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2020

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Active Learning For Auditory Hierarchy, William Coleman, Sarah Jane Delany, Charlie Cullen, Ming Yan Jan 2020

Active Learning For Auditory Hierarchy, William Coleman, Sarah Jane Delany, Charlie Cullen, Ming Yan

Conference papers

Much audio content today is rendered as a static stereo mix: fundamentally a fixed single entity. Object-based audio envisages the delivery of sound content using a collection of individual sound ‘objects’ controlled by accompanying metadata. This offers potential for audio to be delivered in a dynamic manner providing enhanced audio for consumers. One example of such treatment is the concept of applying varying levels of data compression to sound objects thereby reducing the volume of data to be transmitted in limited bandwidth situations. This application motivates the ability to accurately classify objects in terms of their ‘hierarchy’. That is, whether …

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Making Meaning : Death, Dignity, And Dasein In Kazuo Ishiguro’S Never Let Me Go, Angel Katrina Tuohy Jan 2020

Making Meaning : Death, Dignity, And Dasein In Kazuo Ishiguro’S Never Let Me Go, Angel Katrina Tuohy

Theses, Dissertations and Culminating Projects

This thesis explores Kazuo Ishiguro’s 2005 novel Never Let Me Go, with a focus on the way the novel considers large questions concerning the “meaning” of human life and the nature of “human condition” as Ishiguro calls it in interviews discussing his novel, using language and terminology provided by phenomenologist and philosopher Martin Heidegger in his seminal work Being and Time. This thesis builds on these questions to consider the complex ways that the concept of “dignity” as shown through the experiences of clones who have socially predetermined lifespans complicates issues surrounding the inevitability of death, the uncanniness of …

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Environmental And Trophic Factors That Influence The Prevalence Of Gonionemus Vertens In The Northeastern United States, Matthew Rigby Jan 2020

Environmental And Trophic Factors That Influence The Prevalence Of Gonionemus Vertens In The Northeastern United States, Matthew Rigby

Theses, Dissertations and Culminating Projects

Gonionemus vertens, often referred to as the clinging jellyfish, is an invasive hydrozoan first documented in 2016 in New Jersey. Populations of the adult medusa stage bloom in May and continue to persist through the middle of July, during which time it is of particular concern from a public health standpoint. G. vertens 'clings' to sea grasses and other submerged aquatic vegetation in shallow coastal waters, which are highly utilized for recreational activities, and its sting is highly toxic, which can hospitalize victims for days with both physical and psychiatric symptoms. Encounters with highly toxic G. vertens are, unfortunately, becoming …

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A Salty Compromise: The Behavioral Response Of Red-Backed Salamanders (Plethodon Cinereus) To Different Concentrations Of Nacl, A Prevalent Road Deicer, Randolph Viola Jan 2020

A Salty Compromise: The Behavioral Response Of Red-Backed Salamanders (Plethodon Cinereus) To Different Concentrations Of Nacl, A Prevalent Road Deicer, Randolph Viola

Theses, Dissertations and Culminating Projects

Many amphibians are bound to a nearby freshwater source such as lakes and vernal pools. Often times, this is because they are fully aquatic; if they are partially terrestrial, they still need freshwater bodies to lay their eggs in a suitable environment. With the constant use of road salt as a deicer during snowing periods, the subsequent runoff has negatively altered nearby soil and water sources. Amphibians, with their permeable skin, are at great risk of desiccation if exposed to a hyperosmotic environment caused by this application. However, some plethodontid salamanders deviate from this restrictive norm by living as dedicated …

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The Disappearing Act: How To Prevent The Decline Of Black Farmers In The United States, Jordan M. Jennings Jan 2020

The Disappearing Act: How To Prevent The Decline Of Black Farmers In The United States, Jordan M. Jennings

Kentucky Journal of Equine, Agriculture, & Natural Resources Law

No abstract provided.

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Ethanol Induced Neurotoxicity Through Dysregulation Of Ampk In A Fetal Alcohol Syndrome Model, Jessica Gebhardt Jan 2020

Ethanol Induced Neurotoxicity Through Dysregulation Of Ampk In A Fetal Alcohol Syndrome Model, Jessica Gebhardt

Theses and Dissertations--Medical Sciences

Ethanol consumption during pregnancy is rising in the U.S., including the rate of binge drinking. It is reported around 1 in 27 women engage in binge drinking activities while pregnant. The third trimester is a sensitive period of neuronal growth in which ethanol induced neurotoxicity can cause many harmful effects including Fetal Alcohol Spectrum Disorders. It has been shown that ethanol decreases the activity of AMPK through increasing lipid peroxidation, both of which are correlated to neurotoxicity. AICAR is a synthetic analog of AMP which significantly increases AMPK activity and may have beneficial effects in an organotypic hippocampal model of …

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Bulletin: General Catalog Issue 2020-2021, Portland State University Jan 2020

Bulletin: General Catalog Issue 2020-2021, Portland State University

Bulletin & Curriculum Change Documents

Volume 1 - Programs is available via the Download option, Volume 2 - Courses is available in the Additional Files below

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Novel Substrate-Free Cholinesterase Based Sensing Of Organophosphorus Compounds, Hailey J. Marini Jan 2020

Novel Substrate-Free Cholinesterase Based Sensing Of Organophosphorus Compounds, Hailey J. Marini

Legacy Theses & Dissertations (2009 - 2024)

The increasing concerns of chemical weapons used by terrorists is growing, creating a need for infield detection methods that can rapidly detect these compounds that are a major health concern for civilians and military personnel. Displacement is a novel concept for the detection of cholinesterase inhibitors, including organophosphorus compounds, that could replace the classical instrumentation methods currently being used for diagnostics.

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Alterations In Corticotropin-Releasing Factor Receptor Type 1 In The Hypothalamus And Preoptic Area During The Postpartum Period, Rose Ann M. De Guzman Jan 2020

Alterations In Corticotropin-Releasing Factor Receptor Type 1 In The Hypothalamus And Preoptic Area During The Postpartum Period, Rose Ann M. De Guzman

Legacy Theses & Dissertations (2009 - 2024)

Despite the apparent sex difference in prevalence of anxiety in humans, pre-clinical studies that have led to anxiolytic drug discoveries between 1960 and 2012 used male animals and approximately 6% of 10,000 studies used female animals. The generalizability of the efficacy of these drugs to both sexes may be limited if data derived are predominantly based on the male brain. The purpose of this dissertation, therefore, was to investigate potential underlying neuronal mechanisms that could be contributing to the sex differences in stress-related mood disorder prevalence and to focus on shedding light on female brains.

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Molecular Mechanisms Shaping Host Range Of A Vector-Borne Pathogen, Thomas Macgregor Hart Jan 2020

Molecular Mechanisms Shaping Host Range Of A Vector-Borne Pathogen, Thomas Macgregor Hart

Legacy Theses & Dissertations (2009 - 2024)

Vector-borne diseases, such as Lyme disease caused by Borrelia burgdorferi sensu lato (Bbsl), have narrow host ranges and are apt models to study host-microparasite coevolution. Some species and strains of Lyme borreliae (LB) are specialists, infecting only mammalian or only avian hosts (ex. Borrelia afzelii and B. garinii, respectively), while others are generalists and infect both hosts (ex. B. burgdorferi). Such host tropisms are hypothesized to be partially shaped by the ability of these pathogens evade host immune defenses, such as complement. Complement is a first line host defense against invading pathogens that kills LB in vitro and inhibits spirochete …

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Cholinesterase Based System For Fentanyl Detection, Alyssa Shoemaker Jan 2020

Cholinesterase Based System For Fentanyl Detection, Alyssa Shoemaker

Legacy Theses & Dissertations (2009 - 2024)

Opioids and other illicit drugs have become a very prevalent problem across the world, especially in the United States. In fact, every day more than 130 people die from an opioid overdose. Despite many public warnings explaining the risks of opioid and drug use, the epidemic has continued to grow. As illicit drugs are becoming more rampant in society, law enforcement officers need a reliable, rapid, and non-invasive method to detects when someone may be on drugs, for example while driving, and to assess unknown powders or substances when presented at a crime scene containing drugs. Currently, at traffic stops …

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Synaptic Homeostasis At The Drosophila Neuromuscular Junction, Andrew Powers Jan 2020

Synaptic Homeostasis At The Drosophila Neuromuscular Junction, Andrew Powers

Legacy Theses & Dissertations (2009 - 2024)

Synaptic homeostasis is a specialized form of synaptic plasticity that maintains synaptic strength within normal parameters. The synapse must regulate its activity both during growth and in response to repeated stimulation. Much of the study of synaptic homeostasis has focused on presynaptic modifications to the quantal content. There is, however, evidence of postsynaptic regulation as an important form of synaptic homeostasis. To further investigate the ability of the synapse to make homeostatic modifications to its function we utilized the Drosophila neuromuscular junction (NMJ) as our model system. To examine the regulation of excitation at the NMJ during growth we observed …

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The Stromal Response In Salivary Gland Injury, Kevin O'Keefe Jan 2020

The Stromal Response In Salivary Gland Injury, Kevin O'Keefe

Legacy Theses & Dissertations (2009 - 2024)

Abstract

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Identification And Analysis Of Body Fluid Traces For Forensic Purposes Using Vibrational Spectroscopy And Chemometrics, Ewelina M. Mistek-Morabito Jan 2020

Identification And Analysis Of Body Fluid Traces For Forensic Purposes Using Vibrational Spectroscopy And Chemometrics, Ewelina M. Mistek-Morabito

Legacy Theses & Dissertations (2009 - 2024)

Recent years have seen a large expansion in the forensic field due to the introduction of novel analytical techniques. Body fluids are an extremely important type of evidence at crime scenes and the main source of DNA. Most current methods for the identification and examination of body fluid traces require chemical treatment and are therefore destructive to the sample. Thus, new methods that are nondestructive and provide rapid results with statistical confidence are desirable. Such methods could eliminate noninformative traces and allow investigators to focus on more valuable pieces of evidence. The ultimate goal of this research is to develop …

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Tfap2e/Ap-2e Is A Transcriptional Regulator Controlling Neuronal Identity And Circuitry Formation In The Mouse Accessory Olfactory System, Jennifer M. Lin Jan 2020

Tfap2e/Ap-2e Is A Transcriptional Regulator Controlling Neuronal Identity And Circuitry Formation In The Mouse Accessory Olfactory System, Jennifer M. Lin

Legacy Theses & Dissertations (2009 - 2024)

Developmental progression is driven by specific spatiotemporal gene expression, which give rise to consistently patterned organisms despite environmental and genetic variation. The specific activation of robust gene regulatory networks that define tissue structure and individual cellular identity are necessary for tissue and cell specific programs to be activated. Cellular specification is guided by the interplay of intrinsic and extrinsic signals at specific developmental timepoints. The molecular mechanisms underlying the acquisition and maintenance of individual cellular identity remains a fundamental question across biological systems. Understanding the regulatory networks controlling the acquisition of neuronal identity, diversity, and connectivity in the formation of …

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Do Distractor Suppression And Learning Intentionality Contribute To The Attentional Boost Effect?, Stephanie C. Crocco Jan 2020

Do Distractor Suppression And Learning Intentionality Contribute To The Attentional Boost Effect?, Stephanie C. Crocco

Legacy Theses & Dissertations (2009 - 2024)

In the Attentional Boost Effect (ABE), a target-detection response enhances memory for simultaneously presented unrelated stimuli (Swallow & Jiang, 2010; see Swallow & Jiang, 2013 for a review). In two experiments, participants read aloud words simultaneously presented with a dot. Trials were presented every 1150 ms (Experiment 1) or every 2200 ms (Experiment 2). In a divided attention (DA) task, participants made a key-press to dots of a specific color. In a full attention (FA) task, they only read the words aloud while ignoring all dots. Under either intentional or incidental learning instructions, the DA task included Target words, and …

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Against Bloom: A Defense Of Smithian Fellow-Feeling, Damian Thomas Masterson Jan 2020

Against Bloom: A Defense Of Smithian Fellow-Feeling, Damian Thomas Masterson

Legacy Theses & Dissertations (2009 - 2024)

In his 2016 book, Against Empathy: The Case for Rational Compassion, Paul Bloom argues that “if we want to be good caring people, if we want to make the world a better place, then we are better off without empathy.” I’ve specifically chosen this formulation of Bloom’s position because it gets at the issue I will most directly challenge him on - that we would, or even could, be better off without empathy. The position I will defend is that our empathy plays an indispensable role in the development of our moral conscience, and an ongoing role in the cultivation …

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Vertiginous Space And Blank Topographies : The Narrative Landscapes Of Possession And Annihilation In J. M. Coetzee's Early Novels, Leah Slocum Jan 2020

Vertiginous Space And Blank Topographies : The Narrative Landscapes Of Possession And Annihilation In J. M. Coetzee's Early Novels, Leah Slocum

Legacy Theses & Dissertations (2009 - 2024)

This thesis examines the first three novels published by the South African author J.M Coetzee: Dusklands (1974), In the Heart of the Country (1977), and Waiting for the Barbarians (1980). My analyses is structured around how the narrators engage with a vast and threatening landscape in ways that seek to validate an illusion of spatial control and mastery and uphold the colonial metaphor of emptied landscapes. Although only Jacobus in Dusklands embodies the archetypal explorer that “penetrates” the heart of darkness, his counterparts in the next two novels uphold the same kind of self-mythologizing process in which their desire to …

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The Role Of Progesterone Receptor In The Postnatal Development Of The Dentate Gyrus And Episodic-Like Memory, Andrew James Newell Jan 2020

The Role Of Progesterone Receptor In The Postnatal Development Of The Dentate Gyrus And Episodic-Like Memory, Andrew James Newell

Legacy Theses & Dissertations (2009 - 2024)

The hippocampus is a critical structure for the encoding and retrieval of declarative memories in humans, including episodic-memories. In rodents the steroid hormone receptor progesterone receptor (PR) is expressed in the dentate gyrus (DG) of the hippocampus during the postnatal period, a key stage in development of DG cytoarchitecture and connectivity. During the first postnatal week, the main cortical input to the hippocampal circuit, the perforant path, innervates the molecular layer (MOL) of the DG and forms temporary initial synaptic connections with pioneer neurons. By the third postnatal week, long-term synapses have been established with granule cells, the principle neurons …

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Effect Of Draxin Manipulation On Btbr Mouse Brain And Behavior, Adam Blau Jan 2020

Effect Of Draxin Manipulation On Btbr Mouse Brain And Behavior, Adam Blau

Legacy Theses & Dissertations (2009 - 2024)

Autism Spectrum Disorder (ASD) is known for distinct behavioral phenotypes such as a preference for repetitive activities and difficulty in socialization. However, little is known about what might cause ASD. Current evidence implicates genetics as playing a substantial role in ASD. Mouse models, such as BTBR T+ Itpr3tf/J (BTBR) inbred mice, are an invaluable resource for ASD research, as they allow the investigation of both genetics and behavior in parallel. BTBR mice are of interest due to their reduced hippocampal commissure (HC) and absent corpus callosum (CC), along with increased exploratory activity, decreased anxiety, reduced sociability, and increased repetitive self-grooming …

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The Role Of Gaba Signaling In Gnrh Neuron Migration And Function, Tyler Mitchell Jan 2020

The Role Of Gaba Signaling In Gnrh Neuron Migration And Function, Tyler Mitchell

Legacy Theses & Dissertations (2009 - 2024)

Gonadotropin-releasing hormone (GnRH) neurons are key regulators of sexual development and reproduction of animals from ascidians to vertebrates. Gamma-amino butyric acid (GABA) has been implicated, in literature, as one of the major players in the regulating GnRH neuronal development and neuronal activity. GABA usually acts as an inhibitory neurotransmitter, however, in GnRH neurons it has been described as an excitatory stimulus in different animal models. In my master thesis I will present and discuss a series of scientific articles on this topic to summarize the current understanding of how GABA signaling affects GnRH neuronal development and physiological activity in reproduction.

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Implicit Sense Of Gratification : A New Lens On Academic Intrinsic Motivation, Haiyang Su Jan 2020

Implicit Sense Of Gratification : A New Lens On Academic Intrinsic Motivation, Haiyang Su

Legacy Theses & Dissertations (2009 - 2024)

The main purpose of this study was to explore the relationship among key concepts from three motivation theories— mastery and performance goal orientation from Achievement Goal Theory (AGT, Elliot & McGregor, 2001), proximal and distal goal setting from Goal Setting Theory (GST; Locke & Latham, 1990), and academic intrinsic motivation based on the Self-Determination Theory (SDT; Deci & Ryan, 1985). The study also examined moderating effects by gender and grade level difference on the relationship between proximal goal setting and academic intrinsic motivation. Implicit sense of gratification, a new concept proposed in this study, was used to test the mediation …

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Elemental Composition And Arsenic Speciation Analysis Of Processed Seafood Products Using Atomic Spectrometric Techniques, Austin A. Roberts Jan 2020

Elemental Composition And Arsenic Speciation Analysis Of Processed Seafood Products Using Atomic Spectrometric Techniques, Austin A. Roberts

Legacy Theses & Dissertations (2009 - 2024)

Arsenic (As) is a widely known toxic element that is highly ubiquitous and has been detected in soil, sediment, naturals waters, the atmosphere, and in organisms of the 5 kingdoms. The toxicity of As however, is dependent on the molecular form in which it takes as well as the route of exposure. For the general population, exposure to As mainly takes place via ingestion of food and water, which have led to numerous studies investigating As and it’s various species in these matrices. Seafood is one of the major sources of dietary exposure to As and has thus led to …

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Economy, Exchange, And Political Power At Lomas Entierros, Central Pacific Costa Rica, Yajaira Maria Nunez-Cortes Jan 2020

Economy, Exchange, And Political Power At Lomas Entierros, Central Pacific Costa Rica, Yajaira Maria Nunez-Cortes

Legacy Theses & Dissertations (2009 - 2024)

Archaeology's focus on long-term transformations in society provides a unique perspective to understand the rise and development of political and economic power and its effects on different groups of society. Comparative archaeological analyses of complex societies have demonstrated that there is a high degree of variability in the expression of such complexity, as well as in the processes that led to its emergence around the world. Within this broader context, this study focuses on intra-site and household economy patterns to gain insight into the sources of political and economic power, and reveal other forms of organization that may differ from …

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A Hunger For Justice : Everyday Forms Of Latinx Resistance In New York State's Capital Region, Cassandra Andrusz- Ho Ching Jan 2020

A Hunger For Justice : Everyday Forms Of Latinx Resistance In New York State's Capital Region, Cassandra Andrusz- Ho Ching

Legacy Theses & Dissertations (2009 - 2024)

Low-income racialized communities have always disproportionately struggled with food system inequities. However, after the 2008 financial crisis, conditions have become more precarious, especially in Latinx communities. This context has resulted in intensified food system inequities, manifesting as food insecurity, high food pricing, inconsistent and partial food programming, diet related diseases, low wages, worker and environmental rights abuses. This dissertation examines how low-income Latinx communities, respond to these intensified inequities in the New York State Capital Region from 2008-2018. Through qualitative research, interviews and observations, I assess the nature and context of everyday practices that undermine or resist food system inequities, …

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The Brain's Large-Scale Electrophysiological Signals : Fundamental Attributes And Neurosurgical Applications, Mohammad Amin N/A Nourmohammadi Jan 2020

The Brain's Large-Scale Electrophysiological Signals : Fundamental Attributes And Neurosurgical Applications, Mohammad Amin N/A Nourmohammadi

Legacy Theses & Dissertations (2009 - 2024)

Brain’s electrophysiological signals are most certainly the ultimate source for studying the sophisticated neural network inside our cranium. The unparalleled complexity of these biosignalsis the quintessential manifestation of their underlying complicated neurophysiological processes. Studying brain signals on the cellular level provides valuable information regarding the brain’s electrophysiology on the small-scale. However, it is the remarkable network in the large-scale that gives rise to the brain’s extraordinary attributes and exceptional capabilities—perception, cognition, computation, and consciousness are all the emergent byproducts of the dynamic neuronal interactions on the network level. In this sense, the large-scale electrophysiological signals, recorded from the surface of …

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The Dysregulation Of Circadian Rhythms And Its Relation To Hippocampal Neurodegenerative Disease, John Patrick Mccauley Jan 2020

The Dysregulation Of Circadian Rhythms And Its Relation To Hippocampal Neurodegenerative Disease, John Patrick Mccauley

Legacy Theses & Dissertations (2009 - 2024)

Circadian rhythms modulate body temperature, sleep-wake cycles and cognitive functions like learning and memory. Interestingly, patients suffering from neurodegenerative disease like Alzheimer’s disease and brain insults like traumatic brain injury experience dysregulated circadian rhythms and learning and memory deficiencies as a symptom. The core molecular machinery that establishes these rhythms relies on the activation of positive and negative transcriptional-translational feedback loops within the hypothalamic suprachiasmatic nucleus (SCN). Subordinate circadian oscillators distributed throughout the peripheral and central nervous system follow the rhythmic activity of the SCN. One of these, the hippocampus, is mostly involved in regulating memory formation and recall. Experimental …

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Real Men Don't Get Lipos : Gender, Political Economy, And Biomedicine In Colombia's Male Beauty Industry, Jose Alejandro Arango-Londono Jan 2020

Real Men Don't Get Lipos : Gender, Political Economy, And Biomedicine In Colombia's Male Beauty Industry, Jose Alejandro Arango-Londono

Legacy Theses & Dissertations (2009 - 2024)

The last few years in Colombia have seen the rise and expansion of male beauty industry. Such growth seems to suggest a shift from entrenched gendered ideas as well as new markets and economic opportunities to pursue. This dissertation is the result of eighteen months of ethnographic fieldwork in Cali, Colombia focusing on how the development of male beauty has emerged in a context that is profoundly shaped by the legacy of armed conflict and drug-trafficking. The expansion of male beauty industry flourishes in a political and economic moment in Colombia where neoliberal policies are prevalent in the state’s agenda.

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Displacement Using Fentanyl And Bullet Analysis Using Atomic Absorption Spectroscopy, Henry Hance Jan 2020

Displacement Using Fentanyl And Bullet Analysis Using Atomic Absorption Spectroscopy, Henry Hance

Legacy Theses & Dissertations (2009 - 2024)

Opioids are substances that bind to opioid receptors in the central nervous system and can be endogenous, naturally occurring opium alkaloids derived from opium poppy or semi-synthetic and or synthetic compounds.1 Fentanyl is a synthetic opioid that has flooded the US market in the last decade. Synthetic opioid deaths increased by 100% from 2015 to 2016.2 The synthetic opioid is still used to treat severe chronic pain and during surgeries as an anesthetic, but has flooded the black market through illegal means. Fentanyl is prescribed in the forms of patches and lozenges, but can be abused and illegal sold in …

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Assessment Of Food Safety Compliance To Federal, State And Local Regulations Within Nys Capital Region Farmers Markets : An Investigation Of Current Facilitators, Barriers, And Future Opportunities To Increase Food Safety, Patricia Ann Miller Jan 2020

Assessment Of Food Safety Compliance To Federal, State And Local Regulations Within Nys Capital Region Farmers Markets : An Investigation Of Current Facilitators, Barriers, And Future Opportunities To Increase Food Safety, Patricia Ann Miller

Legacy Theses & Dissertations (2009 - 2024)

Within the United States there are over 8,000 farmers markets, that sell directly to consumers. New York State has the second-largest number of markets, at 637, with the capital region host to 114 markets. Over the years the selections of offerings have grown to include not only produce but ready-to-eat foods, eggs, dairy products, crafts, beer, and wine. The increasing popularity of farmers markets coupled with inadequate regulatory oversight of these markets, can contribute to incidences of foodborne illnesses. The Centers for Disease Control identified 95 foodborne illness outbreaks in the United States potentially associated with fairs, festivals, and temporary …

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