Digital Commons Network^™

Risks Of Harm With Cannabinoids, Cannabis, And Cannabis-Based Medicine For Pain Management Relevant To Patients Receiving Pain Treatment: Protocol For An Overview Of Systematic Reviews, Ian Gilron, Fiona M. Blyth, Louisa Degenhardt, Marta Di Forti, Christopher Eccleston, Simon Haroutounian, Andrew Moore, Andrew S.C. Rice, Mark Wallace

Open Access Publications

No abstract provided.

Cannabinoids, Cannabis, And Cannabis-Based Medicine For Pain Management: A Protocol For An Overview Of Systematic Reviews And A Systematic Review Of Randomised Controlled Trials, Emma Fisher, Christopher Eccleston, Louisa Degenhardt, David P. Finn, Nanna B. Finnerup, Ian Gilron, Simon Haroutounian, Elliot Krane, Andrew S.C. Rice, Michael Rowbotham, Mark Wallace, R. Andrew Moore

Open Access Publications

No abstract provided.

High-Density Functional Diffuse Optical Tomography Based On Frequency-Domain Measurements Improves Image Quality And Spatial Resolution, Matthaios Doulgerakis, Adam T. Eggebrecht, Hamid Dehghani

Open Access Publications

No abstract provided.

A Protocol For The Systematic Review And Meta-Analysis Of Studies In Which Cannabinoids Were Tested For Antinociceptive Effects In Animal Models Of Pathological Or Injury-Related Persistent Pain, Nadia Soliman, Andrea G. Hohmann, Simon Haroutounian, Kimberley Wever, Andrew S.C. Rice, David P. Finn

Open Access Publications

No abstract provided.

Irsp53 Coordinates Ampk And 14-3-3 Signaling To Regulate Filopodia Dynamics And Directed Cell Migration, David J. Kast, Roberto Dominquez

Open Access Publications

No abstract provided.

Association Between Mortality And Implantable Cardioverter-Defibrillators By Aetiology Of Heart Failure: A Propensity-Matched Analysis Of The Warcef Trial, Tetz C. Lee, Douglas L. Mann, Et Al

Open Access Publications

No abstract provided.

A Promising Bioconjugate Vaccine Against Hypervirulent Klebsiella Pneumoniae, Mario F. Feldman, Anne E. Mayer Bridwell, Nichollas E. Scott, Evgeny Vinogradov, Samuel R. Mckee, Sthefany M. Chavez, Joy Twentyman, Christina L. Stallings, David A. Rosen, Christian M. Harding

Open Access Publications

No abstract provided.

A Rubisco-Binding Protein Is Required For Normal Pyrenoid Number And Starch Sheath Morphology In Chlamydomonas Reinhardtii, Alan K. Itakura, Kher Xing Chan, Nicky Atkinson, Leif Pallesen, Lianyong Wang, Gregory Reeves, Weronika Patena, Oliver Caspari, Robyn Roth, Ursula Goodenough, Alistair J. Mccormick, Howard Griffiths, Martin C. Jonikas

Open Access Publications

No abstract provided.

Primary Adenoid Cystic Carcinoma Of The Liver: Case Report And Review Of The Literature, Jianbo Zhang, Yuanyuan Wang, Dengfeng Cao

Open Access Publications

Adenoid cystic carcinoma (ACC) is an uncommon tumor primarily occurring in the salivary glands and is relatively rare in other sites. In the liver, only one primary adenoid cystic carcinoma has been reported in the English literature. Here we presented a primary hepatic adenoid cystic carcinoma in a 44 years old male. We described its histopathologic features and its immunohistochemical profile, and reviewed the literature. The surgical treatment and patient follow up information was also presented.

Combined Anti-Inflammatory And Neuroprotective Treatments Have The Potential To Impact Disease Phenotypes In Cln3−/− Mice, Marta A. Tarczyluk-Wells, Christoph Salzlechner, Allison R. Najafi, Ming J. Lim, David Smith, Frances M. Platt, Brenda P. Williams, Jonathan D. Cooper

Open Access Publications

No abstract provided.

Riding The Rhythm Of Melatonin Through Pregnancy To Deliver On Time, Ronald Mccarthy, Emily S. Jungheim, Justin C. Fay, Keenan Bates, Erik D. Herzog, Sarah K. England

Open Access Publications

No abstract provided.

The Nuclear Receptor Rev-Erbα Modulates Th17 Cell-Mediated Autoimmune Disease, Christina Chang, Chin-San Loo, Xuan Zhao, Laura A. Solt, Yuqiong Liang, Sagar P. Bapat, Han Cho, Theodore M. Kamenecka, Mathias Leblanc, Annette R. Atkins, Ruth T. Yu, Michael Downes, Thomas P. Burris, Ronald M. Evans, Ye Zheng

Open Access Publications

No abstract provided.

Biomarkers And Preclinical Models For Adult T-Cell Leukemia-Lymphoma Treatment, Lee Ratner

Open Access Publications

No abstract provided.

Genetic Vulnerability To Experiencing Child Maltreatment, Patrizia Pezzoli, Jan Antfolk, Alexander S. Hatoum, Pekka Santtila

Open Access Publications

No abstract provided.

Genetic Architecture Of Human Plasma Lipidome And Its Link To Cardiovascular Disease, Nathan O. Stitziel, Et Al.

Open Access Publications

No abstract provided.

Clinical Utility Of Advanced Microbiology Testing Tools, Melissa B. Miller, Carey-Ann D. Burnham, Et Al

Open Access Publications

No abstract provided.

Predictors Of Radiographic Osteoarthritis 2 To 3 Years After Anterior Cruciate Ligament Reconstruction: Data From The Moon On-Site Nested Cohort, Morgan H. Jones, Robert H. Brophy, Moon Knee Group, Et Al

Open Access Publications

No abstract provided.

Fatty Acid Transport Protein 4 Is Required For Incorporation Of Saturated Ultralong-Chain Fatty Acids Into Epidermal Ceramides And Monoacylglycerols, Meei-Hua Lin, Fong-Fu Hsu, Debra Crumrine, Jason Meyer, Peter M. Elias, Jeffrey H. Miner

Open Access Publications

No abstract provided.

Excitability And Irritability In Preschoolers Predicts Later Psychopathology: The Importance Of Positive And Negative Emotion Dysregulation, Alecia C Vogel, Joshua J Jackson, Deanna M Barch, Rebecca Tillman, Joan L Luby

Open Access Publications

Emotion dysregulation is a risk factor for the development of a variety of psychopathologic outcomes. In children, irritability, or dysregulated negative affect, has been the primary focus, as it predicts later negative outcomes even in very young children. However, dysregulation of positive emotion is increasingly recognized as a contributor to psychopathology. Here we used an exploratory factor analysis and defined four factors of emotion dysregulation: irritability, excitability, sadness, and anhedonia, in the preschool-age psychiatric assessment collected in a sample of 302 children ages 3-5 years enriched for early onset depression. The irritability and excitability factor scores defined in preschoolers predicted …

Current State In Scientific Publishing: Aoa Critical Issues Symposium, Jennifer Moriatis Wolf, Linda J Sandell, Seth S Leopold, Karen L Dodson

Open Access Publications

Orthopaedic surgery has a rich history of publication of the science that supports the practice of our specialty, which dates from 1887. Orthopaedic publishing has evolved since that time, expanding from print to online access, with increasing variation in publication models, including open-access journals and article repositories, and methods of information delivery that include video, data archives, and commentary. This symposium provides an overview of the changes and challenges in the publication of orthopaedic science.

Multicenter Study Demonstrates Standardization Requirements For Mold Identification By Maldi-Tof Ms, Anna F. Lau, Kaitlin F. Mitchell, Meghan A. Wallace, Carey-Ann D. Burnham, Et Al

Open Access Publications

No abstract provided.

Persistence Of Right Ventricular Dysfunction And Altered Morphometry In Asymptomatic Preterm Infants Through One Year Of Age: Cardiac Phenotype Of Prematurity, Collin T Erickson, Meghna D Patel, Swati Choudhry, Karl Stessy Bisselou, Tim Sekarski, Mary Craft, Ling Li, Afif El Khuffash, Aaron Hamvas, Shelby Kutty, Gautam K Singh, Philip T Levy

Open Access Publications

INTRODUCTION: Prematurity impacts myocardial development and may determine long-term outcomes. The objective of this study was to test the hypothesis that preterm neonates develop right ventricle dysfunction and adaptive remodelling by 32 weeks post-menstrual age that persists through 1 year corrected age.

MATERIALS AND METHODS: A subset of 80 preterm infants (born <29 weeks) was selected retrospectively from a prospectively enrolled cohort and measures of right ventricle systolic function and morphology by two-dimensional echocardiography were assessed at 32 weeks post-menstrual age and at 1 year of corrected age. Comparisons were made to 50 term infants at 1 month and 1 year of age. Sub-analyses were performed in preterm-born infants with bronchopulmonary dysplasia and/or pulmonary hypertension.

RESULT: In both term and preterm infants, right ventricle function and morphology increased over the first year (p < 0.01). The magnitudes of right ventricle function measures were lower in preterm-born infants at each time period (p < 0.01 for all) and right ventricle morphology indices were wider in all preterm infants by 1 year corrected age, irrespective of lung disease. Measures of a) right ventricle function were further decreased and b) morphology increased through 1 year in preterm infants with bronchopulmonary dysplasia and/or pulmonary hypertension (p < 0.01).

CONCLUSION: Preterm infants exhibit abnormal right ventricle performance with remodelling at 32 weeks post-menstrual age that persists through 1 year corrected age, suggesting a less developed intrinsic myocardial function response …

Three Discipline Collaborative Radiation Therapy (3dcrt) Special Debate: Equipment Development Is Stifling Innovation In Radiation Oncology, Leonard Kim, Stephanie Markovina, Samantha J Van Nest, Subarna Eisaman, Lakshmi Santanam, Julie M Sullivan, Michael Dominello, Michael C Joiner, Jay Burmeister

Open Access Publications

No abstract provided.

The Role Of Egfr Mutation As A Prognostic Factor In Survival After Diagnosis Of Brain Metastasis In Non-Small Cell Lung Cancer: A Systematic Review And Meta-Analysis, Wen-Ya Li, Ting-Ting Zhao, Hui-Mian Xu, Zhen-Ning Wang, Ying-Ying Xu, Yunan Han, Yong-Xi Song, Jian-Hua Wu, Hao Xu, Song-Cheng Yin, Xing-Yu Liu, Zhi-Feng Miao

Open Access Publications

No abstract provided.

Optimized Light Delivery Probe Using Ball Lenses For Co-Registered Photoacoustic And Ultrasound Endo-Cavity Subsurface Imaging, Guang Yang, Eghbal Amidi, Sreyankar Nandy, Atahar Mostafa, Quing Zhu

Open Access Publications

No abstract provided.

Improvement In Patient-Reported Sleep In Type 2 Diabetes And Prediabetes Participants Receiving A Continuous Care Intervention With Nutritional Ketosis, Morgan J. Siegmann, Shaminie Athinarayanan, Sarah J. Hallberg, Amy L. Mckenzie, Nasir H. Bhanpuri, Wayne W. Campbell, James P. Mccarter, Stephen D. Phinney, Jeff S. Volek, Christa J. Van Dort

Open Access Publications

No abstract provided.

The Widely Used Antimicrobial Triclosan Induces High Levels Of Antibiotic Tolerance In Vitro And Reduces Antibiotic Efficacy Up To 100-Fold In Vivo, Corey Westfall, Ana Lidia Flores-Mireles, John Isaac Robinson, Aaron J.L. Lynch, Scott Hultgren, Jeffrey P. Henderson, Petra Anne Levin

Open Access Publications

No abstract provided.

Mural Cell-Derived Laminin-Α5 Plays A Detrimental Role In Ischemic Stroke, Abhijit Nirwane, Jessica Johnson, Benjamin Nguyen, Jeffrey H. Miner, Yao Yao

Open Access Publications

No abstract provided.

Long-Term Correction Of Hemophilia B Using Adenoviral Delivery Of Crispr/Cas9, Calvin J. Stephens, Elvin J. Lauron, Elena Kashentseva, Zhi Hong Lu, Wayne M. Yokoyama, David T. Curiel

Open Access Publications

No abstract provided.

Early Emergency General Surgery Is Associated With A Higher Incidence Of Clostridium Difficile Infection, Adrian A. Coleoglou Centeno, Christopher B. Horn, Rohit K. Rasane, Jose A. Aldana, Qiao Zhang, Kelly M. Bochicchio, Grant V. Bochicchio, Obeid N. Ilahi

Open Access Publications

No abstract provided.