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2020

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Algorithms For Inferring Multiple Microbial Networks, Sahar Tavakoli Jan 2020

Algorithms For Inferring Multiple Microbial Networks, Sahar Tavakoli

Electronic Theses and Dissertations, 2020-2023

The interactions among the constituent members of a microbial community play a major role in determining the overall behavior of the community and the abundance levels of its members. These interactions can be modeled using a network whose nodes represent microbial taxa and edges represent pairwise interactions. A microbial network is a weighted graph that is constructed from a sample-taxa count matrix and can be used to model co-occurrences and/or interactions of the constituent members of a microbial community. The nodes in this graph represent microbial taxa and the edges represent pairwise associations amongst these taxa. A microbial network is …

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Stage Fright: An Examination Of Horror-Based Theatre Through Theory And Practice, Ramon Paradoa Jan 2020

Stage Fright: An Examination Of Horror-Based Theatre Through Theory And Practice, Ramon Paradoa

Electronic Theses and Dissertations, 2020-2023

The horror genre wears masks of various shapes, sizes, and textures in the creative outlets in which it exists. While often criticized and chastised by the craftiest of pop culture critics, the general agreement is that the genre successfully fulfills its purpose in satisfying a craving for screams while providing a sub-cultured home for a specific demographic of misfits. Although the reasoning behind the genre's ever-growing popularity and continued financial success can easily be accredited to surface-level identifiers such as these, for the purposes of horror-based theatre, I believe they can more accurately be attributed to reasons far more psychoanalytical. …

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Who Am I, And Why Does It Matter? Reflections Of Identity And The Need For Culturally Sustaining Theatre, Bianca Alamo Jan 2020

Who Am I, And Why Does It Matter? Reflections Of Identity And The Need For Culturally Sustaining Theatre, Bianca Alamo

Electronic Theses and Dissertations, 2020-2023

The question of "who am I" created an involuntary domino effect which led me to my most valued work I have done as a graduate student, serving predominantly Latino/a students in educational theatre settings. This thesis explores three productions I worked on and the questions that have evolved in my understanding of identity and cultural sustainability as a Latina theatre artist and educator working in educational theatre. As an Orlando Repertory teaching artist, I began a residency with HOPE CommUnity Center along with some colleagues. We worked with high school students from their youth group to devise a show titled …

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Just A Number: A Cabaret Exploring The Roles My Age Prevents Me From Playing, Monica Andrews Jan 2020

Just A Number: A Cabaret Exploring The Roles My Age Prevents Me From Playing, Monica Andrews

Electronic Theses and Dissertations, 2020-2023

Learning your type in the entertainment industry is not an easy lesson for many young performers. This is especially true if you are already being cast as the 'older woman' or 'witty sidekick' at 13 years old. A wise professor once told me, at the ripe age of 20, that moving to New York City after graduating with my Bachelor of Fine Arts degree in Musical Theatre would be a mistake. He told me that as a character actress my time will come and that I am too young to play the roles I am right for. These words were …

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The Field Of Tya On The Soccer Field: Using Drama Strategies To Enhance Youth Soccer Coaching Practices, Brittany Caine Jan 2020

The Field Of Tya On The Soccer Field: Using Drama Strategies To Enhance Youth Soccer Coaching Practices, Brittany Caine

Electronic Theses and Dissertations, 2020-2023

This thesis explores best practices for applying drama strategies to coaching youth soccer. How does drama pedagogy translate to sports? Do drama techniques improve youth soccer? How can using drama- based strategies when coaching youth soccer enhance my own coaching abilities and thus improve the quality of youth soccer instruction and experience? This study applies various drama techniques to pre- written coaching curriculum. This manifested in heavily detailed games, supported by pantomime, storytelling, and narrative exploration, all of which further engaged the children in their soccer exercises. This thesis is supplemented by research on best practices regarding youth soccer, as …

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Lsd1 Promotes Bladder Cancer Progression By Upregulating Lef1 And Enhancing Emt., Qiubo Xie, Tang Tang, Jian Pang, Jing Xu, Xingxia Yang, Linang Wang, Yiqiang Huang, Zhuowei Huang, Gaolei Liu, Dali Tong, Yao Zhang, Luofu Wang, Dianzheng Zhang, Weihua Lan, Qiuli Liu, Jun Jiang Jan 2020

Lsd1 Promotes Bladder Cancer Progression By Upregulating Lef1 And Enhancing Emt., Qiubo Xie, Tang Tang, Jian Pang, Jing Xu, Xingxia Yang, Linang Wang, Yiqiang Huang, Zhuowei Huang, Gaolei Liu, Dali Tong, Yao Zhang, Luofu Wang, Dianzheng Zhang, Weihua Lan, Qiuli Liu, Jun Jiang

PCOM Scholarly Works

Epithelial-to-mesenchymal transition (EMT) is one of the important underlying molecular mechanisms for most types of cancers including bladder cancer. The precise underlying molecular mechanism in EMT-mediated bladder cancer progression is far from completed. LSD1, a histone lysine-specific demethylase, is known to promote cancer cell proliferation, metastasis, and chemoresistance. We found in this study that LSD1 is highly upregulated in bladder cancer specimens, especially those underwent chemotherapy, and the elevated levels of LSD1 are highly associated with bladder cancer grades, metastasis status, and prognosis. Inhibiting or knockdown LSD1 repressed not only EMT process but also cancer progression. Mechanistically, LSD1 complexes with …

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The Vhl/Hif Axis In The Development And Treatment Of Pheochromocytoma/Paraganglioma, Song Peng, Jun Zhang, Xintao Tan, Yiqiang Huang, Jing Xu, Natalie Silk, Dianzheng Zhang, Qiuli Liu, Jun Jiang Jan 2020

The Vhl/Hif Axis In The Development And Treatment Of Pheochromocytoma/Paraganglioma, Song Peng, Jun Zhang, Xintao Tan, Yiqiang Huang, Jing Xu, Natalie Silk, Dianzheng Zhang, Qiuli Liu, Jun Jiang

PCOM Scholarly Works

Pheochromocytomas and paragangliomas (PPGLs) are rare neuroendocrine tumors originating from chromaffin cells in the adrenal medulla (PCCs) or extra-adrenal sympathetic or parasympathetic paraganglia (PGLs). About 40% of PPGLs result from germline mutations and therefore they are highly inheritable. Although dysfunction of any one of a panel of more than 20 genes can lead to PPGLs, mutations in genes involved in the VHL/HIF axis including

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Nations And Markets, Harlan G. Cohen Jan 2020

Nations And Markets, Harlan G. Cohen

Scholarly Works

Economics and security seem increasingly intertwined. Citing national security, states subject foreign investments to new scrutiny, even unwinding mergers like the purchase of Grindr or the creation of TikTok. The provision of 5G has become a diplomatic battleground – Huawei at its center. Meanwhile, states invoke national security to excuse trade wars. The U.S. invoked the GATT national security exception to impose steel and aluminum tariffs, threatening more on automotive parts. Russia invoked that provision to justify its blockade of Ukraine, as did Saudi Arabia and the UAE to excuse theirs of Qatar. And with the spread of COVID-19, states …

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Sintang Dalisay: Reminiscing From The Technical Perspective, D Villanueva Cortezano Jan 2020

Sintang Dalisay: Reminiscing From The Technical Perspective, D Villanueva Cortezano

Perspectives in the Arts and Humanities Asia

No abstract provided.

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Critical Reflection And Pastoral Creativity: The Pilgrim Way Of The People Of God, Christina Kheng Jan 2020

Critical Reflection And Pastoral Creativity: The Pilgrim Way Of The People Of God, Christina Kheng

Asia Pacific Mission Studies

Critical reflection and pastoral creativity are important orientations for mission. They involve being authentically present to a pastoral situation, appropriating relevant data, understanding with mind and heart, evaluating through purifying foundational beliefs, and formulating pastorally-sensitive and creative responses. It is a process that requires pastoral workers to be contemplatives-in-action as lifelong co-learners, connecting more deeply with God, self, others, and the context. This is in turn integral to synodality and communal discernment, and characterizes the pilgrim way of the people of God.

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The Contribution Of Pastoral Institutes For An Inculturated And Contextualized Ministry, Paul B. Steffen Svd Jan 2020

The Contribution Of Pastoral Institutes For An Inculturated And Contextualized Ministry, Paul B. Steffen Svd

Asia Pacific Mission Studies

This article focuses on the contribution of pastoral institutes for an inculturated and contextualized ministry in the non-Western local churches. The treated pastoral institutes in Asia, Africa, Latin America, and Oceania have played an outstanding role in implementing the communion ecclesiology of Vatican II in their respective local churches by moving towards an inculturated Christian faith and church and a contextualized Christian and ecclesial praxis. By following the Vatican II appeal to read and scrutinize the signs of the times, they played a catalytic function in the local non-Western churches to evangelize and to develop a meaningful ministry and participatory …

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Care For Creation And Works Of Mercy, Dennis T. Gonzalez Jan 2020

Care For Creation And Works Of Mercy, Dennis T. Gonzalez

Asia Pacific Mission Studies

In this age of disquiet owing to climate change and contemporary ecological-social calamities, a pastoral Church needs to form servantleaders who can be imaginative practitioners of ecological works of mercy, or who can sow seeds of the New Creation, which reveals the freedom, fidelity, empathy, and eco-social responsibility and maturity of God's sons and daughters in Christ.

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Toward Effective Mission In Asia Pacific Today: Key Orientations For Pastoral Workers And Implications For Formation, Christina Kheng Jan 2020

Toward Effective Mission In Asia Pacific Today: Key Orientations For Pastoral Workers And Implications For Formation, Christina Kheng

Asia Pacific Mission Studies

The current context of Asia Pacific, viewed in the light of foundational principles for the Church’s mission, requires pastoral workers to develop certain key orientations for effective ministry today. These include spiritual depth and maturity, Christ-centeredness, personal integration, meaningful communion with the ecclesial body, proactiveness in mission through life-giving dialogue, and pastoral discernment and creativity. In association with this, greater collaboration is needed in the initial and ongoing formation of pastoral workers so that the Church’s mission in Asia Pacific will be more effective in these times. It is hoped that this article will provide food for thought toward the …

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The Contribution Of Daniel Madigan’S Theological Insights To Interreligious Dialogue In Indonesia, B. Christian Triyudo Prastowo Jan 2020

The Contribution Of Daniel Madigan’S Theological Insights To Interreligious Dialogue In Indonesia, B. Christian Triyudo Prastowo

Asia Pacific Mission Studies

Interreligious dialogue has three interrelated dimensions: an interreligious dimension (mutual relationship), a dialogical dimension (effective communication), and a confessional dimension (deepening of faith and cooperation). This essay explores how Madigan’s theological reflection on dialogue with Muslims fits within those dimensions. Through descriptive-analytical and reflective-dialectical approaches, this essay concludes that the three interrelated dimensions of interreligious dialogue explain the holistic view of Madigan’s theological reflection. It is very useful for Christian-Muslim dialogue in Indonesian context. Two important contributions are the relevance of the dialogue of repentance and the approach of mutual hospitality in theological dialogue with Muslims. This is the kenosis …

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Refining The Data Collection Methodology Of Outdoor Forensic Scenes Involving Scattered Human Remains Using Close-Range Photogrammetry, Megan Mccollum Jan 2020

Refining The Data Collection Methodology Of Outdoor Forensic Scenes Involving Scattered Human Remains Using Close-Range Photogrammetry, Megan Mccollum

Electronic Theses and Dissertations, 2020-2023

The documentation of outdoor forensic crime scenes involving human remains poses multiple challenges to law enforcement officials documenting the context of the scene. More rigorous protocols for the documentation of these scenes are needed, and recent advances in technology open up the possibility of three-dimensional (3D) documentation of the scene. More commonly used in archaeological contexts, close-range photogrammetry (CRP) creates reliable 3D models through triangulation of overlapping points between multiple photographs. This documentation technique allows for the preservation of the entire 3D context and the virtual manipulation without evidence destruction. However, CRP has only been preliminarily used in the field …

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Death In The Land Of Flowers: Environment As Enemy In The Second Seminole War, Nicholas Brown Jan 2020

Death In The Land Of Flowers: Environment As Enemy In The Second Seminole War, Nicholas Brown

Electronic Theses and Dissertations, 2020-2023

This thesis argues that Florida's natural environment was one of the United States Army's most formidable enemies during the Second Seminole War (1835–42), and that environmental factors, more than hostilities from Native peoples themselves, led the United States to abandon the War. Many White soldiers from the North were unprepared to cope with the environmental challenges posed by Florida. In order to build a foundation for this argument, the thesis examines how previous newcomers to Florida dealt with the environment, from the original First Peoples who arrived several thousand years ago, to European explorer/colonizers, to White Americans in the decades …

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Two's Accompany: Understanding Acceptance Through Animation, Brian Phinn Jan 2020

Two's Accompany: Understanding Acceptance Through Animation, Brian Phinn

Electronic Theses and Dissertations, 2020-2023

Animation as a medium has broad appeal based on its ability to convey stories in universal ways. This art form bridges cultural barriers that allow relationships to form through shared interests. Music also shares similar traits. Based on the global understanding of music and its history of use in film, the conclusion is the acceptance of different musical tastes can parallel acceptance of differing ideologies. When clashing ideological beliefs cause societal conflict, it is essential to remember that friendships cultivate through commonalities. The purpose of this study is to create an animated short film that presents the story of two …

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Synthesis Of Ruthenium Bipyridine Conjugated Antibiotic For Fluorescence Lifetime Imaging And Spectroscopy Aided Tracking In Citrus, Ryan Parente Jan 2020

Synthesis Of Ruthenium Bipyridine Conjugated Antibiotic For Fluorescence Lifetime Imaging And Spectroscopy Aided Tracking In Citrus, Ryan Parente

Electronic Theses and Dissertations, 2020-2023

Antibiotic treatment of systemic bacterial plant pathogens is an established practice in many crops; however, in citrus it has only recently become available for growers to utilize against Huanglongbing disease. The preliminary efficacy of these treatments is uncertain due to the inability to track their presence in phloem. The need to monitor their movement in planta, especially their presence and translocation in vascular tissue, is a necessary step in clarifying their effectiveness. Previous work has shown the value of Fluorescence Lifetime Imaging (FLIM) in distinguishing between fluorescent probes and plant tissue autofluorescence, which is normally a barrier in photochemical studies …

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The Effects Of Social Conformity In Human-Robot Interaction, William Volante Jan 2020

The Effects Of Social Conformity In Human-Robot Interaction, William Volante

Electronic Theses and Dissertations, 2020-2023

While previous work has investigated aspects of the robot, the human, and the environment as influential factors in the human-robot relationship, little work has examined the role of social conformity in this relationship. As social conformity has been shown to affect human-human choice, relationships, and trust, there are a-priori reasons to believe that it will play an influential role in human-robot interaction (HRI) scenarios as well. Early research into the influence of social conformity in human-robot interaction (HRI) did not find the effect to be present with robots, however more recent work has adapted the methodological paradigm to find more …

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Development And Characterization Of A Novel Serum Free Human Ipsc Motoneuron-Primary Human Schwann Cell Model Of Myelination, Aakash Patel Jan 2020

Development And Characterization Of A Novel Serum Free Human Ipsc Motoneuron-Primary Human Schwann Cell Model Of Myelination, Aakash Patel

Electronic Theses and Dissertations, 2020-2023

Myelination and node of Ranvier formation play an important role in saltatory conduction of axonal action potentials in the peripheral nervous system (PNS). Degeneration or damage of this myelin can lead to impairment in the conduction of signals by the axons, and cause deficits in sensory and motor function. Currently, animal-based models are the primary method used to study myelination; however, data generated in animal models generally translate poorly to humans, especially as applied to drug discovery. In order to accurately study myelination in humans without having to rely on human testing, an engineered in vitro model of myelination could …

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The Bridwell Quarterly. Issues 8-9, Summer, Fall 2020, Michelle Ried Jan 2020

The Bridwell Quarterly. Issues 8-9, Summer, Fall 2020, Michelle Ried

Bridwell Library Publications

No abstract provided.

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The Role Of Notch1, Il-6 And Mir-146a In Inflammation And Infection In Crohn's Disease Non-Responders To Anti-Tnf-Alpha Therapy, Esra'a Keewan Jan 2020

The Role Of Notch1, Il-6 And Mir-146a In Inflammation And Infection In Crohn's Disease Non-Responders To Anti-Tnf-Alpha Therapy, Esra'a Keewan

Electronic Theses and Dissertations, 2020-2023

Despite the extensive research on Notch signaling involvement in inflammation, its role in macrophage response in autoimmune diseases and defense mechanisms against bacterial infection such as Mycobacterium avium paratuberculosis (MAP) remains unknown. In this study, we investigated the molecular role of Notch-1 signaling and its downstream modulation in the macrophage response during infection and disease treatment. We demonstrated that MAP infection significantly upregulated Notch-1 and IL-6, which hijacked myeloid cell leukemia sequence-1 (MCL)-1 dependent inhibition of apoptosis and caused chronic MAP persistence and significantly led to successive inflammation. Blocking Notch signaling with gamma-secretase inhibitor (DAPT) decreased MAP survival and burden, …

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Metacognitive Monitoring In Test-Taking Situations: A Cross-Cultural Comparison Of College Students, Mariana V.C. Coutinho, Elena Papanastasiou, Stylianou Agni, John M. Vasko, Justin J. Couchman Jan 2020

Metacognitive Monitoring In Test-Taking Situations: A Cross-Cultural Comparison Of College Students, Mariana V.C. Coutinho, Elena Papanastasiou, Stylianou Agni, John M. Vasko, Justin J. Couchman

All Works

© 2020, Eskisehir Osmangazi University. In this study, we examined monitoring accuracy during in class-exams for Emirati, American and Cypriot college students. In experiment 1, 120 students made local, confidence-ratings for each multiple-choice question in a psychology exam and also estimated their performance at the end of the exam. In experiment 2, to investigate the effect of practice in monitoring accuracy, 69 students made confidence judgments in two consecutive exams. In Experiment 3, to evaluate whether rating one's confidence aids exam performance, 172 students completed the exam either with or without providing confidence judgments. In all three cultures, confidence judgments …

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Benzimidazole Containing Acetamide Derivatives Attenuate Neuroinflammation And Oxidative Stress In Ethanol-Induced Neurodegeneration, Muhammad Imran, Lina Tariq Al Kury, Humaira Nadeem, Fawad Ali Shah, Muzaffar Abbas, Shagufta Naz, Arif Ullah Khan, Shupeng Li Jan 2020

Benzimidazole Containing Acetamide Derivatives Attenuate Neuroinflammation And Oxidative Stress In Ethanol-Induced Neurodegeneration, Muhammad Imran, Lina Tariq Al Kury, Humaira Nadeem, Fawad Ali Shah, Muzaffar Abbas, Shagufta Naz, Arif Ullah Khan, Shupeng Li

All Works

© 2020 by the authors. Licensee MDPI, Basel, Switzerland. Oxidative stress-induced neuroinflammation is the prominent feature of neurodegenerative disorders, and is characterized by a gradual decline of structure and function of neurons. Many biochemical events emerge thanks to the result of this neurodegeneration, and ultimately provoke neuroinflammation, activation of microglia, and oxidative stress, leading to neuronal death. This cascade not only explains the complexity of events taking place across different stages, but also depicts the need for more effective therapeutic agents. The present study was designed to investigate the neuroprotective effects of newly synthesized benzimidazole containing acetamide derivatives, 3a (2-(4-methoxyanilino)-N-[1-(4-methylbenzene-1-sulfonyl)-1H-benzimidazol-2-yl] …

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Calcium Homeostasis In Ventricular Myocytes Of Diabetic Cardiomyopathy, Lina T. Al Kury Jan 2020

Calcium Homeostasis In Ventricular Myocytes Of Diabetic Cardiomyopathy, Lina T. Al Kury

All Works

© 2020 Lina T. Al Kury. Diabetes mellitus (DM) is a chronic metabolic disorder commonly characterized by high blood glucose levels, resulting from defects in insulin production or insulin resistance, or both. DM is a leading cause of mortality and morbidity worldwide, with diabetic cardiomyopathy as one of its main complications. It is well established that cardiovascular complications are common in both types of diabetes. Electrical and mechanical problems, resulting in cardiac contractile dysfunction, are considered as the major complications present in diabetic hearts. Inevitably, disturbances in the mechanism(s) of Ca2+ signaling in diabetes have implications for cardiac myocyte contraction. …

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Calcium Signaling In Endocardial And Epicardial Ventricular Myocytes From Streptozotocin-Induced Diabetic Rats, Lina T. Al Kury, Vadym Sydorenko, Manal M.A. Smail, Muhammad A. Qureshi, Anatoly Shmygol, Dimitrios Papandreou, Jaipaul Singh, Frank Christopher Howarth Jan 2020

Calcium Signaling In Endocardial And Epicardial Ventricular Myocytes From Streptozotocin-Induced Diabetic Rats, Lina T. Al Kury, Vadym Sydorenko, Manal M.A. Smail, Muhammad A. Qureshi, Anatoly Shmygol, Dimitrios Papandreou, Jaipaul Singh, Frank Christopher Howarth

All Works

© 2020 The Authors. Journal of Diabetes Investigation published by Asian Association for the Study of Diabetes (AASD) and John Wiley & Sons Australia, Ltd Aims/Introduction: Abnormalities in Ca2+ signaling have a key role in hemodynamic dysfunction in diabetic heart. The purpose of this study was to explore the effects of streptozotocin (STZ)-induced diabetes on Ca2+ signaling in epicardial (EPI) and endocardial (ENDO) cells of the left ventricle after 5–6 months of STZ injection. Materials and Methods: Whole-cell patch clamp was used to measure the L-type Ca2+ channel (LTCC) and Na+/Ca2+ exchanger currents. Fluorescence photometry techniques were used to measure …

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Improving M-Learners' Performance Through Deep Learning Techniques By Leveraging Features Weights, Muhammad Adnan, Asad Habib, Jawad Ashraf, Babar Shah, Gohar Ali Jan 2020

Improving M-Learners' Performance Through Deep Learning Techniques By Leveraging Features Weights, Muhammad Adnan, Asad Habib, Jawad Ashraf, Babar Shah, Gohar Ali

All Works

© 2013 IEEE. Mobile learning (M-learning) has gained tremendous attention in the educational environment in the past decade. For effective M-learning, it is important to create an efficient M-learning model that can identify the exact requirements of mobile learners (M-learners). M-learning model is composed of features that are generated during M-learners' interaction with mobile devices. For an adaptive M-learning model, not only learning features are required, but it is also important to determine how they differ for various M-learners, their weights, and interrelationship. This study proposes a robust and adaptive M-learning model that is based on machine learning and deep …

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Ai Techniques For Covid-19, Adedoyin Ahmed Hussain, Ouns Bouachir, Fadi Al-Turjman, Moayad Aloqaily Jan 2020

Ai Techniques For Covid-19, Adedoyin Ahmed Hussain, Ouns Bouachir, Fadi Al-Turjman, Moayad Aloqaily

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© 2013 IEEE. Artificial Intelligence (AI) intent is to facilitate human limits. It is getting a standpoint on human administrations, filled by the growing availability of restorative clinical data and quick progression of insightful strategies. Motivated by the need to highlight the need for employing AI in battling the COVID-19 Crisis, this survey summarizes the current state of AI applications in clinical administrations while battling COVID-19. Furthermore, we highlight the application of Big Data while understanding this virus. We also overview various intelligence techniques and methods that can be applied to various types of medical information-based pandemic. We classify the …

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Arabic Version Of The Personality Inventory For The Dsm-5 (Pid-5) In A Community Sample Of United Arab Emirates Nationals, Olga Coelho, Rute Pires, Ana Sousa Ferreira, Bruno Gonçalves, Maryam Aljassmi, Joana Stocker Jan 2020

Arabic Version Of The Personality Inventory For The Dsm-5 (Pid-5) In A Community Sample Of United Arab Emirates Nationals, Olga Coelho, Rute Pires, Ana Sousa Ferreira, Bruno Gonçalves, Maryam Aljassmi, Joana Stocker

All Works

© 2020 Coelho et al. Background: Section III of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5) proposes a model for conceptualizing personality disorders in which they are characterized by impairments in personality functioning and maladaptive personality traits. The Personality Inventory for DSM-5 (PID-5) is a self-report measure that assesses the presence and severity of these maladaptive personality traits. Objective: The current study examined the reliability and validity of the Arabic version of the Personality Inventory for DSM-5 (PID-5) to measure maladaptive personality traits in the Emirati population of the United Arab Emirates. Methods: The Arabic version of the …

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Both Maternal And Embryonic Exposure To Mild Hypoxia Influence Embryonic Development Of The Intertidal Gastropod Littorina Littorea (Linnaeus, 1758)., James C.S. Mccoy, John I. Spicer, Oliver Tills, Simon D. Rundle Jan 2020

Both Maternal And Embryonic Exposure To Mild Hypoxia Influence Embryonic Development Of The Intertidal Gastropod Littorina Littorea (Linnaeus, 1758)., James C.S. Mccoy, John I. Spicer, Oliver Tills, Simon D. Rundle

School of Biological and Marine Sciences

There is growing evidence that maternal exposure to environmental stressors can alter offspring phenotype and increase fitness. Here, we investigate the relative and combined effects of maternal and developmental exposure to mild hypoxia (65% and 74% air saturation respectively) on the growth and development of embryos of the marine gastropod Littorina littorea. Differences in embryo morphological traits were driven by the developmental environment, whereas the maternal environment and interactive effects of maternal and developmental environment were the main driver of differences in the timing of developmental events. While developmental exposure to mild hypoxia significantly increased the area of an important …

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