Digital Commons Network^™

“When I Breastfeed, It Feels As If My Soul Leaves The Body”: Maternal Capabilities For Healthy Child Growth In Rural Southeastern Tanzania, Zaina Mchome, Sepideh Yousefzadeh, Ajay Bailey, Hinke Haisma

Open Access archive

The burden of childhood stunting in Tanzania is persistently high, even in high food-producing regions. This calls for a paradigm shift in Child Growth Monitoring (CGM) to a multi-dimensional approach that also includes the contextual information of an individual child and her/his caregivers. To contribute to the further development of CGM to reflect local contexts, we engaged the Capability Framework for Child Growth (CFCG) to identify maternal capabilities for ensuring healthy child growth. Ethnographic fieldwork was conducted in Southeastern Tanzania using in-depth interviews, key informant interviews, participant observation, and focus group discussions with caregivers for under-fives. Three maternal capabilities for …

Leptospiral Uveitis In Coastal Karnataka: A Case Report, Yogish Kamath, Alisha Rizvi, T. Ravikumar, Shashidhar Vishwanath

Open Access archive

We report a case of a young male from Udupi, Karnataka, presenting with features of bilateral non-granulomatous anterior uveitis with mild vitritis. There was a history of fever and myalgia a month before ocular features, which was partially treated. He also gave a history of being actively involved in the flood relief work in the district, before the onset of fever. This prompted an evaluation of leptospirosis, which came positive. The possibility of leptospira uveitis needs to be considered, especially in cases of non-granulomatous uveitis after floods in areas endemic for leptospirosis, which may otherwise be wrongly labeled idiopathic.

Pestilence And Other Calamities In Civilizational Theory: Sorokin, Mcneill, Diamond, And Beyond, Vlad Alalykin-Izvekov

Comparative Civilizations Review

This paper analyses the phenomenon of pestilence through paradigmatic and methodological lenses of several outstanding social scholars, including Pitirim A. Sorokin, William H. McNeill, and Jared M. Diamond. All three thinkers have advanced original, fundamental, and revolutionary paradigms regarding the profound role which infectious diseases played, are playing, and will continue to play in world history and culture. The phenomenon of pestilence is studied in the context of other major calamities. The relevant historic, as well as contemporary macro-level and long-term sociocultural research, is reviewed. The author advances a number of original concepts, as well as makes relevant projections into …

Montana Voices Amplified: A Parent’S Perspective: Navigating Face Coverings, Elizabeth Cummings, University Of Montana Rural Institute

Independent Living and Community Participation

Everyone is talking about masks. As the research on their effectiveness as a tool to battle the COVID-19 pandemic grows, so does the list of places requiring them. Montana recently joined the states with a mask mandate, perhaps raising questions for many families with an individual with a disability. I am a parent of a child with complex special needs and have had these thoughts going through my mind over the last months as well. Could my son Charlie ever wear a mask? How would I teach him? What does the new normal mean for my unique family?

Briefs: Open Mic

Reimaginings

SCPS alumni answer the Vincentian question, "What Must Be Done?" Their answers include a reckoning with racism in the United States, mutual respect, aid for our poorest neighborhoods and world cooperation.

The Art Of Opacity: Guy De Cointet In L.A., Media Farzin

Dissertations, Theses, and Capstone Projects

This dissertation provides the first detailed study of the work of French artist Guy de Cointet (1934–1983), specifically the books, objects, and performances he produced in Los Angeles between 1971 and 1983. Much of this work mined pop-cultural sources—genre fiction, magazine advertising, and television serials—for texts, which he reused in deliberately obfuscated ways: in pseudonymous publications written in code or invented languages, as well as in sigil-like paintings that doubled as props for performances in which actors delivered contradictory interpretations of the encoded objects. I argue that Cointet’s appropriations of the visual and narrative logics of postwar culture provide a …

Energy Metabolism In Jersey Cows: Improving Our Understanding Of Energy Requirements And Utilization, Dennis Morris

Department of Animal Science: Dissertations, Theses, and Student Research

Energy is the most limiting nutrient for high producing lactating dairy cows and improving our understand of factors affecting energy supply should improve our ability to estimate net energy of lactation (NE_L), milk production, and tissue accretion. To achieve this object, firstly, three experiments were completed to determine 1) maintenance energy requirements; 2) factors affecting heat production; and 3) the relationship between urinary N and energy excretion. Three additional experiments using lactating Jersey cows were completed to evaluate energy utilization of diets varying in 1) supply of Lys and His; 2) fatty acids (FA) and …

Frequency Of Intraoperative Hypotension After The Induction Of Anesthesia In Hypertensive Patients With Preoperative Angiotensin-Converting Enzyme Inhibitors, Fahad Salim, Fazal Hameed Khan, Muhammad Nasir, Rashid Ali, Ayesha Iqbal, Amir Raza

Department of Anaesthesia

Introduction: The renin-angiotensin-aldosterone system (RAAS) is an important target in the treatment of hypertension. Angiotensin-converting enzyme (ACE) inhibitors block the conversion of angiotensin I to angiotensin II. ACE inhibitors not only treat hypertension but also decrease morbidity and mortality in heart failure patients and in patients with acute myocardial infarction. The discontinuation of ACE inhibitors before the surgery is still controversial. To assess the current magnitude of the problem in our population, we aimed to conduct this study, which evaluated the frequency of intraoperative hypotension after the induction of anesthesia in controlled hypertensive patients with preoperative ACE inhibitors.
Material and …

Occurrence Of Extended Spectrum Beta-Lactamase Gram-Negative Bacteria From Non-Clinical Sources In Dubai, United Arab Emirates, Munawwar A. Khan, Nicola E. Thurgood, Sultan M. Faheem, Naushad Rais, Mohammad Z. Ansari, Sultan M. Kaleem, Shams T. Khan

All Works

© 2020 by the authors. Extended-spectrum beta-lactamase (ESBL) producing bacteria of the Enterobacteriaceae family are a significant threat to public health, posing a challenge for health authorities worldwide. In the UAE, very little information is available about ESBL producing bacteria from non-clinical sources. In this study, 206 pure cultures belonging to the Enterobacteriaceae family were isolated from food and wastewater sources in Dubai, UAE. All the isolates were tested against third-generation cephalosporin antibiotics by the disc diffusion method and screened on ESBL chromogenic agar. Among all isolates (n = 86), 41.7% were potential ESBL producers belonging to E. coli, Klebsiella, …

Quantification Of Lactoyl-Coa (Lactyl-Coa) By Liquid Chromatography Mass Spectrometry In Mammalian Cells And Tissues., Erika L Varner, Sophie Trefely, David Bartee, Eliana Von Krusenstiern, Luke Izzo, Carmen Bekeova, Roddy S O'Connor, Erin L Seifert, Kathryn E Wellen, Jordan L Meier, Nathaniel W Snyder

Department of Pathology, Anatomy, and Cell Biology Faculty Papers

Lysine lactoylation is a recently described protein post-translational modification (PTM). However, the biochemical pathways responsible for this acylation remain unclear. Two metabolite-dependent mechanisms have been proposed: enzymatic histone lysine lactoylation derived from lactoyl-coenzyme A (lactoyl-CoA, also termed lactyl-CoA), and non-enzymatic lysine lactoylation resulting from acyl-transfer via lactoyl-glutathione. While the former has precedent in the form of enzyme-catalysed lysine acylation, the lactoyl-CoA metabolite has not been previously quantified in mammalian systems. Here, we use liquid chromatography-high-resolution mass spectrometry (LC-HRMS) together with a synthetic standard to detect and validate the presence of lactoyl-CoA in cell and tissue samples. Conducting a retrospective analysis …

Incidence And Molecular Characterization Of Fungi And Yeast Isolated From Cultured Catfish And Nile Tilapia., Ola Hashem, Viola Zaki, Radwia Adawy

Mansoura Veterinary Medical Journal

Objective: To study the incidence and seasonal dynamics of different fungi affecting freshwater fishes in Lake Manzala as well as molecular identification of the isolated fungi. Animals: 300 Nile tilapia (Oreochromis niloticus) and 300 catfish (Clarias gariepinus). Design: Descriptive study. Procedures: Random samples of Oreochromis niloticus (O. niloticus) and Clarias gariepinus (C. gariepinus) were collected from Manzala fish farms. Clinical and postmortem examination of fish was applied. Isolation and identification of different fungi were performed by conventional methods.Furthermore, the molecular characterization of isolated fungi was carried out. Results: C. gariepinus had a higher rate of infection with different fungal species …

Protective Effect Of Nannochloropsis Oculata Against Mercuric-Induced Histopathological Alterations In The Kidney Of Nile Tilapia., Alzahraa Mamdouh, Eman Zahran, Fatma Mohamed, Viola Zaki

Mansoura Veterinary Medical Journal

Objective: The present study was designed to evaluate the toxic effect of sublethal concentration of mercuric chloride (0.3 mg/L HgCl2) on histopathological lesions in the kidney of Nile tilapia (O. niloticus) and the protective effect of microalgae, Nannochloropsis oculata (N. oculata) against the induced tissue alterations for 3 weeks. Design: Randomized controlled study Animals: Nile tilapia Procedures: Fish were randomly assigned to 4 groups, group1: control (basal diet), group 2 (Hg/ exposed to HgCl2 at a dose of 0.3 mg/L (1/4 of LC50), and fed basal diet), group 3: (Hg+N5, similar to group2, but fed diet supplemented with N. oculata …

Effect Of Dietary Probiotic, Antibiotic Or Combination On Broiler Performance, Cecum Microbial Population And Ileal Development, Ahmed Elbaz, Said El-Sheikh

Mansoura Veterinary Medical Journal

Objective: To investigate the effect of antibiotics and/or probiotics on performance, some serum metabolites, cecum microflora composition, and ileum histomorphology in broilers under the Egyptian conditions. Design: Randomized controlled experimental study. Animals: Two hundred forty 1-day-old Ross (308) chicks were reared till 35 days of age. Procedures: The birds were randomly allocated into four main groups: a control diet without additives (CON); probiotic (Lactobacillus acidophilus) supplemented diet (PRO); antibiotic (Avilamycin) supplemented diet (ANT) and a mix group (AP) that received antibiotic in the diet form 1 to 4 days of age and treated during the rest of the experimental period …

The Protective Effect Of Sulforaphane In Rats Fed On High Cholesterol High Fructose Diets, Wael El-Shahat, Mohamed Eladl, Mohamed Hamed, El-Saedy Youssef

Mansoura Veterinary Medical Journal

Objective: To evaluate the protective role of sulforaphane in rats exposed to high cholesterol and high fructose diet. Design: Randomized experimental study. Animals: Twenty-four male Sprague Dawley rats. Procedures: Rats were allocated in groups of six animals to one of four groups. The first group was kept as a control group in which rats were fed on a basal diet for 15 weeks (Control), while in the second group (Control + SFN) rats were fed on the basal diet for 11 weeks then a sulforaphane (SFN) was given (0.5 mg/kg/day) orally for additional 4 weeks. The third group was the …

Postnatal Toxicity Of Copper Oxychloride In Lactating Female Albino Rats, Mohamed Abomosallam, Mahmoud Elalfy, Fathy Sleem

Mansoura Veterinary Medical Journal

Objective:To evaluate the postnatal toxicity of copper oxychloride (COC) in lactating female albino rats. Design:Randomized controlled experimental study. Animals: Eighteen pregnant female albino rats weight 150±10 g and 6-7 week old. Procedures: Eighteen pregnant female albino rats were divided into 3 groups treated orally with copper oxychloride 0, 73.5, 147 mg/kg (equivalent 1/20 and 1/10 of LD50) daily from first day of parturition for 21 days. Female rats and its offspring were euthanized at 21 days of treatment. The postnatal toxic effect in the neonates and dams were estimated through biochemical biomarkers as metabolic and oxidative stress biomarkers, histopathological and …

Induction Of Surgical Obstructive Cholestasis In Rats: Morphological, Biochemical And Immunohistochemical Changes, Nermeen Elsaied, Alaa Samy, Esam Mosbah, Adel Zaghloul

Mansoura Veterinary Medical Journal

Objective: To detail an easy approach for surgical induction of obstructive cholestasis in a rat model. Additionally, to assess the role of serum and tissue biomarkers for determination of the extent of cholestasis induced hepatocellular injury and to quantify the apoptotic liver cell using fluorescein-labeled Annexin V. Design: Randomized controlled experimental study. Animals: Sixty-five healthy Male Sprague- Dawley rats weighing 268.18 ± 23.3 grams. Procedures: The rats were randomly allocated into two main groups: 1) sham group (SO; n= 15) and 2) bile duct ligation group (BL; n= 50). Three SO rats and 8 BL rats were euthanized at 10, …

Ameliorative Effects Of Pergamum Harmala Seed Extract On Obese Diabetic Rats, Neveen Magdy, Mohamed Salama, Youssef Alsaedy, Gehad El-Sayed

Mansoura Veterinary Medical Journal

Objective:To explore the potential antidiabetic activity of methanolic extract of Harmal seeds in obese-diabetic rats. Design: Randomized controlled experimental study. Animals: Forty male Sprague Dawley rats. Procedures: The P. harmala seeds methanolic extract was prepared and orally administered at two doses of 150 and 250 mg/kg to two groups of streptozotocin-induced diabetic rats. Two additional control groups were used as healthy control and obese-diabetic control groups. Animals were euthanized after 8 weeks of experimental period, blood and tissue samples were collected. Liver tissue samples were used to determine antioxidant and oxidative stress markers; while those from adipose tissue were used …

Conditional Loss Of Engrailed 1/2 In Rhombic Lip-Derived Neurons Increases Intrinsic Rhythmicity And Decreases Overall Variability Of Eupneic Respiration, Angela P. Taylor

Theses and Dissertations (ETD)

Evidence for a cerebellar role during cardiopulmonary challenges has long been established, but investigation into cerebellar involvement in eupneic breathing has been inconclusive. Given the view of the cerebellum (CRB) as a temporally coordinating structure, any investigation into the CRB during respiration must evaluate rhythm and variability of the respiratory sequence. In this study, we chose an elegant model of cerebellar neuropathology, Atoh1-En1/2 CKO, where mutant animals have conditional loss of the developmental patterning gene Engrailed 1/2 in rhombic lip-lineage neurons and exhibit a proportional scaling-down of neuron number in hypoplastic lobules of the CRB. We utilized whole-body unrestrained plethysmography …

Genomic Instability And The Oncohistone H3k27m Drive Gliomagenesis In A Murine Model, Lee J. Pribyl

Theses and Dissertations (ETD)

Maintaining genome stability is crucial for human health and it is of particular importance in neural cells during early brain development. Genome maintenance occurs at two broad stages; surveillance during DNA replication and DNA damage repair in differentiating and mature cells. Neural cells are particularly sensitive to DNA strand breaks and defective DNA damage responses can result in detrimental effects on the nervous system, including cancer. Multiple DNA repair pathways play critical roles in preventing DNA damage accumulation in stem and neural progenitor cells. The mechanisms that protect progenitor genomes also suppress DNA mutations that can result in cancer. A …

Context-Specific Challenges, Opportunities, And Ethics Of Drones For Healthcare Delivery In The Eyes Of Program Managers And Field Staff: A Multi-Site Qualitative Study, Vyshnave Jeyabalan, Elysée Nouvet, Patrick Meier, Lorie Donelle Phd, Rn, Fcan

Publications

Unmanned aerial vehicles (UAVs), also known as drones, have significant potential in the healthcare field. Ethical and practical concerns, challenges, and complexities of using drones for specific and diverse healthcare purposes have been minimally explored to date. This paper aims to document and advance awareness of diverse context-specific concerns, challenges, and complexities encountered by individuals working on the front lines of drones for health. It draws on original qualitative research and data from semi-structured interviews (N = 16) with drones for health program managers and field staff in nine countries. Directed thematic analysis was used to analyze interviews and identify …

Administrative Guideline No.2: Principles For Grant And Management Of Aquaculture Leases In Coastal Waters Of Western Australia, Department Of Primary Industries And Regional Development

Fisheries Administrative Guidelines

Under s.246 of the Fish Resources Management Act 1994 (FRMA), the Minister for Fisheries (Minister) may issue guidelines for the administration or enforcement of the Act.

This Administrative Guideline (Guideline) sets out the principles and processes for granting and managing aquaculture leases; its purpose is to provide guidance to the Department of Primary Industries and Regional Development (Department) and continued certainty and transparency for the aquaculture industry, stakeholders and the community.

Personality Affects Dynamics Of An Experimental Pathogen In Little Brown Bats, Quinn M.R. Webber, Craig K.R. Willis

KIP Articles

Host behaviour can affect host–pathogen dynamics and theory predicts that certain individuals disproportionately infect conspecifics during an epidemic. Consistent individual differences in behaviour, or personality, could influence this variation with the most exploratory or sociable individuals most likely to spread pathogens. We quantified exploration and sociability in little brown bats ( Myotis lucifugus ) and then experimentally manipulated exposure to a proxy pathogen (i.e. ultraviolet (UV) fluorescent powder) to test two related hypotheses: (i) more sociable and more exploratory individuals would be more likely to transmit infections to other individuals, and (ii) more sociable and more exploratory individuals uninfected with …

Differential Diagnosis Of Apraxia Of Speech In Children And Adults: A Scoping Review, Kristen M. Allison, Claire Cordella, Jenya Iuzzini-Seigel, Jordan R. Green

Speech Pathology and Audiology Faculty Research and Publications

Purpose: Despite having distinct etiologies, acquired apraxia of speech (AOS) and childhood apraxia of speech (CAS) share the same central diagnostic challenge (i.e., isolating markers specific to an impairment in speech motor planning/ programming). The purpose of this review was to evaluate and compare the state of the evidence on approaches to differential diagnosis for AOS and CAS and to identify gaps in each literature that could provide directions for future research aimed to improve clinical diagnosis of these disorders. Method: We conducted a scoping review of literature published between 1997 and 2019, following the Preferred Reporting Items for Systematic …

Copulas In Classical Probability Sense, Ahmed Al-Adilee, Zainalabideen Abdual Samad, Samer T. A. Al-Shibley

Baghdad Science Journal

Copulas are simply equivalent structures to joint distribution functions. Then, we propose modified structures that depend on classical probability space and concepts with respect to copulas. Copulas have been presented in equivalent probability measure forms to the classical forms in order to examine any possible modern probabilistic relations. A probability of events was demonstrated as elements of copulas instead of random variables with a knowledge that each probability of an event belongs to [0,1]. Also, some probabilistic constructions have been shown within independent, and conditional probability concepts. A Bay's probability relation and its properties were discussed with respect to copulas. …

Identification Of Acinetobacter Baumannii And Determination Of Mdr And Xdr Strains, Noor Hussein Ahmad, Ghada A. Mohammad

Baghdad Science Journal

The current study focuses on the bacterium Acinetobacter baumannii due to its importance as a nosocomial infections source in addition to its increased resistance against antibiotics. Different clinical and hospital environment samples were collected, and cultured on A. baumannii selective media: Leed Acinetobacter agar and Herellea agar. A. baumannii have been identified by traditional methods, followed by confirmation using molecular identification to detect blaoxa-51 like gene which is considered a diagnostic gene since it is present in genome of all A. baumannii strains. The result was, nineteen bacterial isolates of A.baumannii were obtained, from twenty-seven suspected isolates, detection of local …

Pardoning Dogs, Sarah Schindler

Nevada Law Journal

In 1994, the Governor of New Jersey pardoned a dog. In 2017, the Governor of Maine did the same. Each of these dogs had been ordered to be euthanized after killing another dog. While the Governor of New Jersey relied on the property status of the dog in issuing her order, the Governor of Maine relied on his standard pardon power, despite the fact that the being to be pardoned was a dog rather than a human. Both of these cases generated a great deal of popular press and attention, and a few months ago, a New York state senator …

Digging Into Algorithms: Legal Ethics And Legal Access, Carla L. Reyes, Jeff Ward

Nevada Law Journal

The current discussions around algorithms, legal ethics, and expanding legal access through technological tools gravitate around two themes: (1) protection of the integrity of the legal profession and (2) a desire to ensure greater access to legal services. The hype cycle often pits the desire to protect the integrity of the legal profession against the ability to use algorithms to provide greater access to legal services, as though they are mutually exclusive. In reality, the arguments around protecting the profession from the threats posed by algorithms represent an over-fit in relation to what algorithms can actually achieve, while the visions …

Long Noncoding Rna H19x Is A Key Mediator Of Tgf-Β-Driven Fibrosi, Elena Pachera, Shervin Assassi, Gloria A Salazar, Mara Stellato, Florian Renoux, Adam Wunderlin, Przemyslaw Blyszczuk, Robert Lafyatis, Fina Kurreeman, Jeska De Vries-Bouwstra, Tobias Messemaker, Carol A Feghali-Bostwick, Gerhard Rogler, Wouter T Van Haaften, Gerard Dijkstra, Fiona Oakley, Maurizio Calcagni, Janine Schniering, Britta Maurer, Jörg Hw Distler, Gabriela Kania, Mojca Frank-Bertoncelj, Oliver Distler

Faculty, Staff and Student Publications

TGF-β is a master regulator of fibrosis, driving the differentiation of fibroblasts into apoptosis-resistant myofibroblasts and sustaining the production of extracellular matrix (ECM) components. Here, we identified the nuclear long noncoding RNA (lncRNA) H19X as a master regulator of TGF-β-driven tissue fibrosis. H19X was consistently upregulated in a wide variety of human fibrotic tissues and diseases and was strongly induced by TGF-β, particularly in fibroblasts and fibroblast-related cells. Functional experiments following H19X silencing revealed that H19X was an obligatory factor for TGF-β-induced ECM synthesis as well as differentiation and survival of ECM-producing myofibroblasts. We showed that H19X regulates DDIT4L gene …

Correlations Between Soil Redness And Soil Properties That Affect Non-Native Annual Plant Distribution In Chaparral And California Sage Scrub, Madeline Blua

Electronic Theses, Projects, and Dissertations

Non-native annual plant species have degraded California Sage Scrub and chaparral and present obstacles to shrubland restoration. Red soil patches in chaparral and California Sage Scrub of San Bernardino and Riverside counties appear to support fewer non-native annual plants than non-red soils. The purpose of this study was to confirm differences in vegetation cover between red and non-red soils in shrublands and to use soil analyses to determine possible causes. During vegetation surveys conducted in April of 2018, it was confirmed that red soil sites had lower cover of non-native plants and higher cover of native plant species than the …

Diagnosis And Management Of Childhood Sleep-Disordered Breathing: Clinical Approach, Abdullah Al-Shamrani, Adel S. Alharbi

Saudi Medical Journal

Sleep-disordered breathing (SDB) includes disorders of breathing that affect airway patency, which impair children’s sleep and lead to negative consequences. Obstructive sleep apnea, hypoventilation and upper airway resistance syndrome are common causes of morbidity and mortality in childhood. These clinical practice guidelines, intended for use by pediatricians and primary care clinicians, provide a clear recommendation for the diagnosis and management of sleep-disordered breathing, focusing on the most serious disorder, obstructive sleep apnea syndrome (OSAS). These clinical guidelines formulate clear recommendations to identify patients with suspected OSAS. Further, the manuscript will highlight the potential consequences of SBD in children, and how …