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2019

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Team Member Hormone Profiles And Group Cohesion, David Webster Jan 2019

Team Member Hormone Profiles And Group Cohesion, David Webster

Theses and Dissertations (Comprehensive)

Group cohesion in sport is associated with many positive outcomes for the team as a whole, as well as for the individuals. Hence, it is important to understand the antecedents of cohesion in various contexts, including sport. One antecedent that has yet to be examined in a sports context pertains to biological factors; specifically, the interaction of testosterone and cortisol levels. The dual-hormone hypothesis posits that testosterone levels are associated with status attainment for both individuals and groups, but only amongst those with low cortisol levels. Based on previous literature, a high testosterone-low cortisol hormonal profile should be associated with …

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Competition Or Facilitation: Examination Of Interactions Between Endangered Sida Hermaphrodita And Invasive Phragmites Australis, Samantha N. Mulholland Jan 2019

Competition Or Facilitation: Examination Of Interactions Between Endangered Sida Hermaphrodita And Invasive Phragmites Australis, Samantha N. Mulholland

Theses and Dissertations (Comprehensive)

Virginia Mallow (Sida hermaphrodita) is a perennial herb of the Malvaceae family that is native to riparian habitats in northeastern North America. Throughout most of its geographical distribution however, it is considered threatened and only two populations are known from Canada. The biology and ecology of S. hermaphrodita are still poorly understood and although few studies have been performed to determine the factors that contribute to the species rarity, it is considered threatened potentially due to the loss of habitat caused by exotic European Common reed (Phragmites australis subsp. australis) invasion. Allelopathic and phytotoxic conditioning of …

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Investigating The Antiviral Effects Of Vig-3 From Rainbow Trout, Shanee Herrington-Krause Jan 2019

Investigating The Antiviral Effects Of Vig-3 From Rainbow Trout, Shanee Herrington-Krause

Theses and Dissertations (Comprehensive)

Rainbow trout is the most farmed fish in Ontario, and thus is economically important to the province. Despite this, there is a lack of understanding regarding fish innate immunity, specifically with regards to interferon-stimulated genes (ISGs) and their antiviral effector functions. ISGs are the workhorses of the innate antiviral response, operating together to limit each step of virus replication. The Viral Hemorrhagic Septicemia Virus (VHSV) induced gene (Vig)-3 is a newly identified ISG within many fish species and is homologous to ISG-15 in mammals. It is a small ubiquitin-like protein inducible by type I interferon (IFN-I), and is suggested to …

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Effects Of The Feeds Containing Hazelnut Meal As Plant Protein Source On Growth Performance And Body Composition Of Siberian Sturgeon (Acipenser Baeri) And Economic Profitability Value, Huri̇ye Ariman Karabulut, İlker Zeki̇ Kurtoğlu, Yunus Emre Kirtan Jan 2019

Effects Of The Feeds Containing Hazelnut Meal As Plant Protein Source On Growth Performance And Body Composition Of Siberian Sturgeon (Acipenser Baeri) And Economic Profitability Value, Huri̇ye Ariman Karabulut, İlker Zeki̇ Kurtoğlu, Yunus Emre Kirtan

Turkish Journal of Veterinary & Animal Sciences

In this study, the effects of feeding with the diets containing hazelnut meal (HM) at different levels (0%, 15%, 30%, and 45%) on the growth performance and body composition of Siberian sturgeon were investigated. The study was carried out for 90 days with 3 replicates (n = 15; 283.1 ± 6.52 g fish weight). The highest weight gain (180.62 ± 2.84%) was observed in the control group followed by 15%, 30%, and 45% HM. When the groups were evaluated in terms of SGR, FCR, and PER, the control group was observed to have the best performance. The control group and …

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Methods Of Diagnosis And Treatment Of Postpartum Uterine Infection Adopted By Algerian Veterinarians, Hamza Rahab, Alessandro Ricci, Ahmed Kasseh-Laouar, Christian Hanzen Jan 2019

Methods Of Diagnosis And Treatment Of Postpartum Uterine Infection Adopted By Algerian Veterinarians, Hamza Rahab, Alessandro Ricci, Ahmed Kasseh-Laouar, Christian Hanzen

Turkish Journal of Veterinary & Animal Sciences

The present study aimed to monitor the practices of Algerian veterinarians in the diagnosis and treatment of puerperal metritis (PM) and clinical endometritis (CE) in cattle. For this purpose, a questionnaire was established and distributed to collect the information concerning veterinarian profiles and practices related to the diagnosis and treatment of PM and CE. The results showed that examinations of the uterus (rectal palpation), vaginal discharge, and rectal temperature were the most practiced methods for PM (71%, 68%, and 83%, respectively) and CE (86%, 60%, and 65%, respectively) diagnosis. Tetracycline was the antibiotic of choice for intrauterine treatment of PM …

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Accumulation And Histological Transformation In The Gills, Liver, Muscles, And Skin In Oreochromis Niloticus Induced By Mercury, Khalid Abdullah Al-Ghanim, Zubair Ahmad, Hmoud Fares Alkahem Al-Balawi, Fahad Al-Misned, Shahid Mahboob, El Amin Mohammad Suliman Jan 2019

Accumulation And Histological Transformation In The Gills, Liver, Muscles, And Skin In Oreochromis Niloticus Induced By Mercury, Khalid Abdullah Al-Ghanim, Zubair Ahmad, Hmoud Fares Alkahem Al-Balawi, Fahad Al-Misned, Shahid Mahboob, El Amin Mohammad Suliman

Turkish Journal of Veterinary & Animal Sciences

Specimens of Oreochromis niloticus (One control and 3 experimental groups) were fed diets mixed with different doses of mercury (control group = free of mercury; group 1 = 500 mg/kg; group 2 = 750 mg/kg, and group 3 = 1000 mg/kg) for 60 days in order to study its accumulation and histopathological alterations in the liver, gills, skeletal muscles, and skin. The results obtained revealed that mercury accumulation was significantly (P < 0.05) high in the liver and gills compared to the muscles and skin. The order of accumulation in these organs revealed to be liver > gills > muscles > skin. The fish fed various doses of mercury also showed histological alterations in these organs. Epithelial lifting and epithelial hypertrophy were seen in the gills of the …

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Evaluation Of Milk Glutathione Peroxidase And Superoxide Dismutase Levels In Subclinical Mastitis In Damascus Goats, İsfendi̇yar Darbaz, Seçki̇n Salar, Serkan Sayiner, İdi̇l Baştan, Osman Ergene, Ayhan Baştan Jan 2019

Evaluation Of Milk Glutathione Peroxidase And Superoxide Dismutase Levels In Subclinical Mastitis In Damascus Goats, İsfendi̇yar Darbaz, Seçki̇n Salar, Serkan Sayiner, İdi̇l Baştan, Osman Ergene, Ayhan Baştan

Turkish Journal of Veterinary & Animal Sciences

The aim of this study was to evaluate milk glutathione peroxidase (GPx) and superoxide dismutase (SOD) levels in Damascus goats with subclinical mastitis. According to the somatic cell counts (SCCs), 193 Damascus goats included in the study were divided into healthy (n = 75; SCC 0.05). In summary, a significant increase in GPx and decrease in SOD levels, respectively, were determined in goat milk samples with subclinical mastitis, and these changing trends were correlated with milk SCCs. However, age, parity, and number of offspring were not associated with these changing patterns.

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Proliferation Effects Of Phenylboronic Acid And Boric Acid On Canine Peripheral Blood Mononuclear Cells, Uçkun Sai̇t Uçan, Zafer Sayin Jan 2019

Proliferation Effects Of Phenylboronic Acid And Boric Acid On Canine Peripheral Blood Mononuclear Cells, Uçkun Sai̇t Uçan, Zafer Sayin

Turkish Journal of Veterinary & Animal Sciences

The effects of phenylboronic acid (PBA) and boric acid (BA) on the proliferation of canine peripheral blood mononuclear cells (PBMCs) were investigated. Treatment of PBMCs from mixed breed dogs with PBA or BA (0.05 µg/mL) alone elicited blastogenic responses of 0.478 ± 0.438 and 0.499 ± 0.366, respectively. We observed an additive effect on proliferation when purebred Kangal PBMCs were cultured in a combination of BA (0.001 µg/mL) and the mitogenic lectin concanavalin A (1 µg/mL). However, the effects were not statistically significant. We detected varied IL-2 and IL-4 secretion in response to stimulation with boron-containing compounds. Our findings suggest …

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Effects Of The Inclusion Of Detoxified Argan Press Cake In The Diet Of Dairy Goats On Milk Production And Milk Quality, Nazha Lakram, Sana Moutik, Ikram Mercha, El Haj El Maadoudi, Rachid Kabbour, Ahmed Douaik, Abdelmajid Zouahri, Abdelah El Housni, Mariam Naciri Jan 2019

Effects Of The Inclusion Of Detoxified Argan Press Cake In The Diet Of Dairy Goats On Milk Production And Milk Quality, Nazha Lakram, Sana Moutik, Ikram Mercha, El Haj El Maadoudi, Rachid Kabbour, Ahmed Douaik, Abdelmajid Zouahri, Abdelah El Housni, Mariam Naciri

Turkish Journal of Veterinary & Animal Sciences

This study was carried out to assess the effect of the incorporation of detoxified argan press cake on milk yield, physicochemical composition, and microbial quality of raw Alpine goat milk produced in the Meskala-Essaouira region of southwestern Morocco. The detoxification method, adopted for the removal of saponin present in the argan press cake, succeeded in reducing these antinutrients from 4.56 to 0.4 mg/g, allowing it to be used as livestock feed. The average of milk production increased by 24% for the detoxified argan press cake (DAPC) group compared to the argan press cake and local diet groups. The diets and …

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Genetic Analysis Of Iranian Mycoplasma Gallisepticum Isolates Using Gene-Targeted Sequencing Of Complete Pvpa Gene, Naghmeh Kabiri, Mohsen Bashashati, Mehdi Vasfi Marandi, Mansour Banani, Fereshteh Sabouri Jan 2019

Genetic Analysis Of Iranian Mycoplasma Gallisepticum Isolates Using Gene-Targeted Sequencing Of Complete Pvpa Gene, Naghmeh Kabiri, Mohsen Bashashati, Mehdi Vasfi Marandi, Mansour Banani, Fereshteh Sabouri

Turkish Journal of Veterinary & Animal Sciences

This study aims to evaluate Mycoplasma gallisepticum (MG) genetic diversity through the complete sequencing of the pvpA gene among six MG isolates present in industrial poultry from 2015 to 2016. The genetic comparison of these six isolates showed similarities of over 94% and 92% in terms of nucleotide and amino acid sequences, respectively. The size of the PvpA protein in the studied isolates included three different sizes with 361, 364, and 366 amino acids. The carboxy-terminus of the studied PvpA proteins contained 11 tetrapeptides of P-R-P-M/Q/N motifs with truncation in the proline-rich region. Based on the BLAST analysis, the pvpA …

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Isolation And Molecular Characterization Of Salmonella Enterica And Escherichia Coli From Poultry Samples, Ayli̇n Cesur, Saci̇de Özlem Ulutaş, Yeşi̇m Soyer Jan 2019

Isolation And Molecular Characterization Of Salmonella Enterica And Escherichia Coli From Poultry Samples, Ayli̇n Cesur, Saci̇de Özlem Ulutaş, Yeşi̇m Soyer

Turkish Journal of Veterinary & Animal Sciences

Innumerable foodborne pathogens including Salmonella and Escherichia coli pose a serious threat to human health and food safety. As perishable foods, poultry products are considered one of the most common sources of foodborne pathogens including Salmonella and E. coli due to transmission of drug resistance, dissemination of organisms, and cross-contamination. In our study, phenotypic and genotypic characterizations of Salmonella enterica and E. coli isolated from packaged raw chicken products were carried out. Samples belonging to different commercial brands were collected in Ankara in 2015. Among 15 out of 19 Salmonella enterica subsp. enterica strains isolated from different and/or same poultry …

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Doctoral Engineering Grant Writing Experience To Prepare Future Professionals And Faculty, Katherine Smith, Nathapon Siangchokyoo, Erika Gamarra, Ashish Tamhane, Anthony W. Dean Jan 2019

Doctoral Engineering Grant Writing Experience To Prepare Future Professionals And Faculty, Katherine Smith, Nathapon Siangchokyoo, Erika Gamarra, Ashish Tamhane, Anthony W. Dean

Engineering Technology Faculty Publications

While there have been many efforts to broaden opportunities for all STEM students by engaging in interdisciplinary endeavors and education focusing on professional development, there are particular problems facing students pursuing doctoral degrees in engineering disciplines. Doctoral programs of the future need to become better equipped to prepare students for future careers as engineering professionals or faculty. It has been noted recently that many doctoral degree recipients are turning to jobs outside of academia but increases in undergraduate enrollment and the average age of the professoriate indicate an increase in demand for new faculty. Both future faculty and professionals can …

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Drug Repositioning Based On Bounded Nuclear Norm Regularization, Mengyun Yang, Huimin Lao, Yaohang Li, Jianxin Wang Jan 2019

Drug Repositioning Based On Bounded Nuclear Norm Regularization, Mengyun Yang, Huimin Lao, Yaohang Li, Jianxin Wang

Computer Science Faculty Publications

Motivation: Computational drug repositioning is a cost-effective strategy to identify novel indications for existing drugs. Drug repositioning is often modeled as a recommendation system problem. Taking advantage of the known drug–disease associations, the objective of the recommendation system is to identify new treatments by filling out the unknown entries in the drug–disease association matrix, which is known as matrix completion. Underpinned by the fact that common molecular pathways contribute to many different diseases, the recommendation system assumes that the underlying latent factors determining drug–disease associations are highly correlated. In other words, the drug–disease matrix to be completed is low-rank. Accordingly, …

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Clinical Big Data And Deep Learning: Applications, Challenges, And Future Outlooks, Ying Yu, Liangliang Liu, Yaohang Li, Jianxin Wang Jan 2019

Clinical Big Data And Deep Learning: Applications, Challenges, And Future Outlooks, Ying Yu, Liangliang Liu, Yaohang Li, Jianxin Wang

Computer Science Faculty Publications

The explosion of digital healthcare data has led to a surge of data-driven medical research based on machine learning. In recent years, as a powerful technique for big data, deep learning has gained a central position in machine learning circles for its great advantages in feature representation and pattern recognition. This article presents a comprehensive overview of studies that employ deep learning methods to deal with clinical data. Firstly, based on the analysis of the characteristics of clinical data, various types of clinical data (e.g., medical images, clinical notes, lab results, vital signs and demographic informatics) are discussed and details …

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Microborings As Indication Of Cryptic Life Modes In The Foraminifer Orbitoides:Maastrichtian Sediments Of The Haymana And Nallıhan Districts (Ankara, Turkey), Muhi̇tti̇n Görmüş, Huri̇ye Demi̇rcan, Yusuf Kağan Kadioğlu, Fuzuli̇ Yağmurlu, Muhammed Sami̇ Us Jan 2019

Microborings As Indication Of Cryptic Life Modes In The Foraminifer Orbitoides:Maastrichtian Sediments Of The Haymana And Nallıhan Districts (Ankara, Turkey), Muhi̇tti̇n Görmüş, Huri̇ye Demi̇rcan, Yusuf Kağan Kadioğlu, Fuzuli̇ Yağmurlu, Muhammed Sami̇ Us

Turkish Journal of Earth Sciences

Widespread Maastrichtian siliciclastics and carbonates cropping out in the Haymana (S Ankara) and Nallıhan (NW Ankara) districts in the northwest and central Anatolia basins include rich Orbitoides occurrences. Microborings in the Orbitoides tests are interesting to notify. In this study, the details of their morphologic structures were investigated. Microborings were analyzed in more than 650 equatorial thin sections of the Orbitoides tests and 100 hard rock thin sections. The abundance of microborings increases in the siliciclastics towards the Cretaceous/Palaeogene boundary (K/Pg). They were identified as Maeandropolydora osmaneliensis Nielsen and Görmüş, Maeandropolydora isp. Curvichnus semorbis Nielsen, Oichnus simplex Bromley, Oichnus isp. …

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Response Of Breast Cancer Cells To Ifnî±-2b In 2d And 3d Cell Cultures, Tetiana Herheliuk, Olena Perepelytsina, Andrij Ugnivenko, Lyudmila Ostapchenko, Mychailo Sydorenko Jan 2019

Response Of Breast Cancer Cells To Ifnî±-2b In 2d And 3d Cell Cultures, Tetiana Herheliuk, Olena Perepelytsina, Andrij Ugnivenko, Lyudmila Ostapchenko, Mychailo Sydorenko

Turkish Journal of Biology

The effect of IFNα-2b on the migration, proliferation, and expression of epithelial and mesenchymal markers of MCF-7 tumor adenocarcinoma cells in 2D and 3D cell cultures was examined. A significant cytostatic effect of IFNα-2b on the tumor population was detected. It was found that changes in the expression of epithelial (CKs and EpCAM) and mesenchymal markers were caused by changing the growth type of the tumor population. IFNα-2b inhibited migration of tumor cells to the suspension fraction and promoted an increase in expression of CK and EpCAM in 2D and 3D cell cultures, but only in the 3D culture was …

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Transcriptome Analysis Reveals Differentially Expressed Genes Between Human Primary Bone Marrow Mesenchymal Stem Cells And Human Primary Dermal Fibroblasts, Eki̇m Z. Taşkiran, Beren Karaosmanoğlu Jan 2019

Transcriptome Analysis Reveals Differentially Expressed Genes Between Human Primary Bone Marrow Mesenchymal Stem Cells And Human Primary Dermal Fibroblasts, Eki̇m Z. Taşkiran, Beren Karaosmanoğlu

Turkish Journal of Biology

Stromal cells have been widely used in biomedical research and disease modeling studies in vitro. The most commonly used types of stromal cells are mesenchymal stem cells and fibroblasts. Their cellular phenotypes and differentiation capabilities are quite similar and there are no specific distinction criteria. In order to identify transcriptomic differences between these 2 cell types, we performed next-generation RNA sequencing. Using the global gene expression profile and pathway analysis, we showed that human primary bone marrow mesenchymal stem cells and human primary dermal fibroblasts have different molecular signatures. We also identified critical transcription factors that are differentially expressed between …

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Genome And Metabolome Mining Of Marine Obligate Salinispora Strains To Discover New Natural Products, Süleyman Özakin, Ebru İnce Bostanci Jan 2019

Genome And Metabolome Mining Of Marine Obligate Salinispora Strains To Discover New Natural Products, Süleyman Özakin, Ebru İnce Bostanci

Turkish Journal of Biology

Marine microorganisms are receiving more attention as a promising potential source of new natural products. In the present study, we performed genomic and metabolomic analyses to explore the metabolic potential of the obligate marine actinomycete genus Salinispora. The genomes of thirty Salinispora strains were prospected in search of biosynthetic gene clusters including polyketide synthase (PKS), nonribosomal peptide synthetase (NPRS), terpene, indole, lantibiotics, and siderophores. We determined considerable diversity of natural product biosynthetic gene clusters in their genome. There were a total of 1428 putative gene clusters involved in the biosynthesis of various bioactive natural products. Furthermore, 1509 ketosynthase (KS) and …

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Effects Of Notch Signalling On The Expression Of Sema3c, Hmga2, Cxcl14, Cxcr7, And Ccl20 In Breast Cancer, Cansu Küçükköse, Özden Yalçin Özuysal Jan 2019

Effects Of Notch Signalling On The Expression Of Sema3c, Hmga2, Cxcl14, Cxcr7, And Ccl20 In Breast Cancer, Cansu Küçükköse, Özden Yalçin Özuysal

Turkish Journal of Biology

Metastasis is the main reason for death in breast cancer. Understanding the molecular players in metastasis is crucial for diagnostic and therapeutic purposes. Notch signalling plays an oncogenic role in breast tumorigenesis and is involved in metastasis. Downstream mediators of Notch signalling in prometastatic processes are not yet fully discovered. Here we aimed to investigate whether Notch signalling regulates the expression of SEMA3C, HMGA2, CXCL14, CXCR7, and CCL20, which are involved in prometastatic processes, in breast cell lines. To this end, expression of the selected genes was analysed following Notch activation by overexpression of the Notch1 intracellular domain in the …

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Cover And Contents Jan 2019

Cover And Contents

Turkish Journal of Biology

No abstract provided.

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Complete Genome Sequence Analysis Of A Lytic Shigella Flexneri Vb_Sfls-Isf001 Bacteriophage, Khashayar Shahin, Majid Bouzari, Ran Wang Jan 2019

Complete Genome Sequence Analysis Of A Lytic Shigella Flexneri Vb_Sfls-Isf001 Bacteriophage, Khashayar Shahin, Majid Bouzari, Ran Wang

Turkish Journal of Biology

Shigellosis is one of the most important acute enteric infections caused by different species of Shigella, such as Shigella flexneri. Despite the use of antibiotic therapy to reduce disease duration, this approach is becoming less effective due to the emergence of antibiotic resistance among Shigella spp. Bacteriophages have been introduced as an alternative for controlling shigellosis. However, the bacteriophages must be without any lysogenic or virulence factors, toxin coding, or antibiotic-resistant genes. In this study, the whole genome sequence of vB_SflS-ISF001, a virulent Siphoviridae bacteriophage specific for Shigella flexneri, was obtained, and a comparative genomic analysis was carried out to …

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Identification Of Bioactive Compounds From Fraxinus Angustifolia Extracts With Anti-Nadh Oxidase Activity Of Bovine Milk Xanthine Oxidoreductase, Nadjia Ahmane, Dina Atmani-Kilani, Nassima Chaher, Karima Ayouni, Meriem Rahmani-Berboucha, Gregory Da Costa, Nadjet Debbache-Benaida, Tristan Richard, Djebbar Atmani Jan 2019

Identification Of Bioactive Compounds From Fraxinus Angustifolia Extracts With Anti-Nadh Oxidase Activity Of Bovine Milk Xanthine Oxidoreductase, Nadjia Ahmane, Dina Atmani-Kilani, Nassima Chaher, Karima Ayouni, Meriem Rahmani-Berboucha, Gregory Da Costa, Nadjet Debbache-Benaida, Tristan Richard, Djebbar Atmani

Turkish Journal of Biology

Fraxinus angustifolia leaves and bark are used in traditional medicine against various inflammatory-related pathologies incumbent to reactive oxygen species (ROS) generation by the NADH oxidase activity of enzymes such as xanthine oxidoreductase (XOR). This study was designed to investigate the in vitro and in vivo inhibitory activities of this enzyme by Fraxinus angustifolia extracts. The leaf organic phase of ethyl acetate (LFA) and its bark aqueous counterpart (BFA) showed the strongest anti-NADH oxidase activity in vitro (IC50 = 38.51 and 42.04 μg mL-1, respectively). They consequently suppressed superoxide generation both enzymatically (53% and 19%, respectively) and nonenzymatically (34% and 19%, …

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Functional Characteristics Of Lactobacilli From Traditional Bulgarian Fermented Milk Products, Veronica Nemska, Petya Logar, Tanya Rasheva, Zdravka Sholeva, Nelly Georgieva, Svetla Danova Jan 2019

Functional Characteristics Of Lactobacilli From Traditional Bulgarian Fermented Milk Products, Veronica Nemska, Petya Logar, Tanya Rasheva, Zdravka Sholeva, Nelly Georgieva, Svetla Danova

Turkish Journal of Biology

After oral administration, probiotic lactobacilli meet a number of protection systems in the human body, such as exposure to gastric, pancreatic, and small intestinal juices. Overcoming these detrimental barriers allows living bacteria to adhere to the intestinal epithelium and permanently colonize the gastrointestinal tract (GIT), providing health benefits to the host. Based on this, the transit tolerance of 25 candidate probiotic lactobacilli from katak, yoghurt, and white-brined and yellow cheese to simulated bile and small intestinal juices of variable pH was investigated. To establish their resistance, in vitro model systems based on modified MRS media and a longer duration of …

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Cover And Contents Jan 2019

Cover And Contents

Turkish Journal of Agriculture and Forestry

No abstract provided.

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Comparison Of Maize Lines And Their Test Crosses According To Grain Yield And Somephysiological Properties, Eli̇f Özdemi̇r, Bayram Sade Jan 2019

Comparison Of Maize Lines And Their Test Crosses According To Grain Yield And Somephysiological Properties, Eli̇f Özdemi̇r, Bayram Sade

Turkish Journal of Agriculture and Forestry

This study evaluated 7 inbred lines of maize (Zea mays L.), 3 testers, and 21 hybrids produced using the line × tester mating design. The study was conducted in Konya, in The Central Anatolia Region of Turkey. CD (coefficient of determination) values were calculated to detect the effect of inbred lines on grain yield and other physiological properties of the test crosses. The mean values of all the parameters of the genotypes were evaluated using the Duncan?s multiple range test for grouping progenies and parent groups. The CD values between parent groups and progenies were statistically significant for photosynthetic efficiency …

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Examining The Involvement Of Slx5 In The Apoptotic Response To Chronic Activation Of The Spindle Assembly Checkpoint, Pinar Buket Atalay, Eli̇f Ergi̇n Çavuşoğlu, Öykü Aşci, Duygu Aygüneş Jan 2019

Examining The Involvement Of Slx5 In The Apoptotic Response To Chronic Activation Of The Spindle Assembly Checkpoint, Pinar Buket Atalay, Eli̇f Ergi̇n Çavuşoğlu, Öykü Aşci, Duygu Aygüneş

Turkish Journal of Biology

Microtubule-targeting agents represent one of the most successful groups of anticancer drugs used in cancer therapy today. These drugs induce a prolonged mitotic arrest through chronic spindle assembly checkpoint (SAC) activation. Apoptosis, an outcome of the prolonged mitotic arrest, is the main mechanism by which these anticancer drugs kill cancer cells. However, not much is known about the mechanism that directs chronic SAC activation to apoptosis among other possible outcomes. The aim of this study is to investigate whether Slx5, a sumo-targeted ubiquitin E3 ligase, is involved in directing chronic SAC activation to apoptosis. We show that chronic SAC activation …

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Design, Development, And Evaluation Of A Target Oriented Weed Control System Usingmachine Vision, Ömer Bariş Özlüoymak, Ali̇ Bolat, Ali̇ Bayat, Emi̇n Güzel Jan 2019

Design, Development, And Evaluation Of A Target Oriented Weed Control System Usingmachine Vision, Ömer Bariş Özlüoymak, Ali̇ Bolat, Ali̇ Bayat, Emi̇n Güzel

Turkish Journal of Agriculture and Forestry

The objective of the study was to develop and test an automatic machine vision-based spraying robot for the detection, tracking, and spraying of artificial weeds by using LabVIEW programming language. The greenness method was used to distinguish green objects in the image. A time-controlled spray nozzle was run according to the presence of an artificial weed and its coordinates. A mobile test bench was built and the spraying system with a webcam was operated at speeds of 0.42, 0.54, 0.66, 0.78, and 0.90 km h-1, so as to be able to see the performance of the system. The amount of …

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Precipitation And Characterization Of Caco3 Of Bacillus Amyloliquefaciens U17 Strain Producing Urease And Carbonic Anhydrase, Merve Tepe, Şevki̇ Arslan, Tamer Koralay, Nazi̇me Mercan Jan 2019

Precipitation And Characterization Of Caco3 Of Bacillus Amyloliquefaciens U17 Strain Producing Urease And Carbonic Anhydrase, Merve Tepe, Şevki̇ Arslan, Tamer Koralay, Nazi̇me Mercan

Turkish Journal of Biology

In the present study, the properties of calcium carbonate mineralization and urease and carbonic anhydrase activities of Bacillus amyloliquefaciens U17 isolated from calcareous soil of Denizli (Turkey) were analyzed. CaCO3 was produced in all growth phases. Strain U17 showed 0.615 ± 0.092 μmol/min/mg urease enzyme activity in calcium mineralization medium and 1.315 ± 0.021 μmol/min/mg urease enzyme activity in Luria-Bertani medium supplemented with urea, whereas it showed 36.03 ± 5.48 nmol/min/ mg carbonic anhydrase enzyme activity in CaCO3 precipitation medium and 28.82 ± 3.31 nmol/min/mg carbonic anhydrase enzyme activity in Luria-Bertani medium supplemented with urea. The urease B protein expression …

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Effects Of B2o3 (Boron Trioxide) On Colon Cancer Cells: Our First-Step Experience And In Vitro Results, Özgür Albuz, Di̇lek Dülger, Beste Çağdaş Tunali, Feray Aydin, Seli̇m Yalçin, Mustafa Türk Jan 2019

Effects Of B2o3 (Boron Trioxide) On Colon Cancer Cells: Our First-Step Experience And In Vitro Results, Özgür Albuz, Di̇lek Dülger, Beste Çağdaş Tunali, Feray Aydin, Seli̇m Yalçin, Mustafa Türk

Turkish Journal of Biology

Boron oxide (B2O3) is derived from dehydration of boric acid and is a colorless, semitransparent, crystalline compound that is moderately soluble in water. On the other hand, boron oxide is chemically hygroscopic. This gives the molecule the ability to soak up water and adhere to tissues. Boron oxide can be used locally after tumor debulking in inoperable tumors and especially when the tumor-free margin distance cannot be provided. For all these reasons we aimed to evaluate the in vitro test results of B2O3 in terms of cytotoxicity, genotoxicity, apoptosis, and necrotic effects on L929 fibroblast cells and DLD-1 colorectal adenocarcinoma …

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Effects Of Moisture Content, Internode Region, And Oblique Angle On The Mechanicalproperties Of Sainfoin Stem, Mustafa Gökalp Boydaş, Mustafa Çomakli, Bahadir Sayinci, Mazhar Kara Jan 2019

Effects Of Moisture Content, Internode Region, And Oblique Angle On The Mechanicalproperties Of Sainfoin Stem, Mustafa Gökalp Boydaş, Mustafa Çomakli, Bahadir Sayinci, Mazhar Kara

Turkish Journal of Agriculture and Forestry

The effects of moisture content, internode region, and oblique angle on several mechanical properties of sainfoin stem were determined. The selected mechanical properties used were the shearing stress, specific shearing energy, bending stress, and modulus of elasticity when bending. The experiments were carried out with wet basis (WB) moisture contents of 71.76%, 45.57%, and 25.57%, at the third and second internode regions from the bottom up to the top, and 2 oblique angles (0° and 28°). The research results showed that the shearing stress of sainfoin stem increased as the moisture content increased, but decreased towards the upper internode of …

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