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Articles 211 - 212 of 212
Full-Text Articles in Entire DC Network
Specimens Of Opportunity Reveal Novel Information On The Sowerby's Beaked Whale (Mesoplodon Bidens), Kerri Jean Smith
Specimens Of Opportunity Reveal Novel Information On The Sowerby's Beaked Whale (Mesoplodon Bidens), Kerri Jean Smith
Open Access Theses & Dissertations
Conservation science requires quickly acquiring information and taking action in order to protect species at risk of extinction. Elusive wildlife, however, present challenges to effective conservation measures because it is often difficult to collect enough data on these species to recognize their conservation needs and implement management plans. As a result, researchers must identify alternative means of gathering sufficient data on these species. Specimens of opportunity, such as museum specimens, provide a way to improve knowledge on these species, and these specimens have already proven valuable by increasing information on biodiversity, habitat and range, and population structure in many species. …
Non-Uniformity Of Projection Distributions Attenuates Resolution In Cryo-Em, Philip R Baldwin, Dmitry Lyumkis
Non-Uniformity Of Projection Distributions Attenuates Resolution In Cryo-Em, Philip R Baldwin, Dmitry Lyumkis
Faculty, Staff and Students Publications
Virtually all single-particle cryo-EM experiments currently suffer from specimen adherence to the air-water interface, leading to a non-uniform distribution in the set of projection views. Whereas it is well accepted that uniform projection distributions can lead to high-resolution reconstructions, non-uniform (anisotropic) distributions can negatively affect map quality, elongate structural features, and in some cases, prohibit interpretation altogether. Although some consequences of non-uniform sampling have been described qualitatively, we know little about how sampling quantitatively affects resolution in cryo-EM. Here, we show how inhomogeneity in any projection distribution scheme attenuates the global Fourier Shell Correlation (FSC) in relation to the number …