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2020

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Decisions In The Dark: Why "Pregnancy Exclusion" Statutes Are Unconstitutional And Unethical, Shea Flanagan Jan 2020

Decisions In The Dark: Why "Pregnancy Exclusion" Statutes Are Unconstitutional And Unethical, Shea Flanagan

Northwestern University Law Review

Advance health care directives are tools that allow people to state their health care treatment wishes or designate a health care proxy in anticipation of being unable to make those decisions in the future, including preferences to remove life-sustaining medical treatment. However, thirty-six states currently have “pregnancy exclusion” laws that require physicians to void the advance directives of pregnant women receiving life-sustaining treatment. This Note assesses the constitutionality and ethics of state pregnancy exclusion statutes by employing a new five-category typology of current pregnancy exclusion laws. This Note argues that all categories of these statutes violate an individual’s constitutional rights …


Data Imperialism: The Gdpr's Disastrous Impact On Africa's E-Commerce Markets, Cara Mannion Jan 2020

Data Imperialism: The Gdpr's Disastrous Impact On Africa's E-Commerce Markets, Cara Mannion

Vanderbilt Journal of Transnational Law

The European Union (EU) recently passed the General Data Protection Regulation--a sweeping regulatory framework that sets a new global standard for the collection, storage, and use of personal data. To ensure far-reaching compliance with the GDPR, the EU has adopted a strict take-it-or-leave-it approach--countries that wish to engage with digital users in the EU must either comply with the GDPR's expansive data obligations or risk losing access to the world's largest trading block.

This presents significant obstacles for several African nations. Notably, no African country currently has domestic laws that comply with the GDPR. Even if they did, several African …


Identification Of Trends In Scientific Communication By Minority Students In An Integrated And Advanced Ninth Grade Science Curriculum, Loren Thalacker Jan 2020

Identification Of Trends In Scientific Communication By Minority Students In An Integrated And Advanced Ninth Grade Science Curriculum, Loren Thalacker

Graduate Research Papers

In the United States, the population of minorities is rapidly increasing. Our nation is facing a shortage in students pursuing STEM careers and it is vital to improve all students’ scientific communication abilities. As our population of minority students is also growing, it is especially important to tap into our potential STEM resources. While the Midwest is less diverse than the rest of the nation, the Waterloo Community School District in Waterloo, Iowa has a large population of minority students. When the district implemented the Next Generation Science Standards it created a problem for students wanting to take advanced science …


Extreme Ultraviolet Quasar Colours From Galex Observations Of The Sdss Dr14q Catalogue, Daniel E. Vanden Berk, Sarah C. Wesolowski, Mary J. Yeckley, Joseph M. Marcinik, Jean M. Quashnock, Lawrence M. Machia, Jian Wu Jan 2020

Extreme Ultraviolet Quasar Colours From Galex Observations Of The Sdss Dr14q Catalogue, Daniel E. Vanden Berk, Sarah C. Wesolowski, Mary J. Yeckley, Joseph M. Marcinik, Jean M. Quashnock, Lawrence M. Machia, Jian Wu

Computer Science Faculty Publications

The rest-frame far to extreme ultraviolet (UV) colour–redshift relationship has been constructed from data on over 480,000 quasars carefully cross-matched between SDSS Data Release 14 and the final GALEX photometric catalogue. UV matching and detection probabilities are given for all the quasars, including dependencies on separation, optical brightness, and redshift. Detection limits are also provided for all objects. The UV colour distributions are skewed redward at virtually all redshifts, especially when detection limits are accounted for. The median GALEX far-UV minus near-UV (FUV − NUV) colour–redshift relation is reliably determined up to z ≈ 2.8, corresponding to rest-frame wavelengths as …


Opening Books And The National Corpus Of Graduate Research, William A. Ingram, Edward A. Fox, Jian Wu Jan 2020

Opening Books And The National Corpus Of Graduate Research, William A. Ingram, Edward A. Fox, Jian Wu

Computer Science Faculty Publications

Virginia Tech University Libraries, in collaboration with Virginia Tech Department of Computer Science and Old Dominion University Department of Computer Science, request $505,214 in grant funding for a 3-year project, the goal of which is to bring computational access to book-length documents, demonstrating that with Electronic Theses and Dissertations (ETDs). The project is motivated by the following library and community needs. (1) Despite huge volumes of book-length documents in digital libraries, there is a lack of models offering effective and efficient computational access to these long documents. (2) Nationwide open access services for ETDs generally function at the metadata level. …


Campus-Wide Student Learning Assessment: Campus Student Learning Outcomes, Academic Year 2019-2020, University Of Minnesota-Morris Jan 2020

Campus-Wide Student Learning Assessment: Campus Student Learning Outcomes, Academic Year 2019-2020, University Of Minnesota-Morris

Institutional Effectiveness and Research Reports

No abstract provided.


Perceptions Of Adaptive Technology Usage In Secondary Math Classrooms, Ryan J. Benjamin Jan 2020

Perceptions Of Adaptive Technology Usage In Secondary Math Classrooms, Ryan J. Benjamin

Graduate Student Dissertations, Theses, Capstones, and Portfolios

Adaptive learning is an emerging technology in education that teachers use to instruct, reinforce, and assess student performance (Smith, 2016). Adaptive technology is powerful because it gives teachers an opportunity to differentiate based on individual needs (Bilous, 2019). It is efficient, allows students to get instant feedback, and can improve the learning experience for students (Matherson & Windle, 2017). Like many other technologies, it is constantly evolving; this makes it difficult to research and update curriculum because programs are constantly changing (Parsons, 2014).

With these changes, teachers are also required to update how they manage their classroom and how they …


Surface And Interface Effects On The Photoexcited Process Of Silver Nanoclusters, And Lead & Cadmium Chalcogenide Nanocrystals, Mohammed Abu Jabed Jan 2020

Surface And Interface Effects On The Photoexcited Process Of Silver Nanoclusters, And Lead & Cadmium Chalcogenide Nanocrystals, Mohammed Abu Jabed

Chemistry and Biochemistry

The surface and interface of the metal nanoclusters and semiconducting nanomaterials play a key role in determining the electronic structure and overall photophysical properties. A single strand DNA stabilizes the metal nanoclusters, but it also influences the structural change, solvation free energy, and photophysical properties. On the other hand, surface and interface states in Pb and Cd chalcogenide nanomaterials affect the phonon mediated hot carrier relaxation. We applied DFT and DFT based non-adiabatic dynamics methods to study the surface and interface’s effects on the photoexcited processes. In the first part, we have studied the Ag nanoclusters' photophysical properties that are …


Seeing The Forest For The Trees: An Exploration Of Student Problem Solving And Reasoning With 1h Nmr Spectral Features, Shannon Yun Anderson Jan 2020

Seeing The Forest For The Trees: An Exploration Of Student Problem Solving And Reasoning With 1h Nmr Spectral Features, Shannon Yun Anderson

Chemistry and Biochemistry

Nuclear magnetic resonance (NMR) spectroscopy is vital to synthesis and provides rich problem-solving opportunities for organic chemistry students. However, little is known about 1H NMR spectroscopy instruction or how students use spectral features in solving. The goal of this dissertation research was to examine how students learn about and solve 1H NMR spectroscopy problems. Organic chemistry textbooks were analyzed for the ways in which spectral features were introduced and incorporated into worked examples and practice problems. Spectral features like the number of signals and chemical shift were covered by problems more frequently, while integration was covered least. Think-aloud interviews were …


First Man And Second Woman: Reflections On The Anniversaries Of Apollo 11 And Cruzan, George J. Annas Jan 2020

First Man And Second Woman: Reflections On The Anniversaries Of Apollo 11 And Cruzan, George J. Annas

Faculty Scholarship

THE United States Supreme Court's decision in Cruzan v. Director, Missouri Department of Health marks its thirtieth anniversary in 2020.' This follows closely after the fiftieth anniversary of the Apollo 11 moon landing.2 Anniversaries provide an opportunity for reflection and to gain perspective. We can, I suggest, gain deeper insights regarding human life and death by considering these two anniversaries together. Apollo 11 may seem far from Nancy Cruzan-but the discovery of disturbing details about the death of Neil Armstrong, the first man on the moon, is a productive introduction to the topic of death in a modern American …


Is Tort Law The Tool For Fixing Reproductive Wrongs?, Christopher Robertson Jan 2020

Is Tort Law The Tool For Fixing Reproductive Wrongs?, Christopher Robertson

Faculty Scholarship

In his 2019 book, Birth Rights and Wrongs: How Medicine and Technology are Remaking Reproduction and the Law, Dov Fox offers a compelling argument for new torts allowing recovery for wrongful reproduction. These torts would include three sorts of cases, those where wrongdoing (whether negligent, reckless, or intentional) caused undesired reproduction; stymied desired reproduction; or confounded reproduction, causing birth of a child different than that intended by the parents. The likely defendants in these torts are gynecologists, urologists, sperm banks, and IVF clinics.


Understanding Violent-Crime Recidivism, J. J. Prescott, Benjamin David Pyle, Sonja B. Starr Jan 2020

Understanding Violent-Crime Recidivism, J. J. Prescott, Benjamin David Pyle, Sonja B. Starr

Faculty Scholarship

People convicted of violent crimes constitute a majority of the imprisoned population but are generally ignored by existing policies aimed at reducing mass incarceration. Serious efforts to shrink the large footprint of the prison system will need to recognize this fact. This point is especially pressing at the time of this writing, as states and the federal system consider large-scale prison releases motivated by the COVID-19 pandemic. Those convicted of violent crimes constitute a large majority of older prisoners, who are extremely vulnerable to the spread of the virus behind bars. Excluding them from protective measures will deeply undermine those …


Federalism, Erisa, And State Single-Payer Health Care, Erin C. Fuse Brown, Elizabeth Mccuskey Jan 2020

Federalism, Erisa, And State Single-Payer Health Care, Erin C. Fuse Brown, Elizabeth Mccuskey

Faculty Scholarship

While federal health reform sputters, states have begun to pursue their own transformative strategies for achieving universal coverage, the most ambitious of which are state-based single-payer plans. Since the passage of the Affordable Care Act in 2010, legislators in twenty-one states have proposed sixty-six unique bills to establish single-payer health care systems. This paper systematically surveys those state legislative efforts and exposes the federalism trap that threatens to derail them: ERISA's preemption of state regulation relating to employer-sponsored health insurance. ERISA's expansive preemption provision creates a narrow, risky path for state regulation to capture the employer health care expenditures crucial …


The State Qui Tam To Enforce Employment Law, Andrew Elmore Jan 2020

The State Qui Tam To Enforce Employment Law, Andrew Elmore

Faculty Scholarship

This Article examines the states' response to Epic Systems v. Lewis, which held enforceable under the Federal Arbitration Act (FAA) mandatory arbitration agreements that require employees to waive their participation in collective and class actions in employment contracts. Recent evidence shows that mandatory arbitration can erode access to justice for and deterrence of employment law claims. States in response are considering qui tam statutes, which assign the state interests in penalties for employment law violations to private enforcers in return for a bounty, to substitute for the loss of class action enforcement after Epic Systems.

These statutes can …


Technologies Of Language Meet Ideologies Of Law, Anya Bernstein Jan 2020

Technologies Of Language Meet Ideologies Of Law, Anya Bernstein

Faculty Scholarship

This Article challenges this new prevailing wisdom, puts legal corpus linguistics in the context of other meaning-making technologies, and suggests an approach for analyzing any technology of language in the law. One of my aims is to caution against technological exceptionalism—a view that computerized, automated, or big-data approaches are somehow special, perhaps more trustworthy, less subjective, and most likely to succeed. Rather, I argue that we should ask the same questions and make the same demands of any method of interpretation.

Any technology, after all, is only as useful as the way it is used: Technology depends on technique. So …


Spatial Dynamics Of Nest Success In White-Throated Sparrows (Zonotrichia Albicollis), Sarah E. Moore Jan 2020

Spatial Dynamics Of Nest Success In White-Throated Sparrows (Zonotrichia Albicollis), Sarah E. Moore

All-Inclusive List of Electronic Theses and Dissertations

White-throated sparrows ( Zonotrichia albicollis ) exhibit two color morphs that breed disassortatively with each other, creating a rare four-sex system. This polymorphism, linked to an inversion on Chromosome 2, also results in two distinct behavior profiles and alternate reproductive strategies. Males settle in territories with characteristics that optimize their reproductive strategy. Overall, the objective of this project was to investigate nest success over a long time-period (18 years). I first sought to create an interpolated risk map for nest failure, a major cause of decreased reproductive success in both sexes. High-density areas, associated with white males, contained more failed …


Special Education Teachers' Perceptions Of Preparation, School Factors, And Programming For Students With Emotional And/Or Behavioral Disabilities, Chauncey E. Amundsen Jan 2020

Special Education Teachers' Perceptions Of Preparation, School Factors, And Programming For Students With Emotional And/Or Behavioral Disabilities, Chauncey E. Amundsen

All-Inclusive List of Electronic Theses and Dissertations

Special educators who serve students with emotional and/or behavioral disabilities (ED/EBD) must be knowledgeable about various interventions, academic supports and modifications, and behavior management techniques that are appropriate and effective in meeting the diverse needs of this student population. This study examined special education teachers perceptions of their preservice training, school factors (e.g., job responsibilities, collegial involvement, and collegial support), and programming for students with ED/EBD. Through an online survey and Skype interviews, quantitative and qualitative data were collected to explore a variety of factors that potentially impact special educators perceived personal and program effectiveness. Due to a small sample …


Study On Countering Extremism And Contemporary Challenges In Islamic Religion Curricula In Saudi Arabia, Alyaa Mohammad Malibari Jan 2020

Study On Countering Extremism And Contemporary Challenges In Islamic Religion Curricula In Saudi Arabia, Alyaa Mohammad Malibari

All-Inclusive List of Electronic Theses and Dissertations

The reform of the Islamic religion curricula by the Ministry of Education in Saudi Arabia within the schools is a process that has been ongoing for quite some time. Major revision of the curricula has been occurring since the events of 9/11. Following the announcement of Vision 2030, curricular reform to move toward moderation has been a monumental task for the Saudi Arabian government. This research study was designed to address two questions regarding the contemporary challenges to counter extremism through the Islamic curriculum and to explore the dynamic solutions needed to have a moderate curriculum. The qualitative study used …


A Study Of Quality Requirement Conveyance For Assignments In Technology And Engineering Masters Degree Programs, Heather J. Mccain Jan 2020

A Study Of Quality Requirement Conveyance For Assignments In Technology And Engineering Masters Degree Programs, Heather J. Mccain

All-Inclusive List of Electronic Theses and Dissertations

Quality requirements are not easy to define. In higher Education, defining quality requirements and communicating those requirements to students may be accomplished through a variety of mechanisms. Students still may not know what it takes to get a good grade on an assignment and may have to wait for an instructor to clarify the assignment. This study was conducted because students and instructors may have different opinions as to which forms of feedforward and what technology are best to convey assignment requirements. The purpose of this study was to determine effective feedforward mechanisms as well as the technology used to …


Contribution Of Advanced Regeneration Of Pinus Radiata D. Don. To Transpiration By A Fragment Of Native Forest In Central Chile Is Out Of Proportion With The Contribution To Sapwood Area, Don A. White, Richard P. Silberstein, Francisco Balocchi-Contreras, Juan Jose Quiroga, Pablo Ramirez De Arellano Jan 2020

Contribution Of Advanced Regeneration Of Pinus Radiata D. Don. To Transpiration By A Fragment Of Native Forest In Central Chile Is Out Of Proportion With The Contribution To Sapwood Area, Don A. White, Richard P. Silberstein, Francisco Balocchi-Contreras, Juan Jose Quiroga, Pablo Ramirez De Arellano

Research outputs 2014 to 2021

The transpiration of Nothofagus glauca (Phil.) Krasser and advanced Pinus radiata D. Don. regeneration was measured in a fragment of native N. glauca forest. Over the eight months of this study, P. radiata contributed approximately 60% of the total stand transpiration. This was out of proportion with the approximately 34% of the stand sapwood area contributed by P. radiata. This was due to the significantly greater sap flux density of the P. radiata compared to the N. glauca between May and October. Though the results are from a small study conducted as part of a larger experiment, it is argued …


Predictors Of Ceasing Or Reducing Statin Medication Following A Large Increase In The Consumer Copayment For Medications: A Retrospective Observational Study, Karla Seamon, Frank Sanfilippo, Max Bulsara, Libby Roughead, Anna Kemp-Casey, Caroline Bulsara, Gerald F. Watts, David Preen Jan 2020

Predictors Of Ceasing Or Reducing Statin Medication Following A Large Increase In The Consumer Copayment For Medications: A Retrospective Observational Study, Karla Seamon, Frank Sanfilippo, Max Bulsara, Libby Roughead, Anna Kemp-Casey, Caroline Bulsara, Gerald F. Watts, David Preen

Research outputs 2014 to 2021

OBJECTIVES:

Previous Australian research has shown that following the 21% increase in patient copayments for medications on the Pharmaceutical Benefits Scheme (PBS) in 2005, the use of lipid-lowering therapy declined by 5%. This study aimed to determine the demographic and clinical characteristics of individuals who continued, reduced or ceased their use of statin medication in 2005.

STUDY TYPE:

Retrospective observational study using routinely collected administrative data.

METHOD:

We used pharmaceutical claims, hospital separations and mortality records from 2000 to 2005 for the Western Australian population. The cohort comprised stable users of statin medication in 2004. Based on changes in statin …


Rdtids: Rules And Decision Tree-Based Intrusion Detection System For Internet-Of-Things Networks, Mohammad Amine Ferrag, Leandros Maglaras, Ahmed Ahmim, Makhlouf Derdour, Helge Janicke Jan 2020

Rdtids: Rules And Decision Tree-Based Intrusion Detection System For Internet-Of-Things Networks, Mohammad Amine Ferrag, Leandros Maglaras, Ahmed Ahmim, Makhlouf Derdour, Helge Janicke

Research outputs 2014 to 2021

This paper proposes a novel intrusion detection system (IDS), named RDTIDS, for Internet-of-Things (IoT) networks. The RDTIDS combines different classifier approaches which are based on decision tree and rules-based concepts, namely, REP Tree, JRip algorithm and Forest PA. Specifically, the first and second method take as inputs features of the data set, and classify the network traffic as Attack/Benign. The third classifier uses features of the initial data set in addition to the outputs of the first and the second classifier as inputs. The experimental results obtained by analyzing the proposed IDS using the CICIDS2017 dataset and BoT-IoT dataset, attest …


Long-Term Maxillary Three Dimensional Changes Following Maxillary Protraction With Or Without Expansion: A Systematic Review And Meta-Analysis, Wei-Cheng Lee, Yi-Shing Shieh, Yu-Fang Liao, Cho-Hao Lee, Chiung Shing Huang Jan 2020

Long-Term Maxillary Three Dimensional Changes Following Maxillary Protraction With Or Without Expansion: A Systematic Review And Meta-Analysis, Wei-Cheng Lee, Yi-Shing Shieh, Yu-Fang Liao, Cho-Hao Lee, Chiung Shing Huang

Journal of Dental Sciences

Background/purpose Maxillary protraction with or without expansion appears to be an effective orthopedic treatment in skeletal class III growing patients, but the long-term effect on maxilla changes is less clear. The aim of this meta-analysis was to evaluate long-term three dimensional skeletal effects on maxilla through face mask (FM) with or without rapid maxillary expansion (RME) in skeletal CIII growing patients. Materials and methods We searched database including PubMed, Science Direct, Embase and Web of Science through Feb 2020. Inclusion criteria were randomized controlled trials or cohort studies recruiting growing patients who received maxillary protraction and/or expansion and comparing the …


Minimizing Blood Loss In Spine Surgery., Christopher Mikhail, Zach Pennington, Paul M Arnold, Darrel S Brodke, Jens R Chapman, Norman Chutkan, Michael D Daubs, John G Devine, Michael G Fehlings, Daniel E Gelb, George M Ghobrial, James S Harrop, Christian Hoelscher, Fan Jiang, John J Knightly, Brian K Kwon, Thomas E Mroz, Ahmad Nassr, K Daniel Riew, Lali H Sekhon, Justin S Smith, Vincent C Traynelis, Jeffrey C Wang, Michael H Weber, Jefferson R Wilson, Christopher D Witiw, Daniel M Sciubba, Samuel K Cho Jan 2020

Minimizing Blood Loss In Spine Surgery., Christopher Mikhail, Zach Pennington, Paul M Arnold, Darrel S Brodke, Jens R Chapman, Norman Chutkan, Michael D Daubs, John G Devine, Michael G Fehlings, Daniel E Gelb, George M Ghobrial, James S Harrop, Christian Hoelscher, Fan Jiang, John J Knightly, Brian K Kwon, Thomas E Mroz, Ahmad Nassr, K Daniel Riew, Lali H Sekhon, Justin S Smith, Vincent C Traynelis, Jeffrey C Wang, Michael H Weber, Jefferson R Wilson, Christopher D Witiw, Daniel M Sciubba, Samuel K Cho

Department of Neurosurgery Faculty Papers

Study Design: Broad narrative review.

Objective: To review and summarize the current literature on guidelines, outcomes, techniques and indications surrounding multiple modalities of minimizing blood loss in spine surgery.

Methods: A thorough review of peer-reviewed literature was performed on the guidelines, outcomes, techniques, and indications for multiple modalities of minimizing blood loss in spine surgery.

Results: There is a large body of literature that provides a consensus on guidelines regarding the appropriate timing of discontinuation of anticoagulation, aspirin, nonsteroidal anti-inflammatory drugs (NSAIDs), and herbal supplements prior to surgery. Additionally, there is a more heterogenous discussion the utility of preoperative autologous …


Mobile Ka-Band Polarimetric Doppler Radar Observations Of Wildfire Smoke Plumes, Taylor Brianna Aydell Jan 2020

Mobile Ka-Band Polarimetric Doppler Radar Observations Of Wildfire Smoke Plumes, Taylor Brianna Aydell

Master's Theses

Remote sensing techniques have been more recently used to study and track wildfire smoke plume structure and evolution; however, knowledge gaps remain due to the limited availability of observational datasets aimed at understanding the fine-scale fire-atmosphere interactions and plume microphysics. In this study, we present a new mobile millimeter-wave (Ka-band) Doppler radar system acquired to sample the fine-scale kinematics and microphysical properties of active wildfire smoke plumes from both wildfires and large prescribed fires. Four field deployments were conducted in the fall of 2019 during two wildfires in California and one prescribed burn in Utah. An additional dataset of precipitation …


Incorporating A Canopy Parameterization Within A Coupled Fire-Atmosphere Model To Improve A Smoke Simulation For A Prescribed Burn, Derek V. Mallia, Adam K. Kochanski, Shawn P. Urbanski, Jan Mandel, Angel Farguell, Steven K. Krueger Jan 2020

Incorporating A Canopy Parameterization Within A Coupled Fire-Atmosphere Model To Improve A Smoke Simulation For A Prescribed Burn, Derek V. Mallia, Adam K. Kochanski, Shawn P. Urbanski, Jan Mandel, Angel Farguell, Steven K. Krueger

Faculty Research, Scholarly, and Creative Activity

Forecasting fire growth, plume rise and smoke impacts on air quality remains a challenging task. Wildland fires dynamically interact with the atmosphere, which can impact fire behavior, plume rises, and smoke dispersion. For understory fires, the fire propagation is driven by winds attenuated by the forest canopy. However, most numerical weather prediction models providing meteorological forcing for fire models are unable to resolve canopy winds. In this study, an improved canopy model parameterization was implemented within a coupled fire-atmosphere model (WRF-SFIRE) to simulate a prescribed burn within a forested plot. Simulations with and without a canopy wind model were generated …


Racial Purges, Robert L. Tsai Jan 2020

Racial Purges, Robert L. Tsai

Faculty Scholarship

In a two-year period, 1885-86, over 168 communities in America forcibly expelled Chinese residents from their midst. This essay, inspired by historian Beth Lew-Williams's book, THE CHINESE MUST GO, investigates the nineteenth-century purges of Chinese residents that occurred throughout the American west. I make three arguments. First, these acts of racial and political terror complicate our understanding of racial violence in America. Many of the actions were denounced, but they were also surprisingly effective in forcing business and political leaders to support the indefinite suspension of Chinese migration. Perpetrators faced almost no legal repercussions, and unlike for freed persons, racial …


Validation Of Microrna Biomarkers For Alzheimer’S Disease In Human Cerebrospinal Fluid, Jack T. Wiedrick, Jay I. Phillips, Theresa A. Lusardi, Trevor J. Mcfarland, Babbet Lind, Ursula K. Sandau, Christina A. Harrington, Jodi A. Lapidusa, Multiple Additional Authors Jan 2020

Validation Of Microrna Biomarkers For Alzheimer’S Disease In Human Cerebrospinal Fluid, Jack T. Wiedrick, Jay I. Phillips, Theresa A. Lusardi, Trevor J. Mcfarland, Babbet Lind, Ursula K. Sandau, Christina A. Harrington, Jodi A. Lapidusa, Multiple Additional Authors

OHSU-PSU School of Public Health Faculty Publications and Presentations

We previously discovered microRNAs (miRNAs) in cerebrospinal fluid (CSF) that differentiate Alzheimer’s disease (AD) patients from Controls. Here we examined the performance of 37 candidate AD miRNA biomarkers in a new and independent cohort of CSF from 47 AD patients and 71 Controls on custom TaqMan arrays. We employed a consensus ranking approach to provide an overall priority score for each miRNA, then used multimarker models to assess the relative contributions of the top-ranking miRNAs to differentiate AD from Controls. We assessed classification performance of the top-ranking miRNAs when combined with apolipoprotein E4 (APOE4) genotype status or CSF amyloid-β42 (Aβ42):total …


Analysis Of Covid-19 Transmission: Low Risk Of Presymptomatic Spread?, Mark K. Slifka, William B. Messer, Ian J. Amanna Jan 2020

Analysis Of Covid-19 Transmission: Low Risk Of Presymptomatic Spread?, Mark K. Slifka, William B. Messer, Ian J. Amanna

OHSU-PSU School of Public Health Faculty Publications and Presentations

More than 6 million confirmed cases of COVID-19 (coronavirus disease 2019) have been identified worldwide and a number of case reports1-5 have indicated that COVID-19 has the potential to be transmitted prior to disease onset. Studies have also shown that infectious virus can be isolated from presymptomatic COVID-19 cases6 and although it is unknown what level of infectious virus is needed to confer efficient transmission potential, detection of infectious virus in the upper respiratory tract indicates that presymptomatic transmission of COVID-19 is plausible. Fear of asymptomatic and presymptomatic transmission of COVID-19 has led to considerable concern among public health policy …


Screening For Unhealthy Drug Use: Updated Evidence Report And Systematic Review For The Us Preventive Services Task Force, Carrie D. Patnode, Leslie A. Perdue, Megan Rushkin, Tracy Dana, Ian Blazina, Christina Bougatsos, Sara Grusing, Elizabeth A. O'Connor, Rongwei Fu, Roger Chou Jan 2020

Screening For Unhealthy Drug Use: Updated Evidence Report And Systematic Review For The Us Preventive Services Task Force, Carrie D. Patnode, Leslie A. Perdue, Megan Rushkin, Tracy Dana, Ian Blazina, Christina Bougatsos, Sara Grusing, Elizabeth A. O'Connor, Rongwei Fu, Roger Chou

OHSU-PSU School of Public Health Faculty Publications and Presentations

IMPORTANCE

Illicit drug use is among the most common causes of preventable morbidity and mortality in the US.

OBJECTIVE

To systematically review the literature on screening and interventions for drug use to inform the US Preventive Services Task Force.

DATA SOURCES MEDLINE, PubMed, PsycINFO, Embase, and Cochrane Central Register of Controlled Trials through September 18, 2018; literature surveillance through September 21, 2019. STUDY SELECTION Test accuracy studies to detect drug misuse and randomized clinical trials of screening and interventions to reduce drug use. DATA EXTRACTION AND SYNTHESIS Critical appraisal and data abstraction by 2 reviewers and random-effects meta-analyses. MAIN OUTCOMES …