Digital Commons Network^™

Parkinson's Disease: Unanticipated Sequela Of An Attempted Suicide, Thomas Hammond

All Publications

Studies exploring the association between pesticide exposure and Parkinson's disease (PD) are largely limited to rural populations with occupational exposure. We could find no literature regarding PD occurring after ingestion of a pesticide. We present a case from our clinic of a man who developed PD following ingestion of a liquid pesticide during a suicide attempt. PD was diagnosed, and the patient's symptoms improved following initiation of carbidopa/levodopa. This case illustrates the potential role of ingested pesticide exposure in provoking and accelerating the manifestations of PD.

Keywords: basal ganglia; kratom; mptp; parkinson' s disease; pesticide.

The Anti-Diabetic Potential Of The African Adansonia Digitata L. Plant Extract, Marwa Tawfik Badawy

Theses and Dissertations

Diabetes Mellitus (DM) is a severe chronic disease affecting a large population worldwide. The Middle Eastern region has been gifted with lots of native medicinal plants. However, there is less information on development of these medicinal plants into nutraceuticals for modulating specific diseases such as diabetes of common occurrence regionally. Towards this end, there is a crucial need to investigate other types of treatments to modulate diabetes. This study is conducted to fill in this gap by investigating medicinal plant used as folk medicine, which is Baobab (Adansonia digitata L.). This study is performed in two phases: in-vitro and in-vivo. …

Climate Change And Community Health, Parasto Baghae Pour

Climate Change and Public Health Preparedness

No abstract provided.

Ethical Branding, Lane Gibbons

Marriott Student Review

In this article, BYU senior Lane Gibbons outlines the details of ethical branding and emphasizes the importance of corporate social responsibility in the modern era.

Liberalism Versus Fundamentalism: The Ideological Conflict Between Tocqueville And Qtub, Mary Catherine E. Morris

Liberty University Journal of Statesmanship & Public Policy

This paper seeks to conclude whether Qtub has successfully discredited the values supported by Tocqueville to draw more Muslims to support an increased role of religion in society and influence the majority of Muslims to conduct violent jihad. It is hypothesized that Muslims agree with Qtub that Islam must be increasingly influential in society, but the majority do not seek to increase its role through, or for the purposes of, violent jihad. Differing in their views on freedom and liberty, freedom of religion and separation of church and state, and man-made laws but agreeing on the negative effects of materialism, …

De Libero Conscientia: Martin Luther’S Rediscovery Of Liberty Of Conscience And Its Synthesis Of The Ancients And The Influence Of The Moderns, Bessie S. Blackburn

Liberty University Journal of Statesmanship & Public Policy

One fateful day on March 26, 1521, a lowly Augustinian monk was cited to appear before the Diet of Worms.[1] His habit trailed behind him as he braced for the questioning. He was firm, yet troubled. He boldly proclaimed: “If I am not convinced by proofs from Scripture, or clear theological reasons, I remain convinced by the passages which I have quoted from Scripture, and my conscience is held captive by the Word of God. I cannot and will not retract, for it is neither prudent nor right to go against one’s conscience. So help me God, …

Alternate Warfare: The Unseen Weapons Of Mass Destruction, Elyse Keener

Liberty University Journal of Statesmanship & Public Policy

Biological warfare is a national security concern that transcends centuries. In the current international climate, biowarfare is of particular interest due to the COVID-19 pandemic. This article seeks to follow historical cases of biological warfare and international response to these cases in order to understand the implications of COVID-19, if it were to be weaponized. Also covered is the current capabilities that Russia, China, and Iran are assessed to possess.

Statement Of World Aquatic Scientific Societies On The Need To Take Urgent Action Against Human-Caused Climate Change, Based On Scientific Evidence [Dear Colleague Letter], Scott A. Bonar, Brian R. Murphy, Leanne H. Roulson, Jesse T. Trushenski, Douglas J. Austen, Michael Edward Douglas

United States Fish and Wildlife Service: Publications

Dear Colleague Letter from the American Fisheries Society to fellow scientific societies, July 25, 2020, about the urgent need for responsive collective action to mitigate impending radical climate change. Includes the Statement of World Aquatic Scientific Societies on the Need to Take Urgent Action Against Human-Caused Climate Change, Based on Scientific Evidence, emphasizing the importance of aquatic ecosystems. Includes extensive citations and notes.

"Water is the most important natural resource on Earth as it is vital for life. Aquatic ecosystems, freshwater or marine, provide multiple benefits to human society, such as provisioning of oxygen, food, drinking water, genetic resources; regulation …

Drawn To Peace: Comics As Multimodal Narratives In Peace And Conflict Education, Laurence Stacey

Doctor of International Conflict Management Dissertations

Comics, a type of multimodal narrative, have historically been used as platforms for political discourse. Through a combination of visual, verbal, and spatial devices, comics often explore issues of peace, conflict, and justice “from below,” in ways that reveal the complexities of narrative and identity. In doing so, they have the potential to interrogate grand narratives that often go undisrupted. Humanities scholars have long recognized the value of literary and visual arts in preparing students to engage the salient themes of peace education. However, the medium of comics remains undertheorized in that field, despite the increasing popularity of comics as …

A Mother For Choco, Kiana Diggs

Diverse Families Bookshelf Lesson Plans and Activities

No abstract provided.

Transcriptional Profiling Reveals Altered Biological Characteristics Of Chorionic Stem Cells From Women With Gestational Diabetes, Liyun Chen, Chung-Teng Wang, Nicholas R Forsyth, Pensee Wu

Open Access Publications

BACKGROUND: Gestational diabetes (GDM) is a common complication of pregnancy. The impact of pregnancy complications on placental function suggests that extraembryonic stem cells in the placenta may also be affected during pregnancy. Neonatal tissue-derived stem cells, with the advantages of their differentiation capacity and non-invasive isolation processes, have been proposed as a promising therapeutic avenue for GDM management through potential cell therapy approaches. However, the influence of GDM on autologous stem cells remains unclear. Thus, studies that provide comprehensive understanding of stem cells isolated from women with GDM are essential to guide future clinical applications.

METHODS: Human chorionic membrane-derived stem …

A Panorama Of Human-Animal Interactions Research: Bibliometric Analysis Of Hai Articles 1982-2018, Jane Kinkus Yatcilla

Libraries Faculty and Staff Scholarship and Research

What can we know about human-animal interactions (HAI) research by looking at information about its research articles, such as publication information, text of abstracts or author keywords, or citation patterns? Bibliometric analysis, the quantification of information about published articles, is a tool we can use to gain a perspective of the status of research in a particular field. In this study, information about four decades of HAI research publications was obtained from the multidisciplinary research database Web of Science Core Collection, and analyzed to look for informative patterns about this body of research using Microsoft Excel and VantagePoint text …

Effect Of Choline Forms And Gut Microbiota Composition On Trimethylamine-N-Oxide Response In Healthy Men, Clara E. Cho, Niklas D. J. Aardema, Madison L. Bunnell, Deanna P. Larson, Sheryl Aguilar, Janet R. Bergeson, Olga V. Malysheva, Marie A. Caudill, Machael Lefevre

Nutrition, Dietetics, and Food Sciences Faculty Publications

Background: Trimethylamine-N-oxide (TMAO), a choline-derived gut microbiota-dependent metabolite, is a newly recognized risk marker for cardiovascular disease. We sought to determine: (1) TMAO response to meals containing free versus lipid-soluble choline and (2) effects of gut microbiome on TMAO response. Methods: In a randomized, controlled, double-blinded, crossover study, healthy men (n = 37) were provided meals containing 600 mg choline either as choline bitartrate or phosphatidylcholine, or no choline control. Results: Choline bitartrate yielded three-times greater plasma TMAO AUC (p = 0.01) and 2.5-times greater urinary TMAO change from baseline (p = 0.01) compared to no choline and phosphatidylcholine. Gut …

Supplemental Online Learning Tools (Solts) To Support Deaf And Hard Of Hearing Students In Introductory Statistics Courses, Jacqueline Mcclive, Keith Mousley, Carol E. Marchetti, David Simkins, Gary Blatto-Vallee, Jane Jackson, Sue Foster

Journal of Science Education for Students with Disabilities

Research in most Science, Technology, Engineering, and Mathematics (STEM) disciplines uses statistical methods. Thus as students develop into research scientists, introductory statistics serves as a gateway course. If students struggle to incorporate statistics into their knowledge base, they may be effectively kept from careers that rely on statistics. DHH students learn differently and thus may lag behind their hearing counterparts in mainstream classrooms. In part, a gap in language knowledge can impede the understanding of statistics topics. What is a variable? What does it mean to have a distribution? With sign language interpreters and other support services, many mainstream instructors …

The Crisis Of Communication In The Information Age: Revisiting C.P. Snow's Two Cultures In The Era Of Fake News, Aaron Green

Irish Communication Review

The purpose of this paper is to revisit C.P. Snow’s “Two Cultures” lecture in light of the cultural dominance of information technology. The crisis of communication in the information age, whether in fake news, political polarisation or science denial, has come about because both scientific and literary cultures, in seeking a world without entropy, have inadvertently stumbled upon a world without meaning. In order to explain how this has happened, the paper first explores Snow's challenge: to describe the second law of thermodynamics. The paper then provides a description of entropy that is neutral with regard to thermodynamics and information, …

Refugees And Human Rights In French-Speaking Europe, Jacob Kang

French Summer Fellows

This paper seeks to explain the manner in which French-speaking European States, namely France, Switzerland, and Belgium, treat asylum seekers. To do so, we will first examine, the philosophical underpinnings of European conceptions of the state, of personhood, and of human rights. In doing so, we move to understand cultural attitudes towards asylum seekers through European philosophers such as Rousseau and Kant. The second aspect, the legal aspect, will explain the manner through which the aforementioned philosophies are reflected through governance in each of the states. Finally, we will examine the demographic profiles of the refugees and perform an outcomes …

Healthy Eating Patterns, Jamie Baum

Diet, Food, Exercise, and Nutrition (D-FEND)

Focusing on what is an eating pattern and how to understand and incorporate a healthy eating pattern into everyday life.

Environmental Cues And Fungi Morphology, Paige Camp, Kirsten Treptow, Hailey Goodwin, Maya Leon, Anita Coleman, Michael Watters, Patrice Bouyer, Julie Peller

Summer Interdisciplinary Research Symposium

Candida albicans, a symbiotic yeast in the human gut, and Neurospora crassa, a filamentous bread mold, are distinct in habitat, morphology, and behavior. However, both fungi are equally susceptible to the ongoing flow of stimuli present within the environment. The objective of our research is to understand how different fungi respond to specific cues found within or outside their natural environment. Four stimuli were tested on C. albicans: estradiol (E2), media morphology, and irradiated and non-radiated plastic microfibers. Three stimuli were tested on N. crassa: plastic non-radiated microfibers, simulated microgravity, and cold shock. C. albicans was …

Epidemiological Study Of Trichosporon Asahii Infections Over The Past 23 Years, Haitao Li, Meihong Guo, Congmin Wang, Yibo Li, Anne Marie Fernandez, Thomas N Ferraro, Rongya Yang, Yong Chen

College of Science & Mathematics Departmental Research

Trichosporon is a yeast-like basidiomycete, a conditional pathogenic fungus that is rare in the clinic but often causes fatal infections in immunocompromised individuals. Trichosporon asahii is the most common pathogenic fungus in this genus and the occurrence of infections has dramatically increased in recent years. Here, we report a systematic literature review detailing 140 cases of T. asahii infection reported during the past 23 years. Statistical analysis shows that T. asahii infections were most frequently reported within immunodeficient or immunocompromised patients commonly with blood diseases. Antibiotic use, invasive medical equipment and chemotherapy were the leading risk factors for acquiring infection. …

Protein And Polysaccharide-Based Fiber Materials Generated From Ionic Liquids: A Review., Christopher R Gough, Ashley Rivera-Galletti, Darrel A Cowan, David Salas-De La Cruz, Xiao Hu

College of Science & Mathematics Departmental Research

Natural biomacromolecules such as structural proteins and polysaccharides are composed of the basic building blocks of life: amino acids and carbohydrates. Understanding their molecular structure, self-assembly and interaction in solvents such as ionic liquids (ILs) is critical for unleashing a flora of new materials, revolutionizing the way we fabricate multi-structural and multi-functional systems with tunable physicochemical properties. Ionic liquids are superior to organic solvents because they do not produce unwanted by-products and are considered green substitutes because of their reusability. In addition, they will significantly improve the miscibility of biopolymers with other materials while maintaining the mechanical properties of the …

Assessing The Environmental Impacts Of Urbanization In Siddharthanagar, Nepal, Bishal Raj Khanal

Economics ETDs

Rapid and haphazard infrastructural expansion often contributes to large negative externalities in cities. Environmental problems like air pollution and degradation of quality-of-life elements in an urban settlement are attributed to urban sprawl. Evidence based planning tools need to be developed which can help manage the rapid urbanization that is taking place in the developing world. In this context, we examine the relationship between health outcomes and the different spatial- temporal aspects of an urban-built environment in Siddharthanagar Metropolitan City which is a major settlement in southwestern Nepal. We attempt to identify the aspects of built environment which are closely associated …

Interleukin-22 Inhibits Respiratory Syncytial Virus Production By Blocking Virus-Mediated Subversion Of Cellular Autophagy, Sudipta Das, Claudette St Croix, Misty Good, Jie Chen, Jinming Zhao, Sanmei Hu, Mark Ross, Michael M Myerburg, Joseph M Pilewski, John Williams, Sally E Wenzel, Jay K Kolls, Anuradha Ray, Prabir Ray

Open Access Publications

Respiratory syncytial virus (RSV) infection can cause severe bronchiolitis in infants requiring hospitalization, whereas the elderly and immunocompromised are prone to RSV-induced pneumonia. RSV primarily infects lung epithelial cells. Given that no vaccine against RSV is currently available, we tested the ability of the epithelial-barrier protective cytokine interleukin-22 (IL-22) to control RSV production. When used in a therapeutic modality, IL-22 efficiently blunted RSV production from infected human airway and alveolar epithelial cells and IL-22 administration drastically reduced virus titer in the lungs of infected newborn mice. RSV infection resulted in increased expression of LC3B, a key component of the cellular …

Overcoming Sibling Rivalry In Families, Rylie Mcbride

Family Perspectives

No abstract provided.

Connection And Contribution Practice Guide, Kate Noble, Jen Jackson, Pru Mitchell

Early Childhood Education

This Practice Guide supports early childhood professionals to extend their thinking about connection, which involves orientation, curiosity and participation, and about contribution, which involves decision-making, negotiation and responsibility.

Application Of Enzymes In Regioselective And Stereoselective Organic Reactions, Ruipu Mu, Zhaoshuai Wang, Max C. Wamsley, Colbee N. Duke, Payton H. Lii, Sarah E. Epley, London C. Todd, Patty J. Roberts

Pharmaceutical Sciences Faculty Publications

Nowadays, biocatalysts have received much more attention in chemistry regarding their potential to enable high efficiency, high yield, and eco-friendly processes for a myriad of applications. Nature’s vast repository of catalysts has inspired synthetic chemists. Furthermore, the revolutionary technologies in bioengineering have provided the fast discovery and evolution of enzymes that empower chemical synthesis. This article attempts to deliver a comprehensive overview of the last two decades of investigation into enzymatic reactions and highlights the effective performance progress of bio-enzymes exploited in organic synthesis. Based on the types of enzymatic reactions and enzyme commission (E.C.) numbers, the enzymes discussed in …

The Lives, Lore, And Literature Of Cranes: A Catechism For Crane Lovers, Paul A. Johnsgard, Thomas D. Mangelsen

Zea E-Books Collection

This book provides basic information on cranes that should be of interest and importance to crane-loving birders (“craniacs”) as well as to ornithologists and wildlife managers. Primary consideration is given to the sandhill and whooping cranes, but all 13 of the Old World cranes are also discussed. Special consideration is given to the relative abundance and conservation status of all of the world’s species, of which nearly half are declining and a few are in real danger of long-term survival. More than 80 refuges and preserves in the United States and Canada, where the best chances of seeing cranes in …

Some Polycubes Have No Edge Zipper Unfolding, Erik D. Demaine, Martin L. Demaine, David Eppstein, Joseph O'Rourke

Computer Science: Faculty Publications

It is unknown whether every polycube (polyhedron constructed by gluing cubes face-to-face) has an edge unfolding, that is, cuts along edges of the cubes that unfolds the polycube to a single nonoverlapping polygon in the plane. Here we construct polycubes that have no edge zipper unfolding where the cut edges are further restricted to form a path.

Assessment Of Dehydration As A Commercial-Scale Food Waste Valorization Strategy, Jon T. Schroeder, Ava L. Labuzetta, Thomas A. Trabold

Articles

Using a commercially available dehydration unit, this study aimed to valorize various food waste streams from different sources in the Rochester, New York area. Dehydration of the food waste collected for the study helped reduce the weight of the feedstock by 70–90%, as the incoming waste streams were relatively wet. The output was materially characterized against end uses such as cattle feed, fish feed, and compost. The results demonstrated that, other than fertilizer, the remaining five end uses (compost, fish feed, cattle feed, pyrolysis, and pelletized fuel) were potentially compatible with varying waste feedstocks based on the parameters analyzed. Fish …

Spring/Summer 2020: A Short Course In Media Effects, St. Norbert College

St. Norbert College Magazine 2019-2023

Miss hitting the books? In this new occasional feature, your St. Norbert education continues as we profile a course or lecture taught by our own faculty. (And this time, there’s no final!)

Microrna-29 Family: A Positive Regulator Of Osteoclastogenesis, Henry Hrdlicka

Doctoral Dissertations

Osteoclasts are large multinucleated bone cells of the myeloid lineage. Osteoclasts secrete proteases and create an acidic environment, causing bone resorption. Osteoclast differentiation, driven by MCSF and RANKL, is tightly regulated by numerous factors, including microRNAs (miRNAs, miRs). miRNAs are short non-coding RNAs that post-transcriptionally regulate gene expression by binding to complementary mRNA sequences, leading to mRNA degradation or destabilization. The aim of these studies was to investigate the function of the miRNA-29-3p family in osteoclasts both in vivo and in vitro.

We generated mice which globally express a miR-29-3p tough decoy which competitively inhibits miR-29-3p activity. The examination …