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2019

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Factors Influencing ‘Stage Of Change’ Among Alcohol Use Disorder Patients In Rehabilitation Centers In Kathmandu, Nepal, Pranab Dahal Jan 2019

Factors Influencing ‘Stage Of Change’ Among Alcohol Use Disorder Patients In Rehabilitation Centers In Kathmandu, Nepal, Pranab Dahal

Chulalongkorn University Theses and Dissertations (Chula ETD)

INTRODUCTION: The ‘stages of change’ model defines behavior change as a process with a series of stages. Alcohol use disorder which includes ‘harmful use’ and ‘alcohol dependence’ is a serious public health concern. With the ever increasing prevalence of ‘alcohol use disorder’ there is an increasing need to better understand the complexities of behavior change among this group. METHODS: A cross- sectional survey was conducted in 8 alcohol and drug rehabilitation centers (residential treatment centers) of Kathmandu, Nepal, in September 2018, involving 225 male patients. AUDIT screening test was used to screen patients with alcohol use disorder. A self-report questionnaire …

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Lead Poisoning Among Communication Radio-Repair Workers In Signal Department Royal Thai Army Samutsakhon Province, Thailand, Manasawee Thongsringklee Jan 2019

Lead Poisoning Among Communication Radio-Repair Workers In Signal Department Royal Thai Army Samutsakhon Province, Thailand, Manasawee Thongsringklee

Chulalongkorn University Theses and Dissertations (Chula ETD)

Chronic exposure to low dose of lead can affect to every systems and organs of the human body. Lead poisoning have been found among communication radio-repair workers because lead is routinely used for soldering. The longitudinal study design was used to investigate blood lead level (BLL) and hair lead level (HLL), to determine the association of BLL and HLL with signs and symptoms of lead poisoning among workers and to determine the health risk assessment of lead exposure among workers. There were 66 repair workers in exposed group and 54 office workers in low exposed group at baseline. And, there …

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Breast Self-Examination Among Akha Women In Chiang Rai Province Thailand: Policy Recommendations Based On The Formative Research Study Design, Sirinan Suwannaporn Jan 2019

Breast Self-Examination Among Akha Women In Chiang Rai Province Thailand: Policy Recommendations Based On The Formative Research Study Design, Sirinan Suwannaporn

Chulalongkorn University Theses and Dissertations (Chula ETD)

Background: The mortality rate of breast cancer has increased in several countries in Asia. In Thailand, this fact is confirmed by the hospital–based cancer registry annual report which ranked breast cancer as first of all female cancer patients. One an urgent concern of prevention and education on early detection is Breast Self-Examination (BSE). ‘Akha’ women, the largest ethnic group in Chiang Rai, northern part of Thailand, have a significantly low percentage of BSE practice because of language barrier and other problems. This study aims to identify factors associated with BSE among this ethic group to better understand the reasoning for …

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Effects Of Modified-Continuous Ambulatory Peritoneal Dialysis (Capd) Patient’S Handling Process Among Community Nurses Towards Patient’S Quality Of Life And Treatment Outcomesin Nan Province, Thailand, Prichavijy Promjak Jan 2019

Effects Of Modified-Continuous Ambulatory Peritoneal Dialysis (Capd) Patient’S Handling Process Among Community Nurses Towards Patient’S Quality Of Life And Treatment Outcomesin Nan Province, Thailand, Prichavijy Promjak

Chulalongkorn University Theses and Dissertations (Chula ETD)

Background: Continuous Ambulatory Peritoneal Dialysis (CAPD) is an important kidney replacement therapy that highly increased after increasing ESRD patients which required renal replacement therapy and after the Thai government promoted PD first policy under a universal coverage scheme in the year 2008. The potential advantage of CAPD modality is home therapy which is less costly than haemodialysis nevertheless, CAPD’s patients facing lifelong physical, psychological and social problems related to their illness and its treatment care especially lack CAPD programme in primary care level. Consequently, this study aims to assess the “modified CAPD patient’s handling process” among healthcare providers at the …

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Household Pyrethroid Insecticides Exposure In Relation To Pyrethroid Metabolite And Gaba Level Effects Of Young Children In Urban Area, Bangkok Thailand, Jadsada Kunno Jan 2019

Household Pyrethroid Insecticides Exposure In Relation To Pyrethroid Metabolite And Gaba Level Effects Of Young Children In Urban Area, Bangkok Thailand, Jadsada Kunno

Chulalongkorn University Theses and Dissertations (Chula ETD)

Pyrethroids are commonly used in households and affect to nervous system in children. Data on pyrethroids exposure related to neurotransmitter gamma-aminobutyric acid (GABA) is unknown. This study investigated the relationship between 3-PBA metabolites and GABA concentrations, and also determined the factors influencing pyrethroids metabolites among young children in urban areas. A repeated cross-sectional design was designed to collect the information on PYR insecticide exposure between wet (November – December 2018) and dry (April – May 2019) seasons. To collect the data, urine samples were collected from children age 2–3 years(n = 80), and the questionnaires were used with parents. The …

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Effect Of Peer Support Intervention On Anxiety, Depression And Quality Of Life Among Female Breast Cancer Patients On Chemotherapy In Yangon, Myanmar: Randomized Controlled Trial, Min Thu Naung Jan 2019

Effect Of Peer Support Intervention On Anxiety, Depression And Quality Of Life Among Female Breast Cancer Patients On Chemotherapy In Yangon, Myanmar: Randomized Controlled Trial, Min Thu Naung

Chulalongkorn University Theses and Dissertations (Chula ETD)

Background: The physical and psychological symptoms occurring after diagnosis and during chemotherapy have a negative effect on the quality of life (QOL) of breast cancer patients. Anxiety and depression are also linked with a deprived QOL and prognosis. This study evaluated the effect of peer support intervention on knowledge about chemotherapy, self-efficacy, empathy, consumer satisfaction, anxiety, depression and QOL of female breast cancer patients on chemotherapy in Yangon, Myanmar. Methods: A randomized controlled trial was conducted at Shwe Yaung Hnin Si Cancer Foundation clinic in Yangon. A total of 74 patients participated and they were assigned randomly into an intervention …

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Undernutrition And Its Determinants Among Under-Five Children Of Indigenous Thami Population In Dolakha District, Nepal, Keshav Dahal Jan 2019

Undernutrition And Its Determinants Among Under-Five Children Of Indigenous Thami Population In Dolakha District, Nepal, Keshav Dahal

Chulalongkorn University Theses and Dissertations (Chula ETD)

Undernutrition is a major public health issue leading to morbidity and mortality in children of age under-five, especially with higher rate of prevalence in very low or low-income countries including socially deprived and marginalized group of population. This study was carried out to identify the prevalence of undernutrition and its determinants among under-five children of indigenous Thami population in Dolakha District, Nepal. A community based quantitative cross-sectional study was conducted during the period of August to September 2019 with multistage sampling technique among 366 under-five children and their biological mothers. Anthropometric measurement tools were used to collect the data as …

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Standardization Of Leaf And Stem Of Thunbergia Laurifolia And Quantitative Analysis Of Rosmarinic Acid In Selected Thai Medicinal Plants, Parichart Hongsing Jan 2019

Standardization Of Leaf And Stem Of Thunbergia Laurifolia And Quantitative Analysis Of Rosmarinic Acid In Selected Thai Medicinal Plants, Parichart Hongsing

Chulalongkorn University Theses and Dissertations (Chula ETD)

Rang-Jued or Thunbergia laurifolia Lindl. is a species in family Thunbergiaceae. In Thailand, leaf and stem of T. laurifolia are used to treat fever, inflammation, as well as antidotes. Perilla frutescens (L.) Britton or Nga-Kee-Mon belongs to Labiatae family. The leaf of P. frutescens is used to treat allergy, fever and inflammation. Rosmarinic acid is the active compound in both plants which was used as a standard marker in this study. Quantification of rosmarinic acid in the three samples using TLC-densitometry and TLC-image analysis were not statistically significantly different (P > 0.05). The pharmacognostic specification of T. laurifolia leaf and stem …

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Effects Of Inhaled Essential Oils On Central Nervous System, Autonomic Nervous System, Emotional States And Reaction Time: Randomized Crossover Study, Pakamon Thanatuskitti Jan 2019

Effects Of Inhaled Essential Oils On Central Nervous System, Autonomic Nervous System, Emotional States And Reaction Time: Randomized Crossover Study, Pakamon Thanatuskitti

Chulalongkorn University Theses and Dissertations (Chula ETD)

The odors of essential oils used to cure various symptoms refer to aromatherapy. The effects of inhaled essential oil on humans are therapeutically effective due to both the psychological and physiological effects. A large body of previous studies have been conducted on the effects of essential oil inhalation. However, the studies conducted on the effects on central nervous system and reaction time task are still lacking. Thus, the purpose of this study was to evaluate the effects of selected essential oils including neroli oil (Citrus aurantium Linn.), cinnamon leaf oil (Cinnamomum zeylanicum Blume), and rice paddy herb oil (Limnophila aromatica …

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Prostate Cancer Screening In Thailand: Cost-Effectiveness Analysis And Budget Impact Evaluation, Chavalit Romyen Jan 2019

Prostate Cancer Screening In Thailand: Cost-Effectiveness Analysis And Budget Impact Evaluation, Chavalit Romyen

Chulalongkorn University Theses and Dissertations (Chula ETD)

Objectives: As public health insurance schemes in Thailand did not included prostate cancer screening in their benefits package, this study aimed to systematically gather the effectiveness and explore the cost effectiveness of difference prostate cancer screening programs for the Thai population and find the financial impact for adapting prostate cancer strategy. Method: We perform systematic and network meta-analysis, health economic evaluation using Markov’s model to compare four prostate cancer screening strategies with no screening options. And we perform budget impact analysis to assess the potential burden for adopting selected strategy. Result: The result from systematic review and network meta-analysis suggest …

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Risk Factors For Malaria Infection And Dihydroartemisinin+Piperaquine Resistance Distribution Between High And Low Endemic Areas In Indonesia, Irfanul Chakim Jan 2019

Risk Factors For Malaria Infection And Dihydroartemisinin+Piperaquine Resistance Distribution Between High And Low Endemic Areas In Indonesia, Irfanul Chakim

Chulalongkorn University Theses and Dissertations (Chula ETD)

Globally, malaria case is decreasing over decades. This similar trend happens in Indonesia but it is still not even close to elimination. To control and eradicate malaria require a comprehensive and coincident strategy for the parasite and its vector. However, malaria elimination strategy of many countries, including Indonesia, is still considering only treatment which has led to resistance of Plasmodium species over various antimalarial drugs. Recently, resistance to the only and current available drug, artemisinin, has appeared and spread over continents in the world. However, it has not been extensively discovered in Indonesia. Additionally, it was widely known that a …

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Drug Classification Scheme Review And The Economic Impact Analysis Of Abandoning Non-Prescription Drug Reimbursement In Thailand, Doungporn Leelavanich Jan 2019

Drug Classification Scheme Review And The Economic Impact Analysis Of Abandoning Non-Prescription Drug Reimbursement In Thailand, Doungporn Leelavanich

Chulalongkorn University Theses and Dissertations (Chula ETD)

In Thailand, controversies regarding the drug classification system persist; it was believed that the number of schemes should be changed, and most drugs classified into improper schemes. The system is not also fully used to allocate healthcare budgets, while several other countries cease non-prescription (OTC) drugs reimbursement to allocate this expenditure to catastrophic diseases instead. This study thus aims to (i) review drug classification system in Thailand by comparing to other countries, (ii) evaluate the economic impact of delisting OTC drugs from drug reimbursement list using non-sedating antihistamines (AH) in patients suffering from intermittent allergic rhinitis as a case study, …

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Exploring Alcohol Withdrawal Syndrome And Predicting Alcohol Consumption Change In Patients Admitted To A Genenral Hospitals In Vietnam, Loan Thi Mai Nguyen Jan 2019

Exploring Alcohol Withdrawal Syndrome And Predicting Alcohol Consumption Change In Patients Admitted To A Genenral Hospitals In Vietnam, Loan Thi Mai Nguyen

Chulalongkorn University Theses and Dissertations (Chula ETD)

Risky alcohol drinking is common in hospitalized patients. Early detecting risky alcohol drinkers in hospital is important to provide appropriate management of Alcohol withdrawal syndrome (AWS). This first aim of this study was to identify the extent to which patients admitted to a general hospital in Vietnam meet the criteria for risky alcohol drinker (RAD), alcohol use disorder (AUD), and alcohol withdrawal syndrome (AWS). The second aim was to identify predictors of intension to change and changing alcohol consumption using the Integrated Behavior Model as a conceptual framework. Design: A prospective survey was conducted in Kien An - a general …

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Study Of Pharmacist Workforce In Public Sector, Of Republic Of The Union Of Myanmar, Lwin Nyein Aye Jan 2019

Study Of Pharmacist Workforce In Public Sector, Of Republic Of The Union Of Myanmar, Lwin Nyein Aye

Chulalongkorn University Theses and Dissertations (Chula ETD)

Health workforce shortage was common across the world including Myanmar. However, there was not previous study about the pharmacist workforce to ascertain the shortage problem in Myanmar. This study was aimed to analyze the current situation of pharmacist workforce in Myanmar especially in public sector and to construct a simulation model to suggest the appropriate policy options to the policymakers in improving the pharmacist workforce situations in the public hospitals.For the first objective, the study design was a cross-sectional survey using a mixed method which consisted of the secondary data analysis and semi-structured face-to-face interviews. The government registry data related …

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Precision Medicine Reimbursement Policy Landscape, Nisita Jirawutkornkul Jan 2019

Precision Medicine Reimbursement Policy Landscape, Nisita Jirawutkornkul

Chulalongkorn University Theses and Dissertations (Chula ETD)

Background: Access to precision medicine is limited due to many factors such as precision medicine technology of each country, high-cost technology that requires high finance, limitations on knowledge and competency of personnel and access to precision medicine. Each country manages access to precision medicine differently. The existing evidences of precision medicine reimbursement policy were limited. Objective: To explore reimbursement decision of precision medicine focusing on diagnostic tests and factors associated with reimbursement decision among high-income and upper-middle-income countries. Methods: A targeted review of literatures was conducted through PubMed, MEDLINE, Embase, Cochrane Library, and hand-searching. The study included 13 selected precision …

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Development Of Prediction Model For Chronic Kidney Disease In Type 2 Diabetics In Thailand, Wilailuck Tuntayothin Jan 2019

Development Of Prediction Model For Chronic Kidney Disease In Type 2 Diabetics In Thailand, Wilailuck Tuntayothin

Chulalongkorn University Theses and Dissertations (Chula ETD)

Diabetes mellitus (DM) is a major contributing factor that leads to end stage renal disease (ESRD) with unsuitable clinical management. Chornic kidney disease (CKD) prediction model could prevent the progression of CKD to ESRD. However, current CKD prediction models in patients with type 2 DM were developed to predict ESRD. This study aimed to develop prediction model for CKD stage 3 in patients with type 2 DM in Thailand. This was a 10-year retrospective cohort study obtaining data of patients with type 2 DM from electronic database of Taksin hospital during 1 January 2008 to 31 December 2017. The outcome …

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Situation Analysis Of Drug Product Information Provision In Yangon And Review On Consumer Drug Information Guidelines Across Countries, Zar Ni Win Jan 2019

Situation Analysis Of Drug Product Information Provision In Yangon And Review On Consumer Drug Information Guidelines Across Countries, Zar Ni Win

Chulalongkorn University Theses and Dissertations (Chula ETD)

The appropriate drug use and successful treatment relies heavily on how patients administer medicines by themselves and thus healthcare knowledge and drug information become crucial for them. Firstly, content analysis was conducted to evaluate drug product information attached with the 30 drug samples of three drug classes. To evaluate written and verbal drug information, standardized simulated patient survey was conducted by using Mefenamic Acid provided in community pharmacies around Yangon. In the second step of this study, targeted literature review was performed to identify and compare different regulations of PILs and PIL development guidelines in terms of contents, designs and …

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Social Integration Of Chinese Students In Thai Society: The Case Of Chinese Students In Chulalongkorn University And Dhurakij Pundit University, Caoyi Zhang Jan 2019

Social Integration Of Chinese Students In Thai Society: The Case Of Chinese Students In Chulalongkorn University And Dhurakij Pundit University, Caoyi Zhang

Chulalongkorn University Theses and Dissertations (Chula ETD)

International students may not integrate as successfully and smoothly as has been assumed. These students may experience multiple challenges in their new social and academic host environments. As Chinese student is the majority and the main source of international students in Thailand, promotion for their better integration into Thai society should be done. Therefore, this study aims to investigate social life of Chinese students in Thailand and the factors that influent Chinese students’ integration into Thai society. The author chosen two representative universities as case study. The data was collected from observation and semi-structured interviews about integration in various domains …

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The Popularity And The Localization Of Muay Thai In California, Usa, Andrew Rudolph Sorrells Jan 2019

The Popularity And The Localization Of Muay Thai In California, Usa, Andrew Rudolph Sorrells

Chulalongkorn University Theses and Dissertations (Chula ETD)

Muay Thai as the traditional martial art of the Thai people. In the last few decades, Muay Thai has spread throughout the world. The International Federation of Muay Thai Amateurs (IFMA), based in Bangkok, boasts 130 member countries. One of the places Muay Thai spread to and became popularized is California, USA. This paper is an ethnographic study of the phenomenon of how the Thai martial art of Muay Thai has been popularized and localized in California. I did field work at Muay Thai gyms in California and Thailand where I observed the different traditions, practices, and training methodologies. I …

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Loyalty Of Taylor Swift's Fans And Their Uses Of Social Media During Crisis Regarding Music Ownership Controversy, Nidawan Asavataweechok Jan 2019

Loyalty Of Taylor Swift's Fans And Their Uses Of Social Media During Crisis Regarding Music Ownership Controversy, Nidawan Asavataweechok

Chulalongkorn University Theses and Dissertations (Chula ETD)

The objectives of this research were to study fans loyalty, fans’ perception on crisis management of Taylor Swift, and their uses of social media and to explore the relationship among these three variables. Two hundred and twenty-three respondents who are Taylor Swift’s fans, aged between 18 and 35 years old were asked to complete an online questionnaire survey. The results depicted that the respondents had a positive opinion about fans loyalty (M = 4.39). Moreover, the respondents had a positive perception on crisis management of Taylor Swift (M = 4.53) and use social media in a positive way (M = …

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Building Trust Through Innovative Trust Building Process : The Case Of Organic Food Market In Thailand, Supranee Tangnatthanakrit Jan 2019

Building Trust Through Innovative Trust Building Process : The Case Of Organic Food Market In Thailand, Supranee Tangnatthanakrit

Chulalongkorn University Theses and Dissertations (Chula ETD)

The organic food industry is currently faced with challenges of consumer mistrust due to the current food supply chain issues concerning the reliability of information, supply chain transparency, product quality, logistic issues, environmental impact, fraud, and food safety. Although receiving certification from the authorized institutions is one way of building consumer trust, it remains a cumbersome process. In addition, consumers are increasingly looking to develop trust through other sources, such as searching for information that relates to the reputation of the retailers or the credibility of the producers. While trust has been generally defined in previous trust-related studies as the …

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Single Fixed-Time Artificial Insemination With Fresh Or Frozen Thawed Semen In Pig, Pachara Pearodwong Jan 2019

Single Fixed-Time Artificial Insemination With Fresh Or Frozen Thawed Semen In Pig, Pachara Pearodwong

Chulalongkorn University Theses and Dissertations (Chula ETD)

Single fixed-time AI is the breeding protocol inseminating the sows once with either fresh or frozen-thawed (FT) semen at fixed time after ovulation induction without estrus detection. To develop the success single fixed-time AI protocol in Thailand, factors affecting the efficacy of single fixed-time AI were evaluated. Additionally, we also evaluated the effect of using lecithin in cryopreservation extender on FT semen qualities in order to find the possibility to perform single fixed-time AI using sperm preserved in lecithin based extender. It was found that administration of 10 ug buserelin at 72 h after weaning decreased weaning-to-ovulation interval compared to …

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Development Of An Indirect Elisa To Detect Antibodies Against Actinobacillus Suis Using Boiled Whole Cell Antigen, Siriluck Juntautsa Jan 2019

Development Of An Indirect Elisa To Detect Antibodies Against Actinobacillus Suis Using Boiled Whole Cell Antigen, Siriluck Juntautsa

Chulalongkorn University Theses and Dissertations (Chula ETD)

Actinobacillus suis is considered an opportunistic pathogen in swine that can cause disease in animals of all ages, especially in high health status herds. The objective of this study was to developed an indirect enzyme-linked immunosorbent assay (ELISA) using boiled whole cell antigen for the detection of antibody against A. suis. The selected herd has clinical problems associated with A. suis infection. In addition, this herd was not received any Actinobacillus pleuropneumoniae (APP) vaccine nor diagnosed with APP infection before the study. The isolation of A. suis was recovered from lung of the infected pig in the selected herd. Moreover, …

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Short Term Effects Of Sildenafil In Treatment Of Pulmonary Hypertension In Degenerative Mitral Valve Disease Dogs, Karun Saetang Jan 2019

Short Term Effects Of Sildenafil In Treatment Of Pulmonary Hypertension In Degenerative Mitral Valve Disease Dogs, Karun Saetang

Chulalongkorn University Theses and Dissertations (Chula ETD)

Degenerative mitral valve disease (DMVD) is the most common acquired cardiac disease in small breed dogs. Pulmonary hypertension (PH) is a common complication in DMVD that can worsen the clinical signs, cardiac function, and median survival time of DMVD dogs. Conventional therapy of DMVD can reduce systolic pulmonary arterial pressure (sPAP) minimally. Thus, additional therapy is required. Sildenafil is used to treatment of PH in various causes, but the effect of sildenafil in the treatment of PH secondary to DMVD is not published yet. Therefore, this study aimed to evaluate the effects of sildenafil in combination with conventional therapy in …

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Institutional Dynamics And Adaptive Capacity In World Heritage Management: Case Studies From Southeast Asia, Montira Unakul Jan 2019

Institutional Dynamics And Adaptive Capacity In World Heritage Management: Case Studies From Southeast Asia, Montira Unakul

Chulalongkorn University Theses and Dissertations (Chula ETD)

Over the past 40 years, heritage site management institutions have had to contend with expanding “boundaries of practice”: the evolution of heritage concepts and the emergence of global and transnational threats and broader sustainable development issues. Yet, many heritage site management institutions are still mired in conventional heritage mandates and approaches. This study looks at the ability of World Heritage site management institutions to adapt to this changing landscape. Global monitoring exercises show that World Heritage sites are struggling with this increased complexity, with many sites under active monitoring, sometimes for years. The sluggishness of change suggests that a deeper …

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The Invention Of Plastic Plate For The Semiquantitative Detection Of Somatic Cells In Farm Bulk Tank Milk, Piyarat Jiarpinitnun Jan 2019

The Invention Of Plastic Plate For The Semiquantitative Detection Of Somatic Cells In Farm Bulk Tank Milk, Piyarat Jiarpinitnun

Chulalongkorn University Theses and Dissertations (Chula ETD)

Bulk tank milk somatic cell count (BTM SCC) is worldwide acceptable as an indicator of subclinical mastitis and milk quality at the farm level. Several countries determine the BTM SCC level for quality control and milk pricing. In Thailand, BTM SCC standard is set at 500,000 cells/ml and premium milk quality is set at less than 100,000 cells/ml. Milk collecting centers (MCCs) use CMT (California Mastitis Test) for screening raw milk quality. However, CMT has an error and high variation. This study aims to invent a new semiquantitative device for determining BTM SCC and to validate the device in comparison …

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Assessment Of Left Atrial Function In Feline Hypertrophic Cardiomyopathy By Using Two Dimensional Speckle Tracking Echocardiography, Arisara Kiatsilapanan Jan 2019

Assessment Of Left Atrial Function In Feline Hypertrophic Cardiomyopathy By Using Two Dimensional Speckle Tracking Echocardiography, Arisara Kiatsilapanan

Chulalongkorn University Theses and Dissertations (Chula ETD)

Hypertrophic cardiomyopathy (HCM) is one of the most common myocardial diseases in cats. The left atrial (LA) function plays an essential role in compensatory mechanism of left ventricle with diastolic dysfunction to maintain cardiac output in cats affected with HCM. Nowadays, there are several echocardiographic techniques used to evaluate the left atrial function; however, each technique has limitations. To overcome the limitations, two-dimensional speckle tracking echocardiography (2D-STE) is a novel technique for assessment the LA function. To date, no study focusing on assessment of the left atrial function by 2D-STE in feline HCM has been reported. The objective of this …

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Vector Competence Of Culex Tritaeniorhynchus For Duck Tembusu Virus, Jitra Sanisuriwong Jan 2019

Vector Competence Of Culex Tritaeniorhynchus For Duck Tembusu Virus, Jitra Sanisuriwong

Chulalongkorn University Theses and Dissertations (Chula ETD)

Duck Tembusu virus (DTMUV), an emerging infectious disease in ducks, belongs to the Ntaya virus group of the Flavivirus genus in the Flaviviridae family. The emergence of DTMUV has been observed in layer and breeder duck farms in China since 2010 and in layer and broiler duck farms in Thailand since 2013. Infected ducks show neurologic signs, including an incapability to stand, ataxia, and paralysis. A significant drop in egg production is usually observed among layer ducks. The transmission of DTUMV involves mosquito vectors, however, the exact role of mosquitoes in the ecology of DTMUV in Thailand remains unclear. The …

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Development Of Mucoadhesive Nanovaccine Against Columnaris Disease In Red Tilapia (Oreochromis Sp.), Sirikorn Kitiyodom Jan 2019

Development Of Mucoadhesive Nanovaccine Against Columnaris Disease In Red Tilapia (Oreochromis Sp.), Sirikorn Kitiyodom

Chulalongkorn University Theses and Dissertations (Chula ETD)

Tilapia (Oreochromis sp.) is very important and high production of freshwater fish in Thailand. Columnaris disease has been now recognized as one of the most serious infectious diseases in farmed tilapia. The disease is caused by Flavobacterium columnare. Among the prevention and control strategies, vaccination is one of the most effective approach. According to the pathogenesis of this bacteria, the characteristic lesion is almost at mucosal area of skin and gill. Therefore, hypothesized that the mucosal nanovaccine with mucoadhesive characteristic could be suitable vaccination method to control columnaris disease. In this study, we determined vaccine strain candidate by clinical field …

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Epidemiological Surveillance Of Feline Morbillivirus Infection In The Aspects Of Polymerase Chain Reaction, Indirect Elisa And Immunohistochemistry, Surangkanang Chaiyasak Jan 2019

Epidemiological Surveillance Of Feline Morbillivirus Infection In The Aspects Of Polymerase Chain Reaction, Indirect Elisa And Immunohistochemistry, Surangkanang Chaiyasak

Chulalongkorn University Theses and Dissertations (Chula ETD)

Feline morbillivirus (FeMV), a relatively new virus, has been discovered in domestic cats and associated with kidney diseases since 2012 in Hong Kong. The FeMV study gained widely attentions in many countries whereas the pathogenesis remains elusive. These studies aimed to provide the FeMV knowledge in Thai domestic cat by performing the genetic-based, serological-based and pathological-based studies of FeMV-infected in Thai cats. Additionally, the indirect enzyme linked immunosorbent assay (ELISA) and rabbit polyclonal antibody against FeMV matrix (FeMV-M) protein was produced for seroprevalence and viral localization by immunohistochemistry (IHC) techniques, respectively. Our results revealed the FeMV RNA prevalence at 11.9% …

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