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2020

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Articles 22831 - 22860 of 24014

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Application Of An Indirect Mila Elisa For The Detection Of Mycoplasma Bovis Antibodiesin Bovine Milk, Abd Al Bar Al Farha, Nadeeka Wawegama, Farhid Hemmatzadeh, Simon Firestone, Jamie Moffat, Gholam Ali Kojouri, Ania Ahaniazari, Reza Amanollahi, Andrew Hoare, Kiro Petrovski Jan 2020

Application Of An Indirect Mila Elisa For The Detection Of Mycoplasma Bovis Antibodiesin Bovine Milk, Abd Al Bar Al Farha, Nadeeka Wawegama, Farhid Hemmatzadeh, Simon Firestone, Jamie Moffat, Gholam Ali Kojouri, Ania Ahaniazari, Reza Amanollahi, Andrew Hoare, Kiro Petrovski

Turkish Journal of Veterinary & Animal Sciences

The objective of this study was to detect Mycoplasma bovis specific antibodies using a recently reported MilA ELISA with the aim to detect M. bovis antibodies in milk. An indirect ELISA, based on a recombinant fragment of the Mycoplasma immunogenic lipase A (MilA) protein, was conducted on 291 milk samples for the detection of M. bovis antibodies. Samples were also tested with conventional Mycoplasma culture and M. bovis PCR. Samples were collected from individual cows from 2 commercial dairy herds in South Australia. Of 291 samples tested, 68 (23.4%) were detected positive for M. bovis antibodies, 150 (51.5%) were positive …

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Pathogenicity Of Aerobic Bacteria Isolated From Honeybees (Apis Mellifera) In Ordu Province, Emi̇ne Şeyma Boğ, Ömer Ertürk, Mustafa Yaman Jan 2020

Pathogenicity Of Aerobic Bacteria Isolated From Honeybees (Apis Mellifera) In Ordu Province, Emi̇ne Şeyma Boğ, Ömer Ertürk, Mustafa Yaman

Turkish Journal of Veterinary & Animal Sciences

The honeybee (Apis mellifera) is an important pollinator insect. Any pathogenic infection in this beneficial insect is undesirable. In this study, bacterial diversity in beehives was investigated to determine the potential of pathogenic bacteria in honeybees. To do this, bacterial isolations were carried out from dead and diseased adult bees collected from 9 districts in Ordu Province in Turkey.Twenty species of pathogenic bacteria, 18 of which were nonsporeforming Staphylococcus lentus, Klebsiella oxytoca, Citrobacter freundii, Leucanostoc mesenteroides ssp. cremoris, Kocuria rosea, Kocuria kristinae, Sphingomonas paucimobilis slashline, Burkholderia cepacia, Leucanostoc mesenteroides ssp. dextranicum,Hafnia alvei, Escherichia coli, Aeromonas salmonicida, Citrobacter braakii, Pantoea agglomerans, …

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‘Warming Up’ To Sustainable Procurement, Steven L. Schooner, Markus Speidel Jan 2020

‘Warming Up’ To Sustainable Procurement, Steven L. Schooner, Markus Speidel

GW Law Faculty Publications & Other Works

Procurement professionals will play a critical role in the belated but necessary effort to slow the pace of climate change. That critical, evolved role will lie in sustainable procurement, which, if effectively implemented, will dramatically alter markets and fundamentally change purchasing behaviors. To be effective, procurement professionals will need to rethink how we define our profession, assess our outcomes, and bring value to our government customers. Successfully establishing a sustainable procurement regime will require dramatic change, including, among other things, overcoming the persistent tyranny of low price, understanding and adopting lifecycle costing, considering externalities in the value proposition, and, of …

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Potential Of Raman Spectroscopy For The Analysis Of Plasma/Serum In The Liquid State: Recent Advances, Drishya Rajan Parachalil, Jennifer Mcintyre, Hugh Byrne Jan 2020

Potential Of Raman Spectroscopy For The Analysis Of Plasma/Serum In The Liquid State: Recent Advances, Drishya Rajan Parachalil, Jennifer Mcintyre, Hugh Byrne

Articles

There is compelling evidence in the literature to support the application of Raman spectroscopy for analysis of bodily fluids in their native liquid state. Naturally, the strategies described in the literature for Raman spectroscopic analysis of liquid samples have advantages and disadvantages. Herein, recent advances in the analysis of plasma/serum in the liquid state are reviewed. The potential advantages of Raman analysis in the liquid form over the commonly employed infrared absorption analysis in the dried droplet form are initially highlighted. Improvements in measurement protocols based on inverted microscopic geometries, clinically adaptable substrates, data preprocessing and analysis, and applications for …

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Full Disclosure: Family Violence And Legal Ethics Jan 2020

Full Disclosure: Family Violence And Legal Ethics

UBC Law Review

No abstract provided.

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The Effects Of Thyme Oil And Black Cumin Oil In Broiler Feeding On Growth Performance, Intestinal Histomorphology, And Cecal Volatile Fatty Acids, Özlem Durna Aydin, Gülteki̇n Yildiz Jan 2020

The Effects Of Thyme Oil And Black Cumin Oil In Broiler Feeding On Growth Performance, Intestinal Histomorphology, And Cecal Volatile Fatty Acids, Özlem Durna Aydin, Gülteki̇n Yildiz

Turkish Journal of Veterinary & Animal Sciences

The aim of the study was to investigate the effects of thyme oil and black cumin oil that are added to broiler rations at certain ratios, on performance (body weight, body weight gain, feed intake, feed conversion ratio, mortality, European Production Efficiency Factor (EPEF), histomorphological parameters of jejunum and ileum, and cecal short-chain fatty acid (SCFA) concentrations. In the study, 216 male chicks (Ross 308) were randomly divided into 4 groups of 54 chicks each. Each group was divided into 9 subgroups of 6 chicks. The chicks were fed with corn, soya bean, and full-fat soybean-based rations for 42 days. …

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Herbal Feed Additives Containing Tannins: Impact On In Vitro Fermentation And Methanemitigation From Total Mixed Ration, Manju Wadhwa, Prabh Kaur Sidhu, Mohinder Pal Singh Bakshi Jan 2020

Herbal Feed Additives Containing Tannins: Impact On In Vitro Fermentation And Methanemitigation From Total Mixed Ration, Manju Wadhwa, Prabh Kaur Sidhu, Mohinder Pal Singh Bakshi

Turkish Journal of Veterinary & Animal Sciences

Total mixed ration (TMR) containing roughage and concentrate mixture in a 65: 35 ratio on dry matter (DM) basis was supplemented with herbal feed additives [(HFAs); Acacia catechu (Katha), Areca catechu (Supari), and Acacia nilotica (Babul)] at 0-4% on DM basis to assess their impact on fermentation pattern and methane production by using in vitro gas production technique. Areca catechu had the highest (P < 0.01) concentration of condensed tannins (CTs), saponins, and vitamin C as compared to other HFAs. The net gas production (NGP), digestibility of NDF and true OM, and ME availability, partitioning factor (PF), volatile fatty acids (VFAs), and microbial biomass production were higher (P < 0.01) at 24 h as compared to t-half incubation, irrespective of type and level of HFAs supplemented. Acacia nilotica had an edge over Acacia catechu with respect to digestibility of nutrients and ME availability. VFAs production and efficiency of rumen fermentation was the highest from the Areca catechu-supplemented TMR. Irrespective of type of HFAs and incubation period, the digestibility of NDF and that of true OM were highest (P < 0.01) at the 1% level of supplementation, but depressed thereafter. Amongst HFAs-supplemented groups, VFA production and fermentation efficiency were highest at the 2% level. The results conclusively revealed that supplementing Areca catechu and Acacia nilotica at 2% of TMR (DM basis) inhibited the methane production, without affecting the fermentation pattern.

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Changes In Serum Biochemical And Lipid Profile, And Fatty Acid Composition Of Breast Meat Of Broiler Chickens Fed Supplemental Grape Seed Extract, Özlem Karadağoğlu, Tarkan Şahi̇n, Mükremi̇n Ölmez, Akin Yakan, Bülent Özsoy Jan 2020

Changes In Serum Biochemical And Lipid Profile, And Fatty Acid Composition Of Breast Meat Of Broiler Chickens Fed Supplemental Grape Seed Extract, Özlem Karadağoğlu, Tarkan Şahi̇n, Mükremi̇n Ölmez, Akin Yakan, Bülent Özsoy

Turkish Journal of Veterinary & Animal Sciences

A study was conducted to evaluate the changes in serum biochemical and lipid profile, and fatty acid composition of breast meat of broiler chickens fed supplemental grape seed extract (GSE). A total of 240 1-day-old male broiler chickens were randomly allocated to 4 groups, each consisting of 4 replicate pens having 15 birds/replicate pen. One group served as control group fed basal diets and other groups received 100, 200, and 400 ppm GSE supplemented to the basal diets. Liver weight was greater in broilers fed 200 ppm GSE compared to the other groups (P = 0.004, L = 0.024, C …

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Sheep Welfare During Transport And Slaughter In Bulgaria - Impact Of Welfare On Slaughter Carcass And Meat Quality: A Review, Nikolay Todorov Ivanov Jan 2020

Sheep Welfare During Transport And Slaughter In Bulgaria - Impact Of Welfare On Slaughter Carcass And Meat Quality: A Review, Nikolay Todorov Ivanov

Turkish Journal of Veterinary & Animal Sciences

The present work aimed to review the state of sheep welfare in Bulgaria during transportation and slaughter and to evaluate its relationship with slaughter carcass and meat quality. Over the last few years, animal welfare has become increasingly important. Normative documents related to welfare during rearing, transport, and slaughter of animals have been developed and promulgated. A major percentage of these animals are reared for meat production, but attempts to minimize stress and pain during transport and slaughter should be made. Stress reduction and pain control improve animal welfare and also impact carcass and meat quality. This overview demonstrates that …

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Salivary Cortisol Levels In Horses And Their Junior Riders During Show Jumping, Katarzyna Strzelec, Slawomir Pietrzak, Tomasz Próchniak, Iwona Janczarek, Anna Cywinska, Andrzej Bereznowski Jan 2020

Salivary Cortisol Levels In Horses And Their Junior Riders During Show Jumping, Katarzyna Strzelec, Slawomir Pietrzak, Tomasz Próchniak, Iwona Janczarek, Anna Cywinska, Andrzej Bereznowski

Turkish Journal of Veterinary & Animal Sciences

The group of 22 warm-blooded half-breed horses (6 stallions, 6 mares, and 10 geldings) and their riders (12 women and 10 men) who ended jumping competition for juniors, were selected for a study. The horses were aged from 7 to 17 years, while the riders were 15 to 18 years old. The saliva samples were collected before and after each jumping round. The cortisol concentration was determined by using an immunoassay method. The following factors were considered: horses' sex, age, and breeds, riders' sex and age as well. In riders, significant correlation was found in the group of younger juniors …

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The Effects Of Supplemental Niacin And Methionine On Serum Glucose, Betahydroxybutyric Acid, And Non-Esterified Fatty Acid Levels During Late Gestation And Early Postpartum Period In Damascus Dairy Goat, Mustafa Kemal Saribay, Ayşe Merve Köse, Bülent Özsoy, Umair Ahsan, Ece Koldaş Ürer, Serkan İrfan Köse, Gökhan Doğruer Jan 2020

The Effects Of Supplemental Niacin And Methionine On Serum Glucose, Betahydroxybutyric Acid, And Non-Esterified Fatty Acid Levels During Late Gestation And Early Postpartum Period In Damascus Dairy Goat, Mustafa Kemal Saribay, Ayşe Merve Köse, Bülent Özsoy, Umair Ahsan, Ece Koldaş Ürer, Serkan İrfan Köse, Gökhan Doğruer

Turkish Journal of Veterinary & Animal Sciences

The objective of this study was to assess the changes in serum glucose, beta-hydroxybutyric acid (ß-HBA), and nonesterified fatty acid (NEFA) levels in Damascus dairy goats fed niacin (Nia) and methionine (Met) during late gestation and early postpartum period. A total of 75 dairy goats at 105th day of gestation were divided into 3 groups as control (no supplementation), Nia (20 g/kg Nia), and Met (2.5 g/kg Met) groups. The dietary treatments continued until parturition. Dairy goats fed dietary Nia had greater serum glucose levels on day 125 of gestation compared to the other dietary treatments (P < 0.05). On day 135 of pregnancy, serum glucose levels were higher in Met group than control group (P < 0.05). Serum ß-HBA levels decreased on days 135 and 145 in dairy goats fed Nia than those in control group. Dietary Nia and Met lowered serum ß-HBA levels on day 10 postpartum compared to control group (P < 0.05). Serum NEFA levels decreased (P < 0.05) on days 135 and 145 in dairy goats fed Nia supplemented ration than those in control group. Serum NEFA levels d 10 postpartum were different among the groups (P < 0.05). In conclusion, dietary Nia and Met supplementation improved serum glucose levels on day 125 of gestation while decreasing ß-HBA and NEFA levels during late gestation and early postpartum period in Damascus dairy goats under the conditions of present study.

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Evaluation Of Gait Character Of Akbaş And Kangal Shepherd Dogs By Using Pressuresensitive Walkway, Ozan Gündemi̇r, Hasan Alpak, Di̇lek Olğun Erdi̇kmen, Di̇dar Aydin Kaya Jan 2020

Evaluation Of Gait Character Of Akbaş And Kangal Shepherd Dogs By Using Pressuresensitive Walkway, Ozan Gündemi̇r, Hasan Alpak, Di̇lek Olğun Erdi̇kmen, Di̇dar Aydin Kaya

Turkish Journal of Veterinary & Animal Sciences

In this study, it was aimed to evaluate which walking analysis data may be obtained for Kangal and Akbaş shepherd dogs using a pressure-sensitive walkway (PSW) and which of these data may be used in the fields of veterinary anatomy, orthopedics, and neurology. Center of pressure (COP) analysis results of 46 dogs were examined. Distance type gait parameters of dogs were measured and their foot zone analysis values were recorded. It was observed that the pressure values applied by forelimb steps on the ground were higher compared to the pressure applied by hindlimb steps. The highest peak vertical force (PVF) …

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Assessment Of Changes In The Saliva Cortisol Level Of Horses During Different Waysin Recreational Exploitation, Boguslawa Dlugosz, Tomasz Próchniak, Monika Stefaniuk-Szmukier, Marta Basiaga, Jaroslaw Luszczynski, Magdalena Pieszka Jan 2020

Assessment Of Changes In The Saliva Cortisol Level Of Horses During Different Waysin Recreational Exploitation, Boguslawa Dlugosz, Tomasz Próchniak, Monika Stefaniuk-Szmukier, Marta Basiaga, Jaroslaw Luszczynski, Magdalena Pieszka

Turkish Journal of Veterinary & Animal Sciences

The aim of this study was to evaluate the saliva cortisol levelsof recreational horses dependent on the type of horse activity. A total of 68 horses were included in the experiment and divided into groups according to recreational activity, type of horse, age, term of saliva collection, and sex. Saliva samples were obtained from each horse at 3 measurement points: in the morning (6 a.m.), in the evening (6 p.m.), and immediately after work. The overall analysis shows that the term of sample collection, recreational activity, and age influence cortisol concentration. The diurnal concentration of saliva cortisol does not differ …

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Evaluation Of Larval Culture And Conventional Pcr Methods For The Detection Ofstrongylus Vulgaris In Equines Of Iran, Alireza Alborzi, Sara Larki, Abbas Zeinali Jan 2020

Evaluation Of Larval Culture And Conventional Pcr Methods For The Detection Ofstrongylus Vulgaris In Equines Of Iran, Alireza Alborzi, Sara Larki, Abbas Zeinali

Turkish Journal of Veterinary & Animal Sciences

Strongylus vulgaris (S. vulgaris) is known as the equin's most pathogenic nematode due to the extraintestinal migration in mesenteric arterial vessels. Since a few kinds of S. vulgaris can threat the animals' health and working efficiency, high precision and early detection of strongylid nematodes is essential. Traditionally, the larval coproculture method was used frequently for identification of strongylid species. The technique of larval culture is costly, time consuming, and does not have sufficient accuracy and reliability. Here, we critically evaluated the polymerase chain reaction (PCR) with larval culture methods for the detection of S. vulgaris eggs in fecal samples. To …

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Extended Spectrum Beta-Lactamase (Esßl), Ampc And Carbapenemase Activities Andcolistin Resistance Of Salmonella Spp. Isolated From Food Poisoning Cases In Turkey, Si̇bel Kizil Jan 2020

Extended Spectrum Beta-Lactamase (Esßl), Ampc And Carbapenemase Activities Andcolistin Resistance Of Salmonella Spp. Isolated From Food Poisoning Cases In Turkey, Si̇bel Kizil

Turkish Journal of Veterinary & Animal Sciences

This study aims at detecting antimicrobial resistance properties including extended spectrum beta-lactamase (ESBL), AmpC, carbapenemase activities (imipenem, meropenem and ertapenem), and colistin resistance of isolated and serotyped Salmonella spp. strains from various foods (mostly chicken and chicken products) that cause food poisoning. The ISO 6579-3 (Kaufmann-White scheme) method was used for serotyping of Salmonella spp. and for detection of antimicrobial resistance with Minimum Inhibitory Concentration (MIC) as reported by EURL-AR. Inoculums were separated into EUVSEC and EUVSEC2 panels using the Sensititre AIM Automated Inoculation Delivery System. The results were monitored in a semiautomatic vision reader and evaluated according to EUCAST. …

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Effects Of Activated Charcoal And Zeolite On Serum Lipopolysaccharides And Someinflammatory Biomarkers Levels In Experimentally Induced Subacute Ruminal Acidosis Inlambs, Ali Abbas Nikvand, Mohammad Nouri, Mohammad Razi Jalali, Mohammad Reza Teimory Azadbakht Jan 2020

Effects Of Activated Charcoal And Zeolite On Serum Lipopolysaccharides And Someinflammatory Biomarkers Levels In Experimentally Induced Subacute Ruminal Acidosis Inlambs, Ali Abbas Nikvand, Mohammad Nouri, Mohammad Razi Jalali, Mohammad Reza Teimory Azadbakht

Turkish Journal of Veterinary & Animal Sciences

Bacterial lipopolysaccharides (LPS) play a key role in the pathogenesis of subacute ruminal acidosis (SARA). Limited attempts have been made to inhibit LPS absorption during SARA. Therefore, this study aimed to evaluate the impacts of oral usage of activated charcoal and zeolite on serum LPS and acute phase proteins (APPs) levels in lambs with SARA. Fifteen lambs were randomly assigned to 3 groups, each containing 5 lambs: control, activated charcoal, and zeolite. In all groups, SARA was induced for 7 days through increasing the crushed corn ration to 52.8% and reducing the rumen pH to the range of 5.7-5.6. In …

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Biosecurity Levels Of Livestock Enterprises In Turkey And Factors Affecting These Levels, Mehmet Feri̇t Can, Nuri̇ Altuğ, Ferhan Kaygisiz Jan 2020

Biosecurity Levels Of Livestock Enterprises In Turkey And Factors Affecting These Levels, Mehmet Feri̇t Can, Nuri̇ Altuğ, Ferhan Kaygisiz

Turkish Journal of Veterinary & Animal Sciences

Biosecurity (BS) is a multidimensional preventive medicine approach that has health, technical, and financial aspects. The purpose of this study was to determine the differences of the BS scores belonging to the livestock enterprises depending on the geographical region and breeding types and to predict the socioeconomic factors having an impact over the BS level. The study was conducted with 517 breeders who live in 7 different regions of Turkey. The results have revealed that the enterprises performing "beef cattle fattening and dairy cattle breeding together" have higher BS scores than the enterprises in the other breeding category (P < 0.01). The differences between the technical and financial scores according to geographical regions were statistically significant (P < 0.01). The regions categorized as "wes" have the highest score and "south" have the lowest score. It was determined that as the "educational level of the breeder" and "enterprise scale" increased, the BS score significantly went up. The regression model was found significant as a whole (P < 0.01) and the independent variables explained the variation in the technical and financial BS scores to be 14.6% and 12.7%, respectively. Dissemination of education/training practices and increasing enterprise scales will positively affect the level of BS in the sector.

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Faculty Authors & Achievers Bibliography 2020, Luke Vilelle Jan 2020

Faculty Authors & Achievers Bibliography 2020, Luke Vilelle

WRL: Faculty Authors & Achievers Bibliographies

The office of the Vice President for Academic Affairs and the Wyndham Robertson Library congratulate all Hollins faculty who published or presented creative or scholarly works from Fall 2018 - Summer 2020. These pages include a list of those activities.

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Flooding And Industrial Swine Farming In North Carolina: Implications Of Natech Hazards On The Assessment Of Environmental Justice, Jacob Ramthun Jan 2020

Flooding And Industrial Swine Farming In North Carolina: Implications Of Natech Hazards On The Assessment Of Environmental Justice, Jacob Ramthun

Theses and Dissertations

“Natech” events, in which natural hazards trigger anthropogenic hazards, are becoming increasingly common. Methodologies for measuring the impact of natech events on environmental justice assessments are lacking, particularly in rural scenarios. This study used additive, multiplicative, and z-score threshold methods of combining the density of industrial swine farms in eastern North Carolina and the presence of flood risk to determine whether or not natech risk exhibits emergent socioeconomic indicators and whether areas of high natech constitute environmental injustice. The multiplicative and z-score threshold methods generated variables representing natech risk to compare to socioeconomic indicators, as well as statistically significant hotspots. …

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Expressions, Winter 2020, San Jose State University, College Of The Humanities And The Arts Jan 2020

Expressions, Winter 2020, San Jose State University, College Of The Humanities And The Arts

Expressions (College of Humanities and the Arts)

College of Humanities and the Arts Newsletter

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The Midsession Reversal Task With Pigeons: Effects Of A Brief Delay Between Choice And Reinforcement, Megan Ashley Halloran Jan 2020

The Midsession Reversal Task With Pigeons: Effects Of A Brief Delay Between Choice And Reinforcement, Megan Ashley Halloran

Theses and Dissertations--Psychology

During a midsession reversal task, the session begins with a simple simultaneous discrimination in which one stimulus (S1) is correct and the alternate stimulus (S2) is incorrect (S1+/S2-). At the halfway point, the discrimination reverses and S2 becomes the correct choice (S2+/S1-). When choosing optimally, a pigeon should choose S1 until the first trial in which it is not reinforced and then shift to S2 (win-stay/lose-shift). With this task pigeons have been shown to respond suboptimally by anticipating the reversal (anticipatory errors) and continuing to choose S1 after the reversal (perseverative errors). This suboptimal behavior may result from a pigeon’s …

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Elementary School Children’S Understanding Of Disproportionate Discipline, Sharla D. Biefeld Jan 2020

Elementary School Children’S Understanding Of Disproportionate Discipline, Sharla D. Biefeld

Theses and Dissertations--Psychology

In the U.S. Black students, particularly Black boys, receive more out of school punishments, are punished more frequently, and are punished for more subjective behaviors than their White peers (Skiba, Michael, Nardo, & Peterson, 2002). This phenomenon is referred to as disproportionate discipline and is an early precursor to the disproportionate number of Black men and boys incarcerated in the U.S. Disproportionate discipline begins as early as preschool, and continues throughout elementary, middle, and high school (Gregory & Fergus, 2017). Perceptions of discrimination greatly impact children’s school involvement, school belonging, and educational outcomes (Brown, 2017, for review). However, little is …

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Attentional Control In Infancy: The Role Of Sociodemographic Risk, Cortisol, And The Home Environment, Hannah B. White Jan 2020

Attentional Control In Infancy: The Role Of Sociodemographic Risk, Cortisol, And The Home Environment, Hannah B. White

Theses and Dissertations--Psychology

Infants’ ability to channel their cognitive resources by controlling their visual attention allows them to be active agents in their learning and development. Individual differences in attentional control have been linked to a wide variety of developmental outcomes including disparities between social classes in cognitive functioning. However, it is yet unknown when in development differences in attentional control related to sociodemographic factors emerge, or how factors of the home environment and the infant’s stress response relate to this effect. Accordingly, Experiment 1 examined whether certain sociodemographic factors, such as socioeconomic and minority status, predict 3.5-month-old infants’ (N = 102) …

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Ethanol Sustains Phosphorylated Tau Protein Immunofluorescence In The Cultured Neonatal Rat Hippocampus: Implications For Fetal Alcohol Spectrum Disorders, Caleb Seth Bailey Jan 2020

Ethanol Sustains Phosphorylated Tau Protein Immunofluorescence In The Cultured Neonatal Rat Hippocampus: Implications For Fetal Alcohol Spectrum Disorders, Caleb Seth Bailey

Theses and Dissertations--Psychology

Fetal Alcohol Spectrum Disorders (FASDs) are comprised of developmental, behavioral, and cognitive abnormalities caused by prenatal alcohol exposure, affecting an estimated 2%-5% of childrenand costing up to $4 billion annually in the United States alone. Although some behavioral therapies can help, the biochemical mechanisms that underpin FASDs need further elucidation for development of more efficacious therapeutics. The tau protein modulates cytoskeletal structure in neurons, and thereby plays an integral role in proper development and function of the central nervous system, but its function is altered by its phosphorylation state, such that increased phosphorylation reduces tau protein function. The tau protein …

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Escalation And Reinstatement Of Fentanyl Self-Administration In Male And Female Rats, Samantha G. Malone Jan 2020

Escalation And Reinstatement Of Fentanyl Self-Administration In Male And Female Rats, Samantha G. Malone

Theses and Dissertations--Psychology

Escalation of intake and craving are two DSM-5 hallmark symptoms of opioid use disorder (OUD). Objectives: This study determined if escalation measured by long access (LgA) self-administration and craving measured by reinstatement are related. Adult male and female Sprague-Dawley rats were trained to self-administer (SA) fentanyl across 7 daily 1-h sessions, followed by 21 SA sessions of either 1- or 6-h duration. Assignment to short access (ShA) and long access (LgA) groups was randomly determined for both males and females. Following 14 1-h extinction sessions, Experiment 1 assessed reinstatement induced by either fentanyl (10 or 30 μg/kg) or yohimbine (1 …

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Dog Whistle Politics: The Trump Administration's Influence On Hate Crimes, Susan V. Koski, Lp.D., Kathleen Bantley, Esq. Jan 2020

Dog Whistle Politics: The Trump Administration's Influence On Hate Crimes, Susan V. Koski, Lp.D., Kathleen Bantley, Esq.

Seton Hall Journal of Legislation and Public Policy

No abstract provided.

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Synthesis And Design Of Novel Polymer Grafted Nanoparticles Relevant To Drug Delivery Vehicles For Biomedical Application, Maan Abduldiyem Hassan Al-Ali Jan 2020

Synthesis And Design Of Novel Polymer Grafted Nanoparticles Relevant To Drug Delivery Vehicles For Biomedical Application, Maan Abduldiyem Hassan Al-Ali

Theses and Dissertations

The modification of inorganic nanoparticles with organic polymer chains has become a significant field of study for the engineering of advanced nanocomposite materials. This dissertation presents the design, synthesis, and characterization of novel polymer grafted silica nanoparticles as new strategies to combat bacterial resistance. Described herein is the synthesis of monomers that have been graft polymerized onto silica nanoparticles that can be used as a delivery drug vehicle for biomedical applications. The polymerization of these monomers was performed via reversible addition-fragmentation chain transfer (RAFT) polymerization. The molecular design of the RAFT agents that are attached to the surfaces of the …

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Selectivity For Allosteric Effectors Of Bacterial Adp-Glucose Pyrophosphorylase: Structural And Functional Studies, Mashael Alghamdi Jan 2020

Selectivity For Allosteric Effectors Of Bacterial Adp-Glucose Pyrophosphorylase: Structural And Functional Studies, Mashael Alghamdi

Dissertations

The biosynthesis of the intracellular polysaccharide in bacteria and plants, glycogen and starch, respectively, controlled by the key regulatory step that catalyzed by ADP-Glucose Pyrophosphorylase (ADP-Glc PPase). ADP-Glc PPase is an allosteric enzyme regulated by metabolites produced of the principle carbon assimilation pathway in each organism. Agrobacterium tumefaciens enzyme activated by fructose 6-phosphate (Fru6P) and pyruvate, whereas Escherichia coli enzyme activated by fructose 1,6-bisphosphate (FBP), and both enzymes inhibited by AMP. Here, we targeted the allosteric regulation of the A. tumefaciens enzyme, examined some residues that may impact the regulation mechanism (Ser72, His71, Arg75, Ser351, Ser334, Arg368, Asn350, and Asp291), …

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Women And Strategies Of Violence: Gender Roles, Foreign Support And Maintaining The Rebellion, Caglayan Baser Jan 2020

Women And Strategies Of Violence: Gender Roles, Foreign Support And Maintaining The Rebellion, Caglayan Baser

Dissertations

How do women affect conflict dynamics in different ways than men? I examine how expectations based on gender identities impact rebel group strategies, as well as attitudes of foreign publics and political elites toward rebel groups. First, women can substantially contribute to rebel groups' ability to resist governments and maintain their rebellion through unique gendered ways. These include enabling greater tactical diversity, increased appeal to international audiences, and spearheading coup-proofing strategies against intra-organizational factions. Women's contributions to rebel groups are most salient during times of crises and in settings where gender stereotypes are stronger. Second, rebel groups with women participants …

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Dietary Intake And Executive Function In Youth And Emerging Adulthood: Environmental Correlates And Developmental Considerations, Amy Michelle Egbert Jan 2020

Dietary Intake And Executive Function In Youth And Emerging Adulthood: Environmental Correlates And Developmental Considerations, Amy Michelle Egbert

Dissertations

Obesity is a major public health concern impacting one in five young people in the U.S., and research suggests that consumption of high calorie, low nutrient foods may play a role in weight gain. Executive function (EF) has emerged as a factor that may play a role in dietary intake across youth development. Although biopsychosocial models of obesity emphasize the importance of identifying individual and environmental influences that may be associated with poor dietary intake, empirical research in this area is lacking. Therefore, the current set of studies seeks to 1) systematically review the literature on the association between EF …

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