Digital Commons Network^™

Mathematical Modeling, Analysis, Simulation Of The Opioid Crisis With Prescription And Social Drug Addiction Models, Kirthi Kumar

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.

Managing A Conflict-Related, Open Fracture With Drug-Resistant Infections: The Case Of A Wounded Syrian Refugee In The Hashemite Kingdom Of Jordan, Alex Green

Clinical Research in Practice: The Journal of Team Hippocrates

A critical appraisal and clinical application of Uruc V, Ozden R, Duman IG, Dogramaci Y, Yengil E, Karapinar S, Karakus A, Kalaci A. Major musculoskeletal injuries and applied treatments in the current conflicts in Syria. Acta Medica Mediterranea. 2014;30(3):637-644.

Nocardia Beijingensis: A Rare And Unusual Cause Of Intracranial Abscess, Lakshpaul Chauhan Md, Nirali Vassa Md, Elizabeth Henderson Md, Ateeq Mubarik Md, Danish M. Siddiq Md, Abdulmagid Eddib Md

Infectious Disease

Background : Nocardia species are thin, aerobic, filamentous, gram-positive bacilli that are ubiquitous in soil worldwide. Nocardia infections are divided into three main categories: pulmonary nocardiosis, disseminated nocardiosis, and cutaneous nocardiosis.

Methods : We present a case of cerebral nocardiosis in an immunocompetent patient caused by Nocardia beijingensis (NB).

Results : A 60-year-old Caucasian lady from Florida with type 2 diabetes mellitus, hypertension, hyperlipidemia, presented to the emergency room with complaints of altered mentation. Per husband, she was having episodes of emesis and diarrhea three days prior to admission that resolved however, her mentation significantly deteriorated to where she was …

Uab Researchers Receive U54 Grant, Join Rare Diseases Consortium, Alicia Rohan

Browse All News

No abstract provided.

Antimicrobial Stewardship In Long-Term Care Facilities: Focus On Suspected Uti, Margery Shane

Biennial Convention (CONV)

There is a high prevalence of asymptomatic bacteriuria in elderly long-term care facility (LTCF) residents. Antibiotics are frequently prescribed in reflex to diagnostic tests in the absence of signs or symptoms of urinary tract infection (UTI). An evidence-based eLearning module was developed to improve antibiotic stewardship regarding UTI in LTCFs.

Data Analytics For Diagnosis And Prediction Of Central Line-Associated Bloodstream Infections In Critical Care Units, Mary A. Hooshmand, Ramin Moghaddass, Christine Toledo, Erotokritos Skordilis

Biennial Convention (CONV)

Central line-associated bloodstream infections (CLABSI) are among leading causes of in-hospital deaths in the US and are a significant factor for increased morbidity, mortality and health care costs. This study examined significant attributes for CLABSI positive cases within intensive care units to develop a CLABSI hazard rate and risk score.

Ecthyma Gangrenosum In An Immunocompromised Patient Without Detectable Bacteremia, Jonathan Miles, Alex Mari, Matthew Crabtree, Vinod Nambudiri, Jilian Sansbury

Dermatology

Ecthyma gangrenosum (EG) is typically pathognomonic of Pseudomonas aeruginosa bacteremia among immunocompromised patients, particularly with underlying malignancy. Recently, other pathogens and clinical histories have been implicated, challenging the classic picture of patients with EG. The cutaneous findings in patients follow a pattern of lesion progression from indurated pustules and hemorrhagic vesicles evolving to necrotic ulcers with central black eschar and surrounding erythema. While lesions typically occur on the perineum or lower extremities, their presence has also been described elsewhere. Herein, we describe a case of an immunocompromised man with chronic lymphocytic leukemia and multiple myeloma actively undergoing chemotherapy presenting with …

Changes In Body Mass Index And Atherosclerotic Disease Risk Score After Switching From Tenofovir Disoproxil Fumarate To Tenofovir Alafenamide., Jason J. Schafer, Kaitlin N. Sassa, Jaclyn R. O'Connor, Ayako Shimada, Scott W. Keith, Joseph A. Desimone

College of Pharmacy Faculty Papers

Background: Switching from tenofovir disoproxil fumarate (TDF) to tenofovir alafenamide (TAF)-containing antiretroviral therapy (ART) can improve renal function and bone mineral density in people with human immunodeficiency virus (PWH). The switch can also negatively influence cholesterol, but changes in body mass index (BMI) and atherosclerotic cardiovascular disease (ASCVD) risk are unknown.

Methods: This retrospective observational study evaluated BMI and ASCVD risk score changes in virologically suppressed PWH who switched from TDF to TAF without switching other ART regimen components. Adults on TDF for ≥1 year with 2 consecutive HIV ribonucleic acid values/mL before a TAF switch were included. Body weight, …

Improving Nurses' Identification Of Sepsis In The Hospitalized Elderly, Aldrin U. Nieves

Biennial Convention (CONV)

A direct practice improvement (DPI) project was implemented at the acute care for the elderly (ACE) unit of a large urban trauma hospital in Northern California to determine whether an evidence-based educational intervention for staff registered nurses (RNs) would improve the accuracy of sepsis screenings performed on elderly hospitalized patients.

Emergence Of Bacterial Meningitis In Ghana: Implications For Nursing Care, Gloria Achempim-Ansong, Linda Norman, Lydia Aziato, Gladys Dzansi

Biennial Convention (CONV)

Bacterial meningitis is a seasonal epidemic which represents a serious public health problem. Morbidity rates are high with peak mortality rates of 50%. Nurses' perspectives on the implications for its spread was explored to determine response strategies and implications for care.

Htlv-1 Viral Oncogene Hbz Drives Bone Destruction In Adult T Cell Leukemia, Jingyu Xiang, Daniel A Rauch, Devra D Huey, Amanda R Panfil, Xiaogang Cheng, Alison K Esser, Xinming Su, John C Harding, Yalin Xu, Gregory C Fox, Francesca Fontana, Takayuki Kobayashi, Junyi Su, Hemalatha Sundaramoorthi, Wing Hing Wong, Yizhen Jia, Thomas J Rosol, Deborah J Veis, Patrick L Green, Stefan Niewiesk, Lee Ratner, Katherine N Weilbaecher

Open Access Publications

Osteolytic bone lesions and hypercalcemia are common, serious complications in adult T cell leukemia/lymphoma (ATL), an aggressive T cell malignancy associated with human T cell leukemia virus type 1 (HTLV-1) infection. The HTLV-1 viral oncogene HBZ has been implicated in ATL tumorigenesis and bone loss. In this study, we evaluated the role of HBZ on ATL-associated bone destruction using HTLV-1 infection and disease progression mouse models. Humanized mice infected with HTLV-1 developed lymphoproliferative disease and continuous, progressive osteolytic bone lesions. HTLV-1 lacking HBZ displayed only modest delays to lymphoproliferative disease but significantly decreased disease-associated bone loss compared with HTLV-1-infected mice. …

Ship Breaking And Its Future In Bangladesh, Jewel Das, Muhammed Ali Shahin

Journal of Ocean and Coastal Economics

Ship breaking is comparatively a sustainable business, particularly in the developing world, but the conditions where it is practiced is non-sustainable. Ship breaking is the process of dismantling ships and selling their parts - primarily the steel - for scrap. The main impetus for breaking a ship down is that maintenance costs go up as a ship ages. Shipping companies also have to pay port charges, crew salaries and oil fees for their ships, so when they are no longer economically viable they are sold to ship recyclers who strip the old ships down, salvaging anything of value. Bangladesh is …

Blue Biotechnology, Renewable Energy, Unconventional Resources And Products As Emerging Frontiers At Sea, Sheikh Aftab Uddin, Mohammad Mahmudul Islam

Journal of Ocean and Coastal Economics

Blue biotechnology, renewable energy and unconventional marine living resources are considered as emerging frontiers for enhancing ocean-based blue economy in Bangladesh. Blue biotechnology can help both fisheries and aquaculture industry by producing fish varieties that can become quicker, more beneficial, and greater with tastier flesh, by developing gene transfer technology to be used to develop the growth of fish or by using of monoclonal antibodies and DNA probes to new diagnostic strategies for pathogens. Transformation of marine bioresources (main, co-product and by-products) into food, medicine, animal feed and related bio-based items i.e. cosmetics, nutritional supplements, enzymes, agrichemicals etc could help …

Review Of "Renatus’ Kayak: A Labrador Inuk, An American G.I. And A Secret World War Ii Weather Station" By Rozanne Enerson Junker, Isabel Campbell

Canadian Military History

Review of "Renatus’ Kayak: A Labrador Inuk, an American G.I. and a Secret World War II Weather Station" by Rozanne Enerson Junker.

“Money Helps”: People Who Inject Drugs And Their Perceptions Of Financial Compensation And Its Ethical Implications, Roberto Abadie, Brandon Brown, Celia B. Fisher

Department of Sociology: Faculty Publications

This study documents how people who inject drugs (PWID) in rural Puerto Rico perceive payments for participating in HIV epidemiological studies. In-depth interviews were conducted among a subset (n = 40) of active PWID older than 18 years of age who had been previously enrolled in a much larger study (N = 360). Findings suggest that financial compensation was the main motivation for initially enrolling in the parent study. Then, as trust in the researchers developed, participants came to perceive compensation as part of a reciprocal exchange in which they assisted researchers by providing a trustful account of their experiences …

Search, The Jackson Laboratory

Search Magazine

No abstract provided.

The Effect Of The 1918 Influenza Pandemic On U.S. Life Insurance Holdings, Dr. Joanna Short

Economics: Faculty Scholarship & Creative Works

This paper examines the effect of a sharp rise in mortality, the 1918 influenza epidemic, on life insurance holdings in the U.S. The BLS Cost of Living Surveys of 1918-1919 provide a unique opportunity to examine the effect of the pandemic—some households were surveyed before, and others during or shortly after the worst of the influenza outbreak. In addition, I use state-level insurance sales data to compare the increase in spending on insurance in states particularly hard hit by the epidemic, relative to those that were not. I find some evidence that, in the immediate aftermath of the epidemic, those …

Law & Health Care Newsletter, Fall 2019

Law & Health Care Newsletter

No abstract provided.

Marshall Magazine Autumn 2019, Marshall University

Marshall Magazine

No abstract provided.

Letter From The Editor-In-Chief: Journal Of Refugee & Global Health Volume 2, Issue 2, Ruth Carrico

Journal of Refugee & Global Health

No abstract provided.

Fall 2019, Seattle University

Seattle University Magazine

No abstract provided.

Interactions 2019, Thomas J. Long School Of Pharmacy And Health Sciences

Interactions

In each issue of Interactions, the School’s annual magazine you will find stories about students, faculty and alumni from each of our disciplines. Learn about the ways our students, faculty and alumni are impacting their communities through health care outreach. Read about their research and how they are contributing to advances in patient care. Meet our Alumni of the Year and get to know our faculty.

Validation Of A Host Response Test To Distinguish Bacterial And Viral Respiratory Infection., Emily C. Lydon, Ricardo Henao, Thomas W. Burke, Mert Aydin, Bradly P. Nicholson, Seth W. Glickman, Vance G. Fowler, Eugenia B. Quackenbush, Charles Cairns, Stephen F. Kingsmore, Anja K. Jaehne, Emanuel P. Rivers, Raymond J. Langley, Elizabeth Petzold, Emily R. Ko, Micah T. Mcclain, Geoffrey S. Ginsburg, Christopher W. Woods, Ephraim L. Tsalik

Emergency Medicine Articles

BACKGROUND: Distinguishing bacterial and viral respiratory infections is challenging. Novel diagnostics based on differential host gene expression patterns are promising but have not been translated to a clinical platform nor extensively tested. Here, we validate a microarray-derived host response signature and explore performance in microbiology-negative and coinfection cases.

METHODS: Subjects with acute respiratory illness were enrolled in participating emergency departments. Reference standard was an adjudicated diagnosis of bacterial infection, viral infection, both, or neither. An 87-transcript signature for distinguishing bacterial, viral, and noninfectious illness was measured from peripheral blood using RT-PCR. Performance characteristics were evaluated in subjects with confirmed bacterial, …

The Changing Role Of Rodenticides And Their Alternatives In The Management Of Commensal Rodents, Gary Witmer

United States Department of Agriculture Wildlife Services: Staff Publications

Rodents cause substantial damage and losses of foodstuffs around the world. They also transmit many diseases to humans and livestock. While various methods are used to reduce damage caused by rodents, rodenticides remain an important tool in the toolbox. However, like all tools, rodenticides have advantages and disadvantages. Several considerations are shaping the future of rodenticide use, including manufacturing and registration costs, concern about toxicity levels and nontarget animal hazards, potential hazards to children, reduced effectiveness of some formulations, and humaneness to the targeted rodents. Many of these disadvantages apply to anticoagulant rodenticides, and their use is being more restricted …

Meeting Overview: Interferon Lambda - Disease Impact And Therapeutic Potential, Thomas R. O'Brien, Howard A. Young, Raymond P. Donnelly, Ludmila Prokunina-Olsson

United States Public Health Resources

A meeting entitled, "Interferon Lambda: Disease Impact and Translational Potential," was held on the campus of the National Institutes of Health in Bethesda, Maryland, on October 25-26, 2018. To our knowledge, this was the first meeting that focused exclusively on interferon lambda (IFN-λ). The meeting's purpose was to enhance interdisciplinary communication and promote new collaborations. The gathering brought together an international group of scientists from a wide range of disciplines. Sessions included: IFN-λ Biology, Therapy and Genetic Variation; IFN-λ and Hepatitis C Virus Infection; IFN-λ in Other Infections; and IFN-λ - Hepatic Fibrosis and Cancer. The next meeting on IFN-λ …

Molecular Characterization Of Multidrug-Resistance In Gram-Negative Bacteria From The Peshawar Teaching Hospital, Pakistan, A. Masseron, L. Poirel, B. Jamil Ali, M. A. Syed, P. Nordmann

Section of Pulmonary & Critical Care

Extended-spectrum β-lactamases, carbapenemases, 16S rRNA methylases conferring pan-drug aminoglycoside resistance and colistin resistance were investigated among Gram-negative bacteria recovered from clinical samples (infections) from 200 individuals hospitalized at the Khyber Teaching Hospital of Peshawar, north Pakistan, from December 2017 to March 2018. Out of 65 isolates recovered, 19% were carbapenem resistant and 16% carried a bla NDM-1 gene, confirming the widespread distribution of NDM producers in this country. The association of the NDM carbapenem-resistance determinant, together with the extended-spectrum β-lactamase CTX-M-15 and 16S rRNA methylases, was frequent, explaining the multidrug-resistance pattern observed. All isolates remained susceptible to colistin.

The Kentucky Cabinet For Health And Family Services’ Response To The Hepatitis A Virus Outbreak In Kentucky: An Idea Model Analysis, Rachel Leigh Cato

Masters Theses & Specialist Projects

The hepatitis A crisis in Kentucky is unprecedented compared to other states. With thousands of hospitalizations and over 60 deaths in the state of Kentucky alone, there is a need to evaluate the government’s response to the hepatitis A virus (HAV) epidemic. Therefore, the instructional risk communication messages that are being conveyed by the Kentucky Cabinet for Health and Family Services (KCHFS) are instrumental in the education and action plans of Kentuckians who are at risk of contracting HAV.

This study utilizes the IDEA Model Thematic Analysis Codebook as a guide to analyze the KCHFS’ risk communication regarding the hepatitis …

Positive Genetic Associations Among Fitness Traits Support Evolvability Of A Reef-Building Coral Under Multiple Stressors, Rachel M. Wright, Hanaka Mera, Carly D. Kenkel, Maria Nayfa, Line K. Bay, Mikhail V. Matz

Biological Sciences: Faculty Publications

Climate change threatens organisms in a variety of interactive ways that requires simultaneous adaptation of multiple traits. Predicting evolutionary responses requires an understanding of the potential for interactions among stressors and the genetic variance and covariance among fitness-related traits that may reinforce or constrain an adaptive response. Here we investigate the capacity of Acropora millepora, a reef-building coral, to adapt to multiple environmental stressors: rising sea surface temperature, ocean acidification, and increased prevalence of infectious diseases. We measured growth rates (weight gain), coral color (a proxy for Symbiodiniaceae density), and survival, in addition to nine physiological indicators of coral and …

Mining’S Impact On Environmental And Human Health: A Case Study Of Ramba County’S Gold Mine, Vivika Fernes

Independent Study Project (ISP) Collection

This research project aims to gain a greater understanding of the health implications that Ramba County’s goldmine has on miners, their families, and the environment. While this study observes the community-at-large, inclusive of visiting miners and extended family members of workers, it will focus on women who engage in artisanal and small-scale gold mining (ASGM). Millions of people in the developing word depend on ASGM for their livelihood, evident in this case study in Ramba County. However, while gold is associated with wealth, there is great irony in the fact that those working within the mining industry are being exploited …

Private Prisons, Private Governance: Essay On Developments In Private-Sector Resistance To Privatized Immigration Detention, Danielle C. Jefferis

Northwestern Journal of Law & Social Policy

No abstract provided.