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Stability Through Economic Growth In Afghanistan, Abdul Qadir Khan

Boise State University Theses and Dissertations

This thesis analyzes the Afghan public’s opinion to identify the overall direction of the country, whether the country, in terms of economic growth, is moving in a positive direction or not. How do economic factors affect the public’s views on the direction of the country? Based on that, this study finds that economic growth has an effect on the Afghan public’s opinion on the country’s direction.

Afghans are not enjoying stability in their country yet, after the majority of Afghans accepted U.S. military intervention in 2001 and the establishment of the new government to end instability. It was not an …

Untitled 2 // Untitled 1, Hannah Mccasland

Gandy Dancer Archives

No abstract provided.

Working With Environmental Economists, Annika Marie Rieger, Joerg Rieger

Research Collection School of Social Sciences

Awareness of environmental degradation, culminating in the broad global transformations of human-caused climate change, is no longer a peripheral issue. And while there may be some debate of climate change, a simple denial is no longer an option in light of the data and the agreement of 97 per cent of scientists. In light of the sheer magnitude of the challenge, which has the potential to threaten human survival, much of what we know must be rethought, including traditional academic disciplines. In this essay, an environmental sociologist and a theologian enter into a conversation with environmental economists and others concerned …

Pornographic Deepfakes: The Case For Federal Criminalization Of Revenge Porn’S Next Tragic Act, Rebecca A. Delfino

Fordham Law Review

This could happen to you. Like millions of people worldwide, you have uploaded digital photographs of yourself to the internet through social media platforms. Your pictures aren’t sexually explicit or revealing—they depict your daily life, spending time with friends or taking “selfies” on vacation. But then someone decides they don’t like you. Using an app available on any smartphone, this antagonist clips digital images of your face from your innocuous pictures and pastes them seamlessly onto the body of a person engaged in sexually explicit acts. Without your knowledge or consent, you become the “star” of a realistic, pornographic “deepfake.” …

“Armed And Dangerous” A Half Century Later: Today’S Gun Rights Should Impact Terry’S Framework, Alexander Butwin

Fordham Law Review

Over fifty years ago, in Terry v. Ohio, the U.S. Supreme Court established a two-part framework in which police officers may, without a warrant, stop and search an individual for weapons without violating the Fourth Amendment’s protections against unreasonable searches and seizures. Officers must (1) suspect that criminal activity has occurred, or will soon occur, and (2) have a reasonable fear that the individual is “armed” and poses a threat to the responding officers or to others—i.e., “dangerous.” The second prong’s exact meaning is disputed and has created a split among the circuits as to whether merely being “armed” …

Effects Of Mercury On The Dopamine Transporter Cell Surface Expression In Pc12 Cells, Christina Hui

Student Theses

Environmental factors, such as heavy metal exposures, have been suggested to have an impact not only on neurodegenerative disease, such as Parkinson’s disease, but also on psychostimulants abuse and their toxicity. In this study, two questions were addressed: 1) effects of mercuric chloride on parkinsonian toxicant 1-methyl-4-phenylpyridinium (MPP⁺) induced cytotoxicity and 2) effects of mercuric chloride on cell surface dopamine transporter. Pheochromocytorma cells (PC12) were treated with various concentrations of mercuric chloride (0.02~2.0 ppm) for 4 hours with and without 0.1 mM MPP⁺. Significant potentiation of toxicity was observed when there was co-treatment with 0.5 ppm …

Protecting Health Information In Utero: A Radical Proposal, Luke Isaac Haqq

Journal of Law and Policy

This Article introduces an underappreciated space in which protected health information (“PHI”) remains largely unprotected, a fact that will become only more problematic as clinical medicine increasingly turns to genomics. The past decade has seen significant advances in the prevention of birth defects, especially with the introduction of clinical preconception, prenatal, and neonatal genomic sequencing. Parental access to the results of embryonic and fetal clinical sequencing is critical to reproductive autonomy; results can provide parents with important considerations in determining whether to seek or avoid conception, as well as in deciding whether to carry a pregnancy to term. The information …

Uncovering The Zeb1 Interactome To Identify Novel Regulators Of Metastatic Non-Small Cell Lung Cancer, Roxsan Manshouri

Dissertations and Theses (Open Access)

Non-small cell lung cancer (NSCLC) is the leading cause of cancer-related death in the United States, due in part to the robust affinity of lung cancer cells to metastasize. Understanding the processes that contribute to metastasis provides promise for the discovery of novel therapeutic targets. Epithelial-tomesenchymal transition (EMT) is a proposed model for the initiation of metastasis. During EMT cell adhesion and polarity is reduced, allowing epithelial cancer cells to dissociate from the primary tumor and invade distant organs. The transcription factor zinc finger E-box-binding homeobox 1 (ZEB1) has been reported to uniquely correlate with NSCLC disease progression and to …

The Role Of Membrane Domains In Protein And Lipid Sorting During Endocytic Traffic, Blanca B. Diaz-Rohrer

Dissertations and Theses (Open Access)

The lipid and protein composition of the plasma membrane (PM) must be tightly controlled to maintain cellular functionality, despite constant, rapid endocytosis. Because de novo synthesis of proteins and lipids is energetically costly, the cell depends on active recycling to return endocytosed membrane components back to the PM. For most proteins, the mechanisms and pathways of their PM retention remain unknown. The work presented here shows that association with ordered membrane microdomains is fully sufficient for PM recycling and that abrogation of raft partitioning leads to their degradation in lysosomes. These findings support a model wherein ordered membrane domains mediate …

Identification And Molecular Analysis Of Dna In Exosomes, Jena Tavormina

Dissertations and Theses (Open Access)

Exosomes are heterogeneous nanoparticles 50-150nm in diameter. Exosomes contain many functional cargo components, such as protein, DNA, and RNA. While protein and RNA exosome content has been extensively studied, very little work has been done to characterize exosomal DNA. Here, we demonstrate that exosomal DNA is heterogeneous and its packaging into exosomes is dependent on the cell of origin. Furthermore, through a rigorous assessment of various isolation methods, we identify Size Exclusion Chromatography (SEC) as the best method for the isolation of exosomal DNA for downstream applications. Additionally, we evaluate the methylation status of exosomal DNA and demonstrate that exosomal …

Assessment Of New Innovations In Pet/Ct For Respiratory Motion Correction, Joseph Meier

Dissertations and Theses (Open Access)

In oncological imaging, Positron Emission Tomography/Computed Tomography (PET/CT) is a vital tool used for stating and treatment response assessment of patients due to its ability to visualize and accurately quantify the bio-distribution of radiolabeled pharmaceuticals. However, due to the long acquisition times, respiratory motion blur is unavoidable in PET images especially in the lower lung and upper abdomen. This leads to reductions in measured radiotracer concentration and lesion detectability all of which can potentially result in incorrect management of patients. Multiple methods exist to correct for respiratory motion but are rarely used in the routine clinical setting because of: 1) …

Relevance Of Fgfr1 And Its Isoforms In Prostate Cancer Bone Metastases, Estefania Labanca

Dissertations and Theses (Open Access)

The fibroblast growth factor receptor (FGFR) 1 is implicated in prostate cancer (PCa) progression. Various FGFR1 isoforms have been described and we demonstrate here that the well-characterized FGFR1 a and b isoforms are correlated with the expression of different genes and pathways in human PCa. Direct injection of PC3 PCa cells overexpressing FGFR1 isoforms into the femur of mice resulted in enhanced tumor growth and reduction in bone volume when compared with PC3 expressing empty vector. However, only PC3 overexpressing FGFR1 b was associated with increased osteoclast parameters, suggesting that each isoform may mediate diverse biological effects (similar findings were …

The Long Road Back To Skokie: Returning The First Amendment To Mask Wearers, Rob Kahn

Journal of Law and Policy

When the Seventh Circuit upheld the First Amendment right of Nazis to march in Skokie, Illinois in 1978, the protection of mask wearers was not far behind. Since then, doctrinal paths have diverged. While the Supreme Court continues to protect hate speech, mask wearing has been increasingly placed outside First Amendment protection. This article seeks to get to the bottom of this doctrinal divergence by addressing the symbolic purposes of mask bans—rooted in repudiating the Ku Klux Klan—as well as the doctrinal steps taken over the past forty years to restrict the First Amendment claims of mask wearers. It also …

Increasing Lapses In Data Security: The Need For A Common Answer To What Constitutes Standing In A Data Breach Context, Aaron Benjamin Edelman

Journal of Law and Policy

As the number of data breaches continues to rise in the United States, so does the amount of data breach litigation. Many potential plaintiffs who suffered as victims of data breaches, however, find themselves in limbo regarding the issue of standing before a court because of a significant split on standing determinations amongst the federal circuit courts. Thus, while victims of data breaches oftentimes have their personal information fall into the hands of nefarious characters who intend to use the information to a victim’s detriment, that may not be enough to provide victims a right to sue in federal court …

Shoring Up The Hear Act: Proposed Amendments To Federal Legislation Designed To Assist Heirs And Claimants Of Nazi-Looted Art, Alexander Hull

Journal of Law and Policy

From 1933 to 1945, Nazi German forces executed a mass campaign of property confiscation, stealing as many as 600,000 pieces of art, including paintings, tapestries and sculptures from museums and private collections across Europe. It is estimated that some 300,000 pieces of art are still missing or are currently in the possession of someone other than the so-called “true” owner, based on reviews of Nazi documentation conducted by the Jewish Restitution Organization. While Nazi art looting has been regarded as “dehumanizing,” “self-advancing” and concomitant with the Nazi regime’s larger genocidal crusade, restitution in this context has been framed as a …

Inflammation And Corrosion In Total Hip Prostheses: The Generation And Interaction Of Reactive Oxygen Species With Cocrmo Metallic Biomaterial Surfaces, Michael John Wiegand

All Dissertations

There are many molecules, species and mechanisms that contribute to the overall wear and degradation of biometallic alloys like cobalt-chromium-molybdenum (CoCrMo). Following implantation, orthopaedic alloys are subject to an encompassing inflammatory response that will either lead to foreign body giant cell formation and attachment to the surface or the fibrous tissue encapsulation, forming an inflamed periprosthetic joint. In addition to the inflammatory response, tribocorrosion-based processes of alloy-on-alloy or alloy-on-polymer couples release polymeric wear debris, oxides, hydroxides, and metal ions in response to excessive wear, loading and corrosion. It is hypothesized that these processes, biological and triboelectrochemical, are linked together in …

Role Of Cryptococcus Neoformans Pyruvate Decarboxylase And Aldehyde Dehydrogenase Enzymes In Acetate Production And Virulence, Mufida Ahmed Nagi Ammar

All Dissertations

The basidiomycete Cryptococcus neoformans is is an invasive opportunistic pathogen of the central nervous system and the most frequent cause of fungal meningitis. C. neoformans enters the host by inhalation and protects itself from immune assault in the lungs by producing hydrolytic enzymes, immunosuppressants, and other virulence factors. C. neoformans also adapts to the environment inside the host, including producing metabolites that may confer survival advantages. One of these, acetate, can be kept in reserve as a carbon source or can be used to weaken the immune response by lowering local pH or as a key part of immunomodulatory molecules. …

The Effects Of Indirubin Derivative E804 On Inflammatory Profiles In Glioblastoma Multiforme Cell Lines And Subsequent Crosstalk Effect On Tumor Associated Thp-1 Macrophages, Micaela Ro Scobie

All Dissertations

Glioblastoma Multiforme (GBM) is a highly invasive brain tumor that affects approximately 18,000 people annually in the USA alone yet remains without curative treatment. Median survival with treatment is 14 months, with most treatments only prolonging life for several months while causing severe adverse side effects. There is a need for new therapeutic modalities. Herein I explore two small molecules that show promise in modulating inflammatory signaling in an in vitro GBM model. Indirubins E804 (indirubin-3’-(2,3 dihydroxypropyl)-oximether) and 7BIO (7-Bromoindirubin-3’-oxime) are synthetic derivatives of natural indirubin. Natural indirubin is a bisindole alkaloid derived from tryptophan precursors and is an agonist …

Stability And Toxicity Of Cerium Oxide Nanoparticles In Water-Soil-Plant Systems, Linlin Mu

All Dissertations

Cerium oxide nanoparticles (CeO2 NPs) are being increasingly used in industrial and consumer products and the release of CeO2 NPs into the air, water, and soil is an inevitable consequence. Once released into the environment, CeO2 NPs can have adverse impacts on the environment and human health. Thus, characterizing the environmental behavior and toxic effects of CeO2 NPs is important to protect the environment and human health. To assure such protection, the stability and phytotoxicity of CeO2 NPs need to be known because they are key to understanding their transport, toxicity and bioavailability in water and soil. The objective of …

Design And Evaluation Of Flow Mapping Systems For Heterogeneous Wireless Networks, Jianwei Liu

All Dissertations

Mobile wireless networks are always challenged by growing application demand. The increasing heterogeneity of both mobile device connection capability and wireless network coverage forms a general heterogeneous wireless network (HetNet). This type of HetNet contains sub-networks of different Radio Access Technologies. How to better coordinate the mappings of flows between Access Points (AP) and User Equipment (UE) inside this type of HetNet to improve system and user-level performance is an interesting research problem. The flow mapping systems used by off-the-shelf mobile devices make policy-based decisions from local information. Several global information based flow mapping systems that use Generalized Proportional Fairness …

Modeling Of Household Evacuation Decision, Departure Timing, And Number Of Evacuating Vehicles From Hurricane Matthew, Roa'a Jaber Mohammad Alawadi

All Dissertations

This dissertation investigates households’ evacuation decision, number of household vehicles used in evacuation, and departure timing from Hurricane Matthew. Regarding the evacuation decision, this dissertation takes a step further by presenting three level evacuation decision models that include full, partial, and no evacuation alternatives rather than the binary evacuate/stay decision. Multinomial (MNL) regression and random parameter MNL techniques were utilized to develop the prediction models. Results showed that some of the variables which affect the evacuate/stay decision have different influences on the three alternatives. The preferred MNL model was tested for random parameters and one random parameter (age of the …

Using Activity Based Costing To Inform Resource Allocation, Alexander Mccafferty

All Dissertations

This study identified the effect of variables as measured by activity-based costing (ABC) on course and department margins through the lens of inconsistent rewards. Data were gathered from an ABC initiative conducted at a large public research university in the United States. The data included measurements from 4,421 courses across 57 academic departments. Significant multicollinearity was discovered in the initial analysis, and ultimately half of the variables measured in the ABC initiative were removed. Hierarchical linear modeling (HLM) analyses were run to measure the effect of two latent variables comprised of the remaining variables on course and department margins.

The …

Lived Experiences Of Christian Development Workers In The Thailand Anti-Trafficking Movement: Lessons From The Field, Lauren M. Pinkston

All Dissertations

Private enterprise, sex tourism, international adoption, and soldier recruitment have all been industries that benefit from the coercion or trade of human beings. Although international development organizations and government agencies have been particularly focused on preventing human rights violations, the Protestant Christian community also has been poised with a vested interest around the globe. Unfortunately, data are lacking about faith-based efforts in the anti-trafficking space. This research looks at faith-based organizations’ anti-trafficking operations in Thailand particular, as it has been traditionally known as a nation with unique immigration challenges and extensive migration patterns.

This qualitative study is based on open-ended …

Social Competence And Attitude Towards School In Relation To Academic Achievements Of Students In Kosovo, Blerta Perolli Shehu

All Dissertations

The focus of the research was to determine the relationship among social competence, attitudes toward school and academic achievement of primary school students in Kosovo. Participants in the study were 206 students of 4th grade classes from five different schools in Kosovo, one of their parents and teachers. Parents completed a Survey of Students’ Characteristics, children completed a self-report measure on School Attitude, and teachers completed the Social Competency Rating Form and the School Attitude/Behavior Teacher Version for each of the children in their class. Teachers also assessed the children’s academic performance in 7-items Likert-type scale for each of the …

Development Of Functionalized Capillary-Channeled Polymer (C-Cp) Fibers As Stationary Phase For Affinity Chromatography, Hung Khiem Trang

All Dissertations

At the heart of the chromatography technique, the stationary phase is the essential component that dictates multiple aspects of the separation process. Diverse chemistry of the stationary phases, in combination with the choice of appropriate base support materials, allows chromatography to be used in a wide range of applications ranging from the high-performance separations of trace analytes in complex biological samples for chemical detection and quantification to the large-scale purification of a recombinant protein from a complex media. Traditional chromatographic stationary phases mostly utilize porous materials for the high surface area and versatility for chemical modification. However, in many cases, …

El Leñador, December 2019, El Leñador Staff

El Leñador Newspaper

El Leñador is an English and Spanish newspaper produced by Humboldt State University students. Our staff cover and provide news to Latinx and other diverse communities on campus and in Humboldt County. We are committed to providing relevant news and expanding the representations and stories told about people of color and other marginalized groups. Our work helps create more social, political and cultural diversity in local media.

El Leñador es un periodico en español y inglés producido por estudiantes de la Universidad Estatal de Humboldt. Nuestro personal cubre y provee noticias a la comunidad Latinx y otras comunidades diversas en …

Contributions Of Role-Playing Games: Advantages Of Incorporating Social Media In Disaster Response, Erin Mullin

Graduate Theses and Dissertations

After a disaster, emergency managers need to know who needs help, what type of help they need, and how soon they need it. Traditionally, they have relied on 911 calls and ground assessments to collect this information. Because the needs of a population are not able to be identified in a timely manner by ground assessments and because individuals are often unable to get through to 911, many civilians in distress turn to social media outlets as a last-ditch effort to obtain the services they need. Due to the uncertainty concerning the accuracy of social media posts, responding to disaster …

A Text Mining Analysis Of Central Bank Monetary Policy Communication In Nigeria, Mohammed M, Tumala, Babatunde S. Omotosho

CBN Journal of Applied Statistics (JAS)

This paper employs text-mining techniques to analyse the communication strategy of the Central Bank of Nigeria (CBN) during the period 20042019. Since the policy communique released after each meeting of the CBN’s monetary policy committee (MPC) represents an important tool of central bank communication, we construct a corpus based on 87 policy communiques with a total of 123, 353 words. Having processed the textual data into a form suitable for analysis, we examined the readability, sentiments, and topics of the policy documents. While the CBN’s communication has increased substantially over the years, implying increased monetary policy transparency; the computed Coleman …

Black Fatherhood In America Through The Lens Of Contemporary Memoir, Christian Allred

Criterion: A Journal of Literary Criticism

No abstract provided.

The Gothic And The Gross: Frankenstein And His Friend's Attractiveness To Children, Rebecca Mckee

Criterion: A Journal of Literary Criticism

No abstract provided.