T2D) and Alzheimer’s disease (AD) in its early stages. This study aimed to determine whether DHA-rich fish oil supplementation reduces glycogen synthase kinase (GSK-3), which is linked to both IR and AD. Baseline and post-intervention plasma samples from 58 adults with abdominal obesity (Age: 51.7 ± 1.7 years, BMI: 31.9 ± 0.8 kg/m2) were analysed for outcome measures. Participants were allocated to 2 g DHA-rich fish oil capsules (860 mg DHA + 120 mg EPA) (n = 31) or placebo capsules …


Absolute And Relative Strength, Power And Physiological Characteristics Of Indian Junior National-Level Judokas, Dale M. Harris, Kristina Kendall, G. Gregory Haff, Christopher Latella Jan 2020

Absolute And Relative Strength, Power And Physiological Characteristics Of Indian Junior National-Level Judokas, Dale M. Harris, Kristina Kendall, G. Gregory Haff, Christopher Latella

Research outputs 2014 to 2021

The physical qualities that underpin successful junior judokas requires continuing investigation. We investigated the physical and physiological characteristics of junior national level judokas. We tested 25 (15 male, 10 female) Indian judokas for absolute and relative strength (back-squat and bench-press one-repetition maximum (1RM) as well as isometric handgrip), aerobic (RAMP test) and lower-body anaerobic power (Wingate 6-s sprint and countermovement jump), change-of-direction (5-0-5 test) and speed (30 m sprint). Athletes were grouped according to national-level competition placing (gold-medal winners (GM; n = 8), all medal winners (MW; n = 13), non-medallists (NM; n = 12), and NM plus silver and …


Plasma Transferrin And Hemopexin Are Associated With Altered Aβ Uptake And Cognitive Decline In Alzheimer’S Disease Pathology, Azhaar Ashraf, Nicholas J. Ashton, Pratishtha Chatterjee, Kathryn Goozee, Kaikai Shen, Jurgen Fripp, David Ames, Christopher Rowe, Colin L. Masters, Victor Villemagne, Abdul Hye, Ralph N. Martins, Po-Wah So, Aibl Jan 2020

Plasma Transferrin And Hemopexin Are Associated With Altered Aβ Uptake And Cognitive Decline In Alzheimer’S Disease Pathology, Azhaar Ashraf, Nicholas J. Ashton, Pratishtha Chatterjee, Kathryn Goozee, Kaikai Shen, Jurgen Fripp, David Ames, Christopher Rowe, Colin L. Masters, Victor Villemagne, Abdul Hye, Ralph N. Martins, Po-Wah So, Aibl

Research outputs 2014 to 2021

Background:Heme and iron homeostasis is perturbed in Alzheimer’s disease (AD); therefore, the aim of the studywas to examine the levels and association of heme with iron-binding plasma proteins in cognitively normal (CN),mild cognitive impairment (MCI), and AD individuals from the Australian Imaging, Biomarker and Lifestyle FlagshipStudy of Ageing (AIBL) and Kerr Anglican Retirement Village Initiative in Ageing Health (KARVIAH) cohorts.Methods:Non-targeted proteomic analysis by high-resolution mass spectrometry was performed to quantify relativeprotein abundances in plasma samples from 144 CN individuals from the AIBL and 94 CN from KARVIAH cohorts and21 MCI and 25 AD from AIBL cohort. ANCOVA models were utilized …


The Study Protocol For A Pseudo-Randomised Pre-Post Designed Controlled Intervention Trial To Study The Effects Of A 7-Week Cooking Program On Self-Efficacy And Biomarkers Of Health: The Ecu Lifestyle And Biomarkers Get Connected Study (Eculabjmof) Including The Jamie’S Ministry Of Food Wa Participant Experience, Joanna Rees, Claus C. Christophersen, Joshua R. Lewis, Johnny Lo, Ros Sambell, Leesa Costello, Cailyn Walker, Matt F. Byrne, Mary C. Boyce, Robert U. Newton, Amanda Devine Jan 2020

The Study Protocol For A Pseudo-Randomised Pre-Post Designed Controlled Intervention Trial To Study The Effects Of A 7-Week Cooking Program On Self-Efficacy And Biomarkers Of Health: The Ecu Lifestyle And Biomarkers Get Connected Study (Eculabjmof) Including The Jamie’S Ministry Of Food Wa Participant Experience, Joanna Rees, Claus C. Christophersen, Joshua R. Lewis, Johnny Lo, Ros Sambell, Leesa Costello, Cailyn Walker, Matt F. Byrne, Mary C. Boyce, Robert U. Newton, Amanda Devine

Research outputs 2014 to 2021

Background: Australia, like other nations, has experienced a shift in dietary patterns away from home cooking of nutritious foods, towards a reliance on pre-prepared convenience meals. These are typically energy-dense, nutrient-poor and contribute to the rising prevalence of obesity and chronic disease burden. The aims of this study were to evaluate whether a community-based cooking program instigated a change to participants’ skills, attitudes, knowledge, enjoyment and satisfaction of cooking and cooking confidence (self-efficacy). Methods: The pseudo-random, pre-post study design consisted of an intervention and a control group. Participant recruitment and group allocation was based on their program start dates. Intervention …


Dual Tasking Impairments Are Associated With Striatal Pathology In Huntington’S Disease, Johnny Lo, Alvaro Reyes, Timothy S. Pulverenti, Timothy J. Rankin, Danielle M. Bartlett, Pauline Zaenker, Grant Rowe, Kirk Feindel, Govinda Poudel, Nellie Georgiou-Karistianis, Mel R. Ziman, Travis M. Cruickshank Jan 2020

Dual Tasking Impairments Are Associated With Striatal Pathology In Huntington’S Disease, Johnny Lo, Alvaro Reyes, Timothy S. Pulverenti, Timothy J. Rankin, Danielle M. Bartlett, Pauline Zaenker, Grant Rowe, Kirk Feindel, Govinda Poudel, Nellie Georgiou-Karistianis, Mel R. Ziman, Travis M. Cruickshank

Research outputs 2014 to 2021

Background: Recent findings suggest that individuals with Huntington’s disease (HD) have an impaired capacity to execute cognitive and motor tasks simultaneously, or dual task, which gradually worsens as the disease advances. The onset and neuropathological changes mediating impairments in dual tasking in individuals with HD are unclear. The reliability of dual tasking assessments for individuals with HD is also unclear. Objectives: To evaluate differences in dual tasking performance between individuals with HD (presymptomatic and prodromal) and matched controls, to investigate associations between striatal volume and dual tasking performance, and to determine the reliability of dual tasking assessments. Methods: Twenty individuals …


Thermal-Hydraulic Performance In A Microchannel Heat Sink Equipped With Longitudinal Vortex Generators (Lvgs) And Nanofluid, Basel Al Muallim, Mazlan A. Wahid, Hussain A. Mohammed, Mohammed Kamil, Daryoush Habibi Jan 2020

Thermal-Hydraulic Performance In A Microchannel Heat Sink Equipped With Longitudinal Vortex Generators (Lvgs) And Nanofluid, Basel Al Muallim, Mazlan A. Wahid, Hussain A. Mohammed, Mohammed Kamil, Daryoush Habibi

Research outputs 2014 to 2021

In this study, the numerical conjugate heat transfer and hydraulic performance of nanofluids flow in a rectangular microchannel heat sink (RMCHS) with longitudinal vortex generators (LVGs) was investigated at different Reynolds numbers (200-1200). Three-dimensional simulations are performed on a microchannel heated by a constant temperature with five different configurations with different angles of attack for the LVGs under laminar flow conditions. The study uses five different nanofluid combinations of Al2O3 or CuO, containing low volume fractions in the range of 0.5% to 3.0% with various nanoparticle sizes that are dispersed in pure water, PAO (Polyalphaolefin) or ethylene glycol. The results …


A Novel Method For Detecting Morphologically Similar Crops And Weeds Based On The Combination Of Contour Masks And Filtered Local Binary Pattern Operators, Vi Nguyen Thanh Le, Selam Ahderom, Beniamin Apopei, Kamal Alameh Jan 2020

A Novel Method For Detecting Morphologically Similar Crops And Weeds Based On The Combination Of Contour Masks And Filtered Local Binary Pattern Operators, Vi Nguyen Thanh Le, Selam Ahderom, Beniamin Apopei, Kamal Alameh

Research outputs 2014 to 2021

Background: Weeds are a major cause of low agricultural productivity. Some weeds have morphological features similar to crops, making them difficult to discriminate. Results: We propose a novel method using a combination of filtered features extracted by combined Local Binary Pattern operators and features extracted by plant-leaf contour masks to improve the discrimination rate between broadleaf plants. Opening and closing morphological operators were applied to filter noise in plant images. The images at 4 stages of growth were collected using a testbed system. Mask-based local binary pattern features were combined with filtered features and a coefficient k. The classification of …


Static Stretch And Dynamic Muscle Activity Induce Acute Similar Increase In Corticospinal Excitability, Jules Opplertid, Christos Paizis, Athina Papitsa, Anthony J. Blazevich, Carole Cometti, Nicolas Babault Jan 2020

Static Stretch And Dynamic Muscle Activity Induce Acute Similar Increase In Corticospinal Excitability, Jules Opplertid, Christos Paizis, Athina Papitsa, Anthony J. Blazevich, Carole Cometti, Nicolas Babault

Research outputs 2014 to 2021

Even though the acute effects of pre-exercise static stretching and dynamic muscle activity on muscular and functional performance have been largely investigated, their effects on the corticospinal pathway are still unclear. For that reason, this study examined the acute effects of 5×20 s of static stretching, dynamic muscle activity and a control condition on spinal excitability, corticospinal excitability and plantar flexor neuromuscular properties. Fifteen volunteers were randomly tested on separate days. Transcranial magnetic stimulation was applied to investigate corticospinal excitability by recording the amplitude of the motorevoked potential (MEP) and the duration of the cortical silent period (cSP). Peripheral nerve …


Supporting New Graduate Registered Nurse Transition For Safety: A Literature Review Update, Melanie Murray, Deborah Sundin, Vicki Cope Jan 2020

Supporting New Graduate Registered Nurse Transition For Safety: A Literature Review Update, Melanie Murray, Deborah Sundin, Vicki Cope

Research outputs 2014 to 2021

Background: Reports suggest higher incidence of medical errors occur during times of transition for new practitioners, in part due to general staff disruption in the health services and inexperience of those entering the workplace. NGRNs experience a range of challenges on transition to professional practice and their transition experience will impact their ability to provide high quality patient care.

Aim: The aim of this review was to critically appraise the contemporary literature concerning the transition of new graduate registered nurses (NGRNs) and their patient safety knowledge and practices.

Design: A scoping review of research literature.

Methods: The review used key …


Characterizing The Composition Of The Pediatric Gut Microbiome: A Systematic Review, Kane E. Deering, Amanda Devine, Therese A. O’Sullivan, Johnny Lo, Mary C. Boyce, Claus T. Christophersen Jan 2020

Characterizing The Composition Of The Pediatric Gut Microbiome: A Systematic Review, Kane E. Deering, Amanda Devine, Therese A. O’Sullivan, Johnny Lo, Mary C. Boyce, Claus T. Christophersen

Research outputs 2014 to 2021

The consortium of trillions of microorganisms that live inside the human gut are integral to health. Little has been done to collate and characterize the microbiome of children. A systematic review was undertaken to address this gap (PROSPERO ID: CRD42018109599). MEDLINE and EMBASE were searched using the keywords: “healthy preadolescent children” and “gut microbiome” to 31 August 2018. Of the 815 journal articles, 42 met the inclusion criteria. The primary outcome was the relative abundance of bacteria at the phylum, family, and genus taxonomic ranks. α-diversity, short chain fatty acid concentrations, diet, 16S rRNA sequencing region, and geographical location were …


The Challenge Of Monoculturalism: What Books Are Educators Sharing With Children And What Messages Do They Send?, Helen Adam, Caroline Barratt-Pugh Jan 2020

The Challenge Of Monoculturalism: What Books Are Educators Sharing With Children And What Messages Do They Send?, Helen Adam, Caroline Barratt-Pugh

Research outputs 2014 to 2021

The importance of recognising, valuing and respecting a child’s family, culture, language and values is increasingly articulated in educational policy. Diversity and inclusion are central themes of the guiding principles of early childhood education and care in Australia. Children’s literature can be a powerful tool for extending children’s knowledge and understandings of themselves and others who may be different culturally, socially or historically. However, evidence suggests many settings provide monocultural book collections which are counterproductive to principles of diversity. This paper reports on a larger study investigating factors and relationships influencing the use of children’s literature to support principles of …


Corrections To: The Effect Of Nordic Hamstring Exercise Intervention Volume On Eccentric Strength And Muscle Architecture Adaptations: A Systematic Journal Article And Meta-Analyses, Matthew Cuthbert, Nicholas Ripley, John J. Mcmahon, Martin Evans, G. Gregory Haff, Paul Comfort Jan 2020

Corrections To: The Effect Of Nordic Hamstring Exercise Intervention Volume On Eccentric Strength And Muscle Architecture Adaptations: A Systematic Journal Article And Meta-Analyses, Matthew Cuthbert, Nicholas Ripley, John J. Mcmahon, Martin Evans, G. Gregory Haff, Paul Comfort

Research outputs 2014 to 2021

No abstract provided.


A Third Dimension In The Mirror? How Senior Managers Design Products And Organizations, Norbert Bach, Peter Galvin Jan 2020

A Third Dimension In The Mirror? How Senior Managers Design Products And Organizations, Norbert Bach, Peter Galvin

Research outputs 2014 to 2021

Individual CEO characteristics may affect architectural choices through the application of managerial discretion. Systems such as organizations and their products are not purely driven toward modularity because of external forces. Individual CEO characteristics may constitute an additional dimension to established mirroring considerations that impacts both the choice of architecture and the correspondence between product and organization architectures.


Tnf-Block Genotypes Influence Susceptibility To Hiv-Associated Sensory Neuropathy In Indonesians And South Africans, Jessica Gaff, Fitri Octaviana, Prinisha Pillay, Huguette Gaelle Ngassa Mbenda, Ibnu A. Ariyanto, June Ann Gan, Catherine L. Cherry, Peter Kamerman, Simon M. Laws, Patricia Price Jan 2020

Tnf-Block Genotypes Influence Susceptibility To Hiv-Associated Sensory Neuropathy In Indonesians And South Africans, Jessica Gaff, Fitri Octaviana, Prinisha Pillay, Huguette Gaelle Ngassa Mbenda, Ibnu A. Ariyanto, June Ann Gan, Catherine L. Cherry, Peter Kamerman, Simon M. Laws, Patricia Price

Research outputs 2014 to 2021

HIV-associated sensory neuropathy (HIV-SN) is a disabling complication of HIV disease and antiretroviral therapies (ART). Since stavudine was removed from recommended treatment schedules, the prevalence of HIV-SN has declined and associated risk factors have changed. With stavudine, rs1799964*C (TNF-1031) associated with HIV-SN in Caucasians and Indonesians but not in South Africans. Here, we investigate associations between HIV-SN and rs1799964*C and 12 other polymorphisms spanning TNF and seven neighboring genes (the TNF-block) in Indonesians (n = 202; 34/168 cases) and South Africans (n = 75; 29/75 cases) treated without stavudine. Haplotypes were derived using fastPHASE and haplotype networks built with PopART. …


Applying Mobile Augmented Reality (Ar) To Teach Interior Design Students In Layout Plans: Evaluation Of Learning Effectiveness Based On The Arcs Model Of Learning Motivation Theory, Yuh-Shihng Chang, Kuo-Jui Hu, Cheng-Wei Chiang, Artur Lugmayr Jan 2020

Applying Mobile Augmented Reality (Ar) To Teach Interior Design Students In Layout Plans: Evaluation Of Learning Effectiveness Based On The Arcs Model Of Learning Motivation Theory, Yuh-Shihng Chang, Kuo-Jui Hu, Cheng-Wei Chiang, Artur Lugmayr

Research outputs 2014 to 2021

In this paper we present a mobile augmented reality (MAR) application supporting teaching activities in interior design. The application supports students in learning interior layout design, interior design symbols, and the effects of different design layout decisions. Utilizing the latest AR technology, users can place 3D models of virtual objects as e.g., chairs or tables on top of a design layout plan and interact with these on their mobile devices. Students can experience alternative design decision in real-time and increases the special perception of interior designs. Our system fully supports the import of interior deployment layouts and the generation of …


The Effect Of Nordic Hamstring Exercise Intervention Volume On Eccentric Strength And Muscle Architecture Adaptations: A Systematic Review And Meta-Analyses, Matthew Cuthbert, Nicholas Ripley, John J. Mcmahon, Martin Evans, G. Gregory Haff, Paul Comfort Jan 2020

The Effect Of Nordic Hamstring Exercise Intervention Volume On Eccentric Strength And Muscle Architecture Adaptations: A Systematic Review And Meta-Analyses, Matthew Cuthbert, Nicholas Ripley, John J. Mcmahon, Martin Evans, G. Gregory Haff, Paul Comfort

Research outputs 2014 to 2021

Background: Although performance of the Nordic hamstring exercise (NHE) has been shown to elicit adaptations that may reduce hamstring strain injury (HSI) risk and occurrence, compliance in NHE interventions in professional soccer teams is low despite a high occurrence of HSI in soccer. A possible reason for low compliance is the high dosages prescribed within the recommended interventions. The aim of this review was to investigate the effect of NHE-training volume on eccentric hamstring strength and biceps femoris fascicle length adaptations.

Methods: A literature search was conducted using the SPORTDiscus, Ovid, and PubMed databases. A total of 293 studies were …


Examined Lives: The Transformative Power Of Active Interviewing In Narrative Approach, Peter F. Prout, Geoffrey M. Lowe, Christina C. Gray, Sarah Jefferson Jan 2020

Examined Lives: The Transformative Power Of Active Interviewing In Narrative Approach, Peter F. Prout, Geoffrey M. Lowe, Christina C. Gray, Sarah Jefferson

Research outputs 2014 to 2021

An unexamined life is not worth living Socrates (470-399 BC) In this article I reveal transformative experiences stemming from non-verbal communication in the context of active interviewing in narrative research. Drawing upon my recent experience interviewing positive veteran teachers about the relationships they believe vital in maintaining their passion and enthusiasm for teaching, I explore the unique nature of narrative research in fostering intra-personal transformation. The goal of the article is to highlight transformation as an outcome in narrative research, with particular focus upon non-verbal communication in active interviewing. The article is constructed to examine transformation in thinking and understanding …


Cerebrospinal Fluid Neurofilament Light Concentration Predicts Brain Atrophy And Cognition In Alzheimer's Disease, Kunal Dhiman, Veer Bala Gupta, Victor L. Villemagne, Dhamidhu Eratne, Petra L. Graham, Christopher Fowler, Pierrick Bourgeat, Qiao-Xin Li, Steven Collins, Ashley I. Bush, Christopher C. Rowe, Colin L. Masters, David Ames, Eugene Hone, Kaj Blennow, Henrik Zetterberg, Ralph N. Martins Jan 2020

Cerebrospinal Fluid Neurofilament Light Concentration Predicts Brain Atrophy And Cognition In Alzheimer's Disease, Kunal Dhiman, Veer Bala Gupta, Victor L. Villemagne, Dhamidhu Eratne, Petra L. Graham, Christopher Fowler, Pierrick Bourgeat, Qiao-Xin Li, Steven Collins, Ashley I. Bush, Christopher C. Rowe, Colin L. Masters, David Ames, Eugene Hone, Kaj Blennow, Henrik Zetterberg, Ralph N. Martins

Research outputs 2014 to 2021

Introduction
This study assessed the utility of cerebrospinal fluid (CSF) neurofilament light (NfL) in Alzheimer's disease (AD) diagnosis, its association with amyloid and tau pathology, as well as its potential to predict brain atrophy, cognition, and amyloid accumulation.
Methods
CSF NfL concentration was measured in 221 participants from the Australian Imaging, Biomarkers & Lifestyle Flagship Study of Ageing (AIBL).
Results
CSF NfL levels as well as NfL/amyloid β (Aβ42) were significantly elevated in AD compared to healthy controls (HC; P < .001), and in mild cognitive impairment (MCI) compared to HC (P = .008 NfL; P< .001 NfL/Aβ42). CSF NfL and NfL/Aβ42 differentiated AD from HC with an area under the receiver operating characteristic (ROC) curve (AUC) of 0.84 and 0.90, respectively. CSF NfL and NfL/Aβ42 predicted cortical amyloid load, brain atrophy, and cognition.
Discussion
CSF NfL is a biomarker of neurodegeneration, correlating with cognitive impairment and brain neuropathology.


Decrease In 230th In The Amundsen Basin Since 2007: Far-Field Effect Of Increased Scavenging On The Shelf?, Ole Valk, Michiel M. Rutgers Van Der Loeff, Walter Geibert, Sandra Gdaniec, S. Bradley Moran, Kate Lepore, Robert Lawrence Edwards, Yanbin Lu, Viena Puigcorbé, Nuria Casacuberta, Ronja Paffrath, William Smethie, Matthieu Roy-Barman Jan 2020

Decrease In 230th In The Amundsen Basin Since 2007: Far-Field Effect Of Increased Scavenging On The Shelf?, Ole Valk, Michiel M. Rutgers Van Der Loeff, Walter Geibert, Sandra Gdaniec, S. Bradley Moran, Kate Lepore, Robert Lawrence Edwards, Yanbin Lu, Viena Puigcorbé, Nuria Casacuberta, Ronja Paffrath, William Smethie, Matthieu Roy-Barman

Research outputs 2014 to 2021

This study provides dissolved and particulate 230Th and 232Th results as well as particulate 234Th data collected during expeditions to the central Arctic Ocean (GEOTRACES, an international project to identify processes and quantify fluxes that control the distributions of trace elements; sections GN04 and GIPY11). Constructing a time series of dissolved 230Th from 1991 to 2015 enables the identification of processes that control the temporal development of 230Th distributions in the Amundsen Basin. After 2007, 230Th concentrations decreased significantly over the entire water column, particularly between 300 and 1500 m. This decrease is accompanied by a circulation change, evidenced by …


An Exploration Of Machine‐Learning Estimation Of Ground Reaction Force From Wearable Sensor Data, Danica Hendry, Ryan Leadbetter, Kristoffer Mckee, Luke Hopper, Catherine Wild, Peter O’Sullivan, Leon Straker, Amity Campbell Jan 2020

An Exploration Of Machine‐Learning Estimation Of Ground Reaction Force From Wearable Sensor Data, Danica Hendry, Ryan Leadbetter, Kristoffer Mckee, Luke Hopper, Catherine Wild, Peter O’Sullivan, Leon Straker, Amity Campbell

Research outputs 2014 to 2021

This study aimed to develop a wearable sensor system, using machine‐learning models, capable of accurately estimating peak ground reaction force (GRF) during ballet jumps in the field. Female dancers (n = 30) performed a series of bilateral and unilateral ballet jumps. Dancers wore six ActiGraph Link wearable sensors (100 Hz). Data were collected simultaneously from two AMTI force platforms and synchronised with the ActiGraph data. Due to sensor hardware malfunctions and synchronisation issues, a multistage approach to model development, using a reduced data set, was taken. Using data from the 14 dancers with complete multi‐sensor synchronised data, the best single …