Digital Commons Network^™

C-Reactive Protein Subverts The Myeloid Lineage: Implications For Renal Injury, Rachel Jimenez

All ETDs from UAB

C-reactive protein (CRP) is an evolutionarily conserved pattern recognition molecule that was first characterized for its participation in the acute phase response to bacterial infection. In the last 90 years, knowledge of CRP biology in innate immunity has expanded significantly. CRP is known to bind and activate the classical pathway of complement, to opsonize bacteria and inflamed tissue, and to modulate myeloid cell functions. CRP is normally present in the blood at low levels with its biosynthesis and serum concentration rapidly rises upon systemic inflammation. For example, high levels of serum CRP are found following acute kidney injury (AKI) in …

Quest Towards The Development Of Human Cardiac Tissue Equivalents Made From Human Induced Pluripotent Stem Cell Derived Cardiac Cells, Wesley Labarge

All ETDs from UAB

The human heart is one of the more complex organs in the body to study and understand given the structural and functional characteristics it possesses. These characteristics work in synchrony to transfer oxygen-rich blood to vital organs throughout the body and oxygen-deficient blood back to the lungs for oxygenation. Furthermore, it can be reasoned that when these complexities are compounded with disease states which negatively affect the structure and function of the heart, determining the best treatments while also limiting adverse side effects becomes increasingly more challenging. While the goal of having patient-specific therapies has not completely been realized, the …

Understanding And Targeting Glucose Transporter 3 In Glioblastoma, Catherine Jeanne Libby

All ETDs from UAB

Glioblastoma (GBM) is the most common adult primary malignant brain tumor with a median survival of about 15 months, even after aggressive treatment. Treatment of GBM is difficult for multiple reasons including the location of the tumor, tumor invasiveness, and the high degree of both inter-and intra-tumoral heterogeneity. Contributing to intratumoral heterogeneity are highly tumorigenic, stem-like tumor cells, with the capacity to self-renew and propagate the tumor, termed brain tumor initiating cells (BTICs). BTICs are also commonly therapy resistant, highly invasive, and metabolically plastic with elevated expression of glucose transporter 3 (GLUT3) allowing them to preferentially survive in low nutrient …

Single Cell Proteins Affect Growth Performance And Body Composition Of Pacific White Shrimp Litopenaeus Vannamei, Yuan Yuan

All ETDs from UAB

The globally growing human population has increased the needs for protein based food. Single cell proteins (SCPs) as unconventional protein source, when coupled to aq-uaculture production, offer a means to ensure future protein needs can be met. To demon-strate a given type of SCP has potential as a protein source for use in aquaculture feed; a number of investigations are needed including demonstrating that the SCP is attractable and accepted by the animals, leads to equivalent survival, growth and nutritional compo-sition. This dissertation represents a series of investigations designed to evaluate the fea-sibility of using a bacterial based (MRD-Pro) and …

Copper Dependent Inhibitors Subvert Common Resistance Mechanisms In Staphylococcus Aureus And Inhibit Crucial Metabolic Pathways, Cameron Crawford

All ETDs from UAB

The effective antibiotic pool is shrinking with antibiotic resistance a constant problem that threatens to make our current therapies obsolete. To combat this, new drug screening methodologies are required since the traditional drug screens are offering limited results or only improvements upon current treatments. This work expands upon the idea that transition metal toxicity can be preferentially targeted towards bacteria. Specifically, the focus is on copper dependent inhibitors that quickly work to eliminate Staphylococcus aureus. S. aureus is a particularly threatening bacteria with high strain variability, a litany of survival and virulence factors, and multiple drug resistance mechanisms that are …

Smoke Inhalation, Lung Function, And Heart Rate In Wildland Firefighters, Jordan E. Nelson

All ETDs from UAB

Given the close proximity to the fire front and limited use of respiratory protection, wildland firefighters are exposed to elevated levels of biomass smoke during regular occupational shifts. Due to the complex composition of biomass smoke, the relationships relating biomass smoke exposure to health outcomes has yet to be elucidated. In addition to occupational exposures, increasing intensity of wildfire events may place communities within close proximity to wildfires at risk of biomass smoke exposure. This study aimed to assess exposures to biomass smoke particles and quantify respiratory and cardiovascular health responses during active fire events using novel monitoring techniques. Personal …

Resilience, Resistance And Revival In 20th-Century Yoruba Art, Charles Mason, Andie Near

Kruizenga Art Museum Exhibition Catalogs

Kruizenga Art Museum, Hope College Catalog for exhibition: “Resilience, Resistance and Revival in 20th-Century Yoruba Art”. Exhibition dates: January 17—May 16, 2020. Charles Mason, author; Andie Near, photographer, designer; Lisa Barney, editor; Cecilia O’Brien ‘21, typographer.

Kruizenga Art Museum Online Collection - Exhibition Gallery

Colonial Patronage: Evolutions In The Critique Of Sartre’S “Orphée Noir”, Gus Huiskamp

Independent Study Project (ISP) Collection

One of the most interesting and controversial episodes in the history of the Négritude literary and philosophical movement came when two white, French authors prefaced the texts of two of the movement’s most significant authors. Jean-Paul Sartre’s “Orphée noir” is one of these texts in question, and it served as the preface for Léopold Sédar Senghor’s Anthologie de le nouvelle poésie nègre et malgache de langue française. In one sense, one might characterize Sartre as a friend to the Négritude movement, exposing it to the francophone mainstream and thereby helping it gain traction in Western academia. Viewed a different way, …

Therapeutic Interventions That Increase Engagement For Students With Autism, Rachel B. Berndt

All Electronic Theses and Dissertations

Students with autism require unique programming to increase engagement in the classroom setting. This literature review is a collection of research-based studies involving animal assisted interventions, music therapy, art therapy, speech-language therapy, occupational therapy, and cognitive behavioral therapy. The results of these studies suggest that when provided the therapeutic interventions listed above, students with autism increase engagement in the classroom due to the expansion of language and social communication skills and the decrease of maladaptive behaviors. Given purposeful and collaborative therapeutic interventions, students learn how to problem solve, collaborate, and communicate with adults and peers. Sensory processing challenges are addressed …

Community Teaching Experience: A Description Of The Development And Design Of A Unique Teaching Experience For Occupational Therapy Doctoral Students, Laura E. Landon, Christine Berg, Sara S. Ulfers

Journal of Occupational Therapy Education

Entry-level occupational therapy doctorate (OTD) students receive education and training to interpret and disseminate evidenced-based literature. However, these students are often missing the clinical experience to identify clinically relevant questions that impact occupational outcomes. Conversely, occupational therapy practitioners have the clinical experience to determine clinically appropriate questions but often encounter time, budget, and setting constraints on researching and learning up-to-date evidence-based practice assessment and intervention techniques. The purpose of this paper is to describe the development and design of an exploratory educational project in which OTD students utilized clinically relevant questions identified by local occupational therapy practitioners to disseminate evidence-based …

Creating And Sharing Digital Instructional Activities: A Practical Tutorial, Stephanie L. Mattson, Thomas S. Higbee, Juliana Aguilar, Beverly Nichols, Vincent E. Campbell, Lyndsay D. Nix, Kassidy S. Reinert, Sara Peck, Kylee Lewis

Special Education and Rehabilitation Counseling Faculty Publications

BCBAs may encounter situations, such as the current COVID-19 pandemic, that preclude them from providing traditional in-person ABA services to clients. When conditions prevent BCBAs and behavior technicians from working directly with clients, digital instructional activities designed by BCBAs and delivered via a computer or tablet may be a viable substitute. Google applications, including Google Slides, Google Forms, and Google Classroom, can be particularly useful for creating and sharing digital instructional activities. In the current paper, we provide task analyses for utilizing basic Google Slides functions, developing independent instructional activities, developing caregiver-supported instructional activities, and sharing activities with clients and …

Animal Science E-Newsletter, January 2020, University Of Arkansas, Fayetteville. Department Of Animal Sciences

Animal Science e-Newsletter

No abstract provided.

The Book Of Ezekiel And The Speculative Design, Ian Gonsher

Scholarly Research

In this essay, the origins of speculative literature are situated within the prophetic tradition of Jewish mysticism, particularly in the Book of Ezekiel. The Book of Ezekiel is also a text about design. We investigate how these ancient sources align with contemporary design discourses, particularly Speculative Design, and propose new strategies for the readings of historical progress.

Sequoya Review, University Of Tennessee At Chattanooga

Sequoya Review

No abstract provided.

Deconstruction Of The Construction: Derridean Study Of Selected Shakespeare’S Comedies, Seyyedeh Zahra Nozen, Pegah Sheikhalipour

Khazar Journal of Humanities and Social Sciences

Since it was first introduced by Jacques Derrida in the late 1960s, deconstruction, as a method of reading, has been applied to literary texts by critics to reveal the hidden messages of texts and provide opportunities to rethink textual and cultural norms and conventions. While the western tradition has always prioritized tragedy over comedy due to its elegance and graveness, this research tends to focus on comedy as an entity in itself. Tragedy, especially in the Shakespearean sense of the word, has been considered by critics as a “construction” which is well-wrought and perfect in nature. Comedy, on the other …

Mechanisms Of Hamstring Strain Injury: Interactions Between Fatigue, Muscle Activation And Function, Shaun Huygaerts, Francesc Cos, Daniel D. Cohen, Julio Calleja-Gonzalez, Marc Guitart, Anthony J. Blazevich, Pedro E. Alcarez

Research outputs 2014 to 2021

Isolated injury to the long head of biceps femoris is the most common type of acute hamstring strain injury (HSI). However, the precise hamstring injury mechanism (i.e., sprint-type) is still not well understood, and research is inconclusive as to which phase in the running cycle HSI risk is the greatest. Since detailed information relating to hamstring muscle function during sprint running cannot be obtained in vivo in humans, the findings of studies investigating HSI mechanisms are based on modeling that requires assumptions to be made based on extrapolations from anatomical and biomechanical investigations. As it is extremely difficult to account …

Remodeling The Skeletal Muscle Extracellular Matrix In Older Age—Effects Of Acute Exercise Stimuli On Gene Expression, Matthias Gumpenberger, Barbara Wessner, Alexandra Graf, Marco V. Narici, Christian Fink, Sepp Braun, Christian Hoser, Anthony J. Blazevich, Robert Csapo

Research outputs 2014 to 2021

© 2020 by the authors. Licensee MDPI, Basel, Switzerland. With advancing age, the skeletal muscle extracellular matrix (ECM) undergoes fibrotic changes that may lead to increased muscle stiffness, injury susceptibility and strength loss. This study tested the potential of different exercises to counter these changes by stimulating the activity of genes associated with ECM remodeling. Twenty-six healthy men (66.9 ± 3.9 years) were stratified to two of four groups, performing unilateral (i) conventional resistance exercise, (ii) conventional resistance exercise followed by self-myofascial release (CEBR), (iii) eccentric-only exercise (ECC) or (iv) plyometric jumps (PLY). The non-trained leg served as control. Six …

Texas Landfills: The Need For Administrative Reform Of The Texas Commission On Environmental Quality’S Permitting Process, William Todd Keller Jr.

St. Mary's Law Journal

Abstract forthcoming

Ethical Considerations For Prosecutors: How Recent Advancements Have Changed The Face Of Prosecution, Joshua L. Sandoval

St. Mary's Journal on Legal Malpractice & Ethics

The prosecutor acts as a minister of justice with sweeping discretion to charge an individual with a crime, plea a case in a manner supported by the strength of the evidence, proceed to trial on a case, and even dismiss a case. He must balance the interest of the victim, the community, and the constitutional rights of the accused in every decision he makes.

This article will explore the role of the American prosecutor and discuss various ethical issues encountered on a daily basis. After a brief introduction, the author will succinctly discuss the history of the prosecutor and will …

Behavioral Response Of Root-Knot Nematode, Meloidogyne Incognita, To Tomato, Solanum Lycopersicon, Root Exudates, Hillary Kipchirchir Kirwa

All Master’s Theses

Root-Knot Nematodes (RKNs) are major economically important group of plant parasitic nematodes distributed worldwide. RKNs cause over $100 billion yield losses annually on major crops. The damage caused to crops is due to plant root invasion by motile second stage juveniles (J2s). The J2s induce redifferentiation of the plant root cells into specialized feeding cells essential for nematode development. The hyperplasia and hypertrophy of cells surrounding the feeding cells lead to formation of typical root galls affecting transport of photosynthates from source to sink, and uptake of water and nutrients. Upon hatching from the eggs in the soil, J2s must …

Growth Performance And Carcass Characteristics Of The African Catfish (Clarias Gariepinus) Reared On Diets Containing Black Soldier Fly (Hermetia Illucens) Larvae Meal, Anderson Maina Njoroge

All Master’s Theses

Fish feed protein ingredients are the most expensive and often unavailable in subSaharan Africa especially in commercial aquaculture systems. The major fish feed protein ingredient in fish farming in Kenya is fishmeal (FM) that is often times expensive and adulterated leading to low productivity of fish farming. This problem has necessitated a need for exploring alternative less expensive and easily available protein sources such as black soldier fly larvae (BSFL). This study aimed at evaluating the growth rate, feed utilization, survivability and carcass characteristics of the African catfish (Clarias gariepinus) reared on diets containing BSFL meal as a replacement for …

Varroa-Specific Hygienic Behaviour And Population Abundance Of Varroa Destructor In Colonies Of Apis Mellifera Scutellate In Karura Forest, Kenya, Sammy Kiprotich Cheruiyot

All Master’s Theses

The ectoparasitic mite Varroa destructor is one of the parasiteglobally reported affecting honeybee healthand causing high colony losses.Of notable importance is the associationof the mite with viruses and their transmission to honeybees which causesgreatharm to bees. Kenyan beekeepers have reportedthat bee populationshave been ondecline in recent years and therefore the need for research to establish whether Varroa destructoris negativelyaffectinghoneybee survival and development.The objectives of thisstudy were to evaluate Varroa-specific hygienic behaviourof Apis mellifera scutellata,assess population abundanceof V. destructorand determine the effects of V. destructoron local honeybeeA.m.scutellata.The study was conducted at International Centre of Insect Physiology and Ecology (icipe)research apiaries located …

Deadly Drones? Why Faa Regulations Miss The Mark On Drone Safety, Steve Calandrillo, Jason Oh, Ari Webb

Articles

A rapidly growing commercial drone industry has prompted the introduction of numerous regulations governing American airspace. Congress has tasked the Federal Aviation Administration (FAA) with “developing plans for the use of the navigable airspace to ensure the safety of aircraft and the efficient use” of American skies. While well-intended, the FAA has departed from Congressional will by imposing an excessive regulatory regime that threatens to stifle drone technology and innovation. In fact, many FAA regulations fail to address the very problem they seek to fix, namely the safety of our airspace. The unfortunate result is that myriad scientific and pragmatic …

An Examination Of Social Connectedness On Ptsd And Freezing In A Student Military Population, Jessica Marie Ledwith

UNF Graduate Theses and Dissertations

This study investigates the impact of social connectedness (SC) and post-traumatic stress disorder (PTSD) in a military college population, and their relation to physiological measures such as body sway, heart rate (HR), and heat rate variability (HRV). According to previous research, people with PTSD are more likely to exhibit a freezing response to affective images. In the present study, we explore the potential freezing response for military personnel at the levels of PTSD symptom groups and social connectedness. We also investigate the possible buffering effect social connectedness has on the outcome of PTSD and freezing. There was a total of …

The Trial Of Jesus, Jonathan K. Van Patten

South Dakota Law Review

No abstract provided.

Using Accelerometer And Gyroscope Data In Common Mobile Devices To Assess Credibility, Joseph S. Valacich, Jeffrey L. Jenkins, Michael D. Byrd, David Kim, Manasvi Kumar, Parker A. Williams

Faculty Publications

An observational study examined the efficacy of using accelerometer and gyroscope (i.e., orientation) data from standard mobile devices to assess response credibility. Study participants played twenty rounds of a card game where they self-reported whether they won or lost each round. Participants received a base payment but could gain increased “bonus” payments by cheating. After the card game, participants were asked a “Yes-No” question whether they cheated while their orientation data was captured. We predicted that people concealing information about an adverse behavior (i.e., cheating), would result in differences in both absolute magnitude changes in acceleration and in rotation, as …

A Phylogenetic Analysis Of Mycoplasma Strains Circulating In Sheep Pneumonia In Thekars Region Of Turkey, Olcay Öztürkler, Sali̇h Otlu

Turkish Journal of Veterinary & Animal Sciences

This study aimed to investigate Mycoplasma species by cultural and molecular methods in 250 pneumonics and 30 healthy appearance sheep lungs brought from slaughterhouse and butcheries in the Kars region of Turkey. The phylogenetic positioning of the bacterial strains to be obtained in the present study was another remarkable outcome of the study. Mycoplasma isolation was achieved solely in 26 (10.4%) of 250 sheep lungs with pneumonia. Mycoplasma ovipneumoniae was found predominant species in 12 (46.15%) of samples and that was followed by Mycoplasma arginini in 4 (15.38%) of strains. Moreover, two samples were found to be co-infected with the …

Awareness And Adoption Level Of Subclinical Mastitis Diagnosis Among Dairy Farmers Ofpunjab, India, Vidya Nimbalkar, Harish Kumar Verma, Jaswinder Singh, Suresh Kumar Kansal

Turkish Journal of Veterinary & Animal Sciences

Subclinical mastitis (SCM) is a major and silent problem of public health concern. It causes higher economic losses with no initial visible changes in the appearance of milk or udder. Subclinically affected animals always remain a continuous source of infection. Most of the clinical mastitis (CM) cases start as subclinical; hence controlling SCM is the best way to reduce the incidence of diseases. A crosssectional study was carried out during 2018?19 in six districts from different agroclimatic zones of Punjab, India to describe awareness about various technologies and its adoption to diagnose SCM. The multistage random technique was used to …

Assessment Of Genetic Gain And Its Simulation For Performance Traits In Sahiwal Cattle, Poonam Ratwan, Atish Kumar Chakravarty, Manoj Kumar

Turkish Journal of Veterinary & Animal Sciences

The study was conducted to estimate the expected genetic gain (ΔG) for first lactation performance traits in Sahiwal cattle as a result of direct selection of animals maintained at the ICAR-National Dairy Research Institute in India. Data pertaining to 305-day milk yield (305DMY), wet average (WA), and calving to first insemination interval (CFI) of the animals considering 13 counts of progenies/ sire were initially analyzed. The ΔG through direct selection was 43.68 kg/year, 0.13 kg/year, and 1.68 days/year for 305DMY, WA, and CFI, which was 1.97%, 1.65%, and 2.02% of herd average, respectively. In addition, ΔG was estimated by simulating …

Evaluation Of Animal Models For Genetic Analysis Of Growth Performance In Landlly Pigs, Snehasmita Panda, Gyanendra Kumar Gaur, Nihar Ranjan Sahoo, Sheikh Firdous Ahmad, Pruthviraj Devamma Ramachandrappa, Panch Kishor Bharti

Turkish Journal of Veterinary & Animal Sciences

Selection of the most appropriate animal model for the estimation of genetic parameters for body weight was carried out using restricted maximum likelihood (REML) procedure at birth and thereafter at 3, 6, and 8 weeks of age in Landlly pigs. Six different models were fitted for each trait; by inclusion or exclusion of maternal additive genetic effect, maternal permanent environmental effect, and covariance between direct and maternal additive genetic effects. Records on 1968 piglets, born in 4 parities of 131 gilts/sows, sired by 68 boars during a period of 5 years from 2014 to 2018 were used. In order to …