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2019

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Alkaline Phosphatase: A Potential Biomarker For Stroke And Implications For Treatment, A L. Brichacek, C M. Brown Feb 2019

Alkaline Phosphatase: A Potential Biomarker For Stroke And Implications For Treatment, A L. Brichacek, C M. Brown

Clinical and Translational Science Institute

Stroke is the fifth leading cause of death in the U.S., with more than 100,000 deaths annually. There are a multitude of risks associated with stroke, including aging, cardiovascular disease, hypertension, Alzheimer’s disease (AD), and immune suppression. One of the many challenges, which has so far proven to be unsuccessful, is the identification of a cost-effective diagnostic or prognostic biomarker for stroke. Alkaline phosphatase (AP), an enzyme first discovered in the 1920s, has been evaluated as a potential biomarker in many disorders, including many of the co-morbidities associated with stroke. This review will examine the basic biology of AP, and …


February 2019, Sarah Yount Feb 2019

February 2019, Sarah Yount

Wellness Committee Minutes

No abstract provided.


Prostate Cancer Disparity, Chemoprevention, And Treatment By Specific Medicinal Plants, Clement G. Yedjou, Ariane T. Mbemi, Felicite Noubissi, Solange S. Tchounwou, Nole Tsabang, Marinelle Payton, Lucio Miele, Paul B. Tchounwou Feb 2019

Prostate Cancer Disparity, Chemoprevention, And Treatment By Specific Medicinal Plants, Clement G. Yedjou, Ariane T. Mbemi, Felicite Noubissi, Solange S. Tchounwou, Nole Tsabang, Marinelle Payton, Lucio Miele, Paul B. Tchounwou

Faculty and Student Publications

© 2019 by the authors. Licensee MDPI, Basel, Switzerland. Prostate cancer (PC) is one of the most common cancers in men. The global burden of this disease is rising. Its incidence and mortality rates are higher in African American (AA) men compared to white men and other ethnic groups. The treatment decisions for PC are based exclusively on histological architecture, prostate-specific antigen (PSA) levels, and local disease state. Despite advances in screening for and early detection of PC, a large percentage of men continue to be diagnosed with metastatic disease including about 20% of men affected with a high mortality …


New Haven Food Action Plan (2019), New Haven Food Policy Council Feb 2019

New Haven Food Action Plan (2019), New Haven Food Policy Council

Reports

No abstract provided.


Physical Activity, Muscle-Strengthening Activities, And Systemic Inflammation Among Retinopathy Patients, Emily Frith, Paul D. Loprinzi Feb 2019

Physical Activity, Muscle-Strengthening Activities, And Systemic Inflammation Among Retinopathy Patients, Emily Frith, Paul D. Loprinzi

Faculty and Student Publications

© 2018 by the American Diabetes Association. Objective. We evaluated the specific association between muscle-strengthening activity (MSA) and accelerometer-assessed physical activity on systemic inflammation among retinopathy patients in the United States. Methods. Data from the 2005–2006 National Health and Nutrition Examination Survey (NHANES) were used to identify 157 retinopathy patients between 40 and 85 years of age with complete data on select study variables. MSA was assessed via self-report. Participation in moderate-to-vigorous physical activity (MVPA) was determined from objective accelerometer data. Systemic inflammation was assessed using C-reactive protein (CRP), which was quantified using latex-enhanced nephelometry. Nonproliferative retinopathy was determined using …


Uni Grad Student News, V17n3, February 2019, University Of Northern Iowa. Graduate College. Feb 2019

Uni Grad Student News, V17n3, February 2019, University Of Northern Iowa. Graduate College.

UNI Grad Student News

Inside This Issue:
--Take Care Tips From the Graduate College
--Student Profile
--Alumni Profile
--New Office On Campus
--Getting Involved On Campus and The Community
--Fall Commencement 2018
--Faculty Profile
--Reflections of an Alumni Events for Graduate Students
--Student Accolades


February/March 2019, Issue 5, James Madison University Uhc Marketing Team Feb 2019

February/March 2019, Issue 5, James Madison University Uhc Marketing Team

Potty Mouth

No abstract provided.


Rescheduled | Steam (Science, Technology, Engineering, Arts, And Math) Industry Panel, Feb. 6, Ohio University College Of Arts & Sciences Feb 2019

Rescheduled | Steam (Science, Technology, Engineering, Arts, And Math) Industry Panel, Feb. 6, Ohio University College Of Arts & Sciences

All Forum Articles

No abstract provided.


Association Between Perceived Physical Activity And Cognitive Function In Older Adults, Paul D. Loprinzi, Emily Frith Feb 2019

Association Between Perceived Physical Activity And Cognitive Function In Older Adults, Paul D. Loprinzi, Emily Frith

Faculty and Student Publications

© The Author(s) 2018. There is irrefutable evidence that regular participation in physical activity is favorably associated with numerous positive health outcomes, including cognitive function. Emerging work suggests that perceived physical activity, independent of actual physical activity behavior, is inversely associated with mortality risk. In this study, we evaluate whether perceived physical activity, independent of actual physical activity, is associated with cognitive function, a robust indicator of mortality risk. Data from the cross-sectional 1999–2002 National Health and Nutrition Examination Survey were employed (N = 2352; 60+ years of age). Actual physical activity was assessed via a validated survey. Perceived physical …


Seasonal Home Ranges And Habitat Selection Of Three Elk (Cervus Elaphus) Herds In North Dakota, Jacqueline C. Amor, Robert Newman, William F. Jensen, Bradley Rundquist, W. David Walter, Jason R. Boulanger Feb 2019

Seasonal Home Ranges And Habitat Selection Of Three Elk (Cervus Elaphus) Herds In North Dakota, Jacqueline C. Amor, Robert Newman, William F. Jensen, Bradley Rundquist, W. David Walter, Jason R. Boulanger

Biology Faculty Publications

Changes in land use have resulted in range shifts of many wildlife species, including those entering novel environments, resulting in the critical need to understand their spatial ecology to inform ecosystem effects and management decisions. Dispersing elk (Cervus elaphus) were colonizing areas of suitable habitat in the Northern Great Plains, USA, resulting in crop depredation complaints in these areas. Although state resource managers had little information on these elk herds, limited evidence suggested temporal movements into Canada. We collected and analyzed essential information on home range and habitat selection for 3 elk herds residing in North Dakota. We …


Use Of Physical Activity Monitoring Devices By Families In Rural Communities: Qualitative Approach, Iryna Sharaievska, Rebecca A. Battista, Jennifer Zwetsloot Feb 2019

Use Of Physical Activity Monitoring Devices By Families In Rural Communities: Qualitative Approach, Iryna Sharaievska, Rebecca A. Battista, Jennifer Zwetsloot

Publications

Background: Several studies support the impact of information communication technology–based interventions to promote physical activity among youth. However, little is known on how technology can be used by the entire family to encourage healthy behavior. Previous studies showed that children and youth rely and are dependent upon the decisions and values of their caregivers when it comes to having a healthy lifestyle. Thus, the exploration of behavior and attitudes of the entire family is needed.

Objective: The study aimed to explore (1) perceptions of how the use of physical activity tracking devices (Fitbit Zip) by families in rural communities influence …


Bioo 433.01: Plant Physiology, Anna Sala Feb 2019

Bioo 433.01: Plant Physiology, Anna Sala

University of Montana Course Syllabi

No abstract provided.


Biol 435.01: Comparative Animal Physiology, Art Woods Feb 2019

Biol 435.01: Comparative Animal Physiology, Art Woods

University of Montana Course Syllabi

No abstract provided.


Bioh 457.80: Cadaver Dissection Ii, Laurie A. Minns Feb 2019

Bioh 457.80: Cadaver Dissection Ii, Laurie A. Minns

University of Montana Course Syllabi

No abstract provided.


Critical Role Of Post-Transcriptional Regulation For Ifn-Γ In Tumor-Infiltrating T Cells, Fiamma Salerno, Aurelie Guislain, Julian J. Freen-Van Heeren, Benoit P. Nicolet, Howard A. Young, Monika C. Wolkers Feb 2019

Critical Role Of Post-Transcriptional Regulation For Ifn-Γ In Tumor-Infiltrating T Cells, Fiamma Salerno, Aurelie Guislain, Julian J. Freen-Van Heeren, Benoit P. Nicolet, Howard A. Young, Monika C. Wolkers

United States Public Health Resources

Protective T cell responses against tumors require the production of Interferon gamma (IFN-γ). However, tumor-infiltrating T cells (TILs) gradually lose their capacity to produce IFN-γ and therefore fail to clear malignant cells. Dissecting the underlying mechanisms that block cytokine production is thus key for improving T cell products. Here we show that although TILs express substantial levels of Ifng mRNA, post-transcriptional mechanisms impede the production of IFN-γ protein due to loss of mRNA stability. CD28 triggering, but not PD1 blocking antibodies, effectively restores the stability of Ifng mRNA. Intriguingly, TILs devoid of AU-rich elements within the 3ʹuntranslated region maintain stabilized …


Genetic Loci Associated With Salt Tolerance In Advanced Breeding Populations Of Tetraploid Alfalfa Using Genome-Wide Association Studies, Xiang-Ping Liu, Charles Hawkins, Michael D. Peel, Long-Xi Yu Feb 2019

Genetic Loci Associated With Salt Tolerance In Advanced Breeding Populations Of Tetraploid Alfalfa Using Genome-Wide Association Studies, Xiang-Ping Liu, Charles Hawkins, Michael D. Peel, Long-Xi Yu

Plants, Soils, and Climate Faculty Publications

Many agricultural lands in the western United States consist of soil with high concentrations of salt, which is detrimental to alfalfa (Medicago sativa L.) growth and production, especially in the region where water resource is limited. Developing alfalfa varieties with salt tolerance is imperative for sustainable production under increasing soil salinity. In the present study, we used advanced alfalfa breeding populations and evaluated five traits related to salt tolerance including biomass dry weight (DW) and fresh weight (FW), plant height (PH), leaf relative water content (RWC), and stomatal conductance (SC) under control and salt stress. Stress susceptibility index (SSI) …


Diabetes Prevalence Survey Of Pakistan (Dps-Pak): Prevalence Of Type 2 Diabetes Mellitus And Prediabetes Using Hba1c: A Population-Based Survey From Pakistan, Azizul L Hasan Aamir, Saeed A. Mahar, Faisal Masood Qureshi, Ibrar Ahmad, Ali Jawa, Aisha Sheikh, Abbas Raza, Sheraz Fazid, Zahid Jadoon, Osama Ishtiaq Feb 2019

Diabetes Prevalence Survey Of Pakistan (Dps-Pak): Prevalence Of Type 2 Diabetes Mellitus And Prediabetes Using Hba1c: A Population-Based Survey From Pakistan, Azizul L Hasan Aamir, Saeed A. Mahar, Faisal Masood Qureshi, Ibrar Ahmad, Ali Jawa, Aisha Sheikh, Abbas Raza, Sheraz Fazid, Zahid Jadoon, Osama Ishtiaq

Section of Diabetes, Endocrinology and Metabolism

Objectives: We conducted a Pakistan-wide community-based survey on the prevalence of type 2 diabetes using glycated haemoglobin (HbA1c) as the screening test. The aim was to estimate diabetes prevalence across different demographic groups as well as all regions of Pakistan.

Design, settings and participants: Multistaged stratified cluster sampling was used for the representative selection of people aged ≥20 years, residing in 378 sampled clusters of 16 randomly selected districts, in this cross-sectional study. Eligible participants had blood drawn for HbA1c analyses at field clinics near to their homes. The oral glucose tolerance test (OGTT) was conducted on a subsample of …


A Multicountry Randomized Controlled Trial Of Comprehensive Maternal Nutrition Supplementation Initiated Before Conception: The Women First Trial., K. Michael Hambidge, Jamie E. Westcott, Ana Garcés, Lester Figueroa, Shivaprasad S. Goudar, Sangappa M. Dhaded, Omrana Pasha, Sumera A. Ali, Antoinette Tshefu, Adrien Lokangaka, Richard J. Derman, Robert L. Goldenberg, Carl L. Bose, Melissa Bauserman, Marion Koso-Thomas, Vanessa R. Thorsten, Amaanti Sridhar, Kristen Stolka, Abhik Das, Elizabeth M. Mcclure, Nancy F. Krebs Feb 2019

A Multicountry Randomized Controlled Trial Of Comprehensive Maternal Nutrition Supplementation Initiated Before Conception: The Women First Trial., K. Michael Hambidge, Jamie E. Westcott, Ana Garcés, Lester Figueroa, Shivaprasad S. Goudar, Sangappa M. Dhaded, Omrana Pasha, Sumera A. Ali, Antoinette Tshefu, Adrien Lokangaka, Richard J. Derman, Robert L. Goldenberg, Carl L. Bose, Melissa Bauserman, Marion Koso-Thomas, Vanessa R. Thorsten, Amaanti Sridhar, Kristen Stolka, Abhik Das, Elizabeth M. Mcclure, Nancy F. Krebs

Global Health Articles

Background: Reported benefits of maternal nutrition supplements commenced during pregnancy in low-resource populations have typically been quite limited.

Objectives: This study tested the effects on newborn size, especially length, of commencing nutrition supplements for women in low-resource populations ≥3 mo before conception (Arm 1), compared with the same supplement commenced late in the first trimester of pregnancy (Arm 2) or not at all (control Arm 3).

Methods: Women First was a 3-arm individualized randomized controlled trial (RCT). The intervention was a lipid-based micronutrient supplement; a protein-energy supplement was also provided if maternal body mass index (kg/m2) was(DRC), Guatemala, India, and …


Towards Multi-Lingual Pneumonia Research Data Collection Using The Community-Acquired Pneumonia International Cohort Study Database, William A. Mattingly, Kimberley A. Buckner, Senen Pena Feb 2019

Towards Multi-Lingual Pneumonia Research Data Collection Using The Community-Acquired Pneumonia International Cohort Study Database, William A. Mattingly, Kimberley A. Buckner, Senen Pena

The University of Louisville Journal of Respiratory Infections

Background: Although multilingual interfaces are preferred by most users when they have a choice, organizations are often unable to support and troubleshoot problems involving multiple user languages. Software that has been structured with multiple languages and data interlinking considerations early in its development is more likely to be easily maintained. We describe the process of adding multilingual support to the CAPO international Cohort study database using REDCap.

Methods: Using Google Translate API we extend the supported Spanish language version of REDCap to the most recent version used by CAPO, 8.1.4. We then translate the English data dictionary for CAPO to …


Forage News [2019-02], Department Of Plant And Soil Sciences, University Of Kentucky Feb 2019

Hexapod Herald - Vol. 31, No. 1, February 2019 Feb 2019

Hexapod Herald - Vol. 31, No. 1, February 2019

Hexapod Herald and Other Entomology Department Newsletters

Welcome -- Congratulations -- Note from John Ruberson -- Grants -- Faculty News -- Student News -- Publications -- Blast from the Past -- Brewer Appreciation Reception -- Intro Beekeeping Class-Year 1 -- Condolences -- Retirement Reception for Kalisch and Roselle


A Critical Analysis On Offenders Rehabilitation Approach In South Africa: A Review Of The Literature, Patrick Bashizi Bashige Murhula, Shanta B. Singh Feb 2019

A Critical Analysis On Offenders Rehabilitation Approach In South Africa: A Review Of The Literature, Patrick Bashizi Bashige Murhula, Shanta B. Singh

African Journal of Criminology and Justice Studies

The South African Department of Correctional Services (DCS) has a constitutional mandate to provide rehabilitation programs that address offenders’ criminal conducts. The treatment approach currently used to deliver this mandate is grounded on the Needs-Based Model where dynamic factors associated with recidivism are systematically targeted in treatment of offenders’ criminal behaviors. But the reality of the matter is that there are systemic problems that challenge the DCS both conveying its moral messaging and fulfilling its legal commitment on the rehabilitation of offenders. The DCS mission is far to be accomplished due to its failure to reduce recidivism. Along these lines, …


Decreasing Door-To-Door Times For Infliximab Infusions In A Children's Hospital Observation Unit, Kelly C. Sandberg, Janet N. Lucien, Denise Stoll, Erica Yanney, Adam Mezoff Feb 2019

Decreasing Door-To-Door Times For Infliximab Infusions In A Children's Hospital Observation Unit, Kelly C. Sandberg, Janet N. Lucien, Denise Stoll, Erica Yanney, Adam Mezoff

Pediatrics Faculty Publications

Introduction:

Children with inflammatory bowel disease (IBD) often require infliximab infusions to manage their disease. Infusions administered in the hospital setting require the patient and their families to devote many hours away from home. Changing to a rapid infusion protocol has been shown in the literature to be safe and has the potential to decrease time spent in the hospital receiving infusions.

Methods:

We describe stepwise changes made over a 4-month period to improve infliximab infusion efficiency and lessen the time spent in the hospital by IBD patients and their families. These changes included the implementation of a standardized order …


Purification, Identification, And Sensory Evaluation Of Kokumi Peptides From Agaricus Bisporus Mushroom, Tao Feng, Yang Wu, Zhiwen Zhang, Shiqing Song, Haining Zhuang, Zhimin Xu, Linyun Yao, Min Sun Feb 2019

Purification, Identification, And Sensory Evaluation Of Kokumi Peptides From Agaricus Bisporus Mushroom, Tao Feng, Yang Wu, Zhiwen Zhang, Shiqing Song, Haining Zhuang, Zhimin Xu, Linyun Yao, Min Sun

Faculty Publications

Agaricus bisporus can enhance the umami and salty taste in chicken soup, and also has a high protein content, which indicates that there might be some kokumi taste compounds in this mushroom. Therefore, through ultrafiltration, gel permeation chromatography (GPC), and reverse phase-high performance liquid chromatography (RP-HPLC), some peptides in fresh Agaricus bisporus mushroom were isolated. Then, these peptides were identified by sensory evaluation and ultra performance liquid chromatography (UPLC) coupled quadruple time of flight mass spectrometry (Q-TOF-MS). The sensory evaluation results showed that the addition of aqueous extract isolated from Agaricus bisporus to model chicken broth did enhance chicken broth's …


B Cell Homeostasis Is Maintained During Long-Duration Spaceflight, Guillaume Spielmann, Nadia Agha, Hawley Kunz, Richard J. Simpson, Brian Crucian, Satish Mehta, Mitzi Laughlin, John Campbell Feb 2019

B Cell Homeostasis Is Maintained During Long-Duration Spaceflight, Guillaume Spielmann, Nadia Agha, Hawley Kunz, Richard J. Simpson, Brian Crucian, Satish Mehta, Mitzi Laughlin, John Campbell

Faculty Publications

Long-duration spaceflights reportedly induce immune dysregulation, which is considered a risk to astronaut safety and mission success. Recent studies have examined the impact of spaceflight on markers of adaptive and innate immunity, but no study, to date, has comprehensively evaluated humoral immunity and serological markers of B cell function. The aim of this study was to characterize changes in B cell numbers and phenotypes, along with plasma Igs and polyclonal free light chains (FLCs)—near-“real-time” biomarkers of Ig synthesis—in response to an ~6-mo mission to the International Space Station (ISS). Whole-blood samples were collected before flight, during flight (“Early flight,” “Mid-flight,” …


Phylogenetic History Of The Amy Gene Cluster In Catarrhines, Christian M. Gagnon Feb 2019

Phylogenetic History Of The Amy Gene Cluster In Catarrhines, Christian M. Gagnon

Theses and Dissertations

This study phylogenetically analyzed 30 AMY-related genes from 11 primates. The results show the gradual expansion of the AMY gene family which could have allowed primates to adapt to various ecological landscapes and maximize energy intake from starch-rich foods in periods of food scarcity.


Climatic Variables Are Strong Predictors Of Allonursing And Communal Nesting In Primates, Alexandra Louppova Feb 2019

Climatic Variables Are Strong Predictors Of Allonursing And Communal Nesting In Primates, Alexandra Louppova

Theses and Dissertations

Allomaternal care (AMC) is widespread throughout the primate order, previous studies have focused on benefits and costs to individuals. However, our understanding of environmental impacts on AMC behaviors in primates is still limited. Our study examines how ecology and environmental factors can predict certain AMC behaviors more than others.


A Bite Of The Big Apple: The Anthropology Of Pesticide Use In New York City, Faye O'Brien Feb 2019

A Bite Of The Big Apple: The Anthropology Of Pesticide Use In New York City, Faye O'Brien

Theses and Dissertations

Pesticide exposure in the developing world is well described in anthropology. How pesticide use and exposure is ordered and experienced socially, economically and culturally in Western urban communities is less well studied. The long-term consequences of synergistic pesticide exposure is not easily measurable, which this research addresses through social inquiry.


Culture As Sustainability: The Case Study Of Govardhan Ecovillage And Vedic Culture In India, Danielle Lella Bartolone Feb 2019

Culture As Sustainability: The Case Study Of Govardhan Ecovillage And Vedic Culture In India, Danielle Lella Bartolone

Theses and Dissertations

This project investigates the relationship between sustainability and Vedic culture of India. The ethnographic research at Govardhan Ecovillage seeks to understand how sustainability is embedded in culture. I employ grounded theory for my research methodology which reveals three key themes explaining fundamental and interrelated dimensions of Vedic culture as sustainability.


Object Permanence In Asian Elephants (Elephas Maximus), Dalia Miller Feb 2019

Object Permanence In Asian Elephants (Elephas Maximus), Dalia Miller

Theses and Dissertations

This study investigated object permanence in Asian elephants (Elephas maximus) using visible and invisible test paradigms with single and multiple object displacements. Elephants were predicted to succeed, demonstrating a capacity for object permanence and for using vision in a cognitive task. Study outcomes supported these predictions.