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Limitation Of Rights As A Manifestation Of Duties And Responsibilities Pertaining To The Freedom Expression In Digital Communications, Edmon Makarim, Muhammad Ibrahim Brata, Nabilla Arsyafira
Limitation Of Rights As A Manifestation Of Duties And Responsibilities Pertaining To The Freedom Expression In Digital Communications, Edmon Makarim, Muhammad Ibrahim Brata, Nabilla Arsyafira
Indonesia Law Review
The freedom of expression is thriving due to the global use of the internet. The digital era has revolutionized the scope, practices, and even the definition of freedom expression. However, it also evokes a number of social concerns. Offenses such as the circulation of defamation, hate speech, misleading propaganda to the masses, and fraud, for instance, can be found in the internet. Certain limitations deriving from the conditions prescribed by the human rights principles and instruments as well as the national constitution are therefore prudent to prevent the excess of freedom. As a state that abides to the rule of …
The 1958 New York Convention In Indonesia: History And Commentaries Beyond Monism-Dualism, John Lumbantobing
The 1958 New York Convention In Indonesia: History And Commentaries Beyond Monism-Dualism, John Lumbantobing
Indonesia Law Review
This Article recounts a complete history of Indonesia’s implementation of the 1958 NY Convention. In particular, the elaboration and analysis focus on the comparison between related provisions in the 1999 Indonesian Arbitration Law and the Convention’s provisions as well as on several key Indonesian court decisions on enforcement of foreign arbitral awards. Different than other writings in this area, this Article looks more closely at the practical issues which affect the way Indonesian courts apply or interpret the 1958 NY Convention, such as procedural hurdle and the judicial capacity to comprehend and understand basic concepts and principles of arbitration. The …
Knowledge, Mechanical Aptitude, And Age On Dual-Expertise Teacher Competence: A Correlational Study, Nanang Eko Saputro, Purnomo Purnomo, Tuwoso Tuwoso
Knowledge, Mechanical Aptitude, And Age On Dual-Expertise Teacher Competence: A Correlational Study, Nanang Eko Saputro, Purnomo Purnomo, Tuwoso Tuwoso
Jurnal Pendidikan Sains
The present study aimed to investigate relations of prior knowledge, mechanical aptitude, and age to competence of dual-expertise teachers. The study was conducted following a research design of ex-post facto. The samples were 102 dual-expertise teachers. To answer its problems, the study collected the data by using questionnaires, tests, and documentation. The data gathered were then analyzed employing desctiptive analysis, regression analysis, and partial correlation analysis. The study found that (1) there is a relation between the prior knowledge, mechanical aptitude, and age to the competence of dual-expertise teachers; (2) a relation is revealed between the prior knowledge and the …
Ercore Learning Model In Improving Students’ Critical Thinking Skills, Mustaqim Mustaqim, Aloysius Duran Corebima, Susriyati Mahanal
Ercore Learning Model In Improving Students’ Critical Thinking Skills, Mustaqim Mustaqim, Aloysius Duran Corebima, Susriyati Mahanal
Jurnal Pendidikan Sains
Critical thinking skill is a skill in organizing and generating ideas, interpreting, analyzing, evaluating, and knowledge inference based on evidence, concept, criteria, methodology, or contextual consideration. Students’ critical thinking skill are still low and need to be improved. Critical thinking skill can be developed through student-centered learning. One of the learning models that can be used is ERCoRe learning model. This research aims to know the influence of ERCoRe learning model toward students’ critical thinking skill. The design of this research was quasi-experimental, conducted on senior high school students class. The data analysis that used was covariant. The conclusion based …
Learning Difficulties Of High School Students In Understanding The Material Of Human Reproductive Systems Triggering Misconceptions, Naning Wahyuni, Hadi Suwono, Umie Lestari
Learning Difficulties Of High School Students In Understanding The Material Of Human Reproductive Systems Triggering Misconceptions, Naning Wahyuni, Hadi Suwono, Umie Lestari
Jurnal Pendidikan Sains
Human Reproductive System is a basic concept in biological sciences that is related to daily life and interesting for high school students. Complicated learning materials make it difficult for students to construct their knowledge and understand the concepts. Survey research using a questionnaire was conducted to determine the causes of difficulties for high school students in understanding the Human Reproductive System concepts. Respondents were grade XII science students and two teachers. The data obtained were analyzed descriptively. The research findings indicate that students’ difficulties are due to (1) the extensive usage of scientific terms, (2) abstract concepts, (3) monotone, and …
Sustainability Practices In Higher Education: Stakeholder Engagement In Promoting Campus Sustainability, Maria Assunta C. Cuyegkeng, Abigal Marie T. Favis
Sustainability Practices In Higher Education: Stakeholder Engagement In Promoting Campus Sustainability, Maria Assunta C. Cuyegkeng, Abigal Marie T. Favis
Journal of Management for Global Sustainability
Universities have a role in changing mindsets toward sustainable development through education, research, and extension work. Despite the ongoing trend in favor of sustainability initiatives, however, they themselves struggle to transform organizational practices in their own contexts, especially when trying to get the administration’s buy-in and establish stakeholder engagement. Ateneo de Manila University in particular used its response to the decrees of General Congregation 35 (Society of Jesus, 2008) of the Society of Jesus to serve as the foundation of its campus sustainability programs, especially with respect to its translation into policies that affect the university’s ecological footprint and stakeholder …
Global Collaborative Advantage: Efforts Toward Decolonization Of Business Ethics And Management Scholarship, Jessica Ludescher Imanaka
Global Collaborative Advantage: Efforts Toward Decolonization Of Business Ethics And Management Scholarship, Jessica Ludescher Imanaka
Journal of Management for Global Sustainability
The current trend of prescribing and enforcing ethical business constructs, models, and frameworks developed in and by the Global North has become a new form of paternalistic colonizing of the Global South. Such behavior dangerously mirrors historically oppressive movements through colonization and continues extractive and damaging practices. Indeed, the enforcement of Northern constructs, models, and frameworks facilitates the maintenance of an artificial global hierarchy which continues to harm the South to the North’s benefit. They overlook and prohibit any possible inclusion of ethical and philosophical frameworks derived from the wisdoms and traditions of the South. This article advances the goal …
Effect Of In-Vitro Alpha Lipoic Acid Addition On Spermatozoa Motility In Sperm Preparation Process, Gede Wira Buanayuda, Hamdani Lunardhi, Indra Gusti Mansur
Effect Of In-Vitro Alpha Lipoic Acid Addition On Spermatozoa Motility In Sperm Preparation Process, Gede Wira Buanayuda, Hamdani Lunardhi, Indra Gusti Mansur
Folia Medica Indonesiana
Infertility is a problem for husband and wife, in the last 20 years the number of infertile couples has tended to increase by around 6.5 million pairs. The infertile couple can use the intrauterine insemination method to obtain offspring if a conventional method approach cannot be performed. Insemination requires a sperm preparation stage in which there are centrifugation and resuspension procedures that tend to produce excess reactive oxygen species (ROS). Excessive ROS will damage the motility of the spermatozoa. This study aims to prove the addition of alpha lipoic acid (ALA) as an antioxidant in the process of sperm preparation …
The Effect Of Cinnamomum Burmannii Water Extraction Against Staphylococcus Aureus, Enterobacter Spp., Pseudomonas Aeruginosa, And Candida Albicans: In Vitro Study, Bernadette Dian Novita, Silvia Sutandhio
The Effect Of Cinnamomum Burmannii Water Extraction Against Staphylococcus Aureus, Enterobacter Spp., Pseudomonas Aeruginosa, And Candida Albicans: In Vitro Study, Bernadette Dian Novita, Silvia Sutandhio
Folia Medica Indonesiana
High-intensity exercise (3000-meter runner) contributes to muscle fatigue. Fatigue can be determined by measuring blood lactate levels. Blood lactate levels are a product of anaerobic metabolism. Lactate accumulation due to anaerobic physical activity can inhibit the glycolytic enzyme that affects decreased ATP production, damage of the calcium and sodium pumps in the muscles and causes fatigue. This study aimed to analyze the effect of vitamin E on the level of fatigue through the response of blood lactate levels in the runner 3000 meters. This research was a quasi-experimental research with a pretest-posttest design. Research subjects were 9 volunteer athletes (3000 …
Case Report: The Role Of Intravascular Ultrasonography In Patients Underwent Percutaneous Coronary Intervention, Yudi Her Oktaviono, Alisia Yuana Putri
Case Report: The Role Of Intravascular Ultrasonography In Patients Underwent Percutaneous Coronary Intervention, Yudi Her Oktaviono, Alisia Yuana Putri
Folia Medica Indonesiana
Resveratrol is an antioxidant that can be used as anti-aging. Topical use has several problems because solubility in water is low and unstable to light. This study aimed to evaluate the effect of the combination of soy bean oil and oleic acid liquid lipids on the characteristics, penetration, and stability of resveratrol nanostructured lipid carriers (NLC). Nanostructured lipid carriers (NLC) were made with high shear homogeneous technique. To determine the characterization of NLC, diffraction scanning calorimetry, X-ray diffraction, and Fourier transforms infrared spectrophotometry were used. Examination of the morphological form was carried out with a transmission electron microscope. The particle …
Does Fintech Matter For Indonesia's Economic Growth?, Seema Wati Narayan
Does Fintech Matter For Indonesia's Economic Growth?, Seema Wati Narayan
Bulletin of Monetary Economics and Banking
This paper investigates the role of financial technology (FinTech) in propelling economic growth in Indonesia from 1998 to 2018. The FinTech industry employs a technology-based business model to provide financial services, including lending, payment, investment, and financing services. The study is motivated by endogenous growth theory, which seeks to explain technology as the most important driver of economic growth. The study finds that FinTech startups are positively correlated with Indonesia’s economic growth. FinTech firms in their first year are found to be disruptive, but they fail to have serious consequences on Indonesia’s economic growth; however, they seem to significantly encourage …
Applying Positive Language In Mindful Parenting: A Means Of Building Positive Character In Children, Amrina Rosyada, Agustina Ramadhianti
Applying Positive Language In Mindful Parenting: A Means Of Building Positive Character In Children, Amrina Rosyada, Agustina Ramadhianti
ASEAN Journal of Community Engagement
Positive language is a crucial communication tool, both within the family environment and in external circumstances. Previous research endeavors have evidenced that the inculcation of positive language by parents is effective in building positive character in their children. Thus, language is not merely a communication tool; it is also a means of personality development. However, this application cannot be realized if parents are unaware. Therefore, the community service activity proposed in this paper aims to broaden and strengthen mindful parenting, and to enhance the discernment of positive language in parents to help them build positive character in their children. To …
Teaching Arabic In The Era Of Industrial Revolution 4.0 In Indonesia: Challenges And Opportunities, Azkia Muharom Albantani, Ahmad Madkur
Teaching Arabic In The Era Of Industrial Revolution 4.0 In Indonesia: Challenges And Opportunities, Azkia Muharom Albantani, Ahmad Madkur
ASEAN Journal of Community Engagement
Teaching Arabic as a foreign language (TAFL) in Indonesia has been interest of many scholars, but studies on TAFL in the context of industrial revolution (IR) 4.0 have been rarely conducted. This qualitative study was aimed at investigating the challenges and opportunities in accelerating the quality of Arabic language instruction in the IR 4.0 era. Qualitative data analysis consisting of four steps, namely, data collection, data reduction, data presentation, and data verification was applied to analyze the gathered data. According to the research results, the challenges are the following: Arabic language teachers’ limited adaptation to technology, students’ low motivation to …
Psychoeducation “Aku Peduli” For Parent With Typically Developing Children At An Inclusive Kindergarten, Andi Nur Zamzam Arman, Farida Kurniawati
Psychoeducation “Aku Peduli” For Parent With Typically Developing Children At An Inclusive Kindergarten, Andi Nur Zamzam Arman, Farida Kurniawati
ASEAN Journal of Community Engagement
This study examined the effectiveness of “AKU PEDULI” psychoeducation in helping the parents of typically developing children to increase their knowledge of special needs children and inclusive education at an inclusive kindergarten. “AKU PEDULI” is abbreviated from Anak Berkebutuhan Khusus dan Pendidikan Inklusif (Special Needs Children & Inclusive Education). Quantitative methods were used in both the pre-test and post-test parts of the research. Six mothers aged 28–34 years, of typically developing children were selected to participate in the study through accidental sampling. Participants were required to be parents of typically developing children who attend an inclusive kindergarten and who have …
Diskurso Ng Pagsusulatan Ng Dalawang Binibining Urbana At Felisa, Maria Fe G. Hicana
Diskurso Ng Pagsusulatan Ng Dalawang Binibining Urbana At Felisa, Maria Fe G. Hicana
Malay Journal
Layunin ng pag-aaral na ito na maitampok ang diskurso ng pagsusulatan ng magkapatid na Urbana at Felisa sa deskriptibong pamamaraan. Sa ika-18 siglo naisulat ang akda kaya hindi mapapasubalian ang kalaliman ng pananagalog na ginamit na midyum sa pagsusulatan ng liham ng magkapatid na nasa magkaibang lugar: si Urbana ay nasa Maynila tulad ng ibinabadya ng kaniyang pangalang buhat sa “urban” at si Felisa naman ay nasa probinsiya na ang pangalan naman ay nangangahulugang “kasiyahan.” Inilatag sa pag-aaral na ginamit na midyum ang pagpapalitan ng liham ng magkapatid upang maghatid ng mga aral at kagandahang-asal na sinusunod at ipinasusunod alinsunod …
A Cacophony Of Speech, Law, And Persona: Battling Against The Vortex Of #Metoo In France And The U.S., Anne Wagner, Sarah Marusek
A Cacophony Of Speech, Law, And Persona: Battling Against The Vortex Of #Metoo In France And The U.S., Anne Wagner, Sarah Marusek
Journal of Civil Law Studies
The pervasive proliferation of rumors, through #MeToo and #BalanceTonPorc, communicates meaningful and meaningless-making processes on misconducts both in the French and U.S. con-texts. Such rumors have transformed the online practices by culti-vating both verbal and non-verbal hate speech free and/or free speech. This cacophony of speech, law, and persona has led to a debate relayed on social media platforms, exposing people to a dan-ger zone mostly based as shame, hate, fear, or even destruction, as anonymity and due process no longer prevail.
Internet Screen Time And Related Factors: Threat To Adolescence In Indonesia, Kristiana Kurniasanti, Karina Firdaus, Hans Christian, Tjhin Wiguna, Martina Wiwie, Raden Ismail
Internet Screen Time And Related Factors: Threat To Adolescence In Indonesia, Kristiana Kurniasanti, Karina Firdaus, Hans Christian, Tjhin Wiguna, Martina Wiwie, Raden Ismail
Makara Human Behavior Studies in Asia
The widespread use of the internet has produced both positive and negative impacts. Among the latter is internet addiction (IA). The worldwide prevalence of this addiction has been measured at approximately 6%, although the specific prevalence in Indonesia is uncertain because no validated instrument to measure IA has been developed for the Indonesian context. Hence, screen time was used in this study as an alternative measure of the magnitude of IA in Indonesia, where more than 6 hours is considered risk for IA. Researchers measured internet screen time (IST) and potential related factors in adolescents. The subjects of this cross-sectional …
Analisis Pelaksanaan Perkuliahan Sph Ii Untuk Buku Ajar Perkembangan Embrio Mamalia, Ulya Ruwaida, Mohamad Amin, Umie Lestari
Analisis Pelaksanaan Perkuliahan Sph Ii Untuk Buku Ajar Perkembangan Embrio Mamalia, Ulya Ruwaida, Mohamad Amin, Umie Lestari
Jurnal Pendidikan: Teori, Penelitian, dan Pengembangan
This study aims to identify the need for the development of SPH II teaching materials on mammalian embryo development material. Data collection research was conducted using student questionnaire sheets. The results of the study show that 100% of students need the development of new teaching materials with research results that present applicative examples in society. As many as 57% of students stated difficulties in using available teaching materials because of the complexity of the language and the absence of evaluation. Mammalian embryo development is an elusive material (43%) and there has never been an explanation of the role of genes …
Buku Ajar Ekologi Komunitas Flora Savana Bekol Taman Nasional Baluran Berbasis Problem Based Learning Untuk Matakuliah Ekologi, Nizar Azizatun Nikmah, Fatchur Rohman, Suhadi Suhadi
Buku Ajar Ekologi Komunitas Flora Savana Bekol Taman Nasional Baluran Berbasis Problem Based Learning Untuk Matakuliah Ekologi, Nizar Azizatun Nikmah, Fatchur Rohman, Suhadi Suhadi
Jurnal Pendidikan: Teori, Penelitian, dan Pengembangan
Textbooks are one of the printed materials, arranged efficiently and effectively to support condusive learning in a particular subject. The aim of this research & development’s to produce the effective, valid and practical ecology textbooks based on Problem Based Learning. This textbook for ecology subject, refers to the ADDIE development model. The validation results from the three experts showed very positive results, from the subject expert obtained score are 98,33 (very valid); 100 (very valid) score of subject practitioner; score of 98,75 (very valid) from media expert. Based on the result, this product’s very propered and can be used in …
Pengembangan Modul Menulis Puisi Lingkungan Menggunakan Strategi 5m, Eka Yuni Agustin, Muakibatul Hasanah, Taufik Dermawan
Pengembangan Modul Menulis Puisi Lingkungan Menggunakan Strategi 5m, Eka Yuni Agustin, Muakibatul Hasanah, Taufik Dermawan
Jurnal Pendidikan: Teori, Penelitian, dan Pengembangan
Writing poetry is a skill that is considered difficult because it requires practice to write. The reason is because of the lack of learning that leads to the practice of writing poetry in the classroom with the help of adequate teaching materials. The need for teaching materials in the form of modules and appropriate learning strategies to help students learn independently practice writing poetry. The innovative module presents a variety of material so students get new knowledge through the presentation of material in the module. The addition of environmental insights can also provide new knowledge about the importance of maintaining, …
Potensi Model Inkuiri Terbimbing Dipadu Edutainment Terhadap Penguasaan Konsep Siswa Smp, Shoimatun Febriyani, Hadi Suwono, Ibrohim Ibrohim
Potensi Model Inkuiri Terbimbing Dipadu Edutainment Terhadap Penguasaan Konsep Siswa Smp, Shoimatun Febriyani, Hadi Suwono, Ibrohim Ibrohim
Jurnal Pendidikan: Teori, Penelitian, dan Pengembangan
This study aims to investigate the potencial of guided inquiry models edutainment combined toward the mastery concepts. The design of this research use quasi experiment. The population of this studdy was all the second grades students of SMP N 18 Malang while the sampling of the study was 8G, 8H dan 8E. The used instrument was 20 multiple choice to measure the mastery concepst of students. The result of the study was guided inquiry models edutainment combined potencially can improve mastery of concepts students.
Expressive Writing Untuk Keterampilan Mengelola Emosi Marah Siswa, Nurhayani Maudi, Triyono Triyono, Dany M. Handirini
Expressive Writing Untuk Keterampilan Mengelola Emosi Marah Siswa, Nurhayani Maudi, Triyono Triyono, Dany M. Handirini
Jurnal Pendidikan: Teori, Penelitian, dan Pengembangan
This study aims to develop a guide to training anger management skills using the expressive writing method for junior high school students. The method used in this study is a research and development model. The trial subjects in this study consisted of instructional media experts, guidance and counseling expertsand prospective users or school counselors. the instruments used are in the form of expert assessment instruments and prospective user assessment instruments. The results of the trial consisted of quantitative data and qualitative data. Data analysis techniques in this research and development are descriptive analysis techniques. The results of the assessment of …
Miskonsepsi Asam Basa Berbasis Multipel Representasi Pada Lintas Jenjang Pendidikan, Isnaini Yunitasari, Hayuni Retno Widarti, Nazriati Nazriati
Miskonsepsi Asam Basa Berbasis Multipel Representasi Pada Lintas Jenjang Pendidikan, Isnaini Yunitasari, Hayuni Retno Widarti, Nazriati Nazriati
Jurnal Pendidikan: Teori, Penelitian, dan Pengembangan
This study aims to describe acid-base misconceptions across levels of education using multiple representation based diagnostic tests. The research method is quantitative descriptive. Analysis process of misconceptions using modified CRI. The validity of diagnostic tests is between 0.197 to 0.798, and reliability is 0.753 and 0.626. The research subjects were 224 people consisting of class XI students, class XII students, second semester students, and 4th semester students. The results showed that the average percentage of acid-base misconceptions in class XI students to 4th semester students respectively was 50.30%; 56.84%; 53.81%; and 41.07%. Misconceptions that often occur in students and students …
Penerapan Model Fan-N-Pick Dan Inside-Outside Circle Untuk Meningkatkan Keterampilan Sosial Dan Hasil Belajar Siswa Kelas Iv Sekolah Dasar, Anita Nurgufriani, Budi Eko Soetjipto, Mohammad Zainuddin
Penerapan Model Fan-N-Pick Dan Inside-Outside Circle Untuk Meningkatkan Keterampilan Sosial Dan Hasil Belajar Siswa Kelas Iv Sekolah Dasar, Anita Nurgufriani, Budi Eko Soetjipto, Mohammad Zainuddin
Jurnal Pendidikan: Teori, Penelitian, dan Pengembangan
The purpose of the study is to describe the application of the model FNP and IOC to improve the social skills and the learning outcomes of student class IV SDN 3 Besuki. Type of this research was PTK that includes two cycles. Research was conducted at SDN 3 Besuki, the subjectof this research is the students of class IV SDN 3 Besuki amounted to 32 people. Data collection: observation, interview, test, questionnaire, and documentation. The techniques of data analysis: reduction, data presentation and conclusion. The result of this research shows that the increased in social skills and the students learning …
Menulis Teks Prosedur Dengan Strategi Raft, Malinda Fatmawati, Heri Suwignyo, Nita Widiati
Menulis Teks Prosedur Dengan Strategi Raft, Malinda Fatmawati, Heri Suwignyo, Nita Widiati
Jurnal Pendidikan: Teori, Penelitian, dan Pengembangan
This research and development has two objectives, namely to produce teaching materials and test the effectiveness of teaching materials. The development model used is 4-D. The stages of 4-D development consist of (1) define (determination), (2) design (design), (3) development (development), (4) disseminate (dissemination). The results of validation tests conducted by instructional materials experts, learning experts, and practitioners stated that the teaching materials for writing procedure texts using the RAFT strategy are feasible to implement. The effective test results state that the data obtained from field tests are normally distributed, namely> 0.05. The significance obtained is <0.05. This means that teaching materials are effectively used in learning.
Kontribusi Model Pembelajaran Web Centric Cource Dan Self-Efficacy Komputer Terhadap Prestasi Belajar Siswa Paket Keahlian Rekayasa Perangkat Lunak Di Smk, Mohammad Mahmudi, Djoko Kustono, Maftuchin Romlie
Kontribusi Model Pembelajaran Web Centric Cource Dan Self-Efficacy Komputer Terhadap Prestasi Belajar Siswa Paket Keahlian Rekayasa Perangkat Lunak Di Smk, Mohammad Mahmudi, Djoko Kustono, Maftuchin Romlie
Jurnal Pendidikan: Teori, Penelitian, dan Pengembangan
This study aims to determine (1) significant influence of students learning motivation with Basic Programming learning outcomes, (2) significant effect of students computer self-efficacy with Basic Programming learning outcomes, (3) Significant differences in Basic Programming learning outcomes between groups of students who are taught with a web centric course are equipped with modules with groups of students who are taught with conventional models with modules. This study employed Nonequievalent Control Group Design with the consideration that the choosing of experimental and control group could not be determined by individual random sampling but it was done through assignment random sampling to …
Keefektifan Dan Minat Baca Siswa Pada Penggunaan Buku Pengayaan Non Fiksi Di Sd, Fridolin Vrosansen Borolla, Lia Yuliati, I Made Suardana
Keefektifan Dan Minat Baca Siswa Pada Penggunaan Buku Pengayaan Non Fiksi Di Sd, Fridolin Vrosansen Borolla, Lia Yuliati, I Made Suardana
Jurnal Pendidikan: Teori, Penelitian, dan Pengembangan
This study aims to describe the results of the effectiveness and interest in reading the nonfiction enrichment book in elementary school. The research method used is research and development data analysis techniques namely quantitative and qualitative descriptive. The test results for the level of material, language, and design validation in the teacher's books were 88.23% and 87.7% of the students' books. Then the feasibility test results are 88,75% and the withdrawal test is 93%. The results of the effectiveness test before using the product are 59,23 %%, and then using the product that is 85%. Meanwhile students' reading interest depends …
Status Of Women In Academic Ophthalmology, Sonal S. Tuli
Status Of Women In Academic Ophthalmology, Sonal S. Tuli
Journal of Academic Ophthalmology
Status of Women in Academic Ophthalmology
Identification And Evaluation Of Antibacterial Compounds From The Vibrio Sp. Associated With The Ascidian Pycnoclavella Diminuta, Abdurraafi’ Maududi Dermawan, Elin Julianti, Masteria Yunovilsa Putra
Identification And Evaluation Of Antibacterial Compounds From The Vibrio Sp. Associated With The Ascidian Pycnoclavella Diminuta, Abdurraafi’ Maududi Dermawan, Elin Julianti, Masteria Yunovilsa Putra
Pharmaceutical Sciences and Research
This study aims to obtain secondary metabolites that have antibacterial activity from bacteria endophytic of ascidian Pycnoclavella diminuta collected from the coast of Bitung, North Sulawesi, Indonesia. The research was started with screening antibacterial activity of six bacteria isolated from P. diminuta. The active bacteria were selected for identification using standard biological molecular method and further fermentation to produce secondary metabolites. The isolation of secondary metabolites was conducted by various chromatography method and then selected fraction was based on the antibacterial activity from bioautography results. The result showed that the active isolate by coding M2.Tnk.Bt 5.10-3.2 was identified as Vibrio …
Cytotoxic Activity Of Stem Of Pycnarrhena Cauliflora Through Apoptosis Induction On Human Breast Cancer Cell Line T47d, Masriani, Rudiyansyah, Rini Muharini, Eny Enawaty
Cytotoxic Activity Of Stem Of Pycnarrhena Cauliflora Through Apoptosis Induction On Human Breast Cancer Cell Line T47d, Masriani, Rudiyansyah, Rini Muharini, Eny Enawaty
Pharmaceutical Sciences and Research
Cytotoxic activities of extracts of Pycnarrhena cauliflora leaves, stems and roots on some human cancer cells have been known. However, the cytotoxicity of stem of Pycnarrhena cauliflora on human breast cancer cell line T47D through an apoptosis induction has not been proven yet. This study was an effort in understanding the cytotoxic activity of stem of Pycnarrhena cauliflora through apoptosis induction. The crude ethanol extract was partitioned between n-hexane and dichloromethane at pH 3, 7 and 9, which was subsequently tested for their cytotoxic activity against human breast cancer cell line T47D by using 3-(4,5-dimethylthiazol-2-yl)- 2,5-diphenyltetrazolium bromide (MTT). Flow cytometric …