Digital Commons Network^™

A Terrestrial Reconstruction Of Gona, Ethiopia Before And During The African Humid Period, Marie N. White, Gary E. Stinchcomb

Posters-at-the-Capitol

The African Humid Period (AHP) resulted in more humid conditions across Northern and Eastern Africa from 15 to 5 thousand years ago (ka). This wetter climate affected flora, fauna and the Homo sapiens living in East Africa. The lack of terrestrial paleoenvironmental reconstructions is a problem in East Africa, especially during the AHP, where most are done utilizing lacustrine or marine proxies. In the case of Gona, Ethiopia, terrestrial proxies are desired due to the rich archaeological and fossil concentrations that occur in the area. Paleosols provide more direct, localized reconstructions that provide context for these finds. This study utilizes …

Production Performance Of Freshwater Prawn (Macrobrachium Rosenbergii) Reared At Two Stocking Densities And Fed Only Wet Brewers Grains, Shawn Coyle, Kalvin Rucker

Posters-at-the-Capitol

Production performance of freshwater prawn (Macrobrachium rosenbergii) reared at two stocking densities and fed only wet brewers grains. KALVIN RUCKER, SHAWN COYLE, and JAMES TIDWELL, Kentucky State University, College of Agriculture, Communities and the Environment, Frankfort, KY 40601.

Successful freshwater prawn (Macrobrachium rosenbergii) culture is based upon producing high-value outputs (prawn) from low-cost inputs (feed[CM1] ). Sinking catfish feed have traditionally been the recommended feed. The use of locally available by-products has the potential to reduce production costs. Wet brewers grains (WBG) are the solid residue left after the processing of cereal grains to produce …

Egrove Turns 1, Michelle Emanuel

Open Access Week

A look at how eGrove, UM's institutional repository, has grown during its first year.

Data From: Wildfire, National Park Visitation, And Changes In Regional Economic Activity, Man-Keun Kim, Paul M. Jakus

Browse all Datasets

Data from the associated paper. Abstract from paper below:

The visibility, safety, and health effects of seasonal wildfires may affect recreational visits to national parks (NPs), even if fires occur outside of park boundaries. This study statistically quantifies the effect of nearby wildfire on tourist flows to each of Utah's five NPs (Arches, Bryce Canyon, Canyonlands, Capitol Reef, and Zion). Using monthly data from May 1993 to December 2015, we empirically link wildfire activities (measured as monthly area burned within 80 km, 160 km, and 320 km radii) to monthly visits to each national park. Results show that …

Invertebrate Retinal Progenitors As Regenerative Models In A Microfluidic System, Caroline D. Pena, Stephanie Zhang, Robert Majeska, Tadmiri Venkatesh, Maribel Vazquez

Publications and Research

Regenerative retinal therapies have introduced progenitor cells to replace dysfunctional or injured neurons and regain visual function. While contemporary cell replacement therapies have delivered retinal progenitor cells (RPCs) within customized biomaterials to promote viability and enable transplantation, outcomes have been severely limited by the misdirected and/or insuffcient migration of transplanted cells. RPCs must achieve appropriate spatial and functional positioning in host retina, collectively, to restore vision, whereas movement of clustered cells differs substantially from the single cell migration studied in classical chemotaxis models. Defining how RPCs interact with each other, neighboring cell types and surrounding extracellular matrixes are critical to …

Magnetocaloric Effect Near Room Temperature In Quintenary And Sextenary Heusler Alloys, Benjamin D. White, R. I. Barabash, O. M. Barabash, I. Jeon, M. B. Maple

All Faculty Scholarship for the College of the Sciences

An inverse magnetocaloric effect is studied in Ni₂Mn_1+xX_1-x-type Heusler alloys. Principally known for their shape-memory properties, these alloys also exhibit significant entropy and temperature changes (ΔS and ΔT_Ad, respectively) under adiabatic conditions when a modest magnetic field is applied. We investigated the impact on magnetocaloric properties of introducing substantial chemical disorder on the X-site (X = Si, Ga, In), of replacing Ni with nonmagnetic Ag, and of replacing a small amount of Mn with Gd. While a reduction in ΔS is observed in the first two cases, we observe a significant enhancement …

Daily Eastern News: October 22, 2019, Eastern Illinois University

October

No abstract provided.

The Current Volume 30 : Issue 9, Nova Southeastern University

Student Newspapers

No abstract provided.

Center For Integration Of Science And Industry - Response To Ostp Bioeconomy Rfi, Fred D. Ledley

Natural & Applied Sciences Faculty Publications

RESPONSE TO: AGENCY: Office of Science and Technology Policy (OSTP). ACTION: Notice of request for information (RFI) for Bioeconomy Federal Register /Vol. 84, No. 175 /Tuesday, September 10, 2019 /Notices, page 47561 Transmitted electronically to [email protected]

What specific actions could the U.S. Government take to reinforce a values-based ecosystem that will guide the transformation and expansion of the U.S. Bioeconomy, in both the shortand long-term?

This response addresses specific actions the U.S. Government could take to ensure sustainable funding for the basic research that provides the foundation for the U.S. Bioeconomy. Empirical evidence demonstrates that a mature body of basic …

Purification Of Tag-Free Chlamydia Trachomatis Scc4 For Structural Studies Using Sarkosyl-Assisted On-Column Complex Dissociation, Thilini O. Ukwaththage, Octavia Y. Goodwin, Abigael C. Songok, Alexa M. Tafaro, Li Shen, Megan A. Macnaughtan

Faculty Publications

Copyright © 2019 American Chemical Society. Chlamydia trachomatis is an obligate intracellular bacterial pathogen that causes the most common sexually transmitted bacterial disease in the world. The bacterium has a unique biphasic developmental cycle with a type III secretion system (T3SS) to invade host cells. Scc4 is a class I T3SS chaperone forming a heterodimer complex with Scc1 to chaperone the essential virulence effector, CopN. Scc4 also functions as an RNA polymerase binding protein to regulate σ66-dependent transcription. Aggregation and low solubility of 6X-histidine-tagged Scc4 and the insolubility of 6X-histidine and FLAG-tagged Scc1 expressed in Escherichia coli have hindered the …

A Global Atlas Of The Environmental Risk Of Marinas On Water Quality, P Valdor, A Gomez, J Juanes, C Kerléguer, Et Al

School of Biological and Marine Sciences

Estimating the potential environmental risks of worldwide coastal recreational navigation on water quality is an important step towards designing a sustainable global market. This study proposes the creation of a global atlas of the environmental risk of marinas on water quality by applying the Marina Environmental Risk Assessment (MERA) procedure. Calculations integrate three main risk factors: Pressure, State and Response. Applying the MERA approach to 105 globally distributed marinas has confirmed the utility, versatility and adaptability of this procedure as a novel tool to compare the environmental risks within and among regions (i.e. for area-based management), to identify the world's …

The Patriot Talon (October 22, 2019), University Of Texas At Tyler

The Patriot Talon/The Patriot

The official newspaper for the University of Texas at Tyler before it was changed back to the UT Tyler Patriot. Articles in this issue include:Lakes lack spook factor, thrive in gnat herds. What's really in the Upper and Lower Harvey lake?; Annual safety report review: high fires, low crime; The future of hammocking on campus hangs in the balance; UT Tyler gets its own published YA student author; What's that song Riter Tower is playing?; On-campus jobs for international students: a benefit or a limitation?; UT Tyler's class on how not to kill a mockingbird; Trans Goose: A new representation; …

Phenylethynyl-Substituted Benzenes And Heterocycles For The Treatment Of Cancer, David S. Watt, Chunming Liu, Vitaliy M. Sviripa, Wen Zhang, Markos Leggas

Molecular and Cellular Biochemistry Faculty Patents

Halogenated phenylethynyl-substituted heterocycles that possess either an N-alkylamino or N,N-dialkylamino group attached to the heterocycle or halogenated phenylethynyl-substituted benzenes that a nitrogen-containing heterocycle attached to the benzene inhibit the proliferation cancer cells and are useful antineoplastic agents.

Choice Of Conditioning Regimens For Bone Marrow Transplantation In Severe Aplastic Anemia., Nelli Bejanyan, Soyoung Kim, Kyle M. Hebert, Natasha Kekre, Hisham Abdel-Azim, Ibrahim A. Ahmed, Mahmoud Aljurf, Sherif M. Badawy, Amer Beitinjaneh, Jaap Jan Boelens, Miguel Angel Diaz, Christopher C. Dvorak, Shahinaz Gadalla, James Gajewski, Robert Peter Gale, Siddhartha Ganguly, Andrew R. Gennery, Biju George, Usama Gergis, David Gómez-Almaguer, Marta Gonzalez Vicent, Hasan Hashem, Rammurti T. Kamble, Kimberly A. Kasow, Hillard M. Lazarus, Vikram Mathews, Paul J. Orchard, Michael Pulsipher, Olle Ringden, Kirk Schultz, Pierre Teira, Ann E. Woolfrey, Blachy Dávila Saldaña, Bipin Savani, Jacek Winiarski, Jean Yared, Daniel J. Weisdorf, Joseph H. Antin, Mary Eapen

Manuscripts, Articles, Book Chapters and Other Papers

Allogeneic bone marrow transplantation (BMT) is curative therapy for the treatment of patients with severe aplastic anemia (SAA). However, several conditioning regimens can be used for BMT. We evaluated transplant conditioning regimens for BMT in SAA after HLA-matched sibling and unrelated donor BMT. For recipients of HLA-matched sibling donor transplantation (n = 955), fludarabine (Flu)/cyclophosphamide (Cy)/antithymocyte globulin (ATG) or Cy/ATG led to the best survival. The 5-year probabilities of survival with Flu/Cy/ATG, Cy/ATG, Cy ± Flu, and busulfan/Cy were 91%, 91%, 80%, and 84%, respectively (P = .001). For recipients of 8/8 and 7/8 HLA allele-matched unrelated donor transplantation (n …

Summer 2019: Carpe Diem: Student Translates St. Norbert Sermon From Latin, St. Norbert College

St. Norbert College Magazine 2019-2023

Elle Maricque ’20 thought translating a 12th-century sermon attributed to St. Norbert sounded “super cool.” She says, “I like the beauties of life as well, and I think Latin is that.”

Colorado Oil And Gas Conservation Commission V. Martinez, Joseph Frydenlund

Denver Law Review Forum

No abstract provided.

Sub-Nanomolar Sensitive Gznp3 Reveals Trpml1-Mediated Neuronal Zn2+ Signals, Taylor F. Minckley, Chen Zhang, Dylan H. Fudge, Anna M. Dischler, Kate D. Lejeune, Haoxing Xu, Yan Qin

Biological Sciences: Faculty Scholarship

Although numerous fluorescent Zn2+ sensors have been reported, it is unclear whether and how Zn2+ can be released from the intracellular compartments into the cytosol due to a lack of probes that can detect physiological dynamics of cytosolic Zn2+. Here, we create a genetically encoded sensor, GZnP3, which demonstrates unprecedented sensitivity for Zn2+ at sub-nanomolar concentrations. Using GZnP3 as well as GZnP3-derived vesicular targeted probes, we provide the first direct evidence that Zn2+ can be released from endolysosomal vesicles to the cytosol in primary hippocampal neurons through the TRPML1 channel. Such TRPML1-mediated Zn2+ signals are distinct from Ca2+ in that …

A Modern Army Reserve For A Multi-Domain World: Structural Realities And Untapped Potential, Lewis G. Irwin Major General

Books, Monographs & Collaborative Studies

Since its inception in 1908, the US Army Reserve has made important, diverse, and cost-effective contributions to our nation while demonstrating the ability to adapt to meet emerging requirements. The emerging complex threats in today’s strategic and operational environments require the Army Reserve to adapt again.

Metabolic Modeling Elucidates The Transactions In The Rumen Microbiome And The Shifts Upon Virome Interactions, Mohammad Mazharul Islam, Samodha C. Fernando, Rajib Saha

Department of Chemical and Biomolecular Engineering: Faculty Publications

The complex microbial ecosystem within the bovine rumen plays a crucial role in host nutrition, health, and environmental impact. However, little is known about the interactions between the functional entities within the system, which dictates the community structure and functional dynamics and host physiology. With the advancements in high-throughput sequencing and mathematical modeling, in silico genome-scale metabolic analysis promises to expand our understanding of the metabolic interplay in the community. In an attempt to understand the interactions between microbial species and the phages inside rumen, a genome-scale metabolic modeling approach was utilized by using key members in the rumen microbiome …

Testing Protocols For Surveying Captive Limulus Polyphemus Microbiomes, Fabian Leija, Sean A. Neiswenter Dr.

LSAMP Poster Presentations

Limulus polyphemus, the Atlantic horseshoe crab, is a marine arthropod that primarily resides in the shallow intertidal zone of brackish water, water where high salinity seawater meets fresh water. The ecological niche that horseshoe crabs reside in makes them an ideal animal to be placed in an aquarium touch-tank, only needing a shallow pool of water to live comfortably as well as having a tough chitin carapace that won’t be easily damaged by visitors touching them. However, the implications of these human-animal interactions are severely unexplored with limited research being conducted regarding touch-tanks. In contrast, the consequences and hygienic practices …

Stacked Core-Shell & Self-Supported Nanorod Array Electrocatalysts For Pem Fuel Cells, Fatma Merve Yurtsever

Theses and Dissertations

Polymer electrolyte membrane fuel cell (PEMFC) is one of the most attractive technologies for clean, renewable energy in the twenty-first century. It has many advantages in terms of zero carbon emission, quiet operation mode, high power density, higher efficiency than Carnot engines, and it requires less warm-up & fast start-up time. However, oxygen reduction reaction (ORR) activity and stability are still significant issues for the next generation PEMFCs to increase its usage. In this study, we developed a new design of stacked core-shell nanorod array and self-supported composition graded Pt:Ni nanorod array electrocatalyst to improve ORR kinetics and catalyst stability. …

Samarium-Activated La2hf2o7 Nanoparticles As Multifunctional Phosphors, Santosh K. Gupta, Maya Abdou, Jose P. Zuniga, Alexander A. Puretzky, Yuanbing Mao

School of Integrative Biological & Chemical Sciences (Formerly Dept. of Chemistry)

Recent developments in the field of designing novel nanostructures with various functionalities have pushed the scientific world to design and develop high-quality nanomaterials with multifunctional applications. Here, we propose a new kind of doped metal oxide pyrochlore nanostructure for solid-state phosphor, X-ray scintillator, and optical thermometry. The developed samarium-activated La2Hf2O7 (LHOS) nanoparticles (NPs) emit a narrow and stable red emission with lower color temperature and adequate critical distance under near-UV and X-ray excitations. When the LHOS NPs are exposed to an energetic X-ray beam, the Sm3+ ions situated at the symmetric environment get excited along with those located at the …

Characterization Of Resistance To A Potent D-Peptide Hiv Entry Inhibitor., Amanda R Smith, Matthew T Weinstock, Amanda E Siglin, Frank G Whitby, J Nicholas Francis, Christopher P Hill, Debra M Eckert, Michael J Root, Michael S Kay

Department of Biochemistry and Molecular Biology Faculty Papers

BACKGROUND: PIE12-trimer is a highly potent D-peptide HIV-1 entry inhibitor that broadly targets group M isolates. It specifically binds the three identical conserved hydrophobic pockets at the base of the gp41 N-trimer with sub-femtomolar affinity. This extremely high affinity for the transiently exposed gp41 trimer provides a reserve of binding energy (resistance capacitor) to prevent the viral resistance pathway of stepwise accumulation of modest affinity-disrupting mutations. Such modest mutations would not affect PIE12-trimer potency and therefore not confer a selective advantage. Viral passaging in the presence of escalating PIE12-trimer concentrations ultimately selected for PIE12-trimer resistant populations, but required an extremely …

Perturbed Mitochondria-Er Contacts In Live Neurons That Model The Amyloid Pathology Of Alzheimer's Disease., Pamela V. Martino Adami, Zuzana Nichtova, David B. Weaver, Adam Bartok Dr., Thomas Wisniewski, Drew R. Jones, Sonia Do Carmo, Eduardo M. Castaño, A. Claudio Cuello, György Hajnóczky, Laura Morelli

Department of Pathology, Anatomy, and Cell Biology Faculty Papers

The use of fixed fibroblasts from familial and sporadic Alzheimer's disease patients has previously indicated an upregulation of mitochondria-ER contacts (MERCs) as a hallmark of Alzheimer's disease. Despite its potential significance, the relevance of these results is limited because they were not extended to live neurons. Here we performed a dynamic in vivo analysis of MERCs in hippocampal neurons from McGill-R-Thy1-APP transgenic rats, a model of Alzheimer's disease-like amyloid pathology. Live FRET imaging of neurons from transgenic rats revealed perturbed 'lipid-MERCs' (gap width <10 nm), while 'Ca2+-MERCs' (10-20 nm gap width) were unchanged. In situ TEM showed no significant differences in the lipid-MERCs:total MERCs or lipid-MERCs:mitochondria ratios; however, the average length of lipid-MERCs was significantly decreased in neurons from transgenic rats as compared to controls. In accordance with FRET results, untargeted lipidomics showed significant decreases in levels of 12 lipids and bioenergetic analysis revealed respiratory dysfunction of mitochondria from transgenic rats. Thus, our results reveal changes in MERC structures coupled with impaired mitochondrial functions in Alzheimer's disease-related neurons.This article has an associated First Person interview with the first author of the paper.

Math And Science Post-Basic Education School Teachers’ Use Of As-Sessment For Learning And Assessment Of Learning Practices In Oman, Mahmoud F. Alquraan, Ahmed A. Al-Shaqsi

Journal of Educational and Psychological Studies

The present study aimed at investigating math and science post-basic education school teachers’ use of Assessment for Learning (AfL) and Assessment of Learning (AoL) Practices in Oman from teachers’ points of view and as perceived by their educational supervisors. To achieve the objectives of this study, a 31-item of Likert type questionnaire was used. The questionnaire was divided into two subscales. The first subscale contains 12 AoL practices while the second one contains 19 AfL practices. The questionnaire was distributed to 288 math, biology, physics, and chemistry teachers and to 78 math and science educational supervisors. The results show that …

Omani School Students’ Attitudes Toward Agriculture: Investigating The Role Of Gender And Geographical Regions, Abdullah Ambusaidi, Mohammed Al-Saidi

Journal of Educational and Psychological Studies

A 24-item questionnaire was designed to collect specific data in order to determine Omani students’ attitudes toward agriculture and, specifically, whether or not these attitudes differ according to gender and the geographical regions where students reside. A survey research method based on the use of a questionnaire was employed. The questionnaire items were divided into four domains: participants’ general knowledge about agriculture, their personal interest about agriculture, the role of government in supporting agriculture, and the role of agriculture in food security. The questionnaire was administered to 394 randomly selected Grade 10 students. Participants consisted of 189 male students and …

Interpreting Non-Amish Perceptions Of The Old Order Amish Using Cultural Relativism And Human Rights Frameworks, Kristin Park

Journal of Amish and Plain Anabaptist Studies

Relatively little is known about how ordinary non-Amish citizens interact with and perceive their Old Order Amish neighbors. This study used interpretive and semi-inductive approaches with in-depth interviews to describe and analyze interactions and perceptions of non-Amish research participants. Sixteen subjects were identified from purposive, snowball and theoretical sampling in a region near a sizeable, very tradition-minded Old Order settlement. All participants engaged in secondary relationships, while several individuals had intimate and enduring relationships with a small number of Amish individuals and families. While most participants perceived their Amish acquaintances and friends as honest, hard-working, caring and community-minded, some expressed …

Use Of Old Order Anabaptist-Produced Publications To Develop An Injury Surveillance System For Old Order Populations, Paul Jones, William Field, Donald Kraybill, Stephen Scott

Journal of Amish and Plain Anabaptist Studies

To achieve a clearer picture of injuries within Old Order Anabaptist communities, Purdue University’s Agricultural Safety and Health Program collaborated with the Young Center for Anabaptist and Pietist Studies at Elizabethtown College to conduct a pilot study on this topic. The team developed an injury surveillance system based not on traditional injury data sources and instruments but on data provided in Old Order-produced publications, specifically The Budget, Die Botschaft, and The Diary. While traditional surveillance methods have generally yielded injury data on less than 30 Old Order cases per year, the Old Order Injury Database, developed through the Purdue/Young Center …

Description Of The Adult Male Of Euscorpius Feti Tropea, 2013 (Scorpiones: Euscorpiidae), With Notes On Cave Ecology Of This Species, Gioele Tropea, Roman Ozimec

Euscorpius

The adult male of Euscorpius feti Tropea, 2013 (Euscorpiidae) is described for the first time. A large series (45 specimens including the type material) has been studied, most of the material previously unpublished. E. feti has been found in as many as 17 caves in Croatia and Bosnia-Herzegovina, including the Adriatic islands, which makes it the most common Euscorpius species so far found in caves. Ecological notes on this species are presented.

Growing Local: The Role Of Urban Gardening In Fostering Food Security, Sustainability, And Community, Franklin Wagner, Lindsey Payne

Purdue Journal of Service-Learning and International Engagement

The downtown center of Lafayette, Indiana is situated in a food desert where access to healthy, nutritious food can be limited. Urban gardens are an effective way to increase access to healthy alternatives while also providing a number of benefits to the surrounding area, including opportunities for community growth, education, and physical activity. In summer 2016, researchers from Purdue University collaborated with Lafayette’s GrowLocal Urban Gardens Network (GrowLocal) to perform a baseline analysis of the current community gardening initiatives, and explore the possibilities for expansion, development, and future community involvement through urban gardening.

Both qualitative and quantitative data collection methods …