Digital Commons Network^™

Step-Up Therapy In Black Children And Adults With Poorly Controlled Asthma, Leonard B. Bacharier, Avraham Beigelman, Mario Castro, Et Al.

Open Access Publications

No abstract provided.

Cluster Analysis To Define Distinct Clinical Phenotypes Among Septic Patients With Bloodstream Infections, Maria Cristina Vazquez Guilamet, Michael Bernauer, Scott T. Micek, Marin H. Kollef

Open Access Publications

No abstract provided.

Cell Type-Specific Modulation Of Sensory And Affective Components Of Itch In The Periaqueductal Gray, Vijay K. Samineni, Jose G. Grajales-Reyes, Saranya S. Sundaram, Judy J. Yoo, Robert W. Gereau Iv

Open Access Publications

No abstract provided.

Persistence Of Right Ventricular Dysfunction And Altered Morphometry In Asymptomatic Preterm Infants Through One Year Of Age: Cardiac Phenotype Of Prematurity, Collin T Erickson, Meghna D Patel, Swati Choudhry, Karl Stessy Bisselou, Tim Sekarski, Mary Craft, Ling Li, Afif El Khuffash, Aaron Hamvas, Shelby Kutty, Gautam K Singh, Philip T Levy

Open Access Publications

INTRODUCTION: Prematurity impacts myocardial development and may determine long-term outcomes. The objective of this study was to test the hypothesis that preterm neonates develop right ventricle dysfunction and adaptive remodelling by 32 weeks post-menstrual age that persists through 1 year corrected age.

MATERIALS AND METHODS: A subset of 80 preterm infants (born <29 weeks) was selected retrospectively from a prospectively enrolled cohort and measures of right ventricle systolic function and morphology by two-dimensional echocardiography were assessed at 32 weeks post-menstrual age and at 1 year of corrected age. Comparisons were made to 50 term infants at 1 month and 1 year of age. Sub-analyses were performed in preterm-born infants with bronchopulmonary dysplasia and/or pulmonary hypertension.

RESULT: In both term and preterm infants, right ventricle function and morphology increased over the first year (p < 0.01). The magnitudes of right ventricle function measures were lower in preterm-born infants at each time period (p < 0.01 for all) and right ventricle morphology indices were wider in all preterm infants by 1 year corrected age, irrespective of lung disease. Measures of a) right ventricle function were further decreased and b) morphology increased through 1 year in preterm infants with bronchopulmonary dysplasia and/or pulmonary hypertension (p < 0.01).

CONCLUSION: Preterm infants exhibit abnormal right ventricle performance with remodelling at 32 weeks post-menstrual age that persists through 1 year corrected age, suggesting a less developed intrinsic myocardial function response …

A Promising Bioconjugate Vaccine Against Hypervirulent Klebsiella Pneumoniae, Mario F. Feldman, Anne E. Mayer Bridwell, Nichollas E. Scott, Evgeny Vinogradov, Samuel R. Mckee, Sthefany M. Chavez, Joy Twentyman, Christina L. Stallings, David A. Rosen, Christian M. Harding

Open Access Publications

No abstract provided.

Current State In Scientific Publishing: Aoa Critical Issues Symposium, Jennifer Moriatis Wolf, Linda J Sandell, Seth S Leopold, Karen L Dodson

Open Access Publications

Orthopaedic surgery has a rich history of publication of the science that supports the practice of our specialty, which dates from 1887. Orthopaedic publishing has evolved since that time, expanding from print to online access, with increasing variation in publication models, including open-access journals and article repositories, and methods of information delivery that include video, data archives, and commentary. This symposium provides an overview of the changes and challenges in the publication of orthopaedic science.

Emotional Response Inhibition Is Greater In Older Than Younger Adults, Jill D. Waring, Taylor R. Greif, Eric J. Lenze

Open Access Publications

No abstract provided.

Abcc9-Related Intellectual Disability Myopathy Syndrome Is A Katp Channelopathy With Loss-Of-Function Mutations In Abcc9, Conor Mcclenaghan, Theresa Harter, Monica Sala-Rabanal, Chris H. Emfinger, Yan Huang, Soma S. Singareddy, Colin G. Nichols, Jamie Gunn, David F. Wozniak, Attila Kovacs, Maria S. Remedi, Et Al.

Open Access Publications

No abstract provided.

The Nuclear Receptor Rev-Erbα Modulates Th17 Cell-Mediated Autoimmune Disease, Christina Chang, Chin-San Loo, Xuan Zhao, Laura A. Solt, Yuqiong Liang, Sagar P. Bapat, Han Cho, Theodore M. Kamenecka, Mathias Leblanc, Annette R. Atkins, Ruth T. Yu, Michael Downes, Thomas P. Burris, Ronald M. Evans, Ye Zheng

Open Access Publications

No abstract provided.

Uterine Natural Killer Cells, Dorothy K. Sojka, Liping Yang, Wayne M. Yokoyama

Open Access Publications

No abstract provided.

Novel Cell Adhesion/Migration Pathways Are Predictive Markers Of Hdac Inhibitor Resistance In Cutaneous T Cell Lymphoma, Jared M. Andrews, Jennifer A. Schmidt, Kenneth R. Carson, Amy C. Musiek, Neha Mehta-Shah, Jacqueline E. Payton

Open Access Publications

No abstract provided.

General Anesthesia Does Not Have Persistent Effects On Attention In Rodents, Viviane S. Hambrecht-Wiedbusch, Katherine A. Latendresse, Michael S. Avidan, Amanda G. Nelson, Margaret Phyle, Romi E. Ajluni, George A. Mashour

Open Access Publications

No abstract provided.

Longitudinal Evaluation Of Cognition After Stroke - A Systematic Scoping Review, Juan Pablo Saa, Tamara Tse, Carolyn Baum, Toby Cumming, Naomi Josman, Miranda Rose, Leeanne Carey

Open Access Publications

BACKGROUND: Cognitive impairment affects up to 80 percent of the stroke population, however, both the available evidence about post-stroke cognition and the measures used to evaluate it longitudinally have not been well described. The aims of this systematic scoping review were: to identify and characterize studies evaluating cognition longitudinally after stroke; to summarize the cognitive instruments used and the domains they target; and to organize cognitive domains assessed using the International Classification of Functioning, Disability and Health (ICF).

METHODS: We used a systematic scoping approach to search for peer-reviewed articles involving adults with stroke that evaluated cognition longitudinally. Screening of …

The Role Of Fecal Microbiota Transplantation In Reducing Intestinal Colonization With Antibiotic-Resistant Organisms: The Current Landscape And Future Directions, Michael H. Woodworth, Mary K. Hayden, Vincent B. Young, Jennie H. Kwon

Open Access Publications

No abstract provided.

The Widely Used Antimicrobial Triclosan Induces High Levels Of Antibiotic Tolerance In Vitro And Reduces Antibiotic Efficacy Up To 100-Fold In Vivo, Corey Westfall, Ana Lidia Flores-Mireles, John Isaac Robinson, Aaron J.L. Lynch, Scott Hultgren, Jeffrey P. Henderson, Petra Anne Levin

Open Access Publications

No abstract provided.

Incidence Of Acute Kidney Injury In Critically Ill Patients Receiving Vancomycin With Concomitant Piperacillin-Tazobactam, Cefepime, Or Meropenem, Adam M. Blevins, Jennifer N. Lashinsky, Craig Mccammon, Marin Kollef, Scott Micek, Paul Juang

Open Access Publications

No abstract provided.

Intestinal Macromolecular Transport Supporting Adaptive Immunity, Devesha H. Kulkarni, Rodney D. Newberry

Open Access Publications

No abstract provided.

Characterization And Validation Of An Intra-Fraction Motion Management System For Masked-Based Radiosurgery, Nels C. Knutson, Douglas Bollinger, S. Murty Goddu, James A. Kavanaugh, Lakshmi Santanam, Timothy J. Mitchell, Jacqueline E. Zoberi, Christina Tsien, Jiayi Huang, Clifford G. Robinson, Stephanie M. Perkins, Joshua L. Dowling, Michael R. Chicoine, Keith M. Rich, Gavin P. Dunn, Sasa Mutic, Et Al

Open Access Publications

No abstract provided.

Excitability And Irritability In Preschoolers Predicts Later Psychopathology: The Importance Of Positive And Negative Emotion Dysregulation, Alecia C Vogel, Joshua J Jackson, Deanna M Barch, Rebecca Tillman, Joan L Luby

Open Access Publications

Emotion dysregulation is a risk factor for the development of a variety of psychopathologic outcomes. In children, irritability, or dysregulated negative affect, has been the primary focus, as it predicts later negative outcomes even in very young children. However, dysregulation of positive emotion is increasingly recognized as a contributor to psychopathology. Here we used an exploratory factor analysis and defined four factors of emotion dysregulation: irritability, excitability, sadness, and anhedonia, in the preschool-age psychiatric assessment collected in a sample of 302 children ages 3-5 years enriched for early onset depression. The irritability and excitability factor scores defined in preschoolers predicted …

Mri Radiomic Features Are Independently Associated With Overall Survival In Soft Tissue Sarcoma, Matthew B. Spraker, Landon S. Wootton, Daniel S. Hippe, Kevin C. Ball, Jan C. Peeken, Meghan W. Macomber, Tobias R. Chapman, Michael N. Hoff, Edward Y. Kim, Seth M. Pollack, Stephanie E. Combs, Matthew J. Nyflot

Open Access Publications

No abstract provided.

Epigenetic And Therapeutic Implications Of Dnmt3b In Temporomandibular Joint Osteoarthritis, Yue Zhou, Mo Chen, Regis J. O'Keefe, Jie Shen, Zhi Li, Jian Zhou, Xuedong Zhou, Jeremy J. Mao

Open Access Publications

No abstract provided.

The Role Of Periarticular Soft Tissues In Persistent Motion Loss In A Rat Model Of Posttraumatic Elbow Contracture, Chelsey L. Dunham, Ryan M. Castile, Aaron M. Chamberlain, Spencer P. Lake

Open Access Publications

No abstract provided.

Cannabinoids, Cannabis, And Cannabis-Based Medicine For Pain Management: A Protocol For An Overview Of Systematic Reviews And A Systematic Review Of Randomised Controlled Trials, Emma Fisher, Christopher Eccleston, Louisa Degenhardt, David P. Finn, Nanna B. Finnerup, Ian Gilron, Simon Haroutounian, Elliot Krane, Andrew S.C. Rice, Michael Rowbotham, Mark Wallace, R. Andrew Moore

Open Access Publications

No abstract provided.

Lithium Chloride Corrects Weakness And Myopathology In A Preclinical Model Of Lgmd1d, Andrew R. Findlay, Rocio Bengoechea, Sara K. Pittman, Tsui-Fen Chou, Heather L. True, Conrad C. Weihl

Open Access Publications

No abstract provided.

Using Adaptive Magnetic Resonance Image‐Guided Radiation Therapy For Treatment Of Inoperable Pancreatic Cancer, Soumon Rudra, Naomi Jiang, Stephen A. Rosenberg, Jeffrey R. Olsen, Michael C. Roach, Leping Wan, Lorraine Portelance, Eric A. Mellon, Anna Bruynzeel, Frank Lagerwaard, Michael F. Bassetti, Parag J. Parikh, Percy P. Lee

Open Access Publications

No abstract provided.

Evidence Of Causal Effect Of Major Depression On Alcohol Dependence: Findings From The Psychiatric Genomics Consortium, Arpana Agrawal, Et Al

Open Access Publications

No abstract provided.

Aminophospholipids Are Signal-Transducing Trem2 Ligands On Apoptotic Cells, Keiro Shirotani, Yuma Hori, Ryohei Yoshizaki, Eri Higuchi, Marco Colonna, Takashi Saito, Shoko Hashimoto, Takashi Saito, Takaomi C. Saido, Nobuhisa Iwata

Open Access Publications

No abstract provided.

Going Beyond The Individual: How State-Level Characteristics Relate To Hpv Vaccine Rates In The United States, Melissa Franco, Stephanie Mazzucca, Margaret Padek, Ross C. Brownson

Open Access Publications

No abstract provided.

Aβ34 Is A Bace1-Derived Degradation Intermediate Associated With Amyloid Clearance And Alzheimer’S Disease Progression, Randall J. Bateman

Open Access Publications

No abstract provided.

Pigment Visibility On Rectal Swabs Used To Detect Enteropathogens: A Prospective Cohort Study, Jianling Xie, Gillian A.M. Tarr, Samina Ali, Linda Chui, Xiao-Li Pang, Bonita E. Lee, Otto G. Vanderkooi, Phillip I. Tarr, Ran Zhuo, Brendon Parsons, Byron M. Berenger, Kelly Kim, Stephen B. Freedman, Alberta Provincial Pediatric Enteric Infection Team (Appetite) And Pediatric Emergency Research Canada (Perc)

Open Access Publications

No abstract provided.