Digital Commons Network^™

Electrical Cardiometry And Near-Infrared Spectroscopy During Transfusion: A Prospective Observational Study, Barbara Smith Weaver

Biennial Convention (CONV)

This presentation reviews a single center prospective observational study investigating cardiovascular hemodynamics and perfusion in anemic and non-anemic premature infants during the transfusion. Topics include the use of electrical cardiometry and near infra-red spectroscopy, and statistically significant changes seen before and after transfusion unseen by current bedside neonatal monitoring.

Svtools: Population-Scale Analysis Of Structural Variation, David E Larson, Haley J Abel, Colby Chiang, Abhijit Badve, Indraniel Das, James M Eldred, Ryan M Layer, Ira M Hall

Open Access Publications

SUMMARY: Large-scale human genetics studies are now employing whole genome sequencing with the goal of conducting comprehensive trait mapping analyses of all forms of genome variation. However, methods for structural variation (SV) analysis have lagged far behind those for smaller scale variants, and there is an urgent need to develop more efficient tools that scale to the size of human populations. Here, we present a fast and highly scalable software toolkit (svtools) and cloud-based pipeline for assembling high quality SV maps-including deletions, duplications, mobile element insertions, inversions and other rearrangements-in many thousands of human genomes. We show that this pipeline …

Cabozantinib Versus Sunitinib For Untreated Patients With Advanced Renal Cell Carcinoma Of Intermediate Or Poor Risk: Subgroup Analysis Of The Alliance A031203 Cabosun Trial, Daniel J George, Colin Hessel, Susan Halabi, M Dror Michaelson, Olwen Hahn, Meghara Walsh, Joel Picus, Eric J Small, Shaker Dakhil, Darren R Feldman, Milan Mangeshkar, Christian Scheffold, Michael J Morris, Toni K Choueiri

Open Access Publications

Cabozantinib treatment prolonged progression-free survival (PFS) and improved objective response rate (ORR) compared with sunitinib in patients with advanced renal cell carcinoma (RCC) of intermediate or poor risk by International Metastatic Renal Cell Carcinoma Database Consortium (IMDC) criteria in the phase II CABOSUN trial (NCT01835158). In the trial, 157 patients were randomized 1:1 to receive cabozantinib or sunitinib, stratified by IMDC risk group and presence of bone metastases. Here, PFS and ORR, both determined by independent radiology committee (IRC), were analyzed by subgroups of baseline characteristics. Cabozantinib treatment was generally associated with improved PFS and ORR versus sunitinib across subgroups, …

School Readiness Profiles And Growth In Academic Achievement, Qianqian Pan, Kim T. Trang, Hailey R. Love, Jonathan Templin

Educational & Clinical Studies Faculty Research

The purpose of this research was to identify the presence of different school readiness profiles and to determine whether profiles could differentially predict academic growth. The Early Childhood Longitudinal Study: 2010-11 (ECLS-K: 2011) public data set was used, and participants were 14,954 first-time kindergarteners. The age of entering kindergarten ranged from 44.81 to 87.98 months with a mean of 76.13 months. In Study 1, a six-dimensional construct of school readiness was used: health, self-regulation, social and emotional development, language development, cognitive development, and approaches to learning. Results revealed 41 profiles with the top six school readiness profiles covering 85% of …

Seeing A Better World From Space, Carly Sakumura

Purdue GIS Day

Understanding change is essential to addressing our most pressing global challenges. Organizations need actionable insight to make critical decisions that affect communities, economies, and national security. As a global leader of advanced geospatial and space-based technology solutions, Maxar has an unprecedented ability to observe, analyze, and monitor these global changes. In this talk, I’ll discuss the cutting-edge research, technological capabilities, and imagery products and analytics we develop at Maxar to unlock the power of geospatial data to understand and navigate our changing world.

Student Information Use And Decision-Making In Innovation Competitions And The Impact Of Librarian Interventions, Heather A. Howard, Dave Zwicky

Libraries Faculty and Staff Scholarship and Research

At a large Midwestern university, librarians work closely with an annual undergraduate agricultural innovation competition to guide students through the process of conducting market research and assessing patentability. In 2018, the authors conducted an exploratory study using focus groups of students who had participated in that year’s competition in order to learn how students find and use information in a competition setting, to evaluate the impact of library support on the students’ success, and inform further assessment activities. Results showed that students used information from the library and from their own research, notably seeking out first-hand expertise, to practice evidence-based …

A Mixed-Methods Study Of Applying Andragogical Practices To An Online Tesol Teacher Training Course At A Midwestern University, Daisy Anne Mary Skelly

Dissertations

Preservice teachers needed to be prepared to teach culturally and linguistically diverse learners, because English learners continued to enroll in new geographic areas. In response to the reauthorization of the federal Elementary and Secondary Education Act, requirements for teaching culturally and linguistically diverse students were added to teacher certification programs at the state level. Universities offering teacher certification programs addressed new program requirements in different ways, including adding competencies to existing courses or creating new courses. The purpose of this mixedmethods study was to investigate the knowledge, pedagogical skill, and self-efficacy levels of preservice teachers and their perceptions of English …

Eva And Otto: Resistance, Refugees, And Love In The Time Of Hitler, Tom Pfister, Kathy Pfister, Peter Pfister

Purdue University Press Book Previews

Eva and Otto is a true story about German opposition and resistance to Hitler as revealed through the early lives of Eva Lewinski Pfister (1910–1991) and Otto Pfister (1900–1985). It is an intimate and epic account of two Germans—Eva born Jewish, Otto born Catholic—who worked with a little-known German political group that resisted and fought against Hitler in Germany before 1933 and then in exile in Paris before the German invasion of France in May 1940. After their improbable escapes from separate internment and imprisonment in Europe, Eva obtained refuge in America in October 1940 where she worked to rescue …

Political Activist + Public Servant?, Sharon Murchie

Language Arts Journal of Michigan

How do we write as political activists while also working as public servants? Do we have freedom of speech as public school teachers? Can—and should—our writing and our speech be censored? How can we write and work for social and political change, when we are charged with remaining apolitical in the classroom? This article outlines the limitations on teachers’ First Amendment Rights and is both a call to action and a call to caution.

Bobby Valentine Health & Recreation Center Newsletter, Valentine Health & Recreation Center

News, Magazines and Reports

No abstract provided.

Knowledge Sharing Behaviours And Patterns Among Academic Students: A Case Study Of Electrical Engineering Technology Students Of National Institute Of Construction Technology (Nict), Uromi, Edo State, Chidi Onuoha Kalu, Blessing Anegbemente Usiedo, Esther I. Chidi-Ka;U

Library Philosophy and Practice (e-journal)

Knowledge sharing among students is perceived as one of the most convenient and effective way to obtain knowledge. Knowledge sharing among academics students enhances the ability to seek studies-related help from one another and facilitates achieving outcomes of collective learning. Therefore, this paper investigates the knowledge sharing behaviours and patterns of Electrical/Electronic Engineering Technology Students of National Institute of Construction Technology, Uromi. The descriptive survey method was used. Questionnaire responses from 27 students were analysed to address questions related to how knowledge is shared between students and what motivates students to share knowledge. The study highlighted the barriers in knowledge …

An Experimental Investigation Of Victim Blaming In Sexual Assault: The Roles Of Victim Sexual Orientation, Coercion Type, And Stereotypes About Bisexual Women, Christina Dyar, Brian A. Feinstein, Raeann E. Anderson

Psychology Faculty Publications

Bisexual women are more likely to be sexually assaulted and to receive negative reactions to disclosures of sexual assault than heterosexual and lesbian women. However, few studies have examined the extent to which victim sexual orientation and related factors influence perceptions of sexual assault victims and perpetrators. To fill this gap, the current study used an experimental manipulation to examine the influence of victim sexual orientation and coercion type on perceptions of sexual assault victims and perpetrators. Participants (N = 826) were randomly assigned to read one of nine vignettes in which the sexual orientation of the female victim …

#Metoo: Why Now? What Next?, Deborah L. Rhode

Duke Law Journal

This Essay explores the evolution, implications, and potential of #MeToo. It begins by reviewing the inadequacies of sexual harassment law and policies that have permitted continuing abuse and that prompted the outrage that erupted in 2017. Discussion then turns to the origins of the #MeToo movement and assesses the changes that it has propelled. Analysis centers on which changes are likely to last and the concerns of fairness and inclusion that they raise. A final section considers strategies for sustaining the positive momentum of the movement and directing its efforts toward fundamental reform.

Traceable Dynamic Public Auditing With Identity Privacy Preserving For Cloud Storage, Yinghui Zhang, Tiantian Zhang, Rui Guo, Shengmin Xu, Dong Zheng

Research Collection School Of Computing and Information Systems

In cloud computing era, an increasing number of resource-constrained users outsource their data to cloud servers. Due to the untrustworthiness of cloud servers, it is important to ensure the integrity of outsourced data. However, most of existing solutions still have challenging issues needing to be addressed, such as the identity privacy protection of users, the traceability of users, the supporting of dynamic user operations, and the publicity of auditing. In order to tackle these issues simultaneously, in this paper, we propose a traceable dynamic public auditing scheme with identity privacy preserving for cloud storage. In the proposed scheme, a single …

The Impact Of The Content Of Online Customer Reviews On Customer Satisfaction: Evidence From Yelp Reviews, Langtao Chen

Business and Information Technology Faculty Research & Creative Works

As customers are increasingly participating in online product and service reviews, companies can leverage the content of those consumer reviews to improve or retain customer satisfaction. By using a panel data set collected from Yelp, this study empirically tests the effects of voting and sentiment of customer reviews on future customer satisfaction. The results show that cool votes on customer reviews have a positive impact on customer satisfaction in the next month. While average positive sentiment score has a positive effect on customer satisfaction of a restaurant, average negative score has a negative influence. In addition, the diversity of the …

Vitamon: Measuring Heart Rate Variability Using Smartphone Front Camera, Sinh Huynh, Rajesh Krishna Balan, Jeonggil Ko, Youngki Lee

Research Collection School Of Computing and Information Systems

We present VitaMon, a mobile sensing system that can measure the inter-heartbeat interval (IBI) from the facial video captured by a commodity smartphone's front camera. The continuous IBI measurement is used to compute heart rate variability (HRV), one of the most important markers of the autonomic nervous system (ANS) regulation. The underlying idea of VitaMon is that video recording of human face contains multiple cardiovascular pulse signals with different phase shift. Our measurement on 10 participants shows the significant time delay (36.79 ms) between the pulse signals measured at the jaw region and forehead region. VitaMon leverages deep neural network …

A Review Of Materials For Managing Bone Loss In Revision Total Knee Arthroplasty, Romina Shafaghi, Omar Rodriguez, Emil H. Schemitsch, Paul Zalzal, Stephen D. Waldman, Marcello Papini, Mark R. Towler

Chemical and Biochemical Engineering Faculty Research & Creative Works

In 2014–2015, 61,421 total knee arthroplasties (TKAs) were performed in Canada; an increase of about 20% over 2000–2001. Revision total knee arthroplasties (rTKAs) accounted for 6.8% of TKAs performed between 2014 and 2015, and this is estimated to grow another 12% by 2025. rTKAs are typically more complicated than primary TKAs due to the significant loss of femoral and tibial bone stock. The escalating demand and limitations associated with total knee arthroplasty and their revision drives the development of novel treatments. A variety of materials have been utilized to facilitate regeneration of healthy bone around the site of a knee …

The Role Of An Obstetric Navigator In Supporting The Pregnant Adolescent, Jaime Kupillas Msn, Rnc-Ob, Carolyn L. Davidson Phd, Rn, Ccrn-A, Arnp, Cphq, Nea-Bc, Cathyjo Catalano Msn, Rnc-Ob, C-Efm

Patient Care Services / Nursing

No abstract provided.

Surgical Considerations And Speech Outcomes In Infants Who Undergo Cochlear Implantation: Experience Of The King Abdullah Ear Specialist Center, Eman A. Hajr, Tahani Alotaibi, Nasser W. Alobida, Abdulrahman A. Alsanosi

Saudi Medical Journal

Objectives: To evaluate the feasibility and outcomes of cochlear implantation (CI) in infancy. Methods: All infants who underwent CI from January 2011 to October 2018 at a tertiary referral center in the Kingdom of Saudi Arabia were retrospectively reviewed. Demographic data, factors associated with early detection, and any surgical difficulties or postoperative complications were extracted from the medical records. The outcome of CI was determined by a speech pathologist. Results: Fifteen patients underwent CI during the study period (9 bilateral and performed simultaneously, 6 unilateral). The round window was difficult to identify in 5 cases. Incomplete electrode insertion because of …

The Integrity Of Marriage, Kaiponanea T. Matsumura

William & Mary Law Review

While the Supreme Court’s decision in Obergefell v. Hodges resolved a dispute about access to legal marriage, it also exposed a rift between the Justices about what rights, obligations, and social meanings marriage should entail. The majority opinion described marriage as a “unified whole” comprised of “essential attributes,” both legal and extralegal. The dissents, in contrast, were more skeptical about marriage’s inherent legal content. Justice Scalia, for instance, characterized marriage as a mere bundle of “civil consequences” attached to “whatever sexual attachments and living arrangements [the law] wishes.” This side debate has taken center stage in several recent disputes. In …

Combat And Trajectories Of Physical Health Functioning In Us Service Members, Ben Porter, George A. Bonanno, Paul D. Bliese, Christopher J. Philips, Susan P. Proctor

Faculty Publications

Introduction

Previous research has demonstrated that different forms of mental health trajectories can be observed in service members, and that these trajectories are related to combat. However, limited research has examined this phenomenon in relation to physical health. This study aims to determine how combat exposure relates to trajectories of physical health functioning in U.S. service members.

Methods

This study included 11,950 Millennium Cohort Study participants who had an index deployment between 2001 and 2005. Self-reported physical health functioning was obtained 5 times between 2001 and 2016 (analyzed in 2017), and latent growth mixture modeling was used to identify longitudinal …

The Importance Of Involvement On The Local Level, Audrey M. Calkins

University of Memphis Law Review

No abstract provided.

2019 (Fall) Ensi Informer Magazine, Morehead State University. Engineering Sciences Department

ENSI Informer Magazine Archive

The ENSI Informer Magazine published in the fall of 2019.

Frontiers In Precision Medicine Iv: Artificial Intelligence, Assembling Large Cohorts, And The Population Data Revolution, Adam Bress, Rich Albrechtsen, Monika Baker, Jorge L. Contreras, Zachary Fica, Austin Gamblin, Chelsea Ratcliff, Bianca E. Rich, Matt A. Szaniawski, Alyssa Thorman, Chad Vansant-Webb, Willard Dere

Utah Law Faculty Scholarship

Large cohort studies and more recently electronic medical records (EMR) are being used to collect massive amounts of genetic information. Implementation of artificial intelligence has become increasingly necessary to interpret this data with the goal of augmenting patient care. While it is impossible to predict what the future holds, policy makers are challenged to create guiding principles and responsibly roll out these new technologies. On March 22, 2019, the University of Utah hosted its fourth annual Precision Medicine Symposium focusing on artificial intelligence, assembling large cohorts, and the population data revolution. The symposium brought together experts in medicine, science, law …

Incorporating B Cell Activating Factor (Baff) Into The Membrane Of Rabies Virus (Rabv) Particles Improves The Speed And Magnitude Of Vaccine-Induced Antibody Responses., Joseph R Plummer, James P Mcgettigan

Department of Microbiology and Immunology Faculty Papers

B cell activating factor (BAFF) is a member of the tumor necrosis factor (TNF) superfamily of cytokines that links innate with adaptive immunity. BAFF signals through receptors on B cells, making it an attractive molecule to potentiate vaccine-induced B cell responses. We hypothesized that a rabies virus (RABV)-based vaccine displaying both antigen and BAFF on the surface of the same virus particle would target antigen-specific B cells for activation and improve RABV-specific antibody responses. To test this hypothesis, we constructed a recombinant RABV-based vector expressing virus membrane-anchored murine BAFF (RABV-ED51-mBAFF). BAFF was incorporated into the RABV particle and determined to …

A New 30 Meter Resolution Global Shoreline Vector And Associated Global Islands Database For The Development Of Standardized Ecological Coastal Units, Roger Sayre, Suzanne Noble, Sharon Hamann, Rebecca Smith, Dawn Wright, Sean Breyer, Kevin Butler, Keith Van Graafeiland, Charlie Frye, Deniz Karagulle, Dabney Hopkins, Drew Stephens, Kevin Kelly, Zeenatul Basher, Devon Burton, Jill Cress, Karina Atkins, D. Paco Van Sistine, Beverly Friesen, Revecca Allee, Tom Allen, Peter Aniello, Irawan Asaad, Mark John Costello, Kathy Goodin, Peter Harris, Maria Kavanaugh, Helen Lillis, Elonora Manca, Frank Muller-Karger, Bjorn Nyberg, Rost Parsons, Jusrin Saarinen, Jack Steiner, Adam Reed

Political Science & Geography Faculty Publications

A new 30-m spatial resolution global shoreline vector (GSV) was developed from annual composites of 2014 Landsat satellite imagery. The semi-automated classification of the imagery was accomplished by manual selection of training points representing water and non-water classes along the entire global coastline. Polygon topology was applied to the GSV, resulting in a new characterisation of the number and size of global islands. Three size classes of islands were mapped: continental mainlands (5), islands greater than 1 km² (21,818), and islands smaller than 1 km² (318,868). The GSV represents the shore zone land and water interface boundary, and …

Severing The Connection Between Sex Trafficking And U.S. Military Bases Overseas, Anna Belle Hoots

Articles & Chapters

The sex trafficking of women and girls by US. military men remains an issue plaguing US. military bases overseas. While the US. government has offered several solutions to combat this specific niche of sex trafficking, the legislation and policy put forth are insufficient to eradicate the problem. After assessing the intersection of sex trafficking and overseas US. military bases, this Note both discusses why and proposes how, through the use of Status of Forces Agreements (SOFAs), all US. military bases abroad can and must commit to the prevention of this egregious human rights violation. Because SOFAs grant wide latitude to …

A Pilot Study To Examine The Impact Of Beta-Alanine Supplementation On Anaerobic Exercise Performance In Collegiate Rugby Athletes, Charles R. Smith, Patrick S. Harty, Richard A. Stecker, Chad M. Kerksick

Faculty Scholarship

Beta-alanine (BA) is a precursor to carnosine which functions as a buffer assisting in the maintenance of intracellular pH during high-intensity efforts. Rugby is a sport characterized by multiple intermittent periods of maximal or near maximal efforts with short periods of rest/active recovery. The purpose of this pilot study was to evaluate the impact of six weeks of beta-alanine supplementation on anaerobic performance measures in collegiate rugby players. Twenty-one male, collegiate rugby players were recruited, while fifteen completed post-testing (Mean ± SD; Age: 21.0 ± 1.8 years, Height: 179 ± 6.3 cm, Body Mass: 91.8 ± 13.3 kg, % Body …

November 2019 News Releases, University Of Montana--Missoula. Office Of University Relations

University of Montana News Releases, 1928, 1956-present

No abstract provided.

Targeting Dna Repair In Metastatic Castration-Resistant Prostate Cancer (Mcrpc): Genomic Screening For A Clinical Trial Of Rucaparib, Alan Bryce, Mitchell E. Gross, Charles Redfern, Nicholas Vogelzang, Matthew Rettig, Thomas Stanton, Julie N. Graff, Sandhya Srinivas, Andrea Loehr, Wassim Abida

Articles, Abstracts, and Reports

Objectives: The high prevalence of men with mCRPC carrying pathogenic mutations in DNA damage repair (DDR) genes may have implications for clinical treatment, as poly(ADP-ribose) polymerase (PARP) inhibitors, such as rucaparib, have shown preliminary evidence of activity in these patients. The ongoing phase 2 TRITON2 study (NCT02952534) is evaluating rucaparib in mCRPC patients harboring a deleterious germline or somatic mutation in BRCA1, BRCA2, ATM, or other DDR gene. Here we present results from genomic screening of tissue and plasma samples from mCRPC patients.

Methods: Comprehensive genomic profiling was performed by Foundation Medicine, Inc., using FFPE tumor tissue …