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2019

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Simulation Research On Pedestrian Evacuation Path Selection In The Metro Station, Sun Di, Zhou Jin, Xueying Gao, Ting Jiao, Lixian Zhao Dec 2019

Simulation Research On Pedestrian Evacuation Path Selection In The Metro Station, Sun Di, Zhou Jin, Xueying Gao, Ting Jiao, Lixian Zhao

Journal of System Simulation

Abstract: As the underground environment is multilayered, more confined space underground, there are many services and facilities, so that when people evacuate the subway, they will have a variety of features and choices. Path probability selection of underground pedestrian evacuation is discussed. In the first stage, models are used to plan several routes. In the second stage, according to the data of real time passenger flow of the railway station, the density of passenger flow is taken as a variable to obtain the time of pedestrian evacuation through different facilities. The traffic capacity of every passage and facility …


Design And Analysis Of Sustained-G Flight Simulator Control Algorithm, Xiaoguang Zhou, Yihong Fang, Huaiying Tian, Mingzhi Yao Dec 2019

Design And Analysis Of Sustained-G Flight Simulator Control Algorithm, Xiaoguang Zhou, Yihong Fang, Huaiying Tian, Mingzhi Yao

Journal of System Simulation

Abstract: In order to solve the problem of mismatch exist between angular motions by Sustained-G Flight Simulator pilot through his proprioceptive receptors and visual receptors, the control algorithm of Sustained-G Flight Simulator is designed. The formulas relative to control input is derived; the mathematical model of human proprioceptive system is researched, the relationship between pilot's perceptual angular and rotating linear acceleration vectors and angular accelerations is given, based on that, the control algorithm of Sustained-G Flight Simulator is proposed, which can make a match existence between the angular motion perceived by Sustained-G Flight Simulator pilot and aircraft pilot. The simulation …


Operation Control Method For Connected And Autonomous Vehicles At Intersection, Linguo Chai, Baigen Cai, Shangguan Wei, Wang Jian, Junjie Chen Dec 2019

Operation Control Method For Connected And Autonomous Vehicles At Intersection, Linguo Chai, Baigen Cai, Shangguan Wei, Wang Jian, Junjie Chen

Journal of System Simulation

Abstract: A novel approach for coordinating connected and autonomous vehicles at intersection is proposed in this paper. The road connecting the specific intersection is divided into two areas: status calculation area and status adjustment area. When the vehicle enters the status calculation area, LOOSE algorithm which is implemented in the infrastructure would be triggered to calculate the target status of the vehicle for it to avoid collision in the intersection. The results of LOOSE would be optimized by COMPACT algorithm with the objective of minimum queue length. And then operational suggestions for the vehicle to …


Research On Multi-Objective Adaptive Equalization Control Strategy Based On Soh, Xiangwei Guo, Sumin Han, Hua Xian, Donglei Xie Dec 2019

Research On Multi-Objective Adaptive Equalization Control Strategy Based On Soh, Xiangwei Guo, Sumin Han, Hua Xian, Donglei Xie

Journal of System Simulation

Abstract: By analyzing the root-cause of inconsistency in the battery pack, and the coupling relationship between the internal and external factors of the battery, the multi-objective adaptive equalization control strategy based on SOH (State of Health) is proposed, the equalization of SOH, temperature and SOC can be realized simultaneously. SOH equalization achieves the same degree of lifetime attenuation of each cell in different working conditions, the inconsistency can be improved substantially. SOC equalization and temperature equalization further avoid the expansion of the inconsistency of single battery. The simulation model of balancing circuit is built in Matlab/Simulink for four series cells. …


Recurrent Cmacnn Control For Space Robot With Fully Flexible Arms And Elastic Base, Xiaoqin Huang, Chen Li Dec 2019

Recurrent Cmacnn Control For Space Robot With Fully Flexible Arms And Elastic Base, Xiaoqin Huang, Chen Li

Journal of System Simulation

Abstract: The trajectory tracking of elastic base and double flexible arms for a free-floating space robot system with fully flexible arms and elastic base is discussed. The elastic connection between the base and the arm is considered as a linear spring and dynamics model of the system which is regarded as a two- time scale system is derived. For the slow-varying subsystem, the recursive CMAC neural network (CMACNN) which has good dynamic characteristics is used to approximate uncertainties of dynamical equation and a recursive CMAC neural network control scheme which improves the tracking performance is designed to improve the …


Design Of Multi -Port Converter For Dc Micro-Grid System With Wind-Photovoltaic Storage, Liu Hui, Tinglong Pan Dec 2019

Design Of Multi -Port Converter For Dc Micro-Grid System With Wind-Photovoltaic Storage, Liu Hui, Tinglong Pan

Journal of System Simulation

Abstract: In order to coordinate energy, load and storage in DC micro-grid system and make efficient utilization of new energy, a multi-port converter for DC micro-grid hybrid energy storage is proposed. According to the composition rule of multi-port converter, by inserting the Buck-boost converter and bidirectional Buck-boost converter into the bootstrap converter of Luo-converter, the DC converter topology which can be used for complementation of wind-photovoltaic storage is produced. Two-way transmission of energy is realized. The analysis of all kinds of working conditions shows that each port of the converter is able to work independently and cooperatively. Different …


Research On Gear Transmission Error Based On Chaotic Ant Swarm Optimization, Xinrong Liu, Zhonghou Wang, Kubo Aizoh Dec 2019

Research On Gear Transmission Error Based On Chaotic Ant Swarm Optimization, Xinrong Liu, Zhonghou Wang, Kubo Aizoh

Journal of System Simulation

Abstract: In this paper, the dynamic model of bending- torsion -axis- heat of cylindrical helical gear system is established by considering the time-varying meshing stiffness and meshing impulse excitation. The NURBS method is used to reconstruct the trimming surface through superimposing the theoretical tooth surface and trimming tooth surface, then the influence of different trimming on the gear transmission error is analyzed. The optimal trimming surface is obtained by Chaos Ant Colony Algorithm. The finite element method is used to analyze the transmission error of the modified gear and the unshaped gear. The numerical simulation analysis shows that the amplitude …


The Method Summary Of Generating Large-Scale Artificial Population In An Artificial Society, Yuanzheng Ge, Zhichao Song, Rongqing Meng Dec 2019

The Method Summary Of Generating Large-Scale Artificial Population In An Artificial Society, Yuanzheng Ge, Zhichao Song, Rongqing Meng

Journal of System Simulation

Abstract: The generation of large-scale artificial population is the fundamental data of high-resolution agent-based artificial society. By the comparison of typical artificial population models, the basic elements, generating methods, and evolving rules, the development of artificial society, generation of population database, the establishment of spatial-temporal relationship, evolving rules of behavior, and reconstruction of social relationship are analyzed. Furthermore, data-driven method and open interface framework of artificial population are discussed, and the future direction and development are listed.


High-Order Reconstruction Of Maneuvering Decision-Making Process In Close Air Combat, Ya’Nan Kou, Longting Jiang, Wang Dong Dec 2019

High-Order Reconstruction Of Maneuvering Decision-Making Process In Close Air Combat, Ya’Nan Kou, Longting Jiang, Wang Dong

Journal of System Simulation

Abstract: Aiming at the reconfiguration of maneuvering decision-making in air combat, an extraction model of key maneuvering decision-making points is constructed. Based on the actual aircraft flight status data, by introducing the concept of jerkiness degree in physics, four indexes of pitching Angle, yaw Angle, roll Angle and speed jerkiness, are selected to construct evaluation index system of key maneuvering decision point. By using the theory of information entropy , the relevant indexes are reduced and the comprehensive evaluation value are obtained. Then maneuvering area is divided according to time domain, the decision points are extracted, and maneuvering decision-making refactoring …


Simulation Of Axial Vibration Characteristics Of Marine Riser Under Suspension Mode, Chuan Wang, Li Jun, Zhenqiang Xie, Guorong Wang Dec 2019

Simulation Of Axial Vibration Characteristics Of Marine Riser Under Suspension Mode, Chuan Wang, Li Jun, Zhenqiang Xie, Guorong Wang

Journal of System Simulation

Abstract: The mechanical simulation model of vertical vibration of Marine riser under suspension mode has been established based on the basic principle of dynamics theory. In the model, the influence of heave movement and top tensioner is considered. The vibration equation is solved by the finite difference method to obtain the distribution of axial stress and displacement. Besides, the effects of suspension mode, buoyancy block,water depth, wall thickness and LMRP on the vertical vibration of riser are discussed. According to the results, the soft suspension mode is superior to the hard suspension mode. The buoyancy blocks will increase the …


Simulation Of The Resistance Of Superhydrophobic Microchannel In Turbulent Regime, Chunxi Li, Qingze Cui, Xuemin Ye Dec 2019

Simulation Of The Resistance Of Superhydrophobic Microchannel In Turbulent Regime, Chunxi Li, Qingze Cui, Xuemin Ye

Journal of System Simulation

Abstract: VOF model and the Realizable k-ε turbulent model are used to simulate the three-dimensional flow field of superhydrophobic microchannels with longitudinal and transverse microstructures in turbulent regime, the effects of structural parameters on the resistance characteristics of superhydrophobic surface are analyzed. The results show that the superhydrophobic microchannels with longitudinal microgrooves exhibit significant reductions in drag; with the increase of the free shear area ratio and the width of the microchannel, the ratio of pressure drop increases, and the average friction factor decreases, as well as the drag reduction effect is highly significant; with the increase of …


Where Was I Going? What Was The Point? Archetypes, Frame, And Social Transgressions In Ovid And Twain, Jessica Bates Dec 2019

Where Was I Going? What Was The Point? Archetypes, Frame, And Social Transgressions In Ovid And Twain, Jessica Bates

Honors Theses

The sound of a narrator telling a story can be difficult to depict in written prose, and yet both Ovid and Twain capture the effect of an old man telling a story; Ovid through Nestor's Story in The Metamorphoses and Twain in "The Celebrated Jumping Frog of Calaveras County." They both use this framework to discuss the theme of social transgressions. I maintain that both Twain and Ovid use a variation on the wise-mentor archetype as a frame to discuss, through the use of satire, social transgressions which neither of their narrators condemn. I aim to explore Ovid and Twain's …


Dosimetric Feasibility Of Utilizing The Viewray Magnetic Resonance Guided Linac System For Image-Guided Spine Stereotactic Body Radiation Therapy, Gage Redler, Tynan Stevens, Jochen Cammin, Martha Malin, Olga Green, Sasa Mutic, Sean Pitroda, Bulent Aydogan Dec 2019

Dosimetric Feasibility Of Utilizing The Viewray Magnetic Resonance Guided Linac System For Image-Guided Spine Stereotactic Body Radiation Therapy, Gage Redler, Tynan Stevens, Jochen Cammin, Martha Malin, Olga Green, Sasa Mutic, Sean Pitroda, Bulent Aydogan

Open Access Publications

INTRODUCTION: Spine stereotactic body radiation therapy (SBRT) achieves favorable outcomes compared to conventional radiotherapy doses/fractionation. The spinal cord is the principal dose-limiting organ-at-risk (OAR), and safe treatment requires precise immobilization/localization. Therefore, image guidance is paramount to successful spine SBRT. Conventional X-ray imaging and alignment to surrogate bony anatomy may be inadequate, whereas magnetic resonance imaging (MRI) directly visualizes the dose-limiting cord. This work assessed the dosimetric capability of the ViewRay (ViewRay Inc. Oakwood Village, OH) magnetic resonance (MR) guided linac (MR-Linac) for spine SBRT.

METHODS: Eight spine SBRT patients without orthopedic hardware who were previously treated on a TrueBeam using …


Distinct Roles Of Interferon Alpha And Beta In Controlling Chikungunya Virus Replication And Modulating Neutrophil-Mediated Inflammation, Lindsey E Cook, Marissa C Locke, Alissa R Young, Kristen Monte, Matthew L Hedberg, Raeann M Shimak, Kathleen C F Sheehan, Deborah J Veis, Michael S Diamond, Deborah J Lenschow Dec 2019

Distinct Roles Of Interferon Alpha And Beta In Controlling Chikungunya Virus Replication And Modulating Neutrophil-Mediated Inflammation, Lindsey E Cook, Marissa C Locke, Alissa R Young, Kristen Monte, Matthew L Hedberg, Raeann M Shimak, Kathleen C F Sheehan, Deborah J Veis, Michael S Diamond, Deborah J Lenschow

Open Access Publications

Type I interferons (IFNs) are key mediators of the innate immune response. Although members of this family of cytokines signal through a single shared receptor, biochemical and functional variation exists in response to different IFN subtypes. While previous work has demonstrated that type I IFNs are essential to control infection by chikungunya virus (CHIKV), a globally emerging alphavirus, the contributions of individual IFN subtypes remain undefined. To address this question, we evaluated CHIKV pathogenesis in mice lacking IFN-β (IFN-β knockout [IFN-β-KO] mice or mice treated with an IFN-β-blocking antibody) or IFN-α (IFN regulatory factor 7 knockout [IRF7-KO] mice or mice …


Bayesian Characterization Of Main-Sequence Binaries In The Old Open Cluster Ngc 188, Roger E. Cohen, Ted Von Hippel, Aaron M. Geller Dec 2019

Bayesian Characterization Of Main-Sequence Binaries In The Old Open Cluster Ngc 188, Roger E. Cohen, Ted Von Hippel, Aaron M. Geller

Publications

The binary fractions of open and globular clusters yield powerful constraints on their dynamical state and evolutionary history. We apply publicly available Bayesian analysis tools to a UBV RIJHKS photometric catalog of the open cluster NGC 188 to detect and characterize photometric binaries along the cluster main sequence. This technique has the advantage of self-consistently handling photometric errors, missing data in various bandpasses, and star-by-star prior constraints on cluster membership. Simulations are used to verify uncertainties and quantify selection biases in our analysis, illustrating that among binaries with mass ratios >0.5, we recover the binary fraction to better than …


Localized Dielectric Loss Heating In Dielectrophoresis Devices, Tae Joon Kwak, Imtiaz Hossen, Rashid Bashir, Woo-Jin Chang, Chung-Hoon Lee Dec 2019

Localized Dielectric Loss Heating In Dielectrophoresis Devices, Tae Joon Kwak, Imtiaz Hossen, Rashid Bashir, Woo-Jin Chang, Chung-Hoon Lee

Electrical and Computer Engineering Faculty Research and Publications

Temperature increases during dielectrophoresis (DEP) can affect the response of biological entities, and ignoring the effect can result in misleading analysis. The heating mechanism of a DEP device is typically considered to be the result of Joule heating and is overlooked without an appropriate analysis. Our experiment and analysis indicate that the heating mechanism is due to the dielectric loss (Debye relaxation). A temperature increase between interdigitated electrodes (IDEs) has been measured with an integrated micro temperature sensor between IDEs to be as high as 70 °C at 1.5 MHz with a 30 Vpp applied voltage to our ultra-low …


Chemical Constituent And Antimalarial Activity Based On Inhibition Of Heme Polymerization From Water Extract Of Yellow Root (Arcangelisia Flava L. Merr), Yatri Hapsari, Partomuan Simanjuntak, Wien Kusharyoto, Sumi Hudiyono Dec 2019

Chemical Constituent And Antimalarial Activity Based On Inhibition Of Heme Polymerization From Water Extract Of Yellow Root (Arcangelisia Flava L. Merr), Yatri Hapsari, Partomuan Simanjuntak, Wien Kusharyoto, Sumi Hudiyono

Chimica et Natura Acta

In developing countries, malaria remains a disease that can spread easily and caused death. Malaria is an infectious disease caused by Plasmodium sp involving female anopheles masquitos during its transmission. Arcangelisia flava L. Merr has been investigated earlier that it can inhibited P. falciparum growth. Method of antimalarial activity based on inhibition of heme polymerization can confirm one of the mechanism of antimalarial drugs. The aim of this research to study further antimalarial activity and IC50 based on inhibition of heme polymerization and determine the chemical constituent from water extract of A. flava L. Merr. This research was conducted through …


Kajian Substitusi Kacang Komak (Lablab Purpureus (L.) Sweet) Terhadap Nasi Kecambah Sorgum Merah, Endah Wulandari, Heni Radiani Arifin, Een Sukarminah, Elazmanawati Lembong, Devi Nurul Fadilah Dec 2019

Kajian Substitusi Kacang Komak (Lablab Purpureus (L.) Sweet) Terhadap Nasi Kecambah Sorgum Merah, Endah Wulandari, Heni Radiani Arifin, Een Sukarminah, Elazmanawati Lembong, Devi Nurul Fadilah

Chimica et Natura Acta

Nasi sorgum memiliki nutrisi yang setara dengan nasi beras padi. Namun permasalahan yang terdapat dalam sorgum yaitu mengandung zat antinutrisi seperti tanin yang cukup tinggi dan memiliki kualitas protein rendah karena kurangnya kandungan lisin. Tujuan dari penelitian ini adalah untuk menentukan hubungan keeratan substitusi kacang komak terhadap daya cerna protein nasi sorgum merah. Metode penelitian yang digunakan yaitu analisis deskriptif (regresi korelasi). Percobaan terdiri dari 6 perlakuan yaitu dengan penambahan kacang komak sampai dengan 50% pada beras sorgum dan beras kecambah sorgum. Hasil penelitian ini menunjukkan nasi kecambah sorgum merah dengan penambahan kacang komak akan meningkatkan kadar tanin sebesar 0,189%. …


Peranan Ion Logam Kobalt Terhadap Kinerja Fermentasi Dan Toleransi Cekaman Lingkungan Sel Ragi Saccharomyces Cerevisiae, Saadah D. Rachman, Nadia Maulida, Agus Safari, Nenden I. Anggraeni, Muhammad Fadhlillah, Safri Ishmayana Dec 2019

Peranan Ion Logam Kobalt Terhadap Kinerja Fermentasi Dan Toleransi Cekaman Lingkungan Sel Ragi Saccharomyces Cerevisiae, Saadah D. Rachman, Nadia Maulida, Agus Safari, Nenden I. Anggraeni, Muhammad Fadhlillah, Safri Ishmayana

Chimica et Natura Acta

Semakin menipisnya ketersediaan bahan bakar fosil mendorong dikembangkannya energi alternatif, salah satunya adalah bioetanol. Selama proses fermentasi bioetanol, ragi Saccharomyces cerevisiae dapat terpapar berbagai cekaman lingkungan yang dapat memberikan dampak negatif bagi sel ragi. Salah satu upaya untuk meningkatkan toleransi sel ragi adalah dengan menambahkan ion logam kedalam media fermentasi. Penelitian ini bertujuan untuk mengetahui pengaruh suplementasi ion kobalt terhadap kinerja fermentasi, toleransi sel ragi terhadap cekaman lingkungan, dan terhadap morfologi sel ragi. Metode penelitian meliputi proses fermentasi yang dilaksanakan selama 120 jam dalam media yeast nitrogen base dengan 10% b/v glukosa sebagai sumber karbon dan variasi penambahan konsentrasi ion …


Identifikasi Dan Karakterisasi Profil Asam Lemak Virgin Coconut Oil Dengan Penambahan Ekstrak Etanol Kunyit Putih (Curcuma Zedoaria Rosc.), Ni Pt. Pande Mirah Surya Dewi, Ni Wayan Bogoriani, Ni Made Suaniti Dec 2019

Identifikasi Dan Karakterisasi Profil Asam Lemak Virgin Coconut Oil Dengan Penambahan Ekstrak Etanol Kunyit Putih (Curcuma Zedoaria Rosc.), Ni Pt. Pande Mirah Surya Dewi, Ni Wayan Bogoriani, Ni Made Suaniti

Chimica et Natura Acta

Hasil perkebunan kelapa di Provinsi Bali cukup banyak namun pemasarannya dalam bentuk produk diversifikasi masih belum maksimal, contohnya virgin coconut oil (VCO). Virgin coconut oil mempunyai harga jual tinggi serta berbagai manfaat di bidang kesehatan maupun kosmetik. Tujuan penelitian ini adalah mengetahui kadar bilangan peroksida, asam lemak bebas, serta kapasitas antioksidan VCO dengan penambahan ekstrak etanol kunyit putih serta mengetahui profil asam lemak bebas VCO dengan penambahan ekstrak etanol kunyit putih. Metode penelitian ini adalah rancangan the pretest – posttest control group design dengan perlakuan 3 konsentrasi ekstrak etanol kunyit putih yaitu 5%, 10% dan 15% serta diukur pada awal, …


Fotokatalisis Komposit Silika Sekam Padi Modifikasi Seng Oksida Untuk Menurunkan Konsentrasi Kromium(Vi), Diana Rakhmawaty Eddy, L. Ahmad Na’Ani, Rustaman Rustaman, Solihudin Solihudin Dec 2019

Fotokatalisis Komposit Silika Sekam Padi Modifikasi Seng Oksida Untuk Menurunkan Konsentrasi Kromium(Vi), Diana Rakhmawaty Eddy, L. Ahmad Na’Ani, Rustaman Rustaman, Solihudin Solihudin

Chimica et Natura Acta

Penelitian ini bertujuan untuk mengetahui pengaruh penambahan silika sekam padi untuk meningkatkan efektifitas degradasi limbah oleh fotokatalis ZnO/SiO2. Hasil sebelumnya ZnO/SiO2 komposisi 95/5 (w/w) telah menurunkan konsentrasi kromium yang ada dalam buangan limbah hasil praktikum sebesar 82,6%. Tahapan penelitiannya dengan preparasi arang sekam padi dengan menggunakan tabung pirolisis kemudian diekstraksi untuk menghasilkan silika, pembuatan komposit ZnO/SiO2 dengan komposisi 95/5; 90/10; dan 85/15 serta uji aktivitas dalam menurunkan konsentrasi kromium(VI). Hasil SEM-EDS menunjukkan sudah terbentuknya komposit SiO2 pada ZnO. Penurunan konsentrasi kromium(VI) sebesar 83,3% pada komposisi silicon dioksida 90/10 (w/w).


Penentuan Besi (Iii) Secara Voltammetri Menggunakan Elektrode Grafit Pensil, Rizki Muharami Cedia Sari, Elin Marlin, Yeni Wahyuni Hartati Dec 2019

Penentuan Besi (Iii) Secara Voltammetri Menggunakan Elektrode Grafit Pensil, Rizki Muharami Cedia Sari, Elin Marlin, Yeni Wahyuni Hartati

Chimica et Natura Acta

Besi (Fe) adalah unsur yang penting dalam organisme hidup karena aktivitas biologisnya, misalnya sebagai kompleks porfirin dalam hemoglobin, mioglobin dan sitokrom. Namun, Fe yang melebihi ambang batas dalam air minum, sebagai Fe(II) dan Fe(III), dapat berdampak buruk bagi kesehatan sehingga penentuan kadar Fe menjadi penting. Penentuan Feumumnya dilakukan secara spektroanalisis maupun elektroanalisis. Dalam penelitian ini, penentuan Fe(III) secara voltammetri pulsa diferensial telah dilakukan menggunakan elektrode grafit pensil. Hasil penelitian menunjukkan kondisi optimum pengukuran meliputi: media buffer asetat pH 5,0;  potensial awal -0,5 V; tahap potensial 4,0  mV;  dan modulasi amplitudo 25,0 mV dengan waktu modulasi 0,05 s. Pengukuran Fe(III)  dalam …


Analisa Karakteristik Simplisia Buah Andaliman (Zanthoxyllum Acanthopodium) Serta Aktivitas Penghambatan Xantin Oksidase, Dhini Anisa, Fajar Fauzi Abdullah, Riza Apriani, Gun Gun Gumilar, Iqbal Musthapa Dec 2019

Analisa Karakteristik Simplisia Buah Andaliman (Zanthoxyllum Acanthopodium) Serta Aktivitas Penghambatan Xantin Oksidase, Dhini Anisa, Fajar Fauzi Abdullah, Riza Apriani, Gun Gun Gumilar, Iqbal Musthapa

Chimica et Natura Acta

Gout atau hiperurisemia adalah keadaan dimana terjadinya peningkatan kadar asam urat dalam darah. Xantin oksidase berperan dalam oksidasi xantin dan hipoxantin menjadi asam urat. Salah satu pengobatan kelebihan asam urat adalah menghambat aktivitas enzim xantin oksidase. Penelitian ini menguji aktivitas anti asam urat ekstrak etanol dari buah andaliman kemudian dan menentukan nilai persentase penghambatannya. Hasil pengujian menunjukkan bahwa ekstrak buah andaliman memiliki potensi yang baik untuk menjadi kandidat antihiperurisemia, dengan nilai persentase penghambatannya sebesar 70,67% pada konsentrasi ekstrak sebesar 100 µg/mL.


Pola Perubahan Urutan Asam Amino Pada Hemaglutinin Virus H5n1 Indonesia, Idar Idar, Soni Muhsinin, Umi Baroroh, Muhammad Yusuf Dec 2019

Pola Perubahan Urutan Asam Amino Pada Hemaglutinin Virus H5n1 Indonesia, Idar Idar, Soni Muhsinin, Umi Baroroh, Muhammad Yusuf

Chimica et Natura Acta

Wabah virus flu burung tipe A, H5N1 yang memiliki patogenisitas tinggi diketahui telah menginfeksi dan mematikan jutaan unggas di Indonesia sehingga menimbulkan kerugian yang besar secara ekonomi pada peternakan unggas.  Hemaglutinin pada virus ini merupakan salah satu faktor penentu patogenisitas virus. Selain itu, komponen virus ini rentan mengalami mutasi dan dapat menyebabkan pergeseran dan penataan ulang antigen virus sehingga tercipta clade virus yang baru. Kemudian peranan HA dalam penempelan virus ke sel inang menyebabkan HA ini menjadi target untuk pengembangan obat maupun vaksin. Dengan demikian, penelitian ini bertujuan mencari pola urutan asam amino hemaglutinin yang khas pada H5N1 yang memiliki …


Newsroom, Georgia Southern University Dec 2019

Newsroom, Georgia Southern University

Newsroom (2006-2023)

  • Georgia Southern first-generation student graduates magna cum laude
  • Georgia Southern graduate rediscovers passion for art in Betty Foy Sanders Department of Art
  • Georgia Southern student overcomes hurdles to complete her degree after 21 years
  • Georgia Southern graduate has 60 family members, friends coming to watch 'biggest accomplishment'


Fapaac Minutes 12/12/2019, Faculty And P&A Affairs Committee Dec 2019

Fapaac Minutes 12/12/2019, Faculty And P&A Affairs Committee

Faculty and P&A Affairs Committee

No abstract provided.


Working Paper No. 39, Neoliberalism As A Variant Of Capitalism, Justin Pilarski Dec 2019

Working Paper No. 39, Neoliberalism As A Variant Of Capitalism, Justin Pilarski

Working Papers in Economics

Economic systems evolve over time in adapting to the needs and deficiency of the system. This inquiry seeks to establish Neoliberalism as—in the language of Barry Clark—a variant of capitalism that evolved out of retaliation of the regulated variant of capitalism. We utilize Barry Clark’s work on the evolution of economic systems in establishing the pattern of adaptation in American capitalism. Then we establish and analyze the neoliberal variant of capitalism in how this evolution retaliated against the existing system rather than adapting the preceding variant. We then consider how the economics profession reacted when the neoliberal economic policies failed …


Book Review Of Religion, History, And Place In The Origin Of Settled Life, Edited By Ian Hodder, Jane Peterson Dec 2019

Book Review Of Religion, History, And Place In The Origin Of Settled Life, Edited By Ian Hodder, Jane Peterson

Social and Cultural Sciences Faculty Research and Publications

No abstract provided.


Kenyon Collegian - December 12, 2019 Dec 2019

Kenyon Collegian - December 12, 2019

The Kenyon Collegian

No abstract provided.


Gantenerumab Reduces Amyloid-Β Plaques In Patients With Prodromal To Moderate Alzheimer's Disease: A Pet Substudy Interim Analysis, Gregory Klein, Paul Delmar, Nicola Voyle, Sunita Rehal, Carsten Hofmann, Danielle Abi-Saab, Mirjana Andjelkovic, Smiljana Ristic, Guoqiao Wang, Randall Bateman, Geoffrey A Kerchner, Monika Baudler, Paulo Fontoura, Rachelle Doody Dec 2019

Gantenerumab Reduces Amyloid-Β Plaques In Patients With Prodromal To Moderate Alzheimer's Disease: A Pet Substudy Interim Analysis, Gregory Klein, Paul Delmar, Nicola Voyle, Sunita Rehal, Carsten Hofmann, Danielle Abi-Saab, Mirjana Andjelkovic, Smiljana Ristic, Guoqiao Wang, Randall Bateman, Geoffrey A Kerchner, Monika Baudler, Paulo Fontoura, Rachelle Doody

Open Access Publications

BACKGROUND: We previously investigated low doses (105 or 225 mg) of gantenerumab, a fully human monoclonal antibody that binds and removes aggregated amyloid-β by Fc receptor-mediated phagocytosis, in the SCarlet RoAD (SR) and Marguerite RoAD (MR) phase 3 trials. Several lines of evidence suggested that higher doses may be necessary to achieve clinical efficacy. We therefore designed a positron emission tomography (PET) substudy to evaluate the effect of gantenerumab uptitrated to 1200 mg every 4 weeks on amyloid-β plaques as measured using florbetapir PET in patients with prodromal to moderate Alzheimer's disease (AD).

METHODS: A subset of patients enrolled in …