Digital Commons Network^™

Predictive Factors For Invasive Fungal Rhinosinusitis In Diabetic Patients, Thwe Phyo Kan Nyunt

Chulalongkorn University Theses and Dissertations (Chula ETD)

ภูมิหลัง ผู้ป่วยเบาหวานมีโอกาสที่จะเกิดโรคไซนัสอักสบจากเชื้อราชนิดรุกรานได้ง่ายกว่าผู้ป่วยปกติ ซึ่งอัตราการเสียชีวิตจากโรคนี้ในผู้ป่วยเบาหวานมีความหลากหลายค่อนข้างสูงในแต่ละการศึษา วัตถุประสงค์ เพื่อศึกษาปัจจัยที่จะทำนายอัตราการรอดชีวิตของผู้ป่วยเบาหวานที่เกิดโรคไซนัสอักสบจากเชื้อราชนิดรุกราน วิธีการศึกษา การศึกษาแบบย้อนหลังนี้ได้จัดทำในโรงพยาบาลระดับตติยภูมิ 4 แห่ง ในประเทศไทย, มาเลเซีย และเมียนมาร์ โดยเก็บรวบรวมข้อมูลในผู้ป่วยเบาหวานที่เกิดโรคไซนัสอักสบจากเชื้อราชนิดรุกราน ตั้งแต่ปี ค.ศ. 2008 ถึง ค.ศ.2019 ผลที่ต้องการศึกษาคืออัตราการรอดชีวิต ปัจจัยทำนายที่นำมาวิเคราะห์ ได้แก่ อายุ, ระดับฮีโมโกลบินเอวันซีในเลือด, ภาวะเลือดเป็นกรดคีโต, ระดับเม็ดเลือดขาว, ภาวะน้ำตาลในเลือดสูง, ระยะเวลาที่เป็นโรคเบาหวาน, การใช้ยารักษาเบาหวานในปัจจุบัน, ระดับครีเอทีนีนในเลือด, และการกระจายของโรคไซนัสอักสบจากเชื้อราชนิดรุกรานเข้าไปที่ตา, คาเวอร์นัสไซนัส และโพรงสมอง ผลการศึกษา มีการเก็บรวบรวมข้อมูลในผู้ป่วยเบาหวานที่เกิดโรคไซนัสอักสบจากเชื้อราชนิดรุกราน 65 ราย (อายุเฉลี่ย 57.9±13.4 ปี, เพศชาย 60%) ผลพบว่า อัตราการเสียชีวิตอยู่ที่ 21.5 % โดยพบว่าการกระจายของโรคไซนัสอักสบจากเชื้อราชนิดรุกรานเข้าคาเวอร์นัส ไซนัส (hazard ratio 5.1, 95% CI [1.4–18.2], p=0.01) และโพรงสมอง (hazard ratio 3.4, 95% CI [1.1–11.3], p=0.05) เป็นปัจจัยทำนายอัตราการเสียชีวิต ส่วนการรักษาเบาหวานเป็นปัจจัยที่ลดความเสี่ยงของการเสียชีวิต (hazard ratio 0.2, 95% CI [0.1–0.9], p=0.03) ด้านอัตราการรอดชีวิตในระยะเวลา 6 เดือนในผู้ป่วยที่มีการกระจายของโรคไซนัสอักสบจากเชื้อราชนิดรุกรานเข้าไปและไม่เข้าไปที่คาเวอร์นัสไซนัสอยู่ที่ 51.4% และ 83.6% ตามลำดับ, (p <0.01), เข้าไปและไม่เข้าไปที่โพรงสมองอยู่ที่ 53.3% และ 88.9% ตามลำดับ, (p <0.01) และมีการใช้ยารักษาเบาหวานและไม่มีการใช้ยารักษาเบาหวานอยู่ที่ 82.3% และ 57.5% ตามลำดับ, (p =0.05) สรุป การกระจายของโรคไซนัสอักสบจากเชื้อราชนิดรุกรานเข้าไปที่คาเวอร์นัสไซนัสและโพรงสมองเพิ่มความเสี่ยงต่อการเสียชีวิตในผู้ป่วยเบาหวาน การรอดชีวิตมีความสัมพันธ์กับการใช้ยารักษาเบาหวานในปัจจุบัน

Access To Malaria Diagnostic Testing, Anti-Malarial Treatment And Long-Lasting Insecticidal Nets Among Immigrant Workers In Yala Province, Southern Thailand, Tinzar Naing

Chulalongkorn University Theses and Dissertations (Chula ETD)

Background: In Southeast Asia, trans-border migration from neighboring countries into Thailand is a well-known phenomenon. Population movement and migration is a factor having significant implications for vector-borne disease transmissions. Objectives: This study aims to assess migrants’ access to malaria diagnosis and treatment in Yala province who have had fever in the previous three months and to evaluate the coverage and utilization of ITNs (insecticidal nets). Methodology: A survey was conducted among 414 immigrant workers, in which information was sought on socio-demography, history of fever, health seeking behaviours, net ownership and utilization. Survey analysis was employed. Results: As key findings, 36.5% …

Evaluation Of The Outcomes And Regression Rate After Early Treatment For Retinopathy Of Prematurity Treatment In King Chulalongkorn Memorial Hospital, Yothin Titawattanakul

Chulalongkorn University Theses and Dissertations (Chula ETD)

Primary objectives: To study the unfavorable outcomes and assess the regression rate after early treatment protocol for the ROP in KCMH. - Secondary objectives: To study the complications and evaluate the progression and recurrence of ROP requiring retreatment after early treatment protocol for the ROP in KCMH. To identify the independent risk factor for the Retinopathy of Prematurity development in KCMH. - Design: The Retrospective descriptive study and retrospective cohort study. - Participants: The study included all premature infants who were screened ROP in King Chulalongkorn Memorial Hospital from January 2009 to January 2014. - Method: The data retrieved from …

Heuristics Used In Credibility Judgment Of Health Information On Facebook, Yaninee Petcharanan

Chulalongkorn University Theses and Dissertations (Chula ETD)

Facebook users worldwide had been facing challenges of information credibility. This study aimed to address this issue among Thai Facebook users by focusing on health information in particular, through a lens of heuristic approach. Data were collected from 50 informants by in-depth interviews and 480 responses from online surveys. All participants were at least 18 years old with a minimum of one year experience in using Facebook. The results revealed three different processes and five heuristics, namely, reputation heuristic, authority heuristic, expectancy violation heuristic, persuasive intense heuristic, and bandwagon heuristics that participants adopted when making a credibility judgment of health …

In Vitro Safety And Permeation Assessments Of Lidocaine Loaded In Dissolving Microneedle Patch For Ocular Administration, Sirikool Thamnium

Chulalongkorn University Theses and Dissertations (Chula ETD)

The challenge in ocular drug delivery have brought much attention in pharmaceutical research. Efforts have been made to improve the low bioavailability causing by physiological limitations of ophthalmic drug administration. Topical lidocaine solution is a popular choice for ocular treatment, but less than 5% of topically applied dose reached to the target site. Lidocaine loaded in dissolving microneedle patch was considered a good alternative approach to treating eyes. The study aimed to investigate the cytotoxicity of the lidocaine loaded in dissolving microneedle administration against human corneal epithelial cells (HCECs) as well as ex vivo drug target localization with tissue penetration. …

Effect Of Extraction Solvents On Biological Activities Of Murraya Paniculata Leaves In Cosmetic Application, Siriruethai Ruanmai

Chulalongkorn University Theses and Dissertations (Chula ETD)

The objective of this study was to evaluate and compare the antioxidant activity and tyrosinase inhibition activity of Murraya paniculata (Linn.) Jack leaves extract (MPE) obtained from different extraction solvents for the use of cosmetic purposes. The result showed that 75 % ethanolic extract presented the highest antioxidant activity (IC50 = 1.43 mg/mL), the total phenolic content of 66.12 mg GAE/g and the total flavonoids content of 7.83 mg QE/g. All of the obtained extracts had low tyrosinase inhibitory activity. The final MPE lotion contained 1 %w/w of 75 % ethanolic extract dissolved in 50 %w/w of propylene glycol, 20 …

Projection And Determinants Of Cognitive Ability Among Older Persons In Thailand : Role Of Education, Paolo Miguel Vicerra

Chulalongkorn University Theses and Dissertations (Chula ETD)

This thesis examines the role of education on cognitive ability among the older population of Thailand. The nationally-representative data primarily utilised in this thesis is 2016 Population Change and Well-being in the Context of Aging Society. Other datasets had been used in selected themes within this thesis. Multiple analytic approaches had been applied to this study to show various effects of education gradients on cognitive functioning. In the first study, education and other covariates including income, health status, living arrangement, and social participation among others had been analysed by gender to test if the significant factors would be similar. It …

Wage Compensation Differentials For Job Risk Between Formal And Informal Workers, Pinyada Suwannarat

Chulalongkorn University Theses and Dissertations (Chula ETD)

This research estimates compensating wage differentials for job risks for formal and informal workers in Thailand, the latter of whom are not covered by prevailing labor laws. Using data from the National Statistical Office’s Thai Labor Force Survey for years 2012 to 2018 merged with job fatality risk collected by the Social Security Office, the results show that the fatality risk rate has a positive, significant effect on wages. The value of statistical life for the median formal workers is 79.33 million baht compared to 41.5 million baht for the median informal worker. Also, we analyze the relationship between self-reported …

Effects Of Upper Extremity Positions And Movements And Breathing Patterns On Chest Wall Kinematics And Sensation Of Dyspnea In Patients With Chronic Obstructive Pulmonary Disease, Chathipat Kruapanich

Chulalongkorn University Theses and Dissertations (Chula ETD)

The objectives of this study were to 1) study the influences of the upper extremity (UE) positions and 2) the combination of UE movements coordinated with breathing patterns on chest wall movements and sensation of dyspnea in patients with chronic obstructive pulmonary disease (COPD). Furthermore, the results were also compared to those of the healthy subjects. We invited forty-two subjects, 21 patients with mild to moderate COPD whose aged, gender, and physical activity were matched to healthy subjects, to participate in this study. In the first part of this study, all participants’ chest wall movements and dyspnea were evaluated while …

Development Of Ecoregion Criteria Through Assessment Of Changing Floating Vegetation: A Case Study Of Intha Communities In Inlelake, Myanmar, Saint N/A

Chulalongkorn University Theses and Dissertations (Chula ETD)

The Inle Lake ecoregion, one of the fresh water ecoregions in the Global 200 list of ecoregions, is facing impacts of sedimentation from upland catchments. Sediment loads and soil sediment characteristics from degraded forest of Kalaw catchment shallowed and reduced plant nutrients in the Inle Lake ecosystems where used to be well recognized for the balancing between Intha livelihoods and natural production of littoral and pelagic zones. This study aimed to assess causes of ecological function change in terms of high sediment loads influencing Intha livelihoods; floating vegetation and to propose criteria for ecoregion development concerning sustainable floating vegetation yields …

Microencapsulation Of Probiotics Using Goat Milk And Konjac Glucomannan Hydrolysate Via Spray Drying, Sudhinee Harindhanavudhi

Chulalongkorn University Theses and Dissertations (Chula ETD)

Probiotics are beneficial for health when consuming in a sufficient amount. However, probiotics are not tolerant to high temperatures in food processing. Microencapsulation is one technique that using to entrap probiotic cells for applying in food products. Therefore, this research is aimed to study the application of konjac glucomannan hydrolysate (KGMH) in the combination of goat milk to encapsulate Lb. casei-01 by using microencapsulation techniques via spray drying. There were three main parts of this research. Firstly, KGMH from 15-25% (w/w) KGM were determined for prebiotic activity score (PAS) in in vitro. Besides, the positive effect of KGMH in goat …

Replacement Of Milk Fat With Other Fats In Processed Cheese Analogues, Pachara Pomsang

Chulalongkorn University Theses and Dissertations (Chula ETD)

This research is aimed to develop healthy processed cheese for Thai consumers by studying consumer needs, the physicochemical and sensory properties of the developed processed cheese. Thai consumers who concerned about their health in Bangkok (n=422) participated in a survey and 72.7% of the consumers had positive intention to the healthy cheesed product in sliced type. Eighty percent of the consumers expected their cheese product to be fortified with healthy ingredients such as antioxidants and omega fatty acids. Four processed cheese prototypes with different milk fat replacements (rice bran oil (RBO), soybean oil (SBO), palm oil (PO), and fish oil …

การสังเคราะห์งานวิจัยที่เกี่ยวข้องกับวิธีการวัดความสว่างของป้ายไฟ, ประดิษฐ์ สาระอ่อน

Chulalongkorn University Theses and Dissertations (Chula ETD)

งานวิจัยนี้มีวัตถุประสงค์เพื่อศึกษาตัวแปรที่เกี่ยวข้องกับวิธีการวัดความสว่างของป้ายไฟ ใช้วิธีการสังเคราะห์ เอกสาร โดยใช้คำสำคัญที่เกี่ยวข้องกับวิธีการวัดความสว่างป้ายไฟ การสืบค้นเอกสารในฐานข้อมูลออนไลน์ ในช่วงระหว่าง ปี พ.ศ. 2540 – 2562 กลุ่มตัวอย่างในการวิจัยที่นำมาสังเคราะห์ คือ บทความวิจัย วิทยานิพนธ์ และรายงานเชิงเทคนิค จำนวน 39 เรื่อง แล้วนำมาจำแนกข้อมูลด้วยแบบบันทึกคุณลักษณะเอกสาร จากนั้นทำการคัดเลือกเอกสารที่ตรงตาม เกณฑ์การคัดเลือก ได้จำนวน 15 เรื่อง การวิเคราะห์ข้อมูลในการศึกษาครั้งนี้เป็นการวิเคราะห์เชิงคุณลักษณะ โดยแบ่ง ออกเป็นสามกลุ่ม กลุ่มแรกเป็นข้อมูลทั่วไปของเอกสารกลุ่มตัวอย่าง กลุ่มที่สอง เป็นตัวแปรที่เกี่ยวข้องกับการวัดความ สว่าง และกลุ่มที่สาม เป็นวัตถุประสงค์ของการศึกษาที่ส่งผลต่อการเลือกเครื่องมือวัดและวิธีการวัดความสว่างป้ายไฟ ผลการวิเคราะห์ข้อมูลจากกลุ่มตัวอย่างสามารถสรุปได้ดังนี้ 1.) ลักษณะของป้ายไฟ ได้แก่ ป้ายไฟแบบภาพนิ่ง และป้ายไฟแบบภาพเคลื่อนไหว 2.) เครื่องมือวัดความสว่างป้ายไฟ ได้แก่ Luminance meter, HDR Camera และ Imaging Photometer 3.) ตัวแปรที่เกี่ยวข้องกับการวัดความสว่างป้ายไฟ ได้แก่ ลักษณะของป้ายไฟ ความสูงของการ ติดตั้งป้ายไฟ ระยะห่างของการวัด ขนาดของป้ายไฟ และสภาพพื้นที่หรือบริบทที่ทำการวัดป้ายไฟ 4.) วิธีการวัดความ สว่างของเครื่องมือ Luminance meter ได้แก่ การวัดแบบหลายจุดแล้วหาค่าเฉลี่ย การวัดแบบจุดซ้ าที่จุดเดิมแล้วหา ค่าเฉลี่ย การวัดแบบสัดส่วนสี และการวัดแบบต่อเนื่องโดยต่อสายสัญญาณ 5.) เครื่องมือวัดทุกชนิดสามารถใช้วัดความ สว่างป้ายไฟแบบภาพนิ่งได้ ส่วนป้ายไฟแบบภาพเคลื่อนไหวจำเป็นต้องใช้เครื่องมือ luminance meter ด้วยวิธีการวัดซ้ำและการวัดต่อเนื่องด้วยการต่อสายสัญญาณ

Long Term Effects Of Involvement In The Criminal Justice System: Mitigating Collateral Consequences & Tackling Voter Disenfranchisement, Symposium Session 1, Wesley Caines, Lucy Cutolo, Kendea Johnson

Cardozo Journal of Equal Rights & Social Justice

The symposium examines the long-term effects of involvement in the criminal justice system, focusing on collateral consequences and voter disenfranchisement. It emphasizes the need for both prosecutors and defense attorneys to address these consequences early in criminal cases, as they significantly impact individuals' lives beyond direct legal penalties. The discussion highlights the importance of holistic approaches to mitigate these effects and advocates for systemic changes to reduce disparities and support successful reintegration into society.

Long Term Effects Of Involvement In The Criminal Justice System: Mitigating Collateral Consequences & Tackling Voter Disenfranchisement, Symposium Session 2, Sean Morales-Doyle, Anthony Posada, Sebastian Solomon

Cardozo Journal of Equal Rights & Social Justice

No abstract provided.

Annotated Legal Bibliography

Cardozo Journal of Equal Rights & Social Justice

No abstract provided.

Development Of A Descriptive Model Of Flow Disruption Effect On Bypass Time In A Cardiovascular Operating Room, Timothy J. Disher

Doctoral Dissertations and Master's Theses

The current paper proposes utilizing extant flow disruption data, collected from two cardiovascular operating rooms, and utilizing that to develop a mathematical model. Of particular interest is bypass time which is a critical surgical phase, the length of which has been linked to post-operation complications such as hospital-borne infections and readmission. By developing a model that predicts bypass time, the present research can determine the impact by types of flow disruptions – coded based on the RIPCHORD-TWA taxonomy, team member disrupted, and where in the surgery the FD occurs.

After a review of literature, a variety of models were explored …

Communities And Libraries In Times Of Crisis: A Journey Of Knowledge Inquiries In South Carolina, Feili Tu-Keefner

Faculty Publications

In October 2015, several counties in South Carolina experienced catastrophic flooding that caused severe damage. Using a framework for risk communication preparedness and implementation recommended by public health experts, this study investigated public libraries and their legitimacy as partners of public health agencies during and after a disaster. The results show that the libraries in the areas affected created disaster-recovery centers, illustrating their value in facilitating emergency response and recovery. However, the findings also show librarians were not fully prepared to provide disaster and health information, especially through online venues. Information and technology literacy issues created barriers for community members …

The Lived Experience Of Work And Career Among Individuals With Bipolar Disorder: A Phenomenological Study Of Discussion Forum Narratives, Susan R. Rathbun-Grubb

Faculty Publications

Individuals with invisible chronic illnesses are often at a disadvantage in the workplace in terms of job security, promotion, and occupational success. Because little is known about the use of public online support forums to help patients with mental health disorders cope with the impact their illness has on their work and career, this research identifies and examines online forum posts related to employment by contributors with bipolar disorder. Seven percent of the total eligible posts from four discussion forums (n = 7,712) contained mentions of work and career (n = 572). A thematic analysis of the 572 posts is …

"Like Two Beach Umbrellas Put Together": Investigating The Health Information Practices Of South Carolina Lgbtq+ Communities, Vanessa Kitzie, Travis L. Wagner, Valerie A. Lookingbill, Alexander N. Vera

Faculty Publications

This poster presents initial findings from an exploratory, qualitative study investigating the health information practices of LGBTQ+ communities in South Carolina (SC). Significant health disparities exist between LGBTQ+ people and their cisgender, heterosexual counterparts. An important but under-researched barrier producing disparities is informational, as LGBTQ+ people face challenges in learning about their healthcare needs, navigating the healthcare system, and overcoming barriers to care. This study addresses research gaps via the following questions: 1) How do LGBTQ+ communities create, seek, share, and use health information?, and 2) What social and structural factors affect these health-related information practices?Findings are informed by ~30 …

Resituating Public Library Values To Leverage The Health Information Practices Of South Carolina Lgbtq+ Communities, Vanessa Kitzie, Travis L. Wagner, Alexander N. Vera, Valerie A. Lookingbill

Faculty Publications

No abstract provided.

We Try To Find Something For Whatever Obstacle Might Be In Our Way": Understanding The Health Information Practices Of South Carolina Lgbtq+ Communities, Vanessa Kitzie, Travis L. Wagner, Valerie A. Lookingbill, Alexander N. Vera

Faculty Publications

Title: “We Try to Find Something for Whatever Obstacle Might be in Our Way”: Understanding the Health Information Practices of South Carolina LGBTQ+ Communities Objective: LGBTQ+ people experience health disparities compared to heterosexual, cisgender peers. Individual and systemic barriers produe these disparities. One barrier is informational, as LGBTQ+ people experience challenges when learning about their health needs, navigating the healthcare system, and overcoming obstacles to care. This paper investigates the future of libraries and the health sciences by exploring how they can address these informational barriers. Methods: This paper reports on ~30 ongoing interviews with LGBTQ+ community leaders from South …

A Knowledge Lens: Humans In Action, Darin S. Freeburg

Faculty Publications

Every member of a social system sees that system in a particular way. This essay outlines a

new way of seeing the uniquely human characteristics in these systems, with particular attention to what happens when this view is taken. Termed the Knowledge Lens, this view embraces complexity, sees the potential of innovation through conversation, and understands the barriers limiting the traditionally assumed powers of data, information, and knowledge. This lens is approached within the context of ensuring that graduates of a Knowledge School are equipped with the tools and understanding necessary to facilitate positive change and increase human agency--both in …

Culture And Heritage: A Foundation For Sustainable Development Through Understanding And Tolerance Of Cultural Differences, Melodena Stephens, Shamma Bint Sultan Bin Khalifa Al Nahyan, Frederik Panz, Filareti Kotsi

All Works

No abstract provided.

Coming Of Age In The Rio Grande Valley: Race, Class, Gender, And Generations In Narco Culture, Rosalynn A. Vega

Anthropology Faculty Publications

Based on ethnographic observations in the Rio Grande Valley of South Texas, this article examines the multiple, overlapping, criss-crossing axes of inequality that both shape and fracture the experiences of individual borderland residents. Instead of focusing on the national border, this article analyzes intersecting axes of social inequality and uses ethnographic data to describe social borders that divide and separate those living in the borderlands. Using ethnographic data culled from 133 young adults in focus group settings, this article merges the theory of intersectionality with border studies scholarship in order to analyze how socio-economic stratification, gender inequality, histories of racial …

Justice Kennedy And The First Amendment, David L. Hudson Jr.

Law Faculty Scholarship

This essay reviews some of Justice Anthony Kennedy’s most significant contributions to First Amendment jurisprudence. These include his calls for absolute protection for pure political speech, his strong protection for commercial speech, his distaste for campaign finance reform laws that censored speech, his general concern for the silencing of sexual expression, his coercion test in Establishment Clause cases, and his significant failure in the public-employee free-speech decision Garcetti v. Ceballos.

The Popular Constitutional Canon, Thomas G. Donnelly

Law Faculty Publications

Popular constitutionalism scholarship has often left out the American people. Sure, ordinary citizens make cameo appearances—often through the actions of elected officials and elite movement leaders. However, focusing on high politics among elite actors—even if those actors are not judges—simply is not enough. If popular constitutional views do, indeed, matter, then we can expect constitutional partisans to try to manipulate the processes through which these views emerge. Some constitutional scholars have made a start, reflecting on the importance of the constitutional canon. However, these scholars focus mostly on the legal canon and often ignore its popular analog. At the same …

Copyrights In Higher Education: Motivating A Research Agenda, Jacob H. Rooksby

Law Faculty Publications

The Bayh–Dole Act of 1980 enabled American universities to engage in technology transfer. Thirty years of research has investigated the legislation’s effectiveness and derivative university practices, such as the establishment of technology transfer offices. Unfortunately, the technology transfer literature has focused primarily on patenting as the primary transfer vehicle for protecting intellectual property in universities, overlooking other forms of IP ownership, such as copyrights. Legal scholarship shows, however, that universities are increasingly using copyrights to protect their intellectual property and that the number of university-held copyrights exceeds patents. This paper examines the use of copyrights to protect and transfer university …

Unjust Timing Limitations In Genetic Malpractice Cases, Lauren E. Clatch

Law Faculty Publications

As genomic data are increasingly being collected and applied in clinical care, physicians, laboratories, and other health care providers are more frequently being sued for alleged medical malpractice or negligence. Because the genetic underpinnings of an existing or future health condition may not be immediately apparent, such cases sometimes raise unique timing issues involving the applicable statute of limitations, statute of repose, or statutory notification requirements. Although these timing limitations on when a lawsuit can be brought have important policy rationales and justifications, such as helping to protect providers from open-ended liability, their application to genetic liability cases may sometimes …

Catalog 2019-2020, University Of North Florida

UNF Course Catalogs

No abstract provided.