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A Mathematical Analysis Of A Model Of Drug Action On Intracellular Calcium Dynamics, Marah Townzen Funk

2019 Fall Honors Capstone Projects - Archive

The dysregulation of intracellular Ca2+ dynamics is a hallmark feature of several types of cancer. Administering a combination of a drug that blocks store-operated Ca2+ entry and a drug that inhibits tyrosine kinases is a novel chemotherapeutic approach currently being explored. Using data from experimental trials of these drugs, an existing model of Ca2+ dynamics was modified via the Michaelis-Menten theory of enzyme kinetics to reflect the behavior of the cell upon administration of the drugs. Mathematical analyses were performed to determine the overall repercussions of this modification. This included sensitivity analysis to reveal the model's sensitivity to changes to …

A Robust Controller Design For A Tailless Uav With Effective Control Allocation, Ethem Hakan Orhan

Mechanical and Aerospace Engineering Theses - Archive

Attempts to completely remove the tails from aircraft can be dated back to the early days of modern aviation. A number of stability and control problems arising from the unique characteristics of the configuration resulted in poor handling qualities and some dangerous flight characteristics in the early designs. Lately, this configuration is becoming widespread again and the current state-of-the-art of fly-by wire technology and modern control design techniques enable design of tailless aircraft which are safe to fly. In this thesis, a study on the application of modern robust control design techniques on a tailless UAV is presented. A nonlinear …

Oxygen Deficient Perovskites: Effect Of Structure On Electrical Conductivity, Magnetism And Electrocatalytic Activity., Ram Krishna Hona

Electronic Theses and Dissertations

The present thesis deals with the synthesis and study of the physico-chemical properties of perovskite based oxide materials. Several novel oxygen deficient perovskites (ODP) have been synthesized by conventional solid state synthesis method. The novel compounds are CaSrFe₂O_6-δ, CaSrFeCoO_6-δ, Ca₂Fe_1.5Ga_0.5O₅, CaSrFeGaO₅ and BaSrFe₂O₅. Their magnetic, charge transport and electrocatalytic properties have been studied. Structural effect on electrical conductivity, magnetic and electrocatalytic properties have been studied in some series of ODPs. CaSrFe₂O_6-δ, CaSrFeCoO_6-δ, Ca₂Fe …

Brokering Words And Work: Complexities Of Literacy Sponsorship In The Oilfields Of South Texas., Jennifer L. Marciniak

Electronic Theses and Dissertations

This research is an investigation of workforce recruitment language as the “leading edge” of literacy sponsorship as it pertains to blue-collar rig and service workers in the South Texas oilfields. Using Deborah Brandt’s Literacy in American Lives as a framework for this study, I conducted interviews with 10 rig and service workers and labor market intermediary administrators about the perceptions and expectations of literacy use in oilfield work. My inquiry begins by first learning about workers’ experiences with recruitment into the industry. Then, to understand more about how the industry communicates literacy expectations to these workers, I look at recruitment …

Perceptions Of Restorative Practices Among Black Girls: Talking Circles In An Urban Alternative Middle School., Vanessa Marie Mcphail

Electronic Theses and Dissertations

Research suggests that Restorative Justice approaches have shown promise in terms of their impact on school climate, student behavior, and relationships. The purpose of this study is to explore Black female students’ perceptions of Restorative Practice (RP) talking circles at an alternative school. The study examined literature on Zero Tolerance, School Discipline Disparities, African American Female students, Intersectionality, Restorative Justice, and Alternative Schools. A qualitative case study method was used for this study, drawing from two sources: (a) face-to-face interviews and (b) observations of the Black female students who attend the alternative school and participate in the talking circles. Analyses …

Effects Of A Writing Instructional Package For Students With Moderate Intellectual Disability., Beth Newberry Gurney

Electronic Theses and Dissertations

The development of writing skills is one of the most complex competencies that students are expected to master (Saddler, 2013). Limited research has been conducted on the acquisition of writing skills for students with moderate and severe intellectual disability. Even fewer studies have examined the acquisition of sentence construction skills. The current study examines the effects of a writing instructional package using peer tutoring, response prompting, and sentence frames to teach students with moderate intellectual disability to construct sentences related to adapted grade-level social studies content. Four seventh grade students without disabilities were trained to implement the writing instructional package …

Laser Spectroscopic Investigations Of Organic Alkoxy And Peroxy Radicals., Md Asmaul Reza

Electronic Theses and Dissertations

Understanding the mechanism of combustion reactions is key for advancing internal combustion engine design, improving the efficiency of ignition chemical reactions, and reducing pollutant formation. In order to model the extremely complicated chemical kinetics of combustion processes, it is critical to detect and identify transient reactive chemical intermediates, particularly free radicals. Hence, it needs to be fully understood the gas-phase chemistry of organic compounds in the lower atmosphere. Over the past fifty years, parallel advancement in observational, experimental, and theoretical techniques, tremendous strides have been made in our understanding of the role of organic compounds in the atmosphere. Combustion chemistry …

Quantifying The Effectiveness Of Cedar Revetment In Mitigating Bank Erosion In Riceford Creek, Minnesota, Talia A. Klein

Graduate Theses/Dissertations

Southeastern Minnesota has incised streams that are susceptible to bank erosion. Previously, efforts have been made to identify sections of Riceford Creek that have high erosion susceptibility using the Bank Erosion Hazard Index (BEHI). Locally harvested cedars were then used as a revetment strategy to mitigate erosion of the stream banks prioritized by the BEHI analysis. This study aims to 1) determine if cedar revetment effectively mitigates bank erosion in Riceford Creek and 2) determine if the BEHI method is an effective way of quantifying erosion hazard in Riceford Creek. This study focuses on two sections in Riceford Creek where …

Groups Satisfying The Converse To Lagrange's Theorem, Jonah N. Henry

Graduate Theses/Dissertations

Lagrange’s theorem, which is taught early on in group theory courses, states that the order of a subgroup must divide the order of the group which contains it. In this thesis, we consider the converse to this statement. A group satisfying the converse to Lagrange’s theorem is called a CLT group. We begin with results that help show that a group is CLT, and explore basic CLT groups with examples. We then give the conditions to guarantee either CLT is satisfied or a non-CLT group exists for more advanced cases. Additionally, we show that CLT groups are properly contained between …

Effects Of The Dihydrouracil Lesion On Dna Using 1h/31p 1d And 2d Solution Nmr, Benjamin M. Boyd

Graduate Theses/Dissertations

The effects of the dihydrouracil lesion in DNA were studied using two dimensional NMR spectroscopy. The sequence used was based off of the Drew-Dickerson Dodecamer, with the cytosine in the three position replaced by a dihydrouracil. All of the nonexchangeable proton chemical shifts, with the exception of the H2, H5’, and H5’’, of the lesioned DNA were identified using NOESY spectra and then compared to the chemical shift values of the Drew Dickerson Dodecamer. The largest differences in chemical shifts were observed in the nucleotides neighboring the lesion, both within the strand and on the opposite strand. The imino exchangeable …

Linking Experiential Workshops And Increased Stem Interest Among First- And Second- Generation Latino Youth, Jeff Sallee, Ronald Cox, Rita Flores, Steven Cooper

Journal of Youth Development

Extension outreach professionals are searching for new methods to target the growing population of Latino students. Oklahoma State University faculty in the Animal Science department and the 4-H Youth Development program partnered to sponsor a 4-H STEM Institute designed to promote science, technology, engineering, and math to Latino students in the Unidos Se Puede program. The STEM Institute was designed to introduce the Latino youth to college life and STEM based career opportunities. The program was evaluated utilizing the 4-H Common Measures Science instruments. The results indicate a positive impact on the youths’ perception of STEM as a career option. …

December 2019 News Releases, University Of Montana--Missoula. Office Of University Relations

University of Montana News Releases, 1928, 1956-present

No abstract provided.

The Promise And Peril Of Using Disability Law As A Tool For School Reform, Claire Raj

Faculty Publications

No abstract provided.

Benefits Of School Gardening On Low-Income Elementary School Students, Caitlynn Lange

Capstone Projects and Master's Theses

The increase in obesity rates in America’s youth could be a reflection of undernourished school lunches, a decrease in physical activity, and the lack of knowledge of health and nutrition. Children who come from a low-income family are more likely to be affected by these circumstances. School gardening may be a way of replacing those impacts. This senior capstone research project examines the benefits of school gardening on low-income elementary school students when implementing as part of the curriculum in schools.

Effective Exploration Behavior For Chemical-Sensing Robots, Kevin Nickels, Hoa Nguyen, Duncan M. Frasch, Timothy F. Davison

Engineering Faculty Research

Mobile robots that can effectively detect chemical effluents could be useful in a variety of situations, such as disaster relief or drug sniffing. Such a robot might mimic biological systems that exhibit chemotaxis, which is movement towards or away from a chemical stimulant in the environment. Some existing robotic exploration algorithms that mimic chemotaxis suffer from the problems of getting stuck in local maxima and becoming “lost”, or unable to find the chemical if there is no initial detection. We introduce the use of the RapidCell algorithm for mobile robots exploring regions with potentially detectable chemical concentrations. The RapidCell algorithm …

Porous Silicon Photonics At Unity Confinement Factors For Surface Adlayer Biosensing, Tahmid Hassan Talukdar

All Theses

Guided wave-optics is an emergent platform for label free optical biosensing. However, device sensitivity toward surface-attached biomolecules is directly restricted because of only evanescent interaction and low modal overlap with the active sensing region. In this work, we demonstrate a mesoporous silicon waveguide design created via a novel inverse processing technique that overcomes the limitations imposed by evanescent field sensing by achieving maximal transverse confinement factor in the active sensing region. Our sensor can also maintain this confinement factor and sensitivity across a large dimensional variation while preserving single-mode operation. Our devices are characterized in a Fabry-Perot interferometer configuration and …

The Impact Of Social And Cultural Factors On Minority Students’ Participation In An International Baccalaureate Diploma Program, Elizabeth Scott-Janda

Dissertations

Although concern about mathematical achievement inequities has become widespread, even in well-funded, high-performing high schools, unequal outcomes for minority and disadvantaged students can seem persistent and difficult to change despite strong efforts. This project reports on an ethnographic study that examined how social environments within schools can affect students’ choices of whether or not to attempt advanced coursework in mathematics, especially among marginalized groups like Hispanic minorities, low socio-economic status (SES) and rural populations. It considered how social and peer environments affect students’ approaches to schooling, and decisions they make that will have long-term implications for their futures. In particular, …

Foreword To Relativizing Newton, Vernon L. Smith

Economics Faculty Books and Book Chapters

A foreword to Ramzi Suleiman's book Relativizing Newton.

Multimodal Mobile Sensing Systems For Physiological And Psychological Assessment, Nguyen Phan Sinh Huynh

Dissertations and Theses Collection (Open Access)

Sensing systems for monitoring physiological and psychological states have been studied extensively in both academic and industry research for different applications across various domains. However, most of the studies have been done in the lab environment with controlled and complicated sensor setup, which is only suitable for serious healthcare applications in which the obtrusiveness and immobility can be compromised in a trade-off for accurate clinical screening or diagnosing. The recent substantial development of mobile devices with embedded miniaturized sensors are now allowing new opportunities to adapt and develop such sensing systems in the mobile context. The ability to sense physiological …

Nonlinear Functional Models On Causal Inference, Rong Jiao

Dissertations and Theses (Open Access)

Statistical analysis has experienced significant progress on association study, but it remains elusive to understand the etiology and mechanism of complex phenotypes. As a major analytical platform, association analysis may hamper the theoretic development of biomedical science and its application. Thus, many researchers suggest making the transition from association to causation. The mainstream of research in genetics and epigenetics data analysis focuses on statistical association or exploring statistical dependence between variables. Despite significant progress in dissecting the genetic architecture of complex diseases by genome-wide association studies (GWAS), the signals identified by association analysis can only explain a small proportion of …

2019 December - Tennessee Monthly Climate Report, Tennessee Climate Office, East Tennessee State University

Tennessee Climate Office Monthly Reports

No abstract provided.

Jnchc Front & Back Matter, Vol. 20, No 2, Fall/Winter 2019

Journal of the National Collegiate Honors Council Online Archive

Cover

Masthead

Contents

Call for Papers, Editorial Policy, & Submission Guidelines

Dedication -- Art L. Spisak

About the Authors

About the NCHC Monograph Series

Order form

Back cover

R Foundation News, Torsten Hothorn

The R Journal

Membership fees and donations received between 2019-09-05 and 2020-02-24.

Conference: Report Conectar 2019, Marcela Alfaro Córdoba, Frans Van Dunné, Agustín Gómez Meléndez, Jacob Van Etten

The R Journal

ConectaR 2019: Encuentro de Usuarios R en Latinoamérica, took place during January 24-26, 2019 at the University of Costa Rica, in San José, Costa Rica. It was the first event in Central America endorsed by The R Foundation, and it was held completely in Spanish. The majority of the attendants were from Costa Rica (85%), but we had participants from 12 countries: Costa Rica, Guatemala, Peru, Colombia, Mexico, Argentina, Uruguay, Chile, Spain, the Netherlands, France and the USA. The three-day event consisted of talks, workshops, and poster sessions.

Lpirfs: An R Package To Estimate Impulse Response Functions By Local Projections, Philipp Adämmer

The R Journal

Impulse response analysis is a cornerstone in applied (macro-)econometrics. Estimating impulse response functions using local projections (LPs) has become an appealing alternative to the traditional structural vector autoregressive (SVAR) approach. Despite its growing popularity and applications, however, no R package yet exists that makes this method available. In this paper, I introduce lpirfs, a fast and flexible R package that provides a broad framework to compute and visualize impulse response functions using LPs for a variety of data sets.

Resampling-Based Analysis Of Multivariate Data And Repeated Measures Designs With The R Package Manova.Rm, Sarah Friedrich, Frank Konietschke, Markus Pauly

The R Journal

Nonparametric statistical inference methods for a modern and robust analysis of longitudinal and multivariate data in factorial experiments are essential for research. While existing approaches that rely on specific distributional assumptions of the data (multivariate normality and/or equal covariance matrices) are implemented in statistical software packages, there is a need for user-friendly software that can be used for the analysis of data that do not fulfill the aforementioned assumptions and provide accurate p value and confidence interval estimates. Therefore, newly developed nonparametric statistical methods based on bootstrap- and permutation-approaches, which neither assume multivariate normality nor specific covariance matrices, have been …

The Landscape Of R Packages For Automated Exploratory Data Analysis, Mateusz Staniak, Przemysław Biecek

The R Journal

The increasing availability of large but noisy data sets with a large number of heterogeneous variables leads to the increasing interest in the automation of common tasks for data analysis. The most time-consuming part of this process is the Exploratory Data Analysis, crucial for better domain understanding, data cleaning, data validation, and feature engineering

There is a growing number of libraries that attempt to automate some of the typical Exploratory Data Analysis tasks to make the search for new insights easier and faster. In this paper, we present a systematic review of existing tools for Automated Exploratory Data Analysis (autoEDA). …

Roahd Package: Robust Analysis Of High Dimensional Data, Francesca Ieva, Anna Maria Paganoni, Juan Romo, Nicholas Tarabelloni

The R Journal

The focus of this paper is on the open-source R package roahd (RObust Analysis of High dimensional Data), see Tarabelloni et al. (2017). roahd has been developed to gather recently proposed statistical methods that deal with the robust inferential analysis of univariate and multivariate functional data. In particular, efficient methods for outlier detection and related graphical tools, methods to represent and simulate functional data, as well as inferential tools for testing differences and dependency among families of curves will be discussed, and the associated functions of the package will be described in details.

Jomo: A Flexible Package For Two-Level Joint Modelling Multiple Imputation, Matteo Quartagno, Simon Grund, James Carpenter

The R Journal

Multiple imputation is a tool for parameter estimation and inference with partially observed data, which is used increasingly widely in medical and social research. When the data to be imputed are correlated or have a multilevel structure — repeated observations on patients, school children nested in classes within schools within educational districts — the imputation model needs to include this structure. Here we introduce our joint modelling package for multiple imputation of multilevel data, jomo, which uses a multivariate normal model fitted by Markov Chain Monte Carlo (MCMC). Compared to previous packages for multilevel imputation, e.g. pan, jomo adds the …

Cvcrand: A Package For Covariate-Constrained Randomization And The Clustered Permutation Test For Cluster Randomized Trials, Hengshi Yu, Fan Li, John A. Gallis, Elizabeth L. Turner

The R Journal

The cluster randomized trial (CRT) is a randomized controlled trial in which randomization is conducted at the cluster level (e.g., school or hospital) and outcomes are measured for each individual within a cluster. Often, the number of clusters available to randomize is small (≤ 20), which increases the chance of baseline covariate imbalance between comparison arms. Such imbalance is particularly problematic when the covariates are predictive of the outcome because it can threaten the internal validity of the CRT. Pair-matching and stratification are two restricted randomization approaches that are frequently used to ensure balance at the design stage. An alternative, …