Digital Commons Network^™

The Professional Responsibility Case For Valid And Nondiscriminatory Bar Exams, Joan W. Howarth

Scholarly Works

Title VII protects against workplace discrimination in part through the scrutiny of employment tests whose results differ based on race, gender, or ethnicity. Such tests are said to have a disparate impact, and their use is illegal unless their validity can be established. Validity means that the test is job-related and measures what it purports to measure. Further, under Title VII, even a valid employment test with a disparate impact could be struck down if less discriminatory alternatives exist.

Licensing tests, including bar exams, have been found to be outside these Title VII protections. But the nondiscrimination values that animate …

Justice In A Brave New World?, Jean R. Sternlight

Scholarly Works

As science fiction has become reality, we should consider the implications of our new technologies for our system of justice. In addition to DNA, we are now regularly using cameras, geo-tracking, facial recognition software, brain scans, computers, and much more to discern and record our physical and mental surroundings. Existing technology and more we cannot yet imagine will increasingly take the place of often unreliable evidence, such as that provided by eyewitnesses. Yet, we have given far too little thought as to how these advances should impact our civil and criminal dispute resolution systems.

Historically, many justice systems have emphasized …

Training Law Students To Maintain Civility In Their Law Practices As A Way To Improve Public Discourse, Nancy B. Rapoport

Scholarly Works

Our current social discourse is broken. Not only have we resorted to name-calling instead of reasoned discussion, but we have also resorted to the fundamental attribution error: we attribute bad motives to people with whose positions we disagree rather than starting with the presumption that, perhaps, buried deep within their positions could be a grain of truth. As Yoni Appelbaum observed in a recent article in The Atlantic, "Recent research by political scientists at Vanderbilt University and other institutions has found both Republicans and Democrats distressingly willing to dehumanize members of the opposite party."' We need to find a …

Diploma Privilege And The Constitution, Claudia Angelos, Sara Berman, Mary Lu Bilek, Carol M. Chomsky, Andrea Anne Curcio, Marsha Griggs, Joan W. Howarth, Eileen R. Kaufman, Deborah Jones Merritt, Patricia Salkin, Judith W. Wegner

Scholarly Works

The COVID-19 pandemic and resulting shutdowns are affecting every aspect of society. The legal profession and the justice system have been profoundly disrupted at precisely the time when there is an unprecedented need for legal services to deal with a host of legal issues generated by the pandemic, including disaster relief, health law, insurance, labor law, criminal justice, domestic violence, and civil rights. The need for lawyers to address these issues is great but the prospect of licensing new lawyers is challenging due to the serious health consequences of administering the bar examination during the pandemic.

State Supreme Courts are …

John And Molly: A Methodist Mismarriage, Samuel J. Rogal

The Asbury Journal

No abstract provided.

Powerlessness And A Social Imaginary In The Philippines: A Case Study On Bahala Na, Yohan Hong

The Asbury Journal

No abstract provided.

Associations Between Dietary Fat Quality And Cognitive Function Among Adults: The Hispanic Community Health Study/ Study Of Latinos, Nicole Karazurna

Master's Theses and Capstones

Individual fatty acids (FA) within dietary fat classes [saturated (SFA), monounsaturated (MUFA), polyunsaturated (PUFA), and trans FA (TFA)] may deferentially affect risk of cognitive impairment. This has received little attention by previous studies of diet and cognitive function, and few studies are available among Hispanic/Latinos. We quantified the associations of dietary FA (DFA) patterns with cognitive function among Hispanic/Latinos in the US. In a cross-sectional analysis of participants of the Hispanic Community Health Study/ Study of Latinos, recruited from 2008-11 (n=7842, mean age 55 y, 62% female). Dietary data are from two 24-hr recalls; the National Cancer Institute method estimated …

Dustbowl Waters: Doctrinal And Legislative Solutions To Save The Ogallala Aquifer Before Both Time And Water Run Out, Warigia M. Bowman

University of Colorado Law Review

Eighty-three years after the Dust Bowl, residents of America's High Plains face a dire threat: their primary aquifer faces depletion, and entire sections of the country are set to run out of groundwater by the end of the century or sooner.

The Ogallala Aquifer provides a significant amount of America's agricultural irrigation water and is a primary source of drinking water for Colorado, Kansas, Nebraska, New Mexico, Oklahoma, South Dakota, Texas, and Wyoming.

This Article argues that policymakers should slow the Aquifer's depletion rate by implementing changes to irrigation technology, crop choice, consumer behavior, legal doctrine, and legislation. This Article …

Survey And Excavation Of Properties Associated With Squire Brockman, An Early Historic Resident, Blacksmith And Mechanic At The Historic Dearfield Townsite And National Register Of Historic Places District In 2020: Report To The Colorado State Historic Preservation Fund (Shf Grant Project #2020-M2-003), Robert H. Brunswig

Dearfield Archaeological Reports

No abstract provided.

The Politics Of Regulatory Enforcement And Compliance: Theorizing And Operationalizing Political Influences, Jodi L. Short

Faculty Scholarship

There is broad consensus in the literature on regulatory enforcement and compliance that politics matters. However, there is little scholarly convergence on what politics is or rigorous theorization and empirical testing of how politics matters. Many enforcement and compliance studies omit political variables altogether. Among those that address political influences on regulatory outcomes, politics has been defined in myriad ways and, too often, left undefined. Even when political constructs are explicitly operationalized, the mechanisms by which they influence regulatory outcomes are thinly hypothesized or simply ignored. If politics is truly as important to enforcement and compliance outcomes as everyone in …

The Independence Effects Of Gravitational And Inertial Forces On Gait Transitions In Humans, Nathan Frakes

Cal Poly Humboldt theses and projects

The Dynamic Similarity hypothesis suggests gravitational and inertial forces plays a role in determining preferred transition speed (PTS) for walk to run transitions (WRT) and run to walk transitions (RWT), and that humans prefer to transition gait when the ratio of inertial force (IF) to gravitational force (GF) (i.e. Froude #) is ~0.5. Purpose: To investigate the effect of gravitational and inertial forces on PTS, Froude # (Fr) and kinematics for both WRT and RWT. Methods: Twelve healthy adults (9 M, 3 F) performed WRT and RWT trials on a treadmill across seven combinations of altered body weight (BW) and …

Justice V. Prevention: A Nuanced Approach To International Criminal Prosecutions, Peter R. Grenzow

Minnesota Journal of International Law, Vols. 28:2 onward (2019-present)

One of the principal purposes of the Rome Statute is the prevention of future international crimes. To achieve this goal, the International Criminal Court (ICC) must consider the effects that its law enforcement measures will have on the commission of atrocities in a situation under review. This article responds to the need for context-specific empirical research elucidating the effects of ICC interventions. Reviewing evidence from the situations subject to ICC intervention over the past two decades and advances in social psychology and neuroscience, this article offers a number of factors the ICC should take into account when deciding whether to …

Unravelling Socio-Economic And Ecological Distribution Conflicts In Ship-Breaking In Bangladesh For Addressing Negative Externalities In Law And Policy Making, Ishtiaque Ahmed

Minnesota Journal of International Law, Vols. 28:2 onward (2019-present)

Ship-breaking is widely known as a colossally dangerous and polluting activity. Bangladesh has emerged as the market leader in ship-breaking, producing the highest amount of steel from recycling End of Life ships owned by global owners. Economic contribution of ship-breaking in Bangladesh has been well documented from the report published under the auspicious of the Government and the International Governmental Agencies, but significant controversy exists to prove those data. In absence of detailed scientific investigation, uncertainty remains about the extent this industry is adversely impacting the coastal environments of Bangladesh. Notably, there is a huge polarization of data, and claim …

Dynamic Prostatic And Laser-Ablated Lesion Volume Change After Transperineal Laser Ablation In Canine: Preliminary Observation And Its Clinical Significance., Rui-Qing Liu, Ji-Bin Liu, Shao-Bo Duan, Si-Guo Cheng, Zhi-Yang Chang, Hui-Cun Cao, Guang-Shao Cao, Ya-Qiong Li, Na Li, Lian-Zhong Zhang

Department of Radiology Faculty Papers

AIM: The purpose of this study is to observe the volume change of prostate and laser-ablated lesions in the canine and to explore the mechanism and clinical significance through histopathology.

MATERIALS AND METHODS: Transperineal laser ablation (TPLA) was performed under the guidance of transrectal ultrasound (TRUS) in eight canines. Two canines were sacrificed 1 day and 1 week after TPLA, respectively. The remaining six canines were sacrificed after finishing transrectal contrast-enhanced ultrasound (TR-CEUS) at three phases.

RESULTS: The prostatic volumes immediately following TPLA and 1 week later were larger than before TPLA (20.1 ± 3.9 vs 17.1 ± 3.8 ml; …

Table Of Contents, Seattle University Law Review

Seattle University Law Review

Table of Contents

5-Fluorocytosine Resistance Is Associated With Hypermutation And Alterations In Capsule Biosynthesis In Cryptococcus, R. Blake Billmyre, Shelly Applen Clancey, Lucy X. Li, Tamara L. Doering, Joseph Heitman

Open Access Publications

No abstract provided.

L-Plastin Deficiency Produces Increased Trabecular Bone Due To Attenuation Of Sealing Ring Formation And Osteoclast Dysfunction, Meenakshi A. Chellaiah, Megan C. Moorer, Sunipa Majumdar, Hanan Aljohani, Sharon C. Morley, Vanessa Yingling, Joseph P. Stains

Open Access Publications

No abstract provided.

Protective Role Of Brain Derived Neurotrophic Factor (Bdnf) In Obstructive Sleep Apnea Syndrome (Osas) Patients, Krisstopher Richard Flores, Fausta Viccaro, Mauro Aquilini, Stefania Scarpino, Francesco Ronchetti, Rita Mancini, Arianna Di Napoli, Davide Scozzi, Alberto Ricci

Open Access Publications

Obstructive sleep apnea syndrome (OSAS) is a common disorder characterized by repeated episodes of upper airways collapse during the sleep. The following intermittent hypoxia triggers a state of chronic inflammation, which also interests the nervous system leading to neuronal damage and increased risk of cognitive impairment. Brain derived neurotrophic factor (BDNF) is a growth factor often associated with neuroplasticity and neuroprotection whose levels increase in several condition associated with neuronal damage. However, whether patients affected by OSAS have altered BDNF levels and whether such alteration may be reflective of their cognitive impairment is still controversial. Here we show that, when …

Gene-By-Gene Interactions Associated With The Risk Of Conotruncal Heart Defects, Chen Lyu, Daniel M Webber, Stewart L Macleod, Charlotte A Hobbs, Ming Li, National Birth Defects Prevention Study

Open Access Publications

BACKGROUND: The development of conotruncal heart defects (CTDs) involves a complex relationship among genetic variants and maternal lifestyle factors. In this article, we focused on the interactions between 13 candidate genes within folate, homocysteine, and transsulfuration pathways for potential association with CTD risk.

METHODS: Targeted sequencing was used for 328 case-parental triads enrolled in the National Birth Defects Prevention Study (NBDPS). To evaluate the interaction of two genes, we applied a conditional logistic regression model for all possible SNP pairs within two respective genes by contrasting the affected infants with their pseudo-controls. The findings were replicated in an independent sample …

Targeting Cd47 As A Novel Immunotherapy For Multiple Myeloma, Jennifer Sun, Barbara Muz, Kinan Alhallak, Matea Markovic, Shannon Gurley, Zhe Wang, Nicole Guenthner, Katherine Wasden, Mark Fiala, Justin King, Daniel Kohnen, Noha Nabil Salama, Ravi Vij, Abdel Kareem Azab

Open Access Publications

Multiple myeloma (MM) remains to be incurable despite recent therapeutic advances. CD47, an immune checkpoint known as the "don't eat me" signal, is highly expressed on the surface of various cancers, allowing cancer cells to send inhibitory signals to macrophages and impede phagocytosis and immune response. In this study, we hypothesized that blocking the "don't eat me" signaling using an anti-CD47 monoclonal antibody will induce killing of MM cells. We report that CD47 expression was directly correlated with stage of the disease, from normal to MGUS to MM. Moreover, MM cells had remarkably higher CD47 expression than other cell populations …

Mechanical Stimuli Affect Escherichia Coli Heat-Stable Enterotoxin-Cyclic Gmp Signaling In A Human Enteroid Intestine-Chip Model, Laxmi Sunuwar, Jianyi Yin, Magdalena Kasendra, Katia Karalis, James Kaper, James Fleckenstein, Mark Donowitz

Open Access Publications

No abstract provided.

Real-Time Colorectal Cancer Diagnosis Using Pr-Oct With Deep Learning, Yifeng Zeng, Shiqi Xu, William C. Chapman Jr., Shuying Li, Zahra Alipour, Heba Abdelal, Deyali Chatterjee, Matthew Mutch, Quing Zhu

Open Access Publications

No abstract provided.

Carpal Tunnel Syndrome Among Male French Farmers And Agricultural Workers: Is It Only Associated With Physical Exposure?, Yves Roquelaure, Sylvaine Jégo, Béatrice Geoffroy-Perez, Emilie Chazelle, Alexis Descatha, Bradley Evanoff, Ronan Garlantézec, Julie Bodin

Open Access Publications

No abstract provided.

Mycn Amplification And Atrx Mutations Are Incompatible In Neuroblastoma, Maged Zeineldin, Xiang Chen, Michael A. Dyer

Open Access Publications

No abstract provided.

Activity-Dependent Isomerization Of Kv4.2 By Pin1 Regulates Cognitive Flexibility, Jia-Hua Hu, Cole Malloy, G. Travis Tabor, Jakob J. Gutzmann, Ying Liu, Daniel Abebe, Rose-Marie Karlsson, Stewart Durell, Heather A. Cameron, Dax A. Hoffman

Open Access Publications

No abstract provided.

Reporting Guidelines, Review Of Methodological Standards, And Challenges Toward Harmonization In Bone Marrow Adiposity Research. Report Of The Methodologies Working Group Of The International Bone Marrow Adiposity Society, Josefine Tratwal, Erica L Scheller, Et Al

Open Access Publications

The interest in bone marrow adiposity (BMA) has increased over the last decade due to its association with, and potential role, in a range of diseases (osteoporosis, diabetes, anorexia, cancer) as well as treatments (corticosteroid, radiation, chemotherapy, thiazolidinediones). However, to advance the field of BMA research, standardization of methods is desirable to increase comparability of study outcomes and foster collaboration. Therefore, at the 2017 annual BMA meeting, the International Bone Marrow Adiposity Society (BMAS) founded a working group to evaluate methodologies in BMA research. All BMAS members could volunteer to participate. The working group members, who are all active preclinical …

Phase 1–2 Trial Of Antisense Oligonucleotide Tofersen For Sod1 Als, Timothy Miller, Robert C. Bucelli, Alan Pestronk, Et Al.

Open Access Publications

No abstract provided.

Combined Abdominal Heterotopic Heart And Aorta Transplant Model In Mice, Hao Dun, Li Ye, Yuehui Zhu, Brian W Wong

Open Access Publications

BACKGROUND: Allograft vasculopathy (AV) remains a major obstacle to long-term allograft survival. While the mouse aortic transplantation model has been proven as a useful tool for study of the pathogenesis of AV, simultaneous transplantation of the aorta alongside the transplantation of another organ may reveal more clinically relevant mechanisms that contribute to the pathogenesis of chronic allograft rejection. Therefore, we developed a combined abdominal heart and aorta transplantation model in mice which benefits from reducing animal and drug utilization, while providing an improved model to study the progressive nature of AV.

METHODS: The middle of the infrarenal aorta of the …

The Chromatin Remodeling Enzyme Chd4 Regulates Genome Architecture In The Mouse Brain, Jared V. Goodman, Tomoko Yamada, Yue Yang, Lingchun Kong, Dennis Y. Wu, Guoyan Zhao, Harrison W. Gabel, Azad Bonni

Open Access Publications

No abstract provided.

12-Lox Catalyzes The Oxidation Of 2-Arachidonoyl-Lysolipids In Platelets Generating Eicosanoid-Lysolipids That Are Attenuated By Ipla2Γ Knockout, Xinping Liu, Harold F. Sims, Christopher M. Jenkins, Shaoping Guan, Beverly G. Dilthey, Richard W. Gross

Open Access Publications

No abstract provided.