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Evolution - #4: Genetic Drift And Founder Effect, Jessica Amacher, Sowmya Anjur, Donald Dosch, Sarah O'Leary-Driscoll, Crystal Randall

Unit 1: Evolution

Genetic drift is a term used to describe chance fluctuations in the allelic frequencies in a population over time. The effects of genetic drift tend to be very minor in large populations, but they can be quite significant in small populations. Alleles are different functional forms in which a gene might exist. Humans have two alleles, sometimes the same but sometimes different, of most of their genes. In any population, it is possible to determine the frequency of all alleles. If these alleles get passed on to the next generation at random, then we should expect to see approximately the …

Evolution - #6: Selection Simulation, Jessica Amacher, Sowmya Anjur, Donald Dosch, Sarah O'Leary-Driscoll, Crystal Randall

Unit 1: Evolution

A modern understanding of the theory of evolution revolves around the selection of certain types within a population that over long time periods eventually leads to change of the species. This descent with modification is modeled with this activity, and leads to a subsequent lesson that has students reading about research into examples of speciation.

Evolution - #5: Globin Gene Evolution, Jessica Amacher, Sowmya Anjur, Donald Dosch, Sarah O'Leary-Driscoll, Crystal Randall

Unit 1: Evolution

For this lesson, students are guided through the steps necessary to compare nucleotide and amino acid sequences available at the National Center for Biotechnology Information that is maintained by the National Institutes of Health. The lesson starts with an examination of the alpha-globin gene. Alpha-globin is one of the proteins that constitutes hemoglobin. Student look at the various sequences of this gene that have been deposited at NCBI with a goal of determining alternative forms of the gene. The lesson then broadens the scope of comparison to include members of the globin protein family. Students create a phylogenetic tree that …

Strategies To Build Economic Strength In Lagging Areas: Investment, Tax Incentives, Wage Subsidies, Worker Training, And Education, Michael Wasylenko

Economics - All Scholarship

No abstract provided.

Cellular Corrosion Of Cocrmo Total Knee Implants: Understanding Underlying Mechanisms Through Retrieval Analysis And Simulated Inflammatory Conditions, Griffin Heise

Theses and Dissertations (ETD)

Introduction. Total joint arthroplasty is considered one of the most beneficial aspects of modern orthopedic surgery. Due to the increase in population, obesity rates, and medical advances, total joint replacements have become more commonplace in the United States. Recently, a unique type of damage has been investigated in cobalt-chrome (CoCr) implants that remains poorly understood and highly controversial. Originally, it was believed that this damage type was caused by inflammatory cells directly attacking the metal surface, leading to damage of the oxide layer. However, damage caused by electrocautery tools has shown identical characteristics, leading some to believe this is the …

Wofford Today Winter 2019, Wofford College. Office Of Marketing And Communications

Wofford Today

No abstract provided.

Daily Announcements December 2019, Wofford College. Office Of Marketing And Communications

Communications Office Daily Announcements

No abstract provided.

The Negotiator's Role In A Buyer-Seller Game, Joseph Gaudy

Graduate Theses and Capstone Projects (excluding DNP)

In game theory, buyer-seller games rarely utilize a negotiating third party. Any negotiations are typically conducted by the buyer and seller. This study, motivated by the real estate market, uses sequentially and simultaneously played game models to explore the influence a self-interested, negotiating, third party has on player payoffs. For the sequential model, a game tree is utilized to demonstrate player actions, preferences, and outcomes. The weak sequential equilibrium is calculated using Gambit[1] and shows optimality in player payoffs to exist when the seller’s and realtor’s strategies align according to the current market. For the simultaneous model, expected payoff functions …

An Approach To Fast Multi-Robot Exploration In Buildings With Inaccessible Spaces, Matt Mcneill, Damian Lyons

Faculty Publications

The rapid exploration of unknown environments is a common application of autonomous multi-robot teams. For some types of exploration missions, a mission designer may possess some rudimentary knowledge about the area to be explored. For example, the dimensions of a building may be known, but not its floor layout or the location of furniture and equipment inside. For this type of mission, the Space- Based Potential Field (SBPF) method is an approach to multirobot exploration which leverages a priori knowledge of area bounds to determine robot motion. Explored areas and obstacles exert a repulsive force, and unexplored areas exert an …

Isolation, Identification, And Antibiotics Susceptibility Determination Of Proteus Species Obtained From Various Clinical Specimens In Erbil City, Treska Dhia Kamil, Sanaria Fawzi Jarjes

Polytechnic Journal

Fifty-two Proteus isolates, (47) Proteus mirabilis, (4) Proteus vulgaris, and (1) Proteus hauseri are being isolated from (200) clinical specimens taken from patients admitted to different hospitals in Erbil city/Kurdistan region of Iraq. Specimens were of urine, wounds swabs, burn swabs, vaginal swabs, ear swabs, eye swabs, and sputum. All isolates were identified depending on cultural, morphological, biochemical characteristics, and confirmatory VITEK 2 system. Furthermore, VITEK 2 (antibiotic susceptibility testing) panel was used to determine the antibiotic susceptibility of Proteus isolates, and the results showed that all isolates were entirely resistant to tetracycline and tigecycline (100%), but sensitive to meropenem. …

Detection Of Helicobacterpylori Antigens Among Patients With Gastroenteritis In Erbil City, Iraq, Karim J. S., Pshtewan D. Majeed, Kareem K. Hamad, Kareem K. Hamad

Polytechnic Journal

Helicobacter pylori is a significant pathogen of the gastrointestinal tract infection connected with gastritis, peptic ulcers, and gastric carcinoma. Its infection influence more than half of the world’s inhabitants. This study aims to reveal the prevalence rate of H. pylori infection among patients with gastroenteritis and to investigate the risk factors such as age, gender, residency, blood group and rhesus factors related to this infection in Erbil city. Of 300 stool specimens from patients presenting with gastroenteritis who were admitted to Rizgary Teaching Hospital, Erbil, Iraq, from September 2018 to February 2019 were collected and screened for the presence of …

Isolation, Identification, And Antibiotics Susceptibility Determination Of Proteus Species Obtained From Various Clinical Specimens In Erbil City, Treska Dhia Kamil, Sanaria Fawzi Jarjes

Polytechnic Journal

Fifty-two Proteus isolates, (47) Proteus mirabilis, (4) Proteus vulgaris, and (1) Proteus hauseri are being isolated from (200) clinical specimens taken from patients admitted to different hospitals in Erbil city/Kurdistan region of Iraq. Specimens were of urine, wounds swabs, burn swabs, vaginal swabs, ear swabs, eye swabs, and sputum. All isolates were identified depending on cultural, morphological, biochemical characteristics, and confirmatory VITEK 2 system. Furthermore, VITEK 2 (antibiotic susceptibility testing) panel was used to determine the antibiotic susceptibility of Proteus isolates, and the results showed that all isolates were entirely resistant to tetracycline and tigecycline (100%), but sensitive to meropenem. …

Detection Of Helicobacterpylori Antigens Among Patients With Gastroenteritis In Erbil City, Iraq, Karim J. S., Pshtewan D. Majeed, Kareem K. Hamad, Kareem K. Hamad

Polytechnic Journal

Helicobacter pylori is a significant pathogen of the gastrointestinal tract infection connected with gastritis, peptic ulcers, and gastric carcinoma. Its infection influence more than half of the world’s inhabitants. This study aims to reveal the prevalence rate of H. pylori infection among patients with gastroenteritis and to investigate the risk factors such as age, gender, residency, blood group and rhesus factors related to this infection in Erbil city. Of 300 stool specimens from patients presenting with gastroenteritis who were admitted to Rizgary Teaching Hospital, Erbil, Iraq, from September 2018 to February 2019 were collected and screened for the presence of …

Isolation, Identification, And Antibiotics Susceptibility Determination Of Proteus Species Obtained From Various Clinical Specimens In Erbil City, Treska Dhia Kamil, Sanaria Fawzi Jarjes

Polytechnic Journal

Fifty-two Proteus isolates, (47) Proteus mirabilis, (4) Proteus vulgaris, and (1) Proteus hauseri are being isolated from (200) clinical specimens taken from patients admitted to different hospitals in Erbil city/Kurdistan region of Iraq. Specimens were of urine, wounds swabs, burn swabs, vaginal swabs, ear swabs, eye swabs, and sputum. All isolates were identified depending on cultural, morphological, biochemical characteristics, and confirmatory VITEK 2 system. Furthermore, VITEK 2 (antibiotic susceptibility testing) panel was used to determine the antibiotic susceptibility of Proteus isolates, and the results showed that all isolates were entirely resistant to tetracycline and tigecycline (100%), but sensitive to meropenem. …

Detection Of Helicobacterpylori Antigens Among Patients With Gastroenteritis In Erbil City, Iraq, Karim J. S., Pshtewan D. Majeed, Kareem K. Hamad, Kareem K. Hamad

Polytechnic Journal

Helicobacter pylori is a significant pathogen of the gastrointestinal tract infection connected with gastritis, peptic ulcers, and gastric carcinoma. Its infection influence more than half of the world’s inhabitants. This study aims to reveal the prevalence rate of H. pylori infection among patients with gastroenteritis and to investigate the risk factors such as age, gender, residency, blood group and rhesus factors related to this infection in Erbil city. Of 300 stool specimens from patients presenting with gastroenteritis who were admitted to Rizgary Teaching Hospital, Erbil, Iraq, from September 2018 to February 2019 were collected and screened for the presence of …

Modeling Elementary Students’ Ideas About Heredity: A Comparison Of Curricular Interventions, Cory Forbes, Dante Cisterna, Devarati Bhattacharya, Ranu Roy

School of Natural Resources: Faculty Publications

Learning about heredity is important across the K–12 continuum. However, these ideas may be challenging for students. We examined third-grade students’ ideas about heredity in the context of a new, six-week, model-based science unit that uses corn as a model organism to support students’ ideas about heredity. We analyzed data collected during implementation of the unit, including student artifacts and interviews. We compared these data to those from a pilot version of the curriculum – implemented in the prior year – that was focused on the same disciplinary concepts but was not designed around scientific modeling. Our findings illustrate levels …

Implementing The Patient-Centered Care Paradigm In An Academic Research Environment, Fernando Orgas

Theses & Dissertations

Research Focus. The healthcare landscape is transitioning from a provider-centered care model toward greater emphasis on patient-centered care (PCC). The shift to PCC reflects efforts to increase the quality of healthcare and the care experience. The current state of research within healthcare remains focused on how to provide high-quality and sound research that will bring new equipment, procedures, and verify strategies that may benefit healthcare globally. However, changes in the healthcare atmosphere bring a new perspective to research. How is the paradigm shift to patient-centered care implemented in an academic research environment? Does this holistic mindset fully cross into …

Affordable Care Act And Preventive Care Usage: A Mixed Method Analysis Of Cardiovascular Care, Brit Peek

Theses & Dissertations

It is a commonly held belief that access to health insurance affects the level of utilization of preventive care services, and thus plays a crucial role in the effective management of avoidable chronic illnesses, decreasing levels of premature mortality, and enabling individuals to live wholesome long lives. Based on this belief, among other goals, the Affordable Care Act (ACA) was designed to increase access to health insurance and related medical services for the population of the United States. This dissertation attempts to identify whether this belief is valid or not by testing whether the usage of preventive care changed between …

Underreporting Of Patient-Reported Outcomes In Myeloproliferative Neoplasms Clinical Trials, Anthony Messina, Quentin O'Brien

Clinical Research and Leadership Faculty Posters and Presentations

Introduction

Improvements in overall survival (OS) and quality of life (QoL) are clinically relevant outcomes that should guide clinical decision-making. Patients with MPNs can live with their disease for a long period of time, which increases the importance of understanding the impact of treatment in regards to a patients’ Health-Related QoL. Therefore, including PROs in clinical trials has become paramount in facilitating informed treatment decisions made by health care providers and patients. Furthermore, the FDA encourages the implementation of patient-centric measures in clinical trials.

Objective

We aimed to evaluate the frequency at which PRO measures are utilized as study endpoints …

Quantifying Carbon Stocks Within The Androscoggin Land Trust, Olivia Lamarche, Kirsten Pelletier, Eric Viera

Community Engaged Research Reports

Greenhouse gas (GHG) emissions from the burning of fossil fuels for transportation and electricity, land use and deforestation, agriculture, and industry are causing unprecedented rates of climate change. The climate emergency is intensifying as temperature extremes increase, snow and ice cover declines, and the oceans warm and acidify. The need to mitigate climate change is rapidly increasing and many mitigation efforts focus on the reduction of GHG outputs into the atmosphere, primarily the development of new renewable energy technologies in order to reduce the burning of fossil fuels. While a decreased reliance on fossil fuels is a key climate solution, …

Computational Neuroscience, Michelle Greene, Ns/Py 357 Students

Open Educational Resources

In Fall 2019, the Computational Neuroscience class at Bates College collaborated to begin an open textbook. Eight students across three majors collaborated to present the content they were learning to students who were similar to themselves. This project serves both pedagogical and social goals. By writing for fellow students, we leveraged the power of teaching for learning. By bringing together students of diverse academic backgrounds, we leveraged the power of peer instruction. Finally, by writing in the open, students not only brought their best work forward, but are working to contribute to an open knowledge environment that democratizes information. This …

Soil Characteristics Drive Ficaria Verna Abundance And Reproductive Output, Justin P. Kermack, Emily Rauschert

Biological, Geological, and Environmental Faculty Publications

Lesser celandine (Ficaria verna Huds.), an invasive plant from Europe, is becoming widespread in river valleys throughout the northeastern United States and the Pacific Northwest. Its high rate of asexual bulbil and tuber production creates dense infestations threatening native spring ephemerals. Ficaria verna abundance and reproductive output (seeds, bulbils, and tubers) were examined in invaded transects spanning a disturbance gradient away from a river. Site characteristics (photosynthetically active radiation [PAR], soil pH, moisture, texture, and nutrients) were quantified to examine their roles in plant abundance and reproduction. A larger-scale study examined random transects not specifically chosen based on F. …

Medical School Watercooler Newsletter - December 1, 2019, Lindsey Lyle

Watercooler Newsletter

This is the December 1, 2019 edition of the Frederick P. Whiddon College of Medicine's Newsletter - Watercooler.

Contents Include:

Toldi presents at research conference in Canada

Work by USA College of Medicine researchers selected as ‘editor’s choice’

Medicine grand rounds to address perioperative care

Traumatic elbow instability topic of orthopaedic surgery grand rounds

Sugg to discuss cryptogenic stroke treatments at neurology grand rounds

Pediatric lecture series to focus on first-time seizures

Med School Café video online: 'Chronic Constipation in Children'

Bassam presents on neuromuscular therapies at national meeting

A fresh perspective: Student appreciates the art and science of medicine

Gmr36a08, Anuradha Venkatakrishnan Chimata, Oorvashi Roy Puli, Amit Singh

DVE Enhancer Sequences Utilized in GMR Line

dve enhancer 49927

• ID - GMR36A08
• Location - 2R: 18120673, 18124576
• Base pairs - 3903

Gmr40e08, Anuradha Venkatakrishnan Chimata, Oorvashi Roy Puli, Amit Singh

DVE Enhancer Sequences Utilized in GMR Line

dve enhancer 41238

• ID - GMR40E08
• Location - 2R: 18162090, 18165058
• Base pairs - 2968

Gmr36a10, Anuradha Venkatakrishnan Chimata, Oorvashi Roy Puli, Amit Singh

DVE Enhancer Sequences Utilized in GMR Line

dve enhancer 49373

• ID - GMR36A10
• Location - 2R: 18116788, 18120701
• Base pairs - 3913

Gmr39h01, Anuradha Venkatakrishnan Chimata, Oorvashi Roy Puli, Amit Singh

DVE Enhancer Sequences Utilized in GMR Line

dve enhancer 50066

• ID - GMR39H01
• Location - 2R: 18153797, 18156108
• Base pairs - 2311

Gmr42e10, Anuradha Venkatakrishnan Chimata, Oorvashi Roy Puli, Amit Singh

DVE Enhancer Sequences Utilized in GMR Line

dve enhancer

• ID - GMR42E10
• Location - 2R: 18133506, 18137474
• Base pairs - 3968

Gmr41c04, Anuradha Venkatakrishnan Chimata, Oorvashi Roy Puli, Amit Singh

DVE Enhancer Sequences Utilized in GMR Line

dve enhancer

• ID - GMR41C04
• Location -2R: 18143594, 18147064
• Base pairs - 3470

Gmr42h01, Anuradha Venkatakrishnan Chimata, Oorvashi Roy Puli, Amit Singh

DVE Enhancer Sequences Utilized in GMR Line

dve enhancer 48150

• ID - GMR42H01
• Location - 2R: 18158419, 18162751
• Base pairs - 4332