Open Access. Powered by Scholars. Published by Universities.®

Digital Commons Network™

Open Access. Powered by Scholars. Published by Universities.®

2019

Discipline
Institution
Keyword
Publication
Publication Type
File Type

Articles 7111 - 7140 of 29591

Full-Text Articles in Entire DC Network

The Station “Scientist”: Examining The Impact Of Race, Sex, And Education Of Broadcast Meteorologists On Credibility, Trust, And Information Retention, Adam M. Rainear Aug 2019

The Station “Scientist”: Examining The Impact Of Race, Sex, And Education Of Broadcast Meteorologists On Credibility, Trust, And Information Retention, Adam M. Rainear

Doctoral Dissertations

Broadcast meteorologists hold a set of skills unique in a newsroom. Not only must a broadcast meteorologist utilize communication skills similar to that of a newscaster, they are also typically versed in some physical science. In addition, the field of meteorology has an unfortunate disparity when examining job statistics as they relate to race and biological sex. Generally speaking, men outnumber women in broadcast television positions three to one, and minorities are often outnumbered or excluded from coverage altogether. Drawing on Uses and Gratifications and Media System Dependency Theory, this project examines the effects of race, biological sex, and forecaster …


Toxoplasma Gondii Infection Drives Conversion Of Nk Cells Into Ilc1-Like Cells, Eugene Park, Swapneel Patel, Qiuling Wang, Prabhakar Andhey, Konstantin Zaitsev, Sophia Porter, Maxwell Hershey, Michael Bern, Beatrice Plougastel-Douglas, Patrick Collins, Marco Colonna, Kenneth M. Murphy, Eugene Oltz, Maxim Artyomov, L David Sibley, Wayne M. Yokoyama Aug 2019

Toxoplasma Gondii Infection Drives Conversion Of Nk Cells Into Ilc1-Like Cells, Eugene Park, Swapneel Patel, Qiuling Wang, Prabhakar Andhey, Konstantin Zaitsev, Sophia Porter, Maxwell Hershey, Michael Bern, Beatrice Plougastel-Douglas, Patrick Collins, Marco Colonna, Kenneth M. Murphy, Eugene Oltz, Maxim Artyomov, L David Sibley, Wayne M. Yokoyama

Open Access Publications

Innate lymphoid cells (ILCs) were originally classified based on their cytokine profiles, placing natural killer (NK) cells and ILC1s together, but recent studies support their separation into different lineages at steady-state. However, tumors may induce NK cell conversion into ILC1-like cells that are limited to the tumor microenvironment and whether this conversion occurs beyond this environment remains unknown. Here, we describe


Viral Community Assembly In Puerto Rican Bats, Anna Sjodin Aug 2019

Viral Community Assembly In Puerto Rican Bats, Anna Sjodin

Doctoral Dissertations

Viruses are the most abundant biological entity on Earth, yet little is known about the factors driving their abundance, frequency of occurrence, and distribution in non-human hosts. Most emerging infectious diseases of humans originate in wildlife, up to a quarter of which are caused by viruses, creating an urgent need to broaden understanding of viral systems. With its theoretical depth, ecology can provide mechanistic insights about viral diversity, with broad implications for public health and wildlife conservation. Unfortunately, few datasets exist that allow a thorough exploration of viral ecology, and the process of defining viral species can prohibit timely conclusions. …


What We (Don’T) Know About Global Plant Diversity, William K. Cornwell, William D. Pearse, Rhiannon L. Dalrymple, Amy E. Zanne Aug 2019

What We (Don’T) Know About Global Plant Diversity, William K. Cornwell, William D. Pearse, Rhiannon L. Dalrymple, Amy E. Zanne

Ecology Center Publications

The era of big biodiversity data has led to rapid, exciting advances in the theoretical and applied biological, ecological and conservation sciences. While large genetic, geographic and trait databases are available, these are neither complete nor random samples of the globe. Gaps and biases in these databases reduce our inferential and predictive power, and this incompleteness is even more worrisome because we are ignorant of both its kind and magnitude. We performed a comprehensive examination of the taxonomic and spatial sampling in the most complete current databases for plant genes, locations and functional traits. To do this, we downloaded data …


Workshop On Convergence In Biological Engineering, Keith Roper Aug 2019

Workshop On Convergence In Biological Engineering, Keith Roper

Funded Research Records

No abstract provided.


Newsroom, Georgia Southern University Aug 2019

Newsroom, Georgia Southern University

Newsroom (2006-2023)

  • Georgia Southern student, faculty research shows surprising findings about pet ownership, potential health risks for women
  • Georgia Southern helping rural teachers introduce renewable energy into classrooms


Effects Of Adrenergic Or A Combination Of Adrenergic And Opioid Drugs On Assessments Of Insulin Sensitivity In Mares, Lauren Kerrigan Aug 2019

Effects Of Adrenergic Or A Combination Of Adrenergic And Opioid Drugs On Assessments Of Insulin Sensitivity In Mares, Lauren Kerrigan

LSU Master's Theses

Excitement is a problem when conducting endocrine tests on fractious horses. Epinephrine (EPI), for example, was shown to obliterate the insulin-induced decrease in blood glucose concentrations. Sedation may be a solution; however, perturbation of results may preclude useful information. The objectives of the four experiments presented herein were 1) to determine the effects of EPI on insulin response to glucose infusion (IR2G), 2) to assess the effects of the α-adrenergic sedative, detomidine (DET), alone or in combination with the opioid agonist, butorphanol (BUT), on IR2G and glucose response to insulin (GR2I), and 3) to assess the effects of BUT alone …


Measurements Of N₂O And Sf₆ Mole Fraction And N₂O Isotopic Composition Between 1978 And 1997 In Archived Air Samples From Cape Meares, Oregon, Terry Clinton Rolfe Aug 2019

Measurements Of N₂O And Sf₆ Mole Fraction And N₂O Isotopic Composition Between 1978 And 1997 In Archived Air Samples From Cape Meares, Oregon, Terry Clinton Rolfe

Dissertations and Theses

Nitrous oxide (N2O) is the third most important greenhouse gas (GHG) behind carbon dioxide (CO2) and methane (CH4). Sulfur hexafluoride (SF6) does not add significantly to climate forcing by itself due to the low concentration in the atmosphere; however, it is one of the most powerful GHG known. Measurements of atmospheric N2O made prior to mid-1990 have larger uncertainties than later periods due to advancements made in gas chromatography (GC) methods. Few atmospheric SF6 measurements pre-1990 exist, especially in the northern hemisphere. Archived samples may be analyzed using updated …


The First Vega Ride-Share Mission Flight, Fabio Caramelli, Francois Battie, Aldo Scaccia, S. Corbo, A. Dalloneau, F. Fabiani, Angelo Fontana, M. Mariani, P. Guerrieri, Augusto Cramarossa, Alessandro Gabrielli Aug 2019

The First Vega Ride-Share Mission Flight, Fabio Caramelli, Francois Battie, Aldo Scaccia, S. Corbo, A. Dalloneau, F. Fabiani, Angelo Fontana, M. Mariani, P. Guerrieri, Augusto Cramarossa, Alessandro Gabrielli

Small Satellite Conference

The first European ride-share mission will be carried out by the Vega launch system in September 2019. The VEGA PoC (Proof of Concept) flight using the SSMS (Small Satellite Mission Service) hardware was conceived in the context of ESA LLL Initiative. This paper reports on the highlights of the preparation of the first European rideshare mission with Vega launcher and on the development of the related launch system.

Based on Vega flights accumulated experience, the development of multi-Payload mission concept started from analysis of the activities currently foreseen to fly a single payload mission adapted to the needs of multi …


Meet Marin Sardy, Mals ’07, Sabine Hoskinson Aug 2019

Meet Marin Sardy, Mals ’07, Sabine Hoskinson

CLAMANTIS: The MALS Journal

No abstract provided.


The Effects Of A Topical Chinese Herbal Medicine In Skin Wound Healing, Marquese Noel-Mccormick Aug 2019

The Effects Of A Topical Chinese Herbal Medicine In Skin Wound Healing, Marquese Noel-Mccormick

Open Access Theses

Wound care and the associated morbidity and mortality as well as high cost continue to pose major challenges in medicine and society, especially due to chronic non-healing wounds. In recent years, alternative medicine has become increasingly used for the chronic wounds due to its natural origins, weaker side effects, and low cost compared to synthetic pharmaceutical drugs. This study tested the effects of a topical Chinese herbal medicine used for the chronic wounds, called “Healing Paste,” on the functions of skin cells during the wound healing process as well different strains of bacteria that commonly colonize chronic wounds. The “Healing …


An Effective Electric Dipole Model For Voltage-Induced Gating Mechanism Of Lysenin, Eric Krueger, Daniel Fologea Aug 2019

An Effective Electric Dipole Model For Voltage-Induced Gating Mechanism Of Lysenin, Eric Krueger, Daniel Fologea

Physics Faculty Publications and Presentations

Lysenin is a pore-forming toxin, which self-inserts open channels into sphingomyelin containing membranes and is known to be voltage regulated. The mechanistic details of its voltage gating mechanism, however, remains elusive despite much recent efforts. Here, we have employed a novel combination of experimental and computational techniques to examine a model for voltage gating, that is based on the existence of an “effective electric dipole” inspired by recent reported structures of lysenin. We support this mechanism by the observations that (i) the charge-reversal and neutralization substitutions in lysenin result in changing its electrical gating properties by modifying the strength of …


The Influence Of Signaling Conspecific And Heterospecific Neighbors On Eavesdropper Pressure, Paula A. Trillo, Christopher S. Benson, Michael S. Caldwell, Tiffany L. Lam, Oliver H. Pickering, David M. Logue Aug 2019

The Influence Of Signaling Conspecific And Heterospecific Neighbors On Eavesdropper Pressure, Paula A. Trillo, Christopher S. Benson, Michael S. Caldwell, Tiffany L. Lam, Oliver H. Pickering, David M. Logue

Biology Faculty Publications

The study of tradeoffs between the attraction of mates and the attraction of eavesdropping predators and parasites has generally focused on a single species of prey, signaling in isolation. In nature, however, animals often signal from mixed-species aggregations, where interactions with heterospecific group members may be an important mechanism modulating tradeoffs between sexual and natural selection, and thus driving signal evolution. Although studies have shown that conspecific signalers can influence eavesdropper pressure on mating signals, the effects of signaling heterospecifics on eavesdropper pressure, and on the balance between natural and sexual selection, are likely to be different. Here, we review …


The Path To God Is Through The Heart: Metaphoric Self-Location As A Predictor Of Religiosity, Adam K. Fetterman, Jacob Juhl, Brian P. Meier, Andrew Abeyta, Clay Routledge, Michael D. Robinson Aug 2019

The Path To God Is Through The Heart: Metaphoric Self-Location As A Predictor Of Religiosity, Adam K. Fetterman, Jacob Juhl, Brian P. Meier, Andrew Abeyta, Clay Routledge, Michael D. Robinson

Psychology Faculty Publications

Metaphors linking the heart to warm intuition and the head to cold rationality may capture important differences between people because some locate the self in the heart and others locate the self in the head. Five studies (total N = 2575) link these individual differences to religious beliefs. Study 1 found that religious beliefs were stronger among heart-locators than head-locators. Studies 2 and 3 replicated this relationship in more diverse samples. Studies 4 and 5 focused on questions of mediation. Heart-locators believed in God to a greater extent partly because of empathy-related processes (Study 4) and partly because they tended …


Domestic Evolution: Amending The United States Refugee Definition Of The Ina To Include Environmentally Displaced Refugees, Barbara Mcisaac Aug 2019

Domestic Evolution: Amending The United States Refugee Definition Of The Ina To Include Environmentally Displaced Refugees, Barbara Mcisaac

University of Miami Race & Social Justice Law Review

No abstract provided.


Innovative Tool Gives Researchers New Look At The Nasal Airway In Cf Patients, Staff Aug 2019

Innovative Tool Gives Researchers New Look At The Nasal Airway In Cf Patients, Staff

Browse All News

No abstract provided.


Volume 56, Number 51: August 07, 2019, University Of North Dakota Aug 2019

Volume 56, Number 51: August 07, 2019, University Of North Dakota

University Letter Archive

No abstract provided.


Synthesis And Evaluations Of “1,4-Triazolyl Combretacoumarins” And Desmethoxy Analogs, Tashrique A. Khandaker, Jessica D. Hess, Renato Aguilera, Graciela Andrei, Robert Snoeck, Dominique Schols, Padmanava Pradhan, Mahesh K. Lakshman Aug 2019

Synthesis And Evaluations Of “1,4-Triazolyl Combretacoumarins” And Desmethoxy Analogs, Tashrique A. Khandaker, Jessica D. Hess, Renato Aguilera, Graciela Andrei, Robert Snoeck, Dominique Schols, Padmanava Pradhan, Mahesh K. Lakshman

Publications and Research

1,4-Triazolyl combretacoumarins have been prepared by linking the trimethoxyarene unit of combretastatin A4 with coumarins, via a 1,2,3-triazole. For this, 4-azidocoumarins were accessed by a sequential two-step, one-pot reaction of 4-hydroxycoumarins with (benzotriazol-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate (BOP), followed by reaction with NaN3. In the reaction with BOP, a coumarin-derived phosphonium ion intermediate seems to form, leading to an O4-(benzotriazolyl)coumarin derivative. For the CuAAC reaction of azidocoumarins with 5-ethynyl-1,2,3-trimethoxybenzene, catalytic [(MeCN)4Cu]PF6 in CH2Cl2/MeOH with 2,6-lutidine, at 50 oC, was suitable. The 4-azidocoumarins were less reactive as compared to PhN3 and …


Oxytocin Receptor Genotype And Serotonin Transporter Genotype As Mediators Of Social Behavior: A Rhesus Macaque Model, Ryno Kruger Aug 2019

Oxytocin Receptor Genotype And Serotonin Transporter Genotype As Mediators Of Social Behavior: A Rhesus Macaque Model, Ryno Kruger

Undergraduate Honors Theses

Studies suggest that sociality plays a major role in physical and mental health, with loneliness, hostility, and aggression contributing to ill health. Genetic variation functions as a foundational basis for positive sociality, as well as antisocial behaviors such as social alienation and aggression. It is widely believed that the central serotonin and oxytocin systems are two neurotransmitter systems that play important roles in sociality and antisocial behavior. In this study, we investigate the genetic impact of the serotonin transporter gene (SERT) and a recently discovered oxytocin receptor (OXTR) gene on social isolation and antisocial behavior using a rhesus monkey model …


Parr Going The Distance: How Migratory Difficulty Influences Red Muscle Lipid Storage In Juvenile Oncorhynchus Mykiss, Emily Jean Morse Aug 2019

Parr Going The Distance: How Migratory Difficulty Influences Red Muscle Lipid Storage In Juvenile Oncorhynchus Mykiss, Emily Jean Morse

Dissertations and Theses

Adult salmonid populations embarking on difficult migrations have evolved to store more somatic energy prior to river entry. While it is known that lipids are the primary fuel for endurance swimming in fish, uncertainty still surrounds how these mechanisms are utilized by juvenile fish during seaward migration. A key phase in salmonid migration is the preparatory season of feeding and growth before swimming downstream. During this period, juvenile fish build somatic fuel stores through dietary uptake. Intestinal microbiota of steelhead trout (Oncorhynchus mykiss) vary drastically across their geographic range, with significant differences in the coastal and inland subspecies' …


Further Analyses Of The Safety Of Verubecestat In The Phase 3 Epoch Trial Of Mild-To-Moderate Alzheimer’S Disease, Michael F. Egan, Yuki Mukai, Tiffini Voss, James Kost, Julie Stone, Christine Furtek, Erin Mahoney, Jeffrey L. Cummings, Pierre N. Tariot, Paul S. Aisen, Bruno Vellas, Christopher Lines, David Michaelson Aug 2019

Further Analyses Of The Safety Of Verubecestat In The Phase 3 Epoch Trial Of Mild-To-Moderate Alzheimer’S Disease, Michael F. Egan, Yuki Mukai, Tiffini Voss, James Kost, Julie Stone, Christine Furtek, Erin Mahoney, Jeffrey L. Cummings, Pierre N. Tariot, Paul S. Aisen, Bruno Vellas, Christopher Lines, David Michaelson

Integrated Health Sciences Faculty Research

Background: Verubecestat, a BACE1 inhibitor that reduces Aβ levels in the cerebrospinal fluid of humans, was not effective in a phase 3 trial (EPOCH) of mild-to-moderate AD and was associated with adverse events. To assist in the development of BACE1 inhibitors, we report detailed safety findings from EPOCH. Methods: EPOCH was a randomized, double-blind, placebo-controlled 78-week trial evaluating verubecestat 12 mg and 40 mg in participants with mild-to-moderate AD diagnosed clinically. The trial was terminated due to futility close to its scheduled completion. Of 1957 participants who were randomized and took treatment, 652 were assigned to verubecestat 12 mg, 652 …


Edsup! Um Faculty Launch Early Childhood Podcast, Andrew M. Abernathy Aug 2019

Edsup! Um Faculty Launch Early Childhood Podcast, Andrew M. Abernathy

University of Mississippi News

Series dedicated to 'children and those who care for them'


Executive Committee & Cabinet Minutes August 2019, Uno Faculty Senate Aug 2019

Executive Committee & Cabinet Minutes August 2019, Uno Faculty Senate

Faculty Senate Minutes

These are the official minutes of the Faculty Senate Executive Council Meetings at the University of Nebraska - Omaha (UNO) for Academic year 2019-2020. Minutes are not posted until officially approved by the Executive Council at the following meeting. Minutes are archived yearly within the UNO Library Archives.


Evaluating The Efficacy Of Point-Of-Use Water Filtration Units In Fiji, Nathan L. Tintle, Adam Heynen, Kristin Van De Griend, Rachel Ulrich, Matthew Ojo, Emma Boven, Sarah Brokus, Randall Wade, Aaron A. Best Aug 2019

Evaluating The Efficacy Of Point-Of-Use Water Filtration Units In Fiji, Nathan L. Tintle, Adam Heynen, Kristin Van De Griend, Rachel Ulrich, Matthew Ojo, Emma Boven, Sarah Brokus, Randall Wade, Aaron A. Best

Faculty Work Comprehensive List

Background: To develop and evaluate a strategy for reducing the prevalence and impact of waterborne disease, a water quality intervention was developed for Fiji by Give Clean Water, Inc. in partnership with the Fiji Ministry of Health. Residents were provided and trained on how to use a Sawyer® PointONE™ filter, while also being taught proper handwashing techniques. At the time of the filter installation, all households were surveyed inquiring about the prior 2- to 4-week period. Households were measured a second time between 19 and 225 days later (mean = 66 days).

Results: To date, five economic and health outcomes …


Joy Of Discovery, Eric F. Spina Aug 2019

Joy Of Discovery, Eric F. Spina

President's Blog: From the Heart

Christian S. Hemsath stood behind a grand piano in the Sears Recital Hall, gracefully brushing his fingers across the keys while he talked about similar patterns he discovered in the seemingly opposite fields of math and music.


Characterization Of Endothelial Nitric Oxide Synthase Serine-600 Phosphorylation, Kevin Patel Aug 2019

Characterization Of Endothelial Nitric Oxide Synthase Serine-600 Phosphorylation, Kevin Patel

Master of Science in Chemical Sciences Theses

Endothelial nitric oxide synthase (eNOS) is part of a family of three nitric oxide synthase (NOS) enzymes that catalyze the production of nitric oxide (NO). NO is a gaseous, free-radical signaling molecule that has a variety of cellular and physiological functions that range from maintaining cardiovascular homeostasis to neurotransmission. The function of NO greatly depends on the concentration and is cell type specific. eNOS is the most regulated of the three NOS isoforms and the mechanisms of regulation can be through protein-protein interactions and posttranslational modifications. A connection with eNOS and the cell cycle has begun to form with recent …


The Linc Complex, Mechanotransduction, And Mesenchymal Stem Cell Function And Fate, Tasneem Bouzid, Eunju Kim, Brandon D. Riehl, Amir Monemian Esfahani, Jordan Rosebohm, Ruiguo Yang, Bin Duan, Jung Yul Lim Aug 2019

The Linc Complex, Mechanotransduction, And Mesenchymal Stem Cell Function And Fate, Tasneem Bouzid, Eunju Kim, Brandon D. Riehl, Amir Monemian Esfahani, Jordan Rosebohm, Ruiguo Yang, Bin Duan, Jung Yul Lim

Department of Mechanical and Materials Engineering: Faculty Publications

Mesenchymal stem cells (MSCs) show tremendous promise as a cell source for tissue engineering and regenerative medicine, and are understood to be mechanosensitive to external mechanical environments. In recent years, increasing evidence points to nuclear envelope proteins as a key player in sensing and relaying mechanical signals in MSCs to modulate cellular form, function, and differentiation. Of particular interest is the Linker of Nucleoskeleton and Cytoskeleton (LINC) complex that includes nesprin and SUN. In this review, the way in which cells can sense external mechanical environments through an intact nuclear envelope and LINC complex proteins will be briefly described. Then, …


Modeling Composite Cytoskeletal Networks Using Effective Medium Theory, Jacob Wales Aug 2019

Modeling Composite Cytoskeletal Networks Using Effective Medium Theory, Jacob Wales

Theses

The mechanical response of most living cells arises from their cytoskeleton, a polymeric scaffold made of different types of biopolymers and associated crosslinking proteins.

We used rigidity percolation theory to devise a set of models using an effective medium approach to study the mechanical properties of cytoskeleton-like networks. We first successfully recreated a model which obtains the mechanical response of a disordered network of a single filament type, given the constitutive material properties of individual filaments and the network geometry. In this model, wherever two filaments cross they are crosslinked together, and these crosslinkers allow for energy free rotation of …


Phenomenological Approach Toward Understanding The Experience Of Men Living With Breast Cancer, Lisa Nemchek Aug 2019

Phenomenological Approach Toward Understanding The Experience Of Men Living With Breast Cancer, Lisa Nemchek

Doctoral Dissertations

Background: Men account for approximately 1% of the total population of breast cancer. Men are generally diagnosed at much later stages of breast cancer than women. Evidence shows the earlier breast cancer is detected, the better the outcome.

Objective: The aim of this study is to describe the meanings of men living with breast cancer.

Method: Descriptive phenomenology was the research design used. An international sample of 10 men participated in this study. Men were asked, "Please describe for me all your experience living with breast cancer. Please describe all your thoughts, feelings, and perceptions that you wish to share. …


The Role Of A Permeable Sand Column In Modifying Tidal Creek Geochemistry And Land-Derived Inputs To The Coastal Ocean, Nicholas Anthony Legut Aug 2019

The Role Of A Permeable Sand Column In Modifying Tidal Creek Geochemistry And Land-Derived Inputs To The Coastal Ocean, Nicholas Anthony Legut

Electronic Theses and Dissertations

The impairment of regional water quality in Long Bay is an episodic occurrence that has been documented for over a decade. According to one explanation, the occurrence of these events is hypothesized to be the combination of local, terrestrially derived inputs and water-column stratification in the nearshore zone. A portion of these inputs may discharge as surface run-off through estuaries ending in sandy transitional environments termed "swashes". An investigation into the fate of land-derived materials through swashes utilize a linear conservative mixing model to describe the non-conservative behavior of materials in the overlying water and pore-water. This model relies on …