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Impulse Control Disorders In Dopamine Agonist-Treated Hyperprolactinemia: Prevalence And Risk Factors, Sunita M.C De Sousa, John Baranoff, R Louise Rushworth, Jessica Butler, Jane Sorbello, Juanita Vorster, Tanya Thompson, Ann I. Mccormack, Warrick J. Inder, David J. Torpy

Medical Papers and Journal Articles

Context: There are growing reports of dopamine agonist (DA)-induced impulse control disorders (ICDs) in hyperprolactinemic patients. However, the magnitude of this risk and predictive factors remain uncertain.

Objective: To determine ICD prevalence and risk factors in DA-treated hyperprolactinemic patients compared to community controls.

Design, Setting and Participants: Multicenter cross-sectional analysis of 113 patients and 99 healthy controls.

Main Outcome Measures: Participants completed a neuropsychological questionnaire consisting of the Depression Anxiety Stress Scale (DASS21), Questionnaire for Impulsive-Compulsive Disorders in Parkinson’s disease (QUIP-S), Hypersexual Behavior Inventory (HBI), Hypersexual Behavior Consequences Scale and Social Desirability Response Set Scale. Demographic and clinical data were …

'Through The Eyes Of The Dying' - Identifying Who May Benefit From Bereavement Follow-Up: A Qualitative Study, Jane L. Phillips, Elizabeth A. Lobb, Francis Bellemore, Terrence Hays, David C. Currow

Medical Papers and Journal Articles

Introduction: Bereavement support is an integral element of palliative care. Emerging evidence stipulates that bereavement support should be reserved for those most at risk of poor outcomes. While this evidence makes identifying those at risk of experiencing a complex bereavement a necessary first step, it has been difficult to arrive at a consensus as to whom that should be.

Aim: To explore whether palliative care in-patients with advanced disease are concerned about the bereavement needs of others and, if so, is it their next-of-kin.

Design: A qualitative study using semi-structured interviews, and thematic analysis using a constant comparative method.

Setting/participants: …

Combining Unassisted And Robot-Guided Practice Benefits Motor Learning For A Golf Putting Task, Stephen R. Bested, Gerome A. Manson, Luc Tremblay

Medical Papers and Journal Articles

Robotic guidance has been employed with limited effectiveness in neurologically intact and patient populations. For example, our lab has effectively used robotic guidance to acutely improve movement smoothness of a discrete trajectory without influencing movement endpoint distributions. The purpose of the current study was to investigate the efficacy of combining robotic guidance and unassisted trials in the learning of a golf putting task. Participants completed a pre-test, an acquisition phase, and an immediate and delayed (24-hour) post-test. During the pre-test, kinematic data from the putter was converted into highly accurate, consistent, and smooth trajectories delivered by a robot arm. During …

Familial Hypercholesterolaemia In 2020: A Leading Tier 1 Genomic Application, Jing Pang, David R. Sullivan, Tom Brett, Karam M. Kostner, David L. Hare, Gerald F. Watts

Medical Papers and Journal Articles

Familial hypercholesterolemia (FH) is caused by a major genetic defect in the low-density lipoprotein (LDL) clearance pathway. Characterised by LDL-cholesterol elevation from birth, FH confers a significant risk for premature coronary artery disease (CAD) if overlooked and untreated. With risk exposure beginning at birth, early detection and intervention is crucial for the prevention of CAD. Lowering LDL-cholesterol with lifestyle and statin therapy can reduce the risk of CAD. However, most individuals with FH will not reach guideline recommended LDL-cholesterol targets. FH has an estimated prevalence of approximately 1:250 in the community. Multiple strategies are required for screening, diagnosing and treating …

Managing Anxiety Disorders In Adults, Gregory Wilkins, Gavin Andrews, Caroline Bell, Philip Boyce, Christopher Gale, Ronald Rapee, Lisa Lampe

Medical Papers and Journal Articles

The GP has a key role in identifying patients presenting with anxiety symptoms and ensuring appropriate acute and long-term management. There are two key messages for GPs to follow: once you have made a diagnosis of an anxiety disorder, tell the patient you have a treatment for it. Second, do not let your anxiety lead you to prescribe inappropriately or overinvestigate for all possible differential diagnoses.

Career Sponsorship: An Effective Way For Developing Women Leaders, Jovina Ang

Research Collection Lee Kong Chian School Of Business

Other than an effective career progression strategy, this research, which comprised of an autoethnography and an in-depth qualitative case study research showed that career sponsorship could be an effective strategy for developing women leaders. In the sponsor relationship, sponsors invest considerable time, effort and resources in developing sponsees, thus, preparing them for the top jobs. In addition to developing the skills on the leadership strataplex, career sponsorship has been shown to be an enabler for developing confidence, which is one of the necessary ingredients for developing executive presence. Career sponsorship also fills the gap and addresses the shortcomings that arise …

Does Having A Bad Boss Make You More Likely To Be One Yourself?, Shannon G. Taylor, Robert Folger, Abhijeet K. Vadera, Matthew D. Griffith, Chaim R. Letwin

Research Collection Lee Kong Chian School Of Business

Toxic bosses harm employees in countless ways — for instance, by lowering morale, diminishing well-being, and increasing work-family conflict. Estimates suggest abusive supervision costs organizations millions in lost productivity, employee turnover, and litigation each year. Although prior research has found that leader behaviors can “trickle down” to affect the actions of employees at lower organizational levels, surely not all abused supervisors abuse their own subordinates. So when do supervisors perpetuate abuse in organizations, when don’t they, and why?

Third Party Employment Branding: What Are Its Signaling Dimensions, Mechanisms, And Sources?, Brian R. Dineen, Greet Van Hoye, Filip Lievens, Lindsay Mechem Rosokha

Research Collection Lee Kong Chian School Of Business

Massive shifts in the recruitment landscape, the continually changing nature of work and workers, and extraordinary technological progress have combined to enable unparalleled advances in how current and prospective employees receive and process information about organizations. Once the domain of internal organizational public relations and human resources (HR) teams, most employment branding has moved beyond organizations’ control. This chapter provides a conceptual framework pertaining to third party employment branding, defined as communications, claims, or status-based classifications generated by parties outside of direct company control that shape, enhance, and differentiate organizations’ images as favorable or unfavorable employers. Specifically, the authors first …

Assessing Meaningful Within-Person Variability In Likert-Scale Rated Personality Descriptions: An Irt Tree Approach, Jonas W. B. Lang, Filip Lievens, Filip De Fruyt, Ingo Zettler, Jennifer L. Tackett

Research Collection Lee Kong Chian School Of Business

Personality researchers and clinical psychologists have long been interested in withinperson variability in a given personality trait. Two critical methodological challenges that stymie current research on within-person variability are separating meaningful within-person variability from 1) true differences in trait level and 2) careless responding (or person unreliability). To partly avoid these issues, personality researchers commonly only study within-person variability in personality states over time using the standard deviation (SD) across repeated measurements of the same items (typically across days)—a relatively resource-intensive approach. In this article, we detail an approach that allows researchers to measure another type of within-person variability. The …

In Their Own Words: A Qualitative Study Exploring Influences On The Food Choices Of University Students, Michelle Lambert, Paola Chivers, Fiona Farringdon

Health Sciences Papers and Journal Articles

Issue addressed: University students generally make independent decisions regarding food choices. Current research about knowledge of Australian Dietary Guidelines (ADG), sources of nutrition information and influences on food choices for this group is scarce.

Methods: Qualitative data were collected from gender‐separated focus groups comprising four female (n = 31) and four male (n = 18) to identify: knowledge of ADG; sources of nutrition information; factors that influence food choices; perceived relevant nutrition messages and how best to deliver them.

Results: Gaps in knowledge were identified particularly regarding number of serves and serving size for food groups. Social media was the …

Role Of Organizational Culture In Psychological Needs Satisfaction And Work Engagement, Quddsia Sadaf, Mudassar Aziz, Gulnaz Anjum

Business Review

This paper explores the role of organizational culture in the satisfaction of basic psychological needs and yielding work engagement among public and private sector managers. Results reveal that organizational culture confers employees with a sense of relatedness which promotes work engagement. Additionally, the study suggests that female managers have a higher need for relatedness, the satisfaction of all basic psychological needs is significantly higher among private sector employees and work satisfaction increases with increasing job level. This study can be used for the development of organizational culture to improve relatedness among employees with respect to gender and the type of …

The Wild Beasts, Peter Cochrane

Theses and Dissertations

The Wild Beasts springs from my desire to thank my ever-expanding queer chosen family and mentors for their strength. Working through the often violent and othering aspects of the lens and photographic histories I create floral portraits responding to each person’s being and our relationship. Using the 19th century, 8x10 large format view camera—the same used by colonialists and ethnographers to “capture” the divinity of Nature—I erect each as a traditional still life studio setup at the threshold between the natural world and that constructed by humans. These environments speak both to the character of each friend and also to …

Variable- And Person-Centered Approaches To Examining Construct-Relevant Multidimensionality In Writing Self-Efficacy, Morgan Debusk-Lane

Theses and Dissertations

Writing self-efficacy is a vital component to a students’ motivation and will to succeed towards writing. The measurement of writing self-efficacy over the past 40 years, despite its development, continues to largely be represented by Confirmatory Factor Analysis models that are limited due to their restricted item to factor constraints. These constraints, given prior literature and the theoretical understanding of self-efficacy, do not adequately model construct- relevant psychometric multidimensionality as a product of conceptual overlap or a hierarchical or general factor. Given this, the present study’s purpose was to examine the adapted Self-efficacy for Writing Scale (SEWS) for the presence …

Structure-Activity Relationship Studies Of Synthetic Cathinones And Related Agents, Rachel A. Davies

Theses and Dissertations

Synthetic cathinones and related agents represent an international drug abuse problem, and at the same time an important class of clinically useful compounds. Structure-activity relationship studies are needed to elucidate molecular features underlying the pharmacology of these agents. Illicit methcathinone (i.e., MCAT), the prototype of the synthetic cathinone class, exists as a racemic mixture. Though the differences in potency and target selectivity between the positional and optical isomers of synthetic cathinones and related agents have been demonstrated to have important implications for abuse and therapeutic potential, the two MCAT isomers have never been directly compared at their molecular targets: the …

Training Future Mental Health Professionals In An Evidence-Informed System Of Care, Julia R. Cox

Theses and Dissertations

High quality mental health services do not reach the youth who need them, leading to efforts to implement effective treatments more broadly. One focus of these efforts concerns training the mental health workforce, of which master’s-level social workers represent a large proportion. However, the curricula of master’s in social work (MSW) programs do not often emphasize evidence-based approaches. One possible solution is Managing and Adapting Practice (MAP; PracticeWise, LLC), a system that allows clinicians to (1) identify clinically indicated evidence-based programs by searching a growing evidence-base of randomized controlled trials (RCTs) and (2) build individualized evidence-informed treatment plans by focusing …

From Sunrise To Sunset: A Lifespan Approach To Understanding The Mental Health Of A Subset Of American Farmers, Janna L. Imel

Theses and Dissertations

Prior research has indicated higher risk of suicide for farmers and identified depression and anxiety as mental health concerns, though the majority of research was conducted in the 1980s-1990s. In today’s economic, social, and political climate, farmers are exposed to situations and stressors reminiscent of the 1980s Farm Crisis. An added risk is the aging workforce of farmers, as age-related conditions can make farming even riskier. This study investigated the mental health of a subset of American farmers by exploring farm-related stressors, coping mechanisms, and mental health outcomes. Dispositional mindfulness was explored as a specific coping mechanism. Participants (N …

Do Sluggish Cognitive Tempo Symptoms Improve With School-Based Adhd Interventions? Outcomes And Predictors Of Change., Zoe Smith

Theses and Dissertations

Sluggish cognitive tempo (SCT) is a construct that includes symptoms of slowness, mental confusion, excessive daydreaming, low motivation, and drowsiness/sleepiness. SCT is often co-morbid with attention-deficit/hyperactivity disorder (ADHD), and SCT symptoms are associated with significant academic and interpersonal impairment above and beyond the influence of ADHD symptoms. Despite the overlap between ADHD and SCT and associated impairments, no studies have evaluated how evidence-based psychosocial interventions for adolescents with ADHD impact symptoms of SCT. This study examined whether SCT symptoms improved in a sample of 274 young adolescents with ADHD who received either an organizational skills or a homework completion intervention. …

An Adaptation And Psychometric Evaluation Of The Teacher Attribution Measure For Early Elementary (Tam-Ee), Shannon L. Nemer

Theses and Dissertations

This study examined the reliability and validity of the Teacher Attribution Measure for Early Elementary (TAM-EE), a measure adapted from the Preschool Teaching Attributions (PTA) measure, to assess the challenging behavior attributions of early elementary teachers. Like the PTA, the TAM-EE uses a series of student-specific behavior scenarios as prompts for teachers who then rate statements aligned with dimensions of attribution theory on a 6-point scale. A sample of 41 teachers completed the TAM-EE on 79 students in grades K-3 screened for risk of emotional and behavioral disorders (EBD). Teachers also completed reports of student behavior, self-efficacy, and perceptions of …

Investigating Daily Writing Emotions, Attention Regulation, And Productivity: An Intensive Longitudinal Study, Eric Ekholm

Theses and Dissertations

Emotions pervade academic situations and influence the ways that learners think, behave, and achieve (Pekrun, 2006; Schutz & Lanehart, 2002). Writing may be a particularly emotion-laden activity, and especially so for students concentrating in fields that value writing production. However, very few studies have quantitatively investigated writers’ emotional experiences. The goal of the current study was to examine the writing-related emotions of graduate students enrolled in writing-intensive disciplines as well as how these emotions related to writers’ daily productivity and attention-regulation behaviors. To do so, the study employed a daily diary design (Gunthert & Wenze, 2012) in which participants completed …

Teacher-Child Relationships, Interactions, And Problem Behavior: A Longitudinal Analysis Examining Bi-Directional Associations, Rachel Kunemund

Theses and Dissertations

A number of preschool children engage in consistent problem behaviors that place them at-risk for developing emotional and behavioral disorders. These problem behaviors have been associated with poorer short and long-term outcomes for young children. Teacher-child relationships (i.e. conflict and closeness) and positive interactions between teachers and children may be reciprocally associated with problem behavior (e.g. teacher-child closeness reducing problem behavior). The purpose of this study was to explore the longitudinal bi-directional relations between teacher-child relationships, teacher-child interactions, and problem behavior over a single school year. Using a cross-lagged panel model, data from a larger randomized control trial of the …

The Influence Of Electronic Cigarette Heating Coil Resistance On Nicotine Delivery, Heart Rate, Subjective Effects, And Puff Topography, Marzena M. Hiler

Theses and Dissertations

Electronic cigarette (ECIG) users can manipulate several device features including liquid nicotine concentration (mg/ml) and heating coil resistance (Ohms). One class of ECIG models, called “sub-Ohm” devices, use coils with a resistance of < 1 Ohms, lower than those observed in conventional ECIGs (e.g., ≥ 1.5 Ohms). Increasing voltage or decreasing coil resistance increases device power. Given that ECIG coil resistance and liquid nicotine concentration have not been manipulated systematically and simultaneously in clinical laboratory studies, the influence of these factors on ECIG acute effects remain unclear. The primary purpose of this study was to examine the influence of coil resistance and liquid nicotine concentration on nicotine delivery, heart rate (HR), subjective effects, puff topography, and liquid consumption.

Thirty-two experienced ECIG users completed four independent laboratory sessions that differed by coil resistance (0.5Ohm or 1.5Ohm ) and liquid nicotine concentration (3 or 8 mg/ml). In each session, participants used a 4.5 V “Kanger SUBOX” loaded with 3.5 ml ECIG liquid in a 10-puff directed and 60-minute ad libitum bout. Nicotine delivery was greatest when using 8 mg+0.5Ohm combination and lowest when using the 3 mg/ml+1.5Ohm …

Axon Initial Segment Integrity In Aging And Traumatic Brain Injury, Mazen M. Gouda

Theses and Dissertations

According to the Center for Disease Control’s (CDC) report to the Congress, there are 2.2 million emergency department visits; 80,000 hospitalizations; and 50,000 deaths each year due to traumatic brain injury. Adults 65 years and older account substantially for the majority of the hospitalization and deaths. Over 70% of the traumatic brain injuries of the older adults are classified as mild to moderate; however, even with these milder injuries, older adults present with a significantly higher morbidity and mortality compared to all other age groups (LeBlanc et al., 2006). With that in mind, it seems essential to develop a deeper …

Etiological Contributions Of Genetic And Environmental Factors To Nonmedical Use Of Prescription Drugs Among Young Adults, Cassie Overstreet

Theses and Dissertations

Key variables such as trauma exposure (TE) and internalizing symptoms (e.g., posttraumatic stress disorder [PTSD]) have been shown to correlate with non-medical use of prescription drugs (NMUPD); however, the temporal associations between these phenotypes remain poorly understood. Moreover, there is a paucity of research that incorporates the influence of genetic factors in the etiology of NMUPD. Although it has been demonstrated that drug use disorders are moderately heritable, research aimed at identifying the specific genes conferring risk is virtually non-existent for NMUPD. Therefore, determining the contribution of genetic and environmental factors associated with risk is critical to understanding NMUPD. To …

Factors That Influence Mental Health Services Utilization By Children Who Have Experienced Adversity, Mary B. Stebbins

Theses and Dissertations

Adverse childhood experiences (ACEs) are linked to increased mental health problems in children, but their association with mental health services utilization is not well known. This secondary analysis used 2016 National Survey of Children’s Health data from two samples: children aged 6-17-years-old with a mental or behavioral condition in need of treatment or counseling (N = 5,723); and a subsample of children who experienced at least one ACE (n = 3,812). Multiple logistic regression and latent class analysis (LCA) were performed to examine the association between ACEs and mental health services utilization. Multiple logistic regressions also examined the …

The Effects Of Notch Signaling On Functional Recovery Following Traumatic Brain Injury, Jyoti Lodha

Theses and Dissertations

2.5 million people sustain a traumatic brain injury (TBI) annually in the United States. Although there is potential for functional recovery following TBI, there is no definitive treatment to improve recovery after TBI. Our lab has shown that TBI enhances an endogenous neurogenic response in the subventricular zone and hippocampus. TBI-induced neural stem cells (NSCs) can integrate into regions such as the hippocampus and olfactory bulb. Although the mechanism behind TBI-enhanced neurogenesis remains unknown, the Notch signaling pathway has been implicated as a regulator in the maintenance and survival of NSCs.

This thesis explores the effects of Notch pathway manipulation …

Exploring The Standard: A Look Into Modern Voice And Speech Curriculum, Taylor L. Bosta

Theses and Dissertations

This thesis explores the current state of voice and speech education to discover if there is a standard of learning from university to university. By examining the history of voice and speech, discovering basic skills, breaking down teaching methodologies, and taking a look at current university and conservatory acting programs, the thesis discovers there is not a standard way of teaching, but there is a standard set of skills that should be upheld when planning voice and speech curriculum.

When Empathy Only Goes So Far: Development Of A Trait Parochial Empathy Scale, Anna Maria C. Behler

Theses and Dissertations

Empathy, the ability to feel and/or understand another’s emotional state, plays a significant role in interpersonal interactions, mitigating hostility and enhancing affiliation and helping. However, empathy also biases interpersonal reactions. For example, at the group level empathy can become amplified towards members of their ingroup and blunted towards individuals in outgroups, a term called parochial empathy. Currently, no validated measures of parochial empathy at the dispositional level exist, and development of such a scale would be important to understanding the role of group-based emotions in prejudice and discrimination against outgroups. I conducted five studies to develop and validate a …

Analyzing Interactions Between Methcathinone Analogs And The Human Monoamine Transporters, Vy Nguyen

Theses and Dissertations

Psychostimulants elicit their psychological and behavioral effects through interactions with the monoamine transporters. These compounds are classified as either substrates or reuptake inhibitors, depending on their mechanism of action, and have varying potencies at the three human monoamine transporters, hDAT, hSERT, and hNET. Substrates and reuptake inhibitors also have distinct electrophysiological signatures: reuptake inhibitors cause hyperpolarization in HEK293 cells stably expressing the monoamine transporters, whereas substrate transport mediates a depolarizing current. Recent studies have shown that substrate-mediated depolarization is sufficient to activate L-type calcium channels, a characteristic which has been used to develop a novel calcium assay which uses calcium …

Determining Success Factors In Interprofessional Practice With Dynamic Teams, Danah Alsane

Theses and Dissertations

Background: The interprofessional healthcare team is dynamic to cope with complex issues and needs existing in the healthcare environment. Understanding the important factors that predict dynamic team effectiveness helps health educators to establish team training models that focus on improving collaborative student performance that facilitates their transition to practice and helps to improve the health and system outcomes.

Objectives:1) Assess the impact of a practice-based interprofessional education (IPE) model on student attitudes and knowledge toward interprofessional teamwork.2) Evaluate predictors associated with team effectiveness among dynamic student teams participating in a practice-based IPE setting.

Methods: This was an exploratory cross-sectional …

Dating Violence And Latina/O Emerging Adult’S Attitudes Towards Condoms And Condom Use Behaviors: Examining The Role Of Culture, Melissa Avila

Theses and Dissertations

Latina/o emerging adults living in southern states may be especially at risk of being disproportionately affected by HIV. In 2015, Latina/os aged 20 to 24 accounted for 14.7% of all 20-24-year old’s living with HIV in southern states, despite the fact that 20 to 24-year-olds make up 3.7% of the region’s overall population of individuals living with HIV (CDC, 2016; U.S. Census Bureau, 2017). Specifically, there continues to be groups of Latina/o emerging adults who do not use condoms when they are sexually active and who are not using condoms consistently. Condom use literature suggests that relationship factors, such as …