Digital Commons Network^™

A Role For Triglyceride Lipase Brummer In The Regulation Of Sex Differences In Drosophila Fat Storage And Breakdown, Lianna W. Wat, Chien Chao, Rachael Bartlett, Justin L. Buchanan, Jason W. Millington, Hui Ju Chih, Zahid S. Chowdhury, Puja Biswas, Vivian Huang, Leah J. Shin, Lin Chuan Wang, Marie-Pierre L. Gauthier, Maria C. Barone, Kristi L. Montooth, Michael A. Welte, Elizabeth J. Rideout

School of Biological Sciences: Faculty Publications

Triglycerides are the major form of stored fat in all animals. One important determinant of whole-body fat storage is whether an animal is male or female. Here, we use Drosophila, an established model for studies on triglyceride metabolism, to gain insight into the genes and physiological mechanisms that contribute to sex differences in fat storage. Our analysis of triglyceride storage and breakdown in both sexes identified a role for triglyceride lipase brummer (bmm) in the regulation of sex differences in triglyceride homeostasis. Normally, male flies have higher levels of bmm mRNA both under normal culture conditions and …

Trade-Offs Between Morphology And Thermal Niches Mediate Adaptation In Response To Competing Selective Pressures, Stella F. Uiterwaal, Ian T. Lagerstrom, Thomas M. Luhring, Miranda E. Salsbery, John P. Delong

School of Biological Sciences: Faculty Publications

The effects of climate change—such as increased temperature variability and novel predators—rarely happen in isolation, but it is unclear how organisms cope with mul- tiple stressors simultaneously. To explore this, we grew replicate Paramecium caudatum populations in either constant or variable temperatures and exposed half to predation. We then fit thermal performance curves (TPCs) of intrinsic growth rate (r_max) for each replicate population (N = 12) across seven temperatures (10°C–38°C). TPCs of P. caudatum exposed to both temperature variability and predation re- sponded only to one or the other (but not both), resulting in unpredictable outcomes. …

Extreme Offspring Ornamentation In American Coots Is Favored By Selection Within Families, Not Benefits To Conspecific Brood Parasites, Bruce E. Lyon, Daizaburo Shizuka

School of Biological Sciences: Faculty Publications

Offspring ornamentation typically occurs in taxa with parental care, suggesting that selection arising from social interactions between parents and offspring may underlie signal evolution. American coot babies are among the most ornamented offspring found in nature, sporting vividly orange-red natal plumage, a bright red beak, and other red parts around the face and pate. Previous plumage manipulation experiments showed that ornamented plumage is favored by strong parental choice for chicks with more extreme ornamentation but left unresolved the question as to why parents show the preference. Here we explore natural patterns of variation in coot chick plumage color, both within …

An Ortholog Of The Vasa Intronic Gene Is Required For Small Rna-Mediated Translation Repression In Chlamydomonas Reinhardtii, Xinrong Ma, Fadia Ibrahim, Eun-Jeong Kim, Scott Shaver, James Becker, Fareha Razvi, Ronald L. Cerny, Heriberto D. Cerutti

School of Biological Sciences: Faculty Publications

Small RNAs (sRNAs) associate with Argonaute (AGO) proteins in effector complexes, termed RNA-induced silencing complexes (RISCs), which regulate complementary transcripts by translation inhibition and/or RNA degradation. In the unicellular alga Chlamydomonas, several metazoans, and land plants, emerging evidence indicates that polyribosome-associated transcripts can be translationally repressed by RISCs without substantial messenger RNA (mRNA) destabilization. However, the mechanism of translation inhibition in a polyribosomal context is not understood. Here we show that Chlamydomonas VIG1, an ortholog of the Drosophila melanogaster Vasa intronic gene (VIG), is required for this process. VIG1 localizes predominantly in the cytosol and comigrates with monoribosomes and …

Coproid Predicts The Source Of Coprolites And Paleofeces Using Microbiome Composition And Host Dna Content, Maxime Borry, Bryan Cordova, Angela Perri, Marsha Wibowo, Tanvi Prasad Honap, Jada Ko, Kate Britton, Linus Girdland-Flink, Robert C. Power, Ingelise Stuijts, Domingo C. Salazar-García, Courtney Hofman, Richard Hagan, Thérèse Samdapawindé Kagoné, Nicolas Meda, Helene Carabin, David Jacobson, Karl Reinhard, Cecil Lewis, Aleksandar Kostic, Choongwon Jeong, Alexander Herbig, Alexander Hübner, Christina Warinner

Karl Reinhard Publications

Shotgun metagenomics applied to archaeological feces (paleofeces) can bring new insights into the composition and functions of human and animal gut microbiota from the past. However, paleofeces often undergo physical distortions in archaeological sediments, making their source species difficult to identify on the basis of fecal morphology or microscopic features alone. Here we present a reproducible and scalable pipeline using both host and microbial DNA to infer the host source of fecal material. We apply this pipeline to newly sequenced archaeological specimens and show that we are able to distinguish morphologically similar human and canine paleofeces, as well as non-fecal …

Diet Analysis Reveals Pre-Historic Meals Among The Loma San Gabriel At La Cueva De Los Muertos Chiquitos, Rio Zape, Mexico (600–800 Ce), Elisa Pucu, Julia Russ, Karl Reinhard

Karl Reinhard Publications

Coprolites have been a source of study for archeologists due to several reasons: they not only provide information on the life and nutritional habits of ancient individuals but also on their health. In this paper, we processed 10 coprolites collected at La Cueva de Los Muertos Chiquitos (600–800 CE), Rio Zape, Mexico, with acetolysis solution for pollen analysis. The number of pollen grains/gram of each coprolite sample was quantified along with the macroscopic remains of these samples. The main food item ingested by the population was maize, followed by Agave. Squash blossoms were also part of their food source …

Pinworm Research In The Southwest Usa: Five Decades Of Methodological And Theoretical Development And The Epidemiological Approach, Morgana Camacho, Karl Reinhard

Karl Reinhard Publications

Pinworms infected Ancestral Pueblo populations since early periods of occupation on the Colorado Plateau. The high prevalence of pinworm found in these populations was correlated with the habitation style developments through time. However, in previous studies, Turkey Pen Cave, an early occupation site, and Salmon Ruins, a late occupation site, exhibited prevalences that were anomalously low, suggesting that these sites were outliers. Alternatively, it is possible that the previous quantification method was not successful in detecting the real prevalence and eggs per gram, which led to inexact interpretations. The aims of this study were to verify if previous pinworm prevalences …

Effects Of Sentence-Combining Instruction For Spanish-Speaking Language-Minority Students: Evidence From Two Single-Case Experiments, J. Marc Goodrich, Michael Hebert, Mackenzie E. Savaiano, Tim Andress

Department of Special Education and Communication Disorders: Faculty Publications

Research indicates that sentence-combining instruction is effective for improving writing outcomes; however, no studies to date have examined the effects of sentence- combining instruction on the writing skills of Spanish- speaking language-minority (LM) students. Therefore, the purpose of this study was to examine the effects of explicit sentence-combining instruction that focused on correct adjective use when used with Spanish-speaking LM students with poor sentence construction skills. Across two studies, seven Spanish-speaking LM children in third to fifth grade participated in sentence-combining inter- ventions designed to teach adjective placement. Results in- dicated that there was a functional relation between the in- …

Eb4cast Approach Improves Science Communication With Stakeholders In A College-Based Health Program, Melissa D. Olfert, Makenzie L. Barr, Rebecca L. Hagedorn, Rahel A. Wattick, Wenjun Zhou, Tanya M. Horacek, Anne E. Mathews, Kendra K. Kattlemann, Tandalayo Kidd, Adrienne A. White, Onikia N. Brown, Jesse Stabile Morrell, Lisa Franzen-Castle, Karla P. Shelnutt, Carol Byrd-Bredbenner, Terezie Tolar-Peterson, Geoffrey W. Greene, Sarah E. Colby

Department of Nutrition and Health Sciences: Faculty Publications

Communicating scientific results with community partners is often lacking in intervention programs, thus eB4CAST was developed to facilitate impact sharing. This article investigated using the eB4CAST dissemination tool to communicate impact from a campus-based obesity prevention program. Data from Get Fruved RCT university sites collected at baseline were used to generate eB4CAST reports. Experts (n = 13) and RCT sites (n = 15) were asked to provide feedback on eB4CAST reports based on appeal, understanding, and clarity. On all Likert items, participants rated above 7 on each (out of 10). Positive responses from open-ended questions included eB4CAST reports being clear, …

Acoustic Space Occupancy: Combining Ecoacoustics And Lidar To Model Biodiversity Variation And Detection Bias Across Heterogeneous Landscapes, Danielle I. Rappaport, J. Andrew Royle, Douglas C. Morton

United States Geological Survey: Staff Publications

There is global interest in quantifying changing biodiversity in human-modified landscapes. Ecoacoustics may offer a promising pathway for supporting multi-taxa monitoring, but its scalability has been hampered by the sonic complexity of biodiverse ecosystems and the imperfect detectability of animal-generated sounds. The acoustic signature of a habitat, or soundscape, contains information about multiple taxa and may circumvent species identification, but robust statistical technology for characterizing community-level attributes is lacking. Here, we present the Acoustic Space Occupancy Model, a flexible hierarchical framework designed to account for detection artifacts from acoustic surveys in order to model biologically relevant variation in acoustic space …

Human-Associated Species Dominate Passerine Communities Across The United States, Helen R. Sofaer, Curtis H. Flather, Catherine S. Jarnevich, Kristin P. Davis, Liba Pejchar

United States Geological Survey: Staff Publications

Aim: Human development and agriculture can have transformative and homogenizing effects on natural systems, shifting the composition of ecological communities towards non-native and native species that tolerate or thrive under human-dominated conditions. These impacts cannot be fully captured by summarizing species presence, as they include dramatic changes to patterns of species abundance. However, how human land use patterns and species invasions intersect to shape patterns of abundance and dominance within ecological communities is poorly understood even in well-known taxa.

Location: Conterminous United States.

Time period: 2010–2012.

Major taxa studied: Passeriformes.

Methods: We analyse continental-scale monitoring data to study the proportional …

Ecosystem Processes, Land Cover, Climate, And Human Settlement Shape Dynamic Distributions For Golden Eagle Across The Western Us, J.D. Tack, Barry R. Noon, Zachary Bowen, Brad C. Fedy

United States Geological Survey: Staff Publications

Species–environment relationships for highly mobile species outside of the breeding season are often highly dynamic in response to the collective effects of everchanging climatic conditions, food resources, and anthropogenic disturbance. Capturing dynamic space-use patterns in a model-based framework is critical as model inference often drives place-based conservation planning. We applied dynamic occupancy models to broad-scale golden eagle Aquila chrysaetos survey data collected annually from 2006 to 2012 during the late summer post-fledging period in the western US. We defined survey sites as 10 km transect segments with a 1 km buffer on either transect side (n = 3540). Derived estimates …

Human-Associated Species Dominate Passerine Communities Across The United States, Helen R. Sofaer, Curtis H. Flather, Catherine S. Jarnevich, Kristin P. Davis

United States Geological Survey: Staff Publications

Aim: Human development and agriculture can have transformative and homogenizing effects on natural systems, shifting the composition of ecological communities towards non-native and native species that tolerate or thrive under human-dominated conditions. These impacts cannot be fully captured by summarizing species presence, as they include dramatic changes to patterns of species abundance. However, how human land use patterns and species invasions intersect to shape patterns of abundance and dominance within ecological communities is poorly understood even in well-known taxa.

Location: Conterminous United States.

Time period: 2010–2012.

Major taxa studied: Passeriformes.

Methods: We analyse continental-scale monitoring data to study the proportional …

Acoustic Space Occupancy: Combining Ecoacoustics And Lidar To Model Biodiversity Variation And Detection Bias Across Heterogeneous Landscapes, Danielle I. Rappaport, J. Andrew Royle, Douglas C. Morton

United States Geological Survey: Staff Publications

There is global interest in quantifying changing biodiversity in human-modified landscapes. Ecoacoustics may offer a promising pathway for supporting multi-taxa monitoring, but its scalability has been hampered by the sonic complexity of biodiverse ecosystems and the imperfect detectability of animal-generated sounds. The acoustic signature of a habitat, or soundscape, contains information about multiple taxa and may circumvent species identification, but robust statistical technology for characterizing community-level attributes is lacking. Here, we present the Acoustic Space Occupancy Model, a flexible hierarchical framework designed to account for detection artifacts from acoustic surveys in order to model biologically relevant variation in acoustic space …

Characterization Of Pallid Sturgeon (Scaphirhynchus Albus) Spawning Habitat In The Lower Missouri River, Caroline M. Elliott, Aaron J. Delonay, Kimberly Chojnacki, Robert B. Jacobson

United States Geological Survey: Staff Publications

Acipenseriformes (sturgeons and paddlefish) globally have declined throughout their range due to river fragmentation, habitat loss, overfishing, and degradation of water quality. In North America, pallid sturgeon (Scaphirhynchus albus) populations have experienced poor to no recruitment, or substantial levels of hybridization with the closely related shovelnose sturgeon (S. platorynchus). The Lower Missouri River is the only portion of the species’ range where successful reproduction and recruitment of genetically pure pallid sturgeon have been documented. This paper documents spawning habitat and behavior on the Lower Missouri River, which comprises over 1,300 km of unfragmented river habitat. The …

Simultaneous Cognate Epitope Recognition By Bovine Cd4 And Cd8 T Cells Is Essential For Primary Expansion Of Antigen-Specific Cytotoxic T-Cells Following Ex Vivo Stimulation With A Candidate Mycobacterium Avium Subsp. Paratuberculosis Peptide Vaccine, Gaber S. Abdellrazeq, Lindsay M. Fry, Mahmoud M. Elnaggar, J. P. Bannantine, David A. Schneider, William M. Chamberlin, Asmaa H.A. Mahmoud, Kun-Taek Park, Victoria Hulubei, William C. Davis

United States Department of Agriculture-Agricultural Research Service / University of Nebraska-Lincoln: Faculty Publications

Studies in cattle show CD8 cytotoxic T cells (CTL), with the ability to kill intracellular bacteria, develop following stimulation of monocyte-depleted peripheral blood mononuclear cells (mdPBMC) with antigen-presenting cells (APC, i.e. conventional dendritic cells [cDC] and monocyte-derived DC [MoDC]) pulsed with MMP, a membrane protein from Mycobacterium avium subsp. paratuberculosis (Map) encoded byMAP2121c. CTL activity was diminished if CD4 T cells were depleted from mdPBMC before antigen (Ag) presentation by APC, suggesting simultaneous cognate recognition of MMP epitopes presented by MHC I and MHC II molecules to CD4 and CD8 T cells is essential for development of CTL activity. To …

International Law And Theories Of Global Justice: Remarks, Steven R. Ratner, James Stewart, Jiewuh Song, Carmen Pavel

Articles

International law (IL) and political philosophy represent two rich disciplines for exploring issues of global justice. At their core, each seeks to build a better world based on some universally agreed norms, rules, and practices, backed by effective institutions. International lawyers, even the most positivist of them, have some underlying assumptions about a just world order that predisposes their interpretive methods; legal scholars have incorporated concepts of justice in their work even as their overall pragmatic orientation has limited the nature of their inquiries. Many philospophers, for their part, have engaged with IL to some extent—at a minimum recognizing that …

Proof At The Salem Witch Trials, Leonard M. Niehoff

Articles

As of the writing of this article, President Donald Trump's tweets have included roughly 400 references to "witch hunts." In a sense, this is unsurprising. The Salem witch trials have a special place in our national identity and vocabulary. Most Americans understand the reference, even if they know few of the historical details. And the phrase "witch hunt" serves as a useful shorthand for any frenzied chase after something that does not exist. The Salem trials also inspire a peculiar fascination: Perhaps no other site of deadly mass hysteria has become a major tourist destination.

Still, most practicing litigators probably …

The Impact Of Lifestyle Medicine On Nonalcoholic Fatty Liver Disease, Kelli L. Noble

DNP Research Projects

Nonalcoholic fatty liver disease (NAFLD) is the most common liver disease worldwide. The main risk factor for the development of NAFLD is metabolic syndrome. Women are at greatest risk, typically in their 5th to 6th decade of life. The more aggressive form of NAFLD is nonalcoholic steatohepatitis (NASH) which is characterized by inflammation associated with NAFLD. NASH has the greatest tendency to progress into cirrhosis. However, lifestyle intervention has been shown to effectively treat, and even reverse NAFLD. The purpose of this quantitative, quasi-experimental study was to lend additional research and demonstrate improvement in NAFLD through lifestyle intervention with 1) …

The Observational Investigation Of Vitamin D And The Effect On Hypertension (Oiveh) Study, Warren Burke

DNP Research Projects

Background

It is uncertain if vitamin D supplementation improves cardiovascular health, more specifically, the systolic and diastolic blood pressures, and the data from previous trials investigating supplementation and the effects on the blood pressure are limited.

Methods

The following scholarly project was a retrospective observational study, examining randomly selected participants with chronic kidney disease and hypertension from a local nephrology practice. The Student’s t-test, Pearson’s r correlation, and ANOVA statistical tests were utilized to determine if vitamin D supplementation improved the systolic and diastolic blood pressures.

Results

A total of 260 participants were examined. The mean systolic blood pressure …

Admissions Viewbook, 2020-2021, Illinois State University, Office Of Admissions

Admissions Viewbook

Recruitment booklet created by Illinois State University's Office of Admissions

High Fat Diet Significantly Changed The Global Gene Expression Profile Involved In Hepatic Drug Metabolism And Pharmacokinetic System In Mice., Yuqi He, Tao Yang, Yimei Du, Lin Qin, Feifei Ma, Zunping Wu, Hua Ling, Li Yang, Zhengtao Wang, Qingdi Zhou, Guangbo Ge, Yanliu Lu

PCOM Scholarly Works

Background: High fat diet impact transcription of hepatic genes responsible for drug metabolism and pharmacokinetics. Until now, researches just focused on a couple specific genes without a global profile showing. Age-dependent manner was also not noted well. This study aims to investigate the high fat diet effect on transcriptome of drug metabolism and pharmacokinetic system in mouse livers and show the age-dependent evidence.

Methods: C57BL/6 male mice were used in this experiment. High fat diet was used to treat mice for 16 and 38 weeks. Serum total cholesterol, low density lipoprotein cholesterol, aspartate transaminase, and alanine transaminaselevels were measured. Meanwhile, …

Myo/Nog Cells Are Nonprofessional Phagocytes, Jacquelyn Gerhart, Lindsay Gugerty, Paul Lecker, Fathma Abdalla, Mark Martin, Olivia Gerhart, Colby Gerhart, Karanveer Johal, Jake Bernstein, John Spikes, Keith Mathers, Arturo Bravo Nuevo, Mindy George-Weinstein

PCOM Scholarly Works

Myo/Nog cells were discovered in the chick embryo epiblast. Their expression of MyoD reflects a commitment to the skeletal muscle lineage and capacity to differentiate into myofibroblasts. Release of Noggin by Myo/Nog cells is essential for normal morphogenesis. Myo/Nog cells rapidly respond to wounding in the skin and eyes. In this report, we present evidence suggesting that Myo/Nog cells phagocytose tattoo ink in tissue sections of human skin and engulf cell corpses in cultures of anterior human lens tissue and magnetic beads injected into the anterior chamber of mice in vivo. Myo/Nog cells are distinct from macrophages in the skin …

Brain-Specific Angiogenesis Inhibitor 1 Is Expressed In The Myo/Nog Cell Lineage., Jacquelyn Gerhart, Jessica Bowers, Lindsay Gugerty, Colby Gerhart, Mark Martin, Fathma Abdalla, Arturo Bravo Nuevo, Jonathan Tabb Sullivan, Rebecca Rimkunas, Amie Albertus, Lou Casta, Lori Getts, Robert Getts, Mindy George-Weinstein

PCOM Scholarly Works

The Myo/Nog cell lineage was discovered in the chick embryo and is also present in adult mammalian tissues. The cells are named for their expression of mRNA for the skeletal muscle specific transcription factor MyoD and bone morphogenetic protein inhibitor Noggin. A third marker for Myo/Nog cells is the cell surface molecule recognized by the G8 monoclonal antibody (mAb). G8 has been used to detect, track, isolate and kill Myo/Nog cells. In this study, we screened a membrane proteome array for the target of the G8 mAb. The array consisted of >5,000 molecules, each synthesized in their native confirmation with …

When William T. Wiley And Bruce Nauman Wrote To H.C. Westermann, David Mccarthy

Art Inquiries

No abstract provided.

The Avant-Garde Networks Of Amauta: Argentina, Mexico, And Peru In The 1920s, Michele Greet

Art Inquiries

No abstract provided.

Art Making To Inform Dialogue Across Spiritual Otherness In The Therapeutic Space, Caitlin Brosious, Emma Burgin, Andrea Dyer, Maggie Knobbe

LMU Theses and Dissertations

This research was a preliminary pilot study meant to encourage further exploration on the intersection of art therapy, art making, spirituality, and dialogue. This study topic is an important area of investigation due to the long-standing challenges of interfaith dialogue, both historically and currently. An abundance of reviewed literature linking interfaith dialogue and dialogue through art making guided the research hypothesis, which states that the act of viewing and being viewed by the spiritual other through art making could deepen one’s own spiritual practice, increase empathy, foster dialogue, and inform clinical work as psychotherapists. To explore this, the researchers held …

Accessscience, Rob Tench

Libraries Faculty & Staff Publications

The article reviews the Web site AccessScience from publisher McGraw-Hill located at accessscience.com.

Early Surgery For Traumatic Spinal Cord Injury: Where Are We Now?, Jefferson R. Wilson, Christopher D. Witiw, Jetan Badhiwala, Brian K. Kwon, Michael G. Fehlings, James Harrop

Department of Neurosurgery Faculty Papers

Study Design: Narrative review.

Objective: There is a strong biological rationale to perform early decompression after traumatic spinal cord injury (SCI). With an enlarging clinical evidence base, most spine surgeons internationally now favor early decompression for the majority of SCI patients; however, a number of pertinent questions remain surrounding this therapy.

Methods: A narrative review evaluating the status of early surgery for SCI. In particular, we addressed the following questions: (1) Which patients stand to benefit most from early surgery? 2) What is the most appropriate time threshold defining early surgery?

Results: Although heterogeneity exists, the evidence generally seems to …

Conserving Spawning Stocks Through Harvest Slot Limits And No-Take Protected Areas, Gaya Gnanalingam, Holly Gaff, Mark J. Butler Iv

Biological Sciences Faculty Publications

The key to the conservation of harvested species is the maintenance of reproductive success. Yet for many marine species large, old individuals are targeted despite their disproportionate contribution to reproduction. We hypothesized that a combination of no-take marine protected areas (MPAs) and harvest slot limits (maximum and minimum size limits) would result in the conservation of large spawning individuals under heavy harvest. We tested this approach under different harvest intensities with a 2-sex, stage-structured metapopulation model for the Caribbean spiny lobster (Panulirus argus). P. argus is intensively harvested in the Caribbean, and in many localities large, mature individuals no longer …