Digital Commons Network^™

Snake Fungal Disease In Lake Eerie Water Snakes And Its Affect On Attitude And Behavior During Treatment, Kelcie Fredrickson

Celebration of Learning

Snake fungal disease (SFD) is caused by the fungus Ophidiomyces ophiodiicola. Infection occurs when the outer skin is breached, and the organism enters the epidermis. The epidermis becomes necrotic and produces a yellow/brown crust. When the crust breaks off, ulcerations/lesions are formed along the snake’s body, head and tail. It has been found that SFD can be treated with a terbinafine nebulization treatment. Ellen Haynes, a PhD student, created a study in which 26 Lake Eerie water snakes are separated into treatment and control groups to determine the effectiveness of the nebulization treatment. Through daily observations, this research aimed …

Assessing The Rock Island Community Garden Program, Christian Elliott, Hunter Ridley, Robert Burke, Alexander Disabato, Abby Huffman, Dr. Christopher Strunk

Celebration of Learning

As part of Sustainable Working Landscapes Initiative with Augustana College’s Upper Mississippi Center, students in Urban Design and Environmental Justice (Geography 325) conducted research on Rock Island’s community garden program this fall. The City of Rock Island currently has 21 vacant-lot community gardens and plans to expand the program to 24 gardens in 2019. The purpose of this project was to develop an initial assessment of the community garden program and provide general information about the benefits of urban gardens. Students worked with Dr. Strunk to conduct a survey with current garden program participants and tested soil from 14 gardens …

Diversity Of The Brown Alga Dictyota Between Deep And Shallow Reefs Of Hawaii, Mary Ade, Rachael M. Wade, Heather L. Spalding, Alison R. Sherwood

Celebration of Learning

In this presentation, I compile the results of 10 weeks of an NSF-funded REU during the summer of 2018. This research is regarding the biodiversity of Dictyota species found in the mesophotic and shallow reef ecosystems in the Hawaiian islands.

The Role Of Atp-Binding Cassette A1 As A Susceptibility Factor In Diabetic Kidney Disease, Gloria Michelle Ducasa

Open Access Dissertations

Fibroblasts from patients with Tangier disease carrying ATP-binding cassette A1 (ABCA1) loss of function mutations are characterized by cardiolipin accumulation, a mitochondrial specific phospholipid. Suppression of ABCA1 expression occurs in glomeruli from patients with diabetic kidney disease (DKD) and in human podocytes exposed to DKD sera collected prior to the development of DKD. Furthermore, lipid metabolism dyregulation and lipid accumulation are observed in patients with DKD. However, the exact mechanisms as to how ABCA1 reduction contributes to alterations in mitochondrial lipids and function remains to be established. Therefore, the purpose of this study was to elucidate the mechanistic role reduced …

State V. Rogers Appellant's Brief Dckt. 46816

Not Reported

No abstract provided.

Usu Alum Awarded For Work In Irrigation Engineering | College Of Engineering, Utah State University

College of Engineering News

Utah State University College of Engineering alumnus Saleh Taghvaeian will receive the Larry W. Turner Young Extension Professional Award from the American Society of Agricultural and Biological Engineers. The award will be presented July 10 at the organization’s annual conference in Boston.

High‑Throughput Analysis Of Leaf Physiological And Chemical Traits With Vis–Nir–Swir Spectroscopy: A Case Study With A Maize Diversity Panel, Yufeng Ge, Abbas Atefi, Huichun Zhang, Chenyong Miao, Raghuprakash Kastoori Ramamurthy, Brandi Sigmon, Jinliang Yang, James C. Schnable

Department of Agricultural and Biological Systems Engineering: Faculty Publications

Hyperspectral reflectance data in the visible, near infrared and shortwave infrared range (VIS–NIR– SWIR, 400–2500 nm) are commonly used to nondestructively measure plant leaf properties. We investigated the usefulness of VIS–NIR–SWIR as a high-throughput tool to measure six leaf properties of maize plants including chlorophyll content (CHL), leaf water content (LWC), specific leaf area (SLA), nitrogen (N), phosphorus (P), and potassium (K). This assessment was performed using the lines of the maize diversity panel. Data were collected from plants grown in greenhouse condition, as well as in the field under two nitrogen application regimes. Leaf-level hyperspectral data were collected with …

Modulation Of Osteogenic And Myogenic Differentiation By A Phytoestrogen Formononetin Via P38mapk-Dependent Jak-Stat And Smad-1/5/8 Signaling Pathways In Mouse Myogenic Progenitor Cells, Ilavenil Soundharrajan, Da Hye Kim, Palaniselvam Kuppusamy, Ki Choon Choi

Center for Research on Environmental Disease Faculty Publications

Formononetin (FN), a typical phytoestrogen has attracted substantial attention as a novel agent because of its diverse biological activities including, osteogenic differentiation. However, the molecular mechanisms underlying osteogenic and myogenic differentiation by FN in C2C12 progenitor cells remain unknown. Therefore the objective of the current study was to investigate the action of FN on myogenic and osteogenic differentiation and its impact on signaling pathways in C2C12 cells. FN significantly increased myogenic markers such as Myogenin, myosin heavy chains, and myogenic differentiation 1 (MyoD). In addition, the expression of osteogenic specific genes alkaline phosphatase (ALP), Run-related transcription factor 2(RUNX2), and osteocalcin …

The Effects Of Using Mini Whiteboards On The Academic Performance And Engagement Of Students In A Tenth Grade Resource English/Language Arts Classroom, Elizabeth Catherine Gimbutas

Theses and Dissertations

The purpose of this study was to: (a) examine the effectiveness of mini whiteboards in increasing engagement, (b) examine the effectiveness of mini whiteboards in increasing academic achievement, and (c) determine if students in a tenth grade English/Language Arts resource center classroom are satisfied with the use of mini whiteboards. The research was conducted using an ABAB single-subject design methodology. Student achievement was evaluated through weekly assessments, while daily engagement was evaluated using interval recording in 5-minute increments. Results suggest that the use of mini whiteboards may help increase the engagement and academic achievement of students in a tenth grade …

Undying (And Undead) Modern National Myths: Cannibalism And Racial Mixture In Contemporary Brazilian Vampire Fiction, Jacob C. Brown

Alambique. Revista académica de ciencia ficción y fantasía / Jornal acadêmico de ficção científica e fantasía

Contemporary cultural media illustrates the vampire as an important symbolic figure in the Brazilian imaginary. For example, in twentieth and twenty-first century Brazilian fiction, television, and political discourse, vampires have risen from their supposedly European origins as expressions of urban decay, comic excess, and government corruption in Brazil. Beyond these representations, I focus on three contemporary novels in which the vampire also plays a starring role. O vampiro que descobriu o Brasil (1999) by Ivan Jaf, Aventuras do vampiro de Palmares (2014) by Gerson Lodi-Ribeiro, and Dom Pedro I Vampiro (2015) by Nazarethe Fonseca stand out from other creative reimaginings …

Arts Of Living On A Damaged Planet: Ghosts And Monsters Of The Anthropocene By Anna Lowenhaupt Tsing, Heather Anne Swanson, Elaine Gan, And Nils Bubandt, Randy Lee Cutler

The Goose

Review of Anna Lowenhaupt Tsing, Heather Anne Swanson, Elaine Gan, and Nils Bubandt's Arts of Living on a Damaged Planet: Ghosts and Monsters of the Anthropocene.

Molecular Specialization Of Gabaergic Synapses On The Soma And Axon In Cortical And Hippocampal Circuit Function And Dysfunction, April Contreras, Dustin J. Hines, Rochelle M. Hines

Psychology Faculty Research

The diversity of inhibitory interneurons allows for the coordination and modulation of excitatory principal cell firing. Interneurons that release GABA (γ-aminobutyric acid) onto the soma and axon exert powerful control by virtue of proximity to the site of action potential generation at the axon initial segment (AIS). Here, we review and examine the cellular and molecular regulation of soma and axon targeting GABAergic synapses in the cortex and hippocampus. We also describe their role in controlling network activity in normal and pathological states. Recent studies have demonstrated a specific role for postsynaptic dystroglycan in the formation and maintenance of cholecystokinin …

Is Intimate Partner Violence A Risk Factor For Cardiovascular Disease In Women? A Review Of The Preponderance Of The Evidence, Rose Eva Constantino, Alona D. Angosta, Andrew Thomas Reyes, Brayden Kameg, Linden Wu, Jordan Cobb, Vivian Hui, Daisy Palompon, Reema Safadi, Mayada Daibes, Elizabeth Schlenk

Nursing Faculty Research

This paper examines the relationship between intimate partner violence (IPV) experience in women and cardiovascular disease (CVD), and determines if there is a preponderance of literature evidence. Research is reviewed dealing with the different biopsychosocial factors affecting the relationship between IPV and CVD. As a result of our review, we propose a framework on the biopsychosocial pathway of IPV as a risk factor of CVD of women. Our proposed framework portrays how IPV experiences contribute to long-term biopsychosocial changes that increase the risk of CVD among female victims of IPV. These biopsychosocial changes include chronic inflammation and hypothalamus-pituitary-adrenal axis dysfunction, …

Volume 56, Number 45: June 26, 2019, University Of North Dakota

University Letter Archive

No abstract provided.

Nitrogen Heterocycles Form Peptide Nucleic Acid Precursors In Complex Prebiotic Mixtures, Laura E. Rodriguez, Christopher H. House, Karen E. Smith, Melissa R. Roberts, Michael P. Callahan

Chemistry and Biochemistry Faculty Publications and Presentations

The ability to store information is believed to have been crucial for the origin and evolution of life; however, little is known about the genetic polymers relevant to abiogenesis. Nitrogen heterocycles (N-heterocycles) are plausible components of such polymers as they may have been readily available on early Earth and are the means by which the extant genetic macromolecules RNA and DNA store information. Here, we report the reactivity of numerous N-heterocycles in highly complex mixtures, which were generated using a Miller-Urey spark discharge apparatus with either a reducing or neutral atmosphere, to investigate how N-heterocycles are modified under plausible prebiotic …

Competitive Frontoparietal Interactions Mediate Implicit Inferences, Martijn E. Wokke, Tony Ro

Publications and Research

Frequent experience with regularities in our environment allows us to use predictive information to guide our decision process. However, contingencies in our environment are not always explicitly present and sometimes need to be inferred. Heretofore, it remained unknown how predictive information guides decision-making when explicit knowledge is absent and how the brain shapes such implicit inferences. In the present experiment, 17 human participants (9 females) performed a discrimination task in which a target stimulus was preceded by a predictive cue. Critically, participants had no explicit knowledge that some of the cues signaled an upcoming target, allowing us to investigate how …

Wmu Board Of Trustees Formal Session June 26, 2019, Wmu Board Of Trustees

WMU Board of Trustees Meetings

• Acceptance of the Agenda
• Approval of the Minutes
• Remarks by the Chair
• Remarks by the President
• Comments by the Faculty Senate President
• Comments by the Western Student Association President
• Comments by the Graduate Student Association President
• Greenleaf Scholar Showcase
• Public Comments Regarding Action Items
• Tuition and Fees
• University Budget for 2019-2020
• Academic Tenure and Promotion
• Michigan State Employees Association (MSEA) Labor Agreement
• Establishment of the WMU Business, Technology, and Research Park 2
• Lease Agreement Renewal between WMU and WMU AAUP
• Series 2019 General Revenue Bonds
• Consent Items
• General Public Comments

The Long Trajectory, Unh Communications And Public Affairs

UNH Today Archive

No abstract provided.

Effects Of Single And Integrated Water, Sanitation, Handwashing, And Nutrition Interventions On Child Soil-Transmitted Helminth And Giardia Infections: A Cluster-Randomized Controlled Trial In Rural Kenya, Amy J. Pickering, Sammy M. Njenga, Lauren Steinbaum, Jenna Swarthout, Audrie Lin, Benjamin F. Arnold, Christine P. Stewart, Holly N. Dentz, Maryanne Mureithi, Benard Chieng, Marlene Wolfe, Ryan Mahoney, Jimmy Kihara, Kendra Byrd, Gouthami Rao, Theodora Meerkerk, Priscah Cheruiyot, Marina Papaiakovou, Nils Pilotte, Steven A. Williams, John M. Colford Jr., Clair Null

Biological Sciences: Faculty Publications

Helminth and protozoan infections affect more than 1 billion children globally. Improving water quality, sanitation, handwashing, and nutrition could be more sustainable control strategies for parasite infections than mass drug administration, while providing other quality of life benefits.

The Developmental And Behavioral Effects Of Δ9-Tetrahydrocannabinol On A Spastic Mutant, Victoria Mendiola

Master of Science in Integrative Biology Theses

Hyperekplexia is a neurological disorder affecting infants and can be characterized by excessive startle reactions in response to unexpected stimuli. This disease can be modeled in zebrafish in the bandoneon (beo) mutant, where the glrbbmutation results in glycine receptor (GLYR) loss of function glycine receptors and ultimately, improper inhibitory signaling. Though hyperekplexia is a glycinergic-based signaling disorder, disease symptoms are often alleviated with GABA-agonistic benzodiazepines. Exogenous cannabinoids also modulate GABAergic signaling, and THC, one of the natural compounds that prompted the discovery of the endocannabinoid system mimics the effects of endogenous cannabinoids at endocannabinoid and non-cannabinoid sites in the …

Changing High School Science Teacher Beliefs On Student Voice Through Action Research, Katie Laux

USF Tampa Graduate Theses and Dissertations

The purpose of this dissertation research was to explore how engagement in action research influenced high school science teachers’ beliefs and classroom practices related to student voice and participation. This included exploring any affordances or obstacles they experienced with attempting to increase student voice and participation in their classrooms. I facilitated individual action research projects with the teachers, and they were able to discuss individual action research plans and share ideas with colleagues. Four high school science teachers began this research. While all four teachers were selected as cases, only two of the teachers designed and followed through with their …

Synthesis, Discovery And Delivery Of Therapeutic Natural Products And Analogs, Zachary P. Shultz

USF Tampa Graduate Theses and Dissertations

Small molecule drug discovery relies heavily on synthetic organic chemistry to develop novel chemical entities that elicit desirable therapeutic effects. The development of targeted chemical syntheses is of paramount importance to access molecules for biological evaluation and is usually considered the bottleneck in most drug discovery campaigns. Targets for chemical syntheses commonly draw inspiration from molecules of natural origin. Nature harbors a wealth of chemical diversity that has established itself over millions of years through chemical and biological evolution. Organisms have an inherent ability to protect themselves from predators and harmful environments. In doing so, many of them evolve to …

Characterization Of The Integrated Signaling Network Of Burkholderia Glumae For The Regulation Of Virulence-Related Function In The Bacterial Pathogenesis Of Rice Plants, Tiago De Paula Lelis

LSU Doctoral Dissertations

Bacterial panicle blight of rice (BPB) caused by Burkholderia glumaeis a major bacterial disease of rice in many rice-producing areas worldwide. Managing the disease is still very difficult due to the lack of effective methods. B. glumaestrains show phenotypic and genomic variations; however, little variation was detected in the known virulence-related genes. In the present study, the complete genome of B. glumae257sh-1, a natural avirulent strain, was sequenced and analyzed. Several spontaneous mutations in the regulatory genes of these avirulent strains were identified. Presumably, the accumulation of these mutations can have a negative effect on the normal …

The Parthenon, June 26, 2019, Hanna Pennington

The Parthenon

The Parthenon, Marshall University’s student newspaper, was published by students Monday through Friday during the regular semester and weekly on Thursdays during the summer. Due to budgetary constraints, beginning with the 2018 Fall semester, the newspaper is only published one day a week. The editorial staff is responsible for the news and the editorial content.

Transferrin-Bearing Liposomes Entrapping Plumbagin For Targeted Cancer Therapy, Intouch Sakpakdeejaroen, Sukrut Somani, Partha Laskar, Margaret Mullin, Christine Dufès

School of Medicine Publications

The therapeutic potential of plumbagin, a naphthoquinone extracted from the officinal leadwort with anticancer properties, is hampered by its failure to specifically reach tumours at a therapeutic concentration after intravenous administration, without secondary effects on normal tissues. Its use in clinic is further limited by its poor aqueous solubility, its spontaneous sublimation, and its rapid elimination in vivo. We hypothesize that the entrapment of plumbagin within liposomes grafted with transferrin, whose receptors are overexpressed on many cancer cells, could result in a selective delivery to tumours after intravenous administration. The objectives of this study were therefore to prepare and …

What Can You See? Identifying Cues On Internal States From The Movements Of Natural Social Interactions, Me Bartlett, Cer Edmunds, T Belpaeme, S Thill, S Lemaignan

School of Engineering, Computing and Mathematics

No abstract provided.

Pparg Signaling In The Nucleus Accumbens Regulates Mesolimbic Dopamine Activity, Tony Jung, Roger Hudson, Hanna Szkudlarek, Walter Rushlow, Steve Laviolette

Western Research Forum

Background: The mesolimbic dopamine system consists of dopamine neuron projections from the ventral tegmental area (VTA) to the nucleus accumbens (NAc). The NAc regulates VTA dopamine release through inhibitory GABA projections to the VTA. Hyperactive mesolimbic dopamine signaling is implicated in anxiety. Cannabidiol, a compound found in cannabis, demonstrates promising therapeutic potential for anxiety through the regulation of the mesolimbic dopamine system. Previous studies have revealed that cannabidiol infusions into the NAc decreases mesolimbic dopamine activity - potentially through the inhibitory GABA signaling to the VTA. However, the receptor mechanism in the NAc through which CBD produces its effects is …

How Dumbledore Saved Europe: A Comparison Of Fascist Rhetoric In European History And In The Harry Potter Franchises, Emma Pederson, Natalie Rice

MAD-RUSH Undergraduate Research Conference

In recent years, the popularity of the Harry Potter franchise has seen a resurgence with the release of the first two Fantastic Beasts films and accompanying screenplays. As parallels have been drawn between Voldemort’s Death Eaters and Nazis, it is time to examine the relationship between Gellert Grindelwald and real-life fascists. Through such a comparison, we can see common rhetoric in both real and fictional fascism.

Gellert Grindelwald and Albus Dumbledore have not only a Nazi-like goal of racial purity, but employ Nazi-like language to defend themselves. Related fascist rhetoric is woven throughout other European history, particularly in the dialogues …

Blood, Meth, And Tears: The Super Soldiers Of World War Ii, Nicholas Racine

MAD-RUSH Undergraduate Research Conference

Day and night, soldiers in World War II were physically and mentally strained by fatigue and psychiatric distress. Consequently, many soldiers were left exhausted and demoralized. War efforts hinged on soldiers succeeding in missions, thus a fast-acting solution was needed. Development of the psychostimulant drugs Benzedrine and Pervitin in the 1920s and 30s spurred enthusiasm among scientists, the media, the public, and various governments. Potent and powerful, these drugs exert effects that promote wakefulness, elevated mood, and improved field performance. Governments quickly began researching use of stimulants to improve their war efforts. By the early 40s, both drugs had millions …

Research Panel: Variation In Women Attaining Full Professorships At Research Universities And Non-Tenured Faculty Systems In The Us And Abroad, Sandra Darkey

Journal of Collective Bargaining in the Academy

Structural/Organizational Determinants of Variations in Women Attaining the Full Professorship at Research Universities