Digital Commons Network^™

Digital Transformation – A Hungarian Overview, Andrea Kő, Péter Fehér, Zoltán Szabó

Economic and Business Review

Digital transformation is considered as an increasingly important process for organizations today, critical for the survival of companies. The spreading of digital technologies throughout our societies brings along various changes in organisational culture, people, business processes and business models. The perception of digital transformation’s importance among the management of companies is lower in some European countries, among others in Hungary. Our research aims to provide an overview of digital transformation in Hungarian companies from the dimensions of strategy, technology and digital innovation capabilities. We discuss the objectives of digital transformation and the role of IT departments in digital transformation. The …

Design And Development Of A Perfusion Bioreactor With Internal Volume Expansion And Cell Retention For Cell And Gene Therapy Manufacturing, Corinna Doris

KGI Theses and Dissertations

Economically producing patient-specific cell therapies at commercial levels remains a challenge as it requires manufacturing separate batches per patient where the production system must be scaled-out rather than scaled-up to supply more patient doses. The resulting high production cost and consequent price-point can limit patient access. Specifically, the current cell expansion processes are highly manual and laborious, with the number and complexity of operations and components increasing the opportunities for failure and contamination. This work therefore aims to design a mechanically simple bioreactor that is better suited for scale-out by consolidating the cell expansion process to fewer components, vessels, and …

Big Ink V. Bigger Tech, Ramsi Woodcock

Law Faculty Popular Media

When in 2011 Paul Krugman attacked the press for bending over backwards to give equal billing to conservative experts on social security, even though the conservatives were plainly wrong, I celebrated. Social security isn’t the biggest part of the government’s budget, and calls to privatize it in order to save the country from bankruptcy were blatant fear mongering. Why should the press report those calls with a neutrality that could mislead readers into thinking the position reasonable?

Journalists’ ethic of balanced reporting looked, at the time, like gross negligence at best, and deceit at worst. But lost in the pathos …

Ryan Miller, Appellant/Petitioner V. Trial Court Brenda Miller, Appellee/Respondent. : Brief Of Appellant, Utah Court Of Appeals

Utah Court of Appeals Briefs (2007– 2019)

Appeal from the Second District Court, Layton, Davis County Judge Michael S. Edwards

Jonathan Hibshman (12552), Marco Brown (13156), Counsel for Appellant/Petitioner

Dustin D. Gibb, Counsel for Appellee/Respondent

Troubling “Technologies”: Exploring The Global Learning Xprize Using The Frameworks Of Skinner And Foucault, Tanya Elias

Current Issues in Emerging eLearning

This work focuses on the question: What might be wrong with large-scale approaches to learning? In posing this question, my purpose is not to suggest that large-scale approaches have no role to play within a complex educational landscape. Rather, I seek to introduce a starting point for more critical and nuanced approaches to achieving proper scale within digital learning, whether big and small. Organized around a series of stories from a train-ride home, I introduce a series of process-based “technologies” as defined by Skinner (1971) and Foucault (1988). After contrasting key concepts of Skinner and Foucault, I apply Foucault’s framework …

Educator Professional Conversations Via Twitter Chat: Speech Acts And Intentions In #Pdbookclub, Suzanne L. Porath

Current Issues in Emerging eLearning

#PDBookChat was an affinity space of educators who read a professional book together and reflected on their learning through blogs, Twitter, and Google+. The book study culminated with an hour-long synchronous Twitter chat. Using Computer-Mediated Discourse Analysis (Herring, 2001) and speech act theory (Searle, 1976) this paper focused on the Twitter chat to examine the discussion among the participants, the specific ways in which they connected their responses to each other and the content of the professional book they read, and provided an analysis of the key themes of the chat. This research provides evidence of how educators use Twitter …

Midlife Suicide: Examination Through An Ecological And Interpersonal Lens, Jayna Bonfini

Electronic Theses and Dissertations

Suicide has increased over the past decade among midlife adults in the United States. It is the fourth leading cause of death among persons aged 35–54 years and the eighth leading cause of death among persons aged 55–64 years. The primary purpose of this hermeneutic phenomenological study is to examine, describe, and understand the lived experiences of midlife adults who have contemplated suicide and who have sought assistance and support from their peers via an online forum for those with an interest in and/or history of suicidality. Bronfenbrenner’s (1977) bioecological model, Joiner’s (2005) interpersonal theory of suicide, and van Manen’s …

Decolonizing American Democracy And The Problem Of Gerrymandering: Implications Of Border Designs From A Communication Ethics Perspective, Mark Gardner

Electronic Theses and Dissertations

This project attempts to understand the powerful force of political borders from a historical and communicative perspective. Of particular importance to this research is the role that political borders play in shaping individuals’ relationship to structures and practices of democracy. Following insights of decolonial and communication ethics scholars, this work understands the importance of ethically framing deliberations surrounding physical, metaphorical, and categorical political borders. Five chapters make up this work in the culmination of analyzing political gerrymandering as a form of democratic competition grounded in the rhetoric of colonialism. Tracing the colonial history of borders throughout American democracy provides this …

A Darker Side Of Venus: An Empirical-Phenomenological Study Of Women's Negative Experiences Encountering Pornographic Imagery, Rebecca Gimeno

Electronic Theses and Dissertations

This empirical-phenomenological study explores the psychological dimensions of negatively encountering a pornographic image. The study includes four participants, all adult women who have had an adverse encounter with a pornographic image within the past five years at the time of the data collection. The recollected experiences of the participants were collected through written narratives as well as semi-structured interviews.

The written narratives and recorded audio interviews were transcribed and subsequently analyzed using an empirical-phenomenological analysis, a process that yielded situated structures. From this analysis, thematic elements of each structure were brought to light. Some of the thematic elements that were …

Bureaucratic Modernity And The Erosion Of Practical Reason: A Rhetorical Education As An Antidote, David Impellizzeri

Electronic Theses and Dissertations

To what extent and in what ways does modernity reveal itself through the bureaucratic? This project aims at an interpretive understanding of bureaucratic modernity. The rationalization of society and action in the (late) modern world requires that an increasing number of human activities and domains be explained in allegedly neutral, ‘rational’ terms and without reference to morally substantive ends. Ultimately, this entails a form of epistemic reductionism that elevates instrumental rationality to the exclusion of practical reason and probabilistic ways of knowing. Bureaucratic modernity signifies a decrease in choices that can be legitimized in public on some basis other …

The Impact Of Retention Efforts On The Collegiate Experience Of Students Of Color At A Predominantly White Institution (Pwi), Jeffrie Mallory

Electronic Theses and Dissertations

This dissertation explored perceptions of thirteen stakeholders who participated in the Minority Orientation Program, a pre-entry initiative focused on retaining students of color at a private, four-year university located in the northeast region of the United States. Situated in Vincent Tinto’s Theory of Student Integration and Critical Race Theory, the author qualitatively assessed the Minority Orientation Program’s impact on participating students of color and the program’s influence on their enrollment through the completion of their Freshman year. The study’s findings confirmed that the Minority Orientation Program affects the collegiate experience for students of color in several ways. Positive influences in …

Nanomedicine-Driven Neuropathic Pain Relief In Rat Model Is Associated With Macrophage Polarity And Mast Cell Activation, Muzamil Saleem

Electronic Theses and Dissertations

We explored the immune neuropathology underlying multi-day relief from neuropathic pain in a rat model initiated at the sciatic nerve by using a nanoemulsion-based nanomedicine as a biological probe. The nanomedicine is theranostic: both therapeutic (containing celecoxib drug) and diagnostic (containing near-infrared fluorescent (NIRF) dye) and is small enough to be phagocytosed by circulating monocytes. A model of neuropathic pain is initiated by tying four 1mm spaced knots around the sciatic nerve with chromic gut suture, which results in neuroinflammation, and a resultant pain-like behavior manifests. We show that pain-like behavior reaches a plateau of maximum hypersensitivity 8 days post-surgery, …

An Exploration Of Communication Ethics Scholarship And Economic Spheres, Andrew Tinker

Electronic Theses and Dissertations

This project examines communication ethics scholarship to understand how economics is understood within the field and to establish coordinates for scholars to discuss economic spheres as phenomena that affect communication ethics. Scholars draw from the tradition of virtue ethics to mark communication ethics inquiry as that which explores the practices that protect and promote the “good.” Philosophers of communication and communication ethicists have developed paradigmatic metaphors for the field that allow us to understand the formation of ethical guidelines within communities both familial, corporate, and national, that promote and protect various goods. These metaphors include “hierarchy” and “sameness” from Charles …

Perceptions Of Blended Learning In The High School Classroom, Kelli Murphy

Electronic Theses and Dissertations

As innovative technologies and accessibility increase in the K12 environment, teachers are offered opportunities to rethink the paradigm of the instructional and learning process. They are at the forefront of instructional change. One type of change is the use of technology as an instructional strategy. Blended learning is a type of instructional strategy which incorporates both online and face-to-face instruction.

The instructional choices a K12 teacher makes under their own volition to present new content in a technology-rich school is the focus of this study. A quantitative research study was performed in a high school with high technology accessibility. Teachers’ …

Females In Stem: Self-Efficacy Within Women Who Pursue Stem Majors, Lori Grata

Electronic Theses and Dissertations

While many efforts have been made within the United States, women are still underrepresented within STEM. Research within this document shows that women and men score similarly on STEM-related standardized tests. The question remains, why are there still large quantities of men outnumbering women in college majors and career fields of STEM? Looking at female STEM self-efficacy and gender role in culture could provide insight to the problem at hand. A survey was given to investigate self-efficacy and students’ STEM backgrounds of undergraduate female students who are currently in a 4-year STEM-related major within one university.

The Art Of Subtitling: A Case Study Of A Chinese Online Fansub Group, Xianwei Wu

Theses - ALL

Online fan subtitling (hereafter fansub) groups are a recent phenomenon that have quickly gained global popularity. They are groups of volunteers who produce and distribute subtitles of English televisions shows and films for free. However, to date not much academic attention has been paid to this phenomenon in a critical capacity, with the exception of anime fansubbing. This study closely examines one fansub group in China using a single-case design case study. The methods of data collection include: in-depth interviews with the translators; participant observation as a subtitle translator; and textual/discourse analysis of the subtitles. This study will use the …

Exploratory Study On Trust, Distrust, And Credibility In Machine Journalism, Stephen Wonchul Song

Dissertations - ALL

The current study investigated the effect of machine-generated journalism. Specifically, the effect of machine journalism compared to human journalist on the perceptions of credibility and distrust for news articles on controversial topics was explored. To further extend the well- established theories of credibility in journalism, this study introduced the concept of distrust as a construct that is distinct from credibility or trust. The relationship between trust and hostile media effect was explored. Finally, this study investigated if trust and hostile media effect are related to the perception of fake news. The results show that distrust was indeed distinct from credibility …

Lonely Game, Kat L. Andersen

LSU New Orleans Theses and Dissertations

Lonely Gameis a collection of short stories exploring different manifestations and consequences of loneliness. Secondary thematic elements include perceptions based on unique life experiences, and how different perspectives play with one’s concept of reality.

Expanding The Definition Of Liminality: Speculative Fiction As An Exploration Of New Boundaries, Dianna C. Lacy

LSU New Orleans Theses and Dissertations

Speculative fiction allows an expanded view of literature and so allows scholars to explore new boundaries in the way words and ideas work. In the titular character of The Last Unicorn by Peter S. Beagle, the reader sees an expansion of self through liminality while A Scanner Darkly by Philip K. Dick explores its collapse. In order to portray each of these the character examined must move though one seems to move upward and the other downward. This idea of movement is only part of what expands the idea of liminality past the traditional idea of a doorway to create …

How To Get A Job In Book Publishing, Grecia Medina

LSU New Orleans Theses and Dissertations

There are many different doorways into the world of book publishing and it can be challenging, but there are choices that can make it easier. Aspiring publishers often have a hard time breaking into this world because they have no guide. This thesis will be a guide to traversing the different avenues into the world of publishing. Prospective publishers, editors, and writers will be provided with a landscape of what it’s like to work in book publishing. It will also cover the two different ways that people become publishers, an overview of the basic requirements that publishing houses look for …

Evolution And Stratigraphic Architecture Of Tidal Point Bars With And Without Fluvial Input: Influence Of Variable Flow Regimes On Sediment And Facies Distribution, And Lateral Accretion, Pricilla Souza

LSU New Orleans Theses and Dissertations

Tide-influenced point bars represent a significant proportion of shallow-marine deposits, commonly developed along meandering channels in most backbarrier and estuarine systems. However, sedimentological studies to characterize this type of deposit are still emerging. They often present very heterogeneous internal architectures which development is controlled by the complex flow patterns operating in tidal environments. The study of the sedimentological and morphological characteristics of these features provides better understanding of the hydrodynamic processes that shape coastal systems and control their evolution as well as it contributes to better reservoir potential prediction and production strategy optimization, as tidal point bars may represent hydrocarbon …

Digital Transformation – The Hype And Conceptual Changes, Luka Tomat, Peter Trkman

Economic and Business Review

Digital transformation (DT) is attracting increased attention; many papers and special issues focus on various aspects of DT. Still, DT often serves solely as a repackaging of previously existing ideas. Our paper argues that the term is over-hyped and has been used to rebrand various fields to attract management attention. However, this alone cannot explain the reasons for such an immense rise in the popularity of the concept. To understand the underlying motives for current DT adoration, our paper aims to identify conceptual changes that have happened in the last decade. These changes have to be considered if companies want …

Learning Together In Public And In Private: Exploring Learner Interactions And Engagement In A Blended-Platform Mooc Environment, Arianna Montero-Colbert, Natalie Delia Deckard, Bonnie Stewart, Sundi Richard, Alexa Nanan

Current Issues in Emerging eLearning

With the growing popularity of connectivist MOOCs, the aim of facilitators has increasingly shifted from helping students meet completion-oriented goals to encouraging meaningful engagement among participants. In this paper, we study the relationship between platform of engagement and learner participation, controlling for relevant demographic factors of participants including gender, age, and level of education attained. Our study employs four distinct measures of participatory engagement: autonomous learning, knowledge reproduction, information networking, and scholarly engagement. We find that on the public platform of Twitter, participants were more likely to exhibit meaningful engagement patterns across all measures studied than they were on the …

Comparative Reflection On Best Known Instructional Design Models: Notes From The Field, Bengi Birgili

Current Issues in Emerging eLearning

This paper is intended to stimulate discussion on historical and evolving instructional design models in an educational era. After enriching the vision of what constitutes an instructional design, the paper explores the historical development and improvement of instructional design processes and models. The instructional design models of Dick and Carey, Morrison, Ross and Kemp, Posner and Rudnitsky, and Smith and Ragan are identified herein as being among the best known, most popular, and most widely applied instructional design models in the field of educational sciences. The philosophical underpinnings and the rationales for the arrangement of components in each instructional design …

Regionalist Social Movements In Contemporary Chile: Production Of Space, Place, Territory, And Scale Through Collective Action, Miguel A. Contreras

Dissertations - ALL

In the last decade, the organization of several territorially based social movements in Chile has expressed a significant level of social discomfort about the political and economic system of the country. The central objective of this dissertation is to analyze how motivations, achievements, and failures of these movements have a dialectical relationship with the spatial features, specifically with the concepts place, territory and scale. Critical geography, political geography, and social movements’ studies provide the theoretical framework for the analysis, highlighting the significance of social movements as producers of collective knowledge. This research used a qualitative approach with a mix-methods design …

Homeostatic Elastic States And The Stability Of Elastic Arteries, Xinyu Zhang

Dissertations - ALL

Vascular mechanics has undergone significant growth within the last 50 years owing to the rapid development of nonlinear continuum mechanics occurring roughly within the same period and motivated primarily by rubber materials. However, one important distinction of blood vessels, in contrast to typical engineering materials is that, through a variety of physiological mechanisms, they seek to maintain constant a preferred mechanical state (mechanical homeostasis) thereby exhibiting a remarkable mechanical stability in response to temporal evolution and alterations in blood pressure, vessel tethering forces and geometry and material properties. The mechanical state experienced by blood vessels plays a critical role in …

Raising An Indoor Generation: Outdoor Environmental Education Impact On Adolescent Development, Daisy Elizabeth Bewley

Student Theses 2015-Present

In an increasingly digital world, children are growing up with less involvement and interaction with the environment. Hands-on and experiential learning is less popular in schools and a more test-oriented and numerical evaluation is increasingly popular. This thesis explores the decrease in outdoor environmental education and the impact that has on adolescent development and developmental milestones in children. This impact extends past just mental development and impacts the physical health development of children. Obesity, attention deficit disorders, and other behavioral issues are just a few of the signs of the problems that have arisen due to a decrease in environmental …

Designing The City, Sustainably: Sustainability And Climate Change Resiliency In New York City, Cosima Balletti-Thomas

Student Theses 2015-Present

Abstract

This paper explores how New York City and especially Manhattan has integrated sustainability into its agenda as a coastal metropolitan nucleus. Secondly, it assesses the New York City’s resiliency strategies that utilize environmental policy and design to confront its vulnerability to changes in the environment on account of global climate change, which has primarily manifested in the Northeastern region in the form of sea level rise, storm surge, and frequent flooding. Chapter 1 uses quantitative climate data from a multitude of sources such as the New York State Department of Environmental Conservation'sreport on the “Impacts of Climate Change …

Charge-Based Optimization Of Neurotensin For Neurotensin-Receptor-1 Targeting Utilizing A One-Bead One-Compound Peptide Library Approach, Trey Neeley

Theses & Dissertations

Neurotensin-receptor-1 (NTSR1) is regularly overexpressed in various cancers and contributes to the proliferation, survival, migration, invasion, and angiogenesis of tumors. NTSR1-targeting vectors have demonstrated promise in both diagnostic and therapeutic aspects. Unfortunately, the relatively poor in vivo metabolic stability and high renal uptake and retention of NTSR1-targeted compounds have hampered the translation to the clinic. In this research, we utilized a one-bead one-compound (OBOC) peptide library approach to make targeted modifications at the naturally charged residues of an NTS (4-13) sequence to discover an NTS derivative with comparable affinity to NTSR1, acceptable in vivo stability, and tolerable renal retention. Subsequent …

The Role Of Histone Chaperone Fact Complex In Base Excision Repair Pathway And Its Therapeutic Potential In Colon Cancer And Medulloblastoma, Heyu Song

Theses & Dissertations

Base excision repair (BER) pathway is required for the removal of damaged bases caused by alkylation, oxidation and ring-saturation. Human apurinic/apyrimidinic endonuclease 1 (APE1) plays a central role in BER pathway. Although repair of damaged bases by recombinant APE1 has been well investigated in vitro, how APE1 gains access to damaged bases in the context of chromatin is largely unknown. A prominent member of the histone chaperone family, FACT (Facilitates Chromatin Transcription) is thought to reorganize nucleosomes through the destabilization of multiple intra-nucleosome contacts. FACT complex is composed of two polypeptides identified as SPT16 (Suppressor of Ty 16) and SSRP1 …